Mus musculus

0 known processes

Psme3

proteaseome (prosome, macropain) 28 subunit, 3

(Aliases: AA410043,PA28gamma,REGgamma,Ki,AU020960,pa28g)

Psme3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.173
negative regulation of cell cycle GO:0045786 123 0.124
amine metabolic process GO:0009308 45 0.116
mitochondrion organization GO:0007005 134 0.111
regulation of cellular catabolic process GO:0031329 242 0.104
Human
translation GO:0006412 93 0.098
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.096
small gtpase mediated signal transduction GO:0007264 97 0.081
regionalization GO:0003002 337 0.080
modification dependent protein catabolic process GO:0019941 133 0.077
cytoplasmic transport GO:0016482 234 0.075
negative regulation of protein metabolic process GO:0051248 282 0.074
regulation of establishment of protein localization GO:0070201 181 0.071
response to oxidative stress GO:0006979 123 0.067
protein desumoylation GO:0016926 2 0.066
response to oxygen levels GO:0070482 62 0.064
mitotic cell cycle GO:0000278 195 0.064
protein modification by small protein conjugation or removal GO:0070647 207 0.064
cellular amino acid metabolic process GO:0006520 103 0.063
protein complex disassembly GO:0043241 40 0.061
dna metabolic process GO:0006259 303 0.060
regulation of intracellular transport GO:0032386 159 0.057
cellular ketone metabolic process GO:0042180 84 0.055
organic cyclic compound catabolic process GO:1901361 295 0.054
regulation of cellular ketone metabolic process GO:0010565 66 0.051
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
translational initiation GO:0006413 24 0.047
organophosphate catabolic process GO:0046434 232 0.044
t cell activation GO:0042110 289 0.044
negative regulation of molecular function GO:0044092 258 0.043
regulation of proteolysis GO:0030162 164 0.043
Human Mouse
cellular macromolecule catabolic process GO:0044265 206 0.042
Human
posttranscriptional regulation of gene expression GO:0010608 155 0.041
ubiquitin dependent protein catabolic process GO:0006511 129 0.041
protein catabolic process GO:0030163 221 0.041
Human
peptidyl amino acid modification GO:0018193 336 0.041
transmembrane transport GO:0055085 412 0.040
spermatogenesis GO:0007283 284 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.040
regulation of protein catabolic process GO:0042176 108 0.039
Human
nuclear transport GO:0051169 139 0.038
protein modification by small protein conjugation GO:0032446 187 0.038
regulation of protein localization GO:0032880 231 0.038
protein methylation GO:0006479 81 0.037
intracellular protein transport GO:0006886 204 0.037
regulation of translation GO:0006417 71 0.036
protein alkylation GO:0008213 81 0.036
cellular protein catabolic process GO:0044257 155 0.035
Human
nucleocytoplasmic transport GO:0006913 139 0.035
organonitrogen compound biosynthetic process GO:1901566 192 0.035
cytokine production GO:0001816 319 0.034
heterocycle catabolic process GO:0046700 280 0.033
cristae formation GO:0042407 3 0.032
regulation of cell cycle GO:0051726 281 0.032
male gamete generation GO:0048232 285 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
nitrogen compound transport GO:0071705 271 0.032
macromolecule methylation GO:0043414 120 0.031
ras protein signal transduction GO:0007265 77 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
Human
regulation of cytoplasmic transport GO:1903649 112 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
regulation of proteasomal protein catabolic process GO:0061136 46 0.030
Human
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of protein transport GO:0051223 163 0.029
aromatic compound catabolic process GO:0019439 286 0.028
leukocyte proliferation GO:0070661 172 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
regulation of cellular protein catabolic process GO:1903362 61 0.028
Human
signal transduction by p53 class mediator GO:0072331 51 0.027
gland development GO:0048732 330 0.027
cellular biogenic amine metabolic process GO:0006576 28 0.027
regulation of endopeptidase activity GO:0052548 89 0.027
Human Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
positive regulation of protein transport GO:0051222 93 0.026
methylation GO:0032259 134 0.026
leukocyte differentiation GO:0002521 342 0.026
skeletal system development GO:0001501 356 0.026
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.026
cellular protein complex assembly GO:0043623 116 0.025
regulation of cytokine production GO:0001817 266 0.025
response to organic cyclic compound GO:0014070 198 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
mitochondrial membrane organization GO:0007006 26 0.025
cell cycle arrest GO:0007050 37 0.025
g1 s transition of mitotic cell cycle GO:0000082 57 0.025
regulation of intracellular protein transport GO:0033157 82 0.025
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.024
connective tissue development GO:0061448 179 0.024
cellularization GO:0007349 1 0.023
cation transport GO:0006812 399 0.023
protein ubiquitination GO:0016567 171 0.023
response to reactive oxygen species GO:0000302 56 0.023
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.023
response to inorganic substance GO:0010035 96 0.023
organic hydroxy compound biosynthetic process GO:1901617 77 0.022
response to acid chemical GO:0001101 111 0.022
nuclear export GO:0051168 34 0.022
membrane organization GO:0061024 245 0.022
polyamine biosynthetic process GO:0006596 2 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
pole plasm assembly GO:0007315 2 0.021
apoptotic signaling pathway GO:0097190 306 0.021
Human
maternal determination of anterior posterior axis embryo GO:0008358 2 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
myeloid cell differentiation GO:0030099 233 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
protein modification by small protein removal GO:0070646 21 0.021
histone h4 k16 acetylation GO:0043984 3 0.021
transcription from rna polymerase i promoter GO:0006360 13 0.021
positive regulation of organelle organization GO:0010638 128 0.020
tube formation GO:0035148 140 0.020
oocyte anterior posterior axis specification GO:0007314 2 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
stem cell development GO:0048864 219 0.020
inflammatory response GO:0006954 244 0.020
protein targeting GO:0006605 143 0.020
developmental maturation GO:0021700 193 0.020
organonitrogen compound catabolic process GO:1901565 264 0.019
photoreceptor cell morphogenesis GO:0008594 3 0.019
regulation of defense response GO:0031347 233 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
microtubule based process GO:0007017 236 0.019
regulation of organelle organization GO:0033043 289 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
epithelial cell development GO:0002064 159 0.019
response to organonitrogen compound GO:0010243 246 0.019
protein maturation GO:0051604 176 0.019
cellular response to dna damage stimulus GO:0006974 207 0.019
cell type specific apoptotic process GO:0097285 268 0.018
regulation of secretion by cell GO:1903530 249 0.018
chromosome organization involved in meiosis GO:0070192 39 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
Human Mouse
lymphocyte proliferation GO:0046651 164 0.018
response to hypoxia GO:0001666 58 0.018
female gamete generation GO:0007292 74 0.018
nucleotide excision repair GO:0006289 13 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
regulation of secretion GO:0051046 274 0.017
positive regulation of endopeptidase activity GO:0010950 43 0.017
Human Mouse
cell maturation GO:0048469 127 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.017
nls bearing protein import into nucleus GO:0006607 2 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
regulation of transferase activity GO:0051338 263 0.017
skin development GO:0043588 220 0.017
dna recombination GO:0006310 92 0.017
glycosyl compound catabolic process GO:1901658 206 0.016
hexose metabolic process GO:0019318 98 0.016
Rat
positive regulation of cellular catabolic process GO:0031331 148 0.016
regulation of cell activation GO:0050865 289 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
response to decreased oxygen levels GO:0036293 59 0.016
regulation of inflammatory response GO:0050727 147 0.016
stem cell differentiation GO:0048863 268 0.016
innate immune response GO:0045087 157 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
placenta development GO:0001890 140 0.015
cellular response to lipid GO:0071396 145 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
regulation of ion transport GO:0043269 215 0.015
epidermis development GO:0008544 187 0.015
nuclear import GO:0051170 95 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
response to light stimulus GO:0009416 135 0.015
positive regulation of cell death GO:0010942 224 0.015
second messenger mediated signaling GO:0019932 73 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
multicellular organismal signaling GO:0035637 91 0.015
fat cell differentiation GO:0045444 160 0.015
phosphatidylethanolamine metabolic process GO:0046337 2 0.015
response to radiation GO:0009314 165 0.015
cation homeostasis GO:0055080 212 0.015
nuclear division GO:0000280 158 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
male sex differentiation GO:0046661 109 0.014
positive regulation of intracellular transport GO:0032388 70 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
cellular amide metabolic process GO:0043603 58 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
defense response to bacterium GO:0042742 119 0.014
nucleotide metabolic process GO:0009117 332 0.014
homeostasis of number of cells GO:0048872 210 0.014
protein localization to nucleus GO:0034504 121 0.014
ion transmembrane transport GO:0034220 361 0.014
rhythmic process GO:0048511 174 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
oocyte construction GO:0007308 2 0.014
purine nucleoside catabolic process GO:0006152 205 0.013
cofactor metabolic process GO:0051186 80 0.013
protein processing GO:0016485 163 0.013
response to lipopolysaccharide GO:0032496 128 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
t cell differentiation GO:0030217 174 0.013
pyridine containing compound catabolic process GO:0072526 4 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
transmission of nerve impulse GO:0019226 76 0.013
neuron apoptotic process GO:0051402 142 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
multicellular organism growth GO:0035264 161 0.013
oxidation reduction process GO:0055114 342 0.013
oogenesis GO:0048477 56 0.013
negative regulation of protein modification process GO:0031400 163 0.013
cellular response to acid chemical GO:0071229 68 0.013
regulation of transmembrane transport GO:0034762 128 0.013
cellular homeostasis GO:0019725 240 0.013
negative regulation of lipid metabolic process GO:0045833 30 0.013
sensory organ morphogenesis GO:0090596 242 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
Rat
regulation of cell cycle process GO:0010564 160 0.013
protein localization to membrane GO:0072657 108 0.013
segmentation GO:0035282 93 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.013
Human
development of primary male sexual characteristics GO:0046546 88 0.013
macromolecule catabolic process GO:0009057 281 0.013
Human
ossification GO:0001503 216 0.013
cellular response to oxidative stress GO:0034599 76 0.012
regulation of protein complex assembly GO:0043254 83 0.012
spermatid differentiation GO:0048515 115 0.012
sensory perception GO:0007600 245 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
single organism nuclear import GO:1902593 95 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
nucleoside catabolic process GO:0009164 206 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
sequestering of calcium ion GO:0051208 18 0.012
peptide hormone secretion GO:0030072 109 0.012
regulation of tube size GO:0035150 57 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
male gonad development GO:0008584 88 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
regulation of ran protein signal transduction GO:0032015 3 0.012
regulation of t cell activation GO:0050863 170 0.012
regulation of hydrolase activity GO:0051336 246 0.012
Human Mouse
protein localization to organelle GO:0033365 185 0.012
alcohol metabolic process GO:0006066 116 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
negative regulation of immune system process GO:0002683 209 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
striated muscle tissue development GO:0014706 293 0.011
b cell activation GO:0042113 161 0.011
mitotic cell cycle process GO:1903047 159 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
mitochondrial transport GO:0006839 36 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
protein import GO:0017038 101 0.011
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
skeletal system morphogenesis GO:0048705 203 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
oocyte axis specification GO:0007309 2 0.011
female sex differentiation GO:0046660 84 0.011
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
photoreceptor cell development GO:0042461 40 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
exocytosis GO:0006887 121 0.011
positive regulation of proteolysis GO:0045862 85 0.011
Human Mouse
skeletal muscle organ development GO:0060538 163 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
glucose homeostasis GO:0042593 128 0.011
Rat
action potential GO:0001508 78 0.011
positive regulation of cell motility GO:2000147 116 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of cell migration GO:0030334 219 0.011
neural tube development GO:0021915 160 0.011
regulation of homeostatic process GO:0032844 182 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
muscle cell development GO:0055001 133 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
maintenance of location GO:0051235 89 0.011
actin cytoskeleton organization GO:0030036 220 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
rna processing GO:0006396 105 0.011
regulation of mrna metabolic process GO:1903311 43 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
Human
amide transport GO:0042886 138 0.010
positive regulation of gtp catabolic process GO:0033126 85 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
regulation of kinase activity GO:0043549 249 0.010
muscle tissue development GO:0060537 308 0.010
lens development in camera type eye GO:0002088 62 0.010
purine containing compound catabolic process GO:0072523 213 0.010
regulation of neuron death GO:1901214 134 0.010
positive regulation of immune effector process GO:0002699 107 0.010
purine nucleotide metabolic process GO:0006163 302 0.010
response to epidermal growth factor GO:0070849 4 0.010
cellular response to oxygen levels GO:0071453 20 0.010
regulation of membrane potential GO:0042391 192 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
Human

Psme3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
disease of cellular proliferation DOID:14566 0 0.012
large intestine cancer DOID:5672 0 0.012
cancer DOID:162 0 0.012
intestinal cancer DOID:10155 0 0.012
colon cancer DOID:219 0 0.012
organ system cancer DOID:0050686 0 0.012
colorectal cancer DOID:9256 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012
neurodegenerative disease DOID:1289 0 0.010
central nervous system disease DOID:331 0 0.010