Mus musculus

40 known processes

Pinx1

PIN2/TERF1 interacting, telomerase inhibitor 1

(Aliases: 2610028A01Rik,2210403I16Rik,LPTS,AU024023,67-11-3,MGC144540,LPTS1)

Pinx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.133
nuclear division GO:0000280 158 0.132
dna endoreduplication GO:0042023 4 0.114
negative regulation of cell cycle GO:0045786 123 0.103
regulation of mitotic cell cycle GO:0007346 126 0.098
positive regulation of apoptotic process GO:0043065 217 0.093
regulation of cell cycle GO:0051726 281 0.089
amine metabolic process GO:0009308 45 0.087
mitotic cell cycle GO:0000278 195 0.074
organelle fission GO:0048285 170 0.073
positive regulation of cell death GO:0010942 224 0.072
cellular amino acid metabolic process GO:0006520 103 0.072
positive regulation of programmed cell death GO:0043068 218 0.069
regulation of cell cycle process GO:0010564 160 0.065
regulation of organelle organization GO:0033043 289 0.064
negative regulation of mitotic cell cycle GO:0045930 58 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.060
regulation of cellular catabolic process GO:0031329 242 0.059
striated muscle tissue development GO:0014706 293 0.058
mitotic cell cycle process GO:1903047 159 0.057
regulation of cellular amino acid metabolic process GO:0006521 5 0.054
muscle tissue development GO:0060537 308 0.053
germ cell development GO:0007281 185 0.052
macromolecule catabolic process GO:0009057 281 0.052
cellular ketone metabolic process GO:0042180 84 0.049
dna replication GO:0006260 52 0.048
microtubule cytoskeleton organization GO:0000226 157 0.048
cellular amine metabolic process GO:0044106 44 0.048
regulation of exit from mitosis GO:0007096 1 0.047
meiotic cell cycle GO:0051321 122 0.047
microtubule based process GO:0007017 236 0.045
chromatin organization GO:0006325 206 0.044
muscle cell differentiation GO:0042692 261 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
negative regulation of dna replication GO:0008156 4 0.040
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 66 0.040
oxidation reduction process GO:0055114 342 0.040
leukocyte differentiation GO:0002521 342 0.039
regulation of kinase activity GO:0043549 249 0.039
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
hematopoietic progenitor cell differentiation GO:0002244 143 0.039
regulation of protein localization GO:0032880 231 0.038
apoptotic signaling pathway GO:0097190 306 0.037
cellular response to gamma radiation GO:0071480 4 0.036
reactive oxygen species metabolic process GO:0072593 84 0.035
regulation of transferase activity GO:0051338 263 0.035
Zebrafish
negative regulation of molecular function GO:0044092 258 0.034
Zebrafish
protein processing GO:0016485 163 0.034
rna processing GO:0006396 105 0.034
cell division GO:0051301 120 0.033
camera type eye development GO:0043010 266 0.031
response to radiation GO:0009314 165 0.031
regulation of proteolysis GO:0030162 164 0.031
negative regulation of protein metabolic process GO:0051248 282 0.030
negative regulation of protein modification process GO:0031400 163 0.030
protein maturation GO:0051604 176 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
cation transport GO:0006812 399 0.029
chromatin modification GO:0016568 187 0.029
regulation of cell cycle phase transition GO:1901987 77 0.028
response to organonitrogen compound GO:0010243 246 0.028
cellular homeostasis GO:0019725 240 0.027
mitotic nuclear division GO:0007067 48 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
g1 s transition of mitotic cell cycle GO:0000082 57 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
meiotic nuclear division GO:0007126 115 0.025
gene silencing GO:0016458 38 0.025
signal transduction by p53 class mediator GO:0072331 51 0.024
cation homeostasis GO:0055080 212 0.024
regulation of cellular response to stress GO:0080135 159 0.024
skeletal muscle organ development GO:0060538 163 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
mitotic cell cycle checkpoint GO:0007093 31 0.024
regulation of neuron differentiation GO:0045664 281 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
maintenance of location GO:0051235 89 0.024
organelle assembly GO:0070925 177 0.024
regulation of chromosome organization GO:0033044 83 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
regulation of hydrolase activity GO:0051336 246 0.023
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.023
skeletal system development GO:0001501 356 0.023
retina development in camera type eye GO:0060041 119 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
cellular response to acid chemical GO:0071229 68 0.023
male gamete generation GO:0048232 285 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
cell type specific apoptotic process GO:0097285 268 0.022
telencephalon development GO:0021537 186 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
response to drug GO:0042493 75 0.022
generation of precursor metabolites and energy GO:0006091 103 0.021
cytoplasmic transport GO:0016482 234 0.021
regulation of protein maturation GO:1903317 96 0.021
cytokine production GO:0001816 319 0.021
response to light stimulus GO:0009416 135 0.021
cell maturation GO:0048469 127 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
b cell activation GO:0042113 161 0.021
female gamete generation GO:0007292 74 0.021
regulation of membrane potential GO:0042391 192 0.021
regulation of cell activation GO:0050865 289 0.020
peptidyl amino acid modification GO:0018193 336 0.020
heterocycle catabolic process GO:0046700 280 0.020
chromosome segregation GO:0007059 48 0.020
cell cycle checkpoint GO:0000075 47 0.020
response to acid chemical GO:0001101 111 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
regulation of nuclear division GO:0051783 56 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
positive regulation of growth GO:0045927 104 0.019
gland development GO:0048732 330 0.019
cell growth GO:0016049 130 0.019
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.019
respiratory system development GO:0060541 190 0.019
regulation of binding GO:0051098 111 0.019
neuron death GO:0070997 154 0.019
cellular chemical homeostasis GO:0055082 215 0.019
regulation of cell division GO:0051302 76 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
spermatogenesis GO:0007283 284 0.019
transmembrane transport GO:0055085 412 0.019
striated muscle cell development GO:0055002 125 0.019
glycosyl compound metabolic process GO:1901657 246 0.018
mitotic cell cycle arrest GO:0071850 4 0.018
response to oxygen levels GO:0070482 62 0.018
regulation of protein kinase activity GO:0045859 232 0.018
stem cell differentiation GO:0048863 268 0.018
regulation of multi organism process GO:0043900 111 0.018
homeostasis of number of cells GO:0048872 210 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
cell adhesion GO:0007155 329 0.018
negative regulation of growth GO:0045926 99 0.018
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
histone modification GO:0016570 159 0.017
methylation GO:0032259 134 0.017
myeloid cell differentiation GO:0030099 233 0.017
regulation of anatomical structure size GO:0090066 178 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
forebrain development GO:0030900 302 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
regulation of mitotic cell cycle phase transition GO:1901990 73 0.017
regulation of cell growth GO:0001558 91 0.017
positive regulation of cell cycle GO:0045787 92 0.017
macromolecule methylation GO:0043414 120 0.017
response to organic cyclic compound GO:0014070 198 0.017
nuclear transport GO:0051169 139 0.017
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.017
regulation of secretion by cell GO:1903530 249 0.017
cell cycle g1 s phase transition GO:0044843 57 0.017
cell cycle switching GO:0060184 1 0.017
muscle cell development GO:0055001 133 0.017
ncrna processing GO:0034470 26 0.016
anatomical structure homeostasis GO:0060249 145 0.016
lymphocyte differentiation GO:0030098 242 0.016
cellular ion homeostasis GO:0006873 165 0.016
maturation of lsu rrna GO:0000470 1 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of cytokine production GO:0001817 266 0.016
cell aging GO:0007569 35 0.016
positive regulation of organelle organization GO:0010638 128 0.016
rhythmic process GO:0048511 174 0.016
dna integrity checkpoint GO:0031570 28 0.016
regulation of secretion GO:0051046 274 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
multi multicellular organism process GO:0044706 109 0.016
regulation of protein processing GO:0070613 96 0.016
cellular response to lipid GO:0071396 145 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
nitrogen compound transport GO:0071705 271 0.016
erythrocyte differentiation GO:0030218 88 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
response to peptide GO:1901652 136 0.015
regulation of defense response GO:0031347 233 0.015
negative regulation of immune system process GO:0002683 209 0.015
inflammatory response GO:0006954 244 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
regulation of myeloid leukocyte differentiation GO:0002761 58 0.015
ossification GO:0001503 216 0.015
t cell differentiation in thymus GO:0033077 77 0.015
chromosome organization involved in meiosis GO:0070192 39 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
regulation of protein catabolic process GO:0042176 108 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
regulation of cellular component size GO:0032535 121 0.015
cellular lipid metabolic process GO:0044255 323 0.015
cleavage involved in rrna processing GO:0000469 1 0.015
sequestering of metal ion GO:0051238 19 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
protein localization to organelle GO:0033365 185 0.015
multicellular organismal signaling GO:0035637 91 0.015
positive regulation of kinase activity GO:0033674 155 0.015
negative regulation of protein processing GO:0010955 79 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
negative regulation of proteolysis GO:0045861 74 0.015
oogenesis GO:0048477 56 0.015
sequestering of calcium ion GO:0051208 18 0.015
immune effector process GO:0002252 321 0.015
fertilization GO:0009566 127 0.015
epithelial cell development GO:0002064 159 0.015
spindle assembly involved in mitosis GO:0090307 4 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
actin cytoskeleton organization GO:0030036 220 0.014
mrna processing GO:0006397 63 0.014
response to decreased oxygen levels GO:0036293 59 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
response to inorganic substance GO:0010035 96 0.014
divalent metal ion transport GO:0070838 172 0.014
ion transmembrane transport GO:0034220 361 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
action potential GO:0001508 78 0.014
response to x ray GO:0010165 11 0.014
intracellular protein transport GO:0006886 204 0.014
intra s dna damage checkpoint GO:0031573 4 0.014
blood vessel morphogenesis GO:0048514 285 0.014
dna packaging GO:0006323 30 0.014
positive regulation of keratinocyte proliferation GO:0010838 4 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
myosin filament assembly GO:0031034 2 0.014
dna damage checkpoint GO:0000077 26 0.014
regulation of cell migration GO:0030334 219 0.014
signal transduction involved in dna damage checkpoint GO:0072422 3 0.014
response to oxidative stress GO:0006979 123 0.014
epithelial cell proliferation GO:0050673 174 0.014
sensory perception GO:0007600 245 0.014
positive regulation of cellular respiration GO:1901857 3 0.014
regulation of mapk cascade GO:0043408 248 0.014
blastocyst development GO:0001824 80 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.013
protein dna complex subunit organization GO:0071824 28 0.013
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.013
reciprocal dna recombination GO:0035825 16 0.013
divalent inorganic cation transport GO:0072511 178 0.013
response to hypoxia GO:0001666 58 0.013
regulation of peptidase activity GO:0052547 96 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
negative regulation of cell cycle process GO:0010948 69 0.013
locomotory behavior GO:0007626 195 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
telomere capping GO:0016233 4 0.013
mitochondrion organization GO:0007005 134 0.013
angiogenesis GO:0001525 201 0.013
regulation of homeostatic process GO:0032844 182 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.013
regulation of protein transport GO:0051223 163 0.013
myeloid cell homeostasis GO:0002262 114 0.013
cellular response to external stimulus GO:0071496 88 0.013
dna dependent dna replication GO:0006261 24 0.013
positive regulation of proteolysis GO:0045862 85 0.013
regulation of t cell activation GO:0050863 170 0.013
transmission of nerve impulse GO:0019226 76 0.013
leukocyte apoptotic process GO:0071887 71 0.013
regulation of dna replication GO:0006275 17 0.013
Zebrafish
lymphocyte proliferation GO:0046651 164 0.013
aromatic compound catabolic process GO:0019439 286 0.013
negative regulation of cell cycle phase transition GO:1901988 48 0.013
sensory organ morphogenesis GO:0090596 242 0.013
protein catabolic process GO:0030163 221 0.013
developmental maturation GO:0021700 193 0.013
protein import into nucleus GO:0006606 95 0.013
organelle localization GO:0051640 179 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.013
ribosome biogenesis GO:0042254 20 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
regulation of ion transport GO:0043269 215 0.013
intestinal epithelial structure maintenance GO:0060729 4 0.013
leukocyte proliferation GO:0070661 172 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
progesterone metabolic process GO:0042448 4 0.012
regulation of system process GO:0044057 200 0.012
purine containing compound metabolic process GO:0072521 311 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
positive regulation of striated muscle cell apoptotic process GO:0010663 3 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
negative regulation of protein maturation GO:1903318 79 0.012
covalent chromatin modification GO:0016569 163 0.012
cardiocyte differentiation GO:0035051 87 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
regulation of mitosis GO:0007088 29 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
regulation of muscle tissue development GO:1901861 97 0.012
notch signaling pathway GO:0007219 71 0.012
mrna metabolic process GO:0016071 84 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
respiratory tube development GO:0030323 167 0.012
negative regulation of chromosome organization GO:2001251 30 0.012
regulation of neuron death GO:1901214 134 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
regulation of ossification GO:0030278 112 0.012
cell cycle arrest GO:0007050 37 0.012
t cell differentiation GO:0030217 174 0.012
t cell proliferation GO:0042098 120 0.012
membrane organization GO:0061024 245 0.012
pallium development GO:0021543 120 0.012
tissue homeostasis GO:0001894 115 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
dephosphorylation GO:0016311 129 0.012
positive regulation of protein modification process GO:0031401 299 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
lipid biosynthetic process GO:0008610 179 0.011
adaptive immune response GO:0002250 155 0.011
chemotaxis GO:0006935 247 0.011
cellular response to oxidative stress GO:0034599 76 0.011
gliogenesis GO:0042063 141 0.011
positive regulation of cardiac muscle cell apoptotic process GO:0010666 3 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
maturation of 5 8s rrna GO:0000460 1 0.011
rna splicing GO:0008380 54 0.011
viral gene expression GO:0019080 3 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
limb development GO:0060173 166 0.011
nucleoside metabolic process GO:0009116 246 0.011
embryonic limb morphogenesis GO:0030326 126 0.011
regionalization GO:0003002 337 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
nucleotide metabolic process GO:0009117 332 0.011
negative regulation of protein catabolic process GO:0042177 36 0.011
stem cell maintenance GO:0019827 130 0.011
negative regulation of nervous system development GO:0051961 156 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
positive regulation of cytokine production GO:0001819 174 0.011
skeletal system morphogenesis GO:0048705 203 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
neuron apoptotic process GO:0051402 142 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
negative regulation of transferase activity GO:0051348 85 0.011
Zebrafish
regulation of cell motility GO:2000145 236 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
urogenital system development GO:0001655 261 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
meiotic cell cycle process GO:1903046 77 0.011
dna conformation change GO:0071103 37 0.011
negative regulation of cell development GO:0010721 169 0.010
carbohydrate homeostasis GO:0033500 128 0.010
ras protein signal transduction GO:0007265 77 0.010
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.010
dna repair GO:0006281 107 0.010
branching morphogenesis of an epithelial tube GO:0048754 159 0.010
negative regulation of kinase activity GO:0033673 81 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
positive regulation of cell development GO:0010720 237 0.010
maturation of ssu rrna GO:0030490 1 0.010
metaphase plate congression GO:0051310 2 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
b cell activation involved in immune response GO:0002312 50 0.010
attachment of spindle microtubules to kinetochore GO:0008608 4 0.010
regulation of cell size GO:0008361 72 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010

Pinx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.061
disease of cellular proliferation DOID:14566 0 0.061
organ system cancer DOID:0050686 0 0.045
gastrointestinal system cancer DOID:3119 0 0.017
sensory system disease DOID:0050155 0 0.014
disease of anatomical entity DOID:7 0 0.014
eye and adnexa disease DOID:1492 0 0.014
nervous system disease DOID:863 0 0.014
eye disease DOID:5614 0 0.014
immune system cancer DOID:0060083 0 0.014
hematologic cancer DOID:2531 0 0.014
large intestine cancer DOID:5672 0 0.012
intestinal cancer DOID:10155 0 0.012
disease of metabolism DOID:0014667 0 0.012
colon cancer DOID:219 0 0.010
colorectal cancer DOID:9256 0 0.010