Mus musculus

38 known processes

Pik3cg

phosphoinositide-3-kinase, catalytic, gamma polypeptide

(Aliases: p110gamma,PI3Kgamma,5830428L06Rik)

Pik3cg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of inflammatory response GO:0050727 147 0.846
regulation of mast cell activation GO:0033003 21 0.832
activation of immune response GO:0002253 138 0.759
negative regulation of immune system process GO:0002683 209 0.699
regulation of defense response GO:0031347 233 0.662
cation transport GO:0006812 399 0.649
Mouse
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.615
immune response regulating signaling pathway GO:0002764 125 0.595
cytokine production GO:0001816 319 0.552
inflammatory response GO:0006954 244 0.526
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.525
regulation of lymphocyte proliferation GO:0050670 117 0.519
regulation of cell activation GO:0050865 289 0.512
regulation of exocytosis GO:0017157 61 0.506
calcium mediated signaling GO:0019722 46 0.503
regulation of ion transport GO:0043269 215 0.497
Mouse
leukocyte mediated immunity GO:0002443 174 0.497
divalent inorganic cation transport GO:0072511 178 0.493
t cell activation GO:0042110 289 0.491
immune effector process GO:0002252 321 0.482
g protein coupled receptor signaling pathway GO:0007186 243 0.444
positive regulation of cell activation GO:0050867 158 0.442
mapk cascade GO:0000165 281 0.440
leukocyte degranulation GO:0043299 27 0.429
leukocyte differentiation GO:0002521 342 0.416
regulation of leukocyte differentiation GO:1902105 159 0.406
regulation of vesicle mediated transport GO:0060627 139 0.400
myeloid leukocyte activation GO:0002274 83 0.396
positive regulation of phagocytosis GO:0050766 26 0.395
cation homeostasis GO:0055080 212 0.385
Mouse
divalent metal ion transport GO:0070838 172 0.373
calcium ion homeostasis GO:0055074 127 0.363
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.340
regulation of body fluid levels GO:0050878 162 0.334
Mouse
regulation of anatomical structure size GO:0090066 178 0.314
antigen receptor mediated signaling pathway GO:0050851 64 0.294
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.294
regulation of protein serine threonine kinase activity GO:0071900 157 0.293
negative regulation of leukocyte mediated immunity GO:0002704 29 0.290
regulation of leukocyte proliferation GO:0070663 121 0.282
regulation of cytokine production GO:0001817 266 0.279
regulation of innate immune response GO:0045088 91 0.277
coagulation GO:0050817 78 0.274
Mouse
serotonin secretion involved in inflammatory response GO:0002442 4 0.261
calcium ion transport GO:0006816 159 0.259
eosinophil activation GO:0043307 1 0.259
immune response activating signal transduction GO:0002757 116 0.258
positive regulation of t cell costimulation GO:2000525 2 0.258
regulation of t cell proliferation GO:0042129 92 0.253
cytoplasmic transport GO:0016482 234 0.251
negative regulation of homeostatic process GO:0032845 71 0.247
leukocyte migration GO:0050900 124 0.247
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.245
hemostasis GO:0007599 78 0.239
Mouse
cellular metal ion homeostasis GO:0006875 151 0.237
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.236
Mouse
positive regulation of cytokine production GO:0001819 174 0.234
regulation of leukocyte mediated immunity GO:0002703 104 0.222
organelle localization GO:0051640 179 0.217
regulated secretory pathway GO:0045055 32 0.216
leukocyte activation involved in immune response GO:0002366 126 0.212
sequestering of metal ion GO:0051238 19 0.209
regulation of response to wounding GO:1903034 189 0.208
divalent inorganic cation homeostasis GO:0072507 138 0.204
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.203
regulation of lymphocyte activation GO:0051249 240 0.202
regulation of homeostatic process GO:0032844 182 0.200
rho protein signal transduction GO:0007266 32 0.199
defense response to other organism GO:0098542 197 0.197
release of sequestered calcium ion into cytosol GO:0051209 42 0.197
alpha beta t cell activation GO:0046631 91 0.192
small gtpase mediated signal transduction GO:0007264 97 0.188
positive regulation of defense response GO:0031349 124 0.188
leukocyte proliferation GO:0070661 172 0.183
negative regulation of immune effector process GO:0002698 55 0.182
negative regulation of lymphocyte proliferation GO:0050672 45 0.175
t cell receptor signaling pathway GO:0050852 46 0.174
branching morphogenesis of an epithelial tube GO:0048754 159 0.173
myeloid leukocyte differentiation GO:0002573 119 0.173
positive regulation of t cell extravasation GO:2000409 2 0.173
regulation of secretion GO:0051046 274 0.172
regulation of kinase activity GO:0043549 249 0.170
Mouse
cytokine biosynthetic process GO:0042089 68 0.168
regulation of metal ion transport GO:0010959 106 0.167
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.167
positive regulation of gtp catabolic process GO:0033126 85 0.166
cellular lipid metabolic process GO:0044255 323 0.162
Mouse
regulation of calcium ion transport GO:0051924 69 0.161
cell chemotaxis GO:0060326 81 0.160
positive regulation of t cell activation GO:0050870 101 0.159
adaptive immune response GO:0002250 155 0.159
morphogenesis of a branching structure GO:0001763 203 0.157
lipid phosphorylation GO:0046834 25 0.157
Mouse
ras protein signal transduction GO:0007265 77 0.156
purine nucleoside triphosphate metabolic process GO:0009144 226 0.156
positive regulation of monocyte extravasation GO:2000439 1 0.154
serotonin production involved in inflammatory response GO:0002351 4 0.152
muscle system process GO:0003012 141 0.148
cellular calcium ion homeostasis GO:0006874 119 0.147
Mouse
positive regulation of cell motility GO:2000147 116 0.146
lymphocyte proliferation GO:0046651 164 0.145
hematopoietic stem cell migration GO:0035701 1 0.143
regulation of adaptive immune response GO:0002819 90 0.142
regulation of lymphocyte mediated immunity GO:0002706 84 0.142
regulation of hematopoietic stem cell migration GO:2000471 1 0.140
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.139
endocytosis GO:0006897 168 0.137
negative regulation of t cell proliferation GO:0042130 38 0.134
regulation of cell motility GO:2000145 236 0.133
regulation of mapk cascade GO:0043408 248 0.133
regulation of tumor necrosis factor production GO:0032680 49 0.131
regulation of phagocytosis GO:0050764 33 0.130
neutrophil chemotaxis GO:0030593 36 0.129
inflammatory response to antigenic stimulus GO:0002437 30 0.127
glycerophospholipid metabolic process GO:0006650 71 0.126
Mouse
regulation of hypersensitivity GO:0002883 10 0.124
regulation of secretion by cell GO:1903530 249 0.124
regulation of ion homeostasis GO:2000021 64 0.122
regulation of t cell activation GO:0050863 170 0.122
granulocyte migration GO:0097530 43 0.121
membrane organization GO:0061024 245 0.119
cellular amino acid metabolic process GO:0006520 103 0.119
microglial cell activation involved in immune response GO:0002282 1 0.119
positive regulation of t cell proliferation GO:0042102 52 0.117
axonogenesis GO:0007409 274 0.117
blood coagulation GO:0007596 76 0.117
Mouse
negative regulation of adaptive immune response GO:0002820 25 0.116
regulation of leukocyte degranulation GO:0043300 20 0.116
myeloid cell differentiation GO:0030099 233 0.113
regulation of cell migration GO:0030334 219 0.112
regulation of transferase activity GO:0051338 263 0.112
Mouse
t cell proliferation GO:0042098 120 0.111
ribonucleotide catabolic process GO:0009261 208 0.111
positive regulation of lymphocyte activation GO:0051251 140 0.109
positive regulation of cell migration GO:0030335 109 0.108
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.108
phagocytosis GO:0006909 66 0.107
metal ion homeostasis GO:0055065 189 0.105
Mouse
positive regulation of immune effector process GO:0002699 107 0.105
regulation of interleukin 6 production GO:0032675 55 0.104
regulation of membrane potential GO:0042391 192 0.104
positive regulation of map kinase activity GO:0043406 84 0.103
monocyte extravasation GO:0035696 2 0.103
positive regulation of kinase activity GO:0033674 155 0.103
Mouse
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.102
regulation of intracellular transport GO:0032386 159 0.100
muscle cell differentiation GO:0042692 261 0.099
platelet activation GO:0030168 40 0.098
Mouse
placenta development GO:0001890 140 0.097
cell activation involved in immune response GO:0002263 126 0.096
regulation of protein transport GO:0051223 163 0.096
tumor necrosis factor biosynthetic process GO:0042533 10 0.095
nucleoside phosphate metabolic process GO:0006753 338 0.094
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.093
exocytosis GO:0006887 121 0.093
regulation of monocyte extravasation GO:2000437 2 0.093
lysosome localization GO:0032418 20 0.092
cytokine secretion GO:0050663 72 0.092
cellular ion homeostasis GO:0006873 165 0.091
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.090
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.090
positive regulation of leukocyte mediated immunity GO:0002705 70 0.090
sequestering of calcium ion GO:0051208 18 0.090
helper t cell chemotaxis GO:0035704 1 0.089
ribonucleoside triphosphate catabolic process GO:0009203 199 0.089
second messenger mediated signaling GO:0019932 73 0.089
response to lipopolysaccharide GO:0032496 128 0.089
gastrulation GO:0007369 116 0.089
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.088
mast cell activation GO:0045576 27 0.088
regulation of purine nucleotide metabolic process GO:1900542 169 0.087
eosinophil degranulation GO:0043308 1 0.087
neuron apoptotic process GO:0051402 142 0.087
Mouse
neuronal action potential GO:0019228 54 0.086
myeloid cell activation involved in immune response GO:0002275 34 0.086
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.086
humoral immune response GO:0006959 57 0.086
positive regulation of leukocyte differentiation GO:1902107 86 0.085
regulation of t cell extravasation GO:2000407 3 0.085
positive regulation of tumor necrosis factor production GO:0032760 30 0.085
cytosolic calcium ion homeostasis GO:0051480 70 0.085
lymphocyte differentiation GO:0030098 242 0.084
immune complex clearance GO:0002434 2 0.084
positive regulation of inflammatory response GO:0050729 47 0.083
regulation of protein localization GO:0032880 231 0.083
negative regulation of cell activation GO:0050866 111 0.083
regulation of protein kinase activity GO:0045859 232 0.082
Mouse
erk1 and erk2 cascade GO:0070371 77 0.082
regulation of immunological synapse formation GO:2000520 2 0.082
positive regulation of homeostatic process GO:0032846 64 0.081
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.081
tumor necrosis factor production GO:0032640 50 0.080
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.080
regulation of b cell proliferation GO:0030888 39 0.080
positive regulation of intracellular transport GO:0032388 70 0.080
regulation of regulated secretory pathway GO:1903305 20 0.080
activation of mapk activity GO:0000187 59 0.080
reactive oxygen species metabolic process GO:0072593 84 0.079
positive regulation of nucleotide catabolic process GO:0030813 88 0.079
purine nucleotide catabolic process GO:0006195 211 0.079
chemotaxis GO:0006935 247 0.079
Worm
regulation of t cell costimulation GO:2000523 2 0.079
response to molecule of bacterial origin GO:0002237 143 0.078
sensory perception of pain GO:0019233 47 0.078
regulation of alpha beta t cell activation GO:0046634 53 0.077
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.076
regulation of mast cell degranulation GO:0043304 16 0.076
cellular response to cytokine stimulus GO:0071345 189 0.076
negative regulation of nik nf kappab signaling GO:1901223 2 0.076
regulation of organelle organization GO:0033043 289 0.076
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.076
hematopoietic progenitor cell differentiation GO:0002244 143 0.075
carbohydrate derivative biosynthetic process GO:1901137 183 0.075
phosphatidylinositol metabolic process GO:0046488 45 0.075
Mouse
positive regulation of secretion by cell GO:1903532 114 0.075
regulation of establishment of protein localization GO:0070201 181 0.074
positive regulation of acute inflammatory response GO:0002675 16 0.074
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.074
axon guidance GO:0007411 141 0.073
monoamine transport GO:0015844 33 0.073
positive regulation of response to wounding GO:1903036 66 0.073
interleukin 6 production GO:0032635 58 0.073
t helper 17 cell chemotaxis GO:0035705 1 0.072
digestive system development GO:0055123 200 0.072
eosinophil activation involved in immune response GO:0002278 1 0.072
regulation of cellular component size GO:0032535 121 0.072
regulation of t cell receptor signaling pathway GO:0050856 21 0.071
t cell extravasation GO:0072683 4 0.071
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.071
acute inflammatory response to antigenic stimulus GO:0002438 12 0.071
positive regulation of endocytosis GO:0045807 42 0.070
cellular amine metabolic process GO:0044106 44 0.069
purine nucleotide metabolic process GO:0006163 302 0.069
nucleotide catabolic process GO:0009166 217 0.069
ribonucleoside metabolic process GO:0009119 245 0.068
microglial cell activation GO:0001774 3 0.067
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.067
positive regulation of immunological synapse formation GO:2000522 1 0.067
negative regulation of exocytosis GO:0045920 12 0.067
action potential GO:0001508 78 0.066
innate immune response activating signal transduction GO:0002758 50 0.066
osteoclast differentiation GO:0030316 62 0.065
calcium ion transport into cytosol GO:0060402 48 0.065
cell type specific apoptotic process GO:0097285 268 0.064
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.064
positive regulation of cell development GO:0010720 237 0.064
nucleoside catabolic process GO:0009164 206 0.064
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.063
positive regulation of lymphocyte proliferation GO:0050671 70 0.063
multicellular organismal signaling GO:0035637 91 0.063
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.063
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.063
regulation of immunoglobulin mediated immune response GO:0002889 37 0.062
positive regulation of mapk cascade GO:0043410 170 0.062
regulation of hydrolase activity GO:0051336 246 0.062
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.062
antigen processing and presentation GO:0019882 47 0.062
positive regulation of cellular catabolic process GO:0031331 148 0.062
ribonucleotide metabolic process GO:0009259 291 0.062
neutrophil activation involved in immune response GO:0002283 8 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.062
epithelial tube morphogenesis GO:0060562 303 0.062
t cell differentiation GO:0030217 174 0.061
negative regulation of defense response GO:0031348 77 0.061
mast cell mediated immunity GO:0002448 20 0.060
multicellular organismal homeostasis GO:0048871 164 0.060
sensory perception GO:0007600 245 0.060
stem cell differentiation GO:0048863 268 0.060
plasma membrane organization GO:0007009 90 0.060
negative regulation of t cell activation GO:0050868 65 0.060
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.059
negative regulation of inflammatory response GO:0050728 61 0.059
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.059
actin cytoskeleton organization GO:0030036 220 0.059
ribonucleoside triphosphate metabolic process GO:0009199 220 0.059
regulation of cytokine biosynthetic process GO:0042035 59 0.059
regulation of endocytosis GO:0030100 69 0.059
regulation of ras protein signal transduction GO:0046578 114 0.059
regulation of rho gtpase activity GO:0032319 58 0.058
negative regulation of cytokine production GO:0001818 84 0.058
tissue homeostasis GO:0001894 115 0.058
ossification GO:0001503 216 0.058
regulation of t cell mediated immunity GO:0002709 34 0.058
myeloid leukocyte mediated immunity GO:0002444 42 0.057
angiogenesis GO:0001525 201 0.057
leukocyte chemotaxis GO:0030595 69 0.057
negative regulation of response to wounding GO:1903035 77 0.057
purine containing compound catabolic process GO:0072523 213 0.057
nucleoside triphosphate metabolic process GO:0009141 230 0.057
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.057
regulation of cell cycle GO:0051726 281 0.057
b cell proliferation GO:0042100 53 0.057
regulation of t cell differentiation GO:0045580 83 0.056
t cell differentiation in thymus GO:0033077 77 0.056
regulation of dendritic cell chemotaxis GO:2000508 1 0.056
regulation of neuron death GO:1901214 134 0.056
Mouse
regulation of coagulation GO:0050818 31 0.056
wound healing GO:0042060 157 0.056
Mouse
positive regulation of b cell mediated immunity GO:0002714 26 0.055
regulation of alpha beta t cell proliferation GO:0046640 18 0.055
positive regulation of gtpase activity GO:0043547 85 0.055
positive regulation of nucleotide metabolic process GO:0045981 114 0.055
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.055
regulation of gtp catabolic process GO:0033124 113 0.054
muscle contraction GO:0006936 101 0.054
cellular component assembly involved in morphogenesis GO:0010927 139 0.054
production of molecular mediator of immune response GO:0002440 103 0.054
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.054
intracellular protein transport GO:0006886 204 0.053
regulation of actin filament length GO:0030832 45 0.053
bone mineralization GO:0030282 54 0.053
cellular response to growth factor stimulus GO:0071363 197 0.052
positive regulation of hydrolase activity GO:0051345 148 0.052
positive regulation of transferase activity GO:0051347 167 0.052
Mouse
regulation of map kinase activity GO:0043405 120 0.052
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.052
cellular response to abiotic stimulus GO:0071214 56 0.052
negative regulation of t cell mediated immunity GO:0002710 9 0.052
regulation of erk1 and erk2 cascade GO:0070372 71 0.051
granulocyte activation GO:0036230 10 0.051
cell recognition GO:0008037 83 0.051
glycerolipid metabolic process GO:0046486 122 0.051
Mouse
positive regulation of leukocyte degranulation GO:0043302 10 0.051
response to radiation GO:0009314 165 0.051
positive regulation of adaptive immune response GO:0002821 61 0.051
nucleotide metabolic process GO:0009117 332 0.051
negative regulation of eosinophil degranulation GO:0043310 1 0.051
regulation of wound healing GO:0061041 40 0.050
cellular response to lipid GO:0071396 145 0.050
platelet degranulation GO:0002576 6 0.050
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.050
neuron migration GO:0001764 122 0.049
learning or memory GO:0007611 148 0.049
Worm
organonitrogen compound catabolic process GO:1901565 264 0.049
toll like receptor signaling pathway GO:0002224 38 0.049
positive regulation of interleukin 18 production GO:0032741 2 0.048
serotonin secretion GO:0001820 8 0.048
purine nucleoside metabolic process GO:0042278 241 0.048
regulation of nucleotide catabolic process GO:0030811 122 0.048
regulation of b cell mediated immunity GO:0002712 37 0.048
response to host GO:0075136 3 0.047
regulation of b cell activation GO:0050864 81 0.047
regulation of cytokine production involved in immune response GO:0002718 26 0.047
glycosyl compound catabolic process GO:1901658 206 0.047
cytosolic calcium ion transport GO:0060401 48 0.047
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.047
b cell activation GO:0042113 161 0.047
Mouse
cellular homeostasis GO:0019725 240 0.047
Mouse
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.047
regulation of cellular catabolic process GO:0031329 242 0.046
granulocyte chemotaxis GO:0071621 39 0.046
regulation of neuron differentiation GO:0045664 281 0.046
regulation of cytokine secretion GO:0050707 61 0.046
positive regulation of leukocyte proliferation GO:0070665 73 0.046
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.045
inorganic ion transmembrane transport GO:0098660 234 0.045
Mouse
b cell activation involved in immune response GO:0002312 50 0.045
regulation of acute inflammatory response GO:0002673 27 0.044
gland development GO:0048732 330 0.044
activation of innate immune response GO:0002218 56 0.044
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.044
positive regulation of nervous system development GO:0051962 221 0.044
t cell mediated immunity GO:0002456 50 0.043
detection of molecule of bacterial origin GO:0032490 2 0.043
blood circulation GO:0008015 195 0.043
purine nucleoside triphosphate catabolic process GO:0009146 203 0.043
positive regulation of b cell activation GO:0050871 49 0.043
mast cell activation involved in immune response GO:0002279 20 0.043
forebrain development GO:0030900 302 0.043
regulation of mast cell activation involved in immune response GO:0033006 17 0.043
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.043
protein localization to membrane GO:0072657 108 0.043
regulation of transmembrane transport GO:0034762 128 0.042
Mouse
gliogenesis GO:0042063 141 0.042
alpha beta t cell differentiation GO:0046632 69 0.042
acute inflammatory response GO:0002526 41 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.042
maintenance of location GO:0051235 89 0.042
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.042
germ cell development GO:0007281 185 0.042
mast cell degranulation GO:0043303 19 0.042
cell maturation GO:0048469 127 0.042
regulation of leukocyte apoptotic process GO:2000106 56 0.042
regulation of interleukin 1 production GO:0032652 26 0.042
organic hydroxy compound transport GO:0015850 93 0.042
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.041
regulation of system process GO:0044057 200 0.041
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.041
regulation of epithelial cell proliferation GO:0050678 141 0.041
negative regulation of cell proliferation GO:0008285 296 0.041
innate immune response GO:0045087 157 0.041
circulatory system process GO:0003013 197 0.040
thymic t cell selection GO:0045061 22 0.040
fc epsilon receptor signaling pathway GO:0038095 3 0.040
regulation of rho protein signal transduction GO:0035023 71 0.040
positive regulation of regulated secretory pathway GO:1903307 10 0.040
regulation of interleukin 18 production GO:0032661 3 0.040
cell division GO:0051301 120 0.040
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.039
positive regulation of ion transport GO:0043270 65 0.039
positive regulation of monocyte chemotaxis GO:0090026 2 0.039
positive regulation of cytokine biosynthetic process GO:0042108 40 0.039
positive regulation of protein phosphorylation GO:0001934 242 0.039
Mouse
production of molecular mediator involved in inflammatory response GO:0002532 21 0.039
purine containing compound metabolic process GO:0072521 311 0.039
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.039
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.039
positive regulation of innate immune response GO:0045089 80 0.039
regulation of blood coagulation GO:0030193 28 0.039
negative regulation of cellular amine metabolic process GO:0033239 1 0.039
developmental maturation GO:0021700 193 0.038
morphogenesis of embryonic epithelium GO:0016331 159 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.038
cellular response to organonitrogen compound GO:0071417 145 0.038
regulation of interferon gamma production GO:0032649 57 0.038
intestinal epithelial structure maintenance GO:0060729 4 0.038
nucleoside metabolic process GO:0009116 246 0.038
heart morphogenesis GO:0003007 178 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.037
myeloid leukocyte cytokine production GO:0061082 12 0.037
regulation of cell cycle process GO:0010564 160 0.037
immunoglobulin mediated immune response GO:0016064 69 0.037
positive regulation of secretion GO:0051047 130 0.037
regulation of purine nucleotide catabolic process GO:0033121 122 0.037
regulation of actin cytoskeleton organization GO:0032956 84 0.037
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.037
interleukin 1 production GO:0032612 31 0.037
regulation of actin nucleation GO:0051125 4 0.037
striated muscle contraction GO:0006941 45 0.037
small molecule biosynthetic process GO:0044283 132 0.037
nucleotide biosynthetic process GO:0009165 78 0.037
blood vessel morphogenesis GO:0048514 285 0.037
neutrophil migration GO:1990266 37 0.037
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.037
positive regulation of vasoconstriction GO:0045907 4 0.036
response to light stimulus GO:0009416 135 0.036
regulation of cytoplasmic transport GO:1903649 112 0.036
regulation of cell projection organization GO:0031344 206 0.036
negative thymic t cell selection GO:0045060 12 0.036
positive regulation of humoral immune response GO:0002922 11 0.036
regulation of protein secretion GO:0050708 82 0.036
gtp catabolic process GO:0006184 143 0.036
epithelial cell proliferation GO:0050673 174 0.036
reactive oxygen species biosynthetic process GO:1903409 8 0.036
male gamete generation GO:0048232 285 0.036
transmission of nerve impulse GO:0019226 76 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
positive regulation of cytoplasmic transport GO:1903651 40 0.035
pattern recognition receptor signaling pathway GO:0002221 47 0.035
regulation of hemostasis GO:1900046 28 0.035
negative regulation of cellular component organization GO:0051129 194 0.035
cytokine metabolic process GO:0042107 71 0.034
glial cell differentiation GO:0010001 131 0.034
negative regulation of secretion GO:0051048 61 0.034
dna metabolic process GO:0006259 303 0.034
Mouse
interferon beta biosynthetic process GO:0045350 4 0.034
hypersensitivity GO:0002524 10 0.034
interleukin 18 production GO:0032621 4 0.034
regulation of hormone levels GO:0010817 211 0.034
regulation of actin filament based process GO:0032970 99 0.034
biomineral tissue development GO:0031214 64 0.034
positive regulation of interleukin 10 production GO:0032733 12 0.034
salivary gland development GO:0007431 37 0.034
lymphocyte mediated immunity GO:0002449 139 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
positive regulation of exocytosis GO:0045921 20 0.033
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.033
Mouse
skeletal system development GO:0001501 356 0.033
neuron projection guidance GO:0097485 141 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
mature dendritic cell differentiation GO:0097029 3 0.033
myeloid cell homeostasis GO:0002262 114 0.033
actin filament organization GO:0007015 113 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
eosinophil mediated immunity GO:0002447 1 0.033
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.033
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.033
nitrogen compound transport GO:0071705 271 0.033
regulation of myeloid leukocyte differentiation GO:0002761 58 0.033
regulation of ossification GO:0030278 112 0.033
regulation of cell size GO:0008361 72 0.032
regulation of interleukin 10 production GO:0032653 21 0.032
mesodermal cell migration GO:0008078 4 0.032
positive regulation of mast cell degranulation GO:0043306 10 0.032
negative regulation of b cell activation GO:0050869 27 0.032
ameboidal type cell migration GO:0001667 128 0.032

Pik3cg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.065
disease of anatomical entity DOID:7 0 0.065
musculoskeletal system disease DOID:17 0 0.047
cancer DOID:162 0 0.041
disease of cellular proliferation DOID:14566 0 0.041
organ system cancer DOID:0050686 0 0.041
disease by infectious agent DOID:0050117 0 0.037