Mus musculus

23 known processes

Pmp22

peripheral myelin protein 22

(Aliases: HNPP,trembler,Tr,Gas-3,22kDa)

Pmp22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 281 0.298
extracellular structure organization GO:0043062 148 0.268
negative regulation of protein metabolic process GO:0051248 282 0.265
regulation of peptidase activity GO:0052547 96 0.246
negative regulation of molecular function GO:0044092 258 0.219
regulation of mapk cascade GO:0043408 248 0.204
response to growth factor GO:0070848 198 0.198
regulation of hydrolase activity GO:0051336 246 0.194
myelination GO:0042552 74 0.179
negative regulation of vasculature development GO:1901343 26 0.163
regulation of transferase activity GO:0051338 263 0.162
gland development GO:0048732 330 0.160
regulation of map kinase activity GO:0043405 120 0.159
cation transport GO:0006812 399 0.151
negative regulation of hydrolase activity GO:0051346 71 0.149
positive regulation of protein modification process GO:0031401 299 0.148
neuronal action potential GO:0019228 54 0.141
ensheathment of neurons GO:0007272 76 0.135
extracellular matrix organization GO:0030198 147 0.129
positive regulation of mapk cascade GO:0043410 170 0.126
skeletal muscle organ development GO:0060538 163 0.114
multicellular organismal signaling GO:0035637 91 0.113
regulation of protein maturation GO:1903317 96 0.112
regulation of protein serine threonine kinase activity GO:0071900 157 0.111
negative regulation of proteolysis GO:0045861 74 0.108
heart process GO:0003015 94 0.103
regulation of proteolysis GO:0030162 164 0.101
cellular amino acid metabolic process GO:0006520 103 0.092
response to peptide hormone GO:0043434 127 0.090
negative regulation of endopeptidase activity GO:0010951 44 0.090
cellular ketone metabolic process GO:0042180 84 0.089
protein localization to plasma membrane GO:0072659 57 0.087
Mouse
negative regulation of protein processing GO:0010955 79 0.086
muscle cell differentiation GO:0042692 261 0.086
response to peptide GO:1901652 136 0.083
response to inorganic substance GO:0010035 96 0.081
regulation of endopeptidase activity GO:0052548 89 0.080
positive regulation of programmed cell death GO:0043068 218 0.080
cell junction organization GO:0034330 77 0.080
respiratory system development GO:0060541 190 0.080
muscle tissue development GO:0060537 308 0.078
negative regulation of cellular protein metabolic process GO:0032269 247 0.078
wound healing GO:0042060 157 0.077
cell adhesion GO:0007155 329 0.077
Mouse
glial cell differentiation GO:0010001 131 0.077
epithelial cell development GO:0002064 159 0.076
axon ensheathment GO:0008366 76 0.075
positive regulation of cellular amine metabolic process GO:0033240 5 0.075
circulatory system process GO:0003013 197 0.075
cellular amine metabolic process GO:0044106 44 0.073
blood vessel morphogenesis GO:0048514 285 0.072
negative regulation of peptidase activity GO:0010466 46 0.070
metanephric part of ureteric bud development GO:0035502 2 0.070
response to oxygen levels GO:0070482 62 0.069
peptidyl amino acid modification GO:0018193 336 0.068
negative regulation of phagocytosis GO:0050765 4 0.067
wnt signaling pathway GO:0016055 188 0.067
blood coagulation GO:0007596 76 0.067
cellular response to growth factor stimulus GO:0071363 197 0.067
cell growth GO:0016049 130 0.066
negative regulation of cell proliferation GO:0008285 296 0.064
protein maturation GO:0051604 176 0.064
regulation of kinase activity GO:0043549 249 0.064
regulation of cellular ketone metabolic process GO:0010565 66 0.063
single organism cell adhesion GO:0098602 156 0.061
regulation of binding GO:0051098 111 0.060
canonical wnt signaling pathway GO:0060070 130 0.059
urogenital system development GO:0001655 261 0.058
action potential GO:0001508 78 0.058
small gtpase mediated signal transduction GO:0007264 97 0.058
response to organic cyclic compound GO:0014070 198 0.058
positive regulation of protein phosphorylation GO:0001934 242 0.057
striated muscle cell development GO:0055002 125 0.057
membrane organization GO:0061024 245 0.056
Mouse
negative regulation of protein maturation GO:1903318 79 0.054
positive regulation of apoptotic process GO:0043065 217 0.054
bone development GO:0060348 120 0.054
regulation of angiogenesis GO:0045765 81 0.053
response to alcohol GO:0097305 48 0.053
nucleotide metabolic process GO:0009117 332 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
positive regulation of cell motility GO:2000147 116 0.052
cell cell junction organization GO:0045216 72 0.052
response to organonitrogen compound GO:0010243 246 0.051
response to radiation GO:0009314 165 0.050
response to decreased oxygen levels GO:0036293 59 0.050
regulation of protein processing GO:0070613 96 0.049
hemostasis GO:0007599 78 0.049
regulation of membrane potential GO:0042391 192 0.049
protein processing GO:0016485 163 0.048
ossification GO:0001503 216 0.048
respiratory tube development GO:0030323 167 0.047
gliogenesis GO:0042063 141 0.047
skeletal system development GO:0001501 356 0.047
bmp signaling pathway GO:0030509 93 0.046
transmission of nerve impulse GO:0019226 76 0.046
regulation of protein kinase activity GO:0045859 232 0.046
schwann cell differentiation GO:0014037 26 0.045
regulation of protein binding GO:0043393 60 0.045
negative regulation of protein phosphorylation GO:0001933 126 0.045
endomembrane system organization GO:0010256 147 0.045
Mouse
mapk cascade GO:0000165 281 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.044
angiogenesis GO:0001525 201 0.044
regulation of neuron differentiation GO:0045664 281 0.044
cellular lipid metabolic process GO:0044255 323 0.044
camera type eye development GO:0043010 266 0.043
regulation of intracellular transport GO:0032386 159 0.043
membrane fusion GO:0061025 38 0.043
peripheral nervous system development GO:0007422 53 0.042
metal ion homeostasis GO:0055065 189 0.042
aromatic compound catabolic process GO:0019439 286 0.041
apical constriction GO:0003383 4 0.041
regulation of organelle organization GO:0033043 289 0.041
positive regulation of cell death GO:0010942 224 0.041
ribose phosphate metabolic process GO:0019693 291 0.040
striated muscle tissue development GO:0014706 293 0.040
cellular divalent inorganic cation homeostasis GO:0072503 127 0.040
calcium ion homeostasis GO:0055074 127 0.040
mitotic cell cycle GO:0000278 195 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
divalent inorganic cation homeostasis GO:0072507 138 0.039
reactive oxygen species metabolic process GO:0072593 84 0.039
nuclear transport GO:0051169 139 0.038
glial cell development GO:0021782 54 0.038
transmembrane transport GO:0055085 412 0.037
t cell activation GO:0042110 289 0.037
regulation of system process GO:0044057 200 0.037
regulation of mitotic cell cycle GO:0007346 126 0.037
regulation of body fluid levels GO:0050878 162 0.037
regulation of cell adhesion GO:0030155 154 0.036
Mouse
intracellular protein transport GO:0006886 204 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.036
cardiac muscle cell differentiation GO:0055007 69 0.035
plasma membrane organization GO:0007009 90 0.035
Mouse
glycoprotein metabolic process GO:0009100 116 0.035
cell type specific apoptotic process GO:0097285 268 0.034
regulation of establishment of protein localization GO:0070201 181 0.034
establishment of protein localization to plasma membrane GO:0090002 34 0.034
regulation of cytoplasmic transport GO:1903649 112 0.034
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.034
regulation of vasculature development GO:1901342 88 0.034
negative regulation of cell cycle GO:0045786 123 0.034
chemotaxis GO:0006935 247 0.033
protein hydroxylation GO:0018126 4 0.033
response to hypoxia GO:0001666 58 0.032
defense response to other organism GO:0098542 197 0.032
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.032
regulation of cell motility GO:2000145 236 0.032
cellular calcium ion homeostasis GO:0006874 119 0.032
regulation of protein localization GO:0032880 231 0.032
response to insulin GO:0032868 100 0.032
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
organophosphate catabolic process GO:0046434 232 0.031
cilium morphogenesis GO:0060271 102 0.031
positive regulation of intracellular transport GO:0032388 70 0.031
regulation of homeostatic process GO:0032844 182 0.031
actin cytoskeleton organization GO:0030036 220 0.030
blood circulation GO:0008015 195 0.030
regulation of epithelial cell proliferation GO:0050678 141 0.030
g1 s transition of mitotic cell cycle GO:0000082 57 0.030
positive regulation of cell migration GO:0030335 109 0.030
activation of mapk activity GO:0000187 59 0.030
mitotic cell cycle process GO:1903047 159 0.030
regulation of canonical wnt signaling pathway GO:0060828 82 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
positive regulation of growth GO:0045927 104 0.029
regulation of wnt signaling pathway GO:0030111 123 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.028
organic hydroxy compound transport GO:0015850 93 0.028
regulation of cell cycle process GO:0010564 160 0.028
regulation of cellular response to stress GO:0080135 159 0.028
renal system development GO:0072001 225 0.028
cellular chemical homeostasis GO:0055082 215 0.028
establishment of protein localization to membrane GO:0090150 54 0.027
retinal blood vessel morphogenesis GO:0061304 3 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
coagulation GO:0050817 78 0.027
innate immune response GO:0045087 157 0.027
cellular ion homeostasis GO:0006873 165 0.027
heart morphogenesis GO:0003007 178 0.027
organophosphate biosynthetic process GO:0090407 122 0.026
positive regulation of kinase activity GO:0033674 155 0.026
multicellular organism growth GO:0035264 161 0.026
regulation of intracellular protein transport GO:0033157 82 0.026
positive regulation of protein kinase activity GO:0045860 144 0.026
calcium ion transport GO:0006816 159 0.026
cytoplasmic transport GO:0016482 234 0.026
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.025
protein localization to membrane GO:0072657 108 0.025
Mouse
regulation of secretion GO:0051046 274 0.025
stress activated protein kinase signaling cascade GO:0031098 81 0.025
endothelial cell migration GO:0043542 44 0.025
connective tissue development GO:0061448 179 0.025
cellular response to hormone stimulus GO:0032870 150 0.025
cation homeostasis GO:0055080 212 0.025
divalent inorganic cation transport GO:0072511 178 0.025
purine containing compound metabolic process GO:0072521 311 0.025
termination of rna polymerase i transcription GO:0006363 2 0.025
negative regulation of phosphorylation GO:0042326 166 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
lateral line system development GO:0048925 1 0.024
acetylcholine transport GO:0015870 2 0.024
peptidyl tyrosine modification GO:0018212 145 0.024
oxidation reduction process GO:0055114 342 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
regulation of reproductive process GO:2000241 66 0.024
i kappab kinase nf kappab signaling GO:0007249 85 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
single fertilization GO:0007338 82 0.024
negative regulation of map kinase activity GO:0043407 34 0.024
positive regulation of homeostatic process GO:0032846 64 0.024
regulation of innate immune response GO:0045088 91 0.024
divalent metal ion transport GO:0070838 172 0.024
phagocytosis GO:0006909 66 0.024
cellular metal ion homeostasis GO:0006875 151 0.023
glomerular epithelium development GO:0072010 11 0.023
cell junction assembly GO:0034329 52 0.023
regulation of lipid metabolic process GO:0019216 118 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
response to transforming growth factor beta GO:0071559 88 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.023
ameboidal type cell migration GO:0001667 128 0.023
cardiocyte differentiation GO:0035051 87 0.023
peptidyl tyrosine phosphorylation GO:0018108 143 0.022
negative regulation of apoptotic signaling pathway GO:2001234 104 0.022
regulation of actin filament based process GO:0032970 99 0.022
morphogenesis of a branching epithelium GO:0061138 193 0.022
inflammatory response GO:0006954 244 0.022
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.022
regionalization GO:0003002 337 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
heterocycle catabolic process GO:0046700 280 0.022
nephron development GO:0072006 109 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
fertilization GO:0009566 127 0.022
leukocyte differentiation GO:0002521 342 0.022
glomerular epithelial cell development GO:0072310 6 0.022
apoptotic signaling pathway GO:0097190 306 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
sperm motility GO:0030317 47 0.022
ras protein signal transduction GO:0007265 77 0.021
response to extracellular stimulus GO:0009991 127 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
regulation of erk1 and erk2 cascade GO:0070372 71 0.021
epithelial cell morphogenesis GO:0003382 41 0.021
response to oxidative stress GO:0006979 123 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.021
dermatan sulfate proteoglycan metabolic process GO:0050655 1 0.021
regulation of protein kinase b signaling GO:0051896 56 0.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.021
morphogenesis of a branching structure GO:0001763 203 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.021
cardiac chamber development GO:0003205 108 0.021
telencephalon development GO:0021537 186 0.021
actomyosin structure organization GO:0031032 56 0.020
kidney vasculature development GO:0061440 15 0.020
cardiac muscle tissue development GO:0048738 130 0.020
response to acid chemical GO:0001101 111 0.020
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
cyclic nucleotide metabolic process GO:0009187 59 0.020
positive regulation of cytoplasmic transport GO:1903651 40 0.020
cell differentiation involved in kidney development GO:0061005 33 0.020
digestive tract morphogenesis GO:0048546 147 0.020
mesenchymal cell development GO:0014031 93 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.020
regulation of cell shape GO:0008360 39 0.020
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.020
mineralocorticoid biosynthetic process GO:0006705 1 0.020
regulation of defense response GO:0031347 233 0.020
response to monosaccharide GO:0034284 67 0.020
nucleoside catabolic process GO:0009164 206 0.020
stem cell differentiation GO:0048863 268 0.020
ribose phosphate biosynthetic process GO:0046390 59 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.019
cardiac muscle contraction GO:0060048 32 0.019
cellular response to steroid hormone stimulus GO:0071383 33 0.019
nucleoside phosphate biosynthetic process GO:1901293 79 0.019
regulation of cell projection organization GO:0031344 206 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
metanephric s shaped body morphogenesis GO:0072284 2 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
response to nutrient levels GO:0031667 109 0.019
regulation of blood circulation GO:1903522 93 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
cytosolic calcium ion homeostasis GO:0051480 70 0.019
sensory system development GO:0048880 3 0.019
epidermis development GO:0008544 187 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.018
regulation of protein catabolic process GO:0042176 108 0.018
cell cell junction assembly GO:0007043 27 0.018
protein localization to organelle GO:0033365 185 0.018
kidney development GO:0001822 213 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
regulation of multi organism process GO:0043900 111 0.018
regulation of nucleocytoplasmic transport GO:0046822 73 0.018
female gonad development GO:0008585 71 0.018
branching morphogenesis of an epithelial tube GO:0048754 159 0.018
amine metabolic process GO:0009308 45 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
muscle system process GO:0003012 141 0.018
cell chemotaxis GO:0060326 81 0.018
development of primary female sexual characteristics GO:0046545 73 0.018
multi multicellular organism process GO:0044706 109 0.018
Mouse
actin filament organization GO:0007015 113 0.017
negative regulation of mitotic cell cycle GO:0045930 58 0.017
peptidyl serine modification GO:0018209 83 0.017
cellular homeostasis GO:0019725 240 0.017
positive regulation of map kinase activity GO:0043406 84 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
epithelial cell proliferation GO:0050673 174 0.017
defense response to bacterium GO:0042742 119 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
response to metal ion GO:0010038 47 0.017
regulation of tissue remodeling GO:0034103 38 0.017
odontogenesis GO:0042476 78 0.017
regulation of anatomical structure size GO:0090066 178 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
regulation of hormone levels GO:0010817 211 0.016
anatomical structure arrangement GO:0048532 20 0.016
nucleotide catabolic process GO:0009166 217 0.016
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.016
leukocyte migration GO:0050900 124 0.016
lateral line nerve development GO:0048892 1 0.016
positive regulation of cell development GO:0010720 237 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
protein export from nucleus GO:0006611 20 0.016
neuron death GO:0070997 154 0.016
myotube differentiation GO:0014902 105 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
mesonephros development GO:0001823 97 0.016
proteoglycan metabolic process GO:0006029 38 0.016
response to steroid hormone GO:0048545 56 0.016
camp metabolic process GO:0046058 40 0.016
gonad development GO:0008406 141 0.016
locomotory behavior GO:0007626 195 0.016
cell cycle g1 s phase transition GO:0044843 57 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
lamellipodium organization GO:0097581 29 0.015
gtp metabolic process GO:0046039 144 0.015
regulation of heart contraction GO:0008016 77 0.015
nuclear export GO:0051168 34 0.015
regulation of striated muscle cell differentiation GO:0051153 81 0.015
protein kinase b signaling GO:0043491 74 0.015
positive regulation of transferase activity GO:0051347 167 0.015
leukocyte proliferation GO:0070661 172 0.015
small molecule biosynthetic process GO:0044283 132 0.015
regulation of epidermis development GO:0045682 33 0.015
mitochondrion organization GO:0007005 134 0.015
macromolecule catabolic process GO:0009057 281 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
endocytosis GO:0006897 168 0.015
adrenal cortex formation GO:0035802 2 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.015
cellular response to oxidative stress GO:0034599 76 0.015
neuron projection guidance GO:0097485 141 0.015
organelle fission GO:0048285 170 0.014
negative regulation of endothelial cell proliferation GO:0001937 8 0.014
axonogenesis GO:0007409 274 0.014
glucose homeostasis GO:0042593 128 0.014
actin filament based movement GO:0030048 23 0.014
c21 steroid hormone biosynthetic process GO:0006700 3 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.014
male sex differentiation GO:0046661 109 0.014
regulation of protein transport GO:0051223 163 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
metanephric nephron development GO:0072210 34 0.014
epithelial cell differentiation involved in kidney development GO:0035850 23 0.014
negative regulation of neuron differentiation GO:0045665 101 0.014
lipid biosynthetic process GO:0008610 179 0.014
nephron morphogenesis GO:0072028 69 0.014
mesenchymal cell differentiation GO:0048762 107 0.014
gastrulation GO:0007369 116 0.014
cell matrix adhesion GO:0007160 68 0.014
Mouse
bone morphogenesis GO:0060349 78 0.014
regulation of camp metabolic process GO:0030814 30 0.014
membrane raft assembly GO:0001765 3 0.014
Mouse
production of molecular mediator of immune response GO:0002440 103 0.014
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
aldosterone metabolic process GO:0032341 2 0.014
metanephric comma shaped body morphogenesis GO:0072278 1 0.014
kidney epithelium development GO:0072073 121 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
mesoderm development GO:0007498 100 0.014
response to light stimulus GO:0009416 135 0.014
negative regulation of multi organism process GO:0043901 68 0.014
regulation of blood pressure GO:0008217 93 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
muscle contraction GO:0006936 101 0.014
muscle fiber development GO:0048747 76 0.014
regulation of response to wounding GO:1903034 189 0.014
female sex differentiation GO:0046660 84 0.014
negative regulation of mapk cascade GO:0043409 65 0.014
carbohydrate homeostasis GO:0033500 128 0.013
sodium ion export GO:0071436 2 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
learning or memory GO:0007611 148 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
sensory perception GO:0007600 245 0.013
mitotic cytokinesis GO:0000281 4 0.013
glomerular mesangial cell proliferation GO:0072110 3 0.013
response to estrogen GO:0043627 24 0.013
integrin mediated signaling pathway GO:0007229 27 0.013
Mouse
establishment of protein localization to organelle GO:0072594 118 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.013
negative regulation of reactive oxygen species biosynthetic process GO:1903427 0 0.013
immune effector process GO:0002252 321 0.013
Mouse
adrenal cortex development GO:0035801 2 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.013
compound eye development GO:0048749 1 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
striated muscle contraction GO:0006941 45 0.013
actin mediated cell contraction GO:0070252 15 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
positive regulation of peptidase activity GO:0010952 49 0.013
forebrain cell migration GO:0021885 58 0.013
organelle assembly GO:0070925 177 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
negative regulation of ovulation GO:0060280 1 0.013
heart contraction GO:0060047 93 0.013
regulation of leukocyte apoptotic process GO:2000106 56 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
regulation of neuron death GO:1901214 134 0.013
mesenchyme development GO:0060485 152 0.012
negative regulation of protein modification process GO:0031400 163 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
glycerolipid metabolic process GO:0046486 122 0.012
development of primary sexual characteristics GO:0045137 143 0.012
negative regulation of immune system process GO:0002683 209 0.012
carbohydrate metabolic process GO:0005975 230 0.012
endochondral bone morphogenesis GO:0060350 50 0.012
regulation of cell migration GO:0030334 219 0.012
epithelium migration GO:0090132 63 0.012
negative regulation of hormone biosynthetic process GO:0032353 4 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
nitrogen compound transport GO:0071705 271 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
nucleoside metabolic process GO:0009116 246 0.012
meiotic cell cycle GO:0051321 122 0.012
acetate ester transport GO:1901374 2 0.012
myosin filament assembly GO:0031034 2 0.012
myeloid cell differentiation GO:0030099 233 0.012
inner ear morphogenesis GO:0042472 101 0.012
actin filament polymerization GO:0030041 44 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
positive regulation of vasoconstriction GO:0045907 4 0.012
muscle cell development GO:0055001 133 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
response to lipopolysaccharide GO:0032496 128 0.012
lipid transport GO:0006869 98 0.012
regulation of biomineral tissue development GO:0070167 33 0.012
tissue migration GO:0090130 68 0.012
inter male aggressive behavior GO:0002121 3 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
negative regulation of cell adhesion GO:0007162 45 0.012
cellular protein complex assembly GO:0043623 116 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
cellular response to lipid GO:0071396 145 0.012
sequestering of calcium ion GO:0051208 18 0.012
protein import GO:0017038 101 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
regulation of blood vessel remodeling GO:0060312 3 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
cartilage development GO:0051216 140 0.011

Pmp22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.297
Human
disease of anatomical entity DOID:7 0 0.297
Human
charcot marie tooth disease DOID:10595 0 0.297
Human
nervous system disease DOID:863 0 0.297
Human
neuropathy DOID:870 0 0.297
Human
sensory system disease DOID:0050155 0 0.038
eye and adnexa disease DOID:1492 0 0.038
eye disease DOID:5614 0 0.038
retinal disease DOID:5679 0 0.027
retinal degeneration DOID:8466 0 0.027
immune system disease DOID:2914 0 0.021
Human
hematopoietic system disease DOID:74 0 0.021
musculoskeletal system disease DOID:17 0 0.017
bone development disease DOID:0080006 0 0.013
bone disease DOID:0080001 0 0.013
connective tissue disease DOID:65 0 0.013