Mus musculus

220 known processes

Pik3r1

phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)

(Aliases: C530050K14,PI3K,p50alpha,p85alpha,AA414921,p55alpha)

Pik3r1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.995
regulation of cellular ketone metabolic process GO:0010565 66 0.992
olfactory learning GO:0008355 2 0.991
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.982
Human Mouse Rat Worm
lipid phosphorylation GO:0046834 25 0.981
Mouse Rat Fly
regulation of zinc ion transport GO:0071579 2 0.979
amine metabolic process GO:0009308 45 0.978
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.978
Mouse Rat Fly
cellular ketone metabolic process GO:0042180 84 0.978
cellular amine metabolic process GO:0044106 44 0.976
regulation of transferase activity GO:0051338 263 0.975
Mouse Rat Fly
jnk cascade GO:0007254 72 0.966
positive regulation of cell migration GO:0030335 109 0.957
positive regulation of cellular amine metabolic process GO:0033240 5 0.955
regulation of insulin receptor signaling pathway GO:0046626 21 0.954
phospholipid metabolic process GO:0006644 87 0.951
Mouse Rat Fly
regulation of peptidyl serine phosphorylation GO:0033135 39 0.949
phosphatidylinositol biosynthetic process GO:0006661 15 0.949
Mouse Rat
mapk cascade GO:0000165 281 0.948
regulation of mapk cascade GO:0043408 248 0.947
positive regulation of lipid kinase activity GO:0090218 11 0.939
cellular lipid metabolic process GO:0044255 323 0.937
Mouse Rat Fly
phosphatidylinositol mediated signaling GO:0048015 41 0.937
Human
learning or memory GO:0007611 148 0.937
carbohydrate metabolic process GO:0005975 230 0.926
Rat
cell type specific apoptotic process GO:0097285 268 0.925
Rat
regulation of cellular amine metabolic process GO:0033238 20 0.920
positive regulation of cell motility GO:2000147 116 0.918
positive regulation of mapk cascade GO:0043410 170 0.905
cellular amino acid metabolic process GO:0006520 103 0.905
response to peptide hormone GO:0043434 127 0.900
Human Mouse Rat Worm
glycerophospholipid metabolic process GO:0006650 71 0.898
Mouse Rat Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.896
negative regulation of neuron death GO:1901215 98 0.887
regionalization GO:0003002 337 0.886
positive regulation of jnk cascade GO:0046330 46 0.877
negative regulation of phosphorylation GO:0042326 166 0.875
b cell activation GO:0042113 161 0.874
regulation of zinc ion transmembrane transport GO:0071580 2 0.872
regulation of cell migration GO:0030334 219 0.872
cognition GO:0050890 149 0.870
regulation of mast cell activation GO:0033003 21 0.860
positive regulation of intracellular transport GO:0032388 70 0.858
glycerolipid metabolic process GO:0046486 122 0.855
Mouse Rat Fly
myeloid cell differentiation GO:0030099 233 0.853
regulation of kinase activity GO:0043549 249 0.849
Mouse Rat Fly
phosphatidylinositol phosphorylation GO:0046854 23 0.848
Mouse Rat Fly
associative learning GO:0008306 61 0.847
insulin receptor signaling pathway GO:0008286 49 0.845
Mouse Rat Worm
coagulation GO:0050817 78 0.831
wnt signaling pathway GO:0016055 188 0.821
phosphatidylinositol 3 phosphate biosynthetic process GO:0036092 6 0.818
Mouse Rat
negative regulation of zinc ion transmembrane transport GO:0071583 2 0.817
b cell proliferation GO:0042100 53 0.814
gland development GO:0048732 330 0.814
regulation of protein kinase activity GO:0045859 232 0.810
gastrulation GO:0007369 116 0.809
inositol lipid mediated signaling GO:0048017 41 0.807
Human
cellular response to insulin stimulus GO:0032869 78 0.805
Mouse Rat Worm
regulation of stress activated mapk cascade GO:0032872 69 0.805
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.803
peptidyl serine phosphorylation GO:0018105 74 0.801
positive regulation of kinase activity GO:0033674 155 0.796
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.794
positive regulation of stress activated mapk cascade GO:0032874 48 0.792
protein kinase b signaling GO:0043491 74 0.791
glycerolipid biosynthetic process GO:0045017 50 0.783
Mouse Rat
digestive tract morphogenesis GO:0048546 147 0.782
osteoclast differentiation GO:0030316 62 0.780
cellular response to peptide GO:1901653 92 0.779
Human Mouse Rat Worm
chemotaxis GO:0006935 247 0.776
positive regulation of transferase activity GO:0051347 167 0.776
lymphocyte homeostasis GO:0002260 64 0.775
regulation of actin filament based process GO:0032970 99 0.774
protein localization to nucleus GO:0034504 121 0.774
regulation of lipid metabolic process GO:0019216 118 0.769
Mouse Rat Fly
neuron apoptotic process GO:0051402 142 0.752
cytokine production GO:0001816 319 0.748
intrinsic apoptotic signaling pathway GO:0097193 132 0.747
response to peptide GO:1901652 136 0.741
Human Mouse Rat Worm
small gtpase mediated signal transduction GO:0007264 97 0.739
regulation of lipid kinase activity GO:0043550 14 0.739
Mouse Rat Fly
negative regulation of phosphorus metabolic process GO:0010563 184 0.730
immune effector process GO:0002252 321 0.728
generation of precursor metabolites and energy GO:0006091 103 0.722
regulation of ion transport GO:0043269 215 0.702
cell adhesion GO:0007155 329 0.700
cellular response to hormone stimulus GO:0032870 150 0.699
Human Mouse Rat Worm
peptidyl serine modification GO:0018209 83 0.695
phosphatidylinositol metabolic process GO:0046488 45 0.684
Mouse Rat Fly
germ cell development GO:0007281 185 0.684
intracellular protein transport GO:0006886 204 0.683
regulation of cell motility GO:2000145 236 0.682
endocytosis GO:0006897 168 0.682
positive regulation of lipid metabolic process GO:0045834 40 0.681
ion transmembrane transport GO:0034220 361 0.680
cell matrix adhesion GO:0007160 68 0.679
negative regulation of cell proliferation GO:0008285 296 0.677
Rat
stress activated protein kinase signaling cascade GO:0031098 81 0.675
cell substrate adhesion GO:0031589 130 0.670
cellular response to organonitrogen compound GO:0071417 145 0.668
Human Mouse Rat Worm
actin cytoskeleton organization GO:0030036 220 0.665
positive regulation of map kinase activity GO:0043406 84 0.664
cytokine mediated signaling pathway GO:0019221 115 0.655
stress activated mapk cascade GO:0051403 80 0.652
regulation of leukocyte differentiation GO:1902105 159 0.649
b cell apoptotic process GO:0001783 19 0.647
erythrocyte differentiation GO:0030218 88 0.622
cellular glucan metabolic process GO:0006073 32 0.621
regulation of mast cell degranulation GO:0043304 16 0.620
regulation of b cell activation GO:0050864 81 0.617
actin cytoskeleton reorganization GO:0031532 21 0.603
regulation of actin cytoskeleton organization GO:0032956 84 0.595
negative regulation of transferase activity GO:0051348 85 0.595
negative regulation of phosphate metabolic process GO:0045936 184 0.592
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.592
extrinsic apoptotic signaling pathway GO:0097191 126 0.589
forebrain development GO:0030900 302 0.585
regulation of b cell proliferation GO:0030888 39 0.580
b cell differentiation GO:0030183 78 0.579
polysaccharide metabolic process GO:0005976 39 0.572
mast cell degranulation GO:0043303 19 0.569
regulation of jnk cascade GO:0046328 62 0.567
myeloid leukocyte differentiation GO:0002573 119 0.565
regulation of dna methylation GO:0044030 12 0.555
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.542
negative regulation of kinase activity GO:0033673 81 0.542
cation homeostasis GO:0055080 212 0.541
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.534
cation transport GO:0006812 399 0.528
leukocyte proliferation GO:0070661 172 0.523
multicellular organism growth GO:0035264 161 0.516
positive regulation of secretion GO:0051047 130 0.515
glucan metabolic process GO:0044042 32 0.507
positive regulation of protein kinase activity GO:0045860 144 0.504
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.503
circulatory system process GO:0003013 197 0.496
Rat
calcium ion homeostasis GO:0055074 127 0.496
digestive tract development GO:0048565 190 0.494
lipid biosynthetic process GO:0008610 179 0.489
Mouse Rat
cellular carbohydrate metabolic process GO:0044262 119 0.489
positive regulation of secretion by cell GO:1903532 114 0.487
lymphocyte proliferation GO:0046651 164 0.486
spermatogenesis GO:0007283 284 0.485
peptidyl amino acid modification GO:0018193 336 0.485
metal ion homeostasis GO:0055065 189 0.482
positive regulation of insulin secretion GO:0032024 26 0.481
apoptotic signaling pathway GO:0097190 306 0.480
b cell receptor signaling pathway GO:0050853 20 0.475
regulation of secretion GO:0051046 274 0.475
negative regulation of fibroblast apoptotic process GO:2000270 6 0.474
lymphocyte apoptotic process GO:0070227 54 0.473
t cell differentiation GO:0030217 174 0.469
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.468
cellular polysaccharide metabolic process GO:0044264 38 0.468
regulation of leukocyte apoptotic process GO:2000106 56 0.467
regulation of neuron death GO:1901214 134 0.466
regulation of neuron apoptotic process GO:0043523 122 0.461
regulation of cytoplasmic transport GO:1903649 112 0.458
phospholipid biosynthetic process GO:0008654 36 0.456
Mouse Rat
regulation of vesicle mediated transport GO:0060627 139 0.456
positive regulation of jun kinase activity GO:0043507 30 0.452
lipid localization GO:0010876 126 0.450
macromolecule methylation GO:0043414 120 0.447
protein localization to organelle GO:0033365 185 0.446
leukocyte activation involved in immune response GO:0002366 126 0.443
regulation of cell substrate adhesion GO:0010810 73 0.440
lipid modification GO:0030258 65 0.440
Mouse Rat Fly
positive regulation of apoptotic process GO:0043065 217 0.440
negative regulation of neuron apoptotic process GO:0043524 92 0.437
ribonucleoside triphosphate metabolic process GO:0009199 220 0.433
monosaccharide metabolic process GO:0005996 106 0.431
Rat
leukocyte apoptotic process GO:0071887 71 0.430
cell maturation GO:0048469 127 0.429
genetic imprinting GO:0071514 27 0.429
positive regulation of cell adhesion GO:0045785 80 0.423
dna metabolic process GO:0006259 303 0.419
response to insulin GO:0032868 100 0.418
Mouse Rat Worm
positive regulation of peptide secretion GO:0002793 33 0.417
regulation of map kinase activity GO:0043405 120 0.417
protein autophosphorylation GO:0046777 61 0.416
cellular response to cytokine stimulus GO:0071345 189 0.416
homeostasis of number of cells GO:0048872 210 0.415
regulation of lymphocyte activation GO:0051249 240 0.414
response to oxidative stress GO:0006979 123 0.407
glucose transport GO:0015758 56 0.406
leukocyte differentiation GO:0002521 342 0.401
oogenesis GO:0048477 56 0.399
regulation of genetic imprinting GO:2000653 5 0.392
peptidyl tyrosine modification GO:0018212 145 0.386
regulation of myeloid cell differentiation GO:0045637 96 0.386
ribose phosphate metabolic process GO:0019693 291 0.381
male gamete generation GO:0048232 285 0.374
positive regulation of fatty acid beta oxidation GO:0032000 1 0.374
regulated secretory pathway GO:0045055 32 0.373
mast cell activation involved in immune response GO:0002279 20 0.373
epithelium migration GO:0090132 63 0.372
response to growth factor GO:0070848 198 0.371
Rat
positive regulation of chemotaxis GO:0050921 38 0.370
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.370
activation of immune response GO:0002253 138 0.369
regulation of chemotaxis GO:0050920 53 0.367
female gamete generation GO:0007292 74 0.366
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.363
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.361
inorganic ion transmembrane transport GO:0098660 234 0.361
energy derivation by oxidation of organic compounds GO:0015980 77 0.360
regulation of organelle organization GO:0033043 289 0.359
protein import into nucleus GO:0006606 95 0.358
cell chemotaxis GO:0060326 81 0.357
regulation of cell size GO:0008361 72 0.357
Fly
regulation of mast cell activation involved in immune response GO:0033006 17 0.355
monocarboxylic acid metabolic process GO:0032787 191 0.354
positive regulation of lipid catabolic process GO:0050996 6 0.352
negative regulation of molecular function GO:0044092 258 0.351
regulation of jun kinase activity GO:0043506 40 0.351
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.345
regulation of membrane potential GO:0042391 192 0.343
energy reserve metabolic process GO:0006112 39 0.342
myeloid cell homeostasis GO:0002262 114 0.341
cytoplasmic transport GO:0016482 234 0.341
activation of mapk activity GO:0000187 59 0.338
myeloid cell activation involved in immune response GO:0002275 34 0.338
gamma delta t cell differentiation GO:0042492 11 0.336
regulation of ion transmembrane transport GO:0034765 119 0.335
zinc ion transmembrane transport GO:0071577 10 0.329
g protein coupled receptor signaling pathway GO:0007186 243 0.328
epithelial cell migration GO:0010631 63 0.328
regulation of cell adhesion GO:0030155 154 0.327
cellular metal ion homeostasis GO:0006875 151 0.327
regulation of intracellular transport GO:0032386 159 0.326
positive regulation of apoptotic signaling pathway GO:2001235 95 0.326
positive regulation of b cell proliferation GO:0030890 24 0.325
oxidation reduction process GO:0055114 342 0.322
regulation of cell activation GO:0050865 289 0.321
epidermal growth factor receptor signaling pathway GO:0007173 28 0.318
positive regulation of gamma delta t cell differentiation GO:0045588 6 0.316
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.315
Human
posttranscriptional regulation of gene expression GO:0010608 155 0.314
positive regulation of cell activation GO:0050867 158 0.311
tor signaling GO:0031929 21 0.311
regulation of cellular component size GO:0032535 121 0.310
Fly
regulation of leukocyte mediated immunity GO:0002703 104 0.308
axon guidance GO:0007411 141 0.308
syncytium formation by plasma membrane fusion GO:0000768 42 0.307
phagocytosis GO:0006909 66 0.303
positive regulation of cellular component biogenesis GO:0044089 94 0.299
regulation of glucose transport GO:0010827 32 0.298
positive regulation of protein phosphorylation GO:0001934 242 0.297
Rat
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.293
cellular calcium ion homeostasis GO:0006874 119 0.293
positive regulation of regulated secretory pathway GO:1903307 10 0.293
organophosphate biosynthetic process GO:0090407 122 0.291
Mouse Rat
cellular divalent inorganic cation homeostasis GO:0072503 127 0.290
neuron projection guidance GO:0097485 141 0.288
cellular response to biotic stimulus GO:0071216 92 0.287
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.287
regulation of secretion by cell GO:1903530 249 0.286
learning GO:0007612 98 0.285
divalent inorganic cation homeostasis GO:0072507 138 0.282
hemostasis GO:0007599 78 0.280
cell migration involved in gastrulation GO:0042074 13 0.277
mast cell activation GO:0045576 27 0.277
mitotic cell cycle GO:0000278 195 0.277
regulation of neuronal synaptic plasticity GO:0048168 30 0.276
guanosine containing compound catabolic process GO:1901069 144 0.275
cellular response to starvation GO:0009267 57 0.274
regulation of b cell differentiation GO:0045577 23 0.273
cell activation involved in immune response GO:0002263 126 0.273
regulation of cellular component biogenesis GO:0044087 181 0.272
exocytosis GO:0006887 121 0.271
glycogen metabolic process GO:0005977 32 0.270
rhythmic process GO:0048511 174 0.267
positive regulation of cytoskeleton organization GO:0051495 49 0.263
negative regulation of map kinase activity GO:0043407 34 0.262
positive regulation of growth GO:0045927 104 0.262
positive regulation of leukocyte degranulation GO:0043302 10 0.262
inorganic cation transmembrane transport GO:0098662 207 0.262
b cell homeostasis GO:0001782 34 0.258
negative regulation of protein metabolic process GO:0051248 282 0.256
Rat
negative regulation of mapk cascade GO:0043409 65 0.255
translation GO:0006412 93 0.253
axonogenesis GO:0007409 274 0.251
maintenance of location GO:0051235 89 0.250
regulation of reactive oxygen species metabolic process GO:2000377 40 0.248
regulation of mast cell proliferation GO:0070666 4 0.247
negative regulation of erbb signaling pathway GO:1901185 7 0.246
long term memory GO:0007616 15 0.244
skin development GO:0043588 220 0.244
regulation of cell division GO:0051302 76 0.242
positive regulation of organelle organization GO:0010638 128 0.241
nucleocytoplasmic transport GO:0006913 139 0.240
regulation of lymphocyte differentiation GO:0045619 107 0.239
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.239
negative regulation of zinc ion transport GO:0071582 2 0.239
negative regulation of cellular amine metabolic process GO:0033239 1 0.238
germ line stem cell division GO:0042078 2 0.235
cellular chemical homeostasis GO:0055082 215 0.234
organelle localization GO:0051640 179 0.232
stem cell differentiation GO:0048863 268 0.230
purine nucleoside triphosphate catabolic process GO:0009146 203 0.229
regulation of erk1 and erk2 cascade GO:0070372 71 0.225
blood coagulation GO:0007596 76 0.224
apical constriction GO:0003383 4 0.224
ras protein signal transduction GO:0007265 77 0.224
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.223
regulation of ras protein signal transduction GO:0046578 114 0.223
regulation of epidermal growth factor receptor signaling pathway GO:0042058 13 0.222
positive regulation of mast cell degranulation GO:0043306 10 0.222
nitrogen compound transport GO:0071705 271 0.222
regulation of lymphocyte apoptotic process GO:0070228 41 0.220
neuron death GO:0070997 154 0.220
negative regulation of cellular protein metabolic process GO:0032269 247 0.218
Rat
hexose metabolic process GO:0019318 98 0.217
Rat
regulation of cellular response to stress GO:0080135 159 0.217
respiratory system development GO:0060541 190 0.216
antigen receptor mediated signaling pathway GO:0050851 64 0.216
myotube differentiation GO:0014902 105 0.216
Rat
protein oligomerization GO:0051259 67 0.215
respiratory tube development GO:0030323 167 0.215
cellular ion homeostasis GO:0006873 165 0.215
erbb signaling pathway GO:0038127 32 0.214
embryonic placenta development GO:0001892 98 0.214
regulation of synaptic plasticity GO:0048167 87 0.212
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.211
monosaccharide transport GO:0015749 58 0.210
organophosphate catabolic process GO:0046434 232 0.209
regulation of transmembrane transport GO:0034762 128 0.208
cellularization GO:0007349 1 0.208
neuron migration GO:0001764 122 0.207
negative regulation of myeloid cell differentiation GO:0045638 38 0.206
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.205
synaptic growth at neuromuscular junction GO:0051124 6 0.205
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.205
positive regulation of protein transport GO:0051222 93 0.205
regulation of homeostatic process GO:0032844 182 0.202
membrane organization GO:0061024 245 0.202
stem cell development GO:0048864 219 0.202
positive regulation of programmed cell death GO:0043068 218 0.201
positive regulation of cytokine production GO:0001819 174 0.200
circadian rhythm GO:0007623 114 0.200
regulation of cytokine production GO:0001817 266 0.199
synaptic transmission GO:0007268 329 0.198
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.198
positive regulation of peptide hormone secretion GO:0090277 31 0.195
mast cell proliferation GO:0070662 4 0.195
regulation of hormone levels GO:0010817 211 0.195
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.194
regulation of organ growth GO:0046620 61 0.194
hypomethylation of cpg island GO:0044029 1 0.191
regulation of erbb signaling pathway GO:1901184 16 0.190
nuclear division GO:0000280 158 0.189
morphogenesis of embryonic epithelium GO:0016331 159 0.188
cell division GO:0051301 120 0.188
reactive oxygen species metabolic process GO:0072593 84 0.186
platelet activation GO:0030168 40 0.186
cell fate commitment GO:0045165 210 0.185
positive regulation of behavior GO:0048520 40 0.185
immune response activating signal transduction GO:0002757 116 0.185
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.184
regulation of response to drug GO:2001023 2 0.184
regulation of intracellular protein transport GO:0033157 82 0.184
regulation of rho gtpase activity GO:0032319 58 0.184
purine ribonucleotide metabolic process GO:0009150 290 0.184
myeloid leukocyte activation GO:0002274 83 0.183
regulation of b cell apoptotic process GO:0002902 13 0.181
regulation of hormone secretion GO:0046883 88 0.180
hexose transport GO:0008645 56 0.179
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.179
protein targeting GO:0006605 143 0.178
calcium ion transport GO:0006816 159 0.178
regulation of fatty acid beta oxidation GO:0031998 1 0.177
regulation of nucleocytoplasmic transport GO:0046822 73 0.176
toll like receptor signaling pathway GO:0002224 38 0.175
protein import GO:0017038 101 0.174
sensory perception of mechanical stimulus GO:0050954 107 0.174
regulation of cellular response to insulin stimulus GO:1900076 30 0.173
carbohydrate transport GO:0008643 62 0.171
peptide secretion GO:0002790 114 0.171
glycosyl compound catabolic process GO:1901658 206 0.171
adherens junction organization GO:0034332 28 0.170
purine ribonucleoside metabolic process GO:0046128 241 0.170
ameboidal type cell migration GO:0001667 128 0.170
actin filament based movement GO:0030048 23 0.170
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.170
response to organonitrogen compound GO:0010243 246 0.169
Human Mouse Rat Worm
cellular homeostasis GO:0019725 240 0.168
organelle fission GO:0048285 170 0.167
male sex differentiation GO:0046661 109 0.167
epithelial cell proliferation GO:0050673 174 0.165
release of sequestered calcium ion into cytosol GO:0051209 42 0.165
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.165
negative regulation of protein modification process GO:0031400 163 0.164
positive regulation of nervous system development GO:0051962 221 0.163
granulocyte chemotaxis GO:0071621 39 0.162
positive regulation of lymphocyte activation GO:0051251 140 0.162
regulation of wnt signaling pathway GO:0030111 123 0.161
regulation of glucose metabolic process GO:0010906 60 0.161
positive regulation of transcription by galactose GO:0000411 1 0.160
leukocyte mediated immunity GO:0002443 174 0.160
cell growth GO:0016049 130 0.158
lipid catabolic process GO:0016042 69 0.157
regulation of b cell receptor signaling pathway GO:0050855 9 0.157
male germ line stem cell asymmetric division GO:0048133 2 0.156
positive regulation of gamma delta t cell activation GO:0046645 6 0.156
leukocyte migration GO:0050900 124 0.155
regulation of regulated secretory pathway GO:1903305 20 0.154
regulation of establishment of protein localization GO:0070201 181 0.153
adaptive immune response GO:0002250 155 0.153
regulation of body fluid levels GO:0050878 162 0.153
regulation of lipid catabolic process GO:0050994 15 0.153
positive regulation of leukocyte differentiation GO:1902107 86 0.152
detection of external stimulus GO:0009581 61 0.152
nucleotide metabolic process GO:0009117 332 0.151
regulation of cell cycle GO:0051726 281 0.151
dna hypomethylation GO:0044028 1 0.150
nucleoside phosphate metabolic process GO:0006753 338 0.150
defecation GO:0030421 1 0.149
development of primary sexual characteristics GO:0045137 143 0.149
peptidyl tyrosine phosphorylation GO:0018108 143 0.149
positive regulation of immune effector process GO:0002699 107 0.149
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 6 0.148
regulation of peptide transport GO:0090087 91 0.148
erk1 and erk2 cascade GO:0070371 77 0.148
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.148
insulin like growth factor receptor signaling pathway GO:0048009 21 0.147
Human Rat
methylation GO:0032259 134 0.147
dendrite development GO:0016358 115 0.147
regulation of homotypic cell cell adhesion GO:0034110 13 0.146
lateral inhibition GO:0046331 1 0.146
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.145
innate immune response GO:0045087 157 0.145
regulation of protein binding GO:0043393 60 0.145
digestive system development GO:0055123 200 0.145
positive regulation of epithelial cell migration GO:0010634 19 0.144
negative regulation of immune system process GO:0002683 209 0.144
positive regulation of podosome assembly GO:0071803 3 0.144
formation of primary germ layer GO:0001704 77 0.144
regulation of carbohydrate metabolic process GO:0006109 75 0.143
positive regulation of b cell activation GO:0050871 49 0.143
dna methylation GO:0006306 43 0.143
response to organic cyclic compound GO:0014070 198 0.143
Rat
asymmetric stem cell division GO:0098722 3 0.143
regulation of protein stability GO:0031647 52 0.142
regulation of erythrocyte differentiation GO:0045646 23 0.139
regulation of binding GO:0051098 111 0.139
negative regulation of synapse assembly GO:0051964 3 0.139
regulation of mitotic cell cycle GO:0007346 126 0.138
body morphogenesis GO:0010171 45 0.138
positive regulation of dendritic cell apoptotic process GO:2000670 3 0.137
positive regulation of intracellular protein transport GO:0090316 42 0.137
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.137
regulation of gamma delta t cell activation GO:0046643 9 0.137
cellular response to lipopolysaccharide GO:0071222 77 0.136
regulation of cytoskeleton organization GO:0051493 122 0.136
regulation of lymphocyte proliferation GO:0050670 117 0.136
rac protein signal transduction GO:0016601 13 0.136
leukocyte chemotaxis GO:0030595 69 0.134
purine ribonucleotide catabolic process GO:0009154 208 0.133
endothelial cell migration GO:0043542 44 0.133
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.132
somitogenesis GO:0001756 69 0.132
fatty acid metabolic process GO:0006631 121 0.132
regulation of cell projection organization GO:0031344 206 0.132
carbohydrate derivative biosynthetic process GO:1901137 183 0.131
female sex differentiation GO:0046660 84 0.131
regulation of cytokine secretion GO:0050707 61 0.130
positive regulation of leukocyte proliferation GO:0070665 73 0.129
developmental maturation GO:0021700 193 0.128
organ growth GO:0035265 117 0.128
multicellular organismal aging GO:0010259 24 0.128
Worm
regulation of dendritic cell apoptotic process GO:2000668 3 0.127
peptidyl threonine phosphorylation GO:0018107 31 0.127
leukocyte degranulation GO:0043299 27 0.126
glycerophospholipid biosynthetic process GO:0046474 32 0.126
Mouse Rat
regulation of hydrolase activity GO:0051336 246 0.126
negative regulation of cell motility GO:2000146 61 0.125
regulation of podosome assembly GO:0071801 3 0.125
ribonucleoside catabolic process GO:0042454 206 0.125
dna modification GO:0006304 50 0.125
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.124
organonitrogen compound catabolic process GO:1901565 264 0.124

Pik3r1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.797
disease of cellular proliferation DOID:14566 0 0.797
organ system cancer DOID:0050686 0 0.709
gastrointestinal system cancer DOID:3119 0 0.246
intestinal cancer DOID:10155 0 0.164
large intestine cancer DOID:5672 0 0.137
colon cancer DOID:219 0 0.137
colorectal cancer DOID:9256 0 0.137
diabetes mellitus DOID:9351 0 0.129
disease of metabolism DOID:0014667 0 0.129
carbohydrate metabolism disease DOID:0050013 0 0.129
glucose metabolism disease DOID:4194 0 0.129
acquired metabolic disease DOID:0060158 0 0.129