Mus musculus

89 known processes

Pias2

protein inhibitor of activated STAT 2

(Aliases: AI462206,Miz1,SIZ2,AU018068,PIASxalpha,ARIP3,Dib,6330408K17Rik,PIASxb,PIASxbeta)

Pias2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ubiquitin dependent protein catabolic process GO:0006511 129 0.631
Mouse
modification dependent macromolecule catabolic process GO:0043632 133 0.630
Mouse
cellular protein catabolic process GO:0044257 155 0.539
Mouse
proteasomal protein catabolic process GO:0010498 98 0.475
Mouse
intracellular protein transport GO:0006886 204 0.339
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.320
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.299
Mouse
positive regulation of proteolysis GO:0045862 85 0.297
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.296
negative regulation of protein metabolic process GO:0051248 282 0.284
macromolecule catabolic process GO:0009057 281 0.269
Mouse
modification dependent protein catabolic process GO:0019941 133 0.265
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.241
Mouse
negative regulation of phosphorylation GO:0042326 166 0.225
negative regulation of protein modification process GO:0031400 163 0.221
cytoplasmic transport GO:0016482 234 0.220
negative regulation of protein phosphorylation GO:0001933 126 0.200
protein catabolic process GO:0030163 221 0.200
Mouse
wnt signaling pathway GO:0016055 188 0.196
response to radiation GO:0009314 165 0.192
cellular ketone metabolic process GO:0042180 84 0.190
negative regulation of phosphate metabolic process GO:0045936 184 0.180
negative regulation of phosphorus metabolic process GO:0010563 184 0.164
negative regulation of kinase activity GO:0033673 81 0.157
protein modification by small protein conjugation or removal GO:0070647 207 0.151
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.145
protein ubiquitination GO:0016567 171 0.136
membrane organization GO:0061024 245 0.134
negative regulation of wnt signaling pathway GO:0030178 73 0.132
cellular amine metabolic process GO:0044106 44 0.132
cellular response to growth factor stimulus GO:0071363 197 0.124
negative regulation of molecular function GO:0044092 258 0.123
Mouse
regulation of translation GO:0006417 71 0.122
regulation of establishment of protein localization GO:0070201 181 0.118
protein modification by small protein conjugation GO:0032446 187 0.118
negative regulation of cell proliferation GO:0008285 296 0.110
amine metabolic process GO:0009308 45 0.109
regulation of intracellular protein transport GO:0033157 82 0.104
regulation of proteolysis GO:0030162 164 0.100
Mouse
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.099
Mouse
negative regulation of transferase activity GO:0051348 85 0.098
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.098
Mouse
cellular response to gamma radiation GO:0071480 4 0.096
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.096
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.092
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.092
rna processing GO:0006396 105 0.090
bmp signaling pathway GO:0030509 93 0.088
regulation of cellular amino acid metabolic process GO:0006521 5 0.088
regulation of cellular protein catabolic process GO:1903362 61 0.086
Mouse
response to growth factor GO:0070848 198 0.082
nucleocytoplasmic transport GO:0006913 139 0.078
protein localization to organelle GO:0033365 185 0.078
regulation of proteasomal protein catabolic process GO:0061136 46 0.076
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.074
regulation of wnt signaling pathway GO:0030111 123 0.073
positive regulation of cellular catabolic process GO:0031331 148 0.072
Mouse
cellular chemical homeostasis GO:0055082 215 0.072
intrinsic apoptotic signaling pathway GO:0097193 132 0.070
Mouse
locomotory behavior GO:0007626 195 0.070
adrenal cortex development GO:0035801 2 0.070
negative regulation of cellular amine metabolic process GO:0033239 1 0.069
positive regulation of cellular protein catabolic process GO:1903364 34 0.067
Mouse
rna 3 end processing GO:0031123 20 0.067
regionalization GO:0003002 337 0.066
fat cell differentiation GO:0045444 160 0.065
regulation of protein catabolic process GO:0042176 108 0.062
Mouse
nuclear transport GO:0051169 139 0.061
regulation of cellular ketone metabolic process GO:0010565 66 0.061
positive regulation of protein catabolic process GO:0045732 60 0.061
Mouse
regulation of kinase activity GO:0043549 249 0.061
negative regulation of multi organism process GO:0043901 68 0.060
mitotic cell cycle process GO:1903047 159 0.060
Fly
regulation of cell cycle GO:0051726 281 0.059
Fly
endocytosis GO:0006897 168 0.059
cellular homeostasis GO:0019725 240 0.057
posttranscriptional regulation of gene expression GO:0010608 155 0.056
regulation of membrane potential GO:0042391 192 0.056
cellular amino acid metabolic process GO:0006520 103 0.054
endomembrane system organization GO:0010256 147 0.053
regulation of intracellular transport GO:0032386 159 0.053
learning or memory GO:0007611 148 0.052
negative regulation of ovulation GO:0060280 1 0.051
regulation of protein kinase activity GO:0045859 232 0.050
apoptotic signaling pathway GO:0097190 306 0.050
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.049
Mouse
stem cell differentiation GO:0048863 268 0.048
response to extracellular stimulus GO:0009991 127 0.048
peptidyl amino acid modification GO:0018193 336 0.047
chromatin modification GO:0016568 187 0.047
regulation of cytoplasmic transport GO:1903649 112 0.046
cognition GO:0050890 149 0.046
regulation of cell motility GO:2000145 236 0.046
cell growth GO:0016049 130 0.046
single fertilization GO:0007338 82 0.045
heterocycle catabolic process GO:0046700 280 0.044
organic cyclic compound catabolic process GO:1901361 295 0.042
regulation of cellular component size GO:0032535 121 0.042
cellular response to extracellular stimulus GO:0031668 81 0.042
positive regulation of cell development GO:0010720 237 0.041
establishment of protein localization to organelle GO:0072594 118 0.040
neuronal action potential GO:0019228 54 0.040
posterior mesonephric tubule development GO:0072166 2 0.039
regulation of protein localization GO:0032880 231 0.038
regulation of nucleocytoplasmic transport GO:0046822 73 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
response to oxidative stress GO:0006979 123 0.037
response to monosaccharide GO:0034284 67 0.036
positive regulation of programmed cell death GO:0043068 218 0.036
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
regulation of ovulation GO:0060278 3 0.035
positive regulation of cell migration GO:0030335 109 0.035
synaptic transmission GO:0007268 329 0.035
glycosyl compound catabolic process GO:1901658 206 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
histone modification GO:0016570 159 0.035
developmental maturation GO:0021700 193 0.034
axonogenesis GO:0007409 274 0.033
phagocytosis GO:0006909 66 0.033
leukocyte differentiation GO:0002521 342 0.033
epithelial tube morphogenesis GO:0060562 303 0.033
regulation of multi organism process GO:0043900 111 0.033
lymphocyte differentiation GO:0030098 242 0.032
covalent chromatin modification GO:0016569 163 0.032
negative regulation of map kinase activity GO:0043407 34 0.032
action potential GO:0001508 78 0.032
protein maturation GO:0051604 176 0.032
ensheathment of neurons GO:0007272 76 0.032
chemotaxis GO:0006935 247 0.031
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.031
regulation of protein targeting GO:1903533 61 0.031
protein targeting GO:0006605 143 0.031
muscle cell differentiation GO:0042692 261 0.030
positive regulation of growth GO:0045927 104 0.030
Worm
response to transforming growth factor beta GO:0071559 88 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.030
renal system development GO:0072001 225 0.030
nuclear export GO:0051168 34 0.030
protein polyubiquitination GO:0000209 33 0.030
camera type eye development GO:0043010 266 0.030
regulation of canonical wnt signaling pathway GO:0060828 82 0.030
regulation of cell migration GO:0030334 219 0.029
negative regulation of cell cycle GO:0045786 123 0.029
Fly
skeletal muscle organ development GO:0060538 163 0.029
regulation of ossification GO:0030278 112 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
response to nutrient levels GO:0031667 109 0.029
cell type specific apoptotic process GO:0097285 268 0.029
Mouse
regulation of transferase activity GO:0051338 263 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
nucleotide metabolic process GO:0009117 332 0.029
negative regulation of growth GO:0045926 99 0.028
multi multicellular organism process GO:0044706 109 0.028
regulation of protein transport GO:0051223 163 0.028
telencephalon development GO:0021537 186 0.028
regulation of protein localization to nucleus GO:1900180 60 0.028
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.028
muscle tissue development GO:0060537 308 0.028
organ growth GO:0035265 117 0.028
dna metabolic process GO:0006259 303 0.028
Fly
cellular response to dna damage stimulus GO:0006974 207 0.028
Mouse Worm Fly
regulation of homeostatic process GO:0032844 182 0.028
skeletal system development GO:0001501 356 0.027
cellular response to external stimulus GO:0071496 88 0.027
regulation of chromosome organization GO:0033044 83 0.027
response to inorganic substance GO:0010035 96 0.027
negative regulation of immune system process GO:0002683 209 0.027
carbohydrate homeostasis GO:0033500 128 0.027
response to peptide hormone GO:0043434 127 0.027
fertilization GO:0009566 127 0.027
single organism nuclear import GO:1902593 95 0.026
oocyte maturation GO:0001556 18 0.026
sperm motility GO:0030317 47 0.026
morphogenesis of a branching epithelium GO:0061138 193 0.026
cation transmembrane transport GO:0098655 266 0.025
cellular component assembly involved in morphogenesis GO:0010927 139 0.025
regulation of cell activation GO:0050865 289 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
connective tissue development GO:0061448 179 0.025
positive regulation of cell motility GO:2000147 116 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
anatomical structure homeostasis GO:0060249 145 0.025
stem cell development GO:0048864 219 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
cofactor transport GO:0051181 4 0.024
stem cell proliferation GO:0072089 117 0.024
nucleoside metabolic process GO:0009116 246 0.024
regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900211 4 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.024
Mouse
transmembrane transport GO:0055085 412 0.024
urogenital system development GO:0001655 261 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
regulation of protein ubiquitination GO:0031396 52 0.024
glucose homeostasis GO:0042593 128 0.024
neural tube development GO:0021915 160 0.024
purine containing compound metabolic process GO:0072521 311 0.024
t cell activation GO:0042110 289 0.024
blood vessel morphogenesis GO:0048514 285 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
morphogenesis of embryonic epithelium GO:0016331 159 0.023
angiogenesis GO:0001525 201 0.023
cell division GO:0051301 120 0.023
carbohydrate metabolic process GO:0005975 230 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
response to organonitrogen compound GO:0010243 246 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
adrenal cortex formation GO:0035802 2 0.023
positive regulation of protein modification process GO:0031401 299 0.023
positive regulation of protein oligomerization GO:0032461 4 0.023
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.022
protein homooligomerization GO:0051260 43 0.022
cation transport GO:0006812 399 0.022
positive regulation of dna templated transcription elongation GO:0032786 2 0.022
protein localization to plasma membrane GO:0072659 57 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
response to insulin GO:0032868 100 0.022
gland development GO:0048732 330 0.022
protein localization to membrane GO:0072657 108 0.022
transmission of nerve impulse GO:0019226 76 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.021
Mouse
endocrine system development GO:0035270 98 0.021
female gamete generation GO:0007292 74 0.021
positive regulation of nucleoside metabolic process GO:0045979 91 0.021
negative regulation of translation GO:0017148 22 0.021
regulation of ion transmembrane transport GO:0034765 119 0.021
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
organelle localization GO:0051640 179 0.021
gastrulation GO:0007369 116 0.021
cellular response to abiotic stimulus GO:0071214 56 0.021
multicellular organismal signaling GO:0035637 91 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
protein import GO:0017038 101 0.020
ion transmembrane transport GO:0034220 361 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
forebrain development GO:0030900 302 0.020
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.020
neuron projection guidance GO:0097485 141 0.020
regulation of cell division GO:0051302 76 0.020
oogenesis GO:0048477 56 0.020
regulation of t cell activation GO:0050863 170 0.020
positive regulation of protein complex assembly GO:0031334 45 0.020
gonad development GO:0008406 141 0.020
Worm
axon ensheathment GO:0008366 76 0.020
mesenchyme development GO:0060485 152 0.020
response to light stimulus GO:0009416 135 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
myelination GO:0042552 74 0.020
t cell differentiation GO:0030217 174 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
gliogenesis GO:0042063 141 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
protein processing GO:0016485 163 0.020
cellular response to radiation GO:0071478 28 0.020
segmentation GO:0035282 93 0.020
divalent inorganic cation transport GO:0072511 178 0.019
development of primary sexual characteristics GO:0045137 143 0.019
Worm
plasma membrane organization GO:0007009 90 0.019
adult behavior GO:0030534 135 0.019
regulation of neuron differentiation GO:0045664 281 0.019
cellularization GO:0007349 1 0.019
spermatogenesis GO:0007283 284 0.019
embryonic epithelial tube formation GO:0001838 130 0.019
visceral serous pericardium development GO:0061032 2 0.019
cellular response to lipid GO:0071396 145 0.019
olfactory learning GO:0008355 2 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
rhombomere 3 morphogenesis GO:0021658 2 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
male gonad development GO:0008584 88 0.018
organelle assembly GO:0070925 177 0.018
lateral inhibition GO:0046331 1 0.018
regulation of cellular response to growth factor stimulus GO:0090287 82 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
negative regulation of neuron death GO:1901215 98 0.018
regulation of ion transport GO:0043269 215 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
mitotic cell cycle GO:0000278 195 0.018
Fly
epithelial tube formation GO:0072175 130 0.018
neural precursor cell proliferation GO:0061351 121 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
cellular ion homeostasis GO:0006873 165 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
neuron death GO:0070997 154 0.017
synapse organization GO:0050808 125 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.017
regulation of transmembrane transport GO:0034762 128 0.017
positive regulation of intracellular transport GO:0032388 70 0.017
skeletal system morphogenesis GO:0048705 203 0.017
regulation of peptidase activity GO:0052547 96 0.017
striated muscle tissue development GO:0014706 293 0.017
skeletal muscle cell differentiation GO:0035914 66 0.017
hindbrain morphogenesis GO:0021575 46 0.017
protein oligomerization GO:0051259 67 0.017
germ cell development GO:0007281 185 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
respiratory system development GO:0060541 190 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
compound eye development GO:0048749 1 0.016
Fly
chromatin organization GO:0006325 206 0.016
cell fate commitment GO:0045165 210 0.016
pallium development GO:0021543 120 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
negative regulation of cell development GO:0010721 169 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
lipid biosynthetic process GO:0008610 179 0.016
tube formation GO:0035148 140 0.016
negative regulation of mapk cascade GO:0043409 65 0.016
cell maturation GO:0048469 127 0.016
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.016
Mouse
purine containing compound catabolic process GO:0072523 213 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
translation GO:0006412 93 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
mapk cascade GO:0000165 281 0.016
regulation of cellular response to stress GO:0080135 159 0.016
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.016
regulation of leukocyte differentiation GO:1902105 159 0.015
regulation of protein complex assembly GO:0043254 83 0.015
snrna processing GO:0016180 1 0.015
regulation of map kinase activity GO:0043405 120 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
regulation of endocytosis GO:0030100 69 0.015
negative regulation of phagocytosis GO:0050765 4 0.015
lipid localization GO:0010876 126 0.015
cofactor metabolic process GO:0051186 80 0.015
response to epidermal growth factor GO:0070849 4 0.015
organelle fission GO:0048285 170 0.015
development of primary male sexual characteristics GO:0046546 88 0.015
gene silencing by rna GO:0031047 19 0.015
oocyte axis specification GO:0007309 2 0.015
snrna metabolic process GO:0016073 1 0.015
rhythmic process GO:0048511 174 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
regulation of protein import into nucleus GO:0042306 52 0.015
regulation of system process GO:0044057 200 0.015
g1 s transition of mitotic cell cycle GO:0000082 57 0.015
nucleoside catabolic process GO:0009164 206 0.015
positive regulation of nervous system development GO:0051962 221 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
response to peptide GO:1901652 136 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
ossification GO:0001503 216 0.014
regulation of neuron death GO:1901214 134 0.014
nuclear import GO:0051170 95 0.014
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.014
innate immune response GO:0045087 157 0.014
Fly
positive regulation of cell cycle GO:0045787 92 0.014
digestive system development GO:0055123 200 0.014
Worm
immune effector process GO:0002252 321 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
positive regulation of steroid hormone secretion GO:2000833 2 0.014
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
maintenance of location GO:0051235 89 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
nucleotide catabolic process GO:0009166 217 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
bone morphogenesis GO:0060349 78 0.014
regulation of mapk cascade GO:0043408 248 0.014
cellular response to insulin stimulus GO:0032869 78 0.014
regulation of cell growth GO:0001558 91 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
cellular response to hexose stimulus GO:0071331 47 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
aromatic compound catabolic process GO:0019439 286 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
rna splicing GO:0008380 54 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
multi organism reproductive behavior GO:0044705 29 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
rhombomere 3 development GO:0021569 4 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
Fly
positive regulation of lymphocyte activation GO:0051251 140 0.013
regulation of secretion GO:0051046 274 0.013
protein acylation GO:0043543 64 0.013
tube closure GO:0060606 91 0.013
negative regulation of protein tyrosine kinase activity GO:0061099 3 0.013
organic anion transport GO:0015711 137 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
cell cycle switching GO:0060184 1 0.013
oxidation reduction process GO:0055114 342 0.013
regulation of cell cycle process GO:0010564 160 0.013
Fly
protein export from nucleus GO:0006611 20 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
monosaccharide metabolic process GO:0005996 106 0.012
cation homeostasis GO:0055080 212 0.012
bone development GO:0060348 120 0.012
protein localization to nucleus GO:0034504 121 0.012
neural tube formation GO:0001841 108 0.012
camp catabolic process GO:0006198 4 0.012
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.012
cytokine production GO:0001816 319 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.012
blood circulation GO:0008015 195 0.012
cyclic nucleotide metabolic process GO:0009187 59 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.012
rhombomere 5 formation GO:0021666 1 0.012
response to organic cyclic compound GO:0014070 198 0.012
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.012
organophosphate catabolic process GO:0046434 232 0.012
schwann cell differentiation GO:0014037 26 0.012
male sex differentiation GO:0046661 109 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.012
Mouse
mesonephros development GO:0001823 97 0.012
early endosome to late endosome transport GO:0045022 2 0.012
positive regulation of cell activation GO:0050867 158 0.012
positive regulation of chromosome segregation GO:0051984 4 0.012
positive regulation of nfat protein import into nucleus GO:0051533 1 0.012
positive regulation of t cell activation GO:0050870 101 0.012
negative regulation of leukocyte differentiation GO:1902106 51 0.012
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
Fly
hindbrain development GO:0030902 128 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
circulatory system process GO:0003013 197 0.012
regulation of cytokine production GO:0001817 266 0.012
regulation of organ formation GO:0003156 34 0.012
b cell activation GO:0042113 161 0.012
positive regulation of protein localization to nucleus GO:1900182 30 0.012
regulation of organ growth GO:0046620 61 0.011
feeding behavior GO:0007631 62 0.011
negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 4 0.011
multicellular organism growth GO:0035264 161 0.011
Worm
positive regulation of t cell differentiation in thymus GO:0033089 13 0.011
neuron apoptotic process GO:0051402 142 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
regulation of smoothened signaling pathway GO:0008589 58 0.011
regulation of organelle organization GO:0033043 289 0.011
renal tubule morphogenesis GO:0061333 72 0.011
regulation of transcription factor import into nucleus GO:0042990 24 0.011
regulation of neural precursor cell proliferation GO:2000177 70 0.011
actin cytoskeleton organization GO:0030036 220 0.011
neural tube closure GO:0001843 90 0.011
metal ion homeostasis GO:0055065 189 0.011
histone acetylation GO:0016573 41 0.011
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.011
dephosphorylation GO:0016311 129 0.011
regulation of response to wounding GO:1903034 189 0.011
mesonephric tubule development GO:0072164 94 0.011
positive regulation of lymphocyte differentiation GO:0045621 61 0.011
positive regulation of endocytosis GO:0045807 42 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
response to uv GO:0009411 44 0.011
negative regulation of nervous system development GO:0051961 156 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.011
regulation of hydrolase activity GO:0051336 246 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
striated muscle cell development GO:0055002 125 0.011
cofactor biosynthetic process GO:0051188 41 0.011
metencephalon development GO:0022037 89 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
response to hydrogen peroxide GO:0042542 32 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
cellular glucose homeostasis GO:0001678 52 0.011
regulation of fibroblast proliferation GO:0048145 34 0.011
negative regulation of metanephric glomerular mesangial cell proliferation GO:0072302 1 0.011
snrna 3 end processing GO:0034472 1 0.011
anion transport GO:0006820 177 0.011
regulation of protein processing GO:0070613 96 0.011
positive regulation of innate immune response GO:0045089 80 0.011
Fly
calcium ion transport GO:0006816 159 0.011
rhombomere 5 development GO:0021571 4 0.011
digestive tract morphogenesis GO:0048546 147 0.010
protein import into nucleus GO:0006606 95 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
Mouse
oocyte construction GO:0007308 2 0.010
metanephric part of ureteric bud development GO:0035502 2 0.010
reproductive behavior GO:0019098 32 0.010
g protein coupled receptor signaling pathway GO:0007186 243 0.010
homeostasis of number of cells GO:0048872 210 0.010
glucose metabolic process GO:0006006 92 0.010
viral transcription GO:0019083 3 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010

Pias2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.115
nervous system disease DOID:863 0 0.115
cancer DOID:162 0 0.047
disease of cellular proliferation DOID:14566 0 0.047
organ system cancer DOID:0050686 0 0.047
neuropathy DOID:870 0 0.024
large intestine cancer DOID:5672 0 0.017
colon cancer DOID:219 0 0.017
gastrointestinal system cancer DOID:3119 0 0.017
intestinal cancer DOID:10155 0 0.017
colorectal cancer DOID:9256 0 0.017
neuromuscular disease DOID:440 0 0.015
musculoskeletal system disease DOID:17 0 0.012