Mus musculus

217 known processes

Prnp

prion protein

(Aliases: PrPSc,PrPC,Prn-p,AI325101,Prn-i,CD230,PrP<C>,AA960666,Sinc,PrP)

Prnp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
copper ion homeostasis GO:0055070 9 1.000
cellular copper ion homeostasis GO:0006878 8 1.000
rna polyadenylation GO:0043631 6 1.000
regulation of epidermal growth factor activated receptor activity GO:0007176 7 1.000
mrna polyadenylation GO:0006378 5 1.000
rna 3 end processing GO:0031123 20 0.999
mrna 3 end processing GO:0031124 16 0.998
axon cargo transport GO:0008088 33 0.996
visual behavior GO:0007632 45 0.996
sterol metabolic process GO:0016125 58 0.995
ionotropic glutamate receptor signaling pathway GO:0035235 29 0.991
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.991
cellular transition metal ion homeostasis GO:0046916 32 0.990
visual learning GO:0008542 44 0.983
regulation of protein tyrosine kinase activity GO:0061097 17 0.981
positive regulation of neuron projection development GO:0010976 79 0.980
single organism cell adhesion GO:0098602 156 0.969
cell adhesion GO:0007155 329 0.961
cholesterol metabolic process GO:0008203 56 0.953
neuronal action potential GO:0019228 54 0.948
microtubule based movement GO:0007018 84 0.935
cellular metal ion homeostasis GO:0006875 151 0.929
response to light stimulus GO:0009416 135 0.920
regulation of cell cycle g2 m phase transition GO:1902749 10 0.918
amine metabolic process GO:0009308 45 0.916
extracellular matrix organization GO:0030198 147 0.901
feeding behavior GO:0007631 62 0.890
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 5 0.888
cation homeostasis GO:0055080 212 0.887
positive regulation of cell cycle phase transition GO:1901989 17 0.879
chemotaxis GO:0006935 247 0.870
regulation of cellular amine metabolic process GO:0033238 20 0.867
associative learning GO:0008306 61 0.853
regulation of neuron projection development GO:0010975 169 0.850
locomotory behavior GO:0007626 195 0.849
regulation of kinase activity GO:0043549 249 0.848
microtubule based transport GO:0010970 50 0.843
axon ensheathment GO:0008366 76 0.839
regulation of receptor activity GO:0010469 41 0.838
regulation of cellular response to stress GO:0080135 159 0.807
regulation of cellular amino acid metabolic process GO:0006521 5 0.799
negative regulation of protein metabolic process GO:0051248 282 0.792
positive regulation of cell projection organization GO:0031346 95 0.790
regulation of epidermal growth factor receptor signaling pathway GO:0042058 13 0.789
peptidyl tyrosine phosphorylation GO:0018108 143 0.780
glutamate receptor signaling pathway GO:0007215 35 0.779
cytoskeleton dependent intracellular transport GO:0030705 50 0.773
ensheathment of neurons GO:0007272 76 0.773
metal ion homeostasis GO:0055065 189 0.772
learning GO:0007612 98 0.772
plasma membrane organization GO:0007009 90 0.763
extracellular structure organization GO:0043062 148 0.756
regulation of neuron death GO:1901214 134 0.751
homotypic cell cell adhesion GO:0034109 28 0.750
regulation of erbb signaling pathway GO:1901184 16 0.746
cellular chemical homeostasis GO:0055082 215 0.739
cell recognition GO:0008037 83 0.736
cellular amine metabolic process GO:0044106 44 0.726
adult locomotory behavior GO:0008344 91 0.723
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.700
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.688
peptidyl proline hydroxylation GO:0019511 3 0.671
inclusion body assembly GO:0070841 3 0.650
regulation of beta amyloid clearance GO:1900221 1 0.645
response to radiation GO:0009314 165 0.642
molting cycle GO:0042303 90 0.638
divalent inorganic cation homeostasis GO:0072507 138 0.625
single organismal cell cell adhesion GO:0016337 131 0.624
steroid metabolic process GO:0008202 119 0.613
positive regulation of beta amyloid formation GO:1902004 4 0.613
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.610
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.607
smooth endoplasmic reticulum calcium ion homeostasis GO:0051563 2 0.591
negative regulation of cellular amide metabolic process GO:0034249 4 0.587
cellular amino acid metabolic process GO:0006520 103 0.580
cytokine production GO:0001816 319 0.578
endomembrane system organization GO:0010256 147 0.573
cognition GO:0050890 149 0.572
alcohol metabolic process GO:0006066 116 0.572
regulation of cellular ketone metabolic process GO:0010565 66 0.568
midbrain development GO:0030901 35 0.565
regulation of cell projection organization GO:0031344 206 0.557
neuron death GO:0070997 154 0.551
positive regulation of necrotic cell death GO:0010940 1 0.551
response to oxidative stress GO:0006979 123 0.549
positive regulation of proteolysis GO:0045862 85 0.548
apoptotic signaling pathway GO:0097190 306 0.544
cellular ion homeostasis GO:0006873 165 0.536
negative regulation of neuron death GO:1901215 98 0.532
multicellular organismal signaling GO:0035637 91 0.525
action potential GO:0001508 78 0.524
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.522
glial cell differentiation GO:0010001 131 0.521
regulation of inclusion body assembly GO:0090083 1 0.514
erbb signaling pathway GO:0038127 32 0.511
negative regulation of molecular function GO:0044092 258 0.494
neuron recognition GO:0008038 25 0.488
organic hydroxy compound metabolic process GO:1901615 203 0.484
cellular homeostasis GO:0019725 240 0.477
transition metal ion homeostasis GO:0055076 54 0.476
cellular response to growth factor stimulus GO:0071363 197 0.473
regulation of mitotic cell cycle phase transition GO:1901990 73 0.451
regulation of cell cycle process GO:0010564 160 0.439
peptidyl amino acid modification GO:0018193 336 0.439
cellular calcium ion homeostasis GO:0006874 119 0.437
regulation of peptidase activity GO:0052547 96 0.435
regulation of protein processing GO:0070613 96 0.430
neuron projection guidance GO:0097485 141 0.427
cellular response to oxidative stress GO:0034599 76 0.413
vesicle docking involved in exocytosis GO:0006904 7 0.412
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.410
regulation of protein maturation GO:1903317 96 0.408
synaptic growth at neuromuscular junction GO:0051124 6 0.405
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.404
positive regulation of innate immune response GO:0045089 80 0.400
activation of mapk activity involved in innate immune response GO:0035419 2 0.398
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.397
regulation of cellular catabolic process GO:0031329 242 0.396
terminal button organization GO:0072553 3 0.394
peptidyl tyrosine modification GO:0018212 145 0.380
regulation of response to oxidative stress GO:1902882 19 0.376
regulation of neuron differentiation GO:0045664 281 0.376
regulation of translation GO:0006417 71 0.376
epidermal growth factor receptor signaling pathway GO:0007173 28 0.372
regulation of g2 m transition of mitotic cell cycle GO:0010389 10 0.371
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.357
cell cycle g2 m phase transition GO:0044839 20 0.356
sodium ion export from cell GO:0036376 1 0.355
regulation of thymocyte migration GO:2000410 2 0.352
beta amyloid clearance GO:0097242 2 0.350
cell junction maintenance GO:0034331 4 0.345
positive regulation of programmed cell death GO:0043068 218 0.343
regulation of transferase activity GO:0051338 263 0.338
purine nucleotide metabolic process GO:0006163 302 0.335
cholesterol catabolic process GO:0006707 5 0.331
negative regulation of neuron differentiation GO:0045665 101 0.329
cellular protein catabolic process GO:0044257 155 0.320
ribonucleoside monophosphate catabolic process GO:0009158 57 0.316
peripheral nervous system development GO:0007422 53 0.316
regulation of protein stability GO:0031647 52 0.315
positive regulation of kinase activity GO:0033674 155 0.312
regulation of endocytosis GO:0030100 69 0.307
regulation of cell cycle GO:0051726 281 0.305
myelination GO:0042552 74 0.302
developmental cell growth GO:0048588 84 0.300
cellular divalent inorganic cation homeostasis GO:0072503 127 0.299
response to growth factor GO:0070848 198 0.298
ribose phosphate metabolic process GO:0019693 291 0.295
protein catabolic process GO:0030163 221 0.287
sodium ion export GO:0071436 2 0.286
locomotory exploration behavior GO:0035641 10 0.286
regulation of neurofibrillary tangle assembly GO:1902996 1 0.285
positive regulation of protein catabolic process GO:0045732 60 0.284
heterocycle catabolic process GO:0046700 280 0.283
regulation of cell cycle phase transition GO:1901987 77 0.276
translation GO:0006412 93 0.276
negative regulation of nervous system development GO:0051961 156 0.274
regulation of cell migration GO:0030334 219 0.273
transmission of nerve impulse GO:0019226 76 0.265
long term memory GO:0007616 15 0.263
learning or memory GO:0007611 148 0.262
nucleoside monophosphate metabolic process GO:0009123 85 0.261
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.258
positive regulation of eosinophil migration GO:2000418 2 0.255
response to reactive oxygen species GO:0000302 56 0.252
mrna processing GO:0006397 63 0.246
positive regulation of mitotic cell cycle GO:0045931 41 0.244
negative regulation of endopeptidase activity GO:0010951 44 0.244
regulation of proteolysis GO:0030162 164 0.239
calcium mediated signaling GO:0019722 46 0.239
calcium ion homeostasis GO:0055074 127 0.239
ribonucleoside monophosphate metabolic process GO:0009161 80 0.236
purine containing compound metabolic process GO:0072521 311 0.236
activation of immune response GO:0002253 138 0.232
beta amyloid metabolic process GO:0050435 14 0.232
negative regulation of beta amyloid formation GO:1902430 4 0.231
reactive nitrogen species metabolic process GO:2001057 0 0.227
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.226
positive regulation of apoptotic signaling pathway GO:2001235 95 0.223
microglial cell activation GO:0001774 3 0.222
intrinsic apoptotic signaling pathway GO:0097193 132 0.222
oligodendrocyte differentiation GO:0048709 53 0.220
mating behavior GO:0007617 20 0.219
glycosyl compound catabolic process GO:1901658 206 0.218
hindbrain development GO:0030902 128 0.217
regulation of cellular response to oxidative stress GO:1900407 19 0.216
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.216
leukocyte migration GO:0050900 124 0.215
positive regulation of defense response GO:0031349 124 0.214
calcium ion transmembrane transport GO:0070588 85 0.213
positive regulation of amyloid precursor protein catabolic process GO:1902993 4 0.210
cation transport GO:0006812 399 0.209
negative regulation of peptidase activity GO:0010466 46 0.206
response to iron ion GO:0010039 4 0.205
peptide metabolic process GO:0006518 46 0.204
membrane organization GO:0061024 245 0.204
response to misfolded protein GO:0051788 5 0.203
cellular response to dna damage stimulus GO:0006974 207 0.200
adherens junction maintenance GO:0034334 1 0.198
carbohydrate derivative catabolic process GO:1901136 231 0.198
negative regulation of cellular protein metabolic process GO:0032269 247 0.197
mrna metabolic process GO:0016071 84 0.196
posttranscriptional regulation of gene expression GO:0010608 155 0.195
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.194
positive regulation of cytokine production GO:0001819 174 0.193
developmental maturation GO:0021700 193 0.192
regulation of mitotic cell cycle GO:0007346 126 0.190
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000060 8 0.189
regulation of defense response GO:0031347 233 0.189
cellular protein complex assembly GO:0043623 116 0.188
protein folding GO:0006457 28 0.185
cellular ketone metabolic process GO:0042180 84 0.185
regulation of eosinophil migration GO:2000416 2 0.184
positive regulation of cell adhesion GO:0045785 80 0.183
negative regulation of protein processing GO:0010955 79 0.183
cell maturation GO:0048469 127 0.182
myelination in peripheral nervous system GO:0022011 19 0.182
clathrin mediated endocytosis GO:0072583 7 0.179
protein lipid complex subunit organization GO:0071825 12 0.177
cellular amide metabolic process GO:0043603 58 0.175
neuron maturation GO:0042551 29 0.174
positive regulation of transferase activity GO:0051347 167 0.172
negative regulation of cell development GO:0010721 169 0.170
membrane protein proteolysis GO:0033619 10 0.170
purine nucleoside triphosphate catabolic process GO:0009146 203 0.169
protein maturation GO:0051604 176 0.169
mapk cascade GO:0000165 281 0.168
negative regulation of hydrolase activity GO:0051346 71 0.168
nucleobase containing small molecule metabolic process GO:0055086 352 0.166
ribonucleoside triphosphate catabolic process GO:0009203 199 0.166
multicellular organism growth GO:0035264 161 0.166
immune response activating signal transduction GO:0002757 116 0.166
mitotic cell cycle process GO:1903047 159 0.165
purine ribonucleotide metabolic process GO:0009150 290 0.165
activation of innate immune response GO:0002218 56 0.165
cerebellum development GO:0021549 77 0.164
memory GO:0007613 58 0.164
sterol catabolic process GO:0016127 5 0.161
negative regulation of amyloid precursor protein catabolic process GO:1902992 5 0.160
gliogenesis GO:0042063 141 0.158
response to topologically incorrect protein GO:0035966 25 0.158
spermatogenesis GO:0007283 284 0.157
protein modification by small protein conjugation GO:0032446 187 0.155
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.152
regulation of innate immune response GO:0045088 91 0.150
positive regulation of calcium mediated signaling GO:0050850 15 0.149
exploration behavior GO:0035640 21 0.149
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.148
second messenger mediated signaling GO:0019932 73 0.147
regulation of protein catabolic process GO:0042176 108 0.146
nucleoside triphosphate catabolic process GO:0009143 205 0.145
purine nucleotide catabolic process GO:0006195 211 0.142
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.142
response to organic cyclic compound GO:0014070 198 0.139
positive regulation of thymocyte migration GO:2000412 2 0.138
macromolecule catabolic process GO:0009057 281 0.138
body morphogenesis GO:0010171 45 0.137
regulation of response to reactive oxygen species GO:1901031 9 0.136
eosinophil migration GO:0072677 3 0.135
regulation of protein complex assembly GO:0043254 83 0.134
neuron apoptotic process GO:0051402 142 0.134
regulation of t cell activation GO:0050863 170 0.134
endocytosis GO:0006897 168 0.133
positive regulation of potassium ion transport GO:0043268 3 0.132
regulation of chemotaxis GO:0050920 53 0.131
transmembrane transport GO:0055085 412 0.131
vesicle docking GO:0048278 7 0.130
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.130
regulation of vesicle mediated transport GO:0060627 139 0.130
innate immune response activating signal transduction GO:0002758 50 0.128
regulation of purine nucleotide metabolic process GO:1900542 169 0.126
organic cyclic compound catabolic process GO:1901361 295 0.126
negative regulation of cellular component organization GO:0051129 194 0.126
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.125
plasma lipoprotein particle remodeling GO:0034369 6 0.125
muscle system process GO:0003012 141 0.125
nucleotide metabolic process GO:0009117 332 0.125
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.123
myeloid leukocyte migration GO:0097529 57 0.122
protein processing GO:0016485 163 0.122
leukocyte chemotaxis GO:0030595 69 0.121
plasma lipoprotein particle organization GO:0071827 11 0.121
cell growth GO:0016049 130 0.120
positive regulation of protein modification process GO:0031401 299 0.120
developmental growth involved in morphogenesis GO:0060560 138 0.119
response to ammonium ion GO:0060359 21 0.119
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.117
cell cell adhesion GO:0098609 41 0.117
spermatid differentiation GO:0048515 115 0.116
glycosyl compound metabolic process GO:1901657 246 0.116
mitotic cell cycle GO:0000278 195 0.116
nucleoside triphosphate metabolic process GO:0009141 230 0.115
reactive oxygen species biosynthetic process GO:1903409 8 0.115
thymocyte migration GO:0072679 2 0.115
regulation of transporter activity GO:0032409 57 0.114
rna processing GO:0006396 105 0.114
regulation of apoptotic signaling pathway GO:2001233 197 0.114
extracellular matrix dependent thymocyte migration GO:0072680 1 0.114
positive regulation of cell cycle g2 m phase transition GO:1902751 5 0.114
organophosphate ester transport GO:0015748 28 0.113
positive regulation of secretion by cell GO:1903532 114 0.113
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.112
fibronectin dependent thymocyte migration GO:0072681 1 0.110
reactive oxygen species metabolic process GO:0072593 84 0.108
central nervous system neuron differentiation GO:0021953 162 0.108
regulation of nucleoside metabolic process GO:0009118 130 0.107
positive regulation of growth GO:0045927 104 0.105
ubiquitin dependent protein catabolic process GO:0006511 129 0.105
leukocyte migration involved in inflammatory response GO:0002523 7 0.105
regulation of reactive oxygen species metabolic process GO:2000377 40 0.105
protein kinase b signaling GO:0043491 74 0.102
regulation of hydrolase activity GO:0051336 246 0.102
synapse organization GO:0050808 125 0.102
protein stabilization GO:0050821 25 0.100
negative regulation of proteolysis GO:0045861 74 0.100
adult behavior GO:0030534 135 0.100
positive regulation of map kinase activity GO:0043406 84 0.100
cellular nitrogen compound catabolic process GO:0044270 280 0.100
steroid esterification GO:0034433 3 0.099
positive regulation of potassium ion transmembrane transport GO:1901381 3 0.099
positive regulation of nervous system development GO:0051962 221 0.099
regulation of membrane potential GO:0042391 192 0.098
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.098
regulation of amyloid precursor protein catabolic process GO:1902991 8 0.097
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.097
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.097
neuromuscular process controlling balance GO:0050885 59 0.097
nucleoside monophosphate catabolic process GO:0009125 59 0.096
sperm individualization GO:0007291 1 0.095
phagosome maturation GO:0090382 4 0.095
negative regulation of multi organism process GO:0043901 68 0.094
protein hydroxylation GO:0018126 4 0.094
nucleoside metabolic process GO:0009116 246 0.094
cholesterol homeostasis GO:0042632 44 0.092
conditioned taste aversion GO:0001661 4 0.092
regulation of tau protein kinase activity GO:1902947 1 0.091
regulation of mapk cascade GO:0043408 248 0.091
response to glycoside GO:1903416 2 0.091
positive regulation of cell cycle process GO:0090068 61 0.091
response to oxygen levels GO:0070482 62 0.090
positive regulation of sodium ion transport GO:0010765 13 0.089
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.089
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.088
positive regulation of cardiac muscle tissue development GO:0055025 19 0.088
receptor mediated endocytosis GO:0006898 51 0.087
cell chemotaxis GO:0060326 81 0.087
positive regulation of cell death GO:0010942 224 0.086
response to steroid hormone GO:0048545 56 0.086
cellularization GO:0007349 1 0.085
regulation of amyloid precursor protein biosynthetic process GO:0042984 3 0.085
activation of mapk activity GO:0000187 59 0.085
organophosphate catabolic process GO:0046434 232 0.084
protein modification by small protein conjugation or removal GO:0070647 207 0.084
inflammatory response GO:0006954 244 0.084
neurofibrillary tangle assembly GO:1902988 1 0.084
protein localization to juxtaparanode region of axon GO:0071205 4 0.083
very low density lipoprotein particle remodeling GO:0034372 1 0.083
regulation of endopeptidase activity GO:0052548 89 0.082
receptor internalization GO:0031623 16 0.080
leukocyte cell cell adhesion GO:0007159 14 0.080
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.080
regulation of protein kinase activity GO:0045859 232 0.080
regulation of protein serine threonine kinase activity GO:0071900 157 0.079
modification dependent macromolecule catabolic process GO:0043632 133 0.079
regulation of cellular protein catabolic process GO:1903362 61 0.079
negative regulation of response to wounding GO:1903035 77 0.078
sterol esterification GO:0034434 3 0.078
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.077
potassium ion import GO:0010107 1 0.076
g2 m transition of mitotic cell cycle GO:0000086 20 0.075
negative regulation of erbb signaling pathway GO:1901185 7 0.075
response to transforming growth factor beta GO:0071559 88 0.074
glial cell development GO:0021782 54 0.074
positive regulation of cell cycle GO:0045787 92 0.074
spermatid development GO:0007286 108 0.073
mating GO:0007618 27 0.073
negative regulation of cell projection organization GO:0031345 56 0.071
nucleotide catabolic process GO:0009166 217 0.071
positive regulation of cell motility GO:2000147 116 0.071
copper ion transport GO:0006825 10 0.071
metencephalon development GO:0022037 89 0.069
cellular response to ethanol GO:0071361 3 0.068
neuron remodeling GO:0016322 7 0.068
protein localization to membrane GO:0072657 108 0.068
phagocytosis engulfment GO:0006911 16 0.068
cellular response to topologically incorrect protein GO:0035967 25 0.068
negative regulation of cytokine production GO:0001818 84 0.066
guanosine containing compound metabolic process GO:1901068 144 0.065
blood vessel morphogenesis GO:0048514 285 0.065
regulation of t cell proliferation GO:0042129 92 0.065
cellular modified amino acid metabolic process GO:0006575 63 0.064
heart morphogenesis GO:0003007 178 0.064
regulation of protein binding GO:0043393 60 0.063
positive regulation of phagocytosis GO:0050766 26 0.063
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.063
protein localization to plasma membrane GO:0072659 57 0.063
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.063
negative regulation of protein maturation GO:1903318 79 0.062
regulation of cell motility GO:2000145 236 0.062
axonogenesis GO:0007409 274 0.061
positive regulation of tumor necrosis factor production GO:0032760 30 0.061
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.061
ribonucleoside catabolic process GO:0042454 206 0.061
ribonucleotide catabolic process GO:0009261 208 0.061
engulfment of apoptotic cell GO:0043652 3 0.061
negative regulation of mapk cascade GO:0043409 65 0.060
synapse assembly GO:0007416 56 0.060
purine nucleoside monophosphate catabolic process GO:0009128 58 0.060
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.060
macrophage activation GO:0042116 27 0.059
regulation of protein kinase b signaling GO:0051896 56 0.059
positive regulation of cellular protein catabolic process GO:1903364 34 0.059
membrane invagination GO:0010324 17 0.058
atp metabolic process GO:0046034 75 0.058
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.058
tumor necrosis factor production GO:0032640 50 0.058
cell cell recognition GO:0009988 44 0.058
cholesterol transport GO:0030301 38 0.058
response to transition metal nanoparticle GO:1990267 11 0.057
synaptic transmission GO:0007268 329 0.057
cholesterol esterification GO:0034435 3 0.057
axon guidance GO:0007411 141 0.056
pole plasm assembly GO:0007315 2 0.056
cellular macromolecule catabolic process GO:0044265 206 0.056
cardiac muscle contraction GO:0060048 32 0.055
lipoprotein metabolic process GO:0042157 43 0.055
synaptic vesicle membrane organization GO:0048499 1 0.055
meiotic cell cycle process GO:1903046 77 0.054
meiotic nuclear division GO:0007126 115 0.054
potassium ion transport GO:0006813 52 0.053
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.053
cellular response to oxygen radical GO:0071450 14 0.053
response to superoxide GO:0000303 16 0.052
lipoprotein biosynthetic process GO:0042158 33 0.051
carboxylic acid biosynthetic process GO:0046394 86 0.051
positive regulation of lymphocyte activation GO:0051251 140 0.051
transition metal ion transport GO:0000041 38 0.050
neuron neuron synaptic transmission GO:0007270 69 0.050
regulation of cytokine production GO:0001817 266 0.050
substantia nigra development GO:0021762 2 0.050
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.050
anion transport GO:0006820 177 0.050
t cell activation GO:0042110 289 0.049
nucleoside catabolic process GO:0009164 206 0.049
purine nucleoside triphosphate metabolic process GO:0009144 226 0.049
regulation of cellular component size GO:0032535 121 0.049
myeloid leukocyte activation GO:0002274 83 0.049
cellular sodium ion homeostasis GO:0006883 1 0.049
mesenchyme development GO:0060485 152 0.048
regulation of binding GO:0051098 111 0.048
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.048
peripheral nervous system axon regeneration GO:0014012 2 0.046
regulation of fibronectin dependent thymocyte migration GO:2000413 1 0.046
reverse cholesterol transport GO:0043691 6 0.046
cellular response to hormone stimulus GO:0032870 150 0.046
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.046
positive regulation of mapk cascade GO:0043410 170 0.046
removal of superoxide radicals GO:0019430 12 0.045
single fertilization GO:0007338 82 0.045
leukocyte proliferation GO:0070661 172 0.045
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.045
copper ion transmembrane transport GO:0035434 5 0.045
negative regulation of response to dna damage stimulus GO:2001021 10 0.044
positive regulation of ion transport GO:0043270 65 0.044
coagulation GO:0050817 78 0.044
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.043
cellular response to molecule of bacterial origin GO:0071219 83 0.043
peptidyl proline modification GO:0018208 6 0.042

Prnp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.972
Human
nervous system disease DOID:863 0 0.972
Human
central nervous system disease DOID:331 0 0.968
Human
brain disease DOID:936 0 0.968
Human
disease of metabolism DOID:0014667 0 0.946
amyloidosis DOID:9120 0 0.946
acquired metabolic disease DOID:0060158 0 0.946
sensory system disease DOID:0050155 0 0.745
eye and adnexa disease DOID:1492 0 0.745
cerebral degeneration DOID:1443 0 0.694
dementia DOID:1307 0 0.629
alzheimer s disease DOID:10652 0 0.629
disease of mental health DOID:150 0 0.629
tauopathy DOID:680 0 0.629
neurodegenerative disease DOID:1289 0 0.629
cognitive disorder DOID:1561 0 0.629
inherited metabolic disorder DOID:655 0 0.261
immune system disease DOID:2914 0 0.193
cancer DOID:162 0 0.191
disease of cellular proliferation DOID:14566 0 0.191
organ system cancer DOID:0050686 0 0.191
eye disease DOID:5614 0 0.142
retinal disease DOID:5679 0 0.140
retinal degeneration DOID:8466 0 0.140
lipid storage disease DOID:9455 0 0.118
lysosomal storage disease DOID:3211 0 0.118
sphingolipidosis DOID:1927 0 0.118
lymphatic system disease DOID:75 0 0.086
degeneration of macula and posterior pole DOID:2007 0 0.056
macular degeneration DOID:4448 0 0.056
age related macular degeneration DOID:10871 0 0.056