Mus musculus

0 known processes

Plekhg2

pleckstrin homology domain containing, family G (with RhoGef domain) member 2

(Aliases: Clg,AI194308,Cslg)

Plekhg2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleoside phosphate metabolic process GO:0006753 338 0.380
purine nucleoside metabolic process GO:0042278 241 0.379
cell adhesion GO:0007155 329 0.347
actin cytoskeleton organization GO:0030036 220 0.334
purine ribonucleotide metabolic process GO:0009150 290 0.329
small gtpase mediated signal transduction GO:0007264 97 0.328
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.310
regulation of nucleotide metabolic process GO:0006140 169 0.302
purine nucleoside catabolic process GO:0006152 205 0.294
ribonucleoside metabolic process GO:0009119 245 0.286
glycosyl compound catabolic process GO:1901658 206 0.286
nucleoside metabolic process GO:0009116 246 0.284
nucleotide metabolic process GO:0009117 332 0.283
regulation of gtp catabolic process GO:0033124 113 0.277
ribonucleotide catabolic process GO:0009261 208 0.276
regulation of nucleoside metabolic process GO:0009118 130 0.272
actin filament organization GO:0007015 113 0.270
nucleobase containing small molecule metabolic process GO:0055086 352 0.252
purine ribonucleoside metabolic process GO:0046128 241 0.245
nucleotide catabolic process GO:0009166 217 0.235
ribonucleotide metabolic process GO:0009259 291 0.221
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.210
nucleoside triphosphate metabolic process GO:0009141 230 0.209
regulation of nucleotide catabolic process GO:0030811 122 0.209
gtp metabolic process GO:0046039 144 0.209
regulation of hydrolase activity GO:0051336 246 0.205
purine containing compound catabolic process GO:0072523 213 0.197
regulation of cellular catabolic process GO:0031329 242 0.197
purine nucleoside triphosphate catabolic process GO:0009146 203 0.189
cellular amino acid metabolic process GO:0006520 103 0.187
cell matrix adhesion GO:0007160 68 0.184
nucleoside triphosphate catabolic process GO:0009143 205 0.183
ribonucleoside triphosphate metabolic process GO:0009199 220 0.178
ribonucleoside triphosphate catabolic process GO:0009203 199 0.178
i kappab kinase nf kappab signaling GO:0007249 85 0.177
purine containing compound metabolic process GO:0072521 311 0.175
glycosyl compound metabolic process GO:1901657 246 0.172
mapk cascade GO:0000165 281 0.171
ribonucleoside catabolic process GO:0042454 206 0.171
response to growth factor GO:0070848 198 0.170
carbohydrate derivative catabolic process GO:1901136 231 0.169
ribose phosphate metabolic process GO:0019693 291 0.164
gtp catabolic process GO:0006184 143 0.160
purine ribonucleoside catabolic process GO:0046130 205 0.160
amine metabolic process GO:0009308 45 0.160
purine nucleotide catabolic process GO:0006195 211 0.159
ras protein signal transduction GO:0007265 77 0.152
regulation of purine nucleotide catabolic process GO:0033121 122 0.150
regulation of cellular ketone metabolic process GO:0010565 66 0.149
leukocyte differentiation GO:0002521 342 0.148
regulation of ras protein signal transduction GO:0046578 114 0.147
regulation of cell motility GO:2000145 236 0.145
regulation of purine nucleotide metabolic process GO:1900542 169 0.144
regulation of cellular amino acid metabolic process GO:0006521 5 0.140
organic cyclic compound catabolic process GO:1901361 295 0.133
cellular nitrogen compound catabolic process GO:0044270 280 0.131
regulation of cell migration GO:0030334 219 0.126
regulation of mapk cascade GO:0043408 248 0.125
cellular response to growth factor stimulus GO:0071363 197 0.125
cellular ketone metabolic process GO:0042180 84 0.120
guanosine containing compound metabolic process GO:1901068 144 0.120
epithelial cell development GO:0002064 159 0.107
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.106
guanosine containing compound catabolic process GO:1901069 144 0.106
organonitrogen compound catabolic process GO:1901565 264 0.106
regulation of ras gtpase activity GO:0032318 88 0.103
nucleoside phosphate catabolic process GO:1901292 222 0.099
regulation of apoptotic signaling pathway GO:2001233 197 0.098
mitotic cell cycle GO:0000278 195 0.098
cellular amine metabolic process GO:0044106 44 0.098
regulation of cellular amine metabolic process GO:0033238 20 0.098
nucleoside catabolic process GO:0009164 206 0.096
heterocycle catabolic process GO:0046700 280 0.095
response to transforming growth factor beta GO:0071559 88 0.095
defense response to other organism GO:0098542 197 0.093
synaptic transmission GO:0007268 329 0.092
wnt signaling pathway GO:0016055 188 0.091
aromatic compound catabolic process GO:0019439 286 0.090
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.090
regulation of rho protein signal transduction GO:0035023 71 0.090
axonogenesis GO:0007409 274 0.088
chemotaxis GO:0006935 247 0.088
regulation of organelle organization GO:0033043 289 0.087
positive regulation of cell development GO:0010720 237 0.086
purine nucleotide metabolic process GO:0006163 302 0.084
purine nucleoside triphosphate metabolic process GO:0009144 226 0.083
organophosphate catabolic process GO:0046434 232 0.083
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.083
regulation of cell adhesion GO:0030155 154 0.082
ovulation GO:0030728 15 0.080
regulation of wnt signaling pathway GO:0030111 123 0.077
asymmetric neuroblast division GO:0055059 1 0.077
stem cell differentiation GO:0048863 268 0.075
cell cell adhesion GO:0098609 41 0.075
positive regulation of protein phosphorylation GO:0001934 242 0.073
regulation of cellular response to stress GO:0080135 159 0.072
negative regulation of wnt signaling pathway GO:0030178 73 0.072
positive regulation of nucleoside metabolic process GO:0045979 91 0.071
mesenchymal cell development GO:0014031 93 0.067
negative regulation of molecular function GO:0044092 258 0.067
regulation of protein serine threonine kinase activity GO:0071900 157 0.066
response to organonitrogen compound GO:0010243 246 0.065
negative regulation of protein modification process GO:0031400 163 0.065
regulation of neuron differentiation GO:0045664 281 0.064
muscle cell differentiation GO:0042692 261 0.064
rho protein signal transduction GO:0007266 32 0.064
negative regulation of protein phosphorylation GO:0001933 126 0.064
ossification GO:0001503 216 0.063
epithelial to mesenchymal transition GO:0001837 47 0.062
glycerolipid biosynthetic process GO:0045017 50 0.062
positive regulation of cellular amine metabolic process GO:0033240 5 0.061
cell substrate adhesion GO:0031589 130 0.061
regulation of leukocyte differentiation GO:1902105 159 0.060
single organismal cell cell adhesion GO:0016337 131 0.058
canonical wnt signaling pathway GO:0060070 130 0.057
macromolecule catabolic process GO:0009057 281 0.055
regulation of protein kinase activity GO:0045859 232 0.055
negative regulation of nervous system development GO:0051961 156 0.054
neuron projection guidance GO:0097485 141 0.054
negative regulation of protein metabolic process GO:0051248 282 0.053
positive regulation of nervous system development GO:0051962 221 0.053
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.053
positive regulation of protein modification process GO:0031401 299 0.052
purine ribonucleotide catabolic process GO:0009154 208 0.052
regulation of osteoblast differentiation GO:0045667 67 0.051
regulation of protein localization GO:0032880 231 0.051
phospholipid metabolic process GO:0006644 87 0.051
negative regulation of cellular component organization GO:0051129 194 0.050
cell junction organization GO:0034330 77 0.050
lamellipodium organization GO:0097581 29 0.050
cell cell junction organization GO:0045216 72 0.050
muscle tissue development GO:0060537 308 0.049
positive regulation of apoptotic process GO:0043065 217 0.049
regulation of cell activation GO:0050865 289 0.048
regulation of transferase activity GO:0051338 263 0.048
glycerophospholipid biosynthetic process GO:0046474 32 0.048
focal adhesion assembly GO:0048041 19 0.048
microtubule cytoskeleton organization GO:0000226 157 0.048
negative regulation of phosphorylation GO:0042326 166 0.048
asymmetric stem cell division GO:0098722 3 0.047
angiogenesis GO:0001525 201 0.046
regulation of kinase activity GO:0043549 249 0.046
forebrain development GO:0030900 302 0.045
mesenchymal cell differentiation GO:0048762 107 0.045
defecation GO:0030421 1 0.044
striated muscle cell development GO:0055002 125 0.044
stem cell development GO:0048864 219 0.043
endocytosis GO:0006897 168 0.042
morphogenesis of embryonic epithelium GO:0016331 159 0.042
embryonic organ morphogenesis GO:0048562 276 0.042
digestive tract development GO:0048565 190 0.042
negative regulation of phosphate metabolic process GO:0045936 184 0.041
cell substrate adherens junction assembly GO:0007045 19 0.041
positive regulation of gtp catabolic process GO:0033126 85 0.041
negative regulation of cell proliferation GO:0008285 296 0.041
positive regulation of transferase activity GO:0051347 167 0.040
cellular lipid metabolic process GO:0044255 323 0.040
intracellular protein transport GO:0006886 204 0.040
cellular response to organonitrogen compound GO:0071417 145 0.040
muscle cell development GO:0055001 133 0.039
positive regulation of cell death GO:0010942 224 0.039
substrate dependent cell migration GO:0006929 18 0.039
regulation of establishment of protein localization GO:0070201 181 0.039
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.038
wound healing spreading of cells GO:0044319 8 0.038
lipid biosynthetic process GO:0008610 179 0.038
defense response to bacterium GO:0042742 119 0.038
protein catabolic process GO:0030163 221 0.038
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
lung development GO:0030324 164 0.037
renal system development GO:0072001 225 0.036
regulation of protein transport GO:0051223 163 0.036
oxidation reduction process GO:0055114 342 0.036
apoptotic signaling pathway GO:0097190 306 0.036
negative regulation of phagocytosis GO:0050765 4 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
hemostasis GO:0007599 78 0.036
glycerophospholipid metabolic process GO:0006650 71 0.036
mitotic cell cycle process GO:1903047 159 0.036
transmembrane transport GO:0055085 412 0.036
positive regulation of apoptotic signaling pathway GO:2001235 95 0.036
stem cell proliferation GO:0072089 117 0.036
peptidyl amino acid modification GO:0018193 336 0.036
g protein coupled receptor signaling pathway GO:0007186 243 0.036
oocyte anterior posterior axis specification GO:0007314 2 0.036
negative regulation of cellular amine metabolic process GO:0033239 1 0.035
nuclear transport GO:0051169 139 0.035
extracellular structure organization GO:0043062 148 0.035
skin development GO:0043588 220 0.035
positive regulation of mapk cascade GO:0043410 170 0.035
regulation of cytoskeleton organization GO:0051493 122 0.035
maternal determination of anterior posterior axis embryo GO:0008358 2 0.035
single organism cell adhesion GO:0098602 156 0.035
cytoplasmic transport GO:0016482 234 0.035
urogenital system development GO:0001655 261 0.034
axon guidance GO:0007411 141 0.034
negative regulation of osteoblast differentiation GO:0045668 30 0.034
neural precursor cell proliferation GO:0061351 121 0.034
positive regulation of cellular catabolic process GO:0031331 148 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.033
t cell activation GO:0042110 289 0.033
striated muscle tissue development GO:0014706 293 0.033
myeloid leukocyte differentiation GO:0002573 119 0.033
regulation of map kinase activity GO:0043405 120 0.032
muscle fiber development GO:0048747 76 0.032
developmental growth involved in morphogenesis GO:0060560 138 0.032
regulation of ossification GO:0030278 112 0.032
epithelial cell morphogenesis GO:0003382 41 0.032
positive regulation of hydrolase activity GO:0051345 148 0.031
synapse organization GO:0050808 125 0.031
skeletal muscle organ development GO:0060538 163 0.031
epithelial cell migration GO:0010631 63 0.031
response to inorganic substance GO:0010035 96 0.031
compound eye development GO:0048749 1 0.031
regulation of lymphocyte activation GO:0051249 240 0.030
positive regulation of organelle organization GO:0010638 128 0.030
extracellular matrix organization GO:0030198 147 0.030
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.030
microtubule based process GO:0007017 236 0.030
response to organic cyclic compound GO:0014070 198 0.030
developmental maturation GO:0021700 193 0.029
respiratory system development GO:0060541 190 0.029
epithelial tube morphogenesis GO:0060562 303 0.029
wound healing GO:0042060 157 0.028
organelle assembly GO:0070925 177 0.028
positive regulation of innate immune response GO:0045089 80 0.028
gliogenesis GO:0042063 141 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
digestive system development GO:0055123 200 0.028
rac protein signal transduction GO:0016601 13 0.028
neuron migration GO:0001764 122 0.028
ameboidal type cell migration GO:0001667 128 0.028
regulation of canonical wnt signaling pathway GO:0060828 82 0.027
ion transmembrane transport GO:0034220 361 0.027
regulation of vesicle mediated transport GO:0060627 139 0.027
phospholipid biosynthetic process GO:0008654 36 0.027
regulation of anatomical structure size GO:0090066 178 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
dephosphorylation GO:0016311 129 0.026
cation transport GO:0006812 399 0.026
negative regulation of immune system process GO:0002683 209 0.026
placenta development GO:0001890 140 0.026
morphogenesis of a branching epithelium GO:0061138 193 0.026
fat cell differentiation GO:0045444 160 0.026
branching morphogenesis of an epithelial tube GO:0048754 159 0.026
glycerolipid metabolic process GO:0046486 122 0.026
positive regulation of protein transport GO:0051222 93 0.026
positive regulation of ras gtpase activity GO:0032320 65 0.026
organelle fission GO:0048285 170 0.026
integrin mediated signaling pathway GO:0007229 27 0.026
cytokine production GO:0001816 319 0.025
mitotic cytokinesis GO:0000281 4 0.025
regulation of neuron projection development GO:0010975 169 0.025
oocyte axis specification GO:0007309 2 0.025
organophosphate biosynthetic process GO:0090407 122 0.025
positive regulation of map kinase activity GO:0043406 84 0.025
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.025
regulation of rho gtpase activity GO:0032319 58 0.024
protein targeting GO:0006605 143 0.024
maintenance of apical basal cell polarity GO:0035090 3 0.024
muscle system process GO:0003012 141 0.024
blood vessel morphogenesis GO:0048514 285 0.024
actomyosin structure organization GO:0031032 56 0.024
negative regulation of cell motility GO:2000146 61 0.024
membrane organization GO:0061024 245 0.024
development of primary sexual characteristics GO:0045137 143 0.024
positive regulation of neuron projection development GO:0010976 79 0.024
regulation of cytokine production GO:0001817 266 0.023
cell fate commitment GO:0045165 210 0.023
positive regulation of cellular component biogenesis GO:0044089 94 0.023
olfactory learning GO:0008355 2 0.023
t cell differentiation GO:0030217 174 0.023
regulation of epithelial cell migration GO:0010632 35 0.023
regulation of secretion GO:0051046 274 0.023
erk1 and erk2 cascade GO:0070371 77 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
gastrulation GO:0007369 116 0.022
chromatin modification GO:0016568 187 0.022
adherens junction assembly GO:0034333 22 0.022
respiratory tube development GO:0030323 167 0.022
muscle contraction GO:0006936 101 0.022
regulation of vasculature development GO:1901342 88 0.022
response to hypoxia GO:0001666 58 0.022
regulation of membrane potential GO:0042391 192 0.022
regulation of fat cell differentiation GO:0045598 81 0.022
regulation of histone modification GO:0031056 56 0.022
cellular response to lipid GO:0071396 145 0.022
response to alcohol GO:0097305 48 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.021
positive regulation of gtpase activity GO:0043547 85 0.021
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.021
response to oxygen levels GO:0070482 62 0.021
mesenchyme development GO:0060485 152 0.021
regulation of cell projection organization GO:0031344 206 0.021
positive regulation of cytoplasmic transport GO:1903651 40 0.021
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.021
actin cytoskeleton reorganization GO:0031532 21 0.021
learning or memory GO:0007611 148 0.021
homotypic cell cell adhesion GO:0034109 28 0.021
skeletal system development GO:0001501 356 0.021
t cell differentiation in thymus GO:0033077 77 0.021
telencephalon development GO:0021537 186 0.021
regulation of stem cell differentiation GO:2000736 50 0.020
regulation of defense response GO:0031347 233 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
adherens junction organization GO:0034332 28 0.020
peptidyl tyrosine phosphorylation GO:0018108 143 0.020
negative regulation of cell migration GO:0030336 59 0.020
gene silencing by mirna GO:0035195 10 0.020
peptidyl tyrosine modification GO:0018212 145 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
retina development in camera type eye GO:0060041 119 0.020
regulation of protein complex assembly GO:0043254 83 0.020
positive regulation of nucleotide catabolic process GO:0030813 88 0.020
regulation of innate immune response GO:0045088 91 0.020
regulation of cellular component size GO:0032535 121 0.020
regulation of chromatin modification GO:1903308 57 0.019
cellular response to dna damage stimulus GO:0006974 207 0.019
cellular response to organic cyclic compound GO:0071407 87 0.019
regulation of t cell activation GO:0050863 170 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
regulation of lymphocyte differentiation GO:0045619 107 0.019
norepinephrine transport GO:0015874 2 0.019
endomembrane system organization GO:0010256 147 0.019
gonad development GO:0008406 141 0.019
activation of immune response GO:0002253 138 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
regulation of muscle tissue development GO:1901861 97 0.019
cellular response to acid chemical GO:0071229 68 0.018
multicellular organismal signaling GO:0035637 91 0.018
cilium morphogenesis GO:0060271 102 0.018
actin filament polymerization GO:0030041 44 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
cardiac muscle tissue development GO:0048738 130 0.018
substrate dependent cell migration cell extension GO:0006930 4 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.018
regulation of endocytosis GO:0030100 69 0.018
chromatin organization GO:0006325 206 0.018
cellular homeostasis GO:0019725 240 0.018
maintenance of location GO:0051235 89 0.018
regulation of endodermal cell differentiation GO:1903224 2 0.018
regulation of protein import into nucleus GO:0042306 52 0.017
morphogenesis of an epithelial sheet GO:0002011 27 0.017
adult behavior GO:0030534 135 0.017
rab protein signal transduction GO:0032482 1 0.017
myotube differentiation GO:0014902 105 0.017
cardiac cell development GO:0055006 41 0.017
neuron death GO:0070997 154 0.017
histone modification GO:0016570 159 0.017
skeletal system morphogenesis GO:0048705 203 0.017
tissue migration GO:0090130 68 0.017
small molecule biosynthetic process GO:0044283 132 0.017
homeostasis of number of cells GO:0048872 210 0.017
glial cell differentiation GO:0010001 131 0.017
carbohydrate metabolic process GO:0005975 230 0.017
neuron projection extension GO:1990138 64 0.017
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 9 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.017
stem cell maintenance GO:0019827 130 0.017
osteoblast development GO:0002076 17 0.017
lymphocyte proliferation GO:0046651 164 0.017
positive regulation of immature t cell proliferation GO:0033091 4 0.017
lymphocyte differentiation GO:0030098 242 0.017
cellular protein complex assembly GO:0043623 116 0.017
nitrogen compound transport GO:0071705 271 0.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.017
response to oxidative stress GO:0006979 123 0.017
sensory organ morphogenesis GO:0090596 242 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
response to radiation GO:0009314 165 0.017
alpha beta t cell activation GO:0046631 91 0.017
response to acid chemical GO:0001101 111 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
mesodermal cell migration GO:0008078 4 0.017
nuclear division GO:0000280 158 0.016
negative regulation of ossification GO:0030279 49 0.016
interleukin 8 production GO:0032637 4 0.016
blood coagulation GO:0007596 76 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
organelle localization GO:0051640 179 0.016
plasma membrane organization GO:0007009 90 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
segmentation GO:0035282 93 0.016
biomineral tissue development GO:0031214 64 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
regulation of secretion by cell GO:1903530 249 0.016
positive regulation of cell activation GO:0050867 158 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
myosin filament assembly GO:0031034 2 0.016
embryonic placenta development GO:0001892 98 0.016
regulation of stem cell proliferation GO:0072091 78 0.016
gene silencing by rna GO:0031047 19 0.016
pharynx development GO:0060465 1 0.016
wound healing spreading of epidermal cells GO:0035313 5 0.016
dorsal ventral axon guidance GO:0033563 3 0.016
cell substrate junction assembly GO:0007044 24 0.015
positive regulation of rho gtpase activity GO:0032321 41 0.015
early endosome to late endosome transport GO:0045022 2 0.015
negative regulation of transferase activity GO:0051348 85 0.015
cardiac muscle cell differentiation GO:0055007 69 0.015
b cell activation GO:0042113 161 0.015
regulation of chromosome organization GO:0033044 83 0.015
oocyte construction GO:0007308 2 0.015
positive regulation of growth GO:0045927 104 0.015
sensory perception GO:0007600 245 0.015
hindbrain development GO:0030902 128 0.015
regulation of cellular response to growth factor stimulus GO:0090287 82 0.015
protein import into nucleus GO:0006606 95 0.015
immune response activating signal transduction GO:0002757 116 0.015
multicellular organism growth GO:0035264 161 0.015
lateral inhibition GO:0046331 1 0.015
trabecula morphogenesis GO:0061383 40 0.015
regulation of myotube differentiation GO:0010830 62 0.015
stress activated mapk cascade GO:0051403 80 0.015
negative regulation of cell development GO:0010721 169 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
positive regulation of interleukin 8 production GO:0032757 2 0.015
male gamete generation GO:0048232 285 0.014
regulation of interleukin 2 production GO:0032663 28 0.014
regulation of intracellular transport GO:0032386 159 0.014
regulation of embryonic development GO:0045995 71 0.014
nuclear import GO:0051170 95 0.014
regulation of myeloid leukocyte differentiation GO:0002761 58 0.014
action potential GO:0001508 78 0.014
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.014
protein import GO:0017038 101 0.014
cell cycle g1 s phase transition GO:0044843 57 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
ear development GO:0043583 200 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
protein localization to nucleus GO:0034504 121 0.014
female gamete generation GO:0007292 74 0.014
regulation of vitamin metabolic process GO:0030656 3 0.014
protein secretion GO:0009306 111 0.014
innate immune response GO:0045087 157 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
cell aging GO:0007569 35 0.014
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.014
phagocytosis GO:0006909 66 0.014
negative regulation of organelle organization GO:0010639 90 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
dna metabolic process GO:0006259 303 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
establishment of organelle localization GO:0051656 122 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
protein localization to membrane GO:0072657 108 0.014
regulation of cell shape GO:0008360 39 0.014
digestive tract morphogenesis GO:0048546 147 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
regulation of nucleocytoplasmic transport GO:0046822 73 0.014
cardiac chamber morphogenesis GO:0003206 93 0.014
gland development GO:0048732 330 0.014
peptidyl serine modification GO:0018209 83 0.014
regulation of neuron migration GO:2001222 22 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
single organism nuclear import GO:1902593 95 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.014
negative regulation of lymphocyte activation GO:0051250 91 0.014
defense response to virus GO:0051607 68 0.013
cell junction assembly GO:0034329 52 0.013
positive regulation of creb transcription factor activity GO:0032793 4 0.013
leukocyte proliferation GO:0070661 172 0.013
spermatogenesis GO:0007283 284 0.013
rhythmic process GO:0048511 174 0.013
neural tube development GO:0021915 160 0.013
regulation of transcription factor import into nucleus GO:0042990 24 0.013
aortic valve morphogenesis GO:0003180 4 0.013
cation transmembrane transport GO:0098655 266 0.013
apical constriction GO:0003383 4 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of actin filament based process GO:0032970 99 0.013
mitotic nuclear division GO:0007067 48 0.013
inflammatory response GO:0006954 244 0.013
protein localization to organelle GO:0033365 185 0.013
positive regulation of cytokine production GO:0001819 174 0.013
positive regulation of gene silencing by mirna GO:2000637 1 0.013
cognition GO:0050890 149 0.013

Plekhg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
physical disorder DOID:0080015 0 0.023
congenital nervous system abnormality DOID:2490 0 0.023
x linked disease DOID:0050735 0 0.021
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
musculoskeletal system disease DOID:17 0 0.015