Mus musculus

236 known processes

Prdm1

PR domain containing 1, with ZNF domain

(Aliases: Blimp-1,ZNFPR1A1,PRDI-BF1,Blimp1)

Prdm1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
adaptive immune response GO:0002250 155 0.922
regulation of inflammatory response GO:0050727 147 0.910
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.887
response to molecule of bacterial origin GO:0002237 143 0.887
immune response activating signal transduction GO:0002757 116 0.834
regulation of defense response GO:0031347 233 0.830
regulation of adaptive immune response GO:0002819 90 0.817
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.813
eosinophil activation involved in immune response GO:0002278 1 0.813
immune effector process GO:0002252 321 0.811
leukocyte activation involved in immune response GO:0002366 126 0.807
single organismal cell cell adhesion GO:0016337 131 0.802
regulation of leukocyte mediated immunity GO:0002703 104 0.762
inflammatory response GO:0006954 244 0.749
immune response regulating signaling pathway GO:0002764 125 0.727
activation of immune response GO:0002253 138 0.713
regulation of response to wounding GO:1903034 189 0.711
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.696
antigen receptor mediated signaling pathway GO:0050851 64 0.688
positive regulation of inflammatory response GO:0050729 47 0.684
cellular response to biotic stimulus GO:0071216 92 0.667
regulation of alpha beta t cell activation GO:0046634 53 0.648
cell activation involved in immune response GO:0002263 126 0.647
t cell differentiation GO:0030217 174 0.638
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.623
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.617
t cell extravasation GO:0072683 4 0.613
regulation of innate immune response GO:0045088 91 0.611
regulation of t cell costimulation GO:2000523 2 0.607
regulation of leukocyte proliferation GO:0070663 121 0.605
helper t cell chemotaxis GO:0035704 1 0.604
lymphocyte proliferation GO:0046651 164 0.585
myeloid leukocyte mediated immunity GO:0002444 42 0.567
positive regulation of immune effector process GO:0002699 107 0.555
positive regulation of immunological synapse formation GO:2000522 1 0.554
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.539
negative regulation of immune effector process GO:0002698 55 0.533
positive regulation of lymphocyte activation GO:0051251 140 0.528
positive regulation of response to wounding GO:1903036 66 0.523
positive regulation of monocyte extravasation GO:2000439 1 0.506
monocyte extravasation GO:0035696 2 0.499
leukocyte mediated immunity GO:0002443 174 0.494
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.485
positive regulation of defense response GO:0031349 124 0.481
epithelial tube morphogenesis GO:0060562 303 0.475
alpha beta t cell activation GO:0046631 91 0.473
negative regulation of cell activation GO:0050866 111 0.469
positive regulation of t cell extravasation GO:2000409 2 0.464
regulation of lymphocyte proliferation GO:0050670 117 0.447
alpha beta t cell differentiation GO:0046632 69 0.446
regulation of monocyte extravasation GO:2000437 2 0.443
regulation of t cell activation GO:0050863 170 0.441
lymphocyte activation involved in immune response GO:0002285 93 0.429
homeostasis of number of cells GO:0048872 210 0.421
t cell receptor signaling pathway GO:0050852 46 0.416
branching morphogenesis of an epithelial tube GO:0048754 159 0.412
organonitrogen compound catabolic process GO:1901565 264 0.409
wound healing GO:0042060 157 0.407
microglial cell activation GO:0001774 3 0.400
regulation of t cell extravasation GO:2000407 3 0.398
pattern recognition receptor signaling pathway GO:0002221 47 0.394
regulation of cell activation GO:0050865 289 0.392
forebrain development GO:0030900 302 0.385
regulation of immunological synapse formation GO:2000520 2 0.385
regulation of dendritic cell chemotaxis GO:2000508 1 0.374
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.373
morphogenesis of a branching structure GO:0001763 203 0.373
cellular response to lipopolysaccharide GO:0071222 77 0.373
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.370
leukocyte differentiation GO:0002521 342 0.367
immune complex clearance GO:0002434 2 0.361
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.355
blood circulation GO:0008015 195 0.355
eosinophil activation GO:0043307 1 0.352
t helper 17 cell chemotaxis GO:0035705 1 0.351
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.350
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.349
negative regulation of homeostatic process GO:0032845 71 0.342
eosinophil degranulation GO:0043308 1 0.339
positive regulation of cell activation GO:0050867 158 0.339
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.336
regulation of cytokine production GO:0001817 266 0.335
regulation of lymphocyte activation GO:0051249 240 0.333
regulation of eosinophil degranulation GO:0043309 1 0.333
acute inflammatory response GO:0002526 41 0.331
lymphocyte differentiation GO:0030098 242 0.327
b cell activation involved in immune response GO:0002312 50 0.325
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.322
positive regulation of t cell costimulation GO:2000525 2 0.322
microglial cell activation involved in immune response GO:0002282 1 0.320
interleukin 12 secretion GO:0072610 3 0.317
negative regulation of phosphorus metabolic process GO:0010563 184 0.314
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.312
cation transport GO:0006812 399 0.311
myeloid leukocyte activation GO:0002274 83 0.306
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.305
innate immune response activating signal transduction GO:0002758 50 0.305
interferon gamma production GO:0032609 67 0.302
response to lipopolysaccharide GO:0032496 128 0.301
epithelial cell proliferation GO:0050673 174 0.301
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.301
eosinophil mediated immunity GO:0002447 1 0.299
cellular nitrogen compound catabolic process GO:0044270 280 0.298
regulation of apoptotic signaling pathway GO:2001233 197 0.291
leukocyte proliferation GO:0070661 172 0.290
positive regulation of adaptive immune response GO:0002821 61 0.287
actin cytoskeleton organization GO:0030036 220 0.284
lymphocyte mediated immunity GO:0002449 139 0.282
regulation of type 2 immune response GO:0002828 18 0.280
regulation of hematopoietic stem cell migration GO:2000471 1 0.278
regulation of cellular amine metabolic process GO:0033238 20 0.276
myeloid cell activation involved in immune response GO:0002275 34 0.275
negative regulation of leukocyte mediated immunity GO:0002704 29 0.274
negative regulation of eosinophil degranulation GO:0043310 1 0.270
negative regulation of leukocyte differentiation GO:1902106 51 0.266
cytokine production GO:0001816 319 0.264
endodermal cell fate specification GO:0001714 4 0.262
dna metabolic process GO:0006259 303 0.258
innate immune response GO:0045087 157 0.258
heart contraction GO:0060047 93 0.254
multicellular organismal signaling GO:0035637 91 0.251
chemokine mediated signaling pathway GO:0070098 17 0.246
regulation of acute inflammatory response GO:0002673 27 0.244
cellular amine metabolic process GO:0044106 44 0.242
morphogenesis of a branching epithelium GO:0061138 193 0.238
positive regulation of cell development GO:0010720 237 0.236
Zebrafish
divalent metal ion transport GO:0070838 172 0.231
cell migration involved in gastrulation GO:0042074 13 0.230
regulation of membrane potential GO:0042391 192 0.228
cerebral cortex development GO:0021987 86 0.227
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.226
digestive system development GO:0055123 200 0.226
regulation of t cell differentiation GO:0045580 83 0.225
inflammatory response to antigenic stimulus GO:0002437 30 0.225
regulation of ion homeostasis GO:2000021 64 0.225
positive regulation of alpha beta t cell activation GO:0046635 39 0.225
muscle contraction GO:0006936 101 0.223
isotype switching GO:0045190 36 0.222
leukocyte degranulation GO:0043299 27 0.221
t cell activation GO:0042110 289 0.221
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.220
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.219
placenta development GO:0001890 140 0.215
glycoprotein biosynthetic process GO:0009101 89 0.214
neuron projection guidance GO:0097485 141 0.214
t helper cell differentiation GO:0042093 28 0.213
carbohydrate derivative biosynthetic process GO:1901137 183 0.213
cytokine mediated signaling pathway GO:0019221 115 0.212
cytokine secretion GO:0050663 72 0.208
heterocycle catabolic process GO:0046700 280 0.208
regulation of multi organism process GO:0043900 111 0.207
regulation of leukocyte degranulation GO:0043300 20 0.205
negative regulation of phosphorylation GO:0042326 166 0.205
calcium ion transport GO:0006816 159 0.203
mature dendritic cell differentiation GO:0097029 3 0.202
type 2 immune response GO:0042092 23 0.200
exocytosis GO:0006887 121 0.199
erythrocyte differentiation GO:0030218 88 0.197
release of sequestered calcium ion into cytosol GO:0051209 42 0.197
cellular amino acid metabolic process GO:0006520 103 0.196
cellular response to molecule of bacterial origin GO:0071219 83 0.194
positive regulation of lymphocyte proliferation GO:0050671 70 0.194
sequestering of metal ion GO:0051238 19 0.193
ribonucleoside metabolic process GO:0009119 245 0.193
sequestering of calcium ion GO:0051208 18 0.193
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.192
single organism cell adhesion GO:0098602 156 0.191
ameboidal type cell migration GO:0001667 128 0.190
regulation of b cell activation GO:0050864 81 0.187
immune complex clearance by monocytes and macrophages GO:0002436 2 0.187
dna recombination GO:0006310 92 0.186
t cell differentiation involved in immune response GO:0002292 30 0.185
neuronal action potential GO:0019228 54 0.184
hematopoietic stem cell migration GO:0035701 1 0.182
g protein coupled receptor signaling pathway GO:0007186 243 0.179
regulation of establishment of protein localization GO:0070201 181 0.178
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.178
regulated secretory pathway GO:0045055 32 0.177
membrane organization GO:0061024 245 0.177
Worm
regulation of t cell proliferation GO:0042129 92 0.175
glycoprotein metabolic process GO:0009100 116 0.174
cytosolic calcium ion transport GO:0060401 48 0.172
regulation of hypersensitivity GO:0002883 10 0.171
heart process GO:0003015 94 0.171
cellular response to lipid GO:0071396 145 0.170
gland development GO:0048732 330 0.169
action potential GO:0001508 78 0.167
positive regulation of leukocyte proliferation GO:0070665 73 0.167
positive regulation of interleukin 12 production GO:0032735 21 0.166
response to organic cyclic compound GO:0014070 198 0.166
Fly
regulation of b cell proliferation GO:0030888 39 0.166
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.165
alpha beta t cell activation involved in immune response GO:0002287 31 0.164
organelle assembly GO:0070925 177 0.163
positive regulation of protein modification process GO:0031401 299 0.162
glycosyl compound catabolic process GO:1901658 206 0.162
granulocyte chemotaxis GO:0071621 39 0.161
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.161
dendritic cell differentiation GO:0097028 26 0.161
regulation of neuron differentiation GO:0045664 281 0.159
Zebrafish
regulation of monocyte chemotaxis GO:0090025 3 0.159
oligodendrocyte differentiation GO:0048709 53 0.157
regulation of cellular amino acid metabolic process GO:0006521 5 0.155
regulation of homeostatic process GO:0032844 182 0.154
respiratory system development GO:0060541 190 0.154
Fly
positive regulation of innate immune response GO:0045089 80 0.154
extrinsic apoptotic signaling pathway GO:0097191 126 0.153
protein secretion GO:0009306 111 0.150
lymph node development GO:0048535 18 0.149
granulocyte activation GO:0036230 10 0.148
regulation of chromatin modification GO:1903308 57 0.147
negative regulation of protein phosphorylation GO:0001933 126 0.147
calcium ion homeostasis GO:0055074 127 0.147
t cell activation involved in immune response GO:0002286 43 0.146
macrophage activation GO:0042116 27 0.144
negative regulation of macrophage apoptotic process GO:2000110 3 0.144
ribonucleotide metabolic process GO:0009259 291 0.144
blood vessel morphogenesis GO:0048514 285 0.142
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.141
myeloid cell homeostasis GO:0002262 114 0.140
signal transduction in absence of ligand GO:0038034 55 0.140
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.140
defense response to other organism GO:0098542 197 0.140
cardiac muscle contraction GO:0060048 32 0.138
ensheathment of neurons GO:0007272 76 0.137
regulation of cytokine biosynthetic process GO:0042035 59 0.136
positive regulation of monocyte chemotaxis GO:0090026 2 0.136
intracellular receptor signaling pathway GO:0030522 74 0.134
negative regulation of b cell proliferation GO:0030889 13 0.133
negative regulation of vasculature development GO:1901343 26 0.133
immunoglobulin mediated immune response GO:0016064 69 0.133
divalent inorganic cation homeostasis GO:0072507 138 0.133
axonogenesis GO:0007409 274 0.132
pallium development GO:0021543 120 0.131
regulation of alpha beta t cell proliferation GO:0046640 18 0.131
b cell proliferation GO:0042100 53 0.131
transmission of nerve impulse GO:0019226 76 0.130
divalent inorganic cation transport GO:0072511 178 0.129
regulation of organelle organization GO:0033043 289 0.128
amine metabolic process GO:0009308 45 0.127
positive regulation of nervous system development GO:0051962 221 0.126
Zebrafish
germinal center formation GO:0002467 16 0.126
neuron migration GO:0001764 122 0.125
positive regulation of cytokine biosynthetic process GO:0042108 40 0.124
cellular response to cytokine stimulus GO:0071345 189 0.124
regulation of interleukin 2 production GO:0032663 28 0.124
regulation of interleukin 12 production GO:0032655 30 0.123
regulation of cytokine secretion GO:0050707 61 0.123
myeloid leukocyte differentiation GO:0002573 119 0.123
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.122
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.121
acute inflammatory response to antigenic stimulus GO:0002438 12 0.121
neutrophil migration GO:1990266 37 0.121
rho protein signal transduction GO:0007266 32 0.120
negative regulation of type 2 immune response GO:0002829 8 0.120
camera type eye development GO:0043010 266 0.120
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.118
regulation of vasculature development GO:1901342 88 0.117
maintenance of location GO:0051235 89 0.116
t helper 1 type immune response GO:0042088 25 0.114
ribonucleoside catabolic process GO:0042454 206 0.114
somatic diversification of immunoglobulins GO:0016445 43 0.114
positive regulation of cytokine production GO:0001819 174 0.113
negative regulation of apoptotic signaling pathway GO:2001234 104 0.112
leukocyte migration GO:0050900 124 0.111
digestive tract development GO:0048565 190 0.110
small gtpase mediated signal transduction GO:0007264 97 0.110
hypersensitivity GO:0002524 10 0.109
positive regulation of glial cell differentiation GO:0045687 21 0.108
glycosyl compound metabolic process GO:1901657 246 0.107
organic cyclic compound catabolic process GO:1901361 295 0.107
nucleoside metabolic process GO:0009116 246 0.107
regulation of gliogenesis GO:0014013 50 0.106
transmembrane transport GO:0055085 412 0.105
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.105
embryonic organ morphogenesis GO:0048562 276 0.104
Zebrafish
regulation of alpha beta t cell differentiation GO:0046637 35 0.104
cell recognition GO:0008037 83 0.103
calcium ion transport into cytosol GO:0060402 48 0.103
regulation of neuron projection development GO:0010975 169 0.103
gastrulation GO:0007369 116 0.103
calcium mediated signaling GO:0019722 46 0.102
purine nucleotide catabolic process GO:0006195 211 0.100
regulation of t helper 1 type immune response GO:0002825 17 0.100
negative regulation of defense response GO:0031348 77 0.099
nucleoside catabolic process GO:0009164 206 0.099
regulation of rho protein signal transduction GO:0035023 71 0.099
negative regulation of b cell activation GO:0050869 27 0.098
myeloid cell apoptotic process GO:0033028 22 0.097
cellular divalent inorganic cation homeostasis GO:0072503 127 0.096
regulation of protein transport GO:0051223 163 0.096
regulation of regulated secretory pathway GO:1903305 20 0.096
interspecies interaction between organisms GO:0044419 83 0.095
chemotaxis GO:0006935 247 0.094
negative regulation of cellular amine metabolic process GO:0033239 1 0.093
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.093
purine containing compound catabolic process GO:0072523 213 0.092
regulation of lymphocyte differentiation GO:0045619 107 0.091
cytokine metabolic process GO:0042107 71 0.091
motor neuron axon guidance GO:0008045 26 0.091
positive regulation of leukocyte mediated immunity GO:0002705 70 0.090
granulocyte migration GO:0097530 43 0.090
cytoplasmic transport GO:0016482 234 0.088
lung development GO:0030324 164 0.088
negative regulation of phosphate metabolic process GO:0045936 184 0.088
negative regulation of innate immune response GO:0045824 17 0.088
negative regulation of blood vessel morphogenesis GO:2000181 25 0.087
regulation of t cell receptor signaling pathway GO:0050856 21 0.087
response to radiation GO:0009314 165 0.086
reactive oxygen species biosynthetic process GO:1903409 8 0.086
cytokine biosynthetic process GO:0042089 68 0.086
regulation of reactive oxygen species metabolic process GO:2000377 40 0.085
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.085
somatic diversification of immune receptors GO:0002200 53 0.085
muscle system process GO:0003012 141 0.085
regulation of exocytosis GO:0017157 61 0.085
positive regulation of t cell activation GO:0050870 101 0.085
negative regulation of immune system process GO:0002683 209 0.084
aromatic compound catabolic process GO:0019439 286 0.084
stem cell development GO:0048864 219 0.084
Zebrafish
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.083
cellular ion homeostasis GO:0006873 165 0.083
immunoglobulin production GO:0002377 73 0.083
negative regulation of protein modification process GO:0031400 163 0.083
regionalization GO:0003002 337 0.083
regulation of mapk cascade GO:0043408 248 0.082
cellular calcium ion homeostasis GO:0006874 119 0.082
negative regulation of inflammatory response GO:0050728 61 0.082
regulation of interferon gamma production GO:0032649 57 0.081
purine nucleoside triphosphate catabolic process GO:0009146 203 0.081
nucleotide catabolic process GO:0009166 217 0.081
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.081
ribose phosphate metabolic process GO:0019693 291 0.080
negative regulation of angiogenesis GO:0016525 25 0.080
cellular metal ion homeostasis GO:0006875 151 0.079
ras protein signal transduction GO:0007265 77 0.079
regulation of epithelial cell proliferation GO:0050678 141 0.079
interleukin 2 production GO:0032623 33 0.079
regulation of cell migration GO:0030334 219 0.079
Worm
regulation of protein localization GO:0032880 231 0.078
vascular endothelial growth factor production GO:0010573 13 0.078
negative thymic t cell selection GO:0045060 12 0.077
production of molecular mediator of immune response GO:0002440 103 0.077
regulation of chromosome organization GO:0033044 83 0.077
regulation of gtp catabolic process GO:0033124 113 0.076
developmental growth involved in morphogenesis GO:0060560 138 0.076
sensory organ morphogenesis GO:0090596 242 0.076
circulatory system process GO:0003013 197 0.076
cellular ketone metabolic process GO:0042180 84 0.076
negative regulation of t cell activation GO:0050868 65 0.076
nucleoside phosphate catabolic process GO:1901292 222 0.075
renal system development GO:0072001 225 0.074
regulation of lymphocyte mediated immunity GO:0002706 84 0.074
regulation of rho gtpase activity GO:0032319 58 0.073
peptidyl serine phosphorylation GO:0018105 74 0.073
erk1 and erk2 cascade GO:0070371 77 0.072
cytosolic calcium ion homeostasis GO:0051480 70 0.072
sensory perception GO:0007600 245 0.072
detection of stimulus GO:0051606 84 0.071
angiogenesis GO:0001525 201 0.071
cellular defense response GO:0006968 6 0.071
somatic cell dna recombination GO:0016444 51 0.071
purine nucleoside metabolic process GO:0042278 241 0.071
b cell differentiation GO:0030183 78 0.071
positive regulation of interferon gamma production GO:0032729 39 0.071
b cell mediated immunity GO:0019724 71 0.070
positive regulation of angiogenesis GO:0045766 46 0.070
negative regulation of protein metabolic process GO:0051248 282 0.070
axon guidance GO:0007411 141 0.069
regulation of cellular ketone metabolic process GO:0010565 66 0.069
positive regulation of gliogenesis GO:0014015 27 0.069
regulation of leukocyte differentiation GO:1902105 159 0.069
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.069
lymphocyte homeostasis GO:0002260 64 0.069
striated muscle contraction GO:0006941 45 0.068
response to acid chemical GO:0001101 111 0.068
respiratory tube development GO:0030323 167 0.067
cd4 positive alpha beta t cell activation GO:0035710 45 0.067
regulation of interleukin 1 production GO:0032652 26 0.067
regulation of hydrolase activity GO:0051336 246 0.066
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.065
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.065
tumor necrosis factor production GO:0032640 50 0.065
t cell proliferation GO:0042098 120 0.064
activation of innate immune response GO:0002218 56 0.064
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.064
interleukin 1 beta secretion GO:0050702 16 0.064
negative regulation of regulated secretory pathway GO:1903306 7 0.064
chromatin modification GO:0016568 187 0.063
telencephalon development GO:0021537 186 0.063
regulation of angiogenesis GO:0045765 81 0.063
kidney development GO:0001822 213 0.063
myeloid cell differentiation GO:0030099 233 0.063
response to organonitrogen compound GO:0010243 246 0.062
striated muscle cell development GO:0055002 125 0.062
phagocytosis GO:0006909 66 0.062
Worm
regulation of vesicle mediated transport GO:0060627 139 0.062
muscle cell development GO:0055001 133 0.062
purine nucleotide metabolic process GO:0006163 302 0.062
muscle cell differentiation GO:0042692 261 0.061
Zebrafish
regulation of secretion by cell GO:1903530 249 0.060
positive regulation of cell migration GO:0030335 109 0.060
t cell costimulation GO:0031295 14 0.060
second messenger mediated signaling GO:0019932 73 0.060
multi multicellular organism process GO:0044706 109 0.059
tube formation GO:0035148 140 0.059
cell fate commitment GO:0045165 210 0.059
b cell activation GO:0042113 161 0.059
posttranscriptional regulation of gene expression GO:0010608 155 0.058
regulation of cellular component size GO:0032535 121 0.058
endodermal cell fate commitment GO:0001711 12 0.058
cell type specific apoptotic process GO:0097285 268 0.058
gliogenesis GO:0042063 141 0.058
axon ensheathment GO:0008366 76 0.057
negative regulation of exocytosis GO:0045920 12 0.057
protein catabolic process GO:0030163 221 0.057
response to molecule of fungal origin GO:0002238 4 0.057
sensory perception of pain GO:0019233 47 0.056
nitrogen compound transport GO:0071705 271 0.056
positive regulation of secretion GO:0051047 130 0.056
negative regulation of lymphocyte activation GO:0051250 91 0.055
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.055
epithelium migration GO:0090132 63 0.055
response to decreased oxygen levels GO:0036293 59 0.055
mapk cascade GO:0000165 281 0.054
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.054
germ cell development GO:0007281 185 0.054
leukocyte mediated cytotoxicity GO:0001909 62 0.054
positive regulation of interleukin 2 production GO:0032743 19 0.054
regulation of phospholipase c activity GO:1900274 3 0.053
tolerance induction GO:0002507 14 0.053
regulation of ras gtpase activity GO:0032318 88 0.053
humoral immune response GO:0006959 57 0.053
apoptotic signaling pathway GO:0097190 306 0.052
leukocyte apoptotic process GO:0071887 71 0.052
nucleoside triphosphate catabolic process GO:0009143 205 0.052
regulation of ras protein signal transduction GO:0046578 114 0.052
regulation of mrna stability GO:0043488 23 0.052
positive regulation of b cell proliferation GO:0030890 24 0.052
metal ion homeostasis GO:0055065 189 0.052
regulation of secretion GO:0051046 274 0.051
alpha beta t cell proliferation GO:0046633 21 0.051
ion transmembrane transport GO:0034220 361 0.051
t helper 2 cell differentiation GO:0045064 12 0.051
negative regulation of adaptive immune response GO:0002820 25 0.051
carbohydrate derivative catabolic process GO:1901136 231 0.051
regulation of oligodendrocyte differentiation GO:0048713 23 0.051
pyrimidine containing compound catabolic process GO:0072529 3 0.051
gtp catabolic process GO:0006184 143 0.050
positive regulation of neuron differentiation GO:0045666 141 0.050
Zebrafish
digestive tract morphogenesis GO:0048546 147 0.050
negative regulation of intracellular signal transduction GO:1902532 167 0.050
covalent chromatin modification GO:0016569 163 0.050
positive regulation of protein phosphorylation GO:0001934 242 0.050
endocardial cushion formation GO:0003272 13 0.050
nucleus accumbens development GO:0021768 1 0.049
ribonucleoside triphosphate catabolic process GO:0009203 199 0.049
toll like receptor signaling pathway GO:0002224 38 0.049
purine ribonucleotide metabolic process GO:0009150 290 0.049
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.049
telencephalon cell migration GO:0022029 55 0.049
regulation of transposition GO:0010528 2 0.048
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.048
cytokine production involved in immune response GO:0002367 34 0.048
cardiac muscle tissue development GO:0048738 130 0.048
endomembrane system organization GO:0010256 147 0.048
endocytosis GO:0006897 168 0.048
Worm
germ line stem cell division GO:0042078 2 0.048
cerebral cortex cell migration GO:0021795 44 0.047
negative regulation of cell proliferation GO:0008285 296 0.047
regulation of rna stability GO:0043487 26 0.046
negative regulation of t cell differentiation GO:0045581 23 0.046
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.046
negative regulation of cellular protein metabolic process GO:0032269 247 0.046
defense response to bacterium GO:0042742 119 0.046
locomotory behavior GO:0007626 195 0.046
cellular homeostasis GO:0019725 240 0.046
myeloid dendritic cell differentiation GO:0043011 16 0.046
cellular lipid metabolic process GO:0044255 323 0.046
purine ribonucleoside catabolic process GO:0046130 205 0.046
regulation of protein secretion GO:0050708 82 0.045
negative regulation of cell cycle phase transition GO:1901988 48 0.045
metanephros development GO:0001656 79 0.044
regulation of cell projection organization GO:0031344 206 0.044
urogenital system development GO:0001655 261 0.044
multicellular organism growth GO:0035264 161 0.044
Worm
hematopoietic progenitor cell differentiation GO:0002244 143 0.044
forebrain cell migration GO:0021885 58 0.044
leukocyte chemotaxis GO:0030595 69 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.044
purine ribonucleoside metabolic process GO:0046128 241 0.044
regulation of protein kinase activity GO:0045859 232 0.044
cation homeostasis GO:0055080 212 0.043
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.043
negative regulation of cytokine production GO:0001818 84 0.042
reactive nitrogen species metabolic process GO:2001057 0 0.042
negative regulation of cell cycle GO:0045786 123 0.042
purine ribonucleotide catabolic process GO:0009154 208 0.042
positive regulation of programmed cell death GO:0043068 218 0.042

Prdm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org