Mus musculus

0 known processes

Psma4

proteasome (prosome, macropain) subunit, alpha type 4

(Aliases: C9)

Psma4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasome assembly GO:0043248 1 0.972
Yeast
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.910
Yeast
cellular protein catabolic process GO:0044257 155 0.880
Yeast
cellular response to dna damage stimulus GO:0006974 207 0.874
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.695
Yeast
purine ribonucleotide metabolic process GO:0009150 290 0.633
positive regulation of proteolysis GO:0045862 85 0.563
modification dependent macromolecule catabolic process GO:0043632 133 0.514
Yeast
modification dependent protein catabolic process GO:0019941 133 0.458
Yeast
macromolecule catabolic process GO:0009057 281 0.434
Yeast
protein catabolic process GO:0030163 221 0.427
Yeast
mitochondrial fusion GO:0008053 9 0.386
cellular macromolecule catabolic process GO:0044265 206 0.374
Yeast
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.356
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.258
Yeast
ubiquitin dependent protein catabolic process GO:0006511 129 0.257
Yeast
proteasomal protein catabolic process GO:0010498 98 0.231
Yeast
positive regulation of cellular protein catabolic process GO:1903364 34 0.228
ribose phosphate metabolic process GO:0019693 291 0.206
negative regulation of cellular component organization GO:0051129 194 0.206
purine nucleotide catabolic process GO:0006195 211 0.200
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.194
cellular nitrogen compound catabolic process GO:0044270 280 0.179
amine metabolic process GO:0009308 45 0.166
cellular amine metabolic process GO:0044106 44 0.156
molting cycle GO:0042303 90 0.149
ribonucleotide catabolic process GO:0009261 208 0.142
positive regulation of hydrolase activity GO:0051345 148 0.134
purine ribonucleoside metabolic process GO:0046128 241 0.133
spermatogenesis GO:0007283 284 0.132
organic cyclic compound catabolic process GO:1901361 295 0.121
positive regulation of cellular catabolic process GO:0031331 148 0.112
dna repair GO:0006281 107 0.111
nucleic acid transport GO:0050657 18 0.111
regulation of proteolysis GO:0030162 164 0.110
membrane organization GO:0061024 245 0.108
regulation of cellular amine metabolic process GO:0033238 20 0.105
nucleotide metabolic process GO:0009117 332 0.104
purine nucleotide metabolic process GO:0006163 302 0.102
regulation of cellular component biogenesis GO:0044087 181 0.100
positive regulation of protein phosphorylation GO:0001934 242 0.098
nucleoside triphosphate metabolic process GO:0009141 230 0.098
nucleobase containing small molecule metabolic process GO:0055086 352 0.097
positive regulation of peptidase activity GO:0010952 49 0.096
aromatic compound catabolic process GO:0019439 286 0.096
heterocycle catabolic process GO:0046700 280 0.091
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.090
purine containing compound metabolic process GO:0072521 311 0.089
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.088
nucleotide catabolic process GO:0009166 217 0.085
nucleoside catabolic process GO:0009164 206 0.084
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.082
endocytosis GO:0006897 168 0.081
Worm
ribonucleotide metabolic process GO:0009259 291 0.080
regulation of hydrolase activity GO:0051336 246 0.079
ribonucleoside metabolic process GO:0009119 245 0.079
mitochondrial transport GO:0006839 36 0.078
cellular ketone metabolic process GO:0042180 84 0.076
regulation of cellular amino acid metabolic process GO:0006521 5 0.074
dna metabolic process GO:0006259 303 0.073
nucleoside metabolic process GO:0009116 246 0.072
glycosyl compound metabolic process GO:1901657 246 0.072
positive regulation of protein complex assembly GO:0031334 45 0.070
positive regulation of protein catabolic process GO:0045732 60 0.068
negative regulation of organelle organization GO:0010639 90 0.068
mitochondrion organization GO:0007005 134 0.067
apoptotic signaling pathway GO:0097190 306 0.067
cellular protein complex assembly GO:0043623 116 0.067
Yeast
dna recombination GO:0006310 92 0.067
cytoplasmic transport GO:0016482 234 0.065
oocyte anterior posterior axis specification GO:0007314 2 0.065
rna catabolic process GO:0006401 29 0.064
positive regulation of programmed cell death GO:0043068 218 0.063
organonitrogen compound catabolic process GO:1901565 264 0.063
protein import GO:0017038 101 0.062
cation homeostasis GO:0055080 212 0.062
nucleobase containing compound transport GO:0015931 27 0.061
nucleoside phosphate catabolic process GO:1901292 222 0.061
nitrogen compound transport GO:0071705 271 0.060
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.058
regulation of cellular catabolic process GO:0031329 242 0.058
establishment of rna localization GO:0051236 18 0.057
purine nucleoside metabolic process GO:0042278 241 0.056
purine nucleoside catabolic process GO:0006152 205 0.056
positive regulation of organelle organization GO:0010638 128 0.053
positive regulation of protein modification process GO:0031401 299 0.053
regulation of mitochondrion organization GO:0010821 27 0.052
neural tube formation GO:0001841 108 0.052
carbohydrate derivative catabolic process GO:1901136 231 0.052
regulation of organelle organization GO:0033043 289 0.052
gonad development GO:0008406 141 0.051
Worm
regulation of apoptotic signaling pathway GO:2001233 197 0.051
guanosine containing compound metabolic process GO:1901068 144 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.051
positive regulation of apoptotic process GO:0043065 217 0.050
negative regulation of mitochondrion organization GO:0010823 9 0.050
purine nucleoside triphosphate metabolic process GO:0009144 226 0.049
apoptotic mitochondrial changes GO:0008637 48 0.049
protein maturation GO:0051604 176 0.048
positive regulation of endopeptidase activity GO:0010950 43 0.047
extracellular structure organization GO:0043062 148 0.046
ribonucleoside monophosphate metabolic process GO:0009161 80 0.045
leukocyte mediated immunity GO:0002443 174 0.045
negative regulation of alcohol biosynthetic process GO:1902931 4 0.044
regulation of nucleoside metabolic process GO:0009118 130 0.044
male gamete generation GO:0048232 285 0.044
protein import into nucleus GO:0006606 95 0.043
localization within membrane GO:0051668 4 0.043
mapk cascade GO:0000165 281 0.043
negative regulation of cellular amine metabolic process GO:0033239 1 0.043
cellular divalent inorganic cation homeostasis GO:0072503 127 0.042
regulation of phospholipid biosynthetic process GO:0071071 3 0.042
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
translesion synthesis GO:0019985 1 0.040
morphogenesis of embryonic epithelium GO:0016331 159 0.039
leukocyte proliferation GO:0070661 172 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.039
synaptic transmission GO:0007268 329 0.039
purine ribonucleoside catabolic process GO:0046130 205 0.038
positive regulation of cellular component biogenesis GO:0044089 94 0.038
regulation of anatomical structure size GO:0090066 178 0.038
copii coated vesicle budding GO:0090114 2 0.038
cellular homeostasis GO:0019725 240 0.037
regulation of defense response GO:0031347 233 0.037
regulation of purine nucleotide catabolic process GO:0033121 122 0.037
cellular amino acid metabolic process GO:0006520 103 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.036
spermatid differentiation GO:0048515 115 0.036
purine ribonucleoside biosynthetic process GO:0046129 19 0.035
purine ribonucleotide biosynthetic process GO:0009152 59 0.035
protein processing GO:0016485 163 0.035
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.035
regulation of intracellular transport GO:0032386 159 0.035
maternal determination of anterior posterior axis embryo GO:0008358 2 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
negative regulation of apoptotic signaling pathway GO:2001234 104 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.034
regulation of lymphocyte activation GO:0051249 240 0.034
meiotic cell cycle GO:0051321 122 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
t cell activation GO:0042110 289 0.032
nucleoside monophosphate metabolic process GO:0009123 85 0.032
release of cytochrome c from mitochondria GO:0001836 23 0.031
gtp metabolic process GO:0046039 144 0.031
positive regulation of dna templated transcription initiation GO:2000144 5 0.031
purine containing compound catabolic process GO:0072523 213 0.030
regulation of protein targeting GO:1903533 61 0.030
regulation of protein catabolic process GO:0042176 108 0.030
nucleoside phosphate biosynthetic process GO:1901293 79 0.030
nucleoside biosynthetic process GO:0009163 21 0.029
oocyte construction GO:0007308 2 0.029
regulation of cytoskeleton organization GO:0051493 122 0.029
positive regulation of cell death GO:0010942 224 0.029
regulation of protein localization GO:0032880 231 0.028
organophosphate catabolic process GO:0046434 232 0.028
response to organonitrogen compound GO:0010243 246 0.028
myeloid cell differentiation GO:0030099 233 0.027
regulation of cellular response to stress GO:0080135 159 0.027
regulation of protein complex assembly GO:0043254 83 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
body morphogenesis GO:0010171 45 0.027
purine nucleotide biosynthetic process GO:0006164 65 0.027
purine nucleoside biosynthetic process GO:0042451 19 0.027
phosphatidylethanolamine metabolic process GO:0046337 2 0.026
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.026
double strand break repair via homologous recombination GO:0000724 21 0.026
regulation of response to dna damage stimulus GO:2001020 34 0.026
methylation GO:0032259 134 0.026
cellular chemical homeostasis GO:0055082 215 0.026
cation transport GO:0006812 399 0.026
intracellular protein transport GO:0006886 204 0.025
ossification GO:0001503 216 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.025
protein targeting GO:0006605 143 0.025
transmembrane transport GO:0055085 412 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
spermatid development GO:0007286 108 0.025
sequestering of metal ion GO:0051238 19 0.024
response to oxidative stress GO:0006979 123 0.024
calcium ion homeostasis GO:0055074 127 0.024
germ cell development GO:0007281 185 0.024
protein localization to organelle GO:0033365 185 0.024
negative regulation of immune system process GO:0002683 209 0.024
regulation of response to wounding GO:1903034 189 0.024
cellular metal ion homeostasis GO:0006875 151 0.023
oogenesis GO:0048477 56 0.023
maintenance of location GO:0051235 89 0.023
nucleocytoplasmic transport GO:0006913 139 0.023
regulation of peptidase activity GO:0052547 96 0.023
establishment of protein localization to organelle GO:0072594 118 0.023
regulation of protein import into nucleus GO:0042306 52 0.023
regulation of inflammatory response GO:0050727 147 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
development of primary sexual characteristics GO:0045137 143 0.022
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.022
nuclear import GO:0051170 95 0.022
regulation of cell activation GO:0050865 289 0.022
engulfment of apoptotic cell GO:0043652 3 0.021
negative regulation of defense response GO:0031348 77 0.021
cofactor biosynthetic process GO:0051188 41 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
nucleoside monophosphate catabolic process GO:0009125 59 0.020
stem cell differentiation GO:0048863 268 0.020
oocyte axis specification GO:0007309 2 0.020
regulation of vesicle mediated transport GO:0060627 139 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
single organism nuclear import GO:1902593 95 0.020
microtubule cytoskeleton organization GO:0000226 157 0.020
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.020
positive regulation of cell cycle GO:0045787 92 0.020
protein polymerization GO:0051258 57 0.019
positive regulation of kinase activity GO:0033674 155 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.018
peptidyl amino acid modification GO:0018193 336 0.018
purine containing compound biosynthetic process GO:0072522 70 0.018
purine nucleobase biosynthetic process GO:0009113 3 0.018
positive regulation of dna templated transcription elongation GO:0032786 2 0.018
cellular ion homeostasis GO:0006873 165 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
sensory organ morphogenesis GO:0090596 242 0.018
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.018
adenine nucleotide transport GO:0051503 2 0.018
ion transmembrane transport GO:0034220 361 0.017
sequestering of calcium ion GO:0051208 18 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
negative regulation of molecular function GO:0044092 258 0.017
synapse organization GO:0050808 125 0.017
divalent inorganic cation transport GO:0072511 178 0.017
regulation of cysteine type endopeptidase activity GO:2000116 65 0.017
atp metabolic process GO:0046034 75 0.017
cell division GO:0051301 120 0.017
intracellular mrna localization GO:0008298 4 0.017
multicellular organismal aging GO:0010259 24 0.017
chromatin modification GO:0016568 187 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
protein methylation GO:0006479 81 0.016
blood vessel morphogenesis GO:0048514 285 0.016
ribonucleoside monophosphate catabolic process GO:0009158 57 0.016
positive regulation of cell adhesion GO:0045785 80 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
regulation of chromosome organization GO:0033044 83 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
epithelial tube formation GO:0072175 130 0.016
neural tube closure GO:0001843 90 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
nuclear transport GO:0051169 139 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
endomembrane system organization GO:0010256 147 0.015
positive regulation of cytoskeleton organization GO:0051495 49 0.015
lymphocyte proliferation GO:0046651 164 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
gland development GO:0048732 330 0.015
microtubule based process GO:0007017 236 0.015
immune effector process GO:0002252 321 0.015
protein oligomerization GO:0051259 67 0.015
regulation of protein transport GO:0051223 163 0.015
positive regulation of cell development GO:0010720 237 0.014
striated muscle tissue development GO:0014706 293 0.014
cellular lipid metabolic process GO:0044255 323 0.014
signal transduction by p53 class mediator GO:0072331 51 0.014
response to organic cyclic compound GO:0014070 198 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.014
genitalia development GO:0048806 37 0.014
Worm
positive regulation of transferase activity GO:0051347 167 0.014
inflammatory response to antigenic stimulus GO:0002437 30 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
regulation of proteasomal protein catabolic process GO:0061136 46 0.014
cellular response to lipid GO:0071396 145 0.014
regulation of translation GO:0006417 71 0.014
cellular response to hexose stimulus GO:0071331 47 0.014
protein secretion GO:0009306 111 0.014
ribonucleotide biosynthetic process GO:0009260 59 0.014
purine nucleobase metabolic process GO:0006144 4 0.014
b cell activation GO:0042113 161 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.013
leukocyte differentiation GO:0002521 342 0.013
regulation of kinase activity GO:0043549 249 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
negative regulation of intracellular transport GO:0032387 38 0.013
male sex differentiation GO:0046661 109 0.013
primary neural tube formation GO:0014020 95 0.013
fertilization GO:0009566 127 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.013
regulation of protein ubiquitination GO:0031396 52 0.013
cellular response to glucose stimulus GO:0071333 45 0.013
blastocyst development GO:0001824 80 0.012
positive regulation of immune effector process GO:0002699 107 0.012
connective tissue development GO:0061448 179 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.012
negative regulation of response to wounding GO:1903035 77 0.012
regulation of embryonic development GO:0045995 71 0.012
negative regulation of protein processing GO:0010955 79 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
heme metabolic process GO:0042168 16 0.012
negative regulation of cell development GO:0010721 169 0.012
skeletal system development GO:0001501 356 0.012
spindle organization GO:0007051 28 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
rna interference GO:0016246 2 0.012
negative regulation of phospholipid biosynthetic process GO:0071072 1 0.012
response to acid chemical GO:0001101 111 0.012
regionalization GO:0003002 337 0.012
regulation of mapk cascade GO:0043408 248 0.012
carbohydrate homeostasis GO:0033500 128 0.012
regulation of body fluid levels GO:0050878 162 0.012
phagocytosis GO:0006909 66 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
single fertilization GO:0007338 82 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
activation of immune response GO:0002253 138 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
ribonucleoside biosynthetic process GO:0042455 21 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
mitotic cell cycle GO:0000278 195 0.011
anatomical structure homeostasis GO:0060249 145 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
neural tube development GO:0021915 160 0.011
actin filament polymerization GO:0030041 44 0.011
response to drug GO:0042493 75 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
exocytosis GO:0006887 121 0.011
cell maturation GO:0048469 127 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
regulation of actin filament based process GO:0032970 99 0.011
male gonad development GO:0008584 88 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
response to inorganic substance GO:0010035 96 0.010
ventricular cardiac muscle cell differentiation GO:0055012 17 0.010
mrna metabolic process GO:0016071 84 0.010
tube formation GO:0035148 140 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
female gamete generation GO:0007292 74 0.010
cofactor transport GO:0051181 4 0.010
t cell proliferation GO:0042098 120 0.010
nucleotide excision repair GO:0006289 13 0.010
anion transport GO:0006820 177 0.010

Psma4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.050
disease of anatomical entity DOID:7 0 0.050
disease of metabolism DOID:0014667 0 0.036
inherited metabolic disorder DOID:655 0 0.034
immune system cancer DOID:0060083 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014