Mus musculus

0 known processes

Psmc2

proteasome (prosome, macropain) 26S subunit, ATPase 2

Psmc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasomal protein catabolic process GO:0010498 98 0.954
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.926
ubiquitin dependent protein catabolic process GO:0006511 129 0.877
Human Yeast
modification dependent macromolecule catabolic process GO:0043632 133 0.872
Human Yeast
protein catabolic process GO:0030163 221 0.864
Human Yeast
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.860
Yeast
modification dependent protein catabolic process GO:0019941 133 0.840
Human Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.838
Human Yeast
spindle assembly involved in mitosis GO:0090307 4 0.838
proteasome assembly GO:0043248 1 0.825
Yeast
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.772
cellular macromolecule catabolic process GO:0044265 206 0.726
Human Yeast
macromolecule catabolic process GO:0009057 281 0.696
Human Yeast
cellular protein catabolic process GO:0044257 155 0.682
Human Yeast
mitotic cell cycle GO:0000278 195 0.613
mitotic cell cycle process GO:1903047 159 0.591
cellular response to dna damage stimulus GO:0006974 207 0.580
Fly
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.574
Yeast
dna metabolic process GO:0006259 303 0.523
sperm egg recognition GO:0035036 37 0.404
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.380
fertilization GO:0009566 127 0.373
gonad development GO:0008406 141 0.270
mitotic nuclear division GO:0007067 48 0.233
protein modification by small protein removal GO:0070646 21 0.194
positive regulation of hydrolase activity GO:0051345 148 0.193
organelle fission GO:0048285 170 0.191
nuclear division GO:0000280 158 0.175
protein modification by small protein conjugation or removal GO:0070647 207 0.164
cellular protein complex assembly GO:0043623 116 0.148
Yeast
protein modification by small protein conjugation GO:0032446 187 0.148
negative regulation of protein metabolic process GO:0051248 282 0.147
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.141
camera type eye development GO:0043010 266 0.140
ribonucleoside monophosphate catabolic process GO:0009158 57 0.139
Human
positive regulation of dna templated transcription elongation GO:0032786 2 0.128
dna templated transcription initiation GO:0006352 13 0.127
Yeast
regulation of protein maturation GO:1903317 96 0.120
regulation of proteolysis GO:0030162 164 0.120
regulation of cellular catabolic process GO:0031329 242 0.117
binding of sperm to zona pellucida GO:0007339 34 0.113
spindle organization GO:0007051 28 0.113
purine ribonucleotide metabolic process GO:0009150 290 0.109
Human
regulation of hydrolase activity GO:0051336 246 0.108
single fertilization GO:0007338 82 0.108
organelle assembly GO:0070925 177 0.101
dna repair GO:0006281 107 0.101
protein refolding GO:0042026 1 0.099
protein import GO:0017038 101 0.097
regulation of peptidase activity GO:0052547 96 0.096
regulation of cell cycle process GO:0010564 160 0.095
regulation of endopeptidase activity GO:0052548 89 0.095
ribonucleoside triphosphate catabolic process GO:0009203 199 0.095
Human
positive regulation of proteolysis GO:0045862 85 0.094
purine nucleoside catabolic process GO:0006152 205 0.090
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.090
posttranscriptional regulation of gene expression GO:0010608 155 0.086
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.085
Yeast
maternal determination of anterior posterior axis embryo GO:0008358 2 0.084
protein deubiquitination GO:0016579 19 0.081
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.081
protein ubiquitination GO:0016567 171 0.080
purine nucleotide catabolic process GO:0006195 211 0.080
Human
negative regulation of protein maturation GO:1903318 79 0.079
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.077
Human
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.077
Yeast
protein import into nucleus GO:0006606 95 0.076
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.075
pore complex assembly GO:0046931 3 0.074
negative regulation of cell proliferation GO:0008285 296 0.073
spermatogenesis GO:0007283 284 0.073
purine ribonucleoside metabolic process GO:0046128 241 0.073
Human
organophosphate catabolic process GO:0046434 232 0.073
Human
protein localization to nucleus GO:0034504 121 0.071
regulation of mitotic cell cycle phase transition GO:1901990 73 0.067
chromatin organization GO:0006325 206 0.067
cellular nitrogen compound catabolic process GO:0044270 280 0.066
Human
regulation of protein processing GO:0070613 96 0.062
oocyte construction GO:0007308 2 0.061
spermatid differentiation GO:0048515 115 0.060
nucleotide catabolic process GO:0009166 217 0.060
Human
protein processing GO:0016485 163 0.059
nuclear import GO:0051170 95 0.059
cell division GO:0051301 120 0.056
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.056
development of primary sexual characteristics GO:0045137 143 0.055
regulation of proteasomal protein catabolic process GO:0061136 46 0.054
positive regulation of endopeptidase activity GO:0010950 43 0.053
negative regulation of protein catabolic process GO:0042177 36 0.053
protein acylation GO:0043543 64 0.051
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.051
regulation of cellular protein catabolic process GO:1903362 61 0.051
regulation of protein catabolic process GO:0042176 108 0.051
Yeast
negative regulation of proteolysis GO:0045861 74 0.050
intracellular protein transport GO:0006886 204 0.048
oocyte anterior posterior axis specification GO:0007314 2 0.048
regulation of protein targeting GO:1903533 61 0.048
rna interference GO:0016246 2 0.048
toxin transport GO:1901998 38 0.048
male gamete generation GO:0048232 285 0.048
cell cell recognition GO:0009988 44 0.046
protein stabilization GO:0050821 25 0.046
negative regulation of cellular protein catabolic process GO:1903363 22 0.045
nuclear transport GO:0051169 139 0.045
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.045
histone acetylation GO:0016573 41 0.044
double strand break repair GO:0006302 48 0.044
genitalia development GO:0048806 37 0.044
heterocycle catabolic process GO:0046700 280 0.043
Human
regulation of inclusion body assembly GO:0090083 1 0.043
regulation of protein stability GO:0031647 52 0.041
protein polymerization GO:0051258 57 0.041
negative regulation of cell development GO:0010721 169 0.041
positive regulation of peptidase activity GO:0010952 49 0.041
chromatin modification GO:0016568 187 0.040
protein maturation GO:0051604 176 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.039
Human
purine nucleoside monophosphate catabolic process GO:0009128 58 0.038
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
Human
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.038
Yeast
microtubule cytoskeleton organization GO:0000226 157 0.038
regulation of cell cycle GO:0051726 281 0.038
mitotic cytokinesis GO:0000281 4 0.038
spindle assembly GO:0051225 13 0.038
protein targeting GO:0006605 143 0.037
regulation of mitotic cell cycle GO:0007346 126 0.037
glycosyl compound metabolic process GO:1901657 246 0.036
Human
mitotic spindle organization GO:0007052 10 0.036
regulation of ion transmembrane transport GO:0034765 119 0.036
dna recombination GO:0006310 92 0.035
embryonic organ morphogenesis GO:0048562 276 0.035
mapk cascade GO:0000165 281 0.035
synaptic transmission GO:0007268 329 0.034
establishment of protein localization to organelle GO:0072594 118 0.034
regulation of transmembrane transport GO:0034762 128 0.034
nucleoside monophosphate catabolic process GO:0009125 59 0.034
Human
protein localization to organelle GO:0033365 185 0.034
negative regulation of molecular function GO:0044092 258 0.034
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.034
atp catabolic process GO:0006200 55 0.033
Human
protein dna complex subunit organization GO:0071824 28 0.033
Yeast
molting cycle GO:0042303 90 0.033
purine containing compound catabolic process GO:0072523 213 0.032
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
Human
positive regulation of cell death GO:0010942 224 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.030
Human
oocyte axis specification GO:0007309 2 0.030
transmembrane transport GO:0055085 412 0.029
regulation of ion transport GO:0043269 215 0.029
regulation of receptor activity GO:0010469 41 0.029
regulation of intracellular transport GO:0032386 159 0.028
microtubule based process GO:0007017 236 0.028
chromosome segregation GO:0007059 48 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
oocyte differentiation GO:0009994 35 0.027
purine containing compound metabolic process GO:0072521 311 0.026
Human
ribonucleotide catabolic process GO:0009261 208 0.026
Human
regulation of cellular component biogenesis GO:0044087 181 0.026
Yeast
nucleoside catabolic process GO:0009164 206 0.026
Human
multicellular organismal aging GO:0010259 24 0.026
Worm
positive regulation of cellular component biogenesis GO:0044089 94 0.026
Yeast
response to organonitrogen compound GO:0010243 246 0.025
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.025
sensory organ morphogenesis GO:0090596 242 0.025
organic acid biosynthetic process GO:0016053 86 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
Human
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 6 0.025
Yeast
positive regulation of protein modification process GO:0031401 299 0.025
positive regulation of protein catabolic process GO:0045732 60 0.024
Yeast
peptidyl amino acid modification GO:0018193 336 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of chromosome organization GO:0033044 83 0.024
regulation of establishment of protein localization GO:0070201 181 0.024
sperm individualization GO:0007291 1 0.024
determination of adult lifespan GO:0008340 11 0.023
Worm
negative regulation of cellular catabolic process GO:0031330 47 0.023
cell recognition GO:0008037 83 0.023
internal protein amino acid acetylation GO:0006475 42 0.023
ribonucleoside monophosphate metabolic process GO:0009161 80 0.023
Human
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.023
regulation of cell cycle phase transition GO:1901987 77 0.022
posttranscriptional gene silencing GO:0016441 10 0.022
internal peptidyl lysine acetylation GO:0018393 42 0.022
single organism nuclear import GO:1902593 95 0.022
regulation of stem cell differentiation GO:2000736 50 0.022
regulation of cysteine type endopeptidase activity GO:2000116 65 0.022
blastocyst development GO:0001824 80 0.022
cell maturation GO:0048469 127 0.022
ribonucleoside metabolic process GO:0009119 245 0.021
Human
regulation of anion transport GO:0044070 27 0.021
photoreceptor cell development GO:0042461 40 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
Human
carboxylic acid biosynthetic process GO:0046394 86 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
negative regulation of protein processing GO:0010955 79 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
regulation of kinase activity GO:0043549 249 0.020
single organism cell adhesion GO:0098602 156 0.019
positive regulation of transferase activity GO:0051347 167 0.019
negative regulation of cell cycle phase transition GO:1901988 48 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
Human
regulation of protein complex assembly GO:0043254 83 0.019
Yeast
nucleotide metabolic process GO:0009117 332 0.019
Human
protein methylation GO:0006479 81 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
single organismal cell cell adhesion GO:0016337 131 0.019
regulation of protein ubiquitination GO:0031396 52 0.019
aromatic compound catabolic process GO:0019439 286 0.019
Human
purine ribonucleoside catabolic process GO:0046130 205 0.019
Human
positive regulation of cellular protein catabolic process GO:1903364 34 0.018
stem cell differentiation GO:0048863 268 0.018
protein folding GO:0006457 28 0.018
cation transmembrane transport GO:0098655 266 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.018
Human
dna integrity checkpoint GO:0031570 28 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.017
peptidyl lysine modification GO:0018205 77 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
Human
nucleoside phosphate catabolic process GO:1901292 222 0.017
Human
ion transmembrane transport GO:0034220 361 0.017
regulation of mitosis GO:0007088 29 0.017
spermatid development GO:0007286 108 0.017
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.017
embryonic axis specification GO:0000578 30 0.017
regulation of cell division GO:0051302 76 0.017
regulation of transferase activity GO:0051338 263 0.017
regulation of protein kinase activity GO:0045859 232 0.017
positive regulation of mapk cascade GO:0043410 170 0.016
leukocyte migration GO:0050900 124 0.016
stress activated mapk cascade GO:0051403 80 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.016
palate development GO:0060021 76 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
Human
carbohydrate derivative catabolic process GO:1901136 231 0.015
Human
leukocyte proliferation GO:0070661 172 0.015
locomotory behavior GO:0007626 195 0.015
regulation of cellular amino acid metabolic process GO:0006521 5 0.015
regulation of nuclear division GO:0051783 56 0.015
developmental programmed cell death GO:0010623 41 0.015
methylation GO:0032259 134 0.015
axonogenesis GO:0007409 274 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
negative regulation of mitotic cell cycle GO:0045930 58 0.015
regulation of protein transport GO:0051223 163 0.015
anion transport GO:0006820 177 0.015
macromolecule methylation GO:0043414 120 0.015
cytoplasmic transport GO:0016482 234 0.014
negative regulation of endopeptidase activity GO:0010951 44 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
germ cell development GO:0007281 185 0.014
neural tube formation GO:0001841 108 0.014
t cell proliferation GO:0042098 120 0.014
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.014
Yeast
peptidyl lysine acetylation GO:0018394 45 0.014
negative regulation of cell cycle GO:0045786 123 0.014
oogenesis GO:0048477 56 0.014
regulation of protein localization to nucleus GO:1900180 60 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
recombinational repair GO:0000725 21 0.013
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
Human
lateral inhibition GO:0046331 1 0.013
nucleotide excision repair GO:0006289 13 0.013
positive regulation of protein complex assembly GO:0031334 45 0.013
Yeast
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
respiratory system development GO:0060541 190 0.013
regulation of cell growth GO:0001558 91 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
extracellular structure organization GO:0043062 148 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
oocyte development GO:0048599 33 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
chromosome separation GO:0051304 14 0.013
gene silencing GO:0016458 38 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
regulation of transporter activity GO:0032409 57 0.012
cell cycle checkpoint GO:0000075 47 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
Human
calcium ion transport GO:0006816 159 0.012
regulation of body fluid levels GO:0050878 162 0.012
regulation of inflammatory response GO:0050727 147 0.012
dna damage checkpoint GO:0000077 26 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
Human
negative regulation of intracellular signal transduction GO:1902532 167 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
protein alkylation GO:0008213 81 0.012
rna splicing GO:0008380 54 0.012
positive regulation of protein localization to nucleus GO:1900182 30 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
Human
regulation of dna templated transcription initiation GO:2000142 7 0.012
Yeast
cytokinesis GO:0000910 17 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
dephosphorylation GO:0016311 129 0.011
double strand break repair via homologous recombination GO:0000724 21 0.011
t cell activation GO:0042110 289 0.011
cytoplasmic microtubule organization GO:0031122 14 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
regulation of membrane potential GO:0042391 192 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
cell fate commitment GO:0045165 210 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
forebrain development GO:0030900 302 0.011
regulation of cellular ketone metabolic process GO:0010565 66 0.011
cellular amine metabolic process GO:0044106 44 0.011
regulation of protein binding GO:0043393 60 0.011
gene silencing by rna GO:0031047 19 0.011
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.011
negative regulation of retinal cell programmed cell death GO:0046671 2 0.011
dna templated transcription elongation GO:0006354 13 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
epithelial cell proliferation GO:0050673 174 0.011
positive regulation of dna templated transcription initiation GO:2000144 5 0.011
Yeast
regulation of organelle organization GO:0033043 289 0.011
embryonic eye morphogenesis GO:0048048 29 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
female gamete generation GO:0007292 74 0.010
regionalization GO:0003002 337 0.010
response to peptide hormone GO:0043434 127 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
negative regulation of alcohol biosynthetic process GO:1902931 4 0.010

Psmc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.045
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
neuropathy DOID:870 0 0.045