Mus musculus

223 known processes

Pkd2

polycystic kidney disease 2

(Aliases: PC2,TRPP2,C030034P18Rik)

Pkd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.984
Mouse
detection of nodal flow GO:0003127 2 0.901
negative regulation of ryanodine sensitive calcium release channel activity GO:0060315 1 0.827
cell adhesion GO:0007155 329 0.771
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.705
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.698
response to growth factor GO:0070848 198 0.676
regulation of cell projection organization GO:0031344 206 0.653
skeletal system morphogenesis GO:0048705 203 0.651
Mouse
epithelial tube morphogenesis GO:0060562 303 0.607
regulation of cell adhesion GO:0030155 154 0.603
Mouse
single organismal cell cell adhesion GO:0016337 131 0.575
Mouse
regulation of membrane potential GO:0042391 192 0.573
canonical wnt signaling pathway GO:0060070 130 0.557
kidney development GO:0001822 213 0.533
cellular response to acidic ph GO:0071468 4 0.533
Mouse
digestive tract morphogenesis GO:0048546 147 0.502
skeletal system development GO:0001501 356 0.502
Mouse
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.474
cellular response to growth factor stimulus GO:0071363 197 0.466
determination of heart left right asymmetry GO:0061371 48 0.450
Human Zebrafish
regulation of organ morphogenesis GO:2000027 144 0.435
regulation of canonical wnt signaling pathway GO:0060828 82 0.426
regulation of protein localization GO:0032880 231 0.423
Human Mouse
regulation of neuron differentiation GO:0045664 281 0.390
negative regulation of cation channel activity GO:2001258 1 0.387
left right pattern formation GO:0060972 23 0.351
Mouse
epithelial cell migration GO:0010631 63 0.347
cellular metal ion homeostasis GO:0006875 151 0.335
digestive system development GO:0055123 200 0.333
regionalization GO:0003002 337 0.327
Zebrafish Mouse
regulation of chemotaxis GO:0050920 53 0.320
positive regulation of kinase activity GO:0033674 155 0.319
Human
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.316
positive regulation of protein kinase activity GO:0045860 144 0.307
Human
hindbrain development GO:0030902 128 0.305
cell substrate adhesion GO:0031589 130 0.303
sensory perception of sour taste GO:0050915 2 0.303
Mouse
determination of left right symmetry GO:0007368 80 0.302
stem cell development GO:0048864 219 0.301
mitotic cell cycle process GO:1903047 159 0.285
Human Mouse
sequestering of metal ion GO:0051238 19 0.279
response to lipopolysaccharide GO:0032496 128 0.279
heart morphogenesis GO:0003007 178 0.259
Human Zebrafish
spinal cord development GO:0021510 81 0.245
Human
epithelium migration GO:0090132 63 0.240
embryonic heart tube left right pattern formation GO:0060971 5 0.233
connective tissue development GO:0061448 179 0.223
Mouse
positive regulation of transferase activity GO:0051347 167 0.219
Human
regulation of nucleotide metabolic process GO:0006140 169 0.219
cilium morphogenesis GO:0060271 102 0.217
regulation of cell substrate adhesion GO:0010810 73 0.217
nephron development GO:0072006 109 0.217
Human Zebrafish
ensheathment of neurons GO:0007272 76 0.208
limb morphogenesis GO:0035108 149 0.206
defense response to other organism GO:0098542 197 0.205
regulation of protein stability GO:0031647 52 0.202
myeloid leukocyte differentiation GO:0002573 119 0.200
positive regulation of cell motility GO:2000147 116 0.200
regulation of mitotic spindle organization GO:0060236 2 0.199
Mouse
gland development GO:0048732 330 0.197
regulation of purine nucleotide metabolic process GO:1900542 169 0.196
positive regulation of protein kinase b signaling GO:0051897 32 0.195
response to transforming growth factor beta GO:0071559 88 0.189
hematopoietic progenitor cell differentiation GO:0002244 143 0.188
ameboidal type cell migration GO:0001667 128 0.187
neural tube development GO:0021915 160 0.182
Human
regulation of transferase activity GO:0051338 263 0.181
Human
positive regulation of protein phosphorylation GO:0001934 242 0.178
Human
homeostasis of number of cells GO:0048872 210 0.177
embryonic limb morphogenesis GO:0030326 126 0.177
regulation of cell motility GO:2000145 236 0.172
germ cell development GO:0007281 185 0.172
protein localization to nucleus GO:0034504 121 0.169
Human Mouse
cilium assembly GO:0042384 81 0.168
fertilization GO:0009566 127 0.166
Mouse
sequestering of calcium ion GO:0051208 18 0.165
regulation of cellular response to growth factor stimulus GO:0090287 82 0.165
gastrulation GO:0007369 116 0.164
retina development in camera type eye GO:0060041 119 0.163
regulation of protein targeting GO:1903533 61 0.163
Human Mouse
negative regulation of ossification GO:0030279 49 0.161
calcium ion transport into cytosol GO:0060402 48 0.160
multi multicellular organism process GO:0044706 109 0.158
Worm
positive regulation of chemotaxis GO:0050921 38 0.155
positive regulation of cell migration GO:0030335 109 0.154
regulation of cell migration GO:0030334 219 0.151
ascending thin limb development GO:0072021 2 0.146
Human
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.145
metanephric ascending thin limb development GO:0072218 2 0.144
Human
cerebellum development GO:0021549 77 0.142
cell migration involved in gastrulation GO:0042074 13 0.141
microtubule based process GO:0007017 236 0.139
Mouse
positive regulation of cell projection organization GO:0031346 95 0.138
regulation of leukocyte differentiation GO:1902105 159 0.138
mitotic cell cycle GO:0000278 195 0.136
Human Mouse
positive regulation of hydrolase activity GO:0051345 148 0.135
respiratory tube development GO:0030323 167 0.134
regulation of protein transport GO:0051223 163 0.129
Human Mouse
regulation of proteolysis GO:0030162 164 0.129
Mouse
multicellular organismal reproductive behavior GO:0033057 23 0.128
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.128
regulation of ion transport GO:0043269 215 0.127
regulation of wnt signaling pathway GO:0030111 123 0.127
positive regulation of apoptotic process GO:0043065 217 0.126
small gtpase mediated signal transduction GO:0007264 97 0.123
regulation of intracellular transport GO:0032386 159 0.122
Human Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.121
Human Zebrafish
bone morphogenesis GO:0060349 78 0.120
regulation of establishment of protein localization GO:0070201 181 0.119
Human Mouse
negative regulation of homeostatic process GO:0032845 71 0.119
cellular ketone metabolic process GO:0042180 84 0.119
axonal fasciculation GO:0007413 15 0.116
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.116
regulation of cell cycle GO:0051726 281 0.113
positive regulation of axon extension GO:0045773 20 0.111
metencephalon development GO:0022037 89 0.110
neuron projection guidance GO:0097485 141 0.108
mapk cascade GO:0000165 281 0.108
organic hydroxy compound transport GO:0015850 93 0.107
regulation of homeostatic process GO:0032844 182 0.106
leukocyte differentiation GO:0002521 342 0.106
amine metabolic process GO:0009308 45 0.106
hindbrain morphogenesis GO:0021575 46 0.104
nephron tubule morphogenesis GO:0072078 68 0.103
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.103
organelle assembly GO:0070925 177 0.103
action potential GO:0001508 78 0.102
pigmentation GO:0043473 71 0.100
negative regulation of cell migration GO:0030336 59 0.099
negative regulation of immune system process GO:0002683 209 0.099
regulation of lymphocyte differentiation GO:0045619 107 0.098
protein kinase b signaling GO:0043491 74 0.097
regulation of cellular component size GO:0032535 121 0.094
regulation of proteasomal protein catabolic process GO:0061136 46 0.093
Mouse
liver development GO:0001889 66 0.093
urogenital system development GO:0001655 261 0.092
positive regulation of cell death GO:0010942 224 0.091
cellular potassium ion transport GO:0071804 43 0.089
organophosphate catabolic process GO:0046434 232 0.088
macromolecule catabolic process GO:0009057 281 0.088
Mouse
regulation of t cell differentiation GO:0045580 83 0.087
protein catabolic process GO:0030163 221 0.086
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.086
positive regulation of nervous system development GO:0051962 221 0.085
aromatic compound catabolic process GO:0019439 286 0.085
renal system development GO:0072001 225 0.084
wnt signaling pathway GO:0016055 188 0.083
response to peptide hormone GO:0043434 127 0.082
positive regulation of leukocyte differentiation GO:1902107 86 0.080
peptidyl tyrosine phosphorylation GO:0018108 143 0.080
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.079
intracellular protein transport GO:0006886 204 0.079
Human Mouse
formation of radial glial scaffolds GO:0021943 4 0.077
regulation of spindle organization GO:0090224 2 0.077
Mouse
embryonic heart tube development GO:0035050 65 0.077
Human Zebrafish
cation transport GO:0006812 399 0.077
lymphocyte differentiation GO:0030098 242 0.075
regulation of microtubule based process GO:0032886 52 0.075
Mouse
gastrulation with mouth forming second GO:0001702 29 0.075
positive regulation of neuron differentiation GO:0045666 141 0.075
phosphatidylinositol mediated signaling GO:0048015 41 0.074
negative regulation of osteoblast differentiation GO:0045668 30 0.074
regulation of protein kinase activity GO:0045859 232 0.074
Human
regulation of extent of cell growth GO:0061387 52 0.074
nephron epithelium morphogenesis GO:0072088 68 0.073
Human
negative regulation of leukocyte differentiation GO:1902106 51 0.073
regulation of cell cycle process GO:0010564 160 0.072
Human Mouse
primary neural tube formation GO:0014020 95 0.071
regulation of protein import into nucleus GO:0042306 52 0.070
Human Mouse
erk1 and erk2 cascade GO:0070371 77 0.069
endoderm development GO:0007492 45 0.069
regulation of cell activation GO:0050865 289 0.069
regulation of microtubule cytoskeleton organization GO:0070507 37 0.069
Mouse
regulation of astrocyte differentiation GO:0048710 20 0.069
appendage morphogenesis GO:0035107 149 0.069
leukocyte migration GO:0050900 124 0.069
lung development GO:0030324 164 0.069
skin development GO:0043588 220 0.068
response to insulin GO:0032868 100 0.068
epidermis development GO:0008544 187 0.067
positive regulation of cellular catabolic process GO:0031331 148 0.067
neuron apoptotic process GO:0051402 142 0.066
positive regulation of vasoconstriction GO:0045907 4 0.066
purine containing compound metabolic process GO:0072521 311 0.066
positive regulation of protein modification process GO:0031401 299 0.065
Human
axon ensheathment GO:0008366 76 0.065
defense response to bacterium GO:0042742 119 0.065
positive regulation of cell adhesion GO:0045785 80 0.065
response to light stimulus GO:0009416 135 0.065
regulation of cytoplasmic transport GO:1903649 112 0.065
Human Mouse
regulation of mitotic cell cycle GO:0007346 126 0.063
Human Mouse
nephron epithelium development GO:0072009 92 0.063
Human Zebrafish
actin cytoskeleton organization GO:0030036 220 0.063
odontogenesis GO:0042476 78 0.063
telencephalon development GO:0021537 186 0.063
cytoplasmic transport GO:0016482 234 0.063
embryonic skeletal system development GO:0048706 120 0.062
regulation of protein serine threonine kinase activity GO:0071900 157 0.062
Human
metanephros development GO:0001656 79 0.062
Human
metal ion homeostasis GO:0055065 189 0.061
positive regulation of programmed cell death GO:0043068 218 0.061
bmp signaling pathway GO:0030509 93 0.060
divalent inorganic cation homeostasis GO:0072507 138 0.060
negative regulation of neuron death GO:1901215 98 0.060
regulation of defense response GO:0031347 233 0.060
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.059
cellular ion homeostasis GO:0006873 165 0.059
peptidyl amino acid modification GO:0018193 336 0.059
Mouse
gliogenesis GO:0042063 141 0.058
response to oxidative stress GO:0006979 123 0.058
respiratory system development GO:0060541 190 0.058
myelination GO:0042552 74 0.058
regulation of ras protein signal transduction GO:0046578 114 0.058
skeletal muscle organ development GO:0060538 163 0.057
t cell differentiation in thymus GO:0033077 77 0.057
rho protein signal transduction GO:0007266 32 0.057
regulation of metal ion transport GO:0010959 106 0.056
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.056
release of sequestered calcium ion into cytosol GO:0051209 42 0.055
neural tube closure GO:0001843 90 0.054
cellular amine metabolic process GO:0044106 44 0.054
midgut development GO:0007494 4 0.054
negative regulation of calcium ion transmembrane transport GO:1903170 1 0.052
extrinsic apoptotic signaling pathway GO:0097191 126 0.052
pallium development GO:0021543 120 0.052
negative regulation of neuron apoptotic process GO:0043524 92 0.052
auditory receptor cell differentiation GO:0042491 37 0.051
digestive tract development GO:0048565 190 0.051
protein localization to organelle GO:0033365 185 0.051
Human Mouse
regulation of inflammatory response GO:0050727 147 0.051
dna metabolic process GO:0006259 303 0.051
response to organonitrogen compound GO:0010243 246 0.051
cell matrix adhesion GO:0007160 68 0.050
tissue migration GO:0090130 68 0.050
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.050
cytokine production GO:0001816 319 0.049
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.049
hair cycle GO:0042633 90 0.048
regulation of glial cell differentiation GO:0045685 41 0.048
regulation of reproductive process GO:2000241 66 0.047
Mouse
response to ph GO:0009268 14 0.047
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
retinal ganglion cell axon guidance GO:0031290 18 0.047
positive regulation of mapk cascade GO:0043410 170 0.047
negative regulation of blood vessel morphogenesis GO:2000181 25 0.047
regulation of neuron apoptotic process GO:0043523 122 0.046
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.046
bone development GO:0060348 120 0.046
molting cycle GO:0042303 90 0.046
cation homeostasis GO:0055080 212 0.045
artery development GO:0060840 53 0.045
Human
cell type specific apoptotic process GO:0097285 268 0.045
b cell activation GO:0042113 161 0.045
lymphocyte homeostasis GO:0002260 64 0.045
cytokine production involved in immune response GO:0002367 34 0.045
stem cell differentiation GO:0048863 268 0.045
lens development in camera type eye GO:0002088 62 0.044
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.044
transmission of nerve impulse GO:0019226 76 0.044
potassium ion transmembrane transport GO:0071805 43 0.044
myeloid cell homeostasis GO:0002262 114 0.044
regulation of multi organism process GO:0043900 111 0.044
Mouse
venous blood vessel development GO:0060841 13 0.043
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
axonogenesis GO:0007409 274 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.043
posttranscriptional regulation of gene expression GO:0010608 155 0.043
regulation of kinase activity GO:0043549 249 0.043
Human
detection of chemical stimulus involved in sensory perception GO:0050907 10 0.043
Mouse
t cell activation GO:0042110 289 0.043
peptidyl tyrosine modification GO:0018212 145 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.043
jak stat cascade GO:0007259 42 0.043
chemotaxis GO:0006935 247 0.043
determination of digestive tract left right asymmetry GO:0071907 1 0.042
establishment or maintenance of cell polarity GO:0007163 86 0.042
Mouse
cation transmembrane transport GO:0098655 266 0.042
nuclear division GO:0000280 158 0.042
regulation of vesicle mediated transport GO:0060627 139 0.042
Mouse
embryonic digit morphogenesis GO:0042733 56 0.041
nuclear import GO:0051170 95 0.041
Human Mouse
protein processing GO:0016485 163 0.041
brain morphogenesis GO:0048854 32 0.041
negative regulation of defense response GO:0031348 77 0.041
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.040
Human
cell chemotaxis GO:0060326 81 0.040
intracellular receptor signaling pathway GO:0030522 74 0.040
t cell apoptotic process GO:0070231 39 0.040
norepinephrine transport GO:0015874 2 0.040
positive regulation of epithelial cell migration GO:0010634 19 0.039
negative regulation of ion transport GO:0043271 28 0.039
camera type eye development GO:0043010 266 0.039
regulation of lymphocyte activation GO:0051249 240 0.039
cellular calcium ion homeostasis GO:0006874 119 0.039
gonad development GO:0008406 141 0.039
regulation of cell growth GO:0001558 91 0.039
muscle cell migration GO:0014812 19 0.039
branching involved in ureteric bud morphogenesis GO:0001658 56 0.039
Human
maintenance of location GO:0051235 89 0.039
adult behavior GO:0030534 135 0.039
mesoderm development GO:0007498 100 0.039
neural tube patterning GO:0021532 43 0.038
inflammatory response GO:0006954 244 0.038
cellular amino acid metabolic process GO:0006520 103 0.038
protein localization to plasma membrane GO:0072659 57 0.038
blood vessel morphogenesis GO:0048514 285 0.038
Human
dendritic cell differentiation GO:0097028 26 0.038
membrane organization GO:0061024 245 0.038
negative regulation of neuron differentiation GO:0045665 101 0.037
establishment of protein localization to organelle GO:0072594 118 0.037
Human Mouse
hepaticobiliary system development GO:0061008 67 0.037
protein targeting GO:0006605 143 0.037
Human Mouse
divalent inorganic cation transport GO:0072511 178 0.036
regulation of blood pressure GO:0008217 93 0.036
organelle fission GO:0048285 170 0.036
endothelial cell migration GO:0043542 44 0.036
regulation of erk1 and erk2 cascade GO:0070372 71 0.036
cerebellum morphogenesis GO:0021587 42 0.036
regulation of protein kinase b signaling GO:0051896 56 0.035
embryonic hemopoiesis GO:0035162 23 0.035
positive regulation of cell development GO:0010720 237 0.035
somatic stem cell maintenance GO:0035019 47 0.035
regulation of protein catabolic process GO:0042176 108 0.035
Mouse
response to acid chemical GO:0001101 111 0.035
Human
multicellular organismal aging GO:0010259 24 0.035
regulation of mapk cascade GO:0043408 248 0.035
transmembrane transport GO:0055085 412 0.035
extracellular matrix dependent thymocyte migration GO:0072680 1 0.035
sperm ejaculation GO:0042713 1 0.035
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.035
nucleotide catabolic process GO:0009166 217 0.034
cell recognition GO:0008037 83 0.034
multicellular organismal signaling GO:0035637 91 0.034
stem cell maintenance GO:0019827 130 0.034
cytosolic calcium ion homeostasis GO:0051480 70 0.034
negative regulation of molecular function GO:0044092 258 0.034
regulation of neuron death GO:1901214 134 0.034
neuronal action potential GO:0019228 54 0.034
regulation of neuron projection development GO:0010975 169 0.034
ribose phosphate metabolic process GO:0019693 291 0.034
kidney morphogenesis GO:0060993 83 0.034
Human Zebrafish
negative regulation of phosphorylation GO:0042326 166 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.033
regulation of epithelial cell migration GO:0010632 35 0.033
negative regulation of cell development GO:0010721 169 0.033
regulation of ossification GO:0030278 112 0.033
protein localization to membrane GO:0072657 108 0.033
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.033
trabecula morphogenesis GO:0061383 40 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
regulation of endodermal cell fate specification GO:0042663 2 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
nitrogen compound transport GO:0071705 271 0.032
positive regulation of protein localization to nucleus GO:1900182 30 0.032
positive regulation of t cell differentiation GO:0045582 52 0.032
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.032
regulation of reactive oxygen species metabolic process GO:2000377 40 0.032
acute inflammatory response GO:0002526 41 0.032
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.031
regulation of osteoblast differentiation GO:0045667 67 0.031
visual learning GO:0008542 44 0.031
muscle cell differentiation GO:0042692 261 0.031
exocytosis GO:0006887 121 0.031
Mouse
ossification GO:0001503 216 0.031
regulation of innate immune response GO:0045088 91 0.031
cellular response to peptide hormone stimulus GO:0071375 92 0.031
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
calcium ion transmembrane transport GO:0070588 85 0.031
metanephric epithelium development GO:0072207 21 0.031
Human
regulation of hydrolase activity GO:0051336 246 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
cell growth GO:0016049 130 0.030
nucleotide metabolic process GO:0009117 332 0.030
potassium ion transport GO:0006813 52 0.030
morphogenesis of embryonic epithelium GO:0016331 159 0.030
ear development GO:0043583 200 0.030
circulatory system process GO:0003013 197 0.030
Zebrafish
mitotic nuclear division GO:0007067 48 0.030
hematopoietic stem cell migration GO:0035701 1 0.030
regulation of cellular component biogenesis GO:0044087 181 0.029
positive regulation of cytoplasmic transport GO:1903651 40 0.029
endocytosis GO:0006897 168 0.029
cellular response to dna damage stimulus GO:0006974 207 0.029
regulation of camp metabolic process GO:0030814 30 0.029
t cell differentiation GO:0030217 174 0.029
positive regulation of inflammatory response GO:0050729 47 0.029
ras protein signal transduction GO:0007265 77 0.029
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.028
cellular chemical homeostasis GO:0055082 215 0.028
metanephric loop of henle development GO:0072236 4 0.028
Human
response to decreased oxygen levels GO:0036293 59 0.028
metanephric tubule development GO:0072170 18 0.028
Human
mechanoreceptor differentiation GO:0042490 67 0.028
negative regulation of cell activation GO:0050866 111 0.028
regulation of axon extension GO:0030516 43 0.028
reproductive behavior GO:0019098 32 0.028
Worm
regulation of anatomical structure size GO:0090066 178 0.028
microtubule cytoskeleton organization GO:0000226 157 0.028
Mouse
positive regulation of protein import into nucleus GO:0042307 26 0.027
regulation of calcium ion dependent exocytosis GO:0017158 16 0.027
Mouse
cellular response to starvation GO:0009267 57 0.027
extracellular matrix organization GO:0030198 147 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
Mouse
positive regulation of behavior GO:0048520 40 0.027
multi organism reproductive behavior GO:0044705 29 0.027
Worm
regulation of response to wounding GO:1903034 189 0.027
oogenesis GO:0048477 56 0.027
plasma membrane organization GO:0007009 90 0.027
single organism cell adhesion GO:0098602 156 0.027
Mouse
regulation of cellular catabolic process GO:0031329 242 0.027
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.027
catecholamine secretion GO:0050432 15 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.027
regulation of peptidase activity GO:0052547 96 0.027
fatty acid biosynthetic process GO:0006633 41 0.026
regulation of cytokine production GO:0001817 266 0.026
divalent metal ion transport GO:0070838 172 0.026
endocrine system development GO:0035270 98 0.026
maternal placenta development GO:0001893 20 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
cerebral cortex radially oriented cell migration GO:0021799 31 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
apoptotic signaling pathway GO:0097190 306 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
response to nutrient levels GO:0031667 109 0.026
somatic cell dna recombination GO:0016444 51 0.025
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.025
astrocyte differentiation GO:0048708 43 0.025
positive regulation of protein transport GO:0051222 93 0.025
regulation of intracellular protein transport GO:0033157 82 0.025
Human Mouse
membrane biogenesis GO:0044091 12 0.025
mitotic cytokinesis GO:0000281 4 0.025
adult locomotory behavior GO:0008344 91 0.025
mucopolysaccharide metabolic process GO:1903510 25 0.025
tissue homeostasis GO:0001894 115 0.025
collecting duct development GO:0072044 11 0.025
Human
phagocytosis GO:0006909 66 0.025
cellular divalent inorganic cation homeostasis GO:0072503 127 0.025
activation of mapk activity involved in innate immune response GO:0035419 2 0.025
determination of left right asymmetry in nervous system GO:0035545 1 0.025
tissue remodeling GO:0048771 102 0.025
muscle tissue development GO:0060537 308 0.025
Human
endomembrane system organization GO:0010256 147 0.025
ribonucleotide metabolic process GO:0009259 291 0.024
positive regulation of neuron projection development GO:0010976 79 0.024
regulation of cytoskeleton organization GO:0051493 122 0.024
Mouse
positive regulation of innate immune response GO:0045089 80 0.024
positive regulation of smad protein import into nucleus GO:0060391 2 0.024
spindle organization GO:0007051 28 0.024
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.024
lymph vessel morphogenesis GO:0036303 11 0.024
Zebrafish Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.024
sensory perception of chemical stimulus GO:0007606 51 0.024
Mouse
negative regulation of cell cycle phase transition GO:1901988 48 0.024
Human
somite specification GO:0001757 4 0.024
anatomical structure homeostasis GO:0060249 145 0.024
regulation of nucleocytoplasmic transport GO:0046822 73 0.024
Human Mouse
single fertilization GO:0007338 82 0.024
Mouse
forebrain development GO:0030900 302 0.024
neuron death GO:0070997 154 0.024
response to fluid shear stress GO:0034405 7 0.024
production of molecular mediator of immune response GO:0002440 103 0.024
g1 s transition of mitotic cell cycle GO:0000082 57 0.024
Human
regulation of cell size GO:0008361 72 0.024
leukocyte chemotaxis GO:0030595 69 0.024
keratinocyte differentiation GO:0030216 48 0.023
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.023
hindbrain radial glia guided cell migration GO:0021932 12 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.023
calcium ion homeostasis GO:0055074 127 0.023
cellular lipid metabolic process GO:0044255 323 0.023
peripheral nervous system development GO:0007422 53 0.023
positive regulation of cell activation GO:0050867 158 0.023
regulation of t cell activation GO:0050863 170 0.023
protein import into nucleus GO:0006606 95 0.023
Human Mouse
cellular response to insulin stimulus GO:0032869 78 0.023
regulation of eosinophil migration GO:2000416 2 0.023

Pkd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nephronophthisis DOID:12712 0 0.225
disease of cellular proliferation DOID:14566 0 0.071
immune system disease DOID:2914 0 0.043
normocytic anemia DOID:720 0 0.043
disease of anatomical entity DOID:7 0 0.043
anemia DOID:2355 0 0.043
hematopoietic system disease DOID:74 0 0.043
retinal disease DOID:5679 0 0.039
sensory system disease DOID:0050155 0 0.039
eye and adnexa disease DOID:1492 0 0.039
nervous system disease DOID:863 0 0.039
eye disease DOID:5614 0 0.039
musculoskeletal system disease DOID:17 0 0.033
connective tissue disease DOID:65 0 0.033
cancer DOID:162 0 0.024
organ system cancer DOID:0050686 0 0.024