|
|
epidermis development
|
GO:0008544 |
187 |
0.917
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.839
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.736
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.728
|
Zebrafish |
|
|
urogenital system development
|
GO:0001655 |
261 |
0.680
|
Mouse |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.646
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.613
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.584
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.584
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.558
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.555
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.546
|
Zebrafish Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.540
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.516
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.506
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.503
|
Zebrafish Mouse |
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.478
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.475
|
Mouse |
|
|
kidney development
|
GO:0001822 |
213 |
0.469
|
Mouse |
|
|
limb development
|
GO:0060173 |
166 |
0.462
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.425
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.423
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.420
|
Mouse Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.416
|
|
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.416
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.409
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.408
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.397
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.394
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.392
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.385
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.384
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.381
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.370
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.366
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.362
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.355
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.349
|
Mouse |
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.341
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.336
|
Mouse Fly |
|
|
digestive system development
|
GO:0055123 |
200 |
0.332
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.329
|
Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.327
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.323
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.319
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.318
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.318
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.317
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.316
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.316
|
Fly |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.313
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.311
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.309
|
Mouse |
|
|
pallium development
|
GO:0021543 |
120 |
0.307
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.303
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.303
|
Mouse |
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.303
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.302
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.301
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.299
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.295
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.294
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.293
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.291
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.289
|
Fly |
|
|
appendage development
|
GO:0048736 |
166 |
0.283
|
Mouse Fly |
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
5 |
0.278
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.277
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.276
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.275
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
128 |
0.270
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.267
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.266
|
Mouse |
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.264
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.260
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.246
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.246
|
Mouse |
|
|
neural tube closure
|
GO:0001843 |
90 |
0.245
|
Mouse |
|
|
lung development
|
GO:0030324 |
164 |
0.243
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.241
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.241
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.239
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.237
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.237
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.234
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.234
|
Fly |
|
|
hair follicle development
|
GO:0001942 |
85 |
0.234
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.229
|
Mouse |
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.229
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.229
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.228
|
Mouse |
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.227
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.226
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.226
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.224
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.222
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.221
|
Mouse |
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.220
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.217
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.217
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.216
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
41 |
0.213
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.210
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.209
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.205
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.205
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.205
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.203
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.203
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.203
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.203
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.198
|
|
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.194
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.194
|
Mouse |
|
|
positive regulation of lymphocyte apoptotic process
|
GO:0070230 |
13 |
0.194
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.192
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.192
|
Fly |
|
|
nephron development
|
GO:0072006 |
109 |
0.192
|
Mouse |
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.192
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.190
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.190
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.189
|
Mouse |
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.188
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.186
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.183
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.181
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.181
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.180
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.180
|
Mouse |
|
|
somite development
|
GO:0061053 |
81 |
0.180
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.178
|
|
|
|
branching involved in ureteric bud morphogenesis
|
GO:0001658 |
56 |
0.178
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.175
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.174
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.173
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.171
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.169
|
Mouse |
|
|
embryonic digit morphogenesis
|
GO:0042733 |
56 |
0.169
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.168
|
Fly |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.168
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.167
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.166
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.164
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.163
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.162
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.161
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.160
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.160
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.159
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.159
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.158
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.157
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.157
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.156
|
Mouse Worm |
|
|
epidermis morphogenesis
|
GO:0048730 |
33 |
0.156
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.154
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.153
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.152
|
Zebrafish |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.151
|
Fly |
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.151
|
Mouse |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.150
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.150
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.149
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.149
|
|
|
|
endothelium development
|
GO:0003158 |
45 |
0.148
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.147
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.144
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.143
|
Mouse |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.142
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.142
|
Zebrafish Mouse Fly |
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.141
|
|
|
|
hypophysis morphogenesis
|
GO:0048850 |
3 |
0.140
|
|
|
|
trachea cartilage morphogenesis
|
GO:0060535 |
4 |
0.140
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.140
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.140
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.139
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.139
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.138
|
Fly |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.137
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.136
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.136
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.136
|
Fly |
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.135
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.135
|
Mouse Fly |
|
|
developmental programmed cell death
|
GO:0010623 |
41 |
0.134
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.133
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.133
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.133
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.133
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.130
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.130
|
Zebrafish Fly |
|
|
hemostasis
|
GO:0007599 |
78 |
0.129
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.129
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.128
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.128
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
49 |
0.128
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.127
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.127
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.127
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.127
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.126
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.126
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.126
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.125
|
Zebrafish Fly |
|
|
renal vesicle induction
|
GO:0072034 |
3 |
0.125
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.124
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.124
|
Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.123
|
Mouse Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.123
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.122
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.121
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.121
|
Fly |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.120
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
176 |
0.120
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.120
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.120
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.119
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.119
|
Fly |
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.118
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.117
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.116
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
4 |
0.116
|
|
|
|
neuron fate specification
|
GO:0048665 |
30 |
0.116
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.115
|
|
|
|
paramesonephric duct development
|
GO:0061205 |
3 |
0.115
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.115
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.114
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.114
|
Mouse |
|
|
bone development
|
GO:0060348 |
120 |
0.114
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.114
|
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
28 |
0.114
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.113
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.112
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.110
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.110
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.110
|
Fly |
|
|
blastocyst development
|
GO:0001824 |
80 |
0.109
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.109
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.109
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.109
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.108
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.108
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.108
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.108
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.107
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.105
|
Fly |
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.105
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.105
|
Fly |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.105
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.104
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
44 |
0.104
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.104
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.104
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.103
|
Mouse |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.102
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.102
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.102
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.102
|
|
|
|
mesonephric duct morphogenesis
|
GO:0072180 |
4 |
0.100
|
|
|
|
water homeostasis
|
GO:0030104 |
27 |
0.100
|
|
|
|
progesterone secretion
|
GO:0042701 |
1 |
0.100
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.099
|
Mouse |
|
|
sensory perception
|
GO:0007600 |
245 |
0.099
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.099
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.099
|
Mouse |
|
|
hair cell differentiation
|
GO:0035315 |
40 |
0.098
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.098
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.098
|
|
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
38 |
0.097
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.096
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.096
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.096
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.095
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.095
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.094
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.094
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.094
|
Mouse |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.094
|
|
|
|
inner medullary collecting duct development
|
GO:0072061 |
2 |
0.093
|
|
|
|
midbrain hindbrain boundary maturation
|
GO:0021732 |
1 |
0.092
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
27 |
0.091
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.091
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.091
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.091
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.090
|
|
|
|
cardiac right atrium morphogenesis
|
GO:0003213 |
3 |
0.090
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.090
|
Mouse |
|
|
endoderm formation
|
GO:0001706 |
20 |
0.088
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.087
|
Mouse |
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.087
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.086
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.086
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.086
|
Fly |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.086
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.086
|
|
|
|
tissue regeneration
|
GO:0042246 |
22 |
0.086
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.086
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.086
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.085
|
|
|
|
establishment of planar polarity involved in neural tube closure
|
GO:0090177 |
15 |
0.085
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.085
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.085
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.083
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.083
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.083
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.083
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
42 |
0.082
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.082
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.082
|
Fly |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.081
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.081
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.081
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.081
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.081
|
Mouse |
|
|
somatotropin secreting cell differentiation
|
GO:0060126 |
4 |
0.081
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.081
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
18 |
0.081
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.080
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.080
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.080
|
|
|
|
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation
|
GO:2000079 |
1 |
0.080
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
53 |
0.079
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.079
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.079
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.078
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.078
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.077
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.077
|
|
|
|
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
|
GO:0014834 |
3 |
0.077
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.076
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.076
|
|
|
|
epithelial cell differentiation involved in kidney development
|
GO:0035850 |
23 |
0.076
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.076
|
Fly |
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.076
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.076
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.075
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.075
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.075
|
Fly |
|
|
positive regulation of epithelial cell proliferation involved in lung morphogenesis
|
GO:0060501 |
3 |
0.074
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.073
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.073
|
|
|
|
lung induction
|
GO:0060492 |
3 |
0.072
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.072
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
30 |
0.072
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.071
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.071
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.071
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.071
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.071
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.071
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
32 |
0.071
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.070
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.070
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.070
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.070
|
|
|
|
planar cell polarity pathway involved in pericardium morphogenesis
|
GO:0061354 |
2 |
0.070
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.069
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.069
|
|
|
|
planar cell polarity pathway involved in neural tube closure
|
GO:0090179 |
14 |
0.069
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.069
|
|
|
|
midbrain hindbrain boundary maturation during brain development
|
GO:0022004 |
1 |
0.069
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.068
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.067
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.067
|
|
|
|
central nervous system vasculogenesis
|
GO:0022009 |
3 |
0.067
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.067
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.067
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.067
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.067
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.066
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.066
|
Mouse |
|
|
hair follicle morphogenesis
|
GO:0031069 |
29 |
0.066
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
37 |
0.065
|
|
|
|
satellite cell activation involved in skeletal muscle regeneration
|
GO:0014901 |
3 |
0.065
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.065
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.065
|
Fly |
|
|
germ cell development
|
GO:0007281 |
185 |
0.065
|
Fly |
|
|
midgut development
|
GO:0007494 |
4 |
0.064
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.064
|
|
|
|
regulation of keratinocyte differentiation
|
GO:0045616 |
11 |
0.064
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.064
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.064
|
|
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
33 |
0.063
|
Mouse |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.063
|
|
|
|
morphogenesis of an epithelial fold
|
GO:0060571 |
28 |
0.063
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.063
|
Mouse |
|
|
cerebellum development
|
GO:0021549 |
77 |
0.063
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.062
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.062
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.062
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.062
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.061
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
18 |
0.061
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.061
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.061
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.061
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.061
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
31 |
0.061
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.060
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.060
|
|
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
4 |
0.060
|
|
|
|
regulation of thymocyte apoptotic process
|
GO:0070243 |
14 |
0.060
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.060
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.059
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.059
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.059
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.059
|
|
|
|
maintenance of cell number
|
GO:0098727 |
3 |
0.058
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.058
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.058
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.058
|
Mouse |
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.058
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.058
|
|
|
|
cranial nerve development
|
GO:0021545 |
41 |
0.058
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
51 |
0.057
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.057
|
|
|
|
ventral midline development
|
GO:0007418 |
4 |
0.057
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.057
|
Mouse |
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.057
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.057
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
46 |
0.056
|
|
|
|
negative regulation of photoreceptor cell differentiation
|
GO:0046533 |
4 |
0.056
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.056
|
|
|
|
prevention of polyspermy
|
GO:0060468 |
4 |
0.056
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.055
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.055
|
|
|
|
wnt signaling pathway involved in forebrain neuroblast division
|
GO:0021874 |
2 |
0.055
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.055
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.055
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.054
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
53 |
0.054
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.054
|
|
|
|
retinal blood vessel morphogenesis
|
GO:0061304 |
3 |
0.054
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.054
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.054
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
19 |
0.054
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.053
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.053
|
|
|
|
mesonephric duct formation
|
GO:0072181 |
2 |
0.053
|
|
|
|
establishment of organ orientation
|
GO:0048561 |
1 |
0.053
|
|
|
|
regulation of neural retina development
|
GO:0061074 |
3 |
0.053
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.052
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.052
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.052
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
33 |
0.052
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.052
|
|
|
|
negative regulation of catenin import into nucleus
|
GO:0035414 |
2 |
0.052
|
|
|
|
developmental induction
|
GO:0031128 |
34 |
0.052
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.052
|
Zebrafish |
|
|
diencephalon development
|
GO:0021536 |
63 |
0.052
|
|
|
|
regulation of asymmetric cell division
|
GO:0009786 |
4 |
0.051
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
28 |
0.051
|
|
|
|
regulation of anagen
|
GO:0051884 |
1 |
0.051
|
|
|
|
positive regulation of mesonephros development
|
GO:0061213 |
20 |
0.051
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.051
|
|
|
|
organ induction
|
GO:0001759 |
21 |
0.051
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.051
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.051
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.050
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.050
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.050
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.050
|
Zebrafish |
|
|
blood circulation
|
GO:0008015 |
195 |
0.049
|
|
|
|
stem cell division
|
GO:0017145 |
30 |
0.049
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.049
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.049
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.049
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.048
|
|
|
|
schwann cell differentiation
|
GO:0014037 |
26 |
0.048
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.048
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.048
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
27 |
0.048
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.048
|
Mouse |
|
|
renal inner medulla development
|
GO:0072053 |
3 |
0.048
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.048
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.048
|
Worm |
|
|
cell proliferation involved in metanephros development
|
GO:0072203 |
9 |
0.048
|
Mouse |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.048
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.048
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.048
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.048
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.048
|
|
|
|
pituitary gland development
|
GO:0021983 |
38 |
0.048
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.047
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.047
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.047
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.047
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.047
|
|
|
|
establishment of planar polarity involved in nephron morphogenesis
|
GO:0072046 |
1 |
0.046
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.046
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.046
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.046
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
53 |
0.046
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.045
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.045
|
|
