Mus musculus

9 known processes

Phlpp1

PH domain and leucine rich repeat protein phosphatase 1

(Aliases: AI836256,Phlpp,mKIAA0606,SCOP,Plekhe1)

Phlpp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 97 0.407
positive regulation of cellular catabolic process GO:0031331 148 0.367
ras protein signal transduction GO:0007265 77 0.356
positive regulation of ras gtpase activity GO:0032320 65 0.324
guanosine containing compound catabolic process GO:1901069 144 0.298
positive regulation of gtpase activity GO:0043547 85 0.295
regulation of ras gtpase activity GO:0032318 88 0.272
regulation of ras protein signal transduction GO:0046578 114 0.262
organonitrogen compound catabolic process GO:1901565 264 0.252
organic cyclic compound catabolic process GO:1901361 295 0.252
guanosine containing compound metabolic process GO:1901068 144 0.238
ribonucleoside triphosphate catabolic process GO:0009203 199 0.231
gtp metabolic process GO:0046039 144 0.218
heterocycle catabolic process GO:0046700 280 0.215
regulation of gtp catabolic process GO:0033124 113 0.215
glycosyl compound catabolic process GO:1901658 206 0.215
positive regulation of nucleoside metabolic process GO:0045979 91 0.213
nucleoside phosphate metabolic process GO:0006753 338 0.213
purine nucleotide catabolic process GO:0006195 211 0.204
ribonucleoside metabolic process GO:0009119 245 0.204
positive regulation of gtp catabolic process GO:0033126 85 0.195
nucleoside catabolic process GO:0009164 206 0.194
aromatic compound catabolic process GO:0019439 286 0.182
ribonucleoside triphosphate metabolic process GO:0009199 220 0.180
organophosphate catabolic process GO:0046434 232 0.175
purine nucleoside triphosphate catabolic process GO:0009146 203 0.175
ribonucleoside catabolic process GO:0042454 206 0.173
purine ribonucleotide catabolic process GO:0009154 208 0.173
regulation of nucleoside metabolic process GO:0009118 130 0.173
nucleotide metabolic process GO:0009117 332 0.172
cellular nitrogen compound catabolic process GO:0044270 280 0.166
purine nucleotide metabolic process GO:0006163 302 0.164
purine nucleoside metabolic process GO:0042278 241 0.164
nucleoside metabolic process GO:0009116 246 0.163
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.160
gtp catabolic process GO:0006184 143 0.154
purine ribonucleoside metabolic process GO:0046128 241 0.154
glycosyl compound metabolic process GO:1901657 246 0.153
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.153
purine nucleoside catabolic process GO:0006152 205 0.151
nucleobase containing small molecule metabolic process GO:0055086 352 0.148
regulation of purine nucleotide catabolic process GO:0033121 122 0.146
purine ribonucleotide metabolic process GO:0009150 290 0.144
regulation of hydrolase activity GO:0051336 246 0.143
nucleotide catabolic process GO:0009166 217 0.138
positive regulation of nucleotide catabolic process GO:0030813 88 0.137
ribose phosphate metabolic process GO:0019693 291 0.136
nucleoside triphosphate metabolic process GO:0009141 230 0.134
carbohydrate derivative catabolic process GO:1901136 231 0.131
ribonucleotide metabolic process GO:0009259 291 0.131
regulation of cellular catabolic process GO:0031329 242 0.127
rho protein signal transduction GO:0007266 32 0.126
purine containing compound metabolic process GO:0072521 311 0.120
regulation of cellular amino acid metabolic process GO:0006521 5 0.119
purine nucleoside triphosphate metabolic process GO:0009144 226 0.119
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.119
purine ribonucleoside catabolic process GO:0046130 205 0.118
ribonucleotide catabolic process GO:0009261 208 0.117
purine containing compound catabolic process GO:0072523 213 0.115
nucleoside phosphate catabolic process GO:1901292 222 0.108
cellular ketone metabolic process GO:0042180 84 0.105
nucleoside triphosphate catabolic process GO:0009143 205 0.104
amine metabolic process GO:0009308 45 0.104
cellular amino acid metabolic process GO:0006520 103 0.100
positive regulation of nucleotide metabolic process GO:0045981 114 0.098
positive regulation of hydrolase activity GO:0051345 148 0.098
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.091
regulation of nucleotide metabolic process GO:0006140 169 0.089
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.088
synaptic transmission GO:0007268 329 0.083
regulation of cellular amine metabolic process GO:0033238 20 0.083
cellular amine metabolic process GO:0044106 44 0.082
regulation of nucleotide catabolic process GO:0030811 122 0.081
regulation of transferase activity GO:0051338 263 0.080
membrane organization GO:0061024 245 0.077
regulation of neuron differentiation GO:0045664 281 0.074
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.074
positive regulation of cellular amine metabolic process GO:0033240 5 0.072
regulation of purine nucleotide metabolic process GO:1900542 169 0.071
regulation of cell projection organization GO:0031344 206 0.070
regulation of rho gtpase activity GO:0032319 58 0.067
negative regulation of protein metabolic process GO:0051248 282 0.067
ion transmembrane transport GO:0034220 361 0.066
regulation of cellular ketone metabolic process GO:0010565 66 0.066
negative regulation of cellular protein metabolic process GO:0032269 247 0.065
regulation of protein kinase activity GO:0045859 232 0.065
response to insulin GO:0032868 100 0.064
axonogenesis GO:0007409 274 0.063
cellular response to organonitrogen compound GO:0071417 145 0.063
macromolecule catabolic process GO:0009057 281 0.062
negative regulation of cellular amine metabolic process GO:0033239 1 0.062
rab protein signal transduction GO:0032482 1 0.061
mapk cascade GO:0000165 281 0.060
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
endomembrane system organization GO:0010256 147 0.058
positive regulation of rho gtpase activity GO:0032321 41 0.057
response to organonitrogen compound GO:0010243 246 0.056
actin cytoskeleton organization GO:0030036 220 0.056
organelle assembly GO:0070925 177 0.055
cellular lipid metabolic process GO:0044255 323 0.054
regulation of mapk cascade GO:0043408 248 0.051
positive regulation of organelle organization GO:0010638 128 0.050
regulation of cellular component biogenesis GO:0044087 181 0.050
exocytosis GO:0006887 121 0.050
protein localization to membrane GO:0072657 108 0.050
negative regulation of phosphorylation GO:0042326 166 0.049
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.049
germ cell development GO:0007281 185 0.049
microtubule based process GO:0007017 236 0.048
response to peptide hormone GO:0043434 127 0.048
negative regulation of intracellular signal transduction GO:1902532 167 0.048
Rat
dephosphorylation GO:0016311 129 0.048
Rat Fly
regulation of organelle organization GO:0033043 289 0.047
positive regulation of protein phosphorylation GO:0001934 242 0.046
forebrain development GO:0030900 302 0.046
Rat
regulation of kinase activity GO:0043549 249 0.045
regulation of cellular response to stress GO:0080135 159 0.045
embryonic epithelial tube formation GO:0001838 130 0.045
regulation of cell activation GO:0050865 289 0.044
transmembrane transport GO:0055085 412 0.044
cellular protein complex assembly GO:0043623 116 0.044
regulation of cellular component size GO:0032535 121 0.044
regulation of neuron projection development GO:0010975 169 0.044
regulation of t cell activation GO:0050863 170 0.043
synapse organization GO:0050808 125 0.043
positive regulation of protein modification process GO:0031401 299 0.043
negative regulation of cellular component organization GO:0051129 194 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.043
response to oxidative stress GO:0006979 123 0.042
regulation of anatomical structure size GO:0090066 178 0.042
muscle cell differentiation GO:0042692 261 0.042
regulation of cell cycle GO:0051726 281 0.042
cation transport GO:0006812 399 0.042
positive regulation of nervous system development GO:0051962 221 0.042
t cell activation GO:0042110 289 0.041
cellular response to insulin stimulus GO:0032869 78 0.041
regulation of rho protein signal transduction GO:0035023 71 0.041
maintenance of location GO:0051235 89 0.041
establishment of organelle localization GO:0051656 122 0.040
cytokine production GO:0001816 319 0.040
response to growth factor GO:0070848 198 0.039
plasma membrane organization GO:0007009 90 0.039
regulation of cell motility GO:2000145 236 0.039
organelle localization GO:0051640 179 0.039
regionalization GO:0003002 337 0.039
cell adhesion GO:0007155 329 0.039
nitrogen compound transport GO:0071705 271 0.039
protein modification by small protein conjugation GO:0032446 187 0.038
regulation of membrane potential GO:0042391 192 0.038
negative regulation of cell proliferation GO:0008285 296 0.038
chemotaxis GO:0006935 247 0.038
multicellular organismal signaling GO:0035637 91 0.037
regulation of intracellular transport GO:0032386 159 0.037
modification dependent macromolecule catabolic process GO:0043632 133 0.037
neuronal action potential GO:0019228 54 0.037
positive regulation of transferase activity GO:0051347 167 0.037
peptidyl amino acid modification GO:0018193 336 0.037
positive regulation of cell development GO:0010720 237 0.036
positive regulation of kinase activity GO:0033674 155 0.036
regulation of response to wounding GO:1903034 189 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
regulation of protein localization GO:0032880 231 0.036
epithelial tube morphogenesis GO:0060562 303 0.036
positive regulation of programmed cell death GO:0043068 218 0.035
male gamete generation GO:0048232 285 0.035
olfactory learning GO:0008355 2 0.035
protein ubiquitination GO:0016567 171 0.035
regulation of vesicle mediated transport GO:0060627 139 0.035
cellular macromolecule catabolic process GO:0044265 206 0.034
cellular response to peptide GO:1901653 92 0.034
multicellular organism growth GO:0035264 161 0.034
regulation of actin filament polymerization GO:0030833 38 0.034
regulation of fatty acid beta oxidation GO:0031998 1 0.034
immune effector process GO:0002252 321 0.034
apoptotic signaling pathway GO:0097190 306 0.034
developmental growth involved in morphogenesis GO:0060560 138 0.034
oxidation reduction process GO:0055114 342 0.034
regulation of ion transmembrane transport GO:0034765 119 0.033
regulation of ral gtpase activity GO:0032315 4 0.033
regulation of response to drug GO:2001023 2 0.033
cognition GO:0050890 149 0.033
regulation of secretion by cell GO:1903530 249 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
cytoplasmic transport GO:0016482 234 0.033
action potential GO:0001508 78 0.032
response to radiation GO:0009314 165 0.032
cellular component assembly involved in morphogenesis GO:0010927 139 0.032
morphogenesis of embryonic epithelium GO:0016331 159 0.032
regulation of protein serine threonine kinase activity GO:0071900 157 0.032
protein catabolic process GO:0030163 221 0.032
negative regulation of synapse assembly GO:0051964 3 0.032
negative regulation of protein modification process GO:0031400 163 0.032
negative regulation of protein phosphorylation GO:0001933 126 0.031
positive regulation of protein kinase activity GO:0045860 144 0.031
regulation of cell migration GO:0030334 219 0.031
cellular response to growth factor stimulus GO:0071363 197 0.031
regulation of cytokine production GO:0001817 266 0.031
positive regulation of cell death GO:0010942 224 0.030
homeostasis of number of cells GO:0048872 210 0.030
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.030
response to peptide GO:1901652 136 0.030
regulation of secretion GO:0051046 274 0.030
lipid biosynthetic process GO:0008610 179 0.030
negative regulation of phosphate metabolic process GO:0045936 184 0.029
cellular response to peptide hormone stimulus GO:0071375 92 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.029
response to extracellular stimulus GO:0009991 127 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
actin polymerization or depolymerization GO:0008154 54 0.029
cell type specific apoptotic process GO:0097285 268 0.029
regulation of alpha beta t cell activation GO:0046634 53 0.029
regulation of transmembrane transport GO:0034762 128 0.029
myotube differentiation GO:0014902 105 0.028
b cell activation GO:0042113 161 0.028
negative regulation of cell projection organization GO:0031345 56 0.028
adaptive immune response GO:0002250 155 0.028
tube formation GO:0035148 140 0.028
leukocyte differentiation GO:0002521 342 0.028
inflammatory response GO:0006954 244 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
compound eye development GO:0048749 1 0.028
lymphocyte proliferation GO:0046651 164 0.027
protein polymerization GO:0051258 57 0.027
cellular carbohydrate metabolic process GO:0044262 119 0.027
intracellular protein transport GO:0006886 204 0.027
regulation of insulin receptor signaling pathway GO:0046626 21 0.027
fatty acid metabolic process GO:0006631 121 0.026
neural tube formation GO:0001841 108 0.026
epithelial tube formation GO:0072175 130 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
negative regulation of cell size GO:0045792 3 0.026
transmission of nerve impulse GO:0019226 76 0.026
actin filament polymerization GO:0030041 44 0.026
embryonic placenta development GO:0001892 98 0.026
regulation of cell size GO:0008361 72 0.026
learning or memory GO:0007611 148 0.025
retrograde transport endosome to golgi GO:0042147 2 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.025
myelination GO:0042552 74 0.025
regulation of ral protein signal transduction GO:0032485 4 0.025
negative regulation of nervous system development GO:0051961 156 0.025
dendrite development GO:0016358 115 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
epidermis development GO:0008544 187 0.024
endocytosis GO:0006897 168 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
regulation of defense response GO:0031347 233 0.024
regulation of t cell proliferation GO:0042129 92 0.024
microtubule based movement GO:0007018 84 0.024
cellular response to external stimulus GO:0071496 88 0.024
regulation of interleukin 10 secretion GO:2001179 4 0.024
cytokine biosynthetic process GO:0042089 68 0.024
placenta development GO:0001890 140 0.024
regulation of cytoskeleton organization GO:0051493 122 0.024
circulatory system process GO:0003013 197 0.024
protein localization to plasma membrane GO:0072659 57 0.024
rna 3 end processing GO:0031123 20 0.023
regulation of leukocyte differentiation GO:1902105 159 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
regulation of lipid metabolic process GO:0019216 118 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
negative regulation of kinase activity GO:0033673 81 0.023
response to nutrient levels GO:0031667 109 0.023
neural tube development GO:0021915 160 0.023
vesicle organization GO:0016050 60 0.023
sensory perception GO:0007600 245 0.023
glucose homeostasis GO:0042593 128 0.023
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.023
regulation of jnk cascade GO:0046328 62 0.023
positive regulation of secretion by cell GO:1903532 114 0.023
carbohydrate metabolic process GO:0005975 230 0.023
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.023
peptidyl serine phosphorylation GO:0018105 74 0.023
negative regulation of cell development GO:0010721 169 0.023
leukocyte proliferation GO:0070661 172 0.023
ensheathment of neurons GO:0007272 76 0.023
response to uv GO:0009411 44 0.022
innate immune response GO:0045087 157 0.022
lymphocyte mediated immunity GO:0002449 139 0.022
regulation of ion transport GO:0043269 215 0.022
oocyte axis specification GO:0007309 2 0.022
neural tube closure GO:0001843 90 0.022
camera type eye development GO:0043010 266 0.022
jnk cascade GO:0007254 72 0.022
leukocyte mediated immunity GO:0002443 174 0.022
response to organic cyclic compound GO:0014070 198 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
regulation of system process GO:0044057 200 0.022
peptidyl tyrosine modification GO:0018212 145 0.022
negative regulation of molecular function GO:0044092 258 0.022
positive regulation of cell activation GO:0050867 158 0.022
regulation of homeostatic process GO:0032844 182 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
regulation of hormone levels GO:0010817 211 0.021
oocyte construction GO:0007308 2 0.021
single organism cell adhesion GO:0098602 156 0.021
lipid localization GO:0010876 126 0.021
anion transport GO:0006820 177 0.021
vesicle localization GO:0051648 86 0.021
mitotic cell cycle GO:0000278 195 0.021
positive regulation of secretion GO:0051047 130 0.021
stress activated protein kinase signaling cascade GO:0031098 81 0.021
regulation of actin filament based process GO:0032970 99 0.021
lymphocyte differentiation GO:0030098 242 0.021
wnt signaling pathway GO:0016055 188 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
tube closure GO:0060606 91 0.021
regulation of protein catabolic process GO:0042176 108 0.021
fat cell differentiation GO:0045444 160 0.021
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.021
developmental cell growth GO:0048588 84 0.021
gland development GO:0048732 330 0.020
spermatogenesis GO:0007283 284 0.020
peptidyl threonine modification GO:0018210 31 0.020
telencephalon development GO:0021537 186 0.020
Rat
nucleocytoplasmic transport GO:0006913 139 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.020
actin filament organization GO:0007015 113 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
insulin receptor signaling pathway GO:0008286 49 0.020
mrna 3 end processing GO:0031124 16 0.020
positive regulation of interleukin 5 secretion GO:2000664 1 0.020
hindbrain development GO:0030902 128 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
cell recognition GO:0008037 83 0.020
t helper 2 cell cytokine production GO:0035745 4 0.020
rna processing GO:0006396 105 0.020
cation transmembrane transport GO:0098655 266 0.020
regulation of synaptic plasticity GO:0048167 87 0.020
phagocytosis GO:0006909 66 0.020
engulfment of apoptotic cell GO:0043652 3 0.020
t cell proliferation GO:0042098 120 0.020
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.019
monosaccharide transport GO:0015749 58 0.019
negative regulation of growth GO:0045926 99 0.019
regulation of lymphocyte proliferation GO:0050670 117 0.019
primary neural tube formation GO:0014020 95 0.019
amide transport GO:0042886 138 0.019
positive regulation of cell cycle GO:0045787 92 0.019
cellular protein catabolic process GO:0044257 155 0.019
spermatid differentiation GO:0048515 115 0.019
mrna metabolic process GO:0016071 84 0.019
digestive system development GO:0055123 200 0.019
response to lipopolysaccharide GO:0032496 128 0.019
circadian rhythm GO:0007623 114 0.019
establishment of vesicle localization GO:0051650 81 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
peptidyl serine modification GO:0018209 83 0.019
sequestering of metal ion GO:0051238 19 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
cellular chemical homeostasis GO:0055082 215 0.019
positive regulation of cell motility GO:2000147 116 0.019
rna catabolic process GO:0006401 29 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
ral protein signal transduction GO:0032484 2 0.018
positive regulation of leukocyte proliferation GO:0070665 73 0.018
regulation of protein complex assembly GO:0043254 83 0.018
lateral inhibition GO:0046331 1 0.018
protein targeting GO:0006605 143 0.018
dna metabolic process GO:0006259 303 0.018
regulation of proteolysis GO:0030162 164 0.018
regulation of metal ion transport GO:0010959 106 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
regulation of leukocyte mediated immunity GO:0002703 104 0.018
divalent metal ion transport GO:0070838 172 0.018
regulation of stress activated mapk cascade GO:0032872 69 0.018
regulation of cell shape GO:0008360 39 0.018
divalent inorganic cation transport GO:0072511 178 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
positive regulation of protein catabolic process GO:0045732 60 0.018
axon ensheathment GO:0008366 76 0.018
regulation of feeding behavior GO:0060259 3 0.018
female gamete generation GO:0007292 74 0.018
pole plasm assembly GO:0007315 2 0.018
peptidyl tyrosine phosphorylation GO:0018108 143 0.018
positive regulation of cell projection organization GO:0031346 95 0.018
stress activated mapk cascade GO:0051403 80 0.018
g1 s transition of mitotic cell cycle GO:0000082 57 0.017
regulation of actin filament length GO:0030832 45 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
cellular response to nutrient levels GO:0031669 64 0.017
ossification GO:0001503 216 0.017
epithelial cell development GO:0002064 159 0.017
cell activation involved in immune response GO:0002263 126 0.017
carbohydrate transport GO:0008643 62 0.017
defense response to other organism GO:0098542 197 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
negative regulation of cell activation GO:0050866 111 0.017
leukocyte apoptotic process GO:0071887 71 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
ameboidal type cell migration GO:0001667 128 0.017
peptidyl threonine phosphorylation GO:0018107 31 0.017
labyrinthine layer development GO:0060711 49 0.017
negative regulation of organelle organization GO:0010639 90 0.017
regulation of t helper 2 cell cytokine production GO:2000551 3 0.017
regulation of protein transport GO:0051223 163 0.017
hexose metabolic process GO:0019318 98 0.017
glial cell differentiation GO:0010001 131 0.017
defense response to bacterium GO:0042742 119 0.017
glucose transport GO:0015758 56 0.017
axon guidance GO:0007411 141 0.017
positive regulation of alpha beta t cell activation GO:0046635 39 0.017
response to light stimulus GO:0009416 135 0.017
monosaccharide metabolic process GO:0005996 106 0.017
response to epidermal growth factor GO:0070849 4 0.017
regulation of neuron death GO:1901214 134 0.017
t cell differentiation GO:0030217 174 0.017
cell division GO:0051301 120 0.017
positive regulation of t cell activation GO:0050870 101 0.017
syncytium formation by plasma membrane fusion GO:0000768 42 0.016
cellular homeostasis GO:0019725 240 0.016
regulation of actin polymerization or depolymerization GO:0008064 45 0.016
protein localization to organelle GO:0033365 185 0.016
learning GO:0007612 98 0.016
sensory organ morphogenesis GO:0090596 242 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
regulation of cytokine biosynthetic process GO:0042035 59 0.016
stem cell differentiation GO:0048863 268 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.016
blood coagulation GO:0007596 76 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
positive regulation of proteolysis GO:0045862 85 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
blood circulation GO:0008015 195 0.016
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.016
asymmetric stem cell division GO:0098722 3 0.016
epithelial cell proliferation GO:0050673 174 0.016
spermatid development GO:0007286 108 0.016
stem cell development GO:0048864 219 0.016
energy derivation by oxidation of organic compounds GO:0015980 77 0.016
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.016
regulation of t cell differentiation GO:0045580 83 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
rap protein signal transduction GO:0032486 3 0.016
organelle fusion GO:0048284 28 0.016
muscle system process GO:0003012 141 0.016
translation GO:0006412 93 0.016
interleukin 10 secretion GO:0072608 4 0.016
actomyosin structure organization GO:0031032 56 0.016
mitochondrion transport along microtubule GO:0047497 3 0.016
carbon catabolite activation of transcription GO:0045991 4 0.016
cell fate commitment GO:0045165 210 0.016
development of primary sexual characteristics GO:0045137 143 0.016
blood vessel morphogenesis GO:0048514 285 0.016
muscle cell development GO:0055001 133 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
protein maturation GO:0051604 176 0.015
regulation of map kinase activity GO:0043405 120 0.015
positive regulation of growth GO:0045927 104 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
positive regulation of immune effector process GO:0002699 107 0.015
sequestering of calcium ion GO:0051208 18 0.015
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.015
locomotory behavior GO:0007626 195 0.015
positive regulation of cytokine production GO:0001819 174 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
negative regulation of transferase activity GO:0051348 85 0.015
negative regulation of cell cycle GO:0045786 123 0.015
glycerolipid metabolic process GO:0046486 122 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
sensory perception of sound GO:0007605 97 0.015
wound healing GO:0042060 157 0.015
regulation of binding GO:0051098 111 0.015
mitochondrion organization GO:0007005 134 0.015
response to oxygen levels GO:0070482 62 0.015
muscle tissue development GO:0060537 308 0.015
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.015
mitotic cell cycle process GO:1903047 159 0.015
chromatin organization GO:0006325 206 0.015
organic acid transport GO:0015849 101 0.015
carboxylic acid transport GO:0046942 100 0.015
mrna processing GO:0006397 63 0.015
negative regulation of protein processing GO:0010955 79 0.014
gliogenesis GO:0042063 141 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
organelle fission GO:0048285 170 0.014
cytoskeleton dependent intracellular transport GO:0030705 50 0.014

Phlpp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.043
disease of cellular proliferation DOID:14566 0 0.043
organ system cancer DOID:0050686 0 0.043
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
central nervous system disease DOID:331 0 0.022
immune system disease DOID:2914 0 0.021
bone disease DOID:0080001 0 0.017
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.017