Mus musculus

0 known processes

Polr2a

polymerase (RNA) II (DNA directed) polypeptide A

(Aliases: Rpo2-1,220kDa,Rpb1)

Polr2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 187 0.952
chromatin organization GO:0006325 206 0.934
protein methylation GO:0006479 81 0.877
Worm
histone lysine methylation GO:0034968 50 0.780
gene silencing GO:0016458 38 0.759
dna metabolic process GO:0006259 303 0.749
covalent chromatin modification GO:0016569 163 0.723
histone modification GO:0016570 159 0.711
posttranscriptional regulation of gene expression GO:0010608 155 0.667
regulation of cell cycle GO:0051726 281 0.605
Fly
macromolecule methylation GO:0043414 120 0.563
Worm
stem cell differentiation GO:0048863 268 0.530
posttranscriptional gene silencing GO:0016441 10 0.518
gene silencing by rna GO:0031047 19 0.510
cellular response to dna damage stimulus GO:0006974 207 0.492
Fly
posttranscriptional gene silencing by rna GO:0035194 10 0.472
regulation of chromosome organization GO:0033044 83 0.465
histone methylation GO:0016571 71 0.419
negative regulation of cell proliferation GO:0008285 296 0.414
methylation GO:0032259 134 0.411
Worm
peptidyl lysine modification GO:0018205 77 0.395
gonad development GO:0008406 141 0.360
regionalization GO:0003002 337 0.360
regulation of cell cycle process GO:0010564 160 0.346
Fly
protein dna complex disassembly GO:0032986 1 0.340
mitotic cell cycle GO:0000278 195 0.338
Worm Fly
regulation of protein stability GO:0031647 52 0.325
regulation of chromatin modification GO:1903308 57 0.321
stem cell maintenance GO:0019827 130 0.317
cellular ketone metabolic process GO:0042180 84 0.306
stem cell development GO:0048864 219 0.305
rna interference GO:0016246 2 0.304
peptidyl amino acid modification GO:0018193 336 0.277
epithelial cell proliferation GO:0050673 174 0.267
development of primary sexual characteristics GO:0045137 143 0.266
negative regulation of protein metabolic process GO:0051248 282 0.262
regulation of mitotic cell cycle GO:0007346 126 0.259
Fly
internal peptidyl lysine acetylation GO:0018393 42 0.248
fibroblast proliferation GO:0048144 35 0.244
spermatogenesis GO:0007283 284 0.241
regulation of fibroblast proliferation GO:0048145 34 0.228
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.212
protein acylation GO:0043543 64 0.201
negative regulation of protein modification process GO:0031400 163 0.191
apoptotic signaling pathway GO:0097190 306 0.187
male gamete generation GO:0048232 285 0.184
muscle cell differentiation GO:0042692 261 0.181
meiotic cell cycle GO:0051321 122 0.174
multicellular organism growth GO:0035264 161 0.170
internal protein amino acid acetylation GO:0006475 42 0.170
embryonic skeletal system development GO:0048706 120 0.169
appendage development GO:0048736 166 0.169
dna templated transcription elongation GO:0006354 13 0.167
regulation of epithelial cell proliferation GO:0050678 141 0.163
regulation of binding GO:0051098 111 0.161
gland development GO:0048732 330 0.158
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.154
negative regulation of cellular protein metabolic process GO:0032269 247 0.150
nucleosome disassembly GO:0006337 1 0.147
skeletal system development GO:0001501 356 0.146
epithelial tube morphogenesis GO:0060562 303 0.146
retina development in camera type eye GO:0060041 119 0.144
purine ribonucleotide metabolic process GO:0009150 290 0.144
blastocyst development GO:0001824 80 0.141
regulation of histone modification GO:0031056 56 0.141
t cell differentiation GO:0030217 174 0.140
histone acetylation GO:0016573 41 0.139
cellular amine metabolic process GO:0044106 44 0.137
embryonic organ morphogenesis GO:0048562 276 0.136
cellular response to lipid GO:0071396 145 0.134
chemotaxis GO:0006935 247 0.134
genitalia development GO:0048806 37 0.132
histone h4 acetylation GO:0043967 10 0.130
development of primary female sexual characteristics GO:0046545 73 0.130
leukocyte differentiation GO:0002521 342 0.128
germ cell development GO:0007281 185 0.127
rhythmic process GO:0048511 174 0.127
negative regulation of cell cycle GO:0045786 123 0.124
Fly
ovarian follicle development GO:0001541 40 0.124
t cell activation GO:0042110 289 0.120
female sex differentiation GO:0046660 84 0.118
neural tube development GO:0021915 160 0.116
regulation of cellular ketone metabolic process GO:0010565 66 0.115
cell division GO:0051301 120 0.112
Worm
blood vessel morphogenesis GO:0048514 285 0.112
histone h3 acetylation GO:0043966 14 0.112
digestive tract development GO:0048565 190 0.109
Worm
bone development GO:0060348 120 0.109
limb development GO:0060173 166 0.108
intracellular receptor signaling pathway GO:0030522 74 0.106
notch signaling pathway GO:0007219 71 0.106
chromatin disassembly GO:0031498 1 0.106
urogenital system development GO:0001655 261 0.105
b cell activation GO:0042113 161 0.104
development of primary male sexual characteristics GO:0046546 88 0.103
regulation of organ morphogenesis GO:2000027 144 0.102
male sex differentiation GO:0046661 109 0.101
segmentation GO:0035282 93 0.101
protein modification by small protein conjugation or removal GO:0070647 207 0.101
aromatic compound catabolic process GO:0019439 286 0.100
cell fate commitment GO:0045165 210 0.100
regulation of androgen receptor signaling pathway GO:0060765 3 0.100
positive regulation of cellular amine metabolic process GO:0033240 5 0.099
regulation of kinase activity GO:0043549 249 0.099
epithelial cell development GO:0002064 159 0.099
sensory organ morphogenesis GO:0090596 242 0.096
morphogenesis of a branching epithelium GO:0061138 193 0.095
cellular nitrogen compound catabolic process GO:0044270 280 0.094
protein alkylation GO:0008213 81 0.093
Worm
regulation of cytoplasmic transport GO:1903649 112 0.092
organelle fission GO:0048285 170 0.091
Worm
response to organic cyclic compound GO:0014070 198 0.090
cellular amino acid metabolic process GO:0006520 103 0.090
cellular response to organonitrogen compound GO:0071417 145 0.089
regulation of organelle organization GO:0033043 289 0.088
amine metabolic process GO:0009308 45 0.088
lymphocyte differentiation GO:0030098 242 0.088
striated muscle tissue development GO:0014706 293 0.087
regulation of cellular response to stress GO:0080135 159 0.087
branching morphogenesis of an epithelial tube GO:0048754 159 0.086
blastocyst growth GO:0001832 23 0.086
dna recombination GO:0006310 92 0.085
macromolecule catabolic process GO:0009057 281 0.085
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.083
mammary gland epithelium development GO:0061180 65 0.083
ribonucleoside metabolic process GO:0009119 245 0.083
regulation of cellular amino acid metabolic process GO:0006521 5 0.081
protein catabolic process GO:0030163 221 0.081
positive regulation of epithelial cell proliferation GO:0050679 68 0.078
response to light stimulus GO:0009416 135 0.078
regulation of chromatin organization GO:1902275 57 0.077
appendage morphogenesis GO:0035107 149 0.076
heart morphogenesis GO:0003007 178 0.076
chromatin remodeling GO:0006338 32 0.074
mitotic cell cycle process GO:1903047 159 0.074
Worm Fly
negative regulation of phosphorylation GO:0042326 166 0.073
mrna metabolic process GO:0016071 84 0.072
myeloid cell differentiation GO:0030099 233 0.072
oocyte axis specification GO:0007309 2 0.071
transdifferentiation GO:0060290 1 0.071
neuroblast differentiation GO:0014016 2 0.070
regulation of cellular amine metabolic process GO:0033238 20 0.070
morphogenesis of a branching structure GO:0001763 203 0.070
positive regulation of notch signaling pathway GO:0045747 18 0.069
pigmentation GO:0043473 71 0.068
response to radiation GO:0009314 165 0.067
negative regulation of nervous system development GO:0051961 156 0.067
regulation of histone methylation GO:0031060 30 0.066
meiotic nuclear division GO:0007126 115 0.066
circadian rhythm GO:0007623 114 0.066
regulation of response to dna damage stimulus GO:2001020 34 0.066
chromatin assembly GO:0031497 13 0.065
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.064
response to steroid hormone GO:0048545 56 0.064
positive regulation of programmed cell death GO:0043068 218 0.063
nuclear division GO:0000280 158 0.063
Worm
axon guidance GO:0007411 141 0.063
positive regulation of protein modification process GO:0031401 299 0.063
multi multicellular organism process GO:0044706 109 0.062
nucleoside phosphate metabolic process GO:0006753 338 0.062
neuroblast fate determination GO:0007400 1 0.062
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.062
modification dependent macromolecule catabolic process GO:0043632 133 0.062
dna modification GO:0006304 50 0.062
developmental maturation GO:0021700 193 0.062
negative regulation of epithelial cell proliferation GO:0050680 64 0.061
camera type eye development GO:0043010 266 0.061
response to oxidative stress GO:0006979 123 0.061
regulation of notch signaling pathway GO:0008593 35 0.060
production of molecular mediator of immune response GO:0002440 103 0.060
neural tube formation GO:0001841 108 0.060
ovulation cycle GO:0042698 59 0.059
hexose metabolic process GO:0019318 98 0.058
cell maturation GO:0048469 127 0.058
dna conformation change GO:0071103 37 0.058
skeletal system morphogenesis GO:0048705 203 0.058
compound eye development GO:0048749 1 0.057
dna methylation GO:0006306 43 0.057
regulation of protein kinase activity GO:0045859 232 0.056
positive regulation of fibroblast proliferation GO:0048146 20 0.056
microtubule cytoskeleton organization GO:0000226 157 0.056
Worm
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.056
ossification GO:0001503 216 0.056
organonitrogen compound biosynthetic process GO:1901566 192 0.055
wnt signaling pathway GO:0016055 188 0.055
histone h4 k16 acetylation GO:0043984 3 0.055
cation transport GO:0006812 399 0.054
lipid biosynthetic process GO:0008610 179 0.054
cellular response to hormone stimulus GO:0032870 150 0.054
cellular lipid metabolic process GO:0044255 323 0.053
rna processing GO:0006396 105 0.053
neural precursor cell proliferation GO:0061351 121 0.053
positive regulation of apoptotic process GO:0043065 217 0.053
ribonucleotide metabolic process GO:0009259 291 0.053
cardiac cell fate specification GO:0060912 2 0.052
purine nucleoside metabolic process GO:0042278 241 0.052
purine containing compound metabolic process GO:0072521 311 0.052
positive regulation of binding GO:0051099 49 0.052
nucleocytoplasmic transport GO:0006913 139 0.052
regulation of cell division GO:0051302 76 0.051
male gonad development GO:0008584 88 0.051
determination of adult lifespan GO:0008340 11 0.051
axonogenesis GO:0007409 274 0.050
cytoplasmic transport GO:0016482 234 0.050
cellular response to acid chemical GO:0071229 68 0.050
negative regulation of secretion GO:0051048 61 0.050
neuron projection guidance GO:0097485 141 0.049
small gtpase mediated signal transduction GO:0007264 97 0.049
body morphogenesis GO:0010171 45 0.049
renal system development GO:0072001 225 0.049
negative regulation of molecular function GO:0044092 258 0.049
glycosyl compound metabolic process GO:1901657 246 0.049
oocyte differentiation GO:0009994 35 0.049
tube formation GO:0035148 140 0.049
ribonucleotide catabolic process GO:0009261 208 0.049
purine ribonucleotide catabolic process GO:0009154 208 0.048
cellular response to steroid hormone stimulus GO:0071383 33 0.048
nucleoside metabolic process GO:0009116 246 0.048
lung development GO:0030324 164 0.048
myeloid leukocyte differentiation GO:0002573 119 0.048
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.047
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.046
regulation of transferase activity GO:0051338 263 0.046
negative regulation of protein phosphorylation GO:0001933 126 0.046
regulation of lymphocyte differentiation GO:0045619 107 0.046
regulation of purine nucleotide metabolic process GO:1900542 169 0.046
female gonad development GO:0008585 71 0.046
protein localization to organelle GO:0033365 185 0.045
regulation of intracellular protein transport GO:0033157 82 0.045
gliogenesis GO:0042063 141 0.044
regulation of mrna metabolic process GO:1903311 43 0.044
regulation of protein localization GO:0032880 231 0.044
regulation of leukocyte differentiation GO:1902105 159 0.044
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.044
cellular response to growth factor stimulus GO:0071363 197 0.044
regulation of intracellular transport GO:0032386 159 0.043
immunoglobulin production GO:0002377 73 0.043
protein ubiquitination GO:0016567 171 0.043
purine nucleotide catabolic process GO:0006195 211 0.043
positive regulation of cell death GO:0010942 224 0.042
protein dna complex subunit organization GO:0071824 28 0.042
peptidyl serine modification GO:0018209 83 0.042
positive regulation of immature t cell proliferation GO:0033091 4 0.042
digestive system development GO:0055123 200 0.041
Worm
dna repair GO:0006281 107 0.041
cellular response to organic cyclic compound GO:0071407 87 0.041
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.041
cell type specific apoptotic process GO:0097285 268 0.041
regulation of stem cell differentiation GO:2000736 50 0.041
respiratory tube development GO:0030323 167 0.041
microtubule based process GO:0007017 236 0.041
Worm
mrna splicing via spliceosome GO:0000398 43 0.041
negative regulation of cell size GO:0045792 3 0.040
response to organonitrogen compound GO:0010243 246 0.040
cardiac ventricle development GO:0003231 83 0.040
carbohydrate metabolic process GO:0005975 230 0.040
embryonic skeletal system morphogenesis GO:0048704 91 0.040
cardiac chamber morphogenesis GO:0003206 93 0.040
protein autophosphorylation GO:0046777 61 0.040
gastrulation GO:0007369 116 0.040
Worm
maintenance of location GO:0051235 89 0.039
g1 s transition of mitotic cell cycle GO:0000082 57 0.039
somatic diversification of immune receptors GO:0002200 53 0.039
connective tissue development GO:0061448 179 0.039
embryonic appendage morphogenesis GO:0035113 126 0.039
modification dependent protein catabolic process GO:0019941 133 0.039
locomotory behavior GO:0007626 195 0.039
carbohydrate derivative catabolic process GO:1901136 231 0.039
placenta development GO:0001890 140 0.039
positive regulation of dna templated transcription elongation GO:0032786 2 0.038
glial cell differentiation GO:0010001 131 0.038
regulation of neuron death GO:1901214 134 0.037
organ growth GO:0035265 117 0.037
regulation of proteolysis GO:0030162 164 0.037
histone deacetylation GO:0016575 26 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
muscle tissue development GO:0060537 308 0.037
positive regulation of nucleotide metabolic process GO:0045981 114 0.037
response to acid chemical GO:0001101 111 0.037
homeostasis of number of cells GO:0048872 210 0.037
organic cyclic compound catabolic process GO:1901361 295 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
negative regulation of cell development GO:0010721 169 0.036
neural tube closure GO:0001843 90 0.036
response to oxygen levels GO:0070482 62 0.036
muscle cell development GO:0055001 133 0.036
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.036
regulation of lymphocyte mediated immunity GO:0002706 84 0.035
peptidyl lysine acetylation GO:0018394 45 0.035
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.035
t cell differentiation in thymus GO:0033077 77 0.035
nitrogen compound transport GO:0071705 271 0.035
negative regulation of intracellular signal transduction GO:1902532 167 0.035
negative regulation of cell fate specification GO:0009996 4 0.035
peptidyl lysine methylation GO:0018022 29 0.035
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.035
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.035
nucleobase containing compound transport GO:0015931 27 0.035
positive regulation of cell cycle GO:0045787 92 0.035
establishment of protein localization to organelle GO:0072594 118 0.035
regulation of cell cycle phase transition GO:1901987 77 0.035
Fly
carbohydrate derivative biosynthetic process GO:1901137 183 0.034
purine nucleotide metabolic process GO:0006163 302 0.034
adaptive immune response GO:0002250 155 0.034
second messenger mediated signaling GO:0019932 73 0.034
lymphocyte mediated immunity GO:0002449 139 0.034
digestive tract morphogenesis GO:0048546 147 0.033
Worm
erythrocyte differentiation GO:0030218 88 0.033
limb morphogenesis GO:0035108 149 0.033
protein modification by small protein conjugation GO:0032446 187 0.033
embryonic limb morphogenesis GO:0030326 126 0.033
embryonic digit morphogenesis GO:0042733 56 0.033
angiogenesis GO:0001525 201 0.033
monosaccharide metabolic process GO:0005996 106 0.033
rho protein signal transduction GO:0007266 32 0.033
regulation of nucleocytoplasmic transport GO:0046822 73 0.033
cardiocyte differentiation GO:0035051 87 0.032
regulation of translation GO:0006417 71 0.032
b cell differentiation GO:0030183 78 0.032
nucleoside catabolic process GO:0009164 206 0.032
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.032
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.032
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.032
Worm
response to peptide hormone GO:0043434 127 0.032
chromosome segregation GO:0007059 48 0.032
oxidation reduction process GO:0055114 342 0.032
dna packaging GO:0006323 30 0.032
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.032
protein deacetylation GO:0006476 32 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.031
regulation of nucleoside metabolic process GO:0009118 130 0.031
regulation of neuron differentiation GO:0045664 281 0.031
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.031
sequestering of calcium ion GO:0051208 18 0.031
ameboidal type cell migration GO:0001667 128 0.031
cell fate specification GO:0001708 72 0.031
forebrain development GO:0030900 302 0.031
negative regulation of leukocyte differentiation GO:1902106 51 0.030
oocyte construction GO:0007308 2 0.030
signal transduction by p53 class mediator GO:0072331 51 0.030
positive regulation of gene silencing by mirna GO:2000637 1 0.030
lymphocyte activation involved in immune response GO:0002285 93 0.030
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.030
immunoglobulin mediated immune response GO:0016064 69 0.030
inflammatory response GO:0006954 244 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
regulation of chromatin silencing GO:0031935 2 0.030
mammary gland morphogenesis GO:0060443 54 0.030
mrna processing GO:0006397 63 0.030
negative regulation of kinase activity GO:0033673 81 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
regulation of striated muscle cell differentiation GO:0051153 81 0.029
interspecies interaction between organisms GO:0044419 83 0.029
cellular macromolecule catabolic process GO:0044265 206 0.029
regulation of protein binding GO:0043393 60 0.029
neuron death GO:0070997 154 0.029
protein deacylation GO:0035601 36 0.029
dna alkylation GO:0006305 43 0.029
mesenchyme development GO:0060485 152 0.029
actin cytoskeleton organization GO:0030036 220 0.029
hematopoietic progenitor cell differentiation GO:0002244 143 0.029
chromatin mediated maintenance of transcription GO:0048096 2 0.029
androgen receptor signaling pathway GO:0030521 8 0.029
myotube differentiation GO:0014902 105 0.028
viral process GO:0016032 41 0.028
hexose biosynthetic process GO:0019319 39 0.028
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
regulation of mitotic cell cycle phase transition GO:1901990 73 0.028
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.028
regulation of multi organism process GO:0043900 111 0.028
establishment or maintenance of cell polarity GO:0007163 86 0.028
epithelial tube formation GO:0072175 130 0.028
female gamete generation GO:0007292 74 0.028
ribonucleotide biosynthetic process GO:0009260 59 0.027
negative regulation of mitotic cell cycle GO:0045930 58 0.027
Fly
purine ribonucleotide biosynthetic process GO:0009152 59 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
heterocycle catabolic process GO:0046700 280 0.027
negative regulation of immune system process GO:0002683 209 0.027
chromatin assembly or disassembly GO:0006333 16 0.027
spermatid development GO:0007286 108 0.027
regulation of lipid metabolic process GO:0019216 118 0.027
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.027
regulation of secretion GO:0051046 274 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.027
proteasomal protein catabolic process GO:0010498 98 0.027
negative regulation of cell cycle phase transition GO:1901988 48 0.027
Fly
regulation of dna binding GO:0051101 39 0.027
negative regulation of dna replication GO:0008156 4 0.027
embryonic placenta development GO:0001892 98 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.026
striated muscle cell development GO:0055002 125 0.026
regulation of ossification GO:0030278 112 0.026
gluconeogenesis GO:0006094 39 0.026
regulation of myeloid cell differentiation GO:0045637 96 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
somatic cell dna recombination GO:0016444 51 0.026
dna replication GO:0006260 52 0.026
positive regulation of proteolysis GO:0045862 85 0.026
negative regulation of transferase activity GO:0051348 85 0.026
glial cell fate determination GO:0007403 3 0.026
regulation of hippo signaling GO:0035330 1 0.026
isotype switching GO:0045190 36 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.025
skeletal muscle organ development GO:0060538 163 0.025
nucleotide metabolic process GO:0009117 332 0.025
carbohydrate biosynthetic process GO:0016051 74 0.025
cell aging GO:0007569 35 0.025
blastocyst formation GO:0001825 33 0.025
response to growth factor GO:0070848 198 0.025
neuronal action potential GO:0019228 54 0.025
response to peptide GO:1901652 136 0.025
hepaticobiliary system development GO:0061008 67 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
nucleotide catabolic process GO:0009166 217 0.025
neural retina development GO:0003407 41 0.025
nucleic acid transport GO:0050657 18 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.025
ectodermal cell differentiation GO:0010668 3 0.025
positive regulation of chromosome organization GO:2001252 33 0.024
positive regulation of nucleoside metabolic process GO:0045979 91 0.024
cellular response to peptide hormone stimulus GO:0071375 92 0.024
cellular response to gamma radiation GO:0071480 4 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
cardiac right ventricle formation GO:0003219 3 0.024
spermatid differentiation GO:0048515 115 0.024
cellular response to external stimulus GO:0071496 88 0.024
positive regulation of mitotic cell cycle GO:0045931 41 0.024
regulation of fat cell differentiation GO:0045598 81 0.024
regulation of secretion by cell GO:1903530 249 0.024
cell cycle arrest GO:0007050 37 0.024
negative regulation of t cell activation GO:0050868 65 0.024
immune effector process GO:0002252 321 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
inner cell mass cell proliferation GO:0001833 15 0.023
myeloid cell homeostasis GO:0002262 114 0.023
steroid metabolic process GO:0008202 119 0.023
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.023
cell substrate adhesion GO:0031589 130 0.023
hindbrain development GO:0030902 128 0.023
translation GO:0006412 93 0.023
regulation of cell motility GO:2000145 236 0.023
stem cell fate determination GO:0048867 2 0.023
negative regulation of lipid metabolic process GO:0045833 30 0.023
cartilage development GO:0051216 140 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
regulation of membrane potential GO:0042391 192 0.023
asymmetric stem cell division GO:0098722 3 0.023
cellular protein catabolic process GO:0044257 155 0.023
sensory perception of sound GO:0007605 97 0.023
regulation of nuclear division GO:0051783 56 0.023
transmission of nerve impulse GO:0019226 76 0.023
regulation of hydrolase activity GO:0051336 246 0.022
positive regulation of chromatin modification GO:1903310 28 0.022
regulation of protein transport GO:0051223 163 0.022
regulation of rna splicing GO:0043484 37 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
regulation of rho gtpase activity GO:0032319 58 0.022
establishment of rna localization GO:0051236 18 0.022
negative regulation of cell cycle process GO:0010948 69 0.022
Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.022
alpha beta t cell differentiation GO:0046632 69 0.022
protein import into nucleus GO:0006606 95 0.022
cellular response to insulin stimulus GO:0032869 78 0.022
t cell proliferation GO:0042098 120 0.022
response to insulin GO:0032868 100 0.022
dna templated transcription initiation GO:0006352 13 0.022
ear development GO:0043583 200 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
cardiac muscle tissue development GO:0048738 130 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.022
regulation of cell fate commitment GO:0010453 19 0.022
liver development GO:0001889 66 0.022
protein stabilization GO:0050821 25 0.021
ion transmembrane transport GO:0034220 361 0.021
respiratory system development GO:0060541 190 0.021
intracellular protein transport GO:0006886 204 0.021

Polr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.188
disease of cellular proliferation DOID:14566 0 0.188
organ system cancer DOID:0050686 0 0.154
disease of anatomical entity DOID:7 0 0.052
nervous system disease DOID:863 0 0.052
immune system cancer DOID:0060083 0 0.038
hematologic cancer DOID:2531 0 0.038
auditory system disease DOID:2742 0 0.032
nonsyndromic deafness DOID:0050563 0 0.032
sensory system disease DOID:0050155 0 0.032
gastrointestinal system cancer DOID:3119 0 0.022
intestinal cancer DOID:10155 0 0.021