|
|
spindle assembly involved in mitosis
|
GO:0090307 |
4 |
0.979
|
|
|
|
microtubule cytoskeleton organization involved in mitosis
|
GO:1902850 |
4 |
0.976
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.969
|
Human Yeast Worm Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.925
|
Yeast |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.913
|
Yeast Fly |
|
|
cleavage furrow formation
|
GO:0036089 |
2 |
0.912
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.907
|
Human Yeast Mouse Worm |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.898
|
Human Mouse Worm Fly |
|
|
spindle assembly
|
GO:0051225 |
13 |
0.897
|
Yeast Fly |
|
|
cytokinesis
|
GO:0000910 |
17 |
0.874
|
Human Rat Worm Fly |
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
15 |
0.864
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.843
|
Human Yeast Worm |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.840
|
Human Zebrafish Mouse Worm Fly |
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
4 |
0.837
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.830
|
Human Yeast Worm Fly |
|
|
microtubule organizing center organization
|
GO:0031023 |
28 |
0.816
|
Human Yeast Worm Fly |
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
14 |
0.816
|
Human |
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.813
|
Human |
|
|
cell division
|
GO:0051301 |
120 |
0.805
|
Human Rat Worm Fly |
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.782
|
Human Worm |
|
|
microtubule depolymerization
|
GO:0007019 |
15 |
0.766
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.745
|
Human Yeast Mouse Worm |
|
|
nuclear division
|
GO:0000280 |
158 |
0.734
|
Human Yeast Rat Worm Fly |
|
|
centrosome cycle
|
GO:0007098 |
23 |
0.734
|
Worm |
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.733
|
Yeast Rat Worm Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.729
|
Human Mouse |
|
|
organelle fission
|
GO:0048285 |
170 |
0.707
|
Human Yeast Rat Worm Fly |
|
|
centrosome duplication
|
GO:0051298 |
16 |
0.660
|
|
|
|
metaphase plate congression
|
GO:0051310 |
2 |
0.628
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.627
|
Yeast Rat Worm Fly |
|
|
organelle localization
|
GO:0051640 |
179 |
0.620
|
Fly |
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.594
|
Human |
|
|
regulation of microtubule depolymerization
|
GO:0031114 |
13 |
0.590
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.579
|
Yeast |
|
|
regulation of spindle organization
|
GO:0090224 |
2 |
0.574
|
|
|
|
positive regulation of mitotic metaphase anaphase transition
|
GO:0045842 |
2 |
0.572
|
Human |
|
|
regulation of mitotic spindle organization
|
GO:0060236 |
2 |
0.524
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.520
|
Yeast |
|
|
cytokinetic process
|
GO:0032506 |
2 |
0.506
|
Fly |
|
|
spindle midzone assembly
|
GO:0051255 |
1 |
0.497
|
Fly |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.490
|
Human |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.479
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.466
|
Human Worm Fly |
|
|
sister chromatid segregation
|
GO:0000819 |
20 |
0.452
|
Human |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.443
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.440
|
Human Yeast |
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.436
|
|
|
|
meiotic cytokinesis
|
GO:0033206 |
5 |
0.429
|
Rat Worm Fly |
|
|
mitotic chromosome condensation
|
GO:0007076 |
1 |
0.424
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.395
|
Yeast Rat Worm Fly |
|
|
astral microtubule organization
|
GO:0030953 |
3 |
0.392
|
Fly |
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.387
|
Human |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.378
|
Human Yeast Worm |
|
|
histone serine phosphorylation
|
GO:0035404 |
5 |
0.376
|
|
|
|
centrosome separation
|
GO:0051299 |
4 |
0.375
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.375
|
|
|
|
negative regulation of microtubule depolymerization
|
GO:0007026 |
13 |
0.361
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.359
|
Human |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.358
|
Human Yeast |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.357
|
Human Mouse |
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.352
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
4 |
0.338
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.336
|
|
|
|
dna endoreduplication
|
GO:0042023 |
4 |
0.333
|
|
|
|
mitotic centrosome separation
|
GO:0007100 |
4 |
0.333
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.330
|
Human Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.329
|
Human Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.327
|
Human |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.316
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.316
|
Human |
|
|
response to cell cycle checkpoint signaling
|
GO:0072396 |
1 |
0.310
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.308
|
Human Mouse |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.304
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.298
|
Mouse |
|
|
female meiosis chromosome segregation
|
GO:0016321 |
1 |
0.294
|
|
|
|
centrosome organization
|
GO:0051297 |
26 |
0.288
|
Human Worm Fly |
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.282
|
Fly |
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.278
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.274
|
Human |
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
1 |
0.272
|
|
|
|
chromosome movement towards spindle pole
|
GO:0051305 |
3 |
0.272
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.266
|
|
|
|
spindle localization
|
GO:0051653 |
22 |
0.264
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.264
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.262
|
|
|
|
spindle organization
|
GO:0007051 |
28 |
0.256
|
Yeast Worm Fly |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.256
|
Human |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.255
|
Human Mouse |
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.253
|
Human Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.251
|
Human |
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.251
|
|
|
|
histone phosphorylation
|
GO:0016572 |
9 |
0.236
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.233
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.232
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
17 |
0.215
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.214
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.213
|
Human |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.212
|
Worm |
|
|
female meiosis i
|
GO:0007144 |
7 |
0.211
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.210
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.198
|
|
|
|
spindle assembly involved in meiosis
|
GO:0090306 |
4 |
0.196
|
Yeast Fly |
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.196
|
|
|
|
positive regulation of metaphase anaphase transition of cell cycle
|
GO:1902101 |
2 |
0.194
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.191
|
Human |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.187
|
Human |
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.184
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.184
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.179
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.174
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.173
|
Human |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.172
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.172
|
Human |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.168
|
Human |
|
|
cell cycle comprising mitosis without cytokinesis
|
GO:0033301 |
1 |
0.167
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
10 |
0.167
|
Worm Fly |
|
|
protein polymerization
|
GO:0051258 |
57 |
0.165
|
Fly |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.165
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.163
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.161
|
|
|
|
nuclear envelope organization
|
GO:0006998 |
11 |
0.160
|
Worm |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.157
|
Human Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.155
|
Human |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
20 |
0.154
|
Human |
|
|
cellularization
|
GO:0007349 |
1 |
0.151
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.148
|
Worm Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.146
|
Human |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.145
|
Human |
|
|
regulation of attachment of spindle microtubules to kinetochore
|
GO:0051988 |
3 |
0.143
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
21 |
0.140
|
Human |
|
|
germline cell cycle switching mitotic to meiotic cell cycle
|
GO:0051729 |
1 |
0.137
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.137
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.134
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.130
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.130
|
Yeast |
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.129
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.129
|
Human Mouse |
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.129
|
Fly |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.128
|
|
|
|
chromosome condensation
|
GO:0030261 |
10 |
0.125
|
|
|
|
male meiosis
|
GO:0007140 |
37 |
0.124
|
Fly |
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.123
|
Human |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.122
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.120
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.120
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.120
|
Human |
|
|
microtubule anchoring
|
GO:0034453 |
9 |
0.117
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.116
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.115
|
|
|
|
establishment of meiotic spindle orientation
|
GO:0051296 |
1 |
0.114
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
12 |
0.107
|
Human |
|
|
nuclear membrane organization
|
GO:0071763 |
4 |
0.107
|
|
|
|
spindle assembly involved in female meiosis
|
GO:0007056 |
3 |
0.107
|
Fly |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.107
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.105
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.105
|
|
|
|
dna conformation change
|
GO:0071103 |
37 |
0.105
|
|
|
|
positive regulation of exit from mitosis
|
GO:0031536 |
1 |
0.105
|
|
|
|
female meiotic division
|
GO:0007143 |
21 |
0.103
|
Rat Worm Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.103
|
Mouse |
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
9 |
0.103
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.103
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.101
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.100
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.100
|
Human |
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
20 |
0.100
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.100
|
|
|
|
reciprocal meiotic recombination
|
GO:0007131 |
16 |
0.097
|
Yeast |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.097
|
Human |
|
|
double strand break repair
|
GO:0006302 |
48 |
0.096
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.096
|
Human |
|
|
establishment of spindle orientation
|
GO:0051294 |
15 |
0.095
|
|
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
3 |
0.095
|
|
|
|
microtubule nucleation
|
GO:0007020 |
2 |
0.095
|
Fly |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.094
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.093
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.092
|
Human Worm |
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.092
|
Human |
|
|
positive regulation of mitosis
|
GO:0045840 |
14 |
0.090
|
Human |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.089
|
Human Yeast |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.089
|
|
|
|
regulation of nuclear cell cycle dna replication
|
GO:0033262 |
2 |
0.089
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.087
|
Human |
|
|
nucleus localization
|
GO:0051647 |
20 |
0.086
|
Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.086
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.084
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
24 |
0.082
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.081
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.081
|
Yeast Worm |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.081
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.081
|
Human |
|
|
meiosis ii
|
GO:0007135 |
7 |
0.080
|
Worm Fly |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.080
|
|
|
|
regulation of b cell tolerance induction
|
GO:0002661 |
2 |
0.080
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.079
|
Fly |
|
|
meiotic chromosome segregation
|
GO:0045132 |
19 |
0.079
|
Yeast Worm |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.079
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.079
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.078
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.077
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.077
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.076
|
|
|
|
nucleosome disassembly
|
GO:0006337 |
1 |
0.075
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.074
|
Yeast |
|
|
dna packaging
|
GO:0006323 |
30 |
0.073
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.072
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.071
|
|
|
|
nuclear dna replication
|
GO:0033260 |
3 |
0.071
|
|
|
|
centriole assembly
|
GO:0098534 |
6 |
0.071
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.071
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.070
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.069
|
Human |
|
|
fertilization
|
GO:0009566 |
127 |
0.068
|
Fly |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.068
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.068
|
Human |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.068
|
Human |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.067
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.066
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.066
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.066
|
Human |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.066
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.065
|
|
|
|
cyclin catabolic process
|
GO:0008054 |
1 |
0.065
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.064
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.064
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.064
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.063
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.063
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
12 |
0.062
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.062
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
15 |
0.062
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.062
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.061
|
Fly |
|
|
ventricular cardiac muscle cell development
|
GO:0055015 |
11 |
0.060
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.060
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.060
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
10 |
0.059
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.058
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.058
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.057
|
Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.057
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.057
|
Worm |
|
|
synapsis
|
GO:0007129 |
34 |
0.057
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
9 |
0.057
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.056
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.056
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.056
|
Human Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.056
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.054
|
Human |
|
|
regulation of cytokinesis
|
GO:0032465 |
5 |
0.052
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.052
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.052
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.051
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.051
|
Worm |
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.051
|
|
|
|
membrane disassembly
|
GO:0030397 |
1 |
0.050
|
Worm |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.050
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.049
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.049
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.049
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.049
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
22 |
0.049
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.049
|
|
|
|
translesion synthesis
|
GO:0019985 |
1 |
0.048
|
|
|
|
spindle assembly involved in female meiosis i
|
GO:0007057 |
2 |
0.048
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.048
|
Human |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.047
|
Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.046
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.046
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.046
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.046
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.045
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.045
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.045
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.044
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.044
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.044
|
Human |
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.043
|
Fly |
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.042
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.042
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.042
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.041
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.041
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.041
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.041
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.041
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.040
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.040
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.040
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.040
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.040
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.040
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.040
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.040
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.040
|
Human |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.040
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.039
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.039
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.039
|
Human |
|
|
protein import
|
GO:0017038 |
101 |
0.039
|
|
|
|
chromatin remodeling at centromere
|
GO:0031055 |
2 |
0.039
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.039
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.038
|
|
|
|
chromosome separation
|
GO:0051304 |
14 |
0.038
|
Human Yeast |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.038
|
Mouse |
|
|
nuclear migration
|
GO:0007097 |
6 |
0.038
|
Fly |
|
|
protein targeting
|
GO:0006605 |
143 |
0.038
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.037
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.037
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
24 |
0.036
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.036
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.036
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.036
|
Human |
|
|
negative regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032435 |
15 |
0.036
|
Human |
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
9 |
0.035
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.035
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.035
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.035
|
Human Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.035
|
|
|
|
positive regulation of ubiquitin protein transferase activity
|
GO:0051443 |
4 |
0.034
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.034
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.034
|
|
|
|
cellular response to sterol depletion
|
GO:0071501 |
4 |
0.034
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.034
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.033
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.033
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.033
|
Human |
|
|
protein localization to chromosome
|
GO:0034502 |
6 |
0.032
|
Human |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.032
|
Human |
|
|
protein localization to chromosome centromeric region
|
GO:0071459 |
1 |
0.032
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.032
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.032
|
|
|
|
regulation of ran gtpase activity
|
GO:0032316 |
3 |
0.032
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.032
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.032
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.032
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.031
|
|
|
|
negative regulation of centrosome duplication
|
GO:0010826 |
4 |
0.031
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.031
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.031
|
Worm Fly |
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.031
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
20 |
0.031
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.030
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.030
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.030
|
Human |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.030
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.030
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.030
|
Human |
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.030
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.030
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.030
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.030
|
|
|
|
protein localization to nuclear envelope
|
GO:0090435 |
2 |
0.030
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.029
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.029
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.029
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
7 |
0.029
|
Human |
|
|
regulation of dephosphorylation
|
GO:0035303 |
18 |
0.029
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.029
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.029
|
Human |
|
|
nucleus organization
|
GO:0006997 |
45 |
0.029
|
Worm Fly |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.029
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.028
|
|
|
|
srebp signaling pathway
|
GO:0032933 |
4 |
0.028
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.028
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.028
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.028
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
57 |
0.028
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.028
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.028
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.028
|
|
|
|
negative regulation of cell aging
|
GO:0090344 |
5 |
0.028
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.028
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.027
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.027
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.027
|
|
|
|
response to iron ion
|
GO:0010039 |
4 |
0.027
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.027
|
|
|
|
microtubule polymerization
|
GO:0046785 |
12 |
0.027
|
Fly |
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.026
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.026
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.026
|
Fly |
|
|
dna dependent dna replication maintenance of fidelity
|
GO:0045005 |
3 |
0.026
|
|
|
|
positive regulation of nfat protein import into nucleus
|
GO:0051533 |
1 |
0.026
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.026
|
Worm Fly |
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
23 |
0.026
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.026
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.026
|
Worm |
|
|
tube closure
|
GO:0060606 |
91 |
0.025
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.025
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.025
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.025
|
Human |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.025
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.025
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.025
|
Human |
|
|
genitalia development
|
GO:0048806 |
37 |
0.025
|
Worm |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.025
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.025
|
Mouse Fly |
|
|
synaptonemal complex assembly
|
GO:0007130 |
13 |
0.025
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.025
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.024
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.024
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.024
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.024
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.024
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.024
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.024
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
8 |
0.024
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.024
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.023
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.023
|
Human |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.023
|
|
|
|
histone threonine phosphorylation
|
GO:0035405 |
1 |
0.023
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.023
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.023
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.022
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.022
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.022
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.022
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.022
|
|
|
|
regulation of asymmetric cell division
|
GO:0009786 |
4 |
0.022
|
|
|
|
regulation of double strand break repair via homologous recombination
|
GO:0010569 |
2 |
0.021
|
|
|
|
positive regulation of mitotic cell cycle embryonic
|
GO:0045977 |
2 |
0.021
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.021
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.021
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.021
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.021
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.021
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.020
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.020
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.020
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.020
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.020
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.020
|
|
|
|
regulation of double strand break repair via nonhomologous end joining
|
GO:2001032 |
2 |
0.020
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.020
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.020
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.019
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
9 |
0.019
|
Human |
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.019
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.019
|
|
|
|
meiotic spindle organization
|
GO:0000212 |
9 |
0.019
|
Yeast Fly |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.019
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.019
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
8 |
0.019
|
Human |
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.018
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.018
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.018
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.018
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.018
|
|
|
|
cell cycle switching mitotic to meiotic cell cycle
|
GO:0051728 |
1 |
0.018
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
31 |
0.018
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.018
|
|
|
|
positive regulation of oocyte maturation
|
GO:1900195 |
2 |
0.018
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.018
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.018
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.017
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.017
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.017
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.017
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.017
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.017
|
Human |
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.017
|
Human |
|
|
protein processing
|
GO:0016485 |
163 |
0.017
|
Human |
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.017
|
Human |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.017
|
|
|
|
synaptonemal complex organization
|
GO:0070193 |
15 |
0.017
|
Yeast |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.017
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.017
|
Mouse |
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.017
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
19 |
0.016
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.016
|
|
|
|
negative regulation of binding
|
GO:0051100 |
39 |
0.016
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.016
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
7 |
0.016
|
Human |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.016
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
58 |
0.016
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.016
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.016
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.015
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.015
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.015
|
|
|
|
exit from mitosis
|
GO:0010458 |
3 |
0.015
|
|
