Mus musculus

15 known processes

Plaa

phospholipase A2, activating protein

(Aliases: PLA2P,AW208417,PLAP,D4Ertd618e,2410007N06,AI536418,AU018445,Ufd3)

Plaa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule polymerization or depolymerization GO:0031109 26 0.241
ubiquitin dependent protein catabolic process GO:0006511 129 0.239
Yeast
modification dependent macromolecule catabolic process GO:0043632 133 0.211
Yeast
protein modification by small protein conjugation or removal GO:0070647 207 0.173
regulation of microtubule based process GO:0032886 52 0.172
cellular response to misfolded protein GO:0071218 5 0.171
microtubule based process GO:0007017 236 0.157
cellular protein catabolic process GO:0044257 155 0.155
Yeast
negative regulation of cellular protein metabolic process GO:0032269 247 0.149
microtubule cytoskeleton organization GO:0000226 157 0.122
protein complex disassembly GO:0043241 40 0.121
protein modification by small protein conjugation GO:0032446 187 0.118
cellular response to starvation GO:0009267 57 0.116
chromatin modification GO:0016568 187 0.115
cellular macromolecule catabolic process GO:0044265 206 0.114
Yeast
regulation of receptor activity GO:0010469 41 0.113
chromatin organization GO:0006325 206 0.108
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.105
Yeast
protein processing GO:0016485 163 0.098
regulation of protein localization GO:0032880 231 0.098
modification dependent protein catabolic process GO:0019941 133 0.095
Yeast
regulation of protein maturation GO:1903317 96 0.095
cellular response to nutrient levels GO:0031669 64 0.095
protein ubiquitination GO:0016567 171 0.092
peptidyl amino acid modification GO:0018193 336 0.083
protein catabolic process GO:0030163 221 0.081
Yeast
cellular protein complex assembly GO:0043623 116 0.081
macromolecule catabolic process GO:0009057 281 0.077
Yeast
regulation of proteolysis GO:0030162 164 0.073
regulation of organelle organization GO:0033043 289 0.071
protein maturation GO:0051604 176 0.071
histone modification GO:0016570 159 0.071
protein depolymerization GO:0051261 34 0.069
response to misfolded protein GO:0051788 5 0.067
protein polyubiquitination GO:0000209 33 0.067
intracellular protein transport GO:0006886 204 0.067
positive regulation of cellular component biogenesis GO:0044089 94 0.066
negative regulation of protein processing GO:0010955 79 0.064
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.064
regulation of cell migration GO:0030334 219 0.062
regulation of protein processing GO:0070613 96 0.059
macroautophagy GO:0016236 21 0.058
peptidyl lysine modification GO:0018205 77 0.057
epithelium migration GO:0090132 63 0.056
cellular response to oxidative stress GO:0034599 76 0.056
negative regulation of cellular component organization GO:0051129 194 0.055
regulation of establishment of protein localization GO:0070201 181 0.053
response to extracellular stimulus GO:0009991 127 0.053
positive regulation of programmed cell death GO:0043068 218 0.053
macromolecular complex disassembly GO:0032984 43 0.052
covalent chromatin modification GO:0016569 163 0.051
positive regulation of cell death GO:0010942 224 0.050
microtubule depolymerization GO:0007019 15 0.049
macromolecule deacylation GO:0098732 37 0.049
negative regulation of proteolysis GO:0045861 74 0.049
response to inorganic substance GO:0010035 96 0.048
cellular response to external stimulus GO:0071496 88 0.047
regulation of protein complex assembly GO:0043254 83 0.046
regulation of cell motility GO:2000145 236 0.046
negative regulation of protein maturation GO:1903318 79 0.046
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.046
ribonucleotide metabolic process GO:0009259 291 0.045
cellular response to extracellular stimulus GO:0031668 81 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.045
organelle localization GO:0051640 179 0.044
cellular ketone metabolic process GO:0042180 84 0.044
purine containing compound catabolic process GO:0072523 213 0.042
regulation of cellular component biogenesis GO:0044087 181 0.040
response to reactive oxygen species GO:0000302 56 0.040
inclusion body assembly GO:0070841 3 0.040
cellular response to topologically incorrect protein GO:0035967 25 0.040
ameboidal type cell migration GO:0001667 128 0.040
negative regulation of protein depolymerization GO:1901880 21 0.040
response to starvation GO:0042594 65 0.038
fat cell differentiation GO:0045444 160 0.037
purine nucleotide metabolic process GO:0006163 302 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.037
organonitrogen compound catabolic process GO:1901565 264 0.036
protein deacetylation GO:0006476 32 0.036
protein modification by small protein removal GO:0070646 21 0.036
response to oxidative stress GO:0006979 123 0.036
regulation of cellular response to stress GO:0080135 159 0.035
mitotic cell cycle GO:0000278 195 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
tubulin deacetylation GO:0090042 4 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
tissue migration GO:0090130 68 0.034
regulation of cytoskeleton organization GO:0051493 122 0.034
cellular amino acid metabolic process GO:0006520 103 0.034
regulation of microtubule cytoskeleton organization GO:0070507 37 0.034
ribose phosphate metabolic process GO:0019693 291 0.033
aromatic compound catabolic process GO:0019439 286 0.032
regulation of response to oxidative stress GO:1902882 19 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
mitotic cell cycle process GO:1903047 159 0.031
cellular amine metabolic process GO:0044106 44 0.031
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.031
aggresome assembly GO:0070842 2 0.031
posttranscriptional regulation of gene expression GO:0010608 155 0.031
negative regulation of organelle organization GO:0010639 90 0.031
response to growth factor GO:0070848 198 0.031
amine metabolic process GO:0009308 45 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
regulation of cell cycle GO:0051726 281 0.030
chromosome segregation GO:0007059 48 0.030
autophagy GO:0006914 45 0.030
negative regulation of microtubule depolymerization GO:0007026 13 0.030
regulation of protein depolymerization GO:1901879 26 0.030
regulation of microtubule depolymerization GO:0031114 13 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
nuclear division GO:0000280 158 0.028
organelle fission GO:0048285 170 0.028
regulation of protein complex disassembly GO:0043244 28 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.027
cellular protein complex disassembly GO:0043624 36 0.027
response to hydrogen peroxide GO:0042542 32 0.027
positive regulation of cell migration GO:0030335 109 0.027
positive regulation of cell motility GO:2000147 116 0.027
receptor biosynthetic process GO:0032800 3 0.026
histone deacetylation GO:0016575 26 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
regulation of cellular response to oxidative stress GO:1900407 19 0.026
negative regulation of cytoskeleton organization GO:0051494 36 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
regulation of transferase activity GO:0051338 263 0.025
protein deacylation GO:0035601 36 0.025
negative regulation of protein complex disassembly GO:0043242 22 0.025
regulation of cellular catabolic process GO:0031329 242 0.024
regulation of fat cell differentiation GO:0045598 81 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
maintenance of location GO:0051235 89 0.023
nucleotide metabolic process GO:0009117 332 0.023
epithelial cell migration GO:0010631 63 0.023
purine containing compound metabolic process GO:0072521 311 0.023
organelle assembly GO:0070925 177 0.023
dna metabolic process GO:0006259 303 0.023
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
organophosphate catabolic process GO:0046434 232 0.022
peptidyl lysine deacetylation GO:0034983 1 0.021
male gamete generation GO:0048232 285 0.021
cation transport GO:0006812 399 0.021
regulation of membrane potential GO:0042391 192 0.020
rna processing GO:0006396 105 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
misfolded or incompletely synthesized protein catabolic process GO:0006515 4 0.020
nucleoside metabolic process GO:0009116 246 0.019
positive regulation of protein modification process GO:0031401 299 0.019
response to organic cyclic compound GO:0014070 198 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
protein targeting GO:0006605 143 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
cellular homeostasis GO:0019725 240 0.018
Yeast
purine nucleoside metabolic process GO:0042278 241 0.018
nucleoside catabolic process GO:0009164 206 0.018
compound eye development GO:0048749 1 0.018
heterocycle catabolic process GO:0046700 280 0.018
developmental maturation GO:0021700 193 0.018
negative regulation of molecular function GO:0044092 258 0.018
transmembrane transport GO:0055085 412 0.017
muscle cell differentiation GO:0042692 261 0.017
response to organonitrogen compound GO:0010243 246 0.017
regulation of epithelial cell migration GO:0010632 35 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
meiotic nuclear division GO:0007126 115 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
regionalization GO:0003002 337 0.017
membrane organization GO:0061024 245 0.016
regulation of neuron differentiation GO:0045664 281 0.016
rna interference GO:0016246 2 0.016
cell division GO:0051301 120 0.016
immune effector process GO:0002252 321 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
transmission of nerve impulse GO:0019226 76 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
regulation of kinase activity GO:0043549 249 0.016
dephosphorylation GO:0016311 129 0.016
nucleotide catabolic process GO:0009166 217 0.016
regulation of secretion GO:0051046 274 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
maturation of 5 8s rrna GO:0000460 1 0.015
lymphocyte differentiation GO:0030098 242 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
carbohydrate metabolic process GO:0005975 230 0.015
regulation of cell cycle process GO:0010564 160 0.015
action potential GO:0001508 78 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
striated muscle tissue development GO:0014706 293 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
response to topologically incorrect protein GO:0035966 25 0.014
sensory perception GO:0007600 245 0.014
apoptotic signaling pathway GO:0097190 306 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
nitrogen compound transport GO:0071705 271 0.014
regulation of cell activation GO:0050865 289 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
myosin filament organization GO:0031033 3 0.014
regulation of receptor biosynthetic process GO:0010869 2 0.014
germ cell development GO:0007281 185 0.014
multicellular organismal signaling GO:0035637 91 0.013
neuronal action potential GO:0019228 54 0.013
stem cell differentiation GO:0048863 268 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
meiotic cell cycle GO:0051321 122 0.013
positive regulation of transferase activity GO:0051347 167 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
regulation of response to wounding GO:1903034 189 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
regulation of protein kinase activity GO:0045859 232 0.013
multi multicellular organism process GO:0044706 109 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
cytokine production GO:0001816 319 0.013
regulation of peptidase activity GO:0052547 96 0.013
development of primary sexual characteristics GO:0045137 143 0.013
regulation of secretion by cell GO:1903530 249 0.013
skeletal muscle organ development GO:0060538 163 0.013
oxidation reduction process GO:0055114 342 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
positive regulation of kinase activity GO:0033674 155 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
negative regulation of protein modification process GO:0031400 163 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
lipid localization GO:0010876 126 0.012
regulation of oxidative stress induced cell death GO:1903201 14 0.012
forebrain development GO:0030900 302 0.012
muscle tissue development GO:0060537 308 0.012
blood vessel morphogenesis GO:0048514 285 0.012
synapse organization GO:0050808 125 0.012
leukocyte differentiation GO:0002521 342 0.012
response to radiation GO:0009314 165 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
positive regulation of nervous system development GO:0051962 221 0.012
innate immune response GO:0045087 157 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
cellular chemical homeostasis GO:0055082 215 0.012
skeletal system development GO:0001501 356 0.012
gene silencing by rna GO:0031047 19 0.012
multicellular organism growth GO:0035264 161 0.012
gonad development GO:0008406 141 0.012
cation transmembrane transport GO:0098655 266 0.012
positive regulation of cell development GO:0010720 237 0.012
nuclear import GO:0051170 95 0.012
organic anion transport GO:0015711 137 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
anion transport GO:0006820 177 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
cellular response to lipid GO:0071396 145 0.011
methylation GO:0032259 134 0.011
response to light stimulus GO:0009416 135 0.011
camera type eye development GO:0043010 266 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
oocyte construction GO:0007308 2 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
t cell activation GO:0042110 289 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
ossification GO:0001503 216 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of mapk cascade GO:0043408 248 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
locomotory behavior GO:0007626 195 0.011
lateral inhibition GO:0046331 1 0.011
neural tube development GO:0021915 160 0.011
mapk cascade GO:0000165 281 0.011
mitochondrion organization GO:0007005 134 0.010
ribonucleoside monophosphate catabolic process GO:0009158 57 0.010
endocytosis GO:0006897 168 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
positive regulation of cellular response to oxidative stress GO:1900409 6 0.010
angiogenesis GO:0001525 201 0.010
regulation of hormone levels GO:0010817 211 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
regulation of engulfment of apoptotic cell GO:1901074 2 0.010
protein import into nucleus GO:0006606 95 0.010

Plaa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.031
disease of anatomical entity DOID:7 0 0.031
central nervous system disease DOID:331 0 0.015
sensory system disease DOID:0050155 0 0.012