Mus musculus

64 known processes

Pnpla2

patatin-like phospholipase domain containing 2

(Aliases: 0610039C21Rik,1110001C14Rik,Atgl,TTS-2.2)

Pnpla2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
acylglycerol catabolic process GO:0046464 11 1.000
cellular lipid catabolic process GO:0044242 52 1.000
glycerolipid catabolic process GO:0046503 16 1.000
positive regulation of lipid catabolic process GO:0050996 6 1.000
triglyceride metabolic process GO:0006641 51 1.000
acylglycerol metabolic process GO:0006639 55 0.999
regulation of sequestering of triglyceride GO:0010889 6 0.999
regulation of triglyceride metabolic process GO:0090207 17 0.999
regulation of fatty acid oxidation GO:0046320 10 0.998
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.998
neutral lipid catabolic process GO:0046461 11 0.998
negative regulation of serotonin secretion GO:0014063 2 0.998
positive regulation of triglyceride metabolic process GO:0090208 9 0.998
regulation of lipoprotein lipase activity GO:0051004 4 0.997
lipid catabolic process GO:0016042 69 0.997
operant conditioning GO:0035106 2 0.996
brown fat cell differentiation GO:0050873 36 0.996
positive regulation of lipoprotein lipase activity GO:0051006 3 0.996
regulation of fatty acid metabolic process GO:0019217 28 0.996
regulation of cellular ketone metabolic process GO:0010565 66 0.995
neutral lipid metabolic process GO:0006638 57 0.995
regulation of triglyceride catabolic process GO:0010896 5 0.994
monocarboxylic acid metabolic process GO:0032787 191 0.989
positive regulation of cellular catabolic process GO:0031331 148 0.988
fatty acid metabolic process GO:0006631 121 0.988
regulation of lipid catabolic process GO:0050994 15 0.986
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.986
negative regulation of lipid metabolic process GO:0045833 30 0.986
cellular ketone metabolic process GO:0042180 84 0.985
cellular lipid metabolic process GO:0044255 323 0.982
regulation of cellular catabolic process GO:0031329 242 0.982
fatty acid catabolic process GO:0009062 25 0.978
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.975
regulation of lipid storage GO:0010883 20 0.973
lipid oxidation GO:0034440 29 0.971
positive regulation of triglyceride lipase activity GO:0061365 3 0.966
positive regulation of glycolytic process GO:0045821 4 0.964
glycolytic process GO:0006096 20 0.964
g protein coupled receptor internalization GO:0002031 3 0.963
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.961
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 8 0.959
negative regulation of lipid storage GO:0010888 6 0.958
sequestering of triglyceride GO:0030730 6 0.957
glycerolipid metabolic process GO:0046486 122 0.955
positive regulation of lipid metabolic process GO:0045834 40 0.951
regulation of the force of heart contraction GO:0002026 17 0.951
regulation of the force of heart contraction by chemical signal GO:0003057 5 0.949
histamine induced gastric acid secretion GO:0001697 1 0.948
lipid storage GO:0019915 36 0.948
regulation of lipid metabolic process GO:0019216 118 0.947
positive regulation of fatty acid oxidation GO:0046321 4 0.947
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.947
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.943
acylglycerol biosynthetic process GO:0046463 18 0.937
carbohydrate metabolic process GO:0005975 230 0.937
organic acid catabolic process GO:0016054 51 0.937
generation of precursor metabolites and energy GO:0006091 103 0.935
glycerolipid biosynthetic process GO:0045017 50 0.934
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.933
fatty acid oxidation GO:0019395 28 0.927
cellular response to temperature stimulus GO:0071502 2 0.924
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.920
ras protein signal transduction GO:0007265 77 0.920
small gtpase mediated signal transduction GO:0007264 97 0.914
regulation of carbohydrate metabolic process GO:0006109 75 0.914
lipid biosynthetic process GO:0008610 179 0.913
monocarboxylic acid catabolic process GO:0072329 27 0.911
carboxylic acid catabolic process GO:0046395 51 0.903
regulation of hydrolase activity GO:0051336 246 0.901
oxidation reduction process GO:0055114 342 0.900
pyruvate metabolic process GO:0006090 28 0.895
habituation GO:0046959 3 0.890
activation of adenylate cyclase activity GO:0007190 4 0.889
small molecule catabolic process GO:0044282 71 0.888
serotonin receptor signaling pathway GO:0007210 8 0.883
carbohydrate catabolic process GO:0016052 32 0.882
regulation of cellular amino acid metabolic process GO:0006521 5 0.876
fatty acid beta oxidation GO:0006635 16 0.871
response to peptide GO:1901652 136 0.869
gastrin induced gastric acid secretion GO:0001698 1 0.867
sensitization GO:0046960 2 0.863
organophosphate biosynthetic process GO:0090407 122 0.856
triglyceride biosynthetic process GO:0019432 17 0.851
glucose homeostasis GO:0042593 128 0.850
positive regulation of triglyceride catabolic process GO:0010898 3 0.848
positive regulation of cellular amine metabolic process GO:0033240 5 0.845
positive regulation of camp metabolic process GO:0030816 19 0.841
response to ammonium ion GO:0060359 21 0.832
glucose transport GO:0015758 56 0.809
phospholipase c activating dopamine receptor signaling pathway GO:0060158 5 0.805
cellular carbohydrate metabolic process GO:0044262 119 0.803
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.795
positive regulation of mapk cascade GO:0043410 170 0.793
negative regulation of muscle contraction GO:0045932 12 0.792
response to peptide hormone GO:0043434 127 0.786
regulation of appetite GO:0032098 12 0.777
response to alkaloid GO:0043279 34 0.774
vasodilation GO:0042311 28 0.758
regulation of kinase activity GO:0043549 249 0.757
temperature homeostasis GO:0001659 26 0.753
negative regulation of systemic arterial blood pressure GO:0003085 15 0.749
amine metabolic process GO:0009308 45 0.747
positive regulation of ras gtpase activity GO:0032320 65 0.747
regulation of cellular amine metabolic process GO:0033238 20 0.746
neutral lipid biosynthetic process GO:0046460 18 0.746
regulation of fat cell differentiation GO:0045598 81 0.743
lipid modification GO:0030258 65 0.741
cellular amine metabolic process GO:0044106 44 0.739
response to amphetamine GO:0001975 16 0.736
cellular response to hormone stimulus GO:0032870 150 0.735
glucose import GO:0046323 32 0.735
regulation of serotonin secretion GO:0014062 3 0.735
peptidyl amino acid modification GO:0018193 336 0.728
long term synaptic depression GO:0060292 13 0.728
positive regulation of fat cell differentiation GO:0045600 32 0.725
regulation of carbohydrate catabolic process GO:0043470 12 0.708
cellular chemical homeostasis GO:0055082 215 0.690
heat generation GO:0031649 13 0.688
regulation of adenylate cyclase activity GO:0045761 10 0.685
cyclic purine nucleotide metabolic process GO:0052652 43 0.684
adrenergic receptor signaling pathway GO:0071875 13 0.684
peptidyl tyrosine modification GO:0018212 145 0.682
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.681
corticotropin releasing hormone secretion GO:0043396 2 0.678
conditioned taste aversion GO:0001661 4 0.671
organic hydroxy compound transport GO:0015850 93 0.669
smooth muscle contraction GO:0006939 44 0.667
cellular response to peptide GO:1901653 92 0.666
regulation of generation of precursor metabolites and energy GO:0043467 38 0.665
nucleotide biosynthetic process GO:0009165 78 0.662
hormone secretion GO:0046879 128 0.659
regulation of glycolytic process GO:0006110 10 0.651
ribose phosphate biosynthetic process GO:0046390 59 0.651
response to nutrient levels GO:0031667 109 0.643
cholesterol storage GO:0010878 4 0.640
nucleotide metabolic process GO:0009117 332 0.638
negative regulation of fatty acid oxidation GO:0046322 5 0.635
negative regulation of fatty acid metabolic process GO:0045922 10 0.631
multicellular organism growth GO:0035264 161 0.630
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 6 0.629
diacylglycerol metabolic process GO:0046339 6 0.629
positive regulation of hydrolase activity GO:0051345 148 0.626
regulation of lipid biosynthetic process GO:0046890 54 0.625
monosaccharide metabolic process GO:0005996 106 0.616
positive regulation of carbohydrate metabolic process GO:0045913 30 0.615
positive regulation of kinase activity GO:0033674 155 0.610
purine nucleotide biosynthetic process GO:0006164 65 0.608
purine ribonucleotide biosynthetic process GO:0009152 59 0.605
multicellular organismal metabolic process GO:0044236 28 0.603
fat cell differentiation GO:0045444 160 0.602
regulation of hormone levels GO:0010817 211 0.601
striated muscle hypertrophy GO:0014897 24 0.598
response to insulin GO:0032868 100 0.595
astrocyte development GO:0014002 12 0.592
negative regulation of lipid catabolic process GO:0050995 6 0.592
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.592
response to cold GO:0009409 19 0.585
purine nucleoside triphosphate catabolic process GO:0009146 203 0.585
purine containing compound biosynthetic process GO:0072522 70 0.580
nucleoside phosphate biosynthetic process GO:1901293 79 0.574
protein secretion GO:0009306 111 0.571
positive regulation of fatty acid metabolic process GO:0045923 8 0.565
negative regulation of secretion by cell GO:1903531 54 0.563
negative regulation of phosphorus metabolic process GO:0010563 184 0.561
telencephalon cell migration GO:0022029 55 0.560
catecholamine metabolic process GO:0006584 30 0.559
cellular homeostasis GO:0019725 240 0.558
regulation of defense response GO:0031347 233 0.558
mitochondrion organization GO:0007005 134 0.557
acylglycerol homeostasis GO:0055090 16 0.551
positive regulation of endothelial cell proliferation GO:0001938 17 0.550
action potential GO:0001508 78 0.544
regulation of peptide secretion GO:0002791 77 0.539
single organism nuclear import GO:1902593 95 0.536
response to organonitrogen compound GO:0010243 246 0.536
regulation of nucleoside metabolic process GO:0009118 130 0.533
epithelial cell proliferation GO:0050673 174 0.533
heterocycle catabolic process GO:0046700 280 0.529
purine ribonucleotide metabolic process GO:0009150 290 0.529
cellular carbohydrate catabolic process GO:0044275 15 0.522
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.522
triglyceride homeostasis GO:0070328 15 0.522
regulation of lyase activity GO:0051339 13 0.521
regulation of blood pressure GO:0008217 93 0.514
carbohydrate transport GO:0008643 62 0.513
camp biosynthetic process GO:0006171 31 0.513
negative regulation of triglyceride metabolic process GO:0090209 4 0.511
synaptic transmission GO:0007268 329 0.511
serotonin transport GO:0006837 11 0.509
cytoplasmic transport GO:0016482 234 0.509
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.508
response to temperature stimulus GO:0009266 55 0.506
protein localization to organelle GO:0033365 185 0.503
peptidyl tyrosine phosphorylation GO:0018108 143 0.500
camp metabolic process GO:0046058 40 0.499
ribonucleotide biosynthetic process GO:0009260 59 0.496
cellular amino acid metabolic process GO:0006520 103 0.494
regulation of glucose metabolic process GO:0010906 60 0.493
positive regulation of transferase activity GO:0051347 167 0.492
regulation of membrane potential GO:0042391 192 0.489
lipid localization GO:0010876 126 0.488
endothelial cell proliferation GO:0001935 27 0.487
nuclear transport GO:0051169 139 0.485
protein localization to nucleus GO:0034504 121 0.484
monoamine transport GO:0015844 33 0.481
regulation of ras gtpase activity GO:0032318 88 0.479
regulation of lipase activity GO:0060191 15 0.478
ameboidal type cell migration GO:0001667 128 0.477
g protein coupled receptor signaling pathway GO:0007186 243 0.474
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.474
regulation of smooth muscle contraction GO:0006940 22 0.471
energy reserve metabolic process GO:0006112 39 0.469
regulation of nucleotide catabolic process GO:0030811 122 0.463
toxin transport GO:1901998 38 0.462
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.462
energy derivation by oxidation of organic compounds GO:0015980 77 0.460
peptide secretion GO:0002790 114 0.460
maintenance of location GO:0051235 89 0.459
peptide transport GO:0015833 133 0.459
glycosyl compound catabolic process GO:1901658 206 0.459
regulation of camp metabolic process GO:0030814 30 0.459
response to cocaine GO:0042220 14 0.457
multicellular organismal homeostasis GO:0048871 164 0.455
camp mediated signaling GO:0019933 15 0.452
regulation of fatty acid beta oxidation GO:0031998 1 0.450
mapk cascade GO:0000165 281 0.446
neural crest cell migration GO:0001755 32 0.446
negative regulation of blood pressure GO:0045776 22 0.441
triglyceride catabolic process GO:0019433 9 0.441
regulation of synaptic transmission glutamatergic GO:0051966 19 0.440
purine nucleoside metabolic process GO:0042278 241 0.440
positive regulation of cell migration GO:0030335 109 0.436
serotonin metabolic process GO:0042428 8 0.433
regulation of triglyceride biosynthetic process GO:0010866 10 0.433
stem cell development GO:0048864 219 0.432
lipid transport GO:0006869 98 0.431
response to extracellular stimulus GO:0009991 127 0.430
regulation of system process GO:0044057 200 0.428
regulation of protein transport GO:0051223 163 0.428
negative regulation of molecular function GO:0044092 258 0.427
purine nucleotide catabolic process GO:0006195 211 0.426
cardiac muscle hypertrophy GO:0003300 23 0.426
sterol metabolic process GO:0016125 58 0.425
regulation of mapk cascade GO:0043408 248 0.421
regulation of cell migration GO:0030334 219 0.421
positive regulation of protein phosphorylation GO:0001934 242 0.417
monosaccharide transport GO:0015749 58 0.416
negative regulation of defense response GO:0031348 77 0.416
positive regulation of cell division GO:0051781 31 0.413
carbohydrate homeostasis GO:0033500 128 0.412
positive regulation of protein modification process GO:0031401 299 0.412
ribonucleoside catabolic process GO:0042454 206 0.410
regulation of camp biosynthetic process GO:0030817 25 0.407
lipid homeostasis GO:0055088 63 0.406
Fly
regulation of biomineral tissue development GO:0070167 33 0.403
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.402
positive regulation of sequestering of triglyceride GO:0010890 4 0.399
long term synaptic potentiation GO:0060291 25 0.399
peristalsis GO:0030432 8 0.398
regulation of transferase activity GO:0051338 263 0.397
organic cyclic compound catabolic process GO:1901361 295 0.394
ribonucleoside triphosphate catabolic process GO:0009203 199 0.393
glucose metabolic process GO:0006006 92 0.392
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 12 0.392
striatum development GO:0021756 14 0.388
nucleobase containing small molecule metabolic process GO:0055086 352 0.387
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.387
regulation of purine nucleotide catabolic process GO:0033121 122 0.382
positive regulation of gtp catabolic process GO:0033126 85 0.382
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.378
mating behavior GO:0007617 20 0.375
aromatic compound catabolic process GO:0019439 286 0.374
positive regulation of lipid biosynthetic process GO:0046889 18 0.373
guanosine containing compound catabolic process GO:1901069 144 0.373
ribonucleoside metabolic process GO:0009119 245 0.371
response to organic cyclic compound GO:0014070 198 0.371
inflammatory response GO:0006954 244 0.370
regulation of nitrogen cycle metabolic process GO:1903314 1 0.370
cyclic nucleotide mediated signaling GO:0019935 18 0.363
dopamine transport GO:0015872 15 0.362
heart process GO:0003015 94 0.360
behavioral response to cocaine GO:0048148 10 0.358
cyclic nucleotide biosynthetic process GO:0009190 44 0.357
positive regulation of camp biosynthetic process GO:0030819 19 0.357
neuronal action potential GO:0019228 54 0.355
regulation of insulin receptor signaling pathway GO:0046626 21 0.351
guanosine containing compound metabolic process GO:1901068 144 0.350
protein import into nucleus GO:0006606 95 0.344
amide transport GO:0042886 138 0.343
insulin receptor signaling pathway GO:0008286 49 0.342
parental behavior GO:0060746 11 0.341
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.336
epithelial cell morphogenesis GO:0003382 41 0.333
digestion GO:0007586 40 0.333
neural crest cell development GO:0014032 48 0.331
regulation of ras protein signal transduction GO:0046578 114 0.330
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.325
purine nucleoside catabolic process GO:0006152 205 0.325
regulation of hormone secretion GO:0046883 88 0.323
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.322
glycogen metabolic process GO:0005977 32 0.321
negative regulation of purine nucleotide biosynthetic process GO:1900372 6 0.321
dopamine receptor signaling pathway GO:0007212 16 0.319
organonitrogen compound catabolic process GO:1901565 264 0.318
purine containing compound catabolic process GO:0072523 213 0.317
intestinal absorption GO:0050892 13 0.316
purine ribonucleoside catabolic process GO:0046130 205 0.314
negative regulation of phosphate metabolic process GO:0045936 184 0.313
ribonucleotide metabolic process GO:0009259 291 0.312
carbohydrate derivative biosynthetic process GO:1901137 183 0.312
positive regulation of gtpase activity GO:0043547 85 0.312
establishment of protein localization to organelle GO:0072594 118 0.311
multicellular organismal signaling GO:0035637 91 0.310
nucleoside metabolic process GO:0009116 246 0.308
forebrain generation of neurons GO:0021872 63 0.308
purine containing compound metabolic process GO:0072521 311 0.308
regulation of peptide hormone secretion GO:0090276 75 0.308
regulation of peptide transport GO:0090087 91 0.307
blood vessel morphogenesis GO:0048514 285 0.305
stem cell differentiation GO:0048863 268 0.303
regulation of cyclase activity GO:0031279 13 0.302
regulation of reactive oxygen species metabolic process GO:2000377 40 0.301
positive regulation of nucleoside metabolic process GO:0045979 91 0.300
regulation of synaptic plasticity GO:0048167 87 0.299
ribonucleotide catabolic process GO:0009261 208 0.299
associative learning GO:0008306 61 0.298
dopamine metabolic process GO:0042417 23 0.298
forebrain neuron development GO:0021884 30 0.295
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.295
cellular polysaccharide metabolic process GO:0044264 38 0.295
cellular response to organonitrogen compound GO:0071417 145 0.294
nucleocytoplasmic transport GO:0006913 139 0.293
intracellular protein transport GO:0006886 204 0.292
subpallium development GO:0021544 20 0.291
anatomical structure homeostasis GO:0060249 145 0.289
blood circulation GO:0008015 195 0.288
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.288
vascular process in circulatory system GO:0003018 62 0.286
positive regulation of fatty acid beta oxidation GO:0032000 1 0.285
cerebral cortex neuron differentiation GO:0021895 19 0.284
organic hydroxy compound metabolic process GO:1901615 203 0.282
regulation of muscle system process GO:0090257 80 0.282
digestive tract development GO:0048565 190 0.280
regulation of systemic arterial blood pressure GO:0003073 61 0.279
organonitrogen compound biosynthetic process GO:1901566 192 0.279
polysaccharide metabolic process GO:0005976 39 0.278
hexose transport GO:0008645 56 0.277
intracellular receptor signaling pathway GO:0030522 74 0.276
response to radiation GO:0009314 165 0.276
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.275
regulation of ossification GO:0030278 112 0.274
indole containing compound metabolic process GO:0042430 12 0.274
ossification GO:0001503 216 0.274
diet induced thermogenesis GO:0002024 7 0.274
negative regulation of smooth muscle contraction GO:0045986 10 0.274
regulation of catecholamine metabolic process GO:0042069 10 0.272
positive regulation of nucleotide metabolic process GO:0045981 114 0.272
gland development GO:0048732 330 0.271
cyclic nucleotide metabolic process GO:0009187 59 0.270
nucleotide catabolic process GO:0009166 217 0.269
nucleoside catabolic process GO:0009164 206 0.269
mesenchymal cell development GO:0014031 93 0.267
steroid metabolic process GO:0008202 119 0.267
protein localization to cytoskeleton GO:0044380 9 0.267
epithelial cell development GO:0002064 159 0.266
regulation of multicellular organismal metabolic process GO:0044246 14 0.265
regulation of gluconeogenesis GO:0006111 30 0.265
digestive system development GO:0055123 200 0.265
positive regulation of heart contraction GO:0045823 14 0.262
dentate gyrus development GO:0021542 14 0.262
phenol containing compound metabolic process GO:0018958 60 0.261
gtp metabolic process GO:0046039 144 0.257
regulation of endothelial cell proliferation GO:0001936 23 0.257
small molecule biosynthetic process GO:0044283 132 0.253
purine nucleotide metabolic process GO:0006163 302 0.253
ribose phosphate metabolic process GO:0019693 291 0.253
bone remodeling GO:0046849 53 0.253
adult behavior GO:0030534 135 0.252
mesenchymal cell differentiation GO:0048762 107 0.252
peptide hormone secretion GO:0030072 109 0.251
visual behavior GO:0007632 45 0.250
positive regulation of nucleotide catabolic process GO:0030813 88 0.250
pallium development GO:0021543 120 0.249
neural crest cell differentiation GO:0014033 54 0.249
heart contraction GO:0060047 93 0.246
feeding behavior GO:0007631 62 0.246
cholesterol metabolic process GO:0008203 56 0.244
ribonucleoside triphosphate metabolic process GO:0009199 220 0.243
hexose metabolic process GO:0019318 98 0.241
receptor internalization GO:0031623 16 0.237
positive regulation of apoptotic process GO:0043065 217 0.235
cellular response to insulin stimulus GO:0032869 78 0.235
positive regulation of camp mediated signaling GO:0043950 3 0.233
muscle contraction GO:0006936 101 0.232
regulation of nucleotide biosynthetic process GO:0030808 34 0.230
purine nucleoside triphosphate metabolic process GO:0009144 226 0.229
regulation of metal ion transport GO:0010959 106 0.227
response to amine GO:0014075 16 0.227
regulation of dopamine metabolic process GO:0042053 10 0.227
positive regulation of behavior GO:0048520 40 0.226
purine ribonucleotide catabolic process GO:0009154 208 0.225
regulation of sodium ion transport GO:0002028 29 0.224
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.224
negative regulation of secretion GO:0051048 61 0.224
negative regulation of growth GO:0045926 99 0.222
central nervous system neuron development GO:0021954 67 0.221
negative regulation of map kinase activity GO:0043407 34 0.219
nucleoside phosphate metabolic process GO:0006753 338 0.218
cellular ion homeostasis GO:0006873 165 0.216
sodium ion transport GO:0006814 73 0.215
nuclear import GO:0051170 95 0.215
striated muscle contraction GO:0006941 45 0.215
negative regulation of neuron apoptotic process GO:0043524 92 0.214
mammary gland epithelium development GO:0061180 65 0.212
nucleoside triphosphate metabolic process GO:0009141 230 0.212
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.212
grooming behavior GO:0007625 16 0.211
synaptic transmission glutamatergic GO:0035249 36 0.208
regulation of secretion by cell GO:1903530 249 0.206
protein import GO:0017038 101 0.206
forebrain neuron differentiation GO:0021879 52 0.206
positive regulation of secretion by cell GO:1903532 114 0.205
negative regulation of protein phosphorylation GO:0001933 126 0.203
regulation of nucleotide metabolic process GO:0006140 169 0.203
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.201
nitrogen compound transport GO:0071705 271 0.201
regulation of gtp catabolic process GO:0033124 113 0.200
regulation of protein secretion GO:0050708 82 0.199
coagulation GO:0050817 78 0.198
regulation of cell motility GO:2000145 236 0.196
second messenger mediated signaling GO:0019932 73 0.196
regulation of blood vessel size GO:0050880 56 0.196
fear response GO:0042596 33 0.196
multi organism reproductive behavior GO:0044705 29 0.195
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.195
cellular amide metabolic process GO:0043603 58 0.194
regulation of steroid biosynthetic process GO:0050810 26 0.194
circulatory system process GO:0003013 197 0.193
nucleoside triphosphate catabolic process GO:0009143 205 0.193
positive regulation of cell death GO:0010942 224 0.193
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.192
forebrain cell migration GO:0021885 58 0.192
glycosyl compound metabolic process GO:1901657 246 0.191
myeloid cell differentiation GO:0030099 233 0.190
regulation of plasma lipoprotein particle levels GO:0097006 23 0.189
positive regulation of protein transport GO:0051222 93 0.187
regulation of establishment of protein localization GO:0070201 181 0.185
cytokine production GO:0001816 319 0.185
catecholamine transport GO:0051937 21 0.184
regulation of cell division GO:0051302 76 0.184
carbohydrate biosynthetic process GO:0016051 74 0.184
gliogenesis GO:0042063 141 0.183
cellular response to growth factor stimulus GO:0071363 197 0.183
transmission of nerve impulse GO:0019226 76 0.181
cognition GO:0050890 149 0.180
autophagy GO:0006914 45 0.179
response to oxygen radical GO:0000305 16 0.179
gastric acid secretion GO:0001696 6 0.177
organophosphate catabolic process GO:0046434 232 0.176
substrate independent telencephalic tangential migration GO:0021826 8 0.176
bone mineralization GO:0030282 54 0.175
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.174
regulation of proteolysis GO:0030162 164 0.174
heart morphogenesis GO:0003007 178 0.174
multicellular organismal response to stress GO:0033555 62 0.173
gluconeogenesis GO:0006094 39 0.172
locomotory behavior GO:0007626 195 0.171
forebrain development GO:0030900 302 0.171
regulation of epithelial cell proliferation GO:0050678 141 0.169
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.168
visual learning GO:0008542 44 0.167
immune effector process GO:0002252 321 0.167
biomineral tissue development GO:0031214 64 0.166
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.166
lipid particle organization GO:0034389 7 0.165
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.165
sulfur compound metabolic process GO:0006790 100 0.165
cation homeostasis GO:0055080 212 0.164
regulation of protein localization GO:0032880 231 0.163
bone resorption GO:0045453 38 0.163
keratinocyte migration GO:0051546 3 0.163
cellular nitrogen compound catabolic process GO:0044270 280 0.163
hair cycle GO:0042633 90 0.163
regulation of cytokine production GO:0001817 266 0.163
positive regulation of cell motility GO:2000147 116 0.162
negative regulation of camp metabolic process GO:0030815 5 0.160
regulation of carbohydrate biosynthetic process GO:0043255 40 0.159
carbohydrate derivative catabolic process GO:1901136 231 0.159
regulation of tube size GO:0035150 57 0.158
central nervous system neuron differentiation GO:0021953 162 0.158
positive regulation of heart rate GO:0010460 10 0.158
organ regeneration GO:0031100 2 0.156
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.155

Pnpla2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.986
acquired metabolic disease DOID:0060158 0 0.820
nutrition disease DOID:374 0 0.417
overnutrition DOID:654 0 0.417
obesity DOID:9970 0 0.301
inherited metabolic disorder DOID:655 0 0.203