Mus musculus

339 known processes

Prox1

prospero-related homeobox 1

(Aliases: A230003G05Rik)

Prox1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.966
cellular ketone metabolic process GO:0042180 84 0.963
Human
cellular amino acid metabolic process GO:0006520 103 0.922
regulation of cellular amine metabolic process GO:0033238 20 0.910
glial cell differentiation GO:0010001 131 0.907
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.899
regulation of cellular ketone metabolic process GO:0010565 66 0.853
Human
central nervous system neuron development GO:0021954 67 0.850
Zebrafish
glial cell development GO:0021782 54 0.807
cellular amine metabolic process GO:0044106 44 0.804
telencephalon development GO:0021537 186 0.784
circadian rhythm GO:0007623 114 0.782
axon guidance GO:0007411 141 0.773
Fly
central nervous system neuron differentiation GO:0021953 162 0.770
neuron projection guidance GO:0097485 141 0.764
Fly
positive regulation of nervous system development GO:0051962 221 0.750
stem cell differentiation GO:0048863 268 0.749
chemotaxis GO:0006935 247 0.740
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.738
regulation of hormone levels GO:0010817 211 0.736
gliogenesis GO:0042063 141 0.730
Fly
amide transport GO:0042886 138 0.729
camera type eye development GO:0043010 266 0.716
forebrain neuron development GO:0021884 30 0.708
Zebrafish
organic hydroxy compound metabolic process GO:1901615 203 0.685
Human
muscle tissue development GO:0060537 308 0.680
skin development GO:0043588 220 0.668
Zebrafish
myeloid cell differentiation GO:0030099 233 0.666
peptide transport GO:0015833 133 0.625
regulation of peptide hormone secretion GO:0090276 75 0.618
rhythmic process GO:0048511 174 0.617
peptide secretion GO:0002790 114 0.605
transmembrane transport GO:0055085 412 0.603
gland development GO:0048732 330 0.603
forebrain development GO:0030900 302 0.598
neuron migration GO:0001764 122 0.590
axonogenesis GO:0007409 274 0.589
Fly
cardiac muscle tissue development GO:0048738 130 0.577
cation transport GO:0006812 399 0.575
peptide hormone secretion GO:0030072 109 0.573
immune effector process GO:0002252 321 0.570
aortic valve morphogenesis GO:0003180 4 0.568
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.568
epidermis development GO:0008544 187 0.556
Zebrafish
developmental maturation GO:0021700 193 0.550
forebrain generation of neurons GO:0021872 63 0.543
heart morphogenesis GO:0003007 178 0.523
angiogenesis GO:0001525 201 0.520
regulation of blood circulation GO:1903522 93 0.515
sensory organ morphogenesis GO:0090596 242 0.511
epithelial tube morphogenesis GO:0060562 303 0.501
ear development GO:0043583 200 0.495
cerebral cortex development GO:0021987 86 0.494
regionalization GO:0003002 337 0.492
cell fate commitment GO:0045165 210 0.486
hindbrain development GO:0030902 128 0.478
regulation of peptide transport GO:0090087 91 0.476
negative regulation of protein metabolic process GO:0051248 282 0.474
epithelial cell development GO:0002064 159 0.474
axonal fasciculation GO:0007413 15 0.471
regulation of heart contraction GO:0008016 77 0.466
mechanoreceptor differentiation GO:0042490 67 0.463
Zebrafish
regulation of homeostatic process GO:0032844 182 0.456
regulation of organ morphogenesis GO:2000027 144 0.451
Fly
intracellular receptor signaling pathway GO:0030522 74 0.440
regulation of hormone secretion GO:0046883 88 0.440
regulation of kinase activity GO:0043549 249 0.438
Human
cell fate determination GO:0001709 32 0.423
regulation of circadian rhythm GO:0042752 58 0.414
Human
regulation of peptide secretion GO:0002791 77 0.413
stem cell development GO:0048864 219 0.412
nerve development GO:0021675 67 0.407
Fly
insulin secretion GO:0030073 89 0.402
positive regulation of neuron differentiation GO:0045666 141 0.402
regulation of secretion by cell GO:1903530 249 0.401
embryonic placenta development GO:0001892 98 0.399
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.398
cranial nerve development GO:0021545 41 0.393
negative regulation of cellular protein metabolic process GO:0032269 247 0.393
embryonic organ morphogenesis GO:0048562 276 0.392
locomotory behavior GO:0007626 195 0.378
tube formation GO:0035148 140 0.376
regulation of embryonic development GO:0045995 71 0.370
peptidyl amino acid modification GO:0018193 336 0.366
neural tube development GO:0021915 160 0.364
kidney development GO:0001822 213 0.362
Human
positive regulation of protein modification process GO:0031401 299 0.362
Human
urogenital system development GO:0001655 261 0.359
Human
myeloid leukocyte differentiation GO:0002573 119 0.358
mesenchymal cell development GO:0014031 93 0.356
telencephalon cell migration GO:0022029 55 0.350
leukocyte differentiation GO:0002521 342 0.350
regulation of system process GO:0044057 200 0.350
organ growth GO:0035265 117 0.342
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.342
Fly
mesenchyme development GO:0060485 152 0.341
ear morphogenesis GO:0042471 118 0.341
catecholamine metabolic process GO:0006584 30 0.333
cardiac ventricle development GO:0003231 83 0.331
nucleoside phosphate metabolic process GO:0006753 338 0.328
negative regulation of molecular function GO:0044092 258 0.327
Human Zebrafish
regulation of cell motility GO:2000145 236 0.326
Human Zebrafish
detection of stimulus GO:0051606 84 0.325
ensheathment of neurons GO:0007272 76 0.321
cell adhesion GO:0007155 329 0.320
muscle tissue morphogenesis GO:0060415 53 0.318
pallium development GO:0021543 120 0.317
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.315
oligodendrocyte development GO:0014003 20 0.313
regulation of secretion GO:0051046 274 0.307
hormone secretion GO:0046879 128 0.304
regulation of transmembrane transport GO:0034762 128 0.296
mitral valve development GO:0003174 4 0.295
limbic system development GO:0021761 72 0.293
nitrogen compound transport GO:0071705 271 0.292
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.291
Human Zebrafish
ion transmembrane transport GO:0034220 361 0.289
regulation of mast cell differentiation GO:0060375 3 0.285
epithelial cell proliferation GO:0050673 174 0.284
cardiocyte differentiation GO:0035051 87 0.282
detection of external stimulus GO:0009581 61 0.281
ephrin receptor signaling pathway GO:0048013 20 0.281
positive regulation of growth GO:0045927 104 0.278
cerebellum development GO:0021549 77 0.273
multi multicellular organism process GO:0044706 109 0.271
Fly
regulation of ion transport GO:0043269 215 0.267
mitral valve morphogenesis GO:0003183 4 0.266
phenol containing compound metabolic process GO:0018958 60 0.266
ameboidal type cell migration GO:0001667 128 0.263
Human
cellular response to lipid GO:0071396 145 0.262
tissue migration GO:0090130 68 0.260
Human
astrocyte differentiation GO:0048708 43 0.259
retina morphogenesis in camera type eye GO:0060042 45 0.258
digestive tract development GO:0048565 190 0.257
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.257
trophoblast giant cell differentiation GO:0060707 15 0.256
cranial nerve morphogenesis GO:0021602 26 0.255
hippocampus development GO:0021766 52 0.255
regulation of cytokine production GO:0001817 266 0.254
photoreceptor cell differentiation GO:0046530 52 0.253
Fly
neuronal action potential GO:0019228 54 0.251
primary neural tube formation GO:0014020 95 0.249
inflammatory response GO:0006954 244 0.248
positive regulation of homeostatic process GO:0032846 64 0.248
pancreatic pp cell differentiation GO:0003312 2 0.248
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.244
cognition GO:0050890 149 0.243
cell differentiation involved in embryonic placenta development GO:0060706 26 0.243
striated muscle cell proliferation GO:0014855 39 0.241
adult walking behavior GO:0007628 41 0.239
learning or memory GO:0007611 148 0.238
neural tube closure GO:0001843 90 0.238
muscle cell differentiation GO:0042692 261 0.237
regulation of gtp catabolic process GO:0033124 113 0.233
mesenchymal cell differentiation GO:0048762 107 0.230
central nervous system projection neuron axonogenesis GO:0021952 21 0.229
morphogenesis of embryonic epithelium GO:0016331 159 0.228
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.228
cation transmembrane transport GO:0098655 266 0.227
ossification GO:0001503 216 0.226
cellular lipid metabolic process GO:0044255 323 0.226
positive regulation of mapk cascade GO:0043410 170 0.223
g protein coupled receptor signaling pathway GO:0007186 243 0.222
regulation of leukocyte differentiation GO:1902105 159 0.222
renal tubule development GO:0061326 87 0.221
response to organonitrogen compound GO:0010243 246 0.218
negative regulation of cell proliferation GO:0008285 296 0.218
ribonucleotide metabolic process GO:0009259 291 0.216
placenta development GO:0001890 140 0.216
metencephalon development GO:0022037 89 0.214
cellular homeostasis GO:0019725 240 0.212
spinal cord development GO:0021510 81 0.212
cardiac right ventricle formation GO:0003219 3 0.212
negative regulation of neuron projection development GO:0010977 50 0.208
Fly
fatty acid metabolic process GO:0006631 121 0.207
peripheral nervous system development GO:0007422 53 0.207
Zebrafish Fly
regulation of circadian sleep wake cycle GO:0042749 3 0.204
response to monosaccharide GO:0034284 67 0.204
mitochondrion distribution GO:0048311 4 0.201
regulation of epithelial cell proliferation GO:0050678 141 0.201
Human
action potential GO:0001508 78 0.201
neuron recognition GO:0008038 25 0.200
small molecule biosynthetic process GO:0044283 132 0.199
Human
regulation of ras gtpase activity GO:0032318 88 0.199
transmission of nerve impulse GO:0019226 76 0.198
associative learning GO:0008306 61 0.197
diencephalon development GO:0021536 63 0.196
cardiac muscle cell proliferation GO:0060038 31 0.194
auditory receptor cell fate determination GO:0042668 3 0.194
heart contraction GO:0060047 93 0.194
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.194
ribonucleoside triphosphate catabolic process GO:0009203 199 0.194
cardiac muscle tissue morphogenesis GO:0055008 44 0.192
multi organism reproductive behavior GO:0044705 29 0.192
Fly
cellular metal ion homeostasis GO:0006875 151 0.191
cardiac muscle cell differentiation GO:0055007 69 0.191
regulation of reproductive process GO:2000241 66 0.191
heart process GO:0003015 94 0.190
nuclear transport GO:0051169 139 0.187
tissue remodeling GO:0048771 102 0.187
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.185
embryonic epithelial tube formation GO:0001838 130 0.185
smoothened signaling pathway GO:0007224 105 0.180
positive regulation of cholesterol homeostasis GO:2000189 2 0.180
organic cyclic compound catabolic process GO:1901361 295 0.179
glucose homeostasis GO:0042593 128 0.178
blood circulation GO:0008015 195 0.177
muscle cell proliferation GO:0033002 52 0.177
epithelial cell migration GO:0010631 63 0.176
Human
feeding behavior GO:0007631 62 0.174
tube closure GO:0060606 91 0.174
cardiac chamber morphogenesis GO:0003206 93 0.174
learning GO:0007612 98 0.174
regulation of cell projection organization GO:0031344 206 0.171
Fly
neuron death GO:0070997 154 0.169
protein localization to organelle GO:0033365 185 0.169
Fly
detection of temperature stimulus involved in sensory perception GO:0050961 6 0.169
transdifferentiation GO:0060290 1 0.169
negative regulation of synapse maturation GO:2000297 2 0.168
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.167
purine containing compound metabolic process GO:0072521 311 0.167
monocarboxylic acid metabolic process GO:0032787 191 0.166
Human
purine containing compound catabolic process GO:0072523 213 0.166
cerebral cortex cell migration GO:0021795 44 0.166
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.165
tendon cell differentiation GO:0035990 4 0.163
positive regulation of transferase activity GO:0051347 167 0.162
Human
ribose phosphate metabolic process GO:0019693 291 0.162
sensory perception of temperature stimulus GO:0050951 9 0.162
nucleoside metabolic process GO:0009116 246 0.162
ventricular cardiac muscle tissue development GO:0003229 38 0.161
fasciculation of sensory neuron axon GO:0097155 3 0.160
organonitrogen compound catabolic process GO:1901565 264 0.160
oligodendrocyte differentiation GO:0048709 53 0.160
regulation of membrane potential GO:0042391 192 0.160
connective tissue development GO:0061448 179 0.159
negative regulation of neuron death GO:1901215 98 0.159
digestive system development GO:0055123 200 0.158
kidney epithelium development GO:0072073 121 0.157
heart growth GO:0060419 45 0.157
cardiac cell fate determination GO:0060913 2 0.156
cation homeostasis GO:0055080 212 0.155
cholesterol homeostasis GO:0042632 44 0.155
divalent inorganic cation homeostasis GO:0072507 138 0.154
optic nerve development GO:0021554 8 0.153
sensory system development GO:0048880 3 0.153
Zebrafish
organophosphate catabolic process GO:0046434 232 0.153
adult behavior GO:0030534 135 0.151
nucleotide catabolic process GO:0009166 217 0.151
nucleoside catabolic process GO:0009164 206 0.151
lipid biosynthetic process GO:0008610 179 0.151
Human
muscle system process GO:0003012 141 0.151
cellular carbohydrate metabolic process GO:0044262 119 0.150
synaptic transmission GO:0007268 329 0.150
neural crest cell differentiation GO:0014033 54 0.149
positive regulation of cellular catabolic process GO:0031331 148 0.147
regulation of nucleotide catabolic process GO:0030811 122 0.147
blood vessel morphogenesis GO:0048514 285 0.147
regulation of purine nucleotide catabolic process GO:0033121 122 0.146
b cell differentiation GO:0030183 78 0.146
forebrain neuron differentiation GO:0021879 52 0.145
cardiac epithelial to mesenchymal transition GO:0060317 18 0.144
regulation of cholesterol homeostasis GO:2000188 9 0.142
regulation of inflammatory response GO:0050727 147 0.142
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.141
negative regulation of protein modification process GO:0031400 163 0.141
guanosine containing compound metabolic process GO:1901068 144 0.141
divalent inorganic cation transport GO:0072511 178 0.141
inorganic ion transmembrane transport GO:0098660 234 0.140
neural crest cell migration GO:0001755 32 0.140
regulation of mapk cascade GO:0043408 248 0.140
regulation of hydrolase activity GO:0051336 246 0.140
forebrain cell migration GO:0021885 58 0.140
regulation of organelle organization GO:0033043 289 0.139
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.139
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.139
negative regulation of cellular amine metabolic process GO:0033239 1 0.138
nucleocytoplasmic transport GO:0006913 139 0.138
inorganic cation transmembrane transport GO:0098662 207 0.137
cytokine production GO:0001816 319 0.136
regulation of cardiac muscle contraction GO:0055117 21 0.135
gastrulation GO:0007369 116 0.134
myelination GO:0042552 74 0.134
carbohydrate metabolic process GO:0005975 230 0.132
regulation of muscle tissue development GO:1901861 97 0.130
skeletal system development GO:0001501 356 0.130
cellular response to carbohydrate stimulus GO:0071322 50 0.127
regulation of dendritic spine morphogenesis GO:0061001 17 0.127
regulation of erythrocyte differentiation GO:0045646 23 0.127
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.126
regulation of striated muscle contraction GO:0006942 25 0.126
calcium ion homeostasis GO:0055074 127 0.125
cell recognition GO:0008037 83 0.124
regulation of anatomical structure size GO:0090066 178 0.124
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.124
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.121
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.121
regulation of voltage gated calcium channel activity GO:1901385 4 0.121
axon ensheathment GO:0008366 76 0.121
ribonucleoside metabolic process GO:0009119 245 0.120
semaphorin plexin signaling pathway GO:0071526 21 0.119
ribonucleotide catabolic process GO:0009261 208 0.119
multicellular organismal signaling GO:0035637 91 0.118
lymphocyte differentiation GO:0030098 242 0.117
neuron projection extension GO:1990138 64 0.116
establishment or maintenance of cell polarity GO:0007163 86 0.116
odontogenesis GO:0042476 78 0.115
cellular chemical homeostasis GO:0055082 215 0.115
female gonad development GO:0008585 71 0.115
hemangioblast cell differentiation GO:0060217 1 0.115
carbohydrate homeostasis GO:0033500 128 0.115
nucleobase containing small molecule metabolic process GO:0055086 352 0.114
cellular nitrogen compound catabolic process GO:0044270 280 0.114
purine ribonucleotide catabolic process GO:0009154 208 0.113
cytoplasmic transport GO:0016482 234 0.113
fertilization GO:0009566 127 0.112
cell maturation GO:0048469 127 0.112
maintenance of location GO:0051235 89 0.112
gtp catabolic process GO:0006184 143 0.112
purine nucleotide metabolic process GO:0006163 302 0.112
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.111
leukocyte activation involved in immune response GO:0002366 126 0.111
endothelial cell migration GO:0043542 44 0.110
Human
glycosyl compound metabolic process GO:1901657 246 0.109
response to radiation GO:0009314 165 0.108
muscle contraction GO:0006936 101 0.108
regulation of body fluid levels GO:0050878 162 0.107
purine nucleotide catabolic process GO:0006195 211 0.106
purine nucleoside triphosphate metabolic process GO:0009144 226 0.106
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.106
cardiac muscle tissue growth GO:0055017 37 0.106
cerebellar purkinje cell layer development GO:0021680 26 0.105
fasciculation of motor neuron axon GO:0097156 2 0.105
glycosyl compound catabolic process GO:1901658 206 0.105
lipid homeostasis GO:0055088 63 0.105
cell division GO:0051301 120 0.105
Fly
divalent metal ion transport GO:0070838 172 0.104
peptidyl tyrosine phosphorylation GO:0018108 143 0.104
positive regulation of cell cycle GO:0045787 92 0.104
lateral line system development GO:0048925 1 0.104
Zebrafish
response to light stimulus GO:0009416 135 0.103
retinal ganglion cell axon guidance GO:0031290 18 0.103
striated muscle contraction GO:0006941 45 0.103
nucleoside triphosphate catabolic process GO:0009143 205 0.102
negative regulation of ovulation GO:0060280 1 0.102
rho protein signal transduction GO:0007266 32 0.102
negative regulation of phosphorus metabolic process GO:0010563 184 0.101
appendage development GO:0048736 166 0.099
regulation of neuron differentiation GO:0045664 281 0.099
central nervous system myelination GO:0022010 12 0.098
regulation of neuron death GO:1901214 134 0.098
germ cell development GO:0007281 185 0.098
response to temperature stimulus GO:0009266 55 0.098
detection of abiotic stimulus GO:0009582 60 0.098
purine ribonucleotide metabolic process GO:0009150 290 0.097
sensory perception GO:0007600 245 0.097
Fly
regulation of cell cycle GO:0051726 281 0.097
ribonucleoside catabolic process GO:0042454 206 0.097
negative regulation of protein phosphorylation GO:0001933 126 0.097
single organism nuclear import GO:1902593 95 0.096
endocardial cushion to mesenchymal transition GO:0090500 5 0.096
negative regulation of ion transport GO:0043271 28 0.096
organic acid biosynthetic process GO:0016053 86 0.096
Human
regulation of nucleoside metabolic process GO:0009118 130 0.095
rac protein signal transduction GO:0016601 13 0.095
cellular calcium ion homeostasis GO:0006874 119 0.095
purine nucleoside catabolic process GO:0006152 205 0.094
digestive tract morphogenesis GO:0048546 147 0.094
gonad development GO:0008406 141 0.094
aromatic compound catabolic process GO:0019439 286 0.094
regulation of myeloid leukocyte differentiation GO:0002761 58 0.094
regulation of protein transport GO:0051223 163 0.094
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.093
ribonucleoside triphosphate metabolic process GO:0009199 220 0.093
pancreatic a cell fate commitment GO:0003326 2 0.093
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.092
t cell activation GO:0042110 289 0.092
intracellular distribution of mitochondria GO:0048312 1 0.092
positive regulation of cell development GO:0010720 237 0.091
regulation of neuron apoptotic process GO:0043523 122 0.091
positive regulation of map kinase activity GO:0043406 84 0.091
positive regulation of synaptic plasticity GO:0031915 4 0.091
regulation of epithelial cell migration GO:0010632 35 0.091
Human
negative regulation of cellular component organization GO:0051129 194 0.090
Fly
synapse organization GO:0050808 125 0.090
Fly
organonitrogen compound biosynthetic process GO:1901566 192 0.090
cellular response to monosaccharide stimulus GO:0071326 47 0.090
keratinocyte proliferation GO:0043616 21 0.089
negative regulation of phosphorylation GO:0042326 166 0.089
nucleotide metabolic process GO:0009117 332 0.089
regulation of carbohydrate metabolic process GO:0006109 75 0.089
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.089
ras protein signal transduction GO:0007265 77 0.088
regulation of cell migration GO:0030334 219 0.088
Human Zebrafish
auditory receptor cell fate specification GO:0042667 1 0.088
lung cell differentiation GO:0060479 30 0.088
nucleoside triphosphate metabolic process GO:0009141 230 0.087
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.087
b cell activation GO:0042113 161 0.087
embryonic heart tube development GO:0035050 65 0.087
dendritic spine development GO:0060996 30 0.087
negative regulation of neuron differentiation GO:0045665 101 0.087
Fly
positive regulation of neuron projection development GO:0010976 79 0.087
response to lipopolysaccharide GO:0032496 128 0.087
mesoderm morphogenesis GO:0048332 64 0.086
calcium ion transport GO:0006816 159 0.086
negative regulation of cell cycle GO:0045786 123 0.086
epithelium migration GO:0090132 63 0.086
Human
lens development in camera type eye GO:0002088 62 0.085
regulation of purine nucleotide metabolic process GO:1900542 169 0.084
neural tube formation GO:0001841 108 0.084
inner ear receptor cell differentiation GO:0060113 61 0.084
positive regulation of translational initiation GO:0045948 4 0.084
establishment of protein localization to organelle GO:0072594 118 0.084
cardiac muscle contraction GO:0060048 32 0.084
positive regulation of cell motility GO:2000147 116 0.084
Human
cell type specific apoptotic process GO:0097285 268 0.083
mapk cascade GO:0000165 281 0.083
extracellular matrix organization GO:0030198 147 0.083
carbohydrate derivative catabolic process GO:1901136 231 0.083
cellular component assembly involved in morphogenesis GO:0010927 139 0.083
regulation of neuron projection development GO:0010975 169 0.083
Fly
glandular epithelial cell differentiation GO:0002067 38 0.082
bone remodeling GO:0046849 53 0.082
regulation of actin filament based process GO:0032970 99 0.082
negative regulation of nervous system development GO:0051961 156 0.082
Fly
purine nucleoside metabolic process GO:0042278 241 0.082
regulation of cellular catabolic process GO:0031329 242 0.082
detection of stimulus involved in sensory perception GO:0050906 44 0.081
neuron neuron synaptic transmission GO:0007270 69 0.081
visceral serous pericardium development GO:0061032 2 0.081
heterocycle catabolic process GO:0046700 280 0.081
regulation of nucleotide metabolic process GO:0006140 169 0.081
protein import into nucleus GO:0006606 95 0.081
retina development in camera type eye GO:0060041 119 0.081
negative regulation of phosphate metabolic process GO:0045936 184 0.081
pancreatic pp cell fate commitment GO:0003329 2 0.081
regulation of ion transmembrane transport GO:0034765 119 0.081
nephron tubule development GO:0072080 84 0.080
formation of primary germ layer GO:0001704 77 0.080
wound healing GO:0042060 157 0.080
positive regulation of kinase activity GO:0033674 155 0.080
Human
stem cell maintenance GO:0019827 130 0.080
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.079
Fly
regulation of protein kinase activity GO:0045859 232 0.079
Human
erythrocyte differentiation GO:0030218 88 0.079
lipid storage GO:0019915 36 0.079
regulation of stem cell differentiation GO:2000736 50 0.078
acetylcholine transport GO:0015870 2 0.078
regulation of jak stat cascade GO:0046425 34 0.078
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.077
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.077
morphogenesis of a branching epithelium GO:0061138 193 0.077
regulation of vesicle mediated transport GO:0060627 139 0.077
organelle localization GO:0051640 179 0.077
mammary gland epithelium development GO:0061180 65 0.076
regulation of leukocyte proliferation GO:0070663 121 0.076
canonical wnt signaling pathway GO:0060070 130 0.076
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.076
megakaryocyte differentiation GO:0030219 26 0.076
operant conditioning GO:0035106 2 0.075
regulation of transferase activity GO:0051338 263 0.075
Human
female sex differentiation GO:0046660 84 0.075
sodium ion transport GO:0006814 73 0.075
regulation of intracellular transport GO:0032386 159 0.074
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.074
directional locomotion GO:0033058 3 0.074
second messenger mediated signaling GO:0019932 73 0.074
regulation of keratinocyte proliferation GO:0010837 15 0.073
clara cell differentiation GO:0060486 4 0.073
jak stat cascade GO:0007259 42 0.073
autonomic nervous system development GO:0048483 43 0.072
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.072
regulation of synaptic plasticity GO:0048167 87 0.072
dendritic spine morphogenesis GO:0060997 22 0.072
response to organic cyclic compound GO:0014070 198 0.072
metal ion homeostasis GO:0055065 189 0.071
inner ear morphogenesis GO:0042472 101 0.071
stress activated protein kinase signaling cascade GO:0031098 81 0.071
calcium mediated signaling GO:0019722 46 0.071
motor neuron migration GO:0097475 4 0.071
nuclear import GO:0051170 95 0.070
purine ribonucleoside metabolic process GO:0046128 241 0.070
erythrocyte maturation GO:0043249 6 0.070
neuromuscular process GO:0050905 99 0.070
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.070
regulation of protein serine threonine kinase activity GO:0071900 157 0.070
Human
nucleoside phosphate catabolic process GO:1901292 222 0.070
negative regulation of transferase activity GO:0051348 85 0.070
hair cell differentiation GO:0035315 40 0.070
Zebrafish
protein localization to nucleus GO:0034504 121 0.070
Fly
motor neuron axon guidance GO:0008045 26 0.069
chromatin organization GO:0006325 206 0.069
acetylcholine secretion neurotransmission GO:0014055 2 0.069
negative regulation of cell development GO:0010721 169 0.068
Fly
epithelial tube formation GO:0072175 130 0.068

Prox1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.099
disease of anatomical entity DOID:7 0 0.076
nervous system disease DOID:863 0 0.076