Mus musculus

27 known processes

Pkm2

pyruvate kinase, muscle

(Aliases: Pk3,Pk-2,Pk-3,AA414905,AL024424,AL024370)

Pkm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate catabolic process GO:0016052 32 1.000
glycolytic process GO:0006096 20 1.000
pyruvate metabolic process GO:0006090 28 0.999
hexose catabolic process GO:0019320 3 0.996
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.972
generation of precursor metabolites and energy GO:0006091 103 0.943
pentose phosphate shunt GO:0006098 2 0.900
nadph regeneration GO:0006740 2 0.889
monocarboxylic acid metabolic process GO:0032787 191 0.829
hexose metabolic process GO:0019318 98 0.794
glucose catabolic process GO:0006007 3 0.777
carbohydrate phosphorylation GO:0046835 15 0.748
carbohydrate metabolic process GO:0005975 230 0.747
lactate biosynthetic process GO:0019249 4 0.727
carbohydrate derivative biosynthetic process GO:1901137 183 0.712
atp metabolic process GO:0046034 75 0.706
myosin filament organization GO:0031033 3 0.645
Worm
nucleoside metabolic process GO:0009116 246 0.602
sperm motility GO:0030317 47 0.585
purine nucleoside biosynthetic process GO:0042451 19 0.581
purine nucleoside monophosphate biosynthetic process GO:0009127 9 0.460
ribose phosphate biosynthetic process GO:0046390 59 0.434
nucleotide metabolic process GO:0009117 332 0.430
oxidation reduction process GO:0055114 342 0.429
nucleobase containing small molecule metabolic process GO:0055086 352 0.418
purine nucleotide biosynthetic process GO:0006164 65 0.404
monosaccharide metabolic process GO:0005996 106 0.402
purine containing compound biosynthetic process GO:0072522 70 0.365
nucleoside phosphate metabolic process GO:0006753 338 0.364
regulation of coenzyme metabolic process GO:0051196 4 0.360
mitotic cell cycle GO:0000278 195 0.352
nitrogen compound transport GO:0071705 271 0.350
cellular aldehyde metabolic process GO:0006081 12 0.343
purine containing compound metabolic process GO:0072521 311 0.340
maintenance of location GO:0051235 89 0.331
insulin secretion GO:0030073 89 0.313
regulation of hormone levels GO:0010817 211 0.310
glucose homeostasis GO:0042593 128 0.308
nucleoside phosphate biosynthetic process GO:1901293 79 0.300
negative regulation of cellular protein metabolic process GO:0032269 247 0.298
purine ribonucleoside metabolic process GO:0046128 241 0.286
positive regulation of hormone secretion GO:0046887 38 0.246
nucleoside monophosphate metabolic process GO:0009123 85 0.245
purine ribonucleotide metabolic process GO:0009150 290 0.230
cellular homeostasis GO:0019725 240 0.225
positive regulation of programmed cell death GO:0043068 218 0.207
nadp metabolic process GO:0006739 6 0.206
purine nucleoside monophosphate metabolic process GO:0009126 81 0.200
positive regulation of peptide secretion GO:0002793 33 0.199
ribonucleoside biosynthetic process GO:0042455 21 0.196
negative regulation of peptide secretion GO:0002792 16 0.189
organic hydroxy compound biosynthetic process GO:1901617 77 0.185
regulation of translation GO:0006417 71 0.182
negative regulation of secretion GO:0051048 61 0.169
regulation of peptide transport GO:0090087 91 0.166
ribonucleoside monophosphate metabolic process GO:0009161 80 0.163
nucleoside triphosphate metabolic process GO:0009141 230 0.162
regulation of cell cycle GO:0051726 281 0.162
mesoderm formation GO:0001707 62 0.157
oxidoreduction coenzyme metabolic process GO:0006733 16 0.156
purine nucleotide metabolic process GO:0006163 302 0.155
substantia nigra development GO:0021762 2 0.152
response to organonitrogen compound GO:0010243 246 0.150
nucleoside biosynthetic process GO:0009163 21 0.148
response to decreased oxygen levels GO:0036293 59 0.146
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.145
cellular amino acid metabolic process GO:0006520 103 0.144
positive regulation of apoptotic process GO:0043065 217 0.143
purine nucleoside triphosphate biosynthetic process GO:0009145 7 0.140
anatomical structure homeostasis GO:0060249 145 0.137
pigmentation GO:0043473 71 0.134
myosin filament assembly GO:0031034 2 0.124
Worm
striated muscle myosin thick filament assembly GO:0071688 1 0.123
Worm
glucose metabolic process GO:0006006 92 0.122
cellular response to external stimulus GO:0071496 88 0.120
cellular response to dna damage stimulus GO:0006974 207 0.117
purine nucleoside triphosphate metabolic process GO:0009144 226 0.114
ribose phosphate metabolic process GO:0019693 291 0.113
purine ribonucleotide biosynthetic process GO:0009152 59 0.112
ribonucleoside triphosphate metabolic process GO:0009199 220 0.112
formation of primary germ layer GO:0001704 77 0.110
purine nucleoside metabolic process GO:0042278 241 0.108
glycosyl compound biosynthetic process GO:1901659 21 0.107
cellular amide metabolic process GO:0043603 58 0.107
heterocycle catabolic process GO:0046700 280 0.106
cation transport GO:0006812 399 0.104
cytoplasmic transport GO:0016482 234 0.104
positive regulation of growth GO:0045927 104 0.103
negative regulation of protein metabolic process GO:0051248 282 0.103
peptide transport GO:0015833 133 0.102
regulation of secretion GO:0051046 274 0.101
organic hydroxy compound metabolic process GO:1901615 203 0.101
muscle contraction GO:0006936 101 0.101
response to inorganic substance GO:0010035 96 0.101
carboxylic acid biosynthetic process GO:0046394 86 0.097
amide transport GO:0042886 138 0.097
hormone secretion GO:0046879 128 0.096
response to heat GO:0009408 27 0.087
ras protein signal transduction GO:0007265 77 0.085
regulation of cofactor metabolic process GO:0051193 5 0.084
regulation of cell shape GO:0008360 39 0.082
response to organic cyclic compound GO:0014070 198 0.082
somitogenesis GO:0001756 69 0.081
fertilization GO:0009566 127 0.078
dna integrity checkpoint GO:0031570 28 0.077
protein targeting GO:0006605 143 0.077
regulation of peptide secretion GO:0002791 77 0.075
cellular carbohydrate catabolic process GO:0044275 15 0.073
homeostasis of number of cells GO:0048872 210 0.073
fructose metabolic process GO:0006000 1 0.072
negative regulation of cell cycle phase transition GO:1901988 48 0.070
carbohydrate biosynthetic process GO:0016051 74 0.069
regulation of ion transport GO:0043269 215 0.066
cellular component assembly involved in morphogenesis GO:0010927 139 0.066
Worm
covalent chromatin modification GO:0016569 163 0.066
cell type specific apoptotic process GO:0097285 268 0.064
response to nicotine GO:0035094 6 0.062
mitotic cell cycle process GO:1903047 159 0.061
mitotic cell cycle checkpoint GO:0007093 31 0.061
dicarboxylic acid biosynthetic process GO:0043650 5 0.061
lipid localization GO:0010876 126 0.060
organic anion transport GO:0015711 137 0.060
protein complex disassembly GO:0043241 40 0.058
cellular amine metabolic process GO:0044106 44 0.057
muscle cell development GO:0055001 133 0.057
Worm
mesoderm development GO:0007498 100 0.056
regulation of cellular catabolic process GO:0031329 242 0.056
developmental maturation GO:0021700 193 0.056
calcium ion transport GO:0006816 159 0.056
protein modification by small protein conjugation or removal GO:0070647 207 0.055
multicellular organism growth GO:0035264 161 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.055
neuron death GO:0070997 154 0.055
regulation of secretion by cell GO:1903530 249 0.054
cellular ion homeostasis GO:0006873 165 0.054
regulation of mitotic cell cycle phase transition GO:1901990 73 0.054
response to steroid hormone GO:0048545 56 0.053
myotube differentiation GO:0014902 105 0.053
aromatic compound catabolic process GO:0019439 286 0.052
regulation of hydrolase activity GO:0051336 246 0.052
regulation of cell cycle process GO:0010564 160 0.051
peptide hormone secretion GO:0030072 109 0.050
regulation of neuron death GO:1901214 134 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.050
regulation of mitotic cell cycle GO:0007346 126 0.050
purine ribonucleoside monophosphate biosynthetic process GO:0009168 9 0.050
protein catabolic process GO:0030163 221 0.050
small molecule catabolic process GO:0044282 71 0.049
response to lipopolysaccharide GO:0032496 128 0.049
intracellular protein transport GO:0006886 204 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
regulation of protein localization GO:0032880 231 0.047
4 hydroxyproline metabolic process GO:0019471 5 0.047
mesoderm morphogenesis GO:0048332 64 0.047
organonitrogen compound biosynthetic process GO:1901566 192 0.047
regulation of glucose metabolic process GO:0010906 60 0.046
protein modification by small protein conjugation GO:0032446 187 0.046
monosaccharide biosynthetic process GO:0046364 44 0.045
nuclear transport GO:0051169 139 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.045
divalent inorganic cation transport GO:0072511 178 0.045
energy derivation by oxidation of organic compounds GO:0015980 77 0.045
positive regulation of peptide hormone secretion GO:0090277 31 0.044
protein oligomerization GO:0051259 67 0.044
apoptotic signaling pathway GO:0097190 306 0.044
axonogenesis GO:0007409 274 0.044
regulation of intracellular transport GO:0032386 159 0.044
cation homeostasis GO:0055080 212 0.043
regulation of metal ion transport GO:0010959 106 0.043
macromolecule catabolic process GO:0009057 281 0.043
actin polymerization or depolymerization GO:0008154 54 0.042
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.042
protein ubiquitination GO:0016567 171 0.042
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.042
digestive tract morphogenesis GO:0048546 147 0.042
organic acid transport GO:0015849 101 0.041
striated muscle contraction GO:0006941 45 0.041
positive regulation of cell death GO:0010942 224 0.041
response to oxidative stress GO:0006979 123 0.040
citrulline metabolic process GO:0000052 3 0.040
dna repair GO:0006281 107 0.039
cellular carbohydrate metabolic process GO:0044262 119 0.039
regulation of transposition GO:0010528 2 0.039
cytoskeleton dependent intracellular transport GO:0030705 50 0.039
gastrulation GO:0007369 116 0.038
cellular metal ion homeostasis GO:0006875 151 0.038
microtubule based transport GO:0010970 50 0.038
negative regulation of neuron death GO:1901215 98 0.037
ribonucleoside triphosphate biosynthetic process GO:0009201 6 0.037
cell adhesion GO:0007155 329 0.037
multi organism behavior GO:0051705 62 0.036
transmembrane transport GO:0055085 412 0.036
peptide secretion GO:0002790 114 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
muscle system process GO:0003012 141 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
positive regulation of insulin secretion GO:0032024 26 0.036
regulation of proteolysis GO:0030162 164 0.036
regulation of cell cycle phase transition GO:1901987 77 0.036
cellular response to organonitrogen compound GO:0071417 145 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
divalent metal ion transport GO:0070838 172 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
placenta development GO:0001890 140 0.035
nucleoside monophosphate biosynthetic process GO:0009124 12 0.034
epithelial tube morphogenesis GO:0060562 303 0.034
actin filament depolymerization GO:0030042 15 0.034
cell maturation GO:0048469 127 0.033
regulation of glycolytic process GO:0006110 10 0.033
retina development in camera type eye GO:0060041 119 0.033
axon guidance GO:0007411 141 0.033
muscle cell differentiation GO:0042692 261 0.033
Worm
gonad development GO:0008406 141 0.032
dephosphorylation GO:0016311 129 0.032
pyridine nucleotide metabolic process GO:0019362 12 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
cellular modified amino acid metabolic process GO:0006575 63 0.031
cellular response to extracellular stimulus GO:0031668 81 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
skin development GO:0043588 220 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
regulation of synaptic plasticity GO:0048167 87 0.031
anion transport GO:0006820 177 0.030
endomembrane system organization GO:0010256 147 0.030
actin filament polymerization GO:0030041 44 0.030
genitalia development GO:0048806 37 0.030
spermatogenesis GO:0007283 284 0.029
metal ion homeostasis GO:0055065 189 0.029
epithelial cell development GO:0002064 159 0.029
sensory system development GO:0048880 3 0.029
negative regulation of cell cycle process GO:0010948 69 0.029
cellular response to monosaccharide stimulus GO:0071326 47 0.029
sequestering of calcium ion GO:0051208 18 0.029
response to metal ion GO:0010038 47 0.029
response to radiation GO:0009314 165 0.028
zymogen activation GO:0031638 41 0.028
wnt signaling pathway GO:0016055 188 0.028
protein localization to organelle GO:0033365 185 0.027
negative regulation of translation GO:0017148 22 0.027
cellular polysaccharide metabolic process GO:0044264 38 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
protein depolymerization GO:0051261 34 0.027
syncytium formation GO:0006949 43 0.027
positive regulation of secretion by cell GO:1903532 114 0.027
neural tube formation GO:0001841 108 0.027
g protein coupled receptor signaling pathway GO:0007186 243 0.027
pyridine containing compound metabolic process GO:0072524 14 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
histone modification GO:0016570 159 0.026
oocyte anterior posterior axis specification GO:0007314 2 0.026
regulation of nucleocytoplasmic transport GO:0046822 73 0.026
carboxylic acid transport GO:0046942 100 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
cell division GO:0051301 120 0.026
alpha amino acid metabolic process GO:1901605 59 0.026
negative regulation of mitotic cell cycle GO:0045930 58 0.026
glutamine family amino acid biosynthetic process GO:0009084 2 0.026
dna metabolic process GO:0006259 303 0.025
peptidyl proline hydroxylation GO:0019511 3 0.025
gluconeogenesis GO:0006094 39 0.025
regulation of hormone secretion GO:0046883 88 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
regulation of wnt signaling pathway GO:0030111 123 0.025
regulation of calcium ion transport GO:0051924 69 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
monocarboxylic acid biosynthetic process GO:0072330 61 0.025
regulation of calcium ion transport into cytosol GO:0010522 31 0.025
synaptic transmission GO:0007268 329 0.025
regulation of neuron apoptotic process GO:0043523 122 0.025
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.025
response to light stimulus GO:0009416 135 0.024
glucan metabolic process GO:0044042 32 0.024
female gamete generation GO:0007292 74 0.024
cofactor metabolic process GO:0051186 80 0.024
learning GO:0007612 98 0.024
locomotory behavior GO:0007626 195 0.024
establishment of vesicle localization GO:0051650 81 0.024
negative regulation of insulin secretion GO:0046676 14 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
lateral line system development GO:0048925 1 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
cellular ketone metabolic process GO:0042180 84 0.023
cell fate commitment GO:0045165 210 0.023
sequestering of metal ion GO:0051238 19 0.023
forebrain development GO:0030900 302 0.023
sensory perception GO:0007600 245 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
amine metabolic process GO:0009308 45 0.023
establishment of protein localization to organelle GO:0072594 118 0.023
regulation of protein transport GO:0051223 163 0.023
translation GO:0006412 93 0.022
glutamate biosynthetic process GO:0006537 2 0.022
protein localization to nucleus GO:0034504 121 0.022
cognition GO:0050890 149 0.022
regulation of membrane potential GO:0042391 192 0.022
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.022
positive regulation of secretion GO:0051047 130 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
peptidyl amino acid modification GO:0018193 336 0.022
negative regulation of hormone secretion GO:0046888 20 0.022
necrotic cell death GO:0070265 30 0.022
mitotic g2 dna damage checkpoint GO:0007095 8 0.021
activation of cysteine type endopeptidase activity GO:0097202 27 0.021
positive regulation of hydrolase activity GO:0051345 148 0.021
pole plasm assembly GO:0007315 2 0.021
reproductive behavior GO:0019098 32 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
regulation of peptide hormone secretion GO:0090276 75 0.021
tissue migration GO:0090130 68 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
protein processing GO:0016485 163 0.021
compound eye development GO:0048749 1 0.021
response to estrogen GO:0043627 24 0.021
meiotic nuclear division GO:0007126 115 0.021
heart morphogenesis GO:0003007 178 0.021
positive regulation of nervous system development GO:0051962 221 0.021
midbrain development GO:0030901 35 0.021
negative regulation of peptide hormone secretion GO:0090278 16 0.021
positive regulation of calcium ion transport GO:0051928 27 0.021
cell redox homeostasis GO:0045454 6 0.020
negative regulation of neuron apoptotic process GO:0043524 92 0.020
cellular response to lipid GO:0071396 145 0.020
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
maintenance of location in cell GO:0051651 24 0.020
learning or memory GO:0007611 148 0.020
striated muscle tissue development GO:0014706 293 0.020
mapk cascade GO:0000165 281 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
multi multicellular organism process GO:0044706 109 0.019
response to insulin GO:0032868 100 0.019
positive regulation of chromosome organization GO:2001252 33 0.019
sensory organ morphogenesis GO:0090596 242 0.019
response to hypoxia GO:0001666 58 0.019
protein localization to mitochondrion GO:0070585 15 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
organophosphate catabolic process GO:0046434 232 0.019
regulation of chromosome organization GO:0033044 83 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
photoreceptor cell development GO:0042461 40 0.019
regulation of actin nucleation GO:0051125 4 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
regulation of actin filament depolymerization GO:0030834 13 0.018
myofibril assembly GO:0030239 34 0.018
Worm
chromatin modification GO:0016568 187 0.018
positive regulation of protein modification process GO:0031401 299 0.018
regulation of response to wounding GO:1903034 189 0.018
translesion synthesis GO:0019985 1 0.018
regulation of protein depolymerization GO:1901879 26 0.018
cellular chemical homeostasis GO:0055082 215 0.018
positive regulation of organelle organization GO:0010638 128 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
positive regulation of necrotic cell death GO:0010940 1 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
cellular response to osmotic stress GO:0071470 7 0.018
multicellular organismal aging GO:0010259 24 0.018
Worm
cellular macromolecule catabolic process GO:0044265 206 0.017
regulation of ion transmembrane transporter activity GO:0032412 54 0.017
hexose biosynthetic process GO:0019319 39 0.017
cell cycle checkpoint GO:0000075 47 0.017
macromolecular complex disassembly GO:0032984 43 0.017
receptor mediated endocytosis GO:0006898 51 0.017
response to peptide hormone GO:0043434 127 0.017
organelle localization GO:0051640 179 0.017
renal system development GO:0072001 225 0.017
carbohydrate homeostasis GO:0033500 128 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
glycogen metabolic process GO:0005977 32 0.017
positive regulation of cell activation GO:0050867 158 0.017
asymmetric neuroblast division GO:0055059 1 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
dicarboxylic acid transport GO:0006835 29 0.017
single organism cell adhesion GO:0098602 156 0.016
regulation of body fluid levels GO:0050878 162 0.016
regulation of transporter activity GO:0032409 57 0.016
exocytosis GO:0006887 121 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
syncytium formation by plasma membrane fusion GO:0000768 42 0.016
cation transmembrane transport GO:0098655 266 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
rho protein signal transduction GO:0007266 32 0.016
nuclear import GO:0051170 95 0.016
maternal determination of anterior posterior axis embryo GO:0008358 2 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.016
meiotic cell cycle GO:0051321 122 0.016
negative regulation of cell development GO:0010721 169 0.016
response to acid chemical GO:0001101 111 0.016
cellular response to acid chemical GO:0071229 68 0.016
regulation of cell motility GO:2000145 236 0.016
microtubule based process GO:0007017 236 0.016
regulation of carbohydrate metabolic process GO:0006109 75 0.016
retrograde transport endosome to golgi GO:0042147 2 0.015
epidermis development GO:0008544 187 0.015
calcium ion homeostasis GO:0055074 127 0.015
establishment of organelle localization GO:0051656 122 0.015
hormone metabolic process GO:0042445 86 0.015
glucose import GO:0046323 32 0.015
regulation of cell adhesion GO:0030155 154 0.015
regionalization GO:0003002 337 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
regulation of homeostatic process GO:0032844 182 0.015
stem cell proliferation GO:0072089 117 0.015
amino acid transport GO:0006865 61 0.015
organelle fission GO:0048285 170 0.015
regulation of mapk cascade GO:0043408 248 0.015
leukocyte differentiation GO:0002521 342 0.015
cytosolic calcium ion homeostasis GO:0051480 70 0.015
response to extracellular stimulus GO:0009991 127 0.015
positive regulation of transmembrane transport GO:0034764 29 0.015
negative regulation of cell adhesion involved in substrate bound cell migration GO:0006933 3 0.015
cilium morphogenesis GO:0060271 102 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
mitochondrion organization GO:0007005 134 0.015
apoptotic mitochondrial changes GO:0008637 48 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
regulation of protein targeting GO:1903533 61 0.015
spindle localization GO:0051653 22 0.015
regulation of neuron differentiation GO:0045664 281 0.014
regulation of peptidase activity GO:0052547 96 0.014
respiratory tube development GO:0030323 167 0.014
nucleoside catabolic process GO:0009164 206 0.014
response to monosaccharide GO:0034284 67 0.014
protein maturation GO:0051604 176 0.014
calcium ion transmembrane transport GO:0070588 85 0.014
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.014
cerebellum development GO:0021549 77 0.014
tube formation GO:0035148 140 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
regulation of cell activation GO:0050865 289 0.014
circulatory system process GO:0003013 197 0.014
oocyte axis specification GO:0007309 2 0.014
telencephalon development GO:0021537 186 0.014
photoreceptor cell morphogenesis GO:0008594 3 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
male gamete generation GO:0048232 285 0.014
camera type eye development GO:0043010 266 0.014
fat cell differentiation GO:0045444 160 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
hatching GO:0035188 4 0.014
small molecule biosynthetic process GO:0044283 132 0.014
single fertilization GO:0007338 82 0.014
molting cycle GO:0042303 90 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
protein homotetramerization GO:0051289 12 0.014
asymmetric stem cell division GO:0098722 3 0.014
nucleotide biosynthetic process GO:0009165 78 0.014
nucleotide catabolic process GO:0009166 217 0.014
chromosome segregation GO:0007059 48 0.014
chromatin organization GO:0006325 206 0.014
cellular response to abiotic stimulus GO:0071214 56 0.013
wound healing GO:0042060 157 0.013
regulation of rho protein signal transduction GO:0035023 71 0.013
positive regulation of endopeptidase activity GO:0010950 43 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
energy reserve metabolic process GO:0006112 39 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of exit from mitosis GO:0007096 1 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
spermatid differentiation GO:0048515 115 0.013
neuronal action potential GO:0019228 54 0.013
positive regulation of kinase activity GO:0033674 155 0.013
neuron apoptotic process GO:0051402 142 0.013
mrna metabolic process GO:0016071 84 0.013
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.013
germ cell development GO:0007281 185 0.013
nuclear division GO:0000280 158 0.013
t cell proliferation GO:0042098 120 0.013
muscle tissue morphogenesis GO:0060415 53 0.013
regulation of transferase activity GO:0051338 263 0.013
coenzyme metabolic process GO:0006732 52 0.013
protein secretion GO:0009306 111 0.013
l amino acid transport GO:0015807 32 0.013
regulation of protein complex assembly GO:0043254 83 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
segmentation GO:0035282 93 0.012
primary neural tube formation GO:0014020 95 0.012
protein tetramerization GO:0051262 23 0.012
protein polyubiquitination GO:0000209 33 0.012

Pkm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.270
nervous system disease DOID:863 0 0.270
immune system disease DOID:2914 0 0.172
hematopoietic system disease DOID:74 0 0.161
disease of metabolism DOID:0014667 0 0.156
central nervous system disease DOID:331 0 0.095
neurodegenerative disease DOID:1289 0 0.078
anemia DOID:2355 0 0.069
carbohydrate metabolism disease DOID:0050013 0 0.029
acquired metabolic disease DOID:0060158 0 0.029
glucose metabolism disease DOID:4194 0 0.022
sensory system disease DOID:0050155 0 0.020