Mus musculus

0 known processes

Psmd4

proteasome (prosome, macropain) 26S subunit, non-ATPase, 4

(Aliases: angiocidin,Af1,Mcb1)

Psmd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasome assembly GO:0043248 1 0.997
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.990
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.986
protein catabolic process GO:0030163 221 0.984
Yeast Worm
proteasomal protein catabolic process GO:0010498 98 0.983
modification dependent macromolecule catabolic process GO:0043632 133 0.979
Yeast Worm
cellular protein catabolic process GO:0044257 155 0.965
Yeast Worm
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.950
macromolecule catabolic process GO:0009057 281 0.910
Yeast Worm
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.909
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.902
modification dependent protein catabolic process GO:0019941 133 0.896
Yeast Worm
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.871
Yeast Worm
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.859
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.802
cellular macromolecule catabolic process GO:0044265 206 0.703
Yeast Worm
cellular response to dna damage stimulus GO:0006974 207 0.690
Fly
ubiquitin dependent protein catabolic process GO:0006511 129 0.647
Yeast Worm
organelle fission GO:0048285 170 0.595
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.595
purine nucleoside metabolic process GO:0042278 241 0.593
blastocyst development GO:0001824 80 0.563
regulation of inclusion body assembly GO:0090083 1 0.539
rna catabolic process GO:0006401 29 0.522
purine ribonucleotide metabolic process GO:0009150 290 0.518
regulation of dna templated transcription initiation GO:2000142 7 0.512
positive regulation of dna templated transcription initiation GO:2000144 5 0.504
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.496
nuclear division GO:0000280 158 0.445
purine ribonucleoside metabolic process GO:0046128 241 0.424
protein dna complex subunit organization GO:0071824 28 0.401
positive regulation of cellular component biogenesis GO:0044089 94 0.366
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.364
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.360
mitotic spindle organization GO:0007052 10 0.319
mitotic cell cycle GO:0000278 195 0.291
carbohydrate derivative catabolic process GO:1901136 231 0.291
regulation of protein complex assembly GO:0043254 83 0.290
positive regulation of protein complex assembly GO:0031334 45 0.288
ribonucleoside monophosphate metabolic process GO:0009161 80 0.281
microtubule based process GO:0007017 236 0.269
ribonucleoside monophosphate catabolic process GO:0009158 57 0.254
ribonucleoside metabolic process GO:0009119 245 0.252
protein modification by small protein conjugation GO:0032446 187 0.251
Fly
purine nucleoside triphosphate catabolic process GO:0009146 203 0.219
protein ubiquitination GO:0016567 171 0.215
Fly
dna metabolic process GO:0006259 303 0.200
nucleoside metabolic process GO:0009116 246 0.198
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 6 0.198
ribonucleotide catabolic process GO:0009261 208 0.193
nucleoside triphosphate metabolic process GO:0009141 230 0.185
purine containing compound metabolic process GO:0072521 311 0.182
positive regulation of dna templated transcription elongation GO:0032786 2 0.173
gonad development GO:0008406 141 0.169
purine nucleoside catabolic process GO:0006152 205 0.160
atp catabolic process GO:0006200 55 0.158
purine nucleotide metabolic process GO:0006163 302 0.156
atp metabolic process GO:0046034 75 0.154
dna templated transcription initiation GO:0006352 13 0.152
cellular protein complex assembly GO:0043623 116 0.149
nucleotide catabolic process GO:0009166 217 0.146
purine nucleoside triphosphate metabolic process GO:0009144 226 0.135
nucleoside phosphate catabolic process GO:1901292 222 0.131
positive regulation of hydrolase activity GO:0051345 148 0.130
ribose phosphate metabolic process GO:0019693 291 0.130
positive regulation of nucleotide catabolic process GO:0030813 88 0.126
ovarian follicle development GO:0001541 40 0.125
purine containing compound catabolic process GO:0072523 213 0.119
mitotic cell cycle process GO:1903047 159 0.119
spindle organization GO:0007051 28 0.116
protein modification by small protein removal GO:0070646 21 0.115
nucleoside monophosphate metabolic process GO:0009123 85 0.113
organelle assembly GO:0070925 177 0.104
ribonucleoside triphosphate catabolic process GO:0009203 199 0.102
cytoplasmic translational initiation GO:0002183 3 0.102
regulation of cellular component biogenesis GO:0044087 181 0.099
ribonucleotide metabolic process GO:0009259 291 0.095
mitotic cytokinesis GO:0000281 4 0.093
nucleoside monophosphate catabolic process GO:0009125 59 0.092
nucleoside catabolic process GO:0009164 206 0.090
protein deubiquitination GO:0016579 19 0.088
purine nucleotide catabolic process GO:0006195 211 0.088
regulation of organelle organization GO:0033043 289 0.087
membrane fusion GO:0061025 38 0.084
regulation of protein catabolic process GO:0042176 108 0.084
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.082
exosomal secretion GO:1990182 1 0.078
positive regulation of cellular catabolic process GO:0031331 148 0.076
heterocycle catabolic process GO:0046700 280 0.076
nucleoside triphosphate catabolic process GO:0009143 205 0.074
regulation of chromosome organization GO:0033044 83 0.074
purine nucleoside monophosphate metabolic process GO:0009126 81 0.073
positive regulation of protein catabolic process GO:0045732 60 0.072
multicellular organismal aging GO:0010259 24 0.070
Worm
cell division GO:0051301 120 0.070
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.069
glycosyl compound catabolic process GO:1901658 206 0.066
glycosyl compound metabolic process GO:1901657 246 0.063
copii coated vesicle budding GO:0090114 2 0.063
spindle assembly involved in mitosis GO:0090307 4 0.062
negative regulation of neuron apoptotic process GO:0043524 92 0.062
mitochondrial fusion GO:0008053 9 0.061
purine ribonucleotide catabolic process GO:0009154 208 0.061
positive regulation of gtpase activity GO:0043547 85 0.060
response to misfolded protein GO:0051788 5 0.055
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.055
chromatin organization GO:0006325 206 0.055
ovulation cycle GO:0042698 59 0.054
organophosphate catabolic process GO:0046434 232 0.054
protein polymerization GO:0051258 57 0.054
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.053
mitotic nuclear division GO:0007067 48 0.053
regulation of actin filament polymerization GO:0030833 38 0.052
positive regulation of protein modification process GO:0031401 299 0.052
regulation of hydrolase activity GO:0051336 246 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.049
regulation of feeding behavior GO:0060259 3 0.049
mitotic sister chromatid segregation GO:0000070 14 0.048
aromatic compound catabolic process GO:0019439 286 0.048
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.048
amine metabolic process GO:0009308 45 0.047
neural tube formation GO:0001841 108 0.045
positive regulation of proteolysis GO:0045862 85 0.044
meiotic cell cycle process GO:1903046 77 0.044
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.043
female sex differentiation GO:0046660 84 0.043
inner cell mass cell proliferation GO:0001833 15 0.042
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.042
meiosis i GO:0007127 60 0.042
sister chromatid segregation GO:0000819 20 0.042
dna repair GO:0006281 107 0.041
regulation of cellular protein catabolic process GO:1903362 61 0.041
cellular response to misfolded protein GO:0071218 5 0.040
positive regulation of cellular protein catabolic process GO:1903364 34 0.040
negative regulation of protein metabolic process GO:0051248 282 0.039
regulation of cell cycle process GO:0010564 160 0.039
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.039
microtubule cytoskeleton organization GO:0000226 157 0.039
meiotic cell cycle GO:0051321 122 0.039
regulation of cellular catabolic process GO:0031329 242 0.038
synaptic transmission GO:0007268 329 0.037
t cell activation GO:0042110 289 0.037
trna wobble uridine modification GO:0002098 2 0.037
positive regulation of protein phosphorylation GO:0001934 242 0.037
t cell proliferation GO:0042098 120 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
development of primary sexual characteristics GO:0045137 143 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
purine nucleoside monophosphate catabolic process GO:0009128 58 0.035
inclusion body assembly GO:0070841 3 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
cellular amino acid metabolic process GO:0006520 103 0.033
regulation of proteasomal protein catabolic process GO:0061136 46 0.033
cellular ketone metabolic process GO:0042180 84 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
meiotic nuclear division GO:0007126 115 0.032
connective tissue development GO:0061448 179 0.032
translational initiation GO:0006413 24 0.031
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.031
chromatin modification GO:0016568 187 0.029
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.028
double strand break repair GO:0006302 48 0.028
regulation of cell division GO:0051302 76 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.028
negative regulation of proteolysis GO:0045861 74 0.028
positive regulation of nucleoside metabolic process GO:0045979 91 0.027
histone modification GO:0016570 159 0.027
nucleotide metabolic process GO:0009117 332 0.026
dna templated transcription elongation GO:0006354 13 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
peptidyl amino acid modification GO:0018193 336 0.026
chromosome segregation GO:0007059 48 0.025
Fly
chromatin remodeling GO:0006338 32 0.025
regulation of proteolysis GO:0030162 164 0.024
regulation of protein ubiquitination GO:0031396 52 0.023
Fly
eye photoreceptor cell development GO:0042462 31 0.023
organelle fusion GO:0048284 28 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.022
Fly
gliogenesis GO:0042063 141 0.022
organonitrogen compound catabolic process GO:1901565 264 0.021
response to endoplasmic reticulum stress GO:0034976 53 0.021
chromosome separation GO:0051304 14 0.021
stem cell differentiation GO:0048863 268 0.021
sperm egg recognition GO:0035036 37 0.020
cellular amine metabolic process GO:0044106 44 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
negative regulation of cellular protein catabolic process GO:1903363 22 0.020
male gamete generation GO:0048232 285 0.020
Worm
guanosine containing compound catabolic process GO:1901069 144 0.020
cartilage development GO:0051216 140 0.019
translesion synthesis GO:0019985 1 0.019
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.019
regulation of protein deubiquitination GO:0090085 1 0.019
lipid localization GO:0010876 126 0.019
exocytosis GO:0006887 121 0.019
regulation of mitotic sister chromatid segregation GO:0033047 12 0.019
ras protein signal transduction GO:0007265 77 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.018
response to peptide hormone GO:0043434 127 0.018
protein maturation GO:0051604 176 0.018
protein processing GO:0016485 163 0.018
regulation of translation GO:0006417 71 0.017
positive regulation of endopeptidase activity GO:0010950 43 0.017
regulation of nuclear division GO:0051783 56 0.017
cell adhesion GO:0007155 329 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
camera type eye development GO:0043010 266 0.017
fertilization GO:0009566 127 0.017
lymphocyte differentiation GO:0030098 242 0.017
mapk cascade GO:0000165 281 0.016
negative regulation of protein catabolic process GO:0042177 36 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.016
positive regulation of organelle organization GO:0010638 128 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
female gonad development GO:0008585 71 0.016
dna recombination GO:0006310 92 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
Fly
regulation of transferase activity GO:0051338 263 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
non recombinational repair GO:0000726 10 0.016
protein acylation GO:0043543 64 0.016
protein secretion GO:0009306 111 0.015
covalent chromatin modification GO:0016569 163 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
calcium ion transport GO:0006816 159 0.015
regulation of membrane potential GO:0042391 192 0.015
regulation of protein maturation GO:1903317 96 0.015
divalent inorganic cation transport GO:0072511 178 0.015
spermatogenesis GO:0007283 284 0.015
Worm
cytokine production GO:0001816 319 0.015
development of primary female sexual characteristics GO:0046545 73 0.015
regulation of receptor activity GO:0010469 41 0.015
blood vessel morphogenesis GO:0048514 285 0.015
positive regulation of peptidase activity GO:0010952 49 0.015
sensory organ morphogenesis GO:0090596 242 0.014
regulation of inflammatory response GO:0050727 147 0.014
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.014
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
oocyte construction GO:0007308 2 0.014
spermatid differentiation GO:0048515 115 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
leukocyte differentiation GO:0002521 342 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of actin filament based process GO:0032970 99 0.014
rhythmic process GO:0048511 174 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.013
trna metabolic process GO:0006399 11 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
mitotic sister chromatid separation GO:0051306 9 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
oocyte axis specification GO:0007309 2 0.013
cytokinetic process GO:0032506 2 0.013
organelle membrane fusion GO:0090174 1 0.013
skeletal system development GO:0001501 356 0.013
response to organonitrogen compound GO:0010243 246 0.013
ossification GO:0001503 216 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
endomembrane system organization GO:0010256 147 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
positive regulation of transferase activity GO:0051347 167 0.012
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
ameboidal type cell migration GO:0001667 128 0.012
myeloid cell differentiation GO:0030099 233 0.012
actin filament organization GO:0007015 113 0.012
positive regulation of growth hormone receptor signaling pathway GO:0060399 3 0.012
leukocyte migration GO:0050900 124 0.012
endocytosis GO:0006897 168 0.012
alpha beta t cell activation GO:0046631 91 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.012
extracellular matrix organization GO:0030198 147 0.012
norepinephrine secretion GO:0048243 2 0.012
maintenance of location GO:0051235 89 0.011
oogenesis GO:0048477 56 0.011
negative regulation of translational initiation GO:0045947 4 0.011
cellular homeostasis GO:0019725 240 0.011
negative regulation of neuron death GO:1901215 98 0.011
response to transforming growth factor beta GO:0071559 88 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
extracellular structure organization GO:0043062 148 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
regulation of translational elongation GO:0006448 4 0.011
negative regulation of protein maturation GO:1903318 79 0.011
mature dendritic cell differentiation GO:0097029 3 0.011
t cell differentiation in thymus GO:0033077 77 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
regulation of cell activation GO:0050865 289 0.011
regulation of cell adhesion GO:0030155 154 0.010
organelle localization GO:0051640 179 0.010
astrocyte development GO:0014002 12 0.010
negative regulation of protein processing GO:0010955 79 0.010
response to inorganic substance GO:0010035 96 0.010
protein neddylation GO:0045116 1 0.010

Psmd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.020
disease of anatomical entity DOID:7 0 0.020
charcot marie tooth disease DOID:10595 0 0.020
nervous system disease DOID:863 0 0.020
neuropathy DOID:870 0 0.020
disease of metabolism DOID:0014667 0 0.013
central nervous system disease DOID:331 0 0.011