Mus musculus

0 known processes

Psmb2

proteasome (prosome, macropain) subunit, beta type 2

(Aliases: C7-I,D4Wsu33e,AW108089,AU045357,HC7-I)

Psmb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.823
Fly
nucleoside triphosphate metabolic process GO:0009141 230 0.700
regulation of nucleoside metabolic process GO:0009118 130 0.632
modification dependent macromolecule catabolic process GO:0043632 133 0.343
Yeast
ubiquitin dependent protein catabolic process GO:0006511 129 0.337
Yeast
regulation of hydrolase activity GO:0051336 246 0.283
Yeast
cellular homeostasis GO:0019725 240 0.277
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.277
Yeast
protein catabolic process GO:0030163 221 0.251
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 226 0.250
purine nucleoside metabolic process GO:0042278 241 0.237
ribonucleotide metabolic process GO:0009259 291 0.232
purine ribonucleoside metabolic process GO:0046128 241 0.231
nucleoside metabolic process GO:0009116 246 0.229
regulation of purine nucleotide catabolic process GO:0033121 122 0.223
purine ribonucleotide metabolic process GO:0009150 290 0.197
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.196
Yeast
cellular protein catabolic process GO:0044257 155 0.193
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.171
regulation of nucleotide metabolic process GO:0006140 169 0.163
cellular chemical homeostasis GO:0055082 215 0.151
t cell activation GO:0042110 289 0.147
purine nucleotide catabolic process GO:0006195 211 0.141
ribonucleoside triphosphate metabolic process GO:0009199 220 0.140
ribose phosphate metabolic process GO:0019693 291 0.124
ribonucleoside metabolic process GO:0009119 245 0.119
purine nucleotide metabolic process GO:0006163 302 0.118
localization within membrane GO:0051668 4 0.116
regulation of cellular amino acid metabolic process GO:0006521 5 0.116
dna metabolic process GO:0006259 303 0.115
nucleobase containing small molecule metabolic process GO:0055086 352 0.113
positive regulation of protein modification process GO:0031401 299 0.110
mitochondrial fusion GO:0008053 9 0.106
purine containing compound metabolic process GO:0072521 311 0.105
nucleoside phosphate metabolic process GO:0006753 338 0.104
metal ion homeostasis GO:0055065 189 0.099
nucleotide catabolic process GO:0009166 217 0.097
response to superoxide GO:0000303 16 0.097
proteasome assembly GO:0043248 1 0.095
guanosine containing compound metabolic process GO:1901068 144 0.095
gland development GO:0048732 330 0.095
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.095
extracellular structure organization GO:0043062 148 0.093
cellular ketone metabolic process GO:0042180 84 0.093
cellular ion homeostasis GO:0006873 165 0.091
positive regulation of nucleotide catabolic process GO:0030813 88 0.091
cation homeostasis GO:0055080 212 0.091
cellular metal ion homeostasis GO:0006875 151 0.089
positive regulation of hydrolase activity GO:0051345 148 0.085
Yeast
extracellular matrix organization GO:0030198 147 0.085
regulation of purine nucleotide metabolic process GO:1900542 169 0.083
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.083
positive regulation of nucleoside metabolic process GO:0045979 91 0.079
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.078
macromolecule catabolic process GO:0009057 281 0.076
Yeast
cellular amino acid metabolic process GO:0006520 103 0.075
amine metabolic process GO:0009308 45 0.072
positive regulation of cellular amine metabolic process GO:0033240 5 0.069
t cell proliferation GO:0042098 120 0.069
organophosphate catabolic process GO:0046434 232 0.067
regulation of atp metabolic process GO:1903578 17 0.066
regulation of cellular response to stress GO:0080135 159 0.063
spermatogenesis GO:0007283 284 0.063
male gamete generation GO:0048232 285 0.062
membrane organization GO:0061024 245 0.062
regulation of membrane potential GO:0042391 192 0.062
lymphocyte differentiation GO:0030098 242 0.062
multi multicellular organism process GO:0044706 109 0.060
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.059
cellular macromolecule catabolic process GO:0044265 206 0.059
Yeast
regulation of cellular ketone metabolic process GO:0010565 66 0.059
regulation of mitochondrial membrane potential GO:0051881 17 0.057
regulation of cell motility GO:2000145 236 0.057
cellular protein complex assembly GO:0043623 116 0.056
nucleotide metabolic process GO:0009117 332 0.056
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.055
organonitrogen compound biosynthetic process GO:1901566 192 0.055
regulation of nucleotide catabolic process GO:0030811 122 0.055
cellular amine metabolic process GO:0044106 44 0.055
heterocycle catabolic process GO:0046700 280 0.053
ribonucleotide catabolic process GO:0009261 208 0.053
regulation of cell cycle process GO:0010564 160 0.053
positive regulation of membrane potential GO:0045838 15 0.053
cellular nitrogen compound catabolic process GO:0044270 280 0.053
purine ribonucleoside catabolic process GO:0046130 205 0.051
myeloid cell differentiation GO:0030099 233 0.051
purine nucleoside monophosphate metabolic process GO:0009126 81 0.050
rhythmic process GO:0048511 174 0.048
endomembrane system organization GO:0010256 147 0.048
positive regulation of cellular catabolic process GO:0031331 148 0.048
regulation of gtp catabolic process GO:0033124 113 0.047
positive regulation of proteolysis GO:0045862 85 0.046
Yeast
mitotic cell cycle GO:0000278 195 0.046
positive regulation of gtpase activity GO:0043547 85 0.046
cellular lipid metabolic process GO:0044255 323 0.045
cation transport GO:0006812 399 0.045
leukocyte proliferation GO:0070661 172 0.045
neural tube formation GO:0001841 108 0.045
proteasomal protein catabolic process GO:0010498 98 0.042
Yeast
regulation of cellular amine metabolic process GO:0033238 20 0.042
development of primary sexual characteristics GO:0045137 143 0.042
regulation of organelle organization GO:0033043 289 0.042
nitrogen compound transport GO:0071705 271 0.042
cytoplasmic transport GO:0016482 234 0.041
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
male sex differentiation GO:0046661 109 0.041
regulation of lymphocyte activation GO:0051249 240 0.040
mitotic cytokinesis GO:0000281 4 0.040
glycosyl compound catabolic process GO:1901658 206 0.040
calcium ion transport GO:0006816 159 0.040
purine nucleoside catabolic process GO:0006152 205 0.040
cellular calcium ion homeostasis GO:0006874 119 0.040
calcium ion homeostasis GO:0055074 127 0.040
regulation of t cell activation GO:0050863 170 0.039
glycosyl compound metabolic process GO:1901657 246 0.038
nucleoside triphosphate catabolic process GO:0009143 205 0.038
nucleocytoplasmic transport GO:0006913 139 0.037
leukocyte differentiation GO:0002521 342 0.037
epithelial tube morphogenesis GO:0060562 303 0.037
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.036
Yeast
positive regulation of nucleotide metabolic process GO:0045981 114 0.036
positive regulation of organelle organization GO:0010638 128 0.036
protein modification by small protein conjugation GO:0032446 187 0.036
divalent inorganic cation transport GO:0072511 178 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.034
atp metabolic process GO:0046034 75 0.034
cellular response to lipid GO:0071396 145 0.034
ribonucleoside monophosphate metabolic process GO:0009161 80 0.034
carbohydrate derivative catabolic process GO:1901136 231 0.034
cytokine production GO:0001816 319 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
t cell differentiation GO:0030217 174 0.033
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.033
regulation of transferase activity GO:0051338 263 0.032
ribonucleoside triphosphate catabolic process GO:0009203 199 0.032
protein import into nucleus GO:0006606 95 0.032
extrinsic apoptotic signaling pathway GO:0097191 126 0.032
negative regulation of molecular function GO:0044092 258 0.032
ras protein signal transduction GO:0007265 77 0.031
myosin filament organization GO:0031033 3 0.031
peptidyl amino acid modification GO:0018193 336 0.031
glycerolipid metabolic process GO:0046486 122 0.031
regulation of lymphocyte differentiation GO:0045619 107 0.031
mitotic cell cycle process GO:1903047 159 0.031
stem cell differentiation GO:0048863 268 0.031
divalent inorganic cation homeostasis GO:0072507 138 0.031
microtubule cytoskeleton organization GO:0000226 157 0.030
organophosphate biosynthetic process GO:0090407 122 0.030
regulation of cell migration GO:0030334 219 0.030
reactive oxygen species metabolic process GO:0072593 84 0.030
negative regulation of organelle organization GO:0010639 90 0.029
microtubule based process GO:0007017 236 0.029
lymphocyte proliferation GO:0046651 164 0.029
regulation of leukocyte differentiation GO:1902105 159 0.028
maintenance of location GO:0051235 89 0.028
regulation of cell activation GO:0050865 289 0.028
cell division GO:0051301 120 0.028
epithelial tube formation GO:0072175 130 0.028
glucose homeostasis GO:0042593 128 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
striated muscle myosin thick filament assembly GO:0071688 1 0.027
sensory organ morphogenesis GO:0090596 242 0.027
purine ribonucleotide biosynthetic process GO:0009152 59 0.026
protein processing GO:0016485 163 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.026
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.026
leukocyte mediated immunity GO:0002443 174 0.026
nucleoside catabolic process GO:0009164 206 0.026
protein localization to nucleus GO:0034504 121 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
negative regulation of immune system process GO:0002683 209 0.025
development of primary male sexual characteristics GO:0046546 88 0.025
antigen receptor mediated signaling pathway GO:0050851 64 0.024
modification dependent protein catabolic process GO:0019941 133 0.024
Yeast
regulation of feeding behavior GO:0060259 3 0.024
cellular response to glucose stimulus GO:0071333 45 0.024
myosin filament assembly GO:0031034 2 0.023
purine containing compound catabolic process GO:0072523 213 0.023
organic hydroxy compound biosynthetic process GO:1901617 77 0.023
signal transduction in absence of ligand GO:0038034 55 0.023
regulation of cytoskeleton organization GO:0051493 122 0.023
synaptic transmission GO:0007268 329 0.023
mitochondrion organization GO:0007005 134 0.023
stem cell development GO:0048864 219 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
ribonucleoside catabolic process GO:0042454 206 0.023
nucleotide biosynthetic process GO:0009165 78 0.023
nucleoside monophosphate metabolic process GO:0009123 85 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.022
regulation of t cell differentiation GO:0045580 83 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
alpha beta t cell activation GO:0046631 91 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
locomotory behavior GO:0007626 195 0.022
apoptotic signaling pathway GO:0097190 306 0.022
ameboidal type cell migration GO:0001667 128 0.022
cellular response to hexose stimulus GO:0071331 47 0.022
response to oxygen radical GO:0000305 16 0.022
inorganic ion transmembrane transport GO:0098660 234 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
gtp metabolic process GO:0046039 144 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
endocytosis GO:0006897 168 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
glycerophospholipid metabolic process GO:0006650 71 0.021
exocytosis GO:0006887 121 0.021
positive regulation of cell cycle GO:0045787 92 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
cellular response to oxidative stress GO:0034599 76 0.021
male gonad development GO:0008584 88 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
regulation of lipid metabolic process GO:0019216 118 0.020
immune response activating signal transduction GO:0002757 116 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.020
protein polymerization GO:0051258 57 0.019
regulation of body fluid levels GO:0050878 162 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
dephosphorylation GO:0016311 129 0.019
nucleoside phosphate biosynthetic process GO:1901293 79 0.019
regulation of mapk cascade GO:0043408 248 0.019
cellular transition metal ion homeostasis GO:0046916 32 0.019
cd4 positive alpha beta t cell activation GO:0035710 45 0.019
dna repair GO:0006281 107 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
inorganic cation transmembrane transport GO:0098662 207 0.018
lipid localization GO:0010876 126 0.018
immune effector process GO:0002252 321 0.018
neural tube development GO:0021915 160 0.018
protein localization to organelle GO:0033365 185 0.018
metallo sulfur cluster assembly GO:0031163 3 0.018
mapk cascade GO:0000165 281 0.018
intracellular protein transport GO:0006886 204 0.018
regulation of protein localization to nucleus GO:1900180 60 0.018
stress activated mapk cascade GO:0051403 80 0.017
regulation of secretion by cell GO:1903530 249 0.017
trna wobble uridine modification GO:0002098 2 0.017
gonad development GO:0008406 141 0.017
blastocyst development GO:0001824 80 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
regulation of protein transport GO:0051223 163 0.017
response to monosaccharide GO:0034284 67 0.017
nuclear transport GO:0051169 139 0.017
regulation of protein kinase activity GO:0045859 232 0.017
neural tube closure GO:0001843 90 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
Yeast
mrna processing GO:0006397 63 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
phospholipid metabolic process GO:0006644 87 0.017
striated muscle cell development GO:0055002 125 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.016
cellular response to carbohydrate stimulus GO:0071322 50 0.016
positive regulation of mitotic cell cycle GO:0045931 41 0.016
regulation of homeostatic process GO:0032844 182 0.016
peptidyl serine modification GO:0018209 83 0.016
tube formation GO:0035148 140 0.016
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.016
positive regulation of gtp catabolic process GO:0033126 85 0.016
eye photoreceptor cell differentiation GO:0001754 41 0.016
mrna metabolic process GO:0016071 84 0.016
activation of immune response GO:0002253 138 0.015
skeletal system development GO:0001501 356 0.015
eye photoreceptor cell development GO:0042462 31 0.015
oogenesis GO:0048477 56 0.015
cartilage development GO:0051216 140 0.015
regulation of kinase activity GO:0043549 249 0.015
regulation of protein heterodimerization activity GO:0043497 2 0.015
regulation of anatomical structure size GO:0090066 178 0.015
regulation of protein localization GO:0032880 231 0.015
nuclear import GO:0051170 95 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
regulation of response to wounding GO:1903034 189 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
positive regulation of ion transport GO:0043270 65 0.014
sensory perception GO:0007600 245 0.014
organelle assembly GO:0070925 177 0.014
single organism nuclear import GO:1902593 95 0.014
actin filament polymerization GO:0030041 44 0.014
carbohydrate homeostasis GO:0033500 128 0.014
spindle organization GO:0007051 28 0.014
copii coated vesicle budding GO:0090114 2 0.014
cation transmembrane transport GO:0098655 266 0.014
dna recombination GO:0006310 92 0.014
multicellular organism growth GO:0035264 161 0.014
regulation of cytokine production GO:0001817 266 0.014
ribonucleotide biosynthetic process GO:0009260 59 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
dna dependent dna replication GO:0006261 24 0.013
cell substrate adhesion GO:0031589 130 0.013
t cell receptor signaling pathway GO:0050852 46 0.013
negative regulation of cell cycle GO:0045786 123 0.013
purine ribonucleoside biosynthetic process GO:0046129 19 0.013
iron sulfur cluster assembly GO:0016226 3 0.013
negative regulation of cell motility GO:2000146 61 0.013
negative regulation of binding GO:0051100 39 0.013
mitochondrial dna replication GO:0006264 7 0.013
microtubule organizing center organization GO:0031023 28 0.013
transition metal ion homeostasis GO:0055076 54 0.013
oocyte construction GO:0007308 2 0.013
regulation of actin filament based process GO:0032970 99 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
hydrogen peroxide catabolic process GO:0042744 5 0.013
regulation of peptidyl serine phosphorylation GO:0033135 39 0.013
ossification GO:0001503 216 0.013
protein import GO:0017038 101 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
rna processing GO:0006396 105 0.013
alcohol metabolic process GO:0006066 116 0.013
purine nucleoside biosynthetic process GO:0042451 19 0.013
protein ubiquitination GO:0016567 171 0.012
regulation of cell substrate adhesion GO:0010810 73 0.012
epithelial cell migration GO:0010631 63 0.012
positive regulation of cell migration GO:0030335 109 0.012
muscle cell differentiation GO:0042692 261 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
germ cell development GO:0007281 185 0.012
regulation of cell cycle GO:0051726 281 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
transmembrane transport GO:0055085 412 0.012
female sex differentiation GO:0046660 84 0.012
female gamete generation GO:0007292 74 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
ribonucleoside biosynthetic process GO:0042455 21 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
oocyte axis specification GO:0007309 2 0.012
thymus development GO:0048538 41 0.012
regulation of peptidase activity GO:0052547 96 0.012
Yeast
t cell differentiation in thymus GO:0033077 77 0.012
developmental maturation GO:0021700 193 0.012
regulation of protein maturation GO:1903317 96 0.012
tissue migration GO:0090130 68 0.012
protein targeting GO:0006605 143 0.011
actin cytoskeleton organization GO:0030036 220 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
chromatin modification GO:0016568 187 0.011
regulation of epithelial cell migration GO:0010632 35 0.011
digestive system development GO:0055123 200 0.011
positive regulation of transferase activity GO:0051347 167 0.011
regulation of cellular component size GO:0032535 121 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
single organism cell adhesion GO:0098602 156 0.011
regulation of mitochondrion organization GO:0010821 27 0.011
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.011
aromatic compound catabolic process GO:0019439 286 0.011
covalent chromatin modification GO:0016569 163 0.011
regulation of secretion GO:0051046 274 0.010
oxidation reduction process GO:0055114 342 0.010
positive regulation of peptidase activity GO:0010952 49 0.010
Yeast
organelle localization GO:0051640 179 0.010
organelle fusion GO:0048284 28 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
membrane fusion GO:0061025 38 0.010
inflammatory response GO:0006954 244 0.010
cell adhesion GO:0007155 329 0.010
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.010
placenta development GO:0001890 140 0.010
embryonic epithelial tube formation GO:0001838 130 0.010

Psmb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
central nervous system disease DOID:331 0 0.016
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
inherited metabolic disorder DOID:655 0 0.012
neurodegenerative disease DOID:1289 0 0.011