Mus musculus

38 known processes

Polh

polymerase (DNA directed), eta (RAD 30 related)

(Aliases: XPV,RAD30A)

Polh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna recombination GO:0006310 92 0.406
translesion synthesis GO:0019985 1 0.370
dna repair GO:0006281 107 0.353
dna metabolic process GO:0006259 303 0.253
cellular response to dna damage stimulus GO:0006974 207 0.224
double strand break repair via homologous recombination GO:0000724 21 0.213
recombinational repair GO:0000725 21 0.198
double strand break repair GO:0006302 48 0.175
response to radiation GO:0009314 165 0.132
postreplication repair GO:0006301 5 0.111
cellular macromolecule catabolic process GO:0044265 206 0.109
regulation of double strand break repair via homologous recombination GO:0010569 2 0.081
dna biosynthetic process GO:0071897 22 0.074
response to light stimulus GO:0009416 135 0.071
regulation of dna recombination GO:0000018 34 0.070
mitotic cell cycle process GO:1903047 159 0.067
regulation of cellular response to stress GO:0080135 159 0.058
regulation of cell cycle process GO:0010564 160 0.056
cellular ketone metabolic process GO:0042180 84 0.050
regulation of cell cycle GO:0051726 281 0.048
cellular amine metabolic process GO:0044106 44 0.043
endocytosis GO:0006897 168 0.041
mitotic cell cycle GO:0000278 195 0.041
heterocycle catabolic process GO:0046700 280 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
amine metabolic process GO:0009308 45 0.038
protein catabolic process GO:0030163 221 0.036
microtubule based process GO:0007017 236 0.035
leukocyte differentiation GO:0002521 342 0.034
organic cyclic compound catabolic process GO:1901361 295 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.031
response to uv GO:0009411 44 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
regulation of organelle organization GO:0033043 289 0.030
cellular amino acid metabolic process GO:0006520 103 0.030
nuclear division GO:0000280 158 0.029
nucleotide metabolic process GO:0009117 332 0.029
regulation of response to dna damage stimulus GO:2001020 34 0.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
organelle fission GO:0048285 170 0.027
negative regulation of cell cycle GO:0045786 123 0.027
regulation of mitotic cell cycle phase transition GO:1901990 73 0.026
protein ubiquitination GO:0016567 171 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
aromatic compound catabolic process GO:0019439 286 0.026
purine containing compound metabolic process GO:0072521 311 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
negative regulation of cell cycle process GO:0010948 69 0.026
protein maturation GO:0051604 176 0.025
organelle assembly GO:0070925 177 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.025
cytoplasmic transport GO:0016482 234 0.024
methylation GO:0032259 134 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
transmembrane transport GO:0055085 412 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
response to organonitrogen compound GO:0010243 246 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.022
regulation of membrane potential GO:0042391 192 0.022
t cell activation GO:0042110 289 0.022
b cell activation GO:0042113 161 0.022
macromolecule catabolic process GO:0009057 281 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.021
regulation of mitotic cell cycle GO:0007346 126 0.021
regulation of cell cycle phase transition GO:1901987 77 0.021
regulation of proteolysis GO:0030162 164 0.021
compound eye development GO:0048749 1 0.021
peptidyl amino acid modification GO:0018193 336 0.021
apoptotic signaling pathway GO:0097190 306 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
regulation of chromosome organization GO:0033044 83 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
cytokine production GO:0001816 319 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
chromosome segregation GO:0007059 48 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
cellular chemical homeostasis GO:0055082 215 0.018
positive regulation of lymphocyte activation GO:0051251 140 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
divalent inorganic cation transport GO:0072511 178 0.018
positive regulation of protein modification process GO:0031401 299 0.018
endomembrane system organization GO:0010256 147 0.018
divalent metal ion transport GO:0070838 172 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
cation transport GO:0006812 399 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
lymphocyte differentiation GO:0030098 242 0.017
cation transmembrane transport GO:0098655 266 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
oxidation reduction process GO:0055114 342 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
regulation of secretion GO:0051046 274 0.017
meiotic cell cycle process GO:1903046 77 0.017
meiosis i GO:0007127 60 0.017
mitotic nuclear division GO:0007067 48 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
chromatin organization GO:0006325 206 0.017
cellular protein catabolic process GO:0044257 155 0.017
lipid biosynthetic process GO:0008610 179 0.017
regulation of protein maturation GO:1903317 96 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
ras protein signal transduction GO:0007265 77 0.017
negative regulation of cell cycle phase transition GO:1901988 48 0.017
nuclear transport GO:0051169 139 0.017
regulation of system process GO:0044057 200 0.017
leukocyte mediated immunity GO:0002443 174 0.016
action potential GO:0001508 78 0.016
protein processing GO:0016485 163 0.016
multicellular organism growth GO:0035264 161 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
intracellular protein transport GO:0006886 204 0.016
regulation of protein catabolic process GO:0042176 108 0.016
negative regulation of organelle organization GO:0010639 90 0.016
multicellular organismal signaling GO:0035637 91 0.016
gland development GO:0048732 330 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
striated muscle tissue development GO:0014706 293 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
adaptive immune response GO:0002250 155 0.016
histone modification GO:0016570 159 0.016
cellular homeostasis GO:0019725 240 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
regulation of cellular protein catabolic process GO:1903362 61 0.016
chromatin modification GO:0016568 187 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
meiotic nuclear division GO:0007126 115 0.015
maintenance of location GO:0051235 89 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
regulation of cell activation GO:0050865 289 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of hydrolase activity GO:0051336 246 0.015
lateral inhibition GO:0046331 1 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
organophosphate catabolic process GO:0046434 232 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
meiotic cell cycle GO:0051321 122 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
cellular response to peptide GO:1901653 92 0.014
cell activation involved in immune response GO:0002263 126 0.014
cell division GO:0051301 120 0.014
regulation of kinase activity GO:0043549 249 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
transmission of nerve impulse GO:0019226 76 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
receptor mediated endocytosis GO:0006898 51 0.014
anatomical structure homeostasis GO:0060249 145 0.014
purine containing compound catabolic process GO:0072523 213 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
nitrogen compound transport GO:0071705 271 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
regulation of mapk cascade GO:0043408 248 0.014
protein methylation GO:0006479 81 0.014
stem cell development GO:0048864 219 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
immune effector process GO:0002252 321 0.014
cell cycle checkpoint GO:0000075 47 0.014
glycosylation GO:0070085 62 0.014
response to peptide GO:1901652 136 0.014
macromolecule methylation GO:0043414 120 0.014
mapk cascade GO:0000165 281 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
regulation of transferase activity GO:0051338 263 0.013
protein alkylation GO:0008213 81 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
leukocyte proliferation GO:0070661 172 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
negative regulation of protein processing GO:0010955 79 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
skeletal system development GO:0001501 356 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
negative regulation of protein maturation GO:1903318 79 0.013
membrane organization GO:0061024 245 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of protein processing GO:0070613 96 0.013
stem cell differentiation GO:0048863 268 0.013
calcium ion transport GO:0006816 159 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
organic anion transport GO:0015711 137 0.013
ion transmembrane transport GO:0034220 361 0.012
positive regulation of cell activation GO:0050867 158 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
locomotory behavior GO:0007626 195 0.012
regulation of secretion by cell GO:1903530 249 0.012
regulation of t cell activation GO:0050863 170 0.012
oocyte construction GO:0007308 2 0.012
male anatomical structure morphogenesis GO:0090598 4 0.012
metal ion homeostasis GO:0055065 189 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
sequestering of calcium ion GO:0051208 18 0.012
innate immune response GO:0045087 157 0.012
dna catabolic process endonucleolytic GO:0000737 15 0.012
negative regulation of nuclear division GO:0051784 19 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
regulation of cytokine production GO:0001817 266 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
inflammatory response GO:0006954 244 0.012
histone lysine methylation GO:0034968 50 0.012
cellular ion homeostasis GO:0006873 165 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of protein localization GO:0032880 231 0.012
fat cell differentiation GO:0045444 160 0.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
regulation of neuron differentiation GO:0045664 281 0.012
microtubule cytoskeleton organization GO:0000226 157 0.011
anion transport GO:0006820 177 0.011
lymphocyte proliferation GO:0046651 164 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
protein targeting GO:0006605 143 0.011
positive regulation of immune effector process GO:0002699 107 0.011
carbohydrate metabolic process GO:0005975 230 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
nucleoside metabolic process GO:0009116 246 0.011
immunoglobulin production GO:0002377 73 0.011
respiratory system development GO:0060541 190 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
forebrain development GO:0030900 302 0.011
blood vessel morphogenesis GO:0048514 285 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
chromosome separation GO:0051304 14 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
cellular lipid metabolic process GO:0044255 323 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
macromolecule glycosylation GO:0043413 55 0.011
protein localization to organelle GO:0033365 185 0.011
negative regulation of proteolysis GO:0045861 74 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
cellular protein complex assembly GO:0043623 116 0.011
spermatogenesis GO:0007283 284 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
covalent chromatin modification GO:0016569 163 0.011
germ cell development GO:0007281 185 0.010
tissue homeostasis GO:0001894 115 0.010
protein polymerization GO:0051258 57 0.010
protein import GO:0017038 101 0.010
positive regulation of cell development GO:0010720 237 0.010
muscle tissue development GO:0060537 308 0.010
chemotaxis GO:0006935 247 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
ossification GO:0001503 216 0.010
cartilage development GO:0051216 140 0.010
negative regulation of dna replication GO:0008156 4 0.010
digestive system development GO:0055123 200 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
regulation of defense response GO:0031347 233 0.010
intracellular mrna localization GO:0008298 4 0.010
t cell differentiation GO:0030217 174 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
response to insulin GO:0032868 100 0.010
sequestering of metal ion GO:0051238 19 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
b cell differentiation GO:0030183 78 0.010
positive regulation of t cell activation GO:0050870 101 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
cellular response to acid chemical GO:0071229 68 0.010

Polh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
immune system disease DOID:2914 0 0.025
nervous system disease DOID:863 0 0.024
hematopoietic system disease DOID:74 0 0.022
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
central nervous system disease DOID:331 0 0.015
musculoskeletal system disease DOID:17 0 0.014
neurodegenerative disease DOID:1289 0 0.011