Mus musculus

78 known processes

Prlr

prolactin receptor

(Aliases: Prlr-rs1,Pr-1,Pr-3,AI987712)

Prlr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate metabolic process GO:0005975 230 0.986
response to peptide hormone GO:0043434 127 0.981
Mouse
steroid metabolic process GO:0008202 119 0.980
cellular lipid metabolic process GO:0044255 323 0.972
Mouse
monosaccharide metabolic process GO:0005996 106 0.970
multicellular organism growth GO:0035264 161 0.969
Mouse
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.968
regulation of hormone levels GO:0010817 211 0.955
regulation of carbohydrate biosynthetic process GO:0043255 40 0.953
monocarboxylic acid metabolic process GO:0032787 191 0.933
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.931
oxidation reduction process GO:0055114 342 0.919
hormone metabolic process GO:0042445 86 0.910
response to peptide GO:1901652 136 0.902
Mouse
myeloid cell differentiation GO:0030099 233 0.890
regulation of glucose metabolic process GO:0010906 60 0.888
lipid biosynthetic process GO:0008610 179 0.878
regulation of carbohydrate metabolic process GO:0006109 75 0.871
rhythmic process GO:0048511 174 0.863
carbohydrate biosynthetic process GO:0016051 74 0.858
regulation of lipid metabolic process GO:0019216 118 0.855
cellular response to hormone stimulus GO:0032870 150 0.850
progesterone metabolic process GO:0042448 4 0.841
response to organic cyclic compound GO:0014070 198 0.838
regulation of steroid biosynthetic process GO:0050810 26 0.837
gland development GO:0048732 330 0.833
response to organonitrogen compound GO:0010243 246 0.832
Mouse
fatty acid metabolic process GO:0006631 121 0.832
Mouse
small molecule biosynthetic process GO:0044283 132 0.831
cellular response to peptide hormone stimulus GO:0071375 92 0.829
Mouse
ovulation cycle GO:0042698 59 0.815
hormone mediated signaling pathway GO:0009755 23 0.792
regulation of steroid metabolic process GO:0019218 39 0.786
hexose metabolic process GO:0019318 98 0.780
response to phenylpropanoid GO:0080184 22 0.775
alpha amino acid metabolic process GO:1901605 59 0.765
Mouse
regulation of mast cell differentiation GO:0060375 3 0.763
response to insulin GO:0032868 100 0.757
acylglycerol metabolic process GO:0006639 55 0.756
neutral lipid metabolic process GO:0006638 57 0.750
regulation of fatty acid oxidation GO:0046320 10 0.749
response to alcohol GO:0097305 48 0.733
glucose metabolic process GO:0006006 92 0.731
negative regulation of triglyceride metabolic process GO:0090209 4 0.721
response to testosterone GO:0033574 3 0.721
peptide secretion GO:0002790 114 0.719
cellular carbohydrate metabolic process GO:0044262 119 0.718
stem cell maintenance GO:0019827 130 0.714
cellular amine metabolic process GO:0044106 44 0.711
response to extracellular stimulus GO:0009991 127 0.711
female sex differentiation GO:0046660 84 0.710
sulfur compound metabolic process GO:0006790 100 0.685
Mouse
steroid biosynthetic process GO:0006694 47 0.684
taurine metabolic process GO:0019530 4 0.662
Mouse
positive regulation of apoptotic process GO:0043065 217 0.662
female gonad development GO:0008585 71 0.656
glycerolipid metabolic process GO:0046486 122 0.651
lipid homeostasis GO:0055088 63 0.645
cellular response to peptide GO:1901653 92 0.632
Mouse
monosaccharide biosynthetic process GO:0046364 44 0.629
regulation of triglyceride metabolic process GO:0090207 17 0.626
cellular response to gonadotropin stimulus GO:0071371 4 0.622
regulation of lipid biosynthetic process GO:0046890 54 0.620
regulation of steroid hormone biosynthetic process GO:0090030 4 0.614
kidney development GO:0001822 213 0.605
luteinization GO:0001553 8 0.598
development of primary sexual characteristics GO:0045137 143 0.585
intracellular receptor signaling pathway GO:0030522 74 0.580
erythrocyte differentiation GO:0030218 88 0.576
development of primary female sexual characteristics GO:0046545 73 0.572
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.567
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.566
Human Mouse
regulation of gluconeogenesis GO:0006111 30 0.566
wnt signaling pathway GO:0016055 188 0.566
gluconeogenesis GO:0006094 39 0.564
purine ribonucleotide biosynthetic process GO:0009152 59 0.564
organic acid catabolic process GO:0016054 51 0.561
lipid localization GO:0010876 126 0.559
cellular response to organonitrogen compound GO:0071417 145 0.557
Mouse
regulation of androgen receptor signaling pathway GO:0060765 3 0.554
regulation of leukocyte differentiation GO:1902105 159 0.552
regulation of cellular catabolic process GO:0031329 242 0.535
alcohol metabolic process GO:0006066 116 0.534
dicarboxylic acid metabolic process GO:0043648 18 0.534
Mouse
terpenoid metabolic process GO:0006721 25 0.528
response to nutrient levels GO:0031667 109 0.524
positive regulation of apoptotic signaling pathway GO:2001235 95 0.517
isoprenoid metabolic process GO:0006720 29 0.512
response to steroid hormone GO:0048545 56 0.512
lipid catabolic process GO:0016042 69 0.510
organic hydroxy compound metabolic process GO:1901615 203 0.508
organic hydroxy compound biosynthetic process GO:1901617 77 0.505
cellular lipid catabolic process GO:0044242 52 0.503
development of secondary male sexual characteristics GO:0046544 3 0.501
peptide transport GO:0015833 133 0.497
cellular ketone metabolic process GO:0042180 84 0.493
regulation of feeding behavior GO:0060259 3 0.490
regionalization GO:0003002 337 0.489
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.477
steroid hormone mediated signaling pathway GO:0043401 6 0.471
regulation of myeloid leukocyte differentiation GO:0002761 58 0.463
prostate gland development GO:0030850 48 0.456
monocarboxylic acid biosynthetic process GO:0072330 61 0.453
regulation of natural killer cell differentiation GO:0032823 11 0.449
synaptic transmission GO:0007268 329 0.445
response to xenobiotic stimulus GO:0009410 13 0.441
regulation of erythrocyte differentiation GO:0045646 23 0.441
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.441
cyclic purine nucleotide metabolic process GO:0052652 43 0.441
gonad development GO:0008406 141 0.439
negative regulation of peptide secretion GO:0002792 16 0.434
innate immune response GO:0045087 157 0.433
protein localization to organelle GO:0033365 185 0.432
g protein coupled receptor signaling pathway GO:0007186 243 0.430
regulation of hydrolase activity GO:0051336 246 0.424
prostate gland growth GO:0060736 13 0.419
triglyceride metabolic process GO:0006641 51 0.412
spermatogenesis exchange of chromosomal proteins GO:0035093 4 0.398
generation of precursor metabolites and energy GO:0006091 103 0.397
diterpenoid metabolic process GO:0016101 24 0.396
regulation of cellular ketone metabolic process GO:0010565 66 0.394
mammary gland epithelium development GO:0061180 65 0.394
cellular response to growth factor stimulus GO:0071363 197 0.392
regulation of hormone secretion GO:0046883 88 0.391
negative regulation of protein metabolic process GO:0051248 282 0.388
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.388
regulation of fatty acid metabolic process GO:0019217 28 0.385
carboxylic acid catabolic process GO:0046395 51 0.380
cholesterol homeostasis GO:0042632 44 0.379
feeding behavior GO:0007631 62 0.375
regulation of camp metabolic process GO:0030814 30 0.373
regulation of carbohydrate catabolic process GO:0043470 12 0.370
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.364
insulin secretion GO:0030073 89 0.361
cellular response to insulin stimulus GO:0032869 78 0.358
regulation of myeloid cell differentiation GO:0045637 96 0.357
germ cell development GO:0007281 185 0.357
cellular response to lipid GO:0071396 145 0.355
positive regulation of carbohydrate metabolic process GO:0045913 30 0.352
spermatogenesis GO:0007283 284 0.348
positive regulation of intracellular steroid hormone receptor signaling pathway GO:0033145 4 0.346
lipid storage GO:0019915 36 0.343
muscle cell differentiation GO:0042692 261 0.343
regulation of nucleotide biosynthetic process GO:0030808 34 0.332
regulation of secretion by cell GO:1903530 249 0.330
regulation of lymphocyte proliferation GO:0050670 117 0.329
fat soluble vitamin biosynthetic process GO:0042362 4 0.328
negative regulation of cell proliferation GO:0008285 296 0.328
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.326
urogenital system development GO:0001655 261 0.326
amide transport GO:0042886 138 0.323
glial cell differentiation GO:0010001 131 0.322
macromolecule catabolic process GO:0009057 281 0.322
positive regulation of programmed cell death GO:0043068 218 0.321
regulation of mast cell proliferation GO:0070666 4 0.311
male gamete generation GO:0048232 285 0.310
regulation of lipid transport GO:0032368 36 0.307
organ growth GO:0035265 117 0.303
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.298
regulation of fatty acid biosynthetic process GO:0042304 12 0.298
male sex differentiation GO:0046661 109 0.293
response to food GO:0032094 17 0.291
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.287
lactation GO:0007595 25 0.285
maintenance of location GO:0051235 89 0.283
positive regulation of hormone secretion GO:0046887 38 0.277
renal system development GO:0072001 225 0.275
pyruvate metabolic process GO:0006090 28 0.274
fatty acid catabolic process GO:0009062 25 0.273
regulation of cell cycle GO:0051726 281 0.270
regulation of neuron death GO:1901214 134 0.269
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.265
amine metabolic process GO:0009308 45 0.263
regulation of peptide secretion GO:0002791 77 0.260
positive regulation of fatty acid oxidation GO:0046321 4 0.259
lipid transport GO:0006869 98 0.259
negative regulation of peptide hormone secretion GO:0090278 16 0.258
digestive tract development GO:0048565 190 0.257
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.257
regulation of chromosome organization GO:0033044 83 0.255
positive regulation of cell death GO:0010942 224 0.254
small molecule catabolic process GO:0044282 71 0.254
neuron death GO:0070997 154 0.252
water homeostasis GO:0030104 27 0.248
regulation of endopeptidase activity GO:0052548 89 0.246
cyclic nucleotide biosynthetic process GO:0009190 44 0.246
regulation of secretion GO:0051046 274 0.245
sensory perception GO:0007600 245 0.245
protein kinase b signaling GO:0043491 74 0.244
stem cell development GO:0048864 219 0.243
glycoprotein metabolic process GO:0009100 116 0.241
calcitriol biosynthetic process from calciol GO:0036378 3 0.239
regulation of cell migration GO:0030334 219 0.238
leukocyte differentiation GO:0002521 342 0.238
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.235
negative regulation of insulin secretion GO:0046676 14 0.234
regulation of protein kinase activity GO:0045859 232 0.232
Human
negative regulation of lipid metabolic process GO:0045833 30 0.232
female gamete generation GO:0007292 74 0.231
cognition GO:0050890 149 0.227
cellular carbohydrate catabolic process GO:0044275 15 0.227
positive regulation of glucose metabolic process GO:0010907 21 0.226
hormone secretion GO:0046879 128 0.226
apoptotic signaling pathway GO:0097190 306 0.225
regulation of camp biosynthetic process GO:0030817 25 0.221
response to glucocorticoid GO:0051384 20 0.221
ovulation GO:0030728 15 0.221
hormone biosynthetic process GO:0042446 16 0.217
cellular alcohol biosynthetic process GO:0044108 3 0.215
epithelial tube morphogenesis GO:0060562 303 0.215
creatinine metabolic process GO:0046449 3 0.215
Mouse
hexose biosynthetic process GO:0019319 39 0.213
mammary gland morphogenesis GO:0060443 54 0.211
cellular polysaccharide metabolic process GO:0044264 38 0.210
carbohydrate derivative biosynthetic process GO:1901137 183 0.209
ribose phosphate biosynthetic process GO:0046390 59 0.206
negative regulation of cell cycle GO:0045786 123 0.206
antral ovarian follicle growth GO:0001547 5 0.203
dna metabolic process GO:0006259 303 0.203
regulation of leukocyte proliferation GO:0070663 121 0.203
establishment of protein localization to organelle GO:0072594 118 0.203
alpha amino acid catabolic process GO:1901606 18 0.202
nitrogen compound transport GO:0071705 271 0.202
glucose homeostasis GO:0042593 128 0.200
energy reserve metabolic process GO:0006112 39 0.199
vitamin d biosynthetic process GO:0042368 3 0.199
cellular response to organic cyclic compound GO:0071407 87 0.198
unsaturated fatty acid metabolic process GO:0033559 31 0.197
circulatory system process GO:0003013 197 0.195
protein processing GO:0016485 163 0.193
catecholamine uptake GO:0090493 4 0.192
asymmetric stem cell division GO:0098722 3 0.192
response to corticosteroid GO:0031960 20 0.192
canonical wnt signaling pathway GO:0060070 130 0.191
protein localization to nucleus GO:0034504 121 0.191
regulation of system process GO:0044057 200 0.190
response to growth factor GO:0070848 198 0.190
carbohydrate homeostasis GO:0033500 128 0.189
mitotic cell cycle GO:0000278 195 0.189
regulation of proteolysis GO:0030162 164 0.189
ovulation from ovarian follicle GO:0001542 9 0.188
regulation of intracellular transport GO:0032386 159 0.188
positive regulation of camp metabolic process GO:0030816 19 0.187
negative regulation of cell motility GO:2000146 61 0.187
regulation of peptidase activity GO:0052547 96 0.185
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.183
mammary gland duct morphogenesis GO:0060603 38 0.182
defense response to other organism GO:0098542 197 0.181
cell maturation GO:0048469 127 0.181
regulation of insulin receptor signaling pathway GO:0046626 21 0.181
fatty acid derivative metabolic process GO:1901568 33 0.180
neuropeptide signaling pathway GO:0007218 19 0.180
carboxylic acid biosynthetic process GO:0046394 86 0.179
sensory organ morphogenesis GO:0090596 242 0.179
regulation of canonical wnt signaling pathway GO:0060828 82 0.179
vitamin d3 metabolic process GO:0070640 3 0.178
regulation of wnt signaling pathway GO:0030111 123 0.178
organic acid biosynthetic process GO:0016053 86 0.177
drug catabolic process GO:0042737 2 0.177
negative regulation of carbohydrate metabolic process GO:0045912 19 0.177
ribose phosphate metabolic process GO:0019693 291 0.175
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.173
positive regulation of steroid hormone secretion GO:2000833 2 0.172
extrinsic apoptotic signaling pathway GO:0097191 126 0.172
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.169
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.169
succinate metabolic process GO:0006105 4 0.168
Mouse
mesonephros development GO:0001823 97 0.168
response to growth hormone GO:0060416 7 0.168
Mouse
positive regulation of transferase activity GO:0051347 167 0.167
Human
ureteric bud development GO:0001657 94 0.166
negative regulation of cellular catabolic process GO:0031330 47 0.166
cell type specific apoptotic process GO:0097285 268 0.166
positive regulation of smooth muscle cell migration GO:0014911 4 0.164
regulation of organ morphogenesis GO:2000027 144 0.164
positive regulation of gluconeogenesis GO:0045722 11 0.164
ovarian follicle development GO:0001541 40 0.164
transmembrane transport GO:0055085 412 0.164
homeostasis of number of cells GO:0048872 210 0.163
cellular chemical homeostasis GO:0055082 215 0.162
positive regulation of innate immune response GO:0045089 80 0.162
prostate gland morphogenesis GO:0060512 32 0.162
response to decreased oxygen levels GO:0036293 59 0.161
acetate ester metabolic process GO:1900619 3 0.161
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.159
sterol homeostasis GO:0055092 45 0.158
negative regulation of apoptotic signaling pathway GO:2001234 104 0.156
purine ribonucleotide metabolic process GO:0009150 290 0.155
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.154
regulation of jak stat cascade GO:0046425 34 0.153
angiogenesis GO:0001525 201 0.153
regulation of organelle organization GO:0033043 289 0.153
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.151
carbohydrate catabolic process GO:0016052 32 0.151
cell growth GO:0016049 130 0.151
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.150
spermatid differentiation GO:0048515 115 0.149
protein maturation GO:0051604 176 0.148
maternal process involved in female pregnancy GO:0060135 32 0.147
cellular response to steroid hormone stimulus GO:0071383 33 0.147
epithelial cell proliferation GO:0050673 174 0.147
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.147
energy derivation by oxidation of organic compounds GO:0015980 77 0.146
cell division GO:0051301 120 0.146
cellular response to nutrient levels GO:0031669 64 0.146
protein import GO:0017038 101 0.146
negative regulation of molecular function GO:0044092 258 0.145
morphogenesis of a branching structure GO:0001763 203 0.145
canonical wnt signaling pathway involved in metanephric kidney development GO:0061290 2 0.143
secondary alcohol metabolic process GO:1902652 3 0.143
associative learning GO:0008306 61 0.143
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.142
embryonic limb morphogenesis GO:0030326 126 0.141
inositol lipid mediated signaling GO:0048017 41 0.141
regulation of protein catabolic process GO:0042176 108 0.141
cell fate commitment GO:0045165 210 0.139
regulation of fat cell differentiation GO:0045598 81 0.139
vitamin metabolic process GO:0006766 23 0.139
oogenesis GO:0048477 56 0.138
positive regulation of peptide secretion GO:0002793 33 0.138
learning or memory GO:0007611 148 0.137
developmental maturation GO:0021700 193 0.135
female mating behavior GO:0060180 8 0.133
endocrine system development GO:0035270 98 0.132
alcohol biosynthetic process GO:0046165 43 0.130
nephron development GO:0072006 109 0.130
regulation of cellular amino acid metabolic process GO:0006521 5 0.129
positive regulation of protein kinase activity GO:0045860 144 0.128
Human
cellular water homeostasis GO:0009992 2 0.128
decidualization GO:0046697 10 0.127
wnt signaling pathway involved in kidney development GO:0061289 2 0.127
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.126
nucleotide metabolic process GO:0009117 332 0.124
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.123
valine metabolic process GO:0006573 4 0.122
Mouse
regulation of activated t cell proliferation GO:0046006 16 0.120
tissue remodeling GO:0048771 102 0.119
acylglycerol biosynthetic process GO:0046463 18 0.119
positive regulation of cellular amine metabolic process GO:0033240 5 0.118
cellular response to lipopolysaccharide GO:0071222 77 0.118
bone development GO:0060348 120 0.117
mast cell proliferation GO:0070662 4 0.117
positive regulation of lipid metabolic process GO:0045834 40 0.117
regulation of protein localization to nucleus GO:1900180 60 0.116
stem cell division GO:0017145 30 0.116
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.115
intracellular protein transport GO:0006886 204 0.115
ion transmembrane transport GO:0034220 361 0.115
cellular response to inorganic substance GO:0071241 37 0.114
limb development GO:0060173 166 0.114
b cell activation GO:0042113 161 0.114
camp biosynthetic process GO:0006171 31 0.113
neuron apoptotic process GO:0051402 142 0.112
myeloid leukocyte differentiation GO:0002573 119 0.112
purine containing compound biosynthetic process GO:0072522 70 0.111
prostate epithelial cord elongation GO:0060523 3 0.110
response to stilbenoid GO:0035634 22 0.110
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.110
odontogenesis GO:0042476 78 0.109
digestive system development GO:0055123 200 0.107
bile acid metabolic process GO:0008206 17 0.107
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.107
regulation of apoptotic signaling pathway GO:2001233 197 0.106
cellular glucan metabolic process GO:0006073 32 0.106
camp metabolic process GO:0046058 40 0.105
regulation of kinase activity GO:0043549 249 0.104
Human
cellular macromolecule catabolic process GO:0044265 206 0.103
purine containing compound metabolic process GO:0072521 311 0.103
insulin receptor signaling pathway GO:0008286 49 0.102
regulation of homeostatic process GO:0032844 182 0.102
tricarboxylic acid metabolic process GO:0072350 5 0.102
Mouse
lateral line system development GO:0048925 1 0.102
response to interferon gamma GO:0034341 34 0.101
regulation of fatty acid beta oxidation GO:0031998 1 0.100
cell proliferation in hindbrain GO:0021534 10 0.100
neuron migration GO:0001764 122 0.100
negative regulation of cell growth GO:0030308 44 0.100
icosanoid metabolic process GO:0006690 33 0.100
protein catabolic process GO:0030163 221 0.098
epithelial cell development GO:0002064 159 0.098
nucleobase containing small molecule metabolic process GO:0055086 352 0.098
drug metabolic process GO:0017144 4 0.098
smooth muscle cell migration GO:0014909 10 0.098
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.098
cellular amide metabolic process GO:0043603 58 0.098
Mouse
anatomical structure homeostasis GO:0060249 145 0.097
nuclear import GO:0051170 95 0.096
nephron epithelium morphogenesis GO:0072088 68 0.095
cellular alcohol metabolic process GO:0044107 3 0.095
monocarboxylic acid catabolic process GO:0072329 27 0.095
embryonic appendage morphogenesis GO:0035113 126 0.095
asymmetric neuroblast division GO:0055059 1 0.094
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.094
signal transduction in absence of ligand GO:0038034 55 0.094
appendage development GO:0048736 166 0.094
cellular response to interferon gamma GO:0071346 25 0.094
positive regulation of nucleotide metabolic process GO:0045981 114 0.094
positive regulation of lymphocyte proliferation GO:0050671 70 0.093
purine nucleotide biosynthetic process GO:0006164 65 0.093
positive regulation of peptide hormone secretion GO:0090277 31 0.093
cellular modified amino acid metabolic process GO:0006575 63 0.093
Mouse
multi organism behavior GO:0051705 62 0.092
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.092
regulation of body fluid levels GO:0050878 162 0.092
regulation of cholesterol transport GO:0032374 17 0.092
regulation of nucleocytoplasmic transport GO:0046822 73 0.091
positive regulation of activated t cell proliferation GO:0042104 8 0.090
norepinephrine epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001994 3 0.090
glycogen metabolic process GO:0005977 32 0.090
blood circulation GO:0008015 195 0.088
positive regulation of cellular response to insulin stimulus GO:1900078 9 0.087
multi multicellular organism process GO:0044706 109 0.087
androgen metabolic process GO:0008209 11 0.087
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.086
regulation of leukocyte apoptotic process GO:2000106 56 0.086
phosphatidylinositol mediated signaling GO:0048015 41 0.086
citrate metabolic process GO:0006101 3 0.086
Mouse
response to ethanol GO:0045471 18 0.086
protein import into nucleus GO:0006606 95 0.086
forebrain development GO:0030900 302 0.085
skeletal system development GO:0001501 356 0.085
phospholipid homeostasis GO:0055091 6 0.085
trophectodermal cellular morphogenesis GO:0001831 3 0.084
positive regulation of camp biosynthetic process GO:0030819 19 0.084
mesonephric tubule development GO:0072164 94 0.084
glycolytic process GO:0006096 20 0.084
cellular metal ion homeostasis GO:0006875 151 0.083
prostate gland epithelium morphogenesis GO:0060740 31 0.083
negative regulation of neuron death GO:1901215 98 0.083
glucocorticoid biosynthetic process GO:0006704 5 0.082
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.082
naphthalene metabolic process GO:0018931 1 0.082
positive regulation of wnt signaling pathway GO:0030177 45 0.082
pancreas development GO:0031016 57 0.081
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.081
regulation of protein processing GO:0070613 96 0.081
cellular amino acid metabolic process GO:0006520 103 0.081
Mouse
negative regulation of secretion by cell GO:1903531 54 0.081
kidney epithelium development GO:0072073 121 0.080
reactive oxygen species metabolic process GO:0072593 84 0.080
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.080
regulation of renal sodium excretion GO:0035813 3 0.079
negative regulation of cell migration GO:0030336 59 0.079
segmentation GO:0035282 93 0.078
adaptive immune response GO:0002250 155 0.078
acetylcholine metabolic process GO:0008291 3 0.078
benzene containing compound metabolic process GO:0042537 5 0.078
fat cell differentiation GO:0045444 160 0.078
nucleotide biosynthetic process GO:0009165 78 0.078
positive regulation of hydrolase activity GO:0051345 148 0.077
regulation of innate immune response GO:0045088 91 0.077
regulation of intracellular protein transport GO:0033157 82 0.077
response to estradiol GO:0032355 12 0.077
activation of cysteine type endopeptidase activity GO:0097202 27 0.077
limb morphogenesis GO:0035108 149 0.076
peptide hormone secretion GO:0030072 109 0.076
interleukin 2 biosynthetic process GO:0042094 15 0.076
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.076
short chain fatty acid catabolic process GO:0019626 2 0.076
positive regulation of proteolysis GO:0045862 85 0.076
appendage morphogenesis GO:0035107 149 0.075
peptidyl amino acid modification GO:0018193 336 0.074
Mouse
polyol metabolic process GO:0019751 26 0.074
regulation of cell motility GO:2000145 236 0.074
cellular homeostasis GO:0019725 240 0.073
inner ear receptor cell differentiation GO:0060113 61 0.073
positive regulation of fatty acid metabolic process GO:0045923 8 0.073
regulation of t cell differentiation GO:0045580 83 0.073
positive regulation of protein phosphorylation GO:0001934 242 0.073
Human Mouse
regulation of cell growth GO:0001558 91 0.073
positive regulation of endopeptidase activity GO:0010950 43 0.073
cytoplasmic transport GO:0016482 234 0.073
regulation of dopamine uptake involved in synaptic transmission GO:0051584 2 0.073
regulation of transferase activity GO:0051338 263 0.072
Human
morphogenesis of a branching epithelium GO:0061138 193 0.072
cellular response to biotic stimulus GO:0071216 92 0.072
regulation of morphogenesis of a branching structure GO:0060688 53 0.072
embryonic organ morphogenesis GO:0048562 276 0.072
renal sodium excretion GO:0035812 3 0.072
response to interleukin 15 GO:0070672 3 0.072
sodium ion homeostasis GO:0055078 7 0.072
response to lipopolysaccharide GO:0032496 128 0.072
respiratory tube development GO:0030323 167 0.072
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.072
organic hydroxy compound transport GO:0015850 93 0.072
regulation of cysteine type endopeptidase activity GO:2000116 65 0.071
regulation of intestinal cholesterol absorption GO:0030300 4 0.071
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.071
purine nucleotide metabolic process GO:0006163 302 0.071
regulation of toll like receptor signaling pathway GO:0034121 20 0.071
positive regulation of epithelial cell proliferation GO:0050679 68 0.070
sertoli cell differentiation GO:0060008 18 0.070
follicle stimulating hormone secretion GO:0046884 1 0.070

Prlr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.102
disease of anatomical entity DOID:7 0 0.080
vascular disease DOID:178 0 0.080
cardiovascular system disease DOID:1287 0 0.080