Mus musculus

82 known processes

Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

(Aliases: C920009D07Rik,TAPP1,AA960558)

Plekha1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
estrogen metabolic process GO:0008210 8 0.868
steroid metabolic process GO:0008202 119 0.364
rhythmic process GO:0048511 174 0.355
spermatogenesis GO:0007283 284 0.335
smooth muscle tissue development GO:0048745 22 0.323
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.312
sphingolipid metabolic process GO:0006665 45 0.297
development of primary sexual characteristics GO:0045137 143 0.288
head morphogenesis GO:0060323 34 0.281
purine containing compound metabolic process GO:0072521 311 0.268
female sex differentiation GO:0046660 84 0.259
skeletal system development GO:0001501 356 0.257
kidney development GO:0001822 213 0.254
skeletal system morphogenesis GO:0048705 203 0.246
androgen metabolic process GO:0008209 11 0.240
protein catabolic process GO:0030163 221 0.214
palate development GO:0060021 76 0.201
face development GO:0060324 38 0.201
lateral inhibition GO:0046331 1 0.185
ribonucleoside triphosphate catabolic process GO:0009203 199 0.182
urogenital system development GO:0001655 261 0.177
purine nucleoside triphosphate metabolic process GO:0009144 226 0.168
membrane lipid metabolic process GO:0006643 53 0.162
ovulation cycle GO:0042698 59 0.159
ras protein signal transduction GO:0007265 77 0.135
regulation of hormone levels GO:0010817 211 0.134
ion transmembrane transport GO:0034220 361 0.134
cation transport GO:0006812 399 0.130
glycerophospholipid metabolic process GO:0006650 71 0.127
purine ribonucleotide metabolic process GO:0009150 290 0.126
fibroblast migration GO:0010761 21 0.124
guanosine containing compound metabolic process GO:1901068 144 0.123
guanosine containing compound catabolic process GO:1901069 144 0.122
purine nucleotide metabolic process GO:0006163 302 0.122
hormone metabolic process GO:0042445 86 0.122
purine containing compound catabolic process GO:0072523 213 0.122
nucleotide metabolic process GO:0009117 332 0.121
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.119
ameboidal type cell migration GO:0001667 128 0.114
gonad development GO:0008406 141 0.114
small gtpase mediated signal transduction GO:0007264 97 0.113
purine nucleoside catabolic process GO:0006152 205 0.113
cellular nitrogen compound catabolic process GO:0044270 280 0.111
regulation of transmembrane transport GO:0034762 128 0.109
purine ribonucleoside metabolic process GO:0046128 241 0.108
muscle tissue development GO:0060537 308 0.106
regulation of cellular amino acid metabolic process GO:0006521 5 0.105
carbohydrate derivative catabolic process GO:1901136 231 0.101
ribonucleoside triphosphate metabolic process GO:0009199 220 0.100
ribonucleotide metabolic process GO:0009259 291 0.100
apoptotic signaling pathway GO:0097190 306 0.099
purine nucleotide catabolic process GO:0006195 211 0.099
microtubule based process GO:0007017 236 0.099
nucleoside phosphate catabolic process GO:1901292 222 0.097
transmembrane transport GO:0055085 412 0.095
cellular ion homeostasis GO:0006873 165 0.095
organic cyclic compound catabolic process GO:1901361 295 0.094
glycosyl compound metabolic process GO:1901657 246 0.091
positive regulation of hydrolase activity GO:0051345 148 0.091
nucleoside triphosphate catabolic process GO:0009143 205 0.088
organonitrogen compound catabolic process GO:1901565 264 0.088
cellular lipid metabolic process GO:0044255 323 0.088
glycosylation GO:0070085 62 0.086
nucleotide catabolic process GO:0009166 217 0.086
organophosphate catabolic process GO:0046434 232 0.086
cell fate commitment GO:0045165 210 0.085
renal system development GO:0072001 225 0.085
gtp catabolic process GO:0006184 143 0.083
amine metabolic process GO:0009308 45 0.083
ribonucleoside catabolic process GO:0042454 206 0.081
actin cytoskeleton organization GO:0030036 220 0.081
female gonad development GO:0008585 71 0.080
development of primary female sexual characteristics GO:0046545 73 0.080
cellular homeostasis GO:0019725 240 0.080
nucleoside phosphate metabolic process GO:0006753 338 0.078
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.078
purine ribonucleotide catabolic process GO:0009154 208 0.078
cation homeostasis GO:0055080 212 0.076
ribonucleoside metabolic process GO:0009119 245 0.076
regulation of purine nucleotide metabolic process GO:1900542 169 0.074
response to organic cyclic compound GO:0014070 198 0.074
cellular amine metabolic process GO:0044106 44 0.072
ribonucleotide catabolic process GO:0009261 208 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.069
regulation of nucleoside metabolic process GO:0009118 130 0.069
nucleoside catabolic process GO:0009164 206 0.069
gtp metabolic process GO:0046039 144 0.069
metal ion homeostasis GO:0055065 189 0.067
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.067
purine ribonucleoside catabolic process GO:0046130 205 0.066
glycerolipid metabolic process GO:0046486 122 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.065
regulation of gtp catabolic process GO:0033124 113 0.064
nucleoside metabolic process GO:0009116 246 0.064
cellular response to organic cyclic compound GO:0071407 87 0.063
carbohydrate derivative biosynthetic process GO:1901137 183 0.063
cellular chemical homeostasis GO:0055082 215 0.063
nucleoside triphosphate metabolic process GO:0009141 230 0.062
leukocyte homeostasis GO:0001776 79 0.061
heterocycle catabolic process GO:0046700 280 0.060
protein ubiquitination GO:0016567 171 0.059
cell adhesion GO:0007155 329 0.058
regulation of cellular component biogenesis GO:0044087 181 0.058
purine nucleoside triphosphate catabolic process GO:0009146 203 0.057
response to radiation GO:0009314 165 0.057
purine nucleoside metabolic process GO:0042278 241 0.055
synaptic transmission GO:0007268 329 0.054
organelle assembly GO:0070925 177 0.052
macromolecule catabolic process GO:0009057 281 0.051
ceramide metabolic process GO:0006672 31 0.051
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.050
monocarboxylic acid metabolic process GO:0032787 191 0.050
cellular amino acid metabolic process GO:0006520 103 0.050
homeostasis of number of cells GO:0048872 210 0.048
positive regulation of ras gtpase activity GO:0032320 65 0.048
chemotaxis GO:0006935 247 0.048
regulation of nucleotide catabolic process GO:0030811 122 0.047
protein modification by small protein conjugation GO:0032446 187 0.047
cation transmembrane transport GO:0098655 266 0.047
humoral immune response GO:0006959 57 0.047
b cell activation GO:0042113 161 0.046
regulation of protein localization GO:0032880 231 0.046
positive regulation of protein phosphorylation GO:0001934 242 0.046
aromatic compound catabolic process GO:0019439 286 0.045
ribose phosphate metabolic process GO:0019693 291 0.045
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.044
peptidyl amino acid modification GO:0018193 336 0.044
inorganic cation transmembrane transport GO:0098662 207 0.043
body morphogenesis GO:0010171 45 0.043
regulation of hydrolase activity GO:0051336 246 0.042
calcium ion homeostasis GO:0055074 127 0.042
regulation of system process GO:0044057 200 0.041
regulation of ras gtpase activity GO:0032318 88 0.041
vesicle organization GO:0016050 60 0.041
axon guidance GO:0007411 141 0.041
myeloid cell differentiation GO:0030099 233 0.039
luteinization GO:0001553 8 0.039
regulation of cellular catabolic process GO:0031329 242 0.039
regulation of ion transport GO:0043269 215 0.038
leukocyte differentiation GO:0002521 342 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
inorganic ion transmembrane transport GO:0098660 234 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
macromolecule glycosylation GO:0043413 55 0.037
regulation of lymphocyte activation GO:0051249 240 0.037
modification dependent macromolecule catabolic process GO:0043632 133 0.037
carbohydrate metabolic process GO:0005975 230 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
germ cell development GO:0007281 185 0.036
glycoprotein metabolic process GO:0009100 116 0.035
fatty acid metabolic process GO:0006631 121 0.035
developmental maturation GO:0021700 193 0.035
regulation of nucleotide metabolic process GO:0006140 169 0.035
extrinsic apoptotic signaling pathway GO:0097191 126 0.035
cell substrate adhesion GO:0031589 130 0.035
male gamete generation GO:0048232 285 0.035
regulation of neuron differentiation GO:0045664 281 0.034
cytoplasmic transport GO:0016482 234 0.034
development of primary male sexual characteristics GO:0046546 88 0.034
regulation of ion transmembrane transport GO:0034765 119 0.034
regulation of metal ion transport GO:0010959 106 0.034
regulation of membrane potential GO:0042391 192 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.034
positive regulation of cellular catabolic process GO:0031331 148 0.034
positive regulation of apoptotic process GO:0043065 217 0.034
response to organonitrogen compound GO:0010243 246 0.034
cellular protein complex assembly GO:0043623 116 0.033
vacuole organization GO:0007033 38 0.033
regulation of neuron death GO:1901214 134 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
sphingolipid catabolic process GO:0030149 7 0.033
blood circulation GO:0008015 195 0.033
divalent inorganic cation homeostasis GO:0072507 138 0.032
multicellular organismal signaling GO:0035637 91 0.032
regulation of ras protein signal transduction GO:0046578 114 0.032
response to inorganic substance GO:0010035 96 0.032
Human
regulation of cytoskeleton organization GO:0051493 122 0.031
regulation of purine nucleotide catabolic process GO:0033121 122 0.031
cellular metal ion homeostasis GO:0006875 151 0.031
wound healing GO:0042060 157 0.031
cellular response to biotic stimulus GO:0071216 92 0.030
blood vessel morphogenesis GO:0048514 285 0.030
cellular ketone metabolic process GO:0042180 84 0.030
cytokine production GO:0001816 319 0.030
negative regulation of immune system process GO:0002683 209 0.030
regulation of organelle organization GO:0033043 289 0.030
lipid catabolic process GO:0016042 69 0.029
positive regulation of gtpase activity GO:0043547 85 0.029
positive regulation of nucleotide metabolic process GO:0045981 114 0.029
regulation of anatomical structure size GO:0090066 178 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
negative regulation of molecular function GO:0044092 258 0.029
microtubule cytoskeleton organization GO:0000226 157 0.029
positive regulation of phospholipase c activity GO:0010863 2 0.028
dna metabolic process GO:0006259 303 0.028
defense response to bacterium GO:0042742 119 0.028
nitrogen compound transport GO:0071705 271 0.028
t cell proliferation GO:0042098 120 0.028
sodium ion transport GO:0006814 73 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.028
protein localization to organelle GO:0033365 185 0.028
circulatory system process GO:0003013 197 0.028
response to peptide hormone GO:0043434 127 0.028
anion transport GO:0006820 177 0.027
translation GO:0006412 93 0.027
organic anion transport GO:0015711 137 0.027
locomotory behavior GO:0007626 195 0.027
t cell activation GO:0042110 289 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
muscle system process GO:0003012 141 0.027
divalent metal ion transport GO:0070838 172 0.027
negative regulation of cellular amine metabolic process GO:0033239 1 0.026
cytosolic calcium ion homeostasis GO:0051480 70 0.026
calcium ion transport GO:0006816 159 0.026
regulation of voltage gated calcium channel activity GO:1901385 4 0.026
response to endoplasmic reticulum stress GO:0034976 53 0.026
positive regulation of cell death GO:0010942 224 0.026
maintenance of location GO:0051235 89 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
myeloid cell homeostasis GO:0002262 114 0.026
cellular calcium ion homeostasis GO:0006874 119 0.025
cellular divalent inorganic cation homeostasis GO:0072503 127 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.025
positive regulation of nucleoside metabolic process GO:0045979 91 0.025
protein localization to membrane GO:0072657 108 0.025
forebrain development GO:0030900 302 0.025
regulation of b cell activation GO:0050864 81 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
regulation of neurotransmitter levels GO:0001505 87 0.024
organelle localization GO:0051640 179 0.024
negative regulation of phosphorylation GO:0042326 166 0.024
glycoprotein biosynthetic process GO:0009101 89 0.024
regulation of cell projection organization GO:0031344 206 0.024
actomyosin structure organization GO:0031032 56 0.024
dendritic cell cytokine production GO:0002371 3 0.024
regulation of phospholipase c activity GO:1900274 3 0.024
negative regulation of cell activation GO:0050866 111 0.023
heart contraction GO:0060047 93 0.023
response to peptide GO:1901652 136 0.023
leukocyte mediated immunity GO:0002443 174 0.023
regulation of secretion by cell GO:1903530 249 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
learning or memory GO:0007611 148 0.023
axonogenesis GO:0007409 274 0.023
regulation of actin cytoskeleton organization GO:0032956 84 0.023
leukocyte proliferation GO:0070661 172 0.023
immune effector process GO:0002252 321 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
negative regulation of lymphocyte activation GO:0051250 91 0.023
regulation of cell cycle GO:0051726 281 0.023
response to oxidative stress GO:0006979 123 0.023
Human
rab protein signal transduction GO:0032482 1 0.023
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
positive regulation of gtp catabolic process GO:0033126 85 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
protein polymerization GO:0051258 57 0.022
response to lipopolysaccharide GO:0032496 128 0.022
intracellular protein transport GO:0006886 204 0.022
cellular response to acid chemical GO:0071229 68 0.022
intrinsic apoptotic signaling pathway GO:0097193 132 0.022
actin filament organization GO:0007015 113 0.022
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.022
spermatid development GO:0007286 108 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
stem cell development GO:0048864 219 0.021
cell cell signaling involved in cell fate commitment GO:0045168 35 0.021
protein processing GO:0016485 163 0.021
lipid storage GO:0019915 36 0.021
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.021
rho protein signal transduction GO:0007266 32 0.021
sequestering of calcium ion GO:0051208 18 0.021
positive regulation of nervous system development GO:0051962 221 0.021
multi multicellular organism process GO:0044706 109 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
striated muscle contraction GO:0006941 45 0.020
cell type specific apoptotic process GO:0097285 268 0.020
regulation of cell activation GO:0050865 289 0.020
metanephric mesenchymal cell migration GO:0035789 2 0.020
positive regulation of growth GO:0045927 104 0.020
cellular response to lipid GO:0071396 145 0.020
membrane lipid catabolic process GO:0046466 8 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.020
regulation of cell adhesion GO:0030155 154 0.020
positive regulation of protein modification process GO:0031401 299 0.020
oxidation reduction process GO:0055114 342 0.020
nephron development GO:0072006 109 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.020
metanephric glomerular capillary formation GO:0072277 3 0.020
establishment of organelle localization GO:0051656 122 0.019
angiogenesis GO:0001525 201 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
neuron migration GO:0001764 122 0.019
regulation of actin filament based process GO:0032970 99 0.019
regulation of secretion GO:0051046 274 0.019
regulation of response to wounding GO:1903034 189 0.019
single organism cell adhesion GO:0098602 156 0.019
retrograde transport endosome to golgi GO:0042147 2 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
negative regulation of nervous system development GO:0051961 156 0.019
regulation of establishment of protein localization GO:0070201 181 0.018
synapse organization GO:0050808 125 0.018
nuclear division GO:0000280 158 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
sequestering of metal ion GO:0051238 19 0.018
regulation of t cell activation GO:0050863 170 0.018
organic hydroxy compound transport GO:0015850 93 0.018
regulation of cellular component size GO:0032535 121 0.018
organelle fission GO:0048285 170 0.018
ossification GO:0001503 216 0.018
response to acid chemical GO:0001101 111 0.018
regulation of map kinase activity GO:0043405 120 0.018
cell chemotaxis GO:0060326 81 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
dendrite development GO:0016358 115 0.018
regulation of ion transmembrane transporter activity GO:0032412 54 0.017
adaptive immune response GO:0002250 155 0.017
cellular lipid catabolic process GO:0044242 52 0.017
neuron neuron synaptic transmission GO:0007270 69 0.017
protein glycosylation GO:0006486 55 0.017
sensory perception of sound GO:0007605 97 0.017
rac protein signal transduction GO:0016601 13 0.017
cardiac muscle contraction GO:0060048 32 0.017
action potential GO:0001508 78 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
face morphogenesis GO:0060325 29 0.017
adult behavior GO:0030534 135 0.017
protein targeting GO:0006605 143 0.017
activation of mapk activity GO:0000187 59 0.017
mitotic cell cycle GO:0000278 195 0.017
microtubule polymerization or depolymerization GO:0031109 26 0.017
regulation of leukocyte proliferation GO:0070663 121 0.017
response to insulin GO:0032868 100 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
carbohydrate homeostasis GO:0033500 128 0.016
lymphocyte proliferation GO:0046651 164 0.016
production of molecular mediator of immune response GO:0002440 103 0.016
respiratory system development GO:0060541 190 0.016
spermatid differentiation GO:0048515 115 0.016
regulation of cellular response to stress GO:0080135 159 0.016
regulation of calcium ion transport GO:0051924 69 0.016
mapk cascade GO:0000165 281 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
regulation of rho gtpase activity GO:0032319 58 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
positive regulation of phospholipase activity GO:0010518 3 0.016
endocytosis GO:0006897 168 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
golgi to endosome transport GO:0006895 3 0.016
regulation of muscle system process GO:0090257 80 0.016
striated muscle tissue development GO:0014706 293 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
mitochondrion distribution GO:0048311 4 0.016
pigmentation GO:0043473 71 0.015
establishment of mitochondrion localization GO:0051654 4 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
cellular response to topologically incorrect protein GO:0035967 25 0.015
heart process GO:0003015 94 0.015
oocyte construction GO:0007308 2 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
sensory perception GO:0007600 245 0.015
regulation of protein catabolic process GO:0042176 108 0.015
placenta development GO:0001890 140 0.015
tube formation GO:0035148 140 0.015
positive regulation of kinase activity GO:0033674 155 0.015
positive regulation of potassium ion transport GO:0043268 3 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
divalent inorganic cation transport GO:0072511 178 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
bmp signaling pathway GO:0030509 93 0.015
protein oligomerization GO:0051259 67 0.015
stem cell differentiation GO:0048863 268 0.015
positive regulation of transferase activity GO:0051347 167 0.015
pole plasm assembly GO:0007315 2 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.014
muscle contraction GO:0006936 101 0.014
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.014
circadian regulation of gene expression GO:0032922 48 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
positive regulation of organelle organization GO:0010638 128 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
connective tissue development GO:0061448 179 0.014
regulation of synaptic plasticity GO:0048167 87 0.014
t cell differentiation GO:0030217 174 0.014
endomembrane system organization GO:0010256 147 0.014
positive regulation of dna templated transcription elongation GO:0032786 2 0.014
digestive system development GO:0055123 200 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
detection of stimulus GO:0051606 84 0.014
muscle cell differentiation GO:0042692 261 0.014
phospholipid metabolic process GO:0006644 87 0.014
regulation of peptidyl serine phosphorylation GO:0033135 39 0.014
lymphocyte differentiation GO:0030098 242 0.014
plasma membrane organization GO:0007009 90 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
embryonic placenta development GO:0001892 98 0.013
neuron projection guidance GO:0097485 141 0.013
hemostasis GO:0007599 78 0.013
cardiac muscle cell contraction GO:0086003 7 0.013
regulation of transporter activity GO:0032409 57 0.013
regulation of rho protein signal transduction GO:0035023 71 0.013
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.013
respiratory tube development GO:0030323 167 0.013
positive regulation of cell development GO:0010720 237 0.013
negative regulation of synapse assembly GO:0051964 3 0.013
cell maturation GO:0048469 127 0.013
establishment of vesicle localization GO:0051650 81 0.013
neuron death GO:0070997 154 0.013
embryonic skeletal system development GO:0048706 120 0.013
leukocyte migration GO:0050900 124 0.013
female gamete generation GO:0007292 74 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
learning GO:0007612 98 0.013
regulation of body fluid levels GO:0050878 162 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
gland development GO:0048732 330 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
cell recognition GO:0008037 83 0.013
phosphatidylinositol metabolic process GO:0046488 45 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
cellular protein catabolic process GO:0044257 155 0.013
lipid transport GO:0006869 98 0.013
fat cell differentiation GO:0045444 160 0.013
sensory organ morphogenesis GO:0090596 242 0.013
phenol containing compound metabolic process GO:0018958 60 0.013
cytokinetic process GO:0032506 2 0.013
regulation of cell shape GO:0008360 39 0.013
monosaccharide transport GO:0015749 58 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
neurotransmitter transport GO:0006836 76 0.012
male sex differentiation GO:0046661 109 0.012
regulation of ion homeostasis GO:2000021 64 0.012
golgi vesicle transport GO:0048193 30 0.012
cell division GO:0051301 120 0.012
regulation of blood vessel remodeling GO:0060312 3 0.012
oocyte axis specification GO:0007309 2 0.012
inositol lipid mediated signaling GO:0048017 41 0.012
Human
developmental growth involved in morphogenesis GO:0060560 138 0.012
regulation of intracellular transport GO:0032386 159 0.012
metanephric glomerular mesangium development GO:0072223 3 0.012
regulation of microtubule based process GO:0032886 52 0.012
wnt signaling pathway GO:0016055 188 0.012
cell growth GO:0016049 130 0.012
axon ensheathment GO:0008366 76 0.012
regulation of t cell proliferation GO:0042129 92 0.012
glial cell differentiation GO:0010001 131 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
b cell proliferation GO:0042100 53 0.012
epithelial cell development GO:0002064 159 0.012
epithelial cell proliferation GO:0050673 174 0.012
macromolecular complex disassembly GO:0032984 43 0.012
regulation of cell motility GO:2000145 236 0.012
neuronal action potential GO:0019228 54 0.012
positive regulation of ion transport GO:0043270 65 0.012
meiotic nuclear division GO:0007126 115 0.012
epithelial tube formation GO:0072175 130 0.012
glucose transport GO:0015758 56 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
protein maturation GO:0051604 176 0.012
endocrine system development GO:0035270 98 0.012
cellular response to thyroid hormone stimulus GO:0097067 1 0.012
regulation of adaptive immune response GO:0002819 90 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.011
calcium ion transmembrane transport GO:0070588 85 0.011
negative regulation of neuron death GO:1901215 98 0.011
mitotic cell cycle process GO:1903047 159 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
gliogenesis GO:0042063 141 0.011
protein localization to plasma membrane GO:0072659 57 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of blood circulation GO:1903522 93 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
Human
response to oxygen levels GO:0070482 62 0.011
regulation of protein maturation GO:1903317 96 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
regulation of protein kinase activity GO:0045859 232 0.011
compound eye development GO:0048749 1 0.011
ear development GO:0043583 200 0.011
epithelial cell morphogenesis GO:0003382 41 0.011

Plekha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.052
neuropathy DOID:870 0 0.027
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
neuromuscular disease DOID:440 0 0.019