|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.975
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.953
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.948
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.944
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.941
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.938
|
Human |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.936
|
Mouse |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.935
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.935
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.928
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.926
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.924
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.903
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.889
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.888
|
Mouse |
|
|
hemostasis
|
GO:0007599 |
78 |
0.886
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.878
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.871
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.864
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.861
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.854
|
Mouse |
|
|
olfactory learning
|
GO:0008355 |
2 |
0.852
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.847
|
Human Mouse |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.844
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.842
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.835
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.826
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.823
|
Mouse |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.823
|
Human Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.819
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.814
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
1 |
0.809
|
Mouse |
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.805
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.801
|
Mouse |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.799
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.796
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.795
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.794
|
Mouse |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.793
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.791
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.789
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.783
|
Mouse Worm |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.783
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.775
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.773
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.772
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.771
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.767
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.762
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.761
|
Rat |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.757
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.756
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.755
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.754
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.753
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.752
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.749
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.746
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.745
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.730
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.713
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.713
|
Mouse |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.711
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.710
|
Mouse |
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.710
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.706
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.702
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.700
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.694
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.694
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.692
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.690
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.684
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.677
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.671
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.661
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.659
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.656
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.656
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.653
|
Mouse |
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.653
|
Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.653
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.652
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
4 |
0.646
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.645
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.639
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.633
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.632
|
Mouse |
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.628
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.621
|
Worm |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.621
|
Mouse |
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.620
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.618
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.617
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.615
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.615
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.615
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.609
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.605
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.596
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.595
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.594
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.593
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.591
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.589
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.588
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.587
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.586
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.580
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.575
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.574
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.571
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.565
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.564
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.563
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.556
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.554
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.553
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.552
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.551
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.549
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.546
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.546
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.542
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.538
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.538
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.537
|
|
|
|
positive regulation of macrophage derived foam cell differentiation
|
GO:0010744 |
4 |
0.536
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.536
|
Mouse |
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.535
|
Mouse |
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.531
|
Human Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.531
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.527
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.524
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.521
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.521
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.518
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.517
|
Rat |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.514
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.513
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.511
|
Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.511
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.510
|
Mouse |
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.501
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.496
|
Fly |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.496
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.495
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.492
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.492
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.490
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.486
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.485
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.484
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.481
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.477
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.476
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.475
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.475
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.474
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.471
|
Mouse |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.470
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.469
|
Human |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.469
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.463
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.460
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.459
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.458
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.458
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.457
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.455
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.454
|
|
|
|
learning
|
GO:0007612 |
98 |
0.453
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.449
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.448
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.448
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.447
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.446
|
Mouse |
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.446
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.445
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.445
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.445
|
Mouse |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.445
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.443
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.440
|
Mouse |
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.440
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.439
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.435
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.432
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.431
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.426
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.425
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.425
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.423
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.418
|
Fly |
|
|
cellular response to light stimulus
|
GO:0071482 |
19 |
0.418
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.418
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.418
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.417
|
Mouse |
|
|
phototransduction
|
GO:0007602 |
17 |
0.416
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.415
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.415
|
|
|
|
cellular response to cadmium ion
|
GO:0071276 |
3 |
0.412
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.412
|
Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.402
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.396
|
Mouse |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.393
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.392
|
Human |
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.392
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.391
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.388
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.385
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
200 |
0.383
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.381
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.379
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.377
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.375
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.375
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.374
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.374
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.373
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.369
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.360
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.359
|
|
|
|
response to morphine
|
GO:0043278 |
9 |
0.359
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.358
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.358
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.358
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.357
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.356
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.353
|
Human Mouse |
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.353
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.353
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.350
|
Mouse |
|
|
positive regulation of interleukin 10 secretion
|
GO:2001181 |
1 |
0.350
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.350
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.349
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.347
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.347
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.347
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.346
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.345
|
|
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
2 |
0.342
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.341
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.340
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.340
|
Human |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.340
|
Human |
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.338
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.338
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.336
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.336
|
|
|
|
sarcomere organization
|
GO:0045214 |
24 |
0.335
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.335
|
Worm |
|
|
cytokine production
|
GO:0001816 |
319 |
0.334
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.332
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.331
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.331
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.330
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.328
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.327
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.326
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.325
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.324
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.322
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.321
|
|
|
|
dense core granule biogenesis
|
GO:0061110 |
1 |
0.321
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.317
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.316
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.316
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.315
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.315
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.315
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.314
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.313
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.312
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.310
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.306
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.306
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.305
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.303
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.302
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
2 |
0.301
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.301
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.300
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.299
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.298
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.297
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.294
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.291
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.290
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.289
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.288
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.288
|
Mouse |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.288
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.286
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.286
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.285
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.284
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.282
|
|
|
|
regulation of ral gtpase activity
|
GO:0032315 |
4 |
0.281
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.280
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.279
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.278
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.276
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.273
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.273
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.272
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.271
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.271
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.270
|
Mouse |
|
|
protein localization to cell junction
|
GO:1902414 |
3 |
0.268
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.268
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.267
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.266
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.265
|
|
|
|
macrophage derived foam cell differentiation
|
GO:0010742 |
6 |
0.263
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.263
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.262
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.261
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.260
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
176 |
0.260
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.260
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.259
|
Mouse |
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.257
|
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.256
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.255
|
Fly |
|
|
regulation of membrane depolarization
|
GO:0003254 |
11 |
0.254
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.253
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.253
|
|
|
|
positive regulation of protein autophosphorylation
|
GO:0031954 |
4 |
0.253
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.252
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.251
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.250
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.250
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.247
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.246
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.245
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.244
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.243
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.243
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.243
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.241
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.241
|
|
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
24 |
0.239
|
Mouse |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.237
|
Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.235
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.235
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.235
|
Mouse Fly |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.235
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.233
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.232
|
Human Mouse |
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.230
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.230
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.229
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.229
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.228
|
Worm |
|
|
progesterone receptor signaling pathway
|
GO:0050847 |
2 |
0.228
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.227
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.225
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.225
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.225
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.225
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.222
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.222
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.221
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
9 |
0.221
|
Mouse |
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.219
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.218
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.217
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.216
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.215
|
Mouse |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.215
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.213
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.213
|
Worm |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.212
|
Mouse |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.212
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.212
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.211
|
|
|
|
positive regulation of lipid catabolic process
|
GO:0050996 |
6 |
0.208
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.207
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.207
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.206
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.206
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.206
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.206
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.205
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.204
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.204
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.203
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.203
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.202
|
Mouse |
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.202
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.202
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.201
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.200
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.196
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.196
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.195
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.194
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.194
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.192
|
|
|
|
ral protein signal transduction
|
GO:0032484 |
2 |
0.191
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.190
|
Fly |
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.189
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.189
|
|
|
|
osmosensory signaling pathway
|
GO:0007231 |
1 |
0.188
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.184
|
Mouse |
|
|
cellular response to oxygen levels
|
GO:0071453 |
20 |
0.184
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.183
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.182
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.182
|
Mouse |
|
|
gonad development
|
GO:0008406 |
141 |
0.181
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.181
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.181
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.180
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.180
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.180
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.178
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.178
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.178
|
Mouse |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.178
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.178
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.176
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.175
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.175
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.175
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.175
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.174
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.174
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.173
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.172
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.172
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.171
|
|
|
|
regulation of long term synaptic depression
|
GO:1900452 |
3 |
0.171
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.171
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.171
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.170
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.169
|
Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.169
|
Human |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.169
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.169
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
32 |
0.168
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
15 |
0.167
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.167
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.167
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.166
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.166
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.164
|
|
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.164
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.163
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.162
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.162
|
Worm |
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.162
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.162
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.161
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.161
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.161
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.161
|
|
|
|
cellular response to ethanol
|
GO:0071361 |
3 |
0.160
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.160
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.159
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.157
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.156
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.156
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.156
|
Worm |
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.155
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.155
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.154
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.154
|
|
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.153
|
|
|
|
response to isoquinoline alkaloid
|
GO:0014072 |
9 |
0.153
|
|
|
|
positive regulation of interleukin 5 secretion
|
GO:2000664 |
1 |
0.152
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.152
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.151
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.151
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.151
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.151
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.150
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.150
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.150
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.149
|
Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.149
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
27 |
0.148
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.148
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
4 |
0.147
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.147
|
|
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.147
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.147
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.146
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.146
|
|
