Mus musculus

0 known processes

Polr2b

polymerase (RNA) II (DNA directed) polypeptide B

(Aliases: MGC47046,Rpb140,Rpb2,Pol2rb)

Polr2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.151
rna processing GO:0006396 105 0.124
dna repair GO:0006281 107 0.099
organelle fission GO:0048285 170 0.093
somatic diversification of immunoglobulins GO:0016445 43 0.090
stem cell development GO:0048864 219 0.081
gene silencing by rna GO:0031047 19 0.067
axonogenesis GO:0007409 274 0.066
ncrna 3 end processing GO:0043628 2 0.065
stem cell differentiation GO:0048863 268 0.061
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.061
rna splicing via transesterification reactions GO:0000375 43 0.061
mitotic nuclear division GO:0007067 48 0.061
nucleoside metabolic process GO:0009116 246 0.061
cellular nitrogen compound catabolic process GO:0044270 280 0.060
posttranscriptional regulation of gene expression GO:0010608 155 0.057
cellular amino acid metabolic process GO:0006520 103 0.055
rna splicing GO:0008380 54 0.054
endocytosis GO:0006897 168 0.053
aromatic compound catabolic process GO:0019439 286 0.051
mitotic cell cycle process GO:1903047 159 0.051
atp catabolic process GO:0006200 55 0.049
nuclear division GO:0000280 158 0.049
regulation of cellular response to stress GO:0080135 159 0.048
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.045
mitotic cell cycle GO:0000278 195 0.045
chromatin organization GO:0006325 206 0.045
organelle assembly GO:0070925 177 0.045
ras protein signal transduction GO:0007265 77 0.044
microtubule based process GO:0007017 236 0.043
peptidyl amino acid modification GO:0018193 336 0.041
cell type specific apoptotic process GO:0097285 268 0.040
defense response to other organism GO:0098542 197 0.040
atp metabolic process GO:0046034 75 0.040
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.039
purine nucleoside monophosphate catabolic process GO:0009128 58 0.038
regulation of organelle organization GO:0033043 289 0.038
purine nucleotide metabolic process GO:0006163 302 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
organophosphate catabolic process GO:0046434 232 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
purine nucleotide catabolic process GO:0006195 211 0.035
nucleoside monophosphate catabolic process GO:0009125 59 0.035
apoptotic signaling pathway GO:0097190 306 0.035
histone modification GO:0016570 159 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.034
histone lysine methylation GO:0034968 50 0.033
negative regulation of histone h3 k9 methylation GO:0051573 4 0.032
ribonucleoside monophosphate catabolic process GO:0009158 57 0.032
ribonucleotide catabolic process GO:0009261 208 0.032
posttranscriptional gene silencing GO:0016441 10 0.031
heterocycle catabolic process GO:0046700 280 0.031
germ cell development GO:0007281 185 0.031
microtubule cytoskeleton organization GO:0000226 157 0.030
regulation of chromosome organization GO:0033044 83 0.030
double strand break repair GO:0006302 48 0.030
double strand break repair via nonhomologous end joining GO:0006303 10 0.029
mrna metabolic process GO:0016071 84 0.029
somatic diversification of immune receptors GO:0002200 53 0.028
production of molecular mediator of immune response GO:0002440 103 0.028
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.028
lymphocyte mediated immunity GO:0002449 139 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
regulation of chromatin modification GO:1903308 57 0.027
axon guidance GO:0007411 141 0.026
immune effector process GO:0002252 321 0.026
purine containing compound catabolic process GO:0072523 213 0.026
posttranscriptional gene silencing by rna GO:0035194 10 0.026
ribonucleoside catabolic process GO:0042454 206 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
purine nucleoside monophosphate metabolic process GO:0009126 81 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
intracellular protein transport GO:0006886 204 0.025
chemotaxis GO:0006935 247 0.025
development of primary sexual characteristics GO:0045137 143 0.025
purine containing compound metabolic process GO:0072521 311 0.024
snrna metabolic process GO:0016073 1 0.024
protein localization to nucleus GO:0034504 121 0.024
dna templated transcription termination GO:0006353 4 0.024
placenta development GO:0001890 140 0.024
nucleotide metabolic process GO:0009117 332 0.023
dna recombination GO:0006310 92 0.023
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.023
nucleotide catabolic process GO:0009166 217 0.023
gonad development GO:0008406 141 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.023
locomotory behavior GO:0007626 195 0.022
extrinsic apoptotic signaling pathway GO:0097191 126 0.022
neuron death GO:0070997 154 0.022
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.022
lateral inhibition GO:0046331 1 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
mesenchymal cell differentiation GO:0048762 107 0.022
response to organic cyclic compound GO:0014070 198 0.021
leukocyte activation involved in immune response GO:0002366 126 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
methylation GO:0032259 134 0.020
cytoplasmic transport GO:0016482 234 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.020
positive regulation of cell death GO:0010942 224 0.020
neuron projection guidance GO:0097485 141 0.020
rna phosphodiester bond hydrolysis GO:0090501 19 0.019
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
ameboidal type cell migration GO:0001667 128 0.019
negative regulation of cell proliferation GO:0008285 296 0.018
mrna splicing via spliceosome GO:0000398 43 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
trna wobble uridine modification GO:0002098 2 0.018
interspecies interaction between organisms GO:0044419 83 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
action potential GO:0001508 78 0.018
gene silencing GO:0016458 38 0.017
response to extracellular stimulus GO:0009991 127 0.017
regulation of actin filament based process GO:0032970 99 0.017
rna interference GO:0016246 2 0.017
trna aminoacylation GO:0043039 1 0.017
snrna 3 end processing GO:0034472 1 0.017
trna metabolic process GO:0006399 11 0.017
immunoglobulin production GO:0002377 73 0.017
positive regulation of growth GO:0045927 104 0.017
adult behavior GO:0030534 135 0.017
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.017
cell cycle checkpoint GO:0000075 47 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
receptor mediated endocytosis GO:0006898 51 0.017
protein acylation GO:0043543 64 0.017
establishment of protein localization to organelle GO:0072594 118 0.016
nucleotide excision repair GO:0006289 13 0.016
trna aminoacylation for protein translation GO:0006418 1 0.016
regulation of response to dna damage stimulus GO:2001020 34 0.016
cell activation involved in immune response GO:0002263 126 0.016
neuron apoptotic process GO:0051402 142 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
olfactory learning GO:0008355 2 0.015
ncrna processing GO:0034470 26 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
regulation of intracellular transport GO:0032386 159 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
stem cell maintenance GO:0019827 130 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
macromolecule methylation GO:0043414 120 0.015
mrna processing GO:0006397 63 0.014
protein localization to organelle GO:0033365 185 0.014
single fertilization GO:0007338 82 0.014
gland development GO:0048732 330 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
chromatin modification GO:0016568 187 0.014
fertilization GO:0009566 127 0.014
maintenance of location GO:0051235 89 0.014
multicellular organismal aging GO:0010259 24 0.013
response to transforming growth factor beta GO:0071559 88 0.013
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.013
leukocyte mediated immunity GO:0002443 174 0.013
maturation of ssu rrna GO:0030490 1 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
cellular protein complex assembly GO:0043623 116 0.013
protein processing GO:0016485 163 0.013
macromolecule catabolic process GO:0009057 281 0.013
multicellular organismal signaling GO:0035637 91 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
nuclear transcribed mrna catabolic process GO:0000956 16 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.013
maturation of 5 8s rrna GO:0000460 1 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
regulation of cell cycle phase transition GO:1901987 77 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
cell recognition GO:0008037 83 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
response to insulin GO:0032868 100 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.012
regulation of hormone levels GO:0010817 211 0.012
male gamete generation GO:0048232 285 0.012
snrna processing GO:0016180 1 0.012
cation transmembrane transport GO:0098655 266 0.012
molting cycle GO:0042303 90 0.012
maintenance of protein location in nucleus GO:0051457 2 0.012
leukocyte apoptotic process GO:0071887 71 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
regulation of histone modification GO:0031056 56 0.012
regulation of protein stability GO:0031647 52 0.012
amine metabolic process GO:0009308 45 0.012
positive regulation of nervous system development GO:0051962 221 0.012
divalent metal ion transport GO:0070838 172 0.012
trna wobble base modification GO:0002097 2 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of chromatin silencing GO:0031935 2 0.012
response to organonitrogen compound GO:0010243 246 0.012
protein deacetylation GO:0006476 32 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
regulation of cell growth GO:0001558 91 0.011
tubulin deacetylation GO:0090042 4 0.011
tissue homeostasis GO:0001894 115 0.011
negative regulation of molecular function GO:0044092 258 0.011
regulation of dna damage checkpoint GO:2000001 3 0.011
protein targeting GO:0006605 143 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of multi organism process GO:0043900 111 0.011
dna conformation change GO:0071103 37 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
meiotic cell cycle GO:0051321 122 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
cell adhesion GO:0007155 329 0.011
positive regulation of protein modification process GO:0031401 299 0.011
non recombinational repair GO:0000726 10 0.011
cell cell recognition GO:0009988 44 0.011
response to peptide GO:1901652 136 0.011
b cell activation involved in immune response GO:0002312 50 0.011
forebrain development GO:0030900 302 0.011
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.011
sperm egg recognition GO:0035036 37 0.010
response to light stimulus GO:0009416 135 0.010
trna processing GO:0008033 11 0.010
b cell activation GO:0042113 161 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
nitrogen compound transport GO:0071705 271 0.010
dendrite development GO:0016358 115 0.010
ribosomal small subunit biogenesis GO:0042274 4 0.010

Polr2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.107
disease of anatomical entity DOID:7 0 0.107
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.013
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011