|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.989
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.985
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.984
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.969
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.963
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.955
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.947
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.947
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.946
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.945
|
Human Mouse Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.937
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.929
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.927
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.926
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.925
|
Zebrafish Mouse |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.924
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.923
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.918
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.918
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.915
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.912
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.911
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.909
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.907
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.906
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.896
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.893
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.893
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.889
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.888
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.887
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.881
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.878
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.875
|
Mouse |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.866
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.862
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.860
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.859
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.859
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.848
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.848
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.847
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.843
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.838
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.832
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.832
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.830
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.823
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.821
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.819
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.810
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.807
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.800
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.798
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.787
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.786
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.779
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.772
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.772
|
Fly |
|
|
salivary gland development
|
GO:0007431 |
37 |
0.772
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.763
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.761
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.757
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.757
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.749
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.747
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.746
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.746
|
Mouse |
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.743
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.737
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.736
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.728
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.725
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.724
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.714
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.712
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.699
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.692
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.692
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.692
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.688
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.660
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.660
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.659
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.652
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.651
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.647
|
Rat Fly |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.645
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.645
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.641
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.636
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.630
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.625
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.622
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.620
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.620
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.615
|
Mouse |
|
|
associative learning
|
GO:0008306 |
61 |
0.609
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.604
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.600
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.599
|
Human Zebrafish Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.590
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.577
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.574
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.570
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.563
|
|
|
|
gonadotrophin releasing hormone neuronal migration to the hypothalamus
|
GO:0021828 |
3 |
0.563
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.562
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.560
|
Fly |
|
|
pallium development
|
GO:0021543 |
120 |
0.557
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.550
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.546
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.542
|
Mouse |
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.542
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.536
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.529
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.529
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.528
|
Mouse |
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
3 |
0.517
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.515
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.509
|
Mouse |
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.509
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.503
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.500
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.494
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.493
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.489
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.488
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.484
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.484
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.477
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.471
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.470
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.469
|
Mouse |
|
|
cell growth
|
GO:0016049 |
130 |
0.468
|
Fly |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.468
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.466
|
Mouse Rat |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.466
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.463
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.463
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.453
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.450
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.446
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.440
|
Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.439
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
45 |
0.433
|
Mouse |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.432
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.431
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.431
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.427
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.425
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.425
|
Human Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.425
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.424
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.423
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.423
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.420
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.420
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.416
|
Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.415
|
Mouse |
|
|
telencephalon development
|
GO:0021537 |
186 |
0.414
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.413
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.413
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.413
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.412
|
Zebrafish |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.404
|
Human Mouse Rat |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.403
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.402
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.399
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.396
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.395
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.393
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.391
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.389
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.389
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.387
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.386
|
|
|
|
metanephric mesenchymal cell migration
|
GO:0035789 |
2 |
0.386
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.385
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.381
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.381
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.380
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.380
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.376
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.376
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.375
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.371
|
Fly |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.369
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.368
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.360
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.360
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.359
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.359
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.358
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
31 |
0.358
|
Mouse |
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.356
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.354
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.351
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.347
|
|
|
|
cerebral cortex tangential migration using cell axon interactions
|
GO:0021824 |
3 |
0.346
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.342
|
|
|
|
hypothalamus gonadotrophin releasing hormone neuron development
|
GO:0021888 |
4 |
0.340
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.339
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.331
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.329
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.329
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.328
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.328
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.327
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.325
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.323
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.322
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.317
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.315
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.313
|
Human Rat |
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.307
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.304
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.304
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.304
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.304
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.303
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.302
|
|
|
|
forebrain neuron development
|
GO:0021884 |
30 |
0.302
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.299
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.297
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.297
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.297
|
Mouse |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.294
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.293
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.293
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.291
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.291
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.290
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.288
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.288
|
Mouse |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.286
|
Rat |
|
|
macrophage colony stimulating factor signaling pathway
|
GO:0038145 |
2 |
0.284
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.282
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.280
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.279
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.278
|
|
|
|
response to cocaine
|
GO:0042220 |
14 |
0.277
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.275
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.272
|
Human Mouse |
|
|
neural crest cell migration
|
GO:0001755 |
32 |
0.271
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.270
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.268
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
3 |
0.267
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.267
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.267
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.267
|
|
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
1 |
0.266
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.266
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.266
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.265
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.264
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.263
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.262
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.262
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.260
|
Mouse |
|
|
circadian behavior
|
GO:0048512 |
13 |
0.259
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.259
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.259
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.258
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.258
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.255
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.254
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.254
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.253
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.253
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.252
|
|
|
|
memory
|
GO:0007613 |
58 |
0.247
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.246
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.244
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.244
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.244
|
Mouse |
|
|
learning
|
GO:0007612 |
98 |
0.244
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.243
|
Mouse |
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.242
|
Human Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.240
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.239
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.234
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.234
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.233
|
Fly |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.233
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.233
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.232
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.230
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.230
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.230
|
|
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.227
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.227
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.227
|
Rat |
|
|
muscle system process
|
GO:0003012 |
141 |
0.226
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.225
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.225
|
|
|
|
negative regulation of axon guidance
|
GO:1902668 |
8 |
0.224
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.224
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.223
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.222
|
Human Zebrafish Mouse Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.222
|
Mouse |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.222
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.221
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.219
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.216
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.214
|
Human Mouse Rat |
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.214
|
|
|
|
facioacoustic ganglion development
|
GO:1903375 |
3 |
0.213
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.210
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.210
|
|
|
|
tor signaling
|
GO:0031929 |
21 |
0.210
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.210
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.209
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.208
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.208
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.207
|
Zebrafish |
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.206
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.205
|
Human Zebrafish Mouse Rat |
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.204
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.204
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.203
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.203
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.202
|
Mouse |
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.202
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.201
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.199
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.198
|
Mouse |
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.198
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.197
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.197
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.196
|
|
|
|
erythropoietin mediated signaling pathway
|
GO:0038162 |
1 |
0.196
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.196
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.195
|
|
|
|
smooth muscle cell chemotaxis
|
GO:0071670 |
2 |
0.194
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.194
|
|
|
|
regulation of relaxation of muscle
|
GO:1901077 |
8 |
0.194
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.193
|
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.193
|
Mouse |
|
|
sympathetic neuron projection extension
|
GO:0097490 |
4 |
0.192
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.191
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.191
|
|
|
|
cellular response to stem cell factor stimulus
|
GO:0036216 |
3 |
0.188
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.188
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.188
|
|
|
|
angiogenesis involved in coronary vascular morphogenesis
|
GO:0060978 |
2 |
0.188
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.188
|
Worm Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.186
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.186
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.185
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.185
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.185
|
Human Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.184
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.182
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.181
|
Mouse Rat |
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.181
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.179
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.179
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.179
|
Human Mouse |
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.178
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.178
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.177
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.177
|
Zebrafish |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.176
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.176
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.176
|
Mouse Rat |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.176
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.174
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.172
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.172
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.171
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.168
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.168
|
Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.166
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.165
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.165
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.164
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.163
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.162
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.162
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.162
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.162
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.161
|
|
|
|
trunk neural crest cell migration
|
GO:0036484 |
4 |
0.160
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.160
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.160
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.160
|
Human Mouse Rat |
|
|
defecation
|
GO:0030421 |
1 |
0.159
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.157
|
|
|
|
ventral trunk neural crest cell migration
|
GO:0036486 |
4 |
0.157
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.157
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.157
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.156
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.155
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.155
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.154
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.154
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.154
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.154
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.153
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.153
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.152
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.152
|
Mouse |
|
|
negative regulation of behavior
|
GO:0048521 |
14 |
0.152
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.151
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.151
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.149
|
Mouse |
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.149
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.149
|
Mouse Rat |
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.148
|
Mouse |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.148
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.147
|
|
|
|
smooth muscle cell migration
|
GO:0014909 |
10 |
0.147
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.147
|
|
|
|
sympathetic neuron projection guidance
|
GO:0097491 |
4 |
0.145
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.145
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.144
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.143
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.143
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.143
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.141
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.141
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.141
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.141
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.140
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.140
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.140
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.140
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.139
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.137
|
|
|
|
hypothalamic tangential migration using cell axon interactions
|
GO:0021856 |
3 |
0.137
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.136
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.136
|
Zebrafish |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.135
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.135
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.134
|
Mouse Rat |
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.134
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.134
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.134
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.133
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.133
|
Human Rat |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.131
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.130
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.130
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.130
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.129
|
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
26 |
0.129
|
|
|
|
muscle cell migration
|
GO:0014812 |
19 |
0.128
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.128
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.128
|
Mouse |
|
|
positive regulation of dna biosynthetic process
|
GO:2000573 |
4 |
0.128
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.127
|
|
|
|
regulation of rac gtpase activity
|
GO:0032314 |
13 |
0.127
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.126
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.125
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.125
|
|
|
|
dendritic cell cytokine production
|
GO:0002371 |
3 |
0.124
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.123
|
Human Zebrafish Mouse |
|
|
response to epidermal growth factor
|
GO:0070849 |
4 |
0.122
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.122
|
Mouse Rat |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.122
|
Mouse |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.122
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.121
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.120
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
18 |
0.120
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.120
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.120
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.120
|
|
|
|
positive regulation of glutamate secretion
|
GO:0014049 |
2 |
0.119
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
23 |
0.119
|
Human |
|
|
regulation of vascular smooth muscle contraction
|
GO:0003056 |
1 |
0.118
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.118
|
Rat |
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.118
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.118
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.118
|
Human Mouse |
|
|
female gonad development
|
GO:0008585 |
71 |
0.117
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.115
|
Human |
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.115
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.115
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.114
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.114
|
Human Rat Fly |
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.114
|
Rat |
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
11 |
0.114
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.113
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.113
|
Zebrafish |
|
|
substrate dependent cerebral cortex tangential migration
|
GO:0021825 |
3 |
0.113
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.113
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.112
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
18 |
0.112
|
|
|
|
kit signaling pathway
|
GO:0038109 |
3 |
0.112
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
22 |
0.111
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.111
|
|
|
|
adherens junction maintenance
|
GO:0034334 |
1 |
0.111
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.110
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.109
|
|
|
|
trunk segmentation
|
GO:0035290 |
4 |
0.109
|
|
