Mus musculus

2 known processes

Ppa1

pyrophosphatase (inorganic) 1

(Aliases: Pyp,2010317E03Rik)

Ppa1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate biosynthetic process GO:0090407 122 0.444
dna metabolic process GO:0006259 303 0.316
purine ribonucleoside metabolic process GO:0046128 241 0.304
nucleoside phosphate metabolic process GO:0006753 338 0.263
mitochondrion organization GO:0007005 134 0.250
nucleoside triphosphate metabolic process GO:0009141 230 0.226
organonitrogen compound biosynthetic process GO:1901566 192 0.209
amine metabolic process GO:0009308 45 0.189
nucleoside metabolic process GO:0009116 246 0.184
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.179
nucleobase containing small molecule metabolic process GO:0055086 352 0.174
glycosyl compound metabolic process GO:1901657 246 0.174
nucleoside phosphate biosynthetic process GO:1901293 79 0.162
cellular amino acid metabolic process GO:0006520 103 0.159
ribose phosphate metabolic process GO:0019693 291 0.135
heterocycle catabolic process GO:0046700 280 0.131
cofactor transport GO:0051181 4 0.131
cellular amine metabolic process GO:0044106 44 0.126
purine nucleotide metabolic process GO:0006163 302 0.123
nucleotide metabolic process GO:0009117 332 0.123
transmembrane transport GO:0055085 412 0.121
cellular nitrogen compound catabolic process GO:0044270 280 0.118
small molecule biosynthetic process GO:0044283 132 0.117
ribonucleoside metabolic process GO:0009119 245 0.114
oxidation reduction process GO:0055114 342 0.113
cellular lipid metabolic process GO:0044255 323 0.108
purine containing compound metabolic process GO:0072521 311 0.099
cristae formation GO:0042407 3 0.098
positive regulation of peptidase activity GO:0010952 49 0.096
nucleotide biosynthetic process GO:0009165 78 0.095
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.092
cellular modified amino acid metabolic process GO:0006575 63 0.092
carbohydrate derivative biosynthetic process GO:1901137 183 0.090
cellular ketone metabolic process GO:0042180 84 0.086
purine nucleoside metabolic process GO:0042278 241 0.086
regulation of membrane potential GO:0042391 192 0.084
generation of precursor metabolites and energy GO:0006091 103 0.083
aromatic compound catabolic process GO:0019439 286 0.081
positive regulation of hydrolase activity GO:0051345 148 0.078
alpha amino acid metabolic process GO:1901605 59 0.073
cellular respiration GO:0045333 38 0.072
ribonucleotide biosynthetic process GO:0009260 59 0.071
purine ribonucleoside biosynthetic process GO:0046129 19 0.071
adenine nucleotide transport GO:0051503 2 0.070
ribonucleotide metabolic process GO:0009259 291 0.070
purine containing compound biosynthetic process GO:0072522 70 0.068
purine nucleoside biosynthetic process GO:0042451 19 0.066
positive regulation of cell death GO:0010942 224 0.065
regulation of defense response GO:0031347 233 0.064
energy derivation by oxidation of organic compounds GO:0015980 77 0.061
cellular response to dna damage stimulus GO:0006974 207 0.060
purine ribonucleotide metabolic process GO:0009150 290 0.060
organonitrogen compound catabolic process GO:1901565 264 0.059
glycerolipid metabolic process GO:0046486 122 0.059
t cell proliferation GO:0042098 120 0.058
response to organonitrogen compound GO:0010243 246 0.056
selenium compound metabolic process GO:0001887 3 0.055
ribose phosphate biosynthetic process GO:0046390 59 0.055
phosphatidylethanolamine metabolic process GO:0046337 2 0.054
organic acid biosynthetic process GO:0016053 86 0.053
protein catabolic process GO:0030163 221 0.053
atp metabolic process GO:0046034 75 0.053
purine nucleotide biosynthetic process GO:0006164 65 0.053
cytokine production GO:0001816 319 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
regulation of intracellular transport GO:0032386 159 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
inflammatory response GO:0006954 244 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
carboxylic acid biosynthetic process GO:0046394 86 0.049
anion transport GO:0006820 177 0.048
response to acid chemical GO:0001101 111 0.048
response to alcohol GO:0097305 48 0.048
development of primary sexual characteristics GO:0045137 143 0.047
cellular macromolecule catabolic process GO:0044265 206 0.047
membrane organization GO:0061024 245 0.046
ribonucleoside monophosphate metabolic process GO:0009161 80 0.046
purine ribonucleotide biosynthetic process GO:0009152 59 0.046
cellular biogenic amine metabolic process GO:0006576 28 0.046
t cell activation GO:0042110 289 0.046
negative regulation of alcohol biosynthetic process GO:1902931 4 0.046
lymphocyte mediated immunity GO:0002449 139 0.045
cellular protein complex assembly GO:0043623 116 0.045
regulation of organelle organization GO:0033043 289 0.045
apoptotic mitochondrial changes GO:0008637 48 0.044
divalent inorganic cation homeostasis GO:0072507 138 0.044
organic cyclic compound catabolic process GO:1901361 295 0.043
positive regulation of apoptotic process GO:0043065 217 0.043
negative regulation of immune system process GO:0002683 209 0.043
regulation of phospholipid biosynthetic process GO:0071071 3 0.043
positive regulation of cellular catabolic process GO:0031331 148 0.043
cellular calcium ion homeostasis GO:0006874 119 0.042
nucleotide catabolic process GO:0009166 217 0.042
nucleoside biosynthetic process GO:0009163 21 0.042
immune response regulating signaling pathway GO:0002764 125 0.042
protein import GO:0017038 101 0.041
positive regulation of programmed cell death GO:0043068 218 0.041
cytoplasmic transport GO:0016482 234 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.039
cellular homeostasis GO:0019725 240 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.038
regulation of cell activation GO:0050865 289 0.038
carbohydrate derivative catabolic process GO:1901136 231 0.037
regulation of t cell activation GO:0050863 170 0.037
cellular response to lipid GO:0071396 145 0.037
positive regulation of proteolysis GO:0045862 85 0.037
purine nucleoside monophosphate metabolic process GO:0009126 81 0.037
negative regulation of cellular amine metabolic process GO:0033239 1 0.037
lipid biosynthetic process GO:0008610 179 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.037
calcium ion homeostasis GO:0055074 127 0.036
glycosyl compound catabolic process GO:1901658 206 0.036
gland development GO:0048732 330 0.036
lymphocyte proliferation GO:0046651 164 0.035
mitochondrial transport GO:0006839 36 0.034
leukocyte proliferation GO:0070661 172 0.033
cellular metal ion homeostasis GO:0006875 151 0.033
regulation of cytokine production GO:0001817 266 0.033
gonad development GO:0008406 141 0.032
positive regulation of organelle organization GO:0010638 128 0.032
cellular chemical homeostasis GO:0055082 215 0.031
regulation of leukocyte differentiation GO:1902105 159 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
extracellular matrix organization GO:0030198 147 0.031
response to oxidative stress GO:0006979 123 0.030
response to extracellular stimulus GO:0009991 127 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
macromolecule catabolic process GO:0009057 281 0.030
regulation of endopeptidase activity GO:0052548 89 0.030
spindle assembly involved in mitosis GO:0090307 4 0.029
ion transmembrane transport GO:0034220 361 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
sperm egg recognition GO:0035036 37 0.029
myeloid leukocyte differentiation GO:0002573 119 0.029
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.029
cofactor metabolic process GO:0051186 80 0.029
purine nucleotide catabolic process GO:0006195 211 0.028
glycerophospholipid metabolic process GO:0006650 71 0.028
superoxide metabolic process GO:0006801 27 0.028
protein localization to mitochondrion GO:0070585 15 0.028
ribonucleoside biosynthetic process GO:0042455 21 0.028
regulation of blood pressure GO:0008217 93 0.028
leukocyte mediated immunity GO:0002443 174 0.027
proteasome assembly GO:0043248 1 0.027
neural precursor cell proliferation GO:0061351 121 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
cellular response to oxidative stress GO:0034599 76 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
locomotory behavior GO:0007626 195 0.026
immune effector process GO:0002252 321 0.026
carbohydrate homeostasis GO:0033500 128 0.026
negative regulation of molecular function GO:0044092 258 0.026
nucleoside monophosphate metabolic process GO:0009123 85 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.025
organic hydroxy compound biosynthetic process GO:1901617 77 0.025
metal ion homeostasis GO:0055065 189 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
apoptotic signaling pathway GO:0097190 306 0.025
organophosphate catabolic process GO:0046434 232 0.024
protein refolding GO:0042026 1 0.024
sensory organ morphogenesis GO:0090596 242 0.024
cell division GO:0051301 120 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
regulation of hydrolase activity GO:0051336 246 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
guanosine containing compound metabolic process GO:1901068 144 0.023
mitochondrial membrane organization GO:0007006 26 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
mapk cascade GO:0000165 281 0.022
myeloid cell differentiation GO:0030099 233 0.022
nuclear transport GO:0051169 139 0.022
protein localization to organelle GO:0033365 185 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
positive regulation of cell development GO:0010720 237 0.022
cation transport GO:0006812 399 0.022
spermatogenesis GO:0007283 284 0.022
phospholipid metabolic process GO:0006644 87 0.022
regulation of inflammatory response GO:0050727 147 0.022
regulation of transmembrane transport GO:0034762 128 0.021
regulation of leukocyte mediated immunity GO:0002703 104 0.021
extracellular structure organization GO:0043062 148 0.021
glycerophospholipid biosynthetic process GO:0046474 32 0.021
purine nucleotide transport GO:0015865 2 0.021
regulation of ion transmembrane transport GO:0034765 119 0.021
neuron apoptotic process GO:0051402 142 0.021
response to oxygen levels GO:0070482 62 0.021
positive regulation of protein modification process GO:0031401 299 0.020
protein methylation GO:0006479 81 0.020
endocytosis GO:0006897 168 0.020
alpha beta t cell activation GO:0046631 91 0.020
mitochondrial translation GO:0032543 4 0.020
phospholipid biosynthetic process GO:0008654 36 0.020
regulation of ion transport GO:0043269 215 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
monosaccharide metabolic process GO:0005996 106 0.020
multicellular organismal aging GO:0010259 24 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.020
divalent inorganic cation transport GO:0072511 178 0.019
protein alkylation GO:0008213 81 0.019
regulation of peptidase activity GO:0052547 96 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
organic anion transport GO:0015711 137 0.019
intracellular protein transport GO:0006886 204 0.019
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.019
regulation of anatomical structure size GO:0090066 178 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
innate immune response GO:0045087 157 0.019
negative regulation of defense response GO:0031348 77 0.018
regulation of hormone levels GO:0010817 211 0.018
peptidyl amino acid modification GO:0018193 336 0.018
nicotinamide nucleotide biosynthetic process GO:0019359 4 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
coenzyme biosynthetic process GO:0009108 23 0.018
glycerolipid biosynthetic process GO:0045017 50 0.018
regulation of t cell differentiation GO:0045580 83 0.018
regulation of kinase activity GO:0043549 249 0.018
blood circulation GO:0008015 195 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
regulation of response to biotic stimulus GO:0002831 38 0.018
protein polymerization GO:0051258 57 0.018
dna recombination GO:0006310 92 0.018
alcohol metabolic process GO:0006066 116 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
organophosphate ester transport GO:0015748 28 0.018
regulation of cell migration GO:0030334 219 0.017
activation of immune response GO:0002253 138 0.017
sodium ion transport GO:0006814 73 0.017
fertilization GO:0009566 127 0.017
liver development GO:0001889 66 0.017
purine containing compound catabolic process GO:0072523 213 0.017
b cell activation GO:0042113 161 0.017
pigment metabolic process GO:0042440 32 0.017
cell proliferation in external granule layer GO:0021924 10 0.016
cellular amino acid catabolic process GO:0009063 25 0.016
mitochondrion morphogenesis GO:0070584 13 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.016
regulation of cell motility GO:2000145 236 0.016
regulation of engulfment of apoptotic cell GO:1901074 2 0.016
mitochondrial calcium ion homeostasis GO:0051560 7 0.016
cellular response to carbohydrate stimulus GO:0071322 50 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
cellular glucose homeostasis GO:0001678 52 0.016
nucleoside catabolic process GO:0009164 206 0.016
cellular amide metabolic process GO:0043603 58 0.016
t cell differentiation GO:0030217 174 0.016
regulation of organ morphogenesis GO:2000027 144 0.016
pyridine nucleotide biosynthetic process GO:0019363 4 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
cell adhesion GO:0007155 329 0.016
cellular ion homeostasis GO:0006873 165 0.016
sulfur compound metabolic process GO:0006790 100 0.016
regulation of body fluid levels GO:0050878 162 0.016
cell type specific apoptotic process GO:0097285 268 0.015
leukocyte differentiation GO:0002521 342 0.015
regulation of cell projection organization GO:0031344 206 0.015
organelle localization GO:0051640 179 0.015
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.015
regulation of mitochondrion organization GO:0010821 27 0.015
oxidoreduction coenzyme metabolic process GO:0006733 16 0.015
positive regulation of cell activation GO:0050867 158 0.015
anatomical structure homeostasis GO:0060249 145 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
positive regulation of cytokine production GO:0001819 174 0.015
response to drug GO:0042493 75 0.015
sperm motility GO:0030317 47 0.015
glucose homeostasis GO:0042593 128 0.015
respiratory system development GO:0060541 190 0.015
respiratory burst GO:0045730 8 0.015
organelle fission GO:0048285 170 0.015
monocarboxylic acid biosynthetic process GO:0072330 61 0.014
protein oligomerization GO:0051259 67 0.014
protein export from nucleus GO:0006611 20 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
nuclear import GO:0051170 95 0.014
interleukin 6 production GO:0032635 58 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
regulation of blood vessel size GO:0050880 56 0.014
protein targeting GO:0006605 143 0.014
cation homeostasis GO:0055080 212 0.014
response to inorganic substance GO:0010035 96 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
calcium ion transport GO:0006816 159 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
regulation of cellular response to stress GO:0080135 159 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.014
nicotinamide nucleotide metabolic process GO:0046496 12 0.013
pyridine containing compound catabolic process GO:0072526 4 0.013
synaptic transmission GO:0007268 329 0.013
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901028 7 0.013
protein kinase b signaling GO:0043491 74 0.013
negative regulation of phospholipid biosynthetic process GO:0071072 1 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
regulation of transferase activity GO:0051338 263 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
positive regulation of cell adhesion GO:0045785 80 0.013
regulation of map kinase activity GO:0043405 120 0.013
regulation of myeloid leukocyte differentiation GO:0002761 58 0.013
response to metal ion GO:0010038 47 0.013
regulation of feeding behavior GO:0060259 3 0.013
nitrogen compound transport GO:0071705 271 0.013
response to amine GO:0014075 16 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
cell aging GO:0007569 35 0.013
response to testosterone GO:0033574 3 0.013
coenzyme metabolic process GO:0006732 52 0.013
immune response activating signal transduction GO:0002757 116 0.013
tissue homeostasis GO:0001894 115 0.013
neuron death GO:0070997 154 0.013
single fertilization GO:0007338 82 0.013
pentose phosphate shunt GO:0006098 2 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
response to monosaccharide GO:0034284 67 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
cofactor biosynthetic process GO:0051188 41 0.013
cellular response to acid chemical GO:0071229 68 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
cellular response to cytokine stimulus GO:0071345 189 0.012
cell substrate adhesion GO:0031589 130 0.012
genitalia development GO:0048806 37 0.012
regulation of cell adhesion GO:0030155 154 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
protein import into nucleus GO:0006606 95 0.012
cation transmembrane transport GO:0098655 266 0.012
negative regulation of leukocyte differentiation GO:1902106 51 0.012
cellular modified amino acid biosynthetic process GO:0042398 12 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of secretion by cell GO:1903530 249 0.012
cellular response to glucose stimulus GO:0071333 45 0.012
homeostasis of number of cells GO:0048872 210 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
small molecule catabolic process GO:0044282 71 0.012
response to organophosphorus GO:0046683 22 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
fatty acid metabolic process GO:0006631 121 0.012
mitochondrion degradation GO:0000422 3 0.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
forebrain development GO:0030900 302 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
macromolecule methylation GO:0043414 120 0.011
response to nutrient levels GO:0031667 109 0.011
inflammatory response to antigenic stimulus GO:0002437 30 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
pigment biosynthetic process GO:0046148 26 0.011
response to decreased oxygen levels GO:0036293 59 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
positive regulation of cell substrate adhesion GO:0010811 47 0.011
positive regulation of immune effector process GO:0002699 107 0.011
multicellular organism growth GO:0035264 161 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
regulation of tube size GO:0035150 57 0.011
regulation of transporter activity GO:0032409 57 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
regulation of systemic arterial blood pressure GO:0003073 61 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
receptor mediated endocytosis GO:0006898 51 0.010
gtp metabolic process GO:0046039 144 0.010
regulation of protein transport GO:0051223 163 0.010
immunoglobulin production GO:0002377 73 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
cytosolic calcium ion homeostasis GO:0051480 70 0.010

Ppa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.209
disease of anatomical entity DOID:7 0 0.209
disease of metabolism DOID:0014667 0 0.036
blood coagulation disease DOID:1247 0 0.029
hematopoietic system disease DOID:74 0 0.029
nervous system disease DOID:863 0 0.025
neuromuscular disease DOID:440 0 0.025
charcot marie tooth disease DOID:10595 0 0.025
neuropathy DOID:870 0 0.025
central nervous system disease DOID:331 0 0.016