Mus musculus

0 known processes

Prpf8

pre-mRNA processing factor 8

(Aliases: DBF3/PRP8,Sfprp8l,AU019467,Prp8,D11Bwg0410e)

Prpf8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
covalent chromatin modification GO:0016569 163 0.558
chromatin organization GO:0006325 206 0.248
protein modification by small protein conjugation or removal GO:0070647 207 0.223
histone modification GO:0016570 159 0.170
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.163
cellular response to dna damage stimulus GO:0006974 207 0.157
dna metabolic process GO:0006259 303 0.141
positive regulation of dna templated transcription elongation GO:0032786 2 0.137
protein methylation GO:0006479 81 0.126
protein ubiquitination GO:0016567 171 0.120
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.115
Human Fly
chromatin modification GO:0016568 187 0.111
dna alkylation GO:0006305 43 0.096
purine nucleoside catabolic process GO:0006152 205 0.089
mrna metabolic process GO:0016071 84 0.089
Human Fly
protein modification by small protein removal GO:0070646 21 0.082
regulation of cell cycle GO:0051726 281 0.080
histone methylation GO:0016571 71 0.079
methylation GO:0032259 134 0.078
peptidyl lysine modification GO:0018205 77 0.077
intracellular protein transport GO:0006886 204 0.075
macromolecule methylation GO:0043414 120 0.074
nuclear export GO:0051168 34 0.072
chromatin disassembly GO:0031498 1 0.071
epithalamus development GO:0021538 2 0.069
peptidyl amino acid modification GO:0018193 336 0.068
histone deubiquitination GO:0016578 2 0.067
autophagy GO:0006914 45 0.066
tube closure GO:0060606 91 0.065
heterocycle catabolic process GO:0046700 280 0.065
organonitrogen compound catabolic process GO:1901565 264 0.064
regulation of chromatin modification GO:1903308 57 0.063
intracellular receptor signaling pathway GO:0030522 74 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.061
rna splicing GO:0008380 54 0.060
Human Fly
immune effector process GO:0002252 321 0.060
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.059
stem cell maintenance GO:0019827 130 0.058
innate immune response GO:0045087 157 0.057
carbohydrate derivative catabolic process GO:1901136 231 0.056
cellular ketone metabolic process GO:0042180 84 0.056
regulation of organelle organization GO:0033043 289 0.053
positive regulation of protein modification process GO:0031401 299 0.051
regulation of histone modification GO:0031056 56 0.051
regulation of chromatin silencing GO:0031935 2 0.050
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.050
protein processing GO:0016485 163 0.050
ribonucleotide catabolic process GO:0009261 208 0.050
stem cell development GO:0048864 219 0.050
response to nutrient levels GO:0031667 109 0.049
regulation of myeloid leukocyte differentiation GO:0002761 58 0.049
rna processing GO:0006396 105 0.049
Human Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.048
macromolecular complex disassembly GO:0032984 43 0.047
misfolded protein transport GO:0070843 1 0.046
regulation of response to alcohol GO:1901419 2 0.046
nucleocytoplasmic transport GO:0006913 139 0.045
purine nucleoside triphosphate metabolic process GO:0009144 226 0.045
response to radiation GO:0009314 165 0.045
dna repair GO:0006281 107 0.044
histone h4 acetylation GO:0043967 10 0.044
defense response to bacterium GO:0042742 119 0.043
glycosyl compound metabolic process GO:1901657 246 0.043
gland development GO:0048732 330 0.040
cellular amino acid metabolic process GO:0006520 103 0.040
dna methylation GO:0006306 43 0.039
regulation of cell cycle checkpoint GO:1901976 9 0.039
action potential GO:0001508 78 0.039
regulation of protein serine threonine kinase activity GO:0071900 157 0.038
astral microtubule organization GO:0030953 3 0.038
protein modification by small protein conjugation GO:0032446 187 0.038
response to extracellular stimulus GO:0009991 127 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
positive regulation of histone methylation GO:0031062 16 0.037
nuclear transport GO:0051169 139 0.036
stem cell differentiation GO:0048863 268 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
dendrite development GO:0016358 115 0.036
modification dependent protein catabolic process GO:0019941 133 0.035
nucleic acid transport GO:0050657 18 0.035
wnt signaling pathway GO:0016055 188 0.035
regulation of chromosome organization GO:0033044 83 0.034
cytoplasmic transport GO:0016482 234 0.034
amine metabolic process GO:0009308 45 0.034
cellular amine metabolic process GO:0044106 44 0.034
blastocyst development GO:0001824 80 0.033
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.033
primary neural tube formation GO:0014020 95 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
maintenance of location GO:0051235 89 0.032
copii coated vesicle budding GO:0090114 2 0.031
gonad development GO:0008406 141 0.031
Worm
purine containing compound metabolic process GO:0072521 311 0.031
aromatic compound catabolic process GO:0019439 286 0.031
transcription from rna polymerase iii promoter GO:0006383 3 0.031
transmission of nerve impulse GO:0019226 76 0.031
microtubule cytoskeleton organization GO:0000226 157 0.031
regulation of chromatin organization GO:1902275 57 0.031
mrna transport GO:0051028 13 0.030
negative regulation of synapse assembly GO:0051964 3 0.030
defense response to other organism GO:0098542 197 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
purine containing compound catabolic process GO:0072523 213 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.029
vitamin d receptor signaling pathway GO:0070561 2 0.029
regulation of antimicrobial humoral response GO:0002759 3 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
regulation of wnt signaling pathway GO:0030111 123 0.028
nuclear division GO:0000280 158 0.028
axon ensheathment GO:0008366 76 0.027
regulation of mrna metabolic process GO:1903311 43 0.027
ossification GO:0001503 216 0.027
protein targeting GO:0006605 143 0.027
regulation of myeloid cell differentiation GO:0045637 96 0.027
positive regulation of neuron projection development GO:0010976 79 0.027
protein oligomerization GO:0051259 67 0.027
cognition GO:0050890 149 0.026
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.026
dna modification GO:0006304 50 0.026
morphogenesis of embryonic epithelium GO:0016331 159 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
myeloid leukocyte differentiation GO:0002573 119 0.026
neural tube development GO:0021915 160 0.025
ribonucleoside monophosphate catabolic process GO:0009158 57 0.025
gliogenesis GO:0042063 141 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
regulation of mitotic cell cycle phase transition GO:1901990 73 0.025
nucleotide catabolic process GO:0009166 217 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
blastocyst growth GO:0001832 23 0.024
regulation of cell cycle process GO:0010564 160 0.024
ensheathment of neurons GO:0007272 76 0.024
regulation of rna splicing GO:0043484 37 0.024
histone h4 k16 acetylation GO:0043984 3 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
regulation of protein localization GO:0032880 231 0.023
fat cell differentiation GO:0045444 160 0.023
protein maturation GO:0051604 176 0.023
localization within membrane GO:0051668 4 0.023
glial cell differentiation GO:0010001 131 0.023
regulation of neuron projection development GO:0010975 169 0.023
protein deubiquitination GO:0016579 19 0.022
negative regulation of molecular function GO:0044092 258 0.022
nucleotide metabolic process GO:0009117 332 0.022
regulation of map kinase activity GO:0043405 120 0.022
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.022
skeletal system development GO:0001501 356 0.022
response to organic cyclic compound GO:0014070 198 0.022
cytoplasmic translational initiation GO:0002183 3 0.021
cellular response to external stimulus GO:0071496 88 0.021
protein alkylation GO:0008213 81 0.021
mrna export from nucleus GO:0006406 11 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
positive regulation of chromosome organization GO:2001252 33 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
myeloid cell differentiation GO:0030099 233 0.021
synaptonemal complex assembly GO:0007130 13 0.021
chemotaxis GO:0006935 247 0.021
transcription coupled nucleotide excision repair GO:0006283 2 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.020
regulation of protein stability GO:0031647 52 0.020
meiotic nuclear division GO:0007126 115 0.020
regulation of protein complex assembly GO:0043254 83 0.020
negative regulation of protein maturation GO:1903318 79 0.020
positive regulation of defense response to bacterium GO:1900426 1 0.020
rna localization GO:0006403 23 0.020
regulation of cell division GO:0051302 76 0.020
neural tube closure GO:0001843 90 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
regulation of histone methylation GO:0031060 30 0.019
multi multicellular organism process GO:0044706 109 0.019
regulation of neuron differentiation GO:0045664 281 0.019
rhythmic process GO:0048511 174 0.019
receptor biosynthetic process GO:0032800 3 0.019
regulation of cell substrate adhesion GO:0010810 73 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
regulation of cell projection organization GO:0031344 206 0.019
dna templated transcription elongation GO:0006354 13 0.019
ribonucleoprotein complex subunit organization GO:0071826 28 0.018
Human
defense response to virus GO:0051607 68 0.018
lymphocyte differentiation GO:0030098 242 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
negative regulation of proteolysis GO:0045861 74 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
nucleoside metabolic process GO:0009116 246 0.018
epithelial tube formation GO:0072175 130 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
response to endoplasmic reticulum stress GO:0034976 53 0.018
negative regulation of cell size GO:0045792 3 0.018
glial cell development GO:0021782 54 0.018
cellular response to starvation GO:0009267 57 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.018
response to growth factor GO:0070848 198 0.018
atp metabolic process GO:0046034 75 0.018
positive regulation of histone modification GO:0031058 28 0.018
carbohydrate biosynthetic process GO:0016051 74 0.017
embryonic skeletal system development GO:0048706 120 0.017
microtubule nucleation GO:0007020 2 0.017
lipid localization GO:0010876 126 0.017
establishment of rna localization GO:0051236 18 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of multi organism process GO:0043900 111 0.017
response to inorganic substance GO:0010035 96 0.017
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.017
memory GO:0007613 58 0.017
leukocyte differentiation GO:0002521 342 0.017
myelination GO:0042552 74 0.017
nucleoside monophosphate catabolic process GO:0009125 59 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
ribonucleoprotein complex disassembly GO:0032988 3 0.016
endomembrane system organization GO:0010256 147 0.016
somite development GO:0061053 81 0.016
cellular hyperosmotic salinity response GO:0071475 0 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
regulation of dna templated transcription elongation GO:0032784 10 0.016
regulation of transcription by chromatin organization GO:0034401 0 0.016
positive regulation of defense response GO:0031349 124 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
meiotic cell cycle GO:0051321 122 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
tube formation GO:0035148 140 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of glucose metabolic process GO:0010906 60 0.016
renal system development GO:0072001 225 0.016
antimicrobial peptide production GO:0002775 2 0.016
multicellular organismal signaling GO:0035637 91 0.015
mrna splicing via spliceosome GO:0000398 43 0.015
Human Fly
cell junction organization GO:0034330 77 0.015
cell fate determination involved in pattern specification GO:0060582 1 0.015
dna templated transcription initiation GO:0006352 13 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
hindbrain development GO:0030902 128 0.015
axis elongation GO:0003401 30 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
protein import into nucleus GO:0006606 95 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
response to light stimulus GO:0009416 135 0.015
spermatid differentiation GO:0048515 115 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
neural tube formation GO:0001841 108 0.015
response to acid chemical GO:0001101 111 0.015
positive regulation of immune effector process GO:0002699 107 0.015
regulation of cell activation GO:0050865 289 0.015
cellular protein complex disassembly GO:0043624 36 0.015
membrane organization GO:0061024 245 0.015
intracellular mrna localization GO:0008298 4 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.014
trna wobble uridine modification GO:0002098 2 0.014
cellular protein complex assembly GO:0043623 116 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
male gamete generation GO:0048232 285 0.014
rna splicing via transesterification reactions GO:0000375 43 0.014
Human Fly
lipid storage GO:0019915 36 0.014
positive regulation of chromatin modification GO:1903310 28 0.014
regulation of antimicrobial peptide production GO:0002784 1 0.014
ameboidal type cell migration GO:0001667 128 0.014
regulation of carbohydrate metabolic process GO:0006109 75 0.014
cell cycle arrest GO:0007050 37 0.014
mesenchyme development GO:0060485 152 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
negative regulation of neuron death GO:1901215 98 0.014
regulation of t cell activation GO:0050863 170 0.014
mitotic cell cycle GO:0000278 195 0.014
rna transport GO:0050658 18 0.014
synapsis GO:0007129 34 0.013
ncrna 3 end processing GO:0043628 2 0.013
protein complex disassembly GO:0043241 40 0.013
positive regulation of growth GO:0045927 104 0.013
cell fate commitment GO:0045165 210 0.013
digestive system development GO:0055123 200 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
neuron death GO:0070997 154 0.013
cytokine production GO:0001816 319 0.013
regulation of mrna processing GO:0050684 41 0.013
positive regulation of histone h3 k4 methylation GO:0051571 5 0.013
cellular response to nutrient levels GO:0031669 64 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
regulation of homeostatic process GO:0032844 182 0.013
regulation of response to biotic stimulus GO:0002831 38 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
response to starvation GO:0042594 65 0.013
somitogenesis GO:0001756 69 0.013
dephosphorylation GO:0016311 129 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
adult locomotory behavior GO:0008344 91 0.013
oligodendrocyte differentiation GO:0048709 53 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
liver development GO:0001889 66 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.013
response to reactive oxygen species GO:0000302 56 0.013
response to temperature stimulus GO:0009266 55 0.012
skeletal system morphogenesis GO:0048705 203 0.012
regulation of neuron death GO:1901214 134 0.012
changes to dna methylation involved in embryo development GO:1901538 6 0.012
cellular response to lipid GO:0071396 145 0.012
anatomical structure homeostasis GO:0060249 145 0.012
placenta development GO:0001890 140 0.012
organelle assembly GO:0070925 177 0.012
nucleoside catabolic process GO:0009164 206 0.012
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.012
cell recognition GO:0008037 83 0.012
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.012
positive regulation of wnt signaling pathway GO:0030177 45 0.012
response to sterol GO:0036314 4 0.012
axonogenesis GO:0007409 274 0.012
regulation of protein import into nucleus GO:0042306 52 0.012
protein catabolic process GO:0030163 221 0.012
segmentation GO:0035282 93 0.012
regulation of protein kinase activity GO:0045859 232 0.012
single fertilization GO:0007338 82 0.012
neuronal action potential GO:0019228 54 0.012
axis elongation involved in somitogenesis GO:0090245 4 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
epithelial cell development GO:0002064 159 0.012
regulation of hydrolase activity GO:0051336 246 0.012
viral life cycle GO:0019058 36 0.012
viral process GO:0016032 41 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
habenula development GO:0021986 2 0.011
regulation of proteolysis GO:0030162 164 0.011
interspecies interaction between organisms GO:0044419 83 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
cell adhesion GO:0007155 329 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
regulation of rna export from nucleus GO:0046831 4 0.011
spermatogenesis GO:0007283 284 0.011
positive regulation of nervous system development GO:0051962 221 0.011
positive regulation of organelle organization GO:0010638 128 0.011
regulation of mrna splicing via spliceosome GO:0048024 32 0.011
activation of mapkkk activity GO:0000185 1 0.011
spliceosomal complex disassembly GO:0000390 1 0.011
positive regulation of cell death GO:0010942 224 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
positive regulation of cell development GO:0010720 237 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
internal protein amino acid acetylation GO:0006475 42 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
histone lysine methylation GO:0034968 50 0.011
protein acylation GO:0043543 64 0.011
blood circulation GO:0008015 195 0.011
regulation of neural precursor cell proliferation GO:2000177 70 0.011
ectoderm formation GO:0001705 3 0.011
regulation of dna damage checkpoint GO:2000001 3 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
regulation of cell motility GO:2000145 236 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
skin development GO:0043588 220 0.011
gtp metabolic process GO:0046039 144 0.011
neural precursor cell proliferation GO:0061351 121 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.010
positive regulation of intracellular protein transport GO:0090316 42 0.010
urogenital system development GO:0001655 261 0.010
forebrain development GO:0030900 302 0.010
single organism nuclear import GO:1902593 95 0.010
response to uv GO:0009411 44 0.010
blastocyst hatching GO:0001835 4 0.010
connective tissue development GO:0061448 179 0.010
embryonic skeletal system morphogenesis GO:0048704 91 0.010
sensory perception GO:0007600 245 0.010
mitotic cell cycle process GO:1903047 159 0.010
positive regulation of cell cycle process GO:0090068 61 0.010
muscle cell differentiation GO:0042692 261 0.010
dna dealkylation GO:0035510 11 0.010
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.010
positive regulation of cell projection organization GO:0031346 95 0.010

Prpf8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.025
Human
disease of anatomical entity DOID:7 0 0.025
Human
central nervous system disease DOID:331 0 0.023
neuropathy DOID:870 0 0.017
neuromuscular disease DOID:440 0 0.017
physical disorder DOID:0080015 0 0.011
congenital nervous system abnormality DOID:2490 0 0.011