|
|
behavioral response to cocaine
|
GO:0048148 |
10 |
0.856
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.727
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.670
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.578
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.530
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.516
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.510
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.499
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.483
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.471
|
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.444
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.436
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.428
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.417
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.413
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.411
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.397
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.390
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.383
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.371
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.369
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.362
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.353
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.351
|
|
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.351
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.334
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.324
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.323
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.322
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.321
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.318
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.316
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.308
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.307
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.295
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.293
|
Human |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.292
|
Worm |
|
|
cognition
|
GO:0050890 |
149 |
0.283
|
Fly |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.271
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.263
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.260
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.258
|
Yeast |
|
|
cardiac muscle tissue growth
|
GO:0055017 |
37 |
0.254
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.249
|
|
|
|
response to cocaine
|
GO:0042220 |
14 |
0.247
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.237
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.230
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.227
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.225
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.225
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.224
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.219
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.218
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.211
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.206
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.205
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.204
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.204
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.203
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.202
|
Worm Fly |
|
|
amide transport
|
GO:0042886 |
138 |
0.200
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.199
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.199
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.198
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.198
|
|
|
|
regulation of cell growth involved in cardiac muscle cell development
|
GO:0061050 |
3 |
0.197
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.196
|
|
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
31 |
0.196
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.194
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.193
|
|
|
|
positive regulation of oocyte development
|
GO:0060282 |
4 |
0.191
|
Worm |
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.191
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.190
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.189
|
|
|
|
sarcomere organization
|
GO:0045214 |
24 |
0.189
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.189
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.187
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.186
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.185
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.185
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.183
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.180
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.179
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.177
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.176
|
|
|
|
physiological muscle hypertrophy
|
GO:0003298 |
3 |
0.176
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.176
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.174
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.170
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.168
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.168
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.165
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.165
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.162
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.161
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.160
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.160
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.159
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.159
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.153
|
Human |
|
|
nuclear import
|
GO:0051170 |
95 |
0.152
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.151
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.151
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.151
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.150
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.150
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.149
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.148
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.146
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.144
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.144
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.143
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
26 |
0.143
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.142
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.141
|
Fly |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.141
|
Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.141
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.140
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.140
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.140
|
Human |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.140
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.139
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.139
|
Worm Fly |
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.136
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.136
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.135
|
Human |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.134
|
|
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.134
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.132
|
|
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.132
|
Worm |
|
|
heart contraction
|
GO:0060047 |
93 |
0.132
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.129
|
|
|
|
cellular polysaccharide catabolic process
|
GO:0044247 |
5 |
0.129
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.129
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.129
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.129
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.128
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.128
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.128
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.127
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
12 |
0.126
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.126
|
Yeast |
|
|
oogenesis
|
GO:0048477 |
56 |
0.125
|
Worm Fly |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.122
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.121
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.120
|
Rat |
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.120
|
Worm Fly |
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.120
|
Rat |
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.119
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.118
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.115
|
Rat |
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
5 |
0.114
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.113
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.113
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.112
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.112
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.111
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.110
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.110
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.109
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
19 |
0.109
|
Worm |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.108
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.108
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.107
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.107
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.107
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.106
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.106
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.104
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.103
|
Fly |
|
|
glucose transport
|
GO:0015758 |
56 |
0.102
|
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.100
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.099
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.099
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.098
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.097
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.096
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.096
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.096
|
|
|
|
heart growth
|
GO:0060419 |
45 |
0.096
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.094
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.093
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.092
|
|
|
|
cellular response to temperature stimulus
|
GO:0071502 |
2 |
0.091
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.090
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.090
|
Human |
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.089
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.089
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.088
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.087
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.087
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.086
|
Human |
|
|
olfactory learning
|
GO:0008355 |
2 |
0.086
|
Fly |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.085
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.085
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.085
|
Human |
|
|
endocytosis
|
GO:0006897 |
168 |
0.084
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.084
|
|
|
|
regulation of long term synaptic potentiation
|
GO:1900271 |
4 |
0.083
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.082
|
|
|
|
sensitization
|
GO:0046960 |
2 |
0.082
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.082
|
|
|
|
insulin secretion involved in cellular response to glucose stimulus
|
GO:0035773 |
36 |
0.082
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.081
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.081
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.080
|
|
|
|
memory
|
GO:0007613 |
58 |
0.080
|
Fly |
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.079
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.078
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.078
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.077
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.077
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.076
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.076
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.076
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.076
|
Worm |
|
|
organ growth
|
GO:0035265 |
117 |
0.075
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.075
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.074
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.074
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.074
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.074
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.073
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.073
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.073
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.073
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.072
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.072
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.072
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.071
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.071
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.071
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.070
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.070
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.069
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.069
|
Human |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.069
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.069
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.068
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.067
|
Rat |
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.067
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.067
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.067
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.066
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.066
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.066
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.066
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
34 |
0.065
|
Rat |
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.065
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.065
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.065
|
Rat |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.065
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.064
|
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.063
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.063
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.063
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.063
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.063
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.063
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.062
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.062
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.062
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.061
|
|
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.061
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
39 |
0.060
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
8 |
0.060
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.060
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.060
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.059
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.059
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.058
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.058
|
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.058
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.058
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.057
|
Yeast |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.057
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.057
|
|
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
30 |
0.056
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.056
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.056
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.056
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.056
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.056
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.056
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.055
|
Human |
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.055
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.055
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.055
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
16 |
0.055
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.055
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.055
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.054
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.054
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.054
|
|
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.053
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.053
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.053
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.053
|
|
|
|
grooming behavior
|
GO:0007625 |
16 |
0.052
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.052
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.052
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.052
|
Fly |
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.052
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
18 |
0.051
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.051
|
Human |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.051
|
Human |
|
|
cellular carbohydrate catabolic process
|
GO:0044275 |
15 |
0.050
|
|
|
|
negative regulation of camp dependent protein kinase activity
|
GO:2000480 |
1 |
0.050
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.050
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.050
|
|
|
|
positive regulation of membrane potential
|
GO:0045838 |
15 |
0.050
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.050
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.050
|
|
|
|
response to amine
|
GO:0014075 |
16 |
0.050
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.050
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.049
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.049
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.049
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.049
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.048
|
Human |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.048
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.048
|
|
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.048
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.048
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.048
|
Worm |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.048
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.047
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.047
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.047
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.047
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.047
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.047
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.047
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.046
|
Worm |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.046
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.046
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.046
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.046
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.046
|
|
|
|
protein localization to cytoskeleton
|
GO:0044380 |
9 |
0.045
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.045
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.045
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.045
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.045
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.045
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.044
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.044
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.044
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.044
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.044
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.044
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.044
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.043
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.043
|
|
|
|
cellular response to hexose stimulus
|
GO:0071331 |
47 |
0.043
|
Human |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.043
|
|
|
|
mating
|
GO:0007618 |
27 |
0.043
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.042
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.042
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.042
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.042
|
Fly |
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.042
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.042
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.041
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.041
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.041
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.041
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.041
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
14 |
0.041
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.041
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.041
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.040
|
|
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
8 |
0.040
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.040
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.040
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.040
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.040
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.040
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.040
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.040
|
|
|
|
regulation of muscle hypertrophy
|
GO:0014743 |
13 |
0.039
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.039
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.039
|
Fly |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.039
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.038
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.038
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.038
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.038
|
|
|
|
regulation of carbohydrate catabolic process
|
GO:0043470 |
12 |
0.038
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.038
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.038
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.038
|
|
|
|
cellular response to ethanol
|
GO:0071361 |
3 |
0.038
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.038
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.037
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.037
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.037
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.037
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.037
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.037
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.037
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.037
|
Mouse |
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.037
|
|
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
23 |
0.037
|
Worm |
|
|
pyruvate metabolic process
|
GO:0006090 |
28 |
0.036
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.036
|
|
|
|
gastrin induced gastric acid secretion
|
GO:0001698 |
1 |
0.036
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.036
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.036
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.036
|
|
|
|
regulation of muscle adaptation
|
GO:0043502 |
31 |
0.036
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.036
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.036
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.036
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.036
|
Mouse |
|
|
positive regulation of the force of heart contraction by chemical signal
|
GO:0003099 |
3 |
0.035
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.035
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.035
|
|
|
|
physiological cardiac muscle hypertrophy
|
GO:0003301 |
3 |
0.035
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.035
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.035
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.035
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.035
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.035
|
|
|
|
polysaccharide catabolic process
|
GO:0000272 |
5 |
0.035
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.035
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.034
|
|
|
|
phasic smooth muscle contraction
|
GO:0014821 |
8 |
0.034
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.034
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.034
|
Fly |
|
|
glucan catabolic process
|
GO:0009251 |
5 |
0.034
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.034
|
Fly |
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.034
|
|
|
|
regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061178 |
31 |
0.034
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
1 |
0.034
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.034
|
|
|
|
establishment of melanosome localization
|
GO:0032401 |
11 |
0.033
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.033
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.033
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.033
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.033
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.033
|
Rat |
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.032
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.032
|
|
|
|
striatum development
|
GO:0021756 |
14 |
0.032
|
|
|
|
positive regulation of killing of cells of other organism
|
GO:0051712 |
3 |
0.032
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.032
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.032
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.032
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.031
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.031
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.031
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.031
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.031
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.031
|
|
|
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
12 |
0.031
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.031
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.031
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.031
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.030
|
|
|
|
translation
|
GO:0006412 |
93 |
0.030
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.030
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.030
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.030
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.030
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.030
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.030
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.030
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.029
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.029
|
Fly |
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
7 |
0.029
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.029
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.029
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.029
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.029
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.029
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.029
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.029
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.029
|
Worm |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.028
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.028
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.028
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.028
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.028
|
|
|
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
GO:0045743 |
3 |
0.028
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.028
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.028
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.028
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.028
|
|
