Mus musculus

26 known processes

Pmel

premelanosome protein

(Aliases: Silv,D10H12S53E,gp100,Pmel17,Si,gp87,D12S53Eh)

Pmel biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
secondary metabolite biosynthetic process GO:0044550 11 0.826
ketone body metabolic process GO:1902224 3 0.795
melanosome organization GO:0032438 8 0.683
melanin biosynthetic process GO:0042438 10 0.668
pigment biosynthetic process GO:0046148 26 0.579
pigmentation GO:0043473 71 0.533
tyrosine metabolic process GO:0006570 4 0.526
cellular amino acid metabolic process GO:0006520 103 0.506
short chain fatty acid metabolic process GO:0046459 6 0.387
pigment granule localization GO:0051875 13 0.261
gland development GO:0048732 330 0.247
alpha amino acid metabolic process GO:1901605 59 0.240
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.239
developmental pigmentation GO:0048066 40 0.234
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.216
melanocyte differentiation GO:0030318 25 0.201
spermatogenesis GO:0007283 284 0.201
cell division GO:0051301 120 0.200
positive regulation of cell development GO:0010720 237 0.185
transmembrane transport GO:0055085 412 0.183
cellular pigmentation GO:0033059 20 0.161
negative regulation of cell proliferation GO:0008285 296 0.161
regulation of kinase activity GO:0043549 249 0.148
positive regulation of cellular amine metabolic process GO:0033240 5 0.147
synaptic transmission GO:0007268 329 0.140
phenol containing compound biosynthetic process GO:0046189 21 0.138
negative regulation of phosphorus metabolic process GO:0010563 184 0.138
regulation of cellular amino acid metabolic process GO:0006521 5 0.137
forebrain development GO:0030900 302 0.128
ribonucleoside catabolic process GO:0042454 206 0.126
leukocyte differentiation GO:0002521 342 0.124
regulation of transferase activity GO:0051338 263 0.122
neural precursor cell proliferation GO:0061351 121 0.117
stem cell proliferation GO:0072089 117 0.107
nucleoside metabolic process GO:0009116 246 0.106
secondary metabolic process GO:0019748 18 0.106
phenol containing compound metabolic process GO:0018958 60 0.105
nucleobase containing small molecule metabolic process GO:0055086 352 0.100
regulation of cellular amine metabolic process GO:0033238 20 0.099
meiotic cell cycle GO:0051321 122 0.097
aromatic amino acid family metabolic process GO:0009072 9 0.097
spermatid development GO:0007286 108 0.096
negative regulation of cellular protein metabolic process GO:0032269 247 0.095
male gamete generation GO:0048232 285 0.094
alpha beta t cell activation GO:0046631 91 0.090
respiratory tube development GO:0030323 167 0.090
coagulation GO:0050817 78 0.089
dna metabolic process GO:0006259 303 0.088
vesicle organization GO:0016050 60 0.087
cellular lipid metabolic process GO:0044255 323 0.086
cation transmembrane transport GO:0098655 266 0.085
secretory granule organization GO:0033363 20 0.085
nucleoside phosphate metabolic process GO:0006753 338 0.085
cellular amine metabolic process GO:0044106 44 0.081
pigment granule organization GO:0048753 9 0.081
organonitrogen compound biosynthetic process GO:1901566 192 0.079
blood coagulation GO:0007596 76 0.079
lytic vacuole organization GO:0080171 21 0.078
positive regulation of kinase activity GO:0033674 155 0.077
germ cell development GO:0007281 185 0.077
vesicle localization GO:0051648 86 0.076
pigment cell differentiation GO:0050931 27 0.076
organic anion transport GO:0015711 137 0.075
cellular ion homeostasis GO:0006873 165 0.075
t cell activation GO:0042110 289 0.074
regulation of protein serine threonine kinase activity GO:0071900 157 0.071
regulation of protein kinase activity GO:0045859 232 0.070
ribonucleoside metabolic process GO:0009119 245 0.070
aromatic compound catabolic process GO:0019439 286 0.070
establishment of melanosome localization GO:0032401 11 0.069
purine nucleotide metabolic process GO:0006163 302 0.067
cell fate commitment GO:0045165 210 0.067
sensory organ morphogenesis GO:0090596 242 0.067
inorganic cation transmembrane transport GO:0098662 207 0.065
wnt signaling pathway GO:0016055 188 0.065
forebrain ventricular zone progenitor cell division GO:0021869 6 0.065
nucleotide metabolic process GO:0009117 332 0.065
heterocycle catabolic process GO:0046700 280 0.064
connective tissue development GO:0061448 179 0.063
positive regulation of protein phosphorylation GO:0001934 242 0.062
negative regulation of protein metabolic process GO:0051248 282 0.062
microtubule based process GO:0007017 236 0.061
ribonucleoside triphosphate metabolic process GO:0009199 220 0.061
monocarboxylic acid metabolic process GO:0032787 191 0.061
ion transmembrane transport GO:0034220 361 0.060
epithelial cell development GO:0002064 159 0.060
organic hydroxy compound metabolic process GO:1901615 203 0.059
stem cell development GO:0048864 219 0.058
ribonucleotide metabolic process GO:0009259 291 0.058
purine containing compound metabolic process GO:0072521 311 0.058
cellular potassium ion transport GO:0071804 43 0.057
multicellular organismal homeostasis GO:0048871 164 0.057
phototransduction GO:0007602 17 0.056
retina development in camera type eye GO:0060041 119 0.056
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.056
forebrain generation of neurons GO:0021872 63 0.055
skin development GO:0043588 220 0.055
negative regulation of molecular function GO:0044092 258 0.054
meiotic nuclear division GO:0007126 115 0.054
cellular response to organonitrogen compound GO:0071417 145 0.053
carbohydrate derivative biosynthetic process GO:1901137 183 0.053
regulation of neural precursor cell proliferation GO:2000177 70 0.052
b cell activation GO:0042113 161 0.052
neuronal stem cell division GO:0036445 10 0.052
generation of precursor metabolites and energy GO:0006091 103 0.051
glycosyl compound metabolic process GO:1901657 246 0.051
embryonic organ morphogenesis GO:0048562 276 0.050
mitochondrion organization GO:0007005 134 0.049
sulfur compound metabolic process GO:0006790 100 0.049
protein processing GO:0016485 163 0.049
organic cyclic compound catabolic process GO:1901361 295 0.048
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
cellular ketone metabolic process GO:0042180 84 0.048
positive regulation of cell death GO:0010942 224 0.048
phospholipid metabolic process GO:0006644 87 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.047
leukocyte proliferation GO:0070661 172 0.046
pigment metabolic process GO:0042440 32 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.046
negative regulation of epithelial cell proliferation GO:0050680 64 0.046
regulation of ion transport GO:0043269 215 0.045
cellular nitrogen compound catabolic process GO:0044270 280 0.045
melanosome transport GO:0032402 11 0.045
locomotory behavior GO:0007626 195 0.044
cytoplasmic transport GO:0016482 234 0.044
positive regulation of mapk cascade GO:0043410 170 0.044
positive regulation of protein kinase activity GO:0045860 144 0.043
wound healing GO:0042060 157 0.043
rhythmic process GO:0048511 174 0.043
negative regulation of lymphocyte activation GO:0051250 91 0.043
establishment of organelle localization GO:0051656 122 0.043
regulation of hydrolase activity GO:0051336 246 0.042
melanosome localization GO:0032400 12 0.042
cellular chemical homeostasis GO:0055082 215 0.041
melanin metabolic process GO:0006582 12 0.041
activation of immune response GO:0002253 138 0.041
regulation of lymphocyte activation GO:0051249 240 0.041
amine metabolic process GO:0009308 45 0.040
skeletal system development GO:0001501 356 0.040
negative regulation of sterol transport GO:0032372 4 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
microtubule cytoskeleton organization GO:0000226 157 0.039
positive regulation of map kinase activity GO:0043406 84 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
positive regulation of transferase activity GO:0051347 167 0.039
response to light stimulus GO:0009416 135 0.038
positive regulation of apoptotic process GO:0043065 217 0.037
regulation of map kinase activity GO:0043405 120 0.037
regulation of cell cycle process GO:0010564 160 0.037
negative regulation of protein phosphorylation GO:0001933 126 0.037
lipid localization GO:0010876 126 0.036
positive regulation of programmed cell death GO:0043068 218 0.036
stem cell division GO:0017145 30 0.036
multicellular organism growth GO:0035264 161 0.036
neuronal action potential GO:0019228 54 0.036
cation transport GO:0006812 399 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.034
regulation of cellular response to stress GO:0080135 159 0.034
regulation of cell activation GO:0050865 289 0.034
regulation of proteolysis GO:0030162 164 0.034
nuclear division GO:0000280 158 0.033
regulation of heart contraction GO:0008016 77 0.033
cardiac chamber morphogenesis GO:0003206 93 0.033
stem cell differentiation GO:0048863 268 0.033
lysosome organization GO:0007040 21 0.033
positive regulation of nervous system development GO:0051962 221 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.032
purine nucleotide catabolic process GO:0006195 211 0.032
ras protein signal transduction GO:0007265 77 0.032
negative regulation of protein modification process GO:0031400 163 0.032
feeding behavior GO:0007631 62 0.032
muscle system process GO:0003012 141 0.032
cellular divalent inorganic cation homeostasis GO:0072503 127 0.032
molting cycle GO:0042303 90 0.032
purine containing compound catabolic process GO:0072523 213 0.032
protein maturation GO:0051604 176 0.031
epidermis development GO:0008544 187 0.031
apoptotic signaling pathway GO:0097190 306 0.031
ear morphogenesis GO:0042471 118 0.031
neuroblast differentiation GO:0014016 2 0.031
gonad development GO:0008406 141 0.031
neuroblast division GO:0055057 10 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
muscle cell differentiation GO:0042692 261 0.030
glial cell differentiation GO:0010001 131 0.030
positive regulation of proteolysis GO:0045862 85 0.030
regulation of endopeptidase activity GO:0052548 89 0.030
regulation of peptidase activity GO:0052547 96 0.030
peptidyl serine modification GO:0018209 83 0.030
negative regulation of cholesterol transport GO:0032375 4 0.030
positive regulation of nucleotide metabolic process GO:0045981 114 0.030
embryonic limb morphogenesis GO:0030326 126 0.030
fatty acid metabolic process GO:0006631 121 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
calcium ion homeostasis GO:0055074 127 0.029
respiratory system development GO:0060541 190 0.029
negative regulation of protein processing GO:0010955 79 0.029
camera type eye development GO:0043010 266 0.029
organelle fission GO:0048285 170 0.029
negative regulation of t cell activation GO:0050868 65 0.028
genetic imprinting GO:0071514 27 0.028
organic acid transport GO:0015849 101 0.028
regulation of reactive oxygen species metabolic process GO:2000377 40 0.028
heart morphogenesis GO:0003007 178 0.028
negative regulation of kinase activity GO:0033673 81 0.028
development of primary sexual characteristics GO:0045137 143 0.027
amino acid transmembrane transport GO:0003333 37 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
positive regulation of protein modification process GO:0031401 299 0.027
cellular carbohydrate metabolic process GO:0044262 119 0.027
nitrogen compound transport GO:0071705 271 0.027
rho protein signal transduction GO:0007266 32 0.027
t cell differentiation GO:0030217 174 0.027
regulation of cell cycle GO:0051726 281 0.027
regulation of mapk cascade GO:0043408 248 0.026
regulation of leukocyte mediated immunity GO:0002703 104 0.026
regulation of homeostatic process GO:0032844 182 0.026
cation homeostasis GO:0055080 212 0.026
cellular component assembly involved in morphogenesis GO:0010927 139 0.026
cell substrate adhesion GO:0031589 130 0.026
leukocyte mediated immunity GO:0002443 174 0.026
cellular response to biotic stimulus GO:0071216 92 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
cellular response to molecule of bacterial origin GO:0071219 83 0.026
organic hydroxy compound biosynthetic process GO:1901617 77 0.026
homeostasis of number of cells GO:0048872 210 0.026
immune effector process GO:0002252 321 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
lung development GO:0030324 164 0.025
lymphocyte mediated immunity GO:0002449 139 0.025
epithelial tube morphogenesis GO:0060562 303 0.025
cell activation involved in immune response GO:0002263 126 0.025
digestive tract development GO:0048565 190 0.025
response to organonitrogen compound GO:0010243 246 0.025
regionalization GO:0003002 337 0.025
oxidation reduction process GO:0055114 342 0.025
smooth muscle contraction GO:0006939 44 0.025
organelle assembly GO:0070925 177 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
lymphocyte activation involved in immune response GO:0002285 93 0.025
mapk cascade GO:0000165 281 0.025
negative regulation of hydrolase activity GO:0051346 71 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
single fertilization GO:0007338 82 0.024
reactive oxygen species biosynthetic process GO:1903409 8 0.024
microtubule based movement GO:0007018 84 0.024
myeloid cell homeostasis GO:0002262 114 0.024
nucleoside catabolic process GO:0009164 206 0.024
forebrain neuroblast division GO:0021873 9 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.024
monosaccharide transport GO:0015749 58 0.024
macromolecule catabolic process GO:0009057 281 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
blood vessel morphogenesis GO:0048514 285 0.024
positive regulation of lymphocyte activation GO:0051251 140 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.024
blood circulation GO:0008015 195 0.023
detection of stimulus GO:0051606 84 0.023
negative regulation of protein maturation GO:1903318 79 0.023
phototransduction visible light GO:0007603 6 0.023
organophosphate catabolic process GO:0046434 232 0.023
detection of external stimulus GO:0009581 61 0.023
anion transport GO:0006820 177 0.023
peptidyl amino acid modification GO:0018193 336 0.023
heart contraction GO:0060047 93 0.023
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.023
cellular homeostasis GO:0019725 240 0.022
positive regulation of cellular catabolic process GO:0031331 148 0.022
cartilage development GO:0051216 140 0.022
morphogenesis of a branching structure GO:0001763 203 0.022
tissue homeostasis GO:0001894 115 0.022
metal ion homeostasis GO:0055065 189 0.022
hair cycle GO:0042633 90 0.022
negative regulation of nervous system development GO:0051961 156 0.022
pigment granule transport GO:0051904 12 0.022
neuroepithelial cell differentiation GO:0060563 37 0.022
glycoprotein metabolic process GO:0009100 116 0.022
neuroblast proliferation GO:0007405 49 0.022
retinal blood vessel morphogenesis GO:0061304 3 0.022
regulation of protein processing GO:0070613 96 0.022
gas homeostasis GO:0033483 3 0.022
nucleotide catabolic process GO:0009166 217 0.021
photoreceptor cell development GO:0042461 40 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
peptide secretion GO:0002790 114 0.021
glial cell development GO:0021782 54 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
negative regulation of transferase activity GO:0051348 85 0.021
glucose homeostasis GO:0042593 128 0.021
multi multicellular organism process GO:0044706 109 0.021
lipid transport GO:0006869 98 0.021
cellular response to abiotic stimulus GO:0071214 56 0.021
actin cytoskeleton organization GO:0030036 220 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
vacuole organization GO:0007033 38 0.021
peptidyl tyrosine modification GO:0018212 145 0.021
purine nucleoside catabolic process GO:0006152 205 0.020
anatomical structure homeostasis GO:0060249 145 0.020
natural killer cell activation GO:0030101 44 0.020
developmental maturation GO:0021700 193 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
meiosis i GO:0007127 60 0.020
spermatid differentiation GO:0048515 115 0.020
interleukin 8 secretion GO:0072606 3 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
regulation of membrane potential GO:0042391 192 0.020
purine containing compound biosynthetic process GO:0072522 70 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
cytokine mediated signaling pathway GO:0019221 115 0.019
activation of mapk activity GO:0000187 59 0.019
rhodopsin mediated signaling pathway GO:0016056 4 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
cellularization GO:0007349 1 0.019
hemostasis GO:0007599 78 0.019
lymphocyte differentiation GO:0030098 242 0.019
chromosome organization involved in meiosis GO:0070192 39 0.019
somatic stem cell division GO:0048103 19 0.019
positive regulation of gtpase activity GO:0043547 85 0.019
sensory perception GO:0007600 245 0.018
regulation of feeding behavior GO:0060259 3 0.018
dna recombination GO:0006310 92 0.018
aminoglycan metabolic process GO:0006022 34 0.018
protein localization to nucleus GO:0034504 121 0.018
carbohydrate transport GO:0008643 62 0.018
regulation of secretion by cell GO:1903530 249 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
regulation of protein maturation GO:1903317 96 0.018
adult locomotory behavior GO:0008344 91 0.018
regulation of neuroblast proliferation GO:1902692 27 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
cyclic purine nucleotide metabolic process GO:0052652 43 0.018
blastocyst development GO:0001824 80 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
positive regulation of protein transport GO:0051222 93 0.018
cyclic nucleotide metabolic process GO:0009187 59 0.018
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.018
dopamine metabolic process GO:0042417 23 0.018
epithelial cell proliferation GO:0050673 174 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.018
progesterone secretion GO:0042701 1 0.018
positive regulation of growth GO:0045927 104 0.017
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.017
ossification GO:0001503 216 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
metanephric loop of henle development GO:0072236 4 0.017
transition metal ion transport GO:0000041 38 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
meiotic cell cycle process GO:1903046 77 0.017
adaptive immune response GO:0002250 155 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
regulation of body fluid levels GO:0050878 162 0.017
cellular magnesium ion homeostasis GO:0010961 3 0.017
adult behavior GO:0030534 135 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
pigment accumulation GO:0043476 1 0.016
regulation of cell migration GO:0030334 219 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
sensory perception of chemical stimulus GO:0007606 51 0.016
defecation GO:0030421 1 0.016
organelle localization GO:0051640 179 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
dephosphorylation GO:0016311 129 0.016
gliogenesis GO:0042063 141 0.016
regulation of adaptive immune response GO:0002819 90 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
negative regulation of growth GO:0045926 99 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
cytokine production GO:0001816 319 0.016
leukocyte migration GO:0050900 124 0.016
cellular protein catabolic process GO:0044257 155 0.016
positive regulation of secretion GO:0051047 130 0.016
acetylcholine transport GO:0015870 2 0.016
transmission of nerve impulse GO:0019226 76 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.016
inflammatory response GO:0006954 244 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
glycoprotein biosynthetic process GO:0009101 89 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
defense response to bacterium GO:0042742 119 0.016
regulation of secretion GO:0051046 274 0.016
lymphocyte proliferation GO:0046651 164 0.016
cell adhesion GO:0007155 329 0.016
Mouse
negative regulation of organelle organization GO:0010639 90 0.016
ear development GO:0043583 200 0.016
detection of abiotic stimulus GO:0009582 60 0.016
positive regulation of immune effector process GO:0002699 107 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
response to iron ion GO:0010039 4 0.015
potassium ion transport GO:0006813 52 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
regulation of system process GO:0044057 200 0.015
positive regulation of cell cycle GO:0045787 92 0.015
erythrocyte differentiation GO:0030218 88 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
carboxylic acid transport GO:0046942 100 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.015
response to acid chemical GO:0001101 111 0.015
endothelial cell differentiation GO:0045446 41 0.015
fertilization GO:0009566 127 0.015
digestion GO:0007586 40 0.015
single organism cell adhesion GO:0098602 156 0.015
regulation of protein localization GO:0032880 231 0.015
erk1 and erk2 cascade GO:0070371 77 0.015
regulation of hepatocyte differentiation GO:0070366 2 0.015
regulation of stem cell proliferation GO:0072091 78 0.015
striated muscle cell development GO:0055002 125 0.015
negative regulation of meiotic cell cycle phase transition GO:1901994 3 0.015
cell type specific apoptotic process GO:0097285 268 0.015
binding of sperm to zona pellucida GO:0007339 34 0.015
regulation of muscle contraction GO:0006937 49 0.015
regulation of protein catabolic process GO:0042176 108 0.015
circulatory system process GO:0003013 197 0.015
regulation of response to wounding GO:1903034 189 0.015
lung epithelial cell differentiation GO:0060487 29 0.015
regulation of cell adhesion GO:0030155 154 0.015
lymphocyte homeostasis GO:0002260 64 0.015
regulation of sterol transport GO:0032371 17 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
negative regulation of endopeptidase activity GO:0010951 44 0.015
synaptic transmission involved in micturition GO:0060084 3 0.015
negative regulation of immune system process GO:0002683 209 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
regulation of circadian rhythm GO:0042752 58 0.015
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
photoreceptor cell differentiation GO:0046530 52 0.015
mesenchymal cell development GO:0014031 93 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
tissue remodeling GO:0048771 102 0.015
lipid homeostasis GO:0055088 63 0.015
cellular metal ion homeostasis GO:0006875 151 0.014
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.014
regulation of hormone levels GO:0010817 211 0.014
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.014
extracellular structure organization GO:0043062 148 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
regulation of neuron differentiation GO:0045664 281 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
carbohydrate metabolic process GO:0005975 230 0.014
protein catabolic process GO:0030163 221 0.014
rna processing GO:0006396 105 0.014
platelet activation GO:0030168 40 0.014
retina homeostasis GO:0001895 23 0.014
regulation of cell division GO:0051302 76 0.014
endocytosis GO:0006897 168 0.014
leukocyte apoptotic process GO:0071887 71 0.014
regulation of protein transport GO:0051223 163 0.014
response to extracellular stimulus GO:0009991 127 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
proteoglycan metabolic process GO:0006029 38 0.014
sensory perception of light stimulus GO:0050953 54 0.014
regulation of protein complex assembly GO:0043254 83 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
cardiac chamber development GO:0003205 108 0.013
bone development GO:0060348 120 0.013
regulation of anatomical structure size GO:0090066 178 0.013
hexose transport GO:0008645 56 0.013
regulation of muscle system process GO:0090257 80 0.013
positive regulation of ion transport GO:0043270 65 0.013
lateral geniculate nucleus development GO:0021771 1 0.013
smoothened signaling pathway GO:0007224 105 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.013
mast cell proliferation GO:0070662 4 0.013
regulation of blood circulation GO:1903522 93 0.013
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.013
response to organic cyclic compound GO:0014070 198 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
interleukin 8 production GO:0032637 4 0.013
subpallium neuron fate commitment GO:0060163 2 0.013
endothelial cell development GO:0001885 20 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
cellular protein complex assembly GO:0043623 116 0.013
protein glycosylation GO:0006486 55 0.013

Pmel disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.057
retinal degeneration DOID:8466 0 0.057
sensory system disease DOID:0050155 0 0.057
disease of anatomical entity DOID:7 0 0.057
retinitis pigmentosa DOID:10584 0 0.057
eye and adnexa disease DOID:1492 0 0.057
nervous system disease DOID:863 0 0.057
eye disease DOID:5614 0 0.057
bone disease DOID:0080001 0 0.027
musculoskeletal system disease DOID:17 0 0.027
connective tissue disease DOID:65 0 0.027
bone development disease DOID:0080006 0 0.027
osteochondrodysplasia DOID:2256 0 0.017
dysostosis DOID:1934 0 0.013