|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.960
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.880
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.830
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.808
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.804
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.793
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.782
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.772
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.750
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.744
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.739
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.723
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.718
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.701
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.694
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.689
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.671
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.661
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.657
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.626
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.622
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.610
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.600
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.590
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
15 |
0.586
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.585
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.580
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.575
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.567
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.565
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.564
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.562
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.559
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.548
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.536
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.526
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.525
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.520
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.516
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.482
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.473
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.469
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.459
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.448
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.429
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.404
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.401
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.398
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.385
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.379
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.379
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.375
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.375
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.372
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.365
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.364
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.362
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.362
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.356
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.351
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.346
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.345
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.345
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.343
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.339
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.338
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.336
|
|
|
|
regulation of neutrophil differentiation
|
GO:0045658 |
2 |
0.335
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.330
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.328
|
Human Mouse |
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.326
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.321
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.315
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.315
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.308
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.307
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.306
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.300
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.300
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.288
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.276
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.275
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.274
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.272
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.272
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.267
|
|
|
|
response to platelet derived growth factor
|
GO:0036119 |
6 |
0.265
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.263
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.258
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.256
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
3 |
0.251
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.247
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.242
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.241
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.240
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.240
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.239
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.236
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.235
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.230
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.229
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.229
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.224
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.223
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.221
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.221
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.220
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.220
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.217
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.216
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.214
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.214
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.214
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.214
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.212
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.211
|
Mouse |
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.208
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.206
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.206
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.204
|
Human Mouse |
|
|
learning
|
GO:0007612 |
98 |
0.204
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.200
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.198
|
|
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.197
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.194
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.192
|
|
|
|
filtration diaphragm assembly
|
GO:0036058 |
1 |
0.188
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.185
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.185
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
12 |
0.184
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
19 |
0.184
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.183
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.182
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.182
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.182
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.182
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.181
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.181
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.180
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.179
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.178
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.176
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.176
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.173
|
|
|
|
osteoclast development
|
GO:0036035 |
9 |
0.172
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.172
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.171
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.169
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.168
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.166
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.165
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.164
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.163
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
29 |
0.160
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.159
|
Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.155
|
|
|
|
uterus development
|
GO:0060065 |
16 |
0.152
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.152
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.150
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.149
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.148
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.146
|
Rat |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.146
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.145
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.144
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.144
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
27 |
0.143
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.141
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.141
|
Mouse |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.141
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.139
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.138
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.137
|
|
|
|
negative regulation of mast cell proliferation
|
GO:0070667 |
1 |
0.135
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.134
|
|
|
|
regulation of gamma delta t cell differentiation
|
GO:0045586 |
9 |
0.131
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.129
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.129
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.128
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.125
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.125
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.123
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.123
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.122
|
Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.122
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.122
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.122
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.122
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.120
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.119
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.119
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.118
|
Mouse |
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.117
|
|
|
|
cellular response to platelet derived growth factor stimulus
|
GO:0036120 |
5 |
0.116
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.116
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.116
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.114
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.113
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.113
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.112
|
Fly |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.112
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.111
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.110
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.110
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
4 |
0.110
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.110
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.110
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.110
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.110
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.109
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.108
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.108
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.107
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.107
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.107
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.107
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.106
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.106
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.106
|
Fly |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.106
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.106
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.105
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.103
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.103
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.103
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.103
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.101
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.101
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.101
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.099
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.098
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.097
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.096
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.095
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.095
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.095
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.094
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.093
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.093
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
17 |
0.092
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.092
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.091
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.090
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.090
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.090
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.090
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.089
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.088
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.087
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.087
|
Mouse |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.087
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.086
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.086
|
|
|
|
podosome assembly
|
GO:0071800 |
6 |
0.086
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.083
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.082
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.082
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.082
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.082
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.081
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.081
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.080
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.080
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.080
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.079
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.079
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.079
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.078
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.078
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.078
|
Rat |
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.078
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.077
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.076
|
Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.076
|
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.076
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.076
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.076
|
Mouse |
|
|
parallel actin filament bundle assembly
|
GO:0030046 |
2 |
0.076
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.075
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.074
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.074
|
Mouse |
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.074
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.073
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
27 |
0.073
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.073
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.073
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.072
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.072
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.072
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.072
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.072
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.071
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.070
|
Mouse Fly |
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.069
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.069
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.069
|
Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.068
|
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.067
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.067
|
Fly |
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.067
|
|
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
23 |
0.066
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.066
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.066
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.066
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
4 |
0.066
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.065
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.065
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.065
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.065
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.065
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.065
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.064
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.064
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.063
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.063
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.063
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.063
|
Mouse |
|
|
cognition
|
GO:0050890 |
149 |
0.063
|
Mouse |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.063
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.062
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.062
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.062
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.062
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.061
|
Worm Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.061
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.061
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.061
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.061
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.061
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.061
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.060
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.060
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.060
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.060
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.060
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.060
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.060
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.059
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.059
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.059
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.059
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.059
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.059
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.059
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.059
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.058
|
|
|
|
negative regulation of cell adhesion mediated by integrin
|
GO:0033629 |
2 |
0.058
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.057
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.057
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.057
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
6 |
0.056
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.056
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.056
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
12 |
0.055
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.055
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.055
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.055
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.055
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.054
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.053
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.053
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.053
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.052
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
3 |
0.052
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.052
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.052
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.051
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.051
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
25 |
0.051
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.051
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.051
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
10 |
0.051
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.051
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.051
|
|
|
|
regulation of intracellular estrogen receptor signaling pathway
|
GO:0033146 |
8 |
0.050
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.050
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.050
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.050
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.049
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.048
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.048
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.048
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.048
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.048
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.047
|
|
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
17 |
0.047
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.047
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.047
|
Mouse |
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.047
|
Mouse |
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.046
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.046
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.046
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.046
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.046
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.046
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.046
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.045
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.045
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.045
|
|
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
8 |
0.045
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.045
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.045
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.045
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.045
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.045
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.045
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.044
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.044
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.044
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.044
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.043
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.043
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.043
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.043
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.043
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.042
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.042
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.042
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.042
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
3 |
0.042
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.042
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.042
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.041
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.041
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.041
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.041
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.041
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.041
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.041
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.041
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
8 |
0.040
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.040
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.040
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.040
|
|
|
|
histamine transport
|
GO:0051608 |
2 |
0.040
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.040
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.040
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.040
|
Mouse |
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
6 |
0.040
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.039
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.039
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.039
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.039
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.039
|
|
|
|
nk t cell differentiation
|
GO:0001865 |
8 |
0.039
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.039
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.039
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.039
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.038
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.038
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.038
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.038
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.038
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.038
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.037
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.037
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.037
|
Mouse |
|
|
activation of rac gtpase activity
|
GO:0032863 |
2 |
0.037
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.037
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.037
|
|
|
|
negative regulation of toll like receptor 4 signaling pathway
|
GO:0034144 |
3 |
0.037
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.037
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.036
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.036
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.036
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.036
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.036
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.036
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.036
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.036
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.035
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
23 |
0.035
|
|
|
|
regulation of lipase activity
|
GO:0060191 |
15 |
0.035
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.035
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.035
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.035
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.035
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.035
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.034
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.034
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.034
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.034
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.034
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.034
|
|
|
|
negative regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002924 |
3 |
0.033
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.033
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.033
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.033
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.033
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.033
|
|
