Mus musculus

0 known processes

Pole

polymerase (DNA directed), epsilon

Pole biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna recombination GO:0006310 92 0.727
Yeast
dna metabolic process GO:0006259 303 0.706
Human Yeast
dna repair GO:0006281 107 0.620
Human Yeast
nuclear division GO:0000280 158 0.525
Yeast
regulation of circadian sleep wake cycle GO:0042749 3 0.343
dna endoreduplication GO:0042023 4 0.311
dna dependent dna replication GO:0006261 24 0.309
Yeast
meiotic nuclear division GO:0007126 115 0.293
double strand break repair GO:0006302 48 0.290
Yeast
double strand break repair via homologous recombination GO:0000724 21 0.257
dna replication GO:0006260 52 0.254
Human Yeast
organelle fission GO:0048285 170 0.243
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.240
meiotic cell cycle process GO:1903046 77 0.235
recombinational repair GO:0000725 21 0.233
regulation of mitotic cell cycle phase transition GO:1901990 73 0.223
Yeast
mitotic cell cycle process GO:1903047 159 0.202
Human Yeast
sister chromatid cohesion GO:0007062 12 0.185
Yeast
mitotic cell cycle GO:0000278 195 0.171
Human Yeast
negative regulation of cell cycle phase transition GO:1901988 48 0.160
Yeast
reciprocal dna recombination GO:0035825 16 0.154
response to light stimulus GO:0009416 135 0.149
endocytosis GO:0006897 168 0.143
organic cyclic compound catabolic process GO:1901361 295 0.142
Yeast
nuclear dna replication GO:0033260 3 0.141
nucleobase containing small molecule metabolic process GO:0055086 352 0.118
regulation of hydrolase activity GO:0051336 246 0.117
meiotic cell cycle GO:0051321 122 0.116
regulation of cell cycle process GO:0010564 160 0.111
Yeast
chromosome organization involved in meiosis GO:0070192 39 0.109
cellular response to radiation GO:0071478 28 0.105
cellular response to dna damage stimulus GO:0006974 207 0.103
Human Yeast
nucleoside monophosphate metabolic process GO:0009123 85 0.100
nucleotide metabolic process GO:0009117 332 0.096
dna unwinding involved in dna replication GO:0006268 5 0.096
mitotic sister chromatid cohesion GO:0007064 1 0.088
Yeast
cellular amino acid metabolic process GO:0006520 103 0.088
cell cycle checkpoint GO:0000075 47 0.084
Yeast
microtubule cytoskeleton organization GO:0000226 157 0.082
cellular response to cytokine stimulus GO:0071345 189 0.068
regulation of chromosome segregation GO:0051983 21 0.068
inner cell mass cell proliferation GO:0001833 15 0.067
purine containing compound metabolic process GO:0072521 311 0.066
purine ribonucleoside metabolic process GO:0046128 241 0.064
sister chromatid segregation GO:0000819 20 0.063
Yeast
regulation of transcription by chromatin organization GO:0034401 0 0.063
meiosis ii GO:0007135 7 0.062
nucleoside metabolic process GO:0009116 246 0.062
organophosphate catabolic process GO:0046434 232 0.061
response to radiation GO:0009314 165 0.054
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.054
regulation of cell cycle phase transition GO:1901987 77 0.053
Yeast
organonitrogen compound catabolic process GO:1901565 264 0.051
purine ribonucleotide metabolic process GO:0009150 290 0.051
ribonucleotide metabolic process GO:0009259 291 0.049
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.049
purine nucleoside catabolic process GO:0006152 205 0.048
aromatic compound catabolic process GO:0019439 286 0.048
Yeast
meiotic sister chromatid segregation GO:0045144 6 0.045
cell division GO:0051301 120 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.042
regulation of organelle organization GO:0033043 289 0.042
negative regulation of cell proliferation GO:0008285 296 0.041
negative regulation of mitotic cell cycle GO:0045930 58 0.041
Yeast
purine containing compound catabolic process GO:0072523 213 0.038
regulation of chromosome organization GO:0033044 83 0.038
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
regulation of cell cycle GO:0051726 281 0.037
Yeast
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.037
camera type eye development GO:0043010 266 0.036
positive regulation of cellular catabolic process GO:0031331 148 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
atp catabolic process GO:0006200 55 0.036
heterocycle catabolic process GO:0046700 280 0.035
Yeast
nucleotide excision repair GO:0006289 13 0.035
Human Yeast
epithelial tube morphogenesis GO:0060562 303 0.035
cellular ketone metabolic process GO:0042180 84 0.035
multicellular organismal homeostasis GO:0048871 164 0.035
ribonucleoside triphosphate catabolic process GO:0009203 199 0.035
dna damage checkpoint GO:0000077 26 0.035
Yeast
oxidation reduction process GO:0055114 342 0.034
amine metabolic process GO:0009308 45 0.034
negative regulation of chromatin silencing GO:0031936 1 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
regulation of mitotic cell cycle GO:0007346 126 0.033
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
dna integrity checkpoint GO:0031570 28 0.032
Yeast
lateral inhibition GO:0046331 1 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.032
maintenance of location GO:0051235 89 0.032
glycosyl compound catabolic process GO:1901658 206 0.032
rhythmic process GO:0048511 174 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
positive regulation of mitotic cell cycle GO:0045931 41 0.031
negative regulation of molecular function GO:0044092 258 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
Yeast
male gamete generation GO:0048232 285 0.030
microtubule based process GO:0007017 236 0.030
purine nucleoside metabolic process GO:0042278 241 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
nucleoside triphosphate catabolic process GO:0009143 205 0.029
ribose phosphate metabolic process GO:0019693 291 0.028
locomotory behavior GO:0007626 195 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
lung development GO:0030324 164 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
nucleoside monophosphate catabolic process GO:0009125 59 0.025
negative regulation of cell cycle process GO:0010948 69 0.025
Yeast
nucleoside phosphate metabolic process GO:0006753 338 0.025
hatching GO:0035188 4 0.024
negative regulation of hydrolase activity GO:0051346 71 0.024
leukocyte activation involved in immune response GO:0002366 126 0.024
nucleoside catabolic process GO:0009164 206 0.024
branching morphogenesis of an epithelial tube GO:0048754 159 0.024
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.024
peptide transport GO:0015833 133 0.024
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.024
blastocyst growth GO:0001832 23 0.023
circadian temperature homeostasis GO:0060086 2 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
organism emergence from protective structure GO:0071684 4 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
negative regulation of organelle organization GO:0010639 90 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
Yeast
regulation of circadian rhythm GO:0042752 58 0.022
receptor mediated endocytosis GO:0006898 51 0.022
copulation GO:0007620 7 0.022
macromolecule catabolic process GO:0009057 281 0.022
Yeast
protein catabolic process GO:0030163 221 0.022
gland development GO:0048732 330 0.022
circadian rhythm GO:0007623 114 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
morphogenesis of a branching structure GO:0001763 203 0.021
nucleotide catabolic process GO:0009166 217 0.021
dna geometric change GO:0032392 7 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
regulation of cellular catabolic process GO:0031329 242 0.019
regulation of cellular response to stress GO:0080135 159 0.019
cell adhesion GO:0007155 329 0.019
atp metabolic process GO:0046034 75 0.019
regulation of binding GO:0051098 111 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
locomotor rhythm GO:0045475 8 0.019
negative regulation of protein processing GO:0010955 79 0.019
nitrogen compound transport GO:0071705 271 0.019
cellular amine metabolic process GO:0044106 44 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 1 0.018
gene silencing GO:0016458 38 0.018
Yeast
ion transmembrane transport GO:0034220 361 0.018
protein maturation GO:0051604 176 0.018
microtubule organizing center organization GO:0031023 28 0.018
centrosome cycle GO:0007098 23 0.018
apoptotic signaling pathway GO:0097190 306 0.018
membrane organization GO:0061024 245 0.018
dna duplex unwinding GO:0032508 7 0.018
reciprocal meiotic recombination GO:0007131 16 0.018
histone h3 k9 trimethylation GO:0036124 6 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
folic acid containing compound metabolic process GO:0006760 3 0.017
response to organonitrogen compound GO:0010243 246 0.017
rna catabolic process GO:0006401 29 0.017
response to extracellular stimulus GO:0009991 127 0.017
cellular response to abiotic stimulus GO:0071214 56 0.017
positive regulation of cell cycle phase transition GO:1901989 17 0.017
t cell activation GO:0042110 289 0.017
response to organic cyclic compound GO:0014070 198 0.017
regulation of proteolysis GO:0030162 164 0.016
b cell activation GO:0042113 161 0.016
methylation GO:0032259 134 0.016
peptidyl amino acid modification GO:0018193 336 0.016
immune effector process GO:0002252 321 0.016
regulation of cell division GO:0051302 76 0.016
negative regulation of cellular catabolic process GO:0031330 47 0.016
double strand break repair via nonhomologous end joining GO:0006303 10 0.016
Yeast
respiratory tube development GO:0030323 167 0.016
male meiosis GO:0007140 37 0.016
endomembrane system organization GO:0010256 147 0.016
immunoglobulin production GO:0002377 73 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
development of primary sexual characteristics GO:0045137 143 0.016
Worm
protein modification by small protein conjugation GO:0032446 187 0.016
respiratory system development GO:0060541 190 0.016
meiotic sister chromatid cohesion GO:0051177 6 0.016
mitotic sister chromatid segregation GO:0000070 14 0.016
Yeast
negative regulation of protein modification process GO:0031400 163 0.016
cellularization GO:0007349 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
striated muscle myosin thick filament assembly GO:0071688 1 0.015
sensory organ morphogenesis GO:0090596 242 0.015
negative regulation of proteolysis GO:0045861 74 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
base excision repair GO:0006284 9 0.015
Human Yeast
negative regulation of cell development GO:0010721 169 0.014
regulation of secretion GO:0051046 274 0.014
regulation of cytokine production GO:0001817 266 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
regulation of hormone levels GO:0010817 211 0.014
asymmetric neuroblast division GO:0055059 1 0.014
regulation of sister chromatid cohesion GO:0007063 5 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
positive regulation of histone h3 k4 methylation GO:0051571 5 0.014
spermatogenesis GO:0007283 284 0.014
regulation of dna binding GO:0051101 39 0.014
anatomical structure homeostasis GO:0060249 145 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
transmembrane transport GO:0055085 412 0.014
cation transport GO:0006812 399 0.014
blastocyst development GO:0001824 80 0.014
regulation of dna dependent dna replication GO:0090329 8 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
pyrimidine nucleobase metabolic process GO:0006206 3 0.014
regulation of protein catabolic process GO:0042176 108 0.014
chromatin organization GO:0006325 206 0.013
Yeast
leukocyte proliferation GO:0070661 172 0.013
regulation of dna dependent dna replication initiation GO:0030174 3 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.013
Yeast
forebrain development GO:0030900 302 0.013
cell activation involved in immune response GO:0002263 126 0.013
blood vessel morphogenesis GO:0048514 285 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
response to inorganic substance GO:0010035 96 0.013
myosin filament assembly GO:0031034 2 0.013
negative regulation of dna binding GO:0043392 20 0.013
cellular protein catabolic process GO:0044257 155 0.013
lymphocyte proliferation GO:0046651 164 0.013
divalent metal ion transport GO:0070838 172 0.013
fatty acid metabolic process GO:0006631 121 0.013
regulation of protein localization GO:0032880 231 0.013
gonad development GO:0008406 141 0.013
Worm
organelle localization GO:0051640 179 0.013
positive regulation of chromosome segregation GO:0051984 4 0.013
negative regulation of gene silencing GO:0060969 2 0.013
protein ubiquitination GO:0016567 171 0.012
negative regulation of binding GO:0051100 39 0.012
organic anion transport GO:0015711 137 0.012
protein localization to chromosome centromeric region GO:0071459 1 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
amide transport GO:0042886 138 0.012
developmental maturation GO:0021700 193 0.012
intra s dna damage checkpoint GO:0031573 4 0.012
Yeast
attachment of spindle microtubules to kinetochore GO:0008608 4 0.012
signal transduction by p53 class mediator GO:0072331 51 0.012
cytokine production GO:0001816 319 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
rna dependent dna replication GO:0006278 3 0.012
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
peptide hormone secretion GO:0030072 109 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
regulation of cell motility GO:2000145 236 0.012
lymphocyte differentiation GO:0030098 242 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
regulation of microtubule cytoskeleton organization GO:0070507 37 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
homeostasis of number of cells GO:0048872 210 0.012
chromosome segregation GO:0007059 48 0.012
Yeast
regulation of secretion by cell GO:1903530 249 0.011
negative regulation of cell cycle GO:0045786 123 0.011
Yeast
regulation of nucleotide metabolic process GO:0006140 169 0.011
mating GO:0007618 27 0.011
regulation of cell migration GO:0030334 219 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
protein processing GO:0016485 163 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
regulation of microtubule based process GO:0032886 52 0.011
dna biosynthetic process GO:0071897 22 0.011
Human Yeast
cellular response to interleukin 4 GO:0071353 21 0.011
circulatory system process GO:0003013 197 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
meiosis i GO:0007127 60 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of homeostatic process GO:0032844 182 0.011
anion transport GO:0006820 177 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
response to nutrient levels GO:0031667 109 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of response to wounding GO:1903034 189 0.010
purine nucleobase biosynthetic process GO:0009113 3 0.010
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.010
Yeast
rna interference GO:0016246 2 0.010
metaphase plate congression GO:0051310 2 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
blood circulation GO:0008015 195 0.010
tube closure GO:0060606 91 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
myosin filament organization GO:0031033 3 0.010
female meiosis chromosome segregation GO:0016321 1 0.010

Pole disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.734
Human
disease of cellular proliferation DOID:14566 0 0.734
Human
organ system cancer DOID:0050686 0 0.361
Human
gastrointestinal system cancer DOID:3119 0 0.076
Human
intestinal cancer DOID:10155 0 0.076
Human
thoracic cancer DOID:5093 0 0.072
large intestine cancer DOID:5672 0 0.054
Human
disease of metabolism DOID:0014667 0 0.039
inherited metabolic disorder DOID:655 0 0.039
immune system disease DOID:2914 0 0.027
disease of anatomical entity DOID:7 0 0.027
bone marrow disease DOID:4961 0 0.027
hematopoietic system disease DOID:74 0 0.027
nervous system disease DOID:863 0 0.026
breast cancer DOID:1612 0 0.025
carbohydrate metabolic disorder DOID:2978 0 0.011