Mus musculus

30 known processes

Psmb4

proteasome (prosome, macropain) subunit, beta type 4

(Aliases: Pros-27)

Psmb4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 206 0.882
Yeast
cellular response to dna damage stimulus GO:0006974 207 0.841
modification dependent protein catabolic process GO:0019941 133 0.763
Yeast
proteasomal protein catabolic process GO:0010498 98 0.726
Yeast
macromolecule catabolic process GO:0009057 281 0.671
Yeast
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.598
Yeast
ubiquitin dependent protein catabolic process GO:0006511 129 0.534
Yeast
cellular protein catabolic process GO:0044257 155 0.510
Yeast
protein catabolic process GO:0030163 221 0.406
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.391
Yeast
modification dependent macromolecule catabolic process GO:0043632 133 0.325
Yeast
proteasome assembly GO:0043248 1 0.317
Yeast
dna metabolic process GO:0006259 303 0.269
dna repair GO:0006281 107 0.170
nucleoside phosphate metabolic process GO:0006753 338 0.148
nucleoside triphosphate metabolic process GO:0009141 230 0.141
double strand break repair GO:0006302 48 0.134
microtubule cytoskeleton organization GO:0000226 157 0.117
mitotic cell cycle process GO:1903047 159 0.103
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.093
Yeast
nucleotide catabolic process GO:0009166 217 0.088
heterocycle catabolic process GO:0046700 280 0.087
multicellular organismal aging GO:0010259 24 0.082
Worm
spermatogenesis GO:0007283 284 0.078
cellular nitrogen compound catabolic process GO:0044270 280 0.077
purine ribonucleotide metabolic process GO:0009150 290 0.077
apoptotic signaling pathway GO:0097190 306 0.075
male gamete generation GO:0048232 285 0.072
mitotic cell cycle GO:0000278 195 0.068
regulation of mrna splicing via spliceosome GO:0048024 32 0.068
membrane organization GO:0061024 245 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
positive regulation of proteolysis GO:0045862 85 0.065
ribonucleotide catabolic process GO:0009261 208 0.064
chromatin organization GO:0006325 206 0.064
cellular protein complex assembly GO:0043623 116 0.063
Yeast
nucleoside metabolic process GO:0009116 246 0.062
aromatic compound catabolic process GO:0019439 286 0.059
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
spindle organization GO:0007051 28 0.056
gonad development GO:0008406 141 0.054
positive regulation of hydrolase activity GO:0051345 148 0.053
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.052
purine containing compound catabolic process GO:0072523 213 0.051
organelle fission GO:0048285 170 0.049
amine metabolic process GO:0009308 45 0.047
positive regulation of cell death GO:0010942 224 0.047
positive regulation of protein modification process GO:0031401 299 0.047
nucleotide metabolic process GO:0009117 332 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
positive regulation of peptidase activity GO:0010952 49 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
cellular ketone metabolic process GO:0042180 84 0.044
protein localization to organelle GO:0033365 185 0.044
cellular lipid metabolic process GO:0044255 323 0.043
microtubule based process GO:0007017 236 0.042
positive regulation of apoptotic process GO:0043065 217 0.041
cytoplasmic transport GO:0016482 234 0.041
cellular amine metabolic process GO:0044106 44 0.041
mitotic nuclear division GO:0007067 48 0.040
organic cyclic compound catabolic process GO:1901361 295 0.039
oocyte construction GO:0007308 2 0.038
ribonucleoside catabolic process GO:0042454 206 0.038
mapk cascade GO:0000165 281 0.037
protein modification by small protein conjugation GO:0032446 187 0.037
nucleoside catabolic process GO:0009164 206 0.037
nitrogen compound transport GO:0071705 271 0.037
ribonucleoside metabolic process GO:0009119 245 0.037
positive regulation of mapk cascade GO:0043410 170 0.037
purine containing compound metabolic process GO:0072521 311 0.037
organophosphate catabolic process GO:0046434 232 0.037
chromatin modification GO:0016568 187 0.035
cellular response to lipid GO:0071396 145 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.035
purine nucleoside catabolic process GO:0006152 205 0.035
regulation of mapk cascade GO:0043408 248 0.035
transcription from rna polymerase iii promoter GO:0006383 3 0.034
positive regulation of protein phosphorylation GO:0001934 242 0.034
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.034
purine nucleoside metabolic process GO:0042278 241 0.034
reactive oxygen species metabolic process GO:0072593 84 0.033
regulation of cell motility GO:2000145 236 0.033
nucleoside monophosphate catabolic process GO:0009125 59 0.032
regulation of transferase activity GO:0051338 263 0.032
regulation of hydrolase activity GO:0051336 246 0.032
regulation of defense response GO:0031347 233 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.031
peptidyl amino acid modification GO:0018193 336 0.031
negative regulation of defense response GO:0031348 77 0.030
organonitrogen compound catabolic process GO:1901565 264 0.030
spindle assembly involved in mitosis GO:0090307 4 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.029
positive regulation of protein catabolic process GO:0045732 60 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
positive regulation of protein complex assembly GO:0031334 45 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.028
protein localization to membrane GO:0072657 108 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
regulation of cell migration GO:0030334 219 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
oocyte axis specification GO:0007309 2 0.026
organophosphate biosynthetic process GO:0090407 122 0.025
blastocyst development GO:0001824 80 0.025
regulation of proteolysis GO:0030162 164 0.025
carbohydrate homeostasis GO:0033500 128 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
intracellular protein transport GO:0006886 204 0.025
cell division GO:0051301 120 0.025
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.024
gland development GO:0048732 330 0.024
response to organonitrogen compound GO:0010243 246 0.024
protein polymerization GO:0051258 57 0.024
nucleoside phosphate biosynthetic process GO:1901293 79 0.024
positive regulation of cell development GO:0010720 237 0.024
lateral inhibition GO:0046331 1 0.024
nuclear transport GO:0051169 139 0.023
regulation of engulfment of apoptotic cell GO:1901074 2 0.023
response to organic cyclic compound GO:0014070 198 0.023
negative regulation of immune system process GO:0002683 209 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
negative regulation of molecular function GO:0044092 258 0.023
nuclear import GO:0051170 95 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.022
sperm egg recognition GO:0035036 37 0.022
actin cytoskeleton organization GO:0030036 220 0.022
oocyte anterior posterior axis specification GO:0007314 2 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
regulation of t cell activation GO:0050863 170 0.022
regulation of cellular ketone metabolic process GO:0010565 66 0.022
fertilization GO:0009566 127 0.022
sensory organ morphogenesis GO:0090596 242 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
organelle assembly GO:0070925 177 0.021
germ cell development GO:0007281 185 0.021
regulation of protein transport GO:0051223 163 0.021
regulation of protein kinase activity GO:0045859 232 0.021
regulation of system process GO:0044057 200 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
synaptic transmission GO:0007268 329 0.020
regulation of inflammatory response GO:0050727 147 0.020
protein import into nucleus GO:0006606 95 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.020
protein ubiquitination GO:0016567 171 0.020
spindle assembly GO:0051225 13 0.020
regulation of response to wounding GO:1903034 189 0.019
nucleoside monophosphate metabolic process GO:0009123 85 0.019
regulation of cellular response to stress GO:0080135 159 0.019
single organism cell adhesion GO:0098602 156 0.019
protein maturation GO:0051604 176 0.019
positive regulation of endopeptidase activity GO:0010950 43 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
response to inorganic substance GO:0010035 96 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
forebrain development GO:0030900 302 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.019
protein import GO:0017038 101 0.019
intracellular mrna localization GO:0008298 4 0.018
transcription from rna polymerase i promoter GO:0006360 13 0.018
cell maturation GO:0048469 127 0.018
inflammatory response GO:0006954 244 0.018
pole plasm assembly GO:0007315 2 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
transmembrane transport GO:0055085 412 0.018
regulation of endopeptidase activity GO:0052548 89 0.018
cell adhesion GO:0007155 329 0.018
nuclear division GO:0000280 158 0.018
regulation of cell cycle GO:0051726 281 0.018
cellular glucose homeostasis GO:0001678 52 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
multi multicellular organism process GO:0044706 109 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
regulation of peptidase activity GO:0052547 96 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
regulation of kinase activity GO:0043549 249 0.017
meiotic cell cycle GO:0051321 122 0.017
cellular chemical homeostasis GO:0055082 215 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
divalent inorganic cation transport GO:0072511 178 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
cytokine production GO:0001816 319 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
positive regulation of kinase activity GO:0033674 155 0.016
regulation of protein catabolic process GO:0042176 108 0.016
oogenesis GO:0048477 56 0.016
positive regulation of transferase activity GO:0051347 167 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
regulation of body fluid levels GO:0050878 162 0.016
mitotic spindle organization GO:0007052 10 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
ribonucleoside monophosphate catabolic process GO:0009158 57 0.015
leukocyte proliferation GO:0070661 172 0.015
response to alcohol GO:0097305 48 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
mitochondrion organization GO:0007005 134 0.015
lymphocyte proliferation GO:0046651 164 0.015
circulatory system process GO:0003013 197 0.015
muscle system process GO:0003012 141 0.015
protein acylation GO:0043543 64 0.015
cellular homeostasis GO:0019725 240 0.015
signal transduction in absence of ligand GO:0038034 55 0.015
protein targeting GO:0006605 143 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
regulation of cell activation GO:0050865 289 0.014
positive regulation of dna templated transcription elongation GO:0032786 2 0.014
regulation of hormone levels GO:0010817 211 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
cellular response to hexose stimulus GO:0071331 47 0.014
stem cell differentiation GO:0048863 268 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
placenta development GO:0001890 140 0.014
regulation of intracellular transport GO:0032386 159 0.014
rna interference GO:0016246 2 0.014
aldehyde catabolic process GO:0046185 4 0.014
regulation of protein complex assembly GO:0043254 83 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
establishment of protein localization to organelle GO:0072594 118 0.013
regulation of organelle organization GO:0033043 289 0.013
cation transport GO:0006812 399 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.013
small molecule biosynthetic process GO:0044283 132 0.013
cation transmembrane transport GO:0098655 266 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
erk1 and erk2 cascade GO:0070371 77 0.013
epithelial cell proliferation GO:0050673 174 0.013
response to oxidative stress GO:0006979 123 0.013
response to acid chemical GO:0001101 111 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
ameboidal type cell migration GO:0001667 128 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
telencephalon development GO:0021537 186 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
t cell proliferation GO:0042098 120 0.012
cellular response to carbohydrate stimulus GO:0071322 50 0.012
camera type eye development GO:0043010 266 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.012
dna recombination GO:0006310 92 0.012
rna splicing GO:0008380 54 0.012
organic acid biosynthetic process GO:0016053 86 0.012
endocytosis GO:0006897 168 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
extracellular structure organization GO:0043062 148 0.011
protein localization to nucleus GO:0034504 121 0.011
positive regulation of cellular protein catabolic process GO:1903364 34 0.011
regionalization GO:0003002 337 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
maintenance of location GO:0051235 89 0.011
response to lipopolysaccharide GO:0032496 128 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
regulation of protein targeting GO:1903533 61 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
leukocyte differentiation GO:0002521 342 0.011
blood circulation GO:0008015 195 0.011
cellular response to glucose stimulus GO:0071333 45 0.011
regulation of protein localization to nucleus GO:1900180 60 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
spermatid differentiation GO:0048515 115 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
calcium ion transport GO:0006816 159 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
calcium ion homeostasis GO:0055074 127 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
female gamete generation GO:0007292 74 0.011
protein processing GO:0016485 163 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
dephosphorylation GO:0016311 129 0.010
microtubule organizing center organization GO:0031023 28 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
regulation of multi organism process GO:0043900 111 0.010
single organism nuclear import GO:1902593 95 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
glucose homeostasis GO:0042593 128 0.010
t cell activation GO:0042110 289 0.010
atp catabolic process GO:0006200 55 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
meiotic nuclear division GO:0007126 115 0.010
protein dna complex subunit organization GO:0071824 28 0.010
spermatid development GO:0007286 108 0.010
cell fate commitment GO:0045165 210 0.010
negative regulation of cell development GO:0010721 169 0.010

Psmb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
central nervous system disease DOID:331 0 0.018