Mus musculus

121 known processes

Ptf1a

pancreas specific transcription factor, 1a

(Aliases: bHLHa29,PTF1-p48,PTF1p48)

Ptf1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
auditory receptor cell fate determination GO:0042668 3 0.998
Mouse
axonogenesis GO:0007409 274 0.995
Mouse
pancreatic a cell fate commitment GO:0003326 2 0.993
Mouse
neuron migration GO:0001764 122 0.993
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.993
Mouse
spinal cord development GO:0021510 81 0.989
Mouse
cardiac right ventricle formation GO:0003219 3 0.989
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.986
Mouse
pancreatic pp cell differentiation GO:0003312 2 0.984
Mouse
regulation of neuron projection development GO:0010975 169 0.983
Mouse
regulation of mast cell differentiation GO:0060375 3 0.979
Mouse
auditory receptor cell fate specification GO:0042667 1 0.978
Mouse
embryonic heart tube formation GO:0003144 1 0.978
Mouse
regulation of auditory receptor cell differentiation GO:0045607 4 0.977
Mouse
amacrine cell differentiation GO:0035881 5 0.972
axon guidance GO:0007411 141 0.971
Mouse
cell fate commitment GO:0045165 210 0.971
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.967
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.961
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.960
Mouse
cell differentiation in spinal cord GO:0021515 53 0.958
Mouse
lymphocyte differentiation GO:0030098 242 0.958
Mouse
embryonic skeletal system development GO:0048706 120 0.957
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.953
Mouse
pancreas development GO:0031016 57 0.948
pancreatic pp cell fate commitment GO:0003329 2 0.948
Mouse
regionalization GO:0003002 337 0.947
Mouse
retina morphogenesis in camera type eye GO:0060042 45 0.947
regulation of neuron differentiation GO:0045664 281 0.946
Mouse
appendage morphogenesis GO:0035107 149 0.943
Mouse
forebrain development GO:0030900 302 0.922
Mouse
dendrite development GO:0016358 115 0.922
Mouse
endocrine system development GO:0035270 98 0.919
Mouse
glial cell fate commitment GO:0021781 14 0.917
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.916
Mouse
neuron projection guidance GO:0097485 141 0.902
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.899
Mouse
heart valve morphogenesis GO:0003179 21 0.899
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.896
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.896
Mouse
connective tissue development GO:0061448 179 0.894
Mouse
appendage development GO:0048736 166 0.883
Mouse
epithelial cell fate commitment GO:0072148 13 0.883
Mouse
cerebral cortex development GO:0021987 86 0.873
Mouse
chemotaxis GO:0006935 247 0.870
Mouse
cell fate determination GO:0001709 32 0.868
Mouse
positive regulation of cell development GO:0010720 237 0.867
Mouse
erythrocyte differentiation GO:0030218 88 0.867
Mouse
megakaryocyte differentiation GO:0030219 26 0.866
Mouse
myeloid cell differentiation GO:0030099 233 0.862
Mouse
central nervous system neuron differentiation GO:0021953 162 0.862
Mouse
hemangioblast cell differentiation GO:0060217 1 0.859
Mouse
cell fate specification GO:0001708 72 0.857
Mouse
diencephalon development GO:0021536 63 0.851
Mouse
aortic valve morphogenesis GO:0003180 4 0.850
Mouse
hindbrain development GO:0030902 128 0.845
hindlimb morphogenesis GO:0035137 42 0.844
Mouse
astrocyte fate commitment GO:0060018 4 0.839
Mouse
epithelial tube morphogenesis GO:0060562 303 0.836
Mouse
heart formation GO:0060914 16 0.833
Mouse
positive regulation of nervous system development GO:0051962 221 0.830
Mouse
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.826
Mouse
pancreatic a cell differentiation GO:0003310 7 0.826
Mouse
embryonic limb morphogenesis GO:0030326 126 0.822
Mouse
regulation of osteoblast differentiation GO:0045667 67 0.818
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.817
Mouse
leukocyte differentiation GO:0002521 342 0.816
Mouse
cardiac epithelial to mesenchymal transition GO:0060317 18 0.811
Mouse
epidermis development GO:0008544 187 0.811
Mouse
mitochondrion distribution GO:0048311 4 0.808
Mouse
neuron fate specification GO:0048665 30 0.807
Mouse
regulation of stem cell differentiation GO:2000736 50 0.802
Mouse
mesenchymal cell development GO:0014031 93 0.800
Mouse
bmp signaling pathway GO:0030509 93 0.800
Mouse
skin development GO:0043588 220 0.796
Mouse
skeletal system morphogenesis GO:0048705 203 0.792
Mouse
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.792
Mouse
camera type eye development GO:0043010 266 0.790
response to growth factor GO:0070848 198 0.788
Mouse
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.786
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.783
regulation of cell projection organization GO:0031344 206 0.781
Mouse
regulation of muscle cell apoptotic process GO:0010660 17 0.778
Mouse
inner ear receptor cell fate commitment GO:0060120 6 0.775
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.766
Mouse
semaphorin plexin signaling pathway GO:0071526 21 0.762
Mouse
cerebellar cortex development GO:0021695 48 0.761
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.759
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.759
Mouse
neural retina development GO:0003407 41 0.758
cell proliferation involved in heart valve development GO:2000793 2 0.755
Mouse
negative regulation of cell proliferation GO:0008285 296 0.749
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.743
Mouse
mitral valve morphogenesis GO:0003183 4 0.740
Mouse
regulation of chromatin modification GO:1903308 57 0.738
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.737
Mouse
tendon cell differentiation GO:0035990 4 0.736
Mouse
negative regulation of nervous system development GO:0051961 156 0.735
Mouse
regulation of cell motility GO:2000145 236 0.732
Mouse
auditory receptor cell differentiation GO:0042491 37 0.729
Mouse
visceral serous pericardium development GO:0061032 2 0.725
Mouse
regulation of circadian rhythm GO:0042752 58 0.713
Mouse
sensory organ morphogenesis GO:0090596 242 0.712
smoothened signaling pathway GO:0007224 105 0.709
cardioblast proliferation GO:0003263 8 0.708
Mouse
myeloid leukocyte activation GO:0002274 83 0.697
transdifferentiation GO:0060290 1 0.695
Mouse
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.689
Mouse
motor neuron migration GO:0097475 4 0.685
negative regulation of ossification GO:0030279 49 0.681
Mouse
skeletal system development GO:0001501 356 0.679
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.676
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.675
limb morphogenesis GO:0035108 149 0.670
Mouse
b cell activation GO:0042113 161 0.670
Mouse
regulation of epidermis development GO:0045682 33 0.664
Mouse
neuron projection extension GO:1990138 64 0.662
odontogenesis GO:0042476 78 0.657
Mouse
neural tube development GO:0021915 160 0.652
Mouse
deltoid tuberosity development GO:0035993 3 0.649
Mouse
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.646
Mouse
stem cell proliferation GO:0072089 117 0.645
Mouse
tendon formation GO:0035992 4 0.641
Mouse
peripheral nervous system development GO:0007422 53 0.641
Mouse
neuroblast differentiation GO:0014016 2 0.638
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.632
Mouse
central nervous system neuron development GO:0021954 67 0.630
Mouse
stem cell development GO:0048864 219 0.623
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.620
Mouse
ossification GO:0001503 216 0.619
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.618
digestive tract development GO:0048565 190 0.615
Mouse
skeletal muscle cell differentiation GO:0035914 66 0.615
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.614
endocardial cushion to mesenchymal transition GO:0090500 5 0.605
Mouse
cartilage development GO:0051216 140 0.602
Mouse
negative regulation of cell development GO:0010721 169 0.599
tube closure GO:0060606 91 0.585
Mouse
embryonic epithelial tube formation GO:0001838 130 0.584
Mouse
heart valve development GO:0003170 23 0.583
Mouse
mechanoreceptor differentiation GO:0042490 67 0.582
Mouse
respiratory system development GO:0060541 190 0.580
positive regulation of myeloid cell differentiation GO:0045639 43 0.579
Mouse
negative regulation of osteoblast differentiation GO:0045668 30 0.576
Mouse
somitogenesis GO:0001756 69 0.574
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.574
Mouse
intracellular distribution of mitochondria GO:0048312 1 0.574
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.573
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.572
Mouse
histone acetylation GO:0016573 41 0.566
Mouse
positive regulation of homeostatic process GO:0032846 64 0.563
Mouse
amine metabolic process GO:0009308 45 0.557
regulation of organ morphogenesis GO:2000027 144 0.556
Mouse
post embryonic retina morphogenesis in camera type eye GO:0060060 3 0.556
negative regulation of molecular function GO:0044092 258 0.555
Mouse
inner ear receptor cell differentiation GO:0060113 61 0.551
Mouse
mitral valve development GO:0003174 4 0.549
Mouse
determination of left right symmetry GO:0007368 80 0.546
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.544
Mouse
neuroblast fate determination GO:0007400 1 0.544
hair cell differentiation GO:0035315 40 0.539
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 14 0.533
peptidyl lysine modification GO:0018205 77 0.531
Mouse
regulation of transcription involved in cell fate commitment GO:0060850 15 0.529
cell fate determination involved in pattern specification GO:0060582 1 0.526
negative regulation of synapse maturation GO:2000297 2 0.523
Mouse
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.522
Mouse
gliogenesis GO:0042063 141 0.518
Mouse
collagen biosynthetic process GO:0032964 7 0.516
Mouse
head morphogenesis GO:0060323 34 0.509
Mouse
neural crest cell differentiation GO:0014033 54 0.509
Mouse
glandular epithelial cell differentiation GO:0002067 38 0.507
Mouse
cytokine production GO:0001816 319 0.506
Mouse
inflammatory response GO:0006954 244 0.506
regulation of muscle tissue development GO:1901861 97 0.506
Mouse
cell recognition GO:0008037 83 0.505
limb development GO:0060173 166 0.495
Mouse
clara cell differentiation GO:0060486 4 0.492
cell migration involved in endocardial cushion formation GO:0003273 3 0.491
chondrocyte differentiation GO:0002062 72 0.482
Mouse
mesenchyme development GO:0060485 152 0.478
Mouse
intestinal epithelial structure maintenance GO:0060729 4 0.477
Mouse
regulation of retina development in camera type eye GO:1902866 3 0.476
cellular amine metabolic process GO:0044106 44 0.474
muscle cell apoptotic process GO:0010657 18 0.473
Mouse
positive regulation of cell cycle GO:0045787 92 0.470
Mouse
epithelial cell proliferation GO:0050673 174 0.470
Mouse
positive regulation of cell motility GO:2000147 116 0.466
Mouse
cell fate commitment involved in pattern specification GO:0060581 14 0.464
autonomic nervous system development GO:0048483 43 0.464
Mouse
regulation of cartilage development GO:0061035 44 0.462
Mouse
tube formation GO:0035148 140 0.457
Mouse
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.457
Mouse
spinal cord motor neuron cell fate specification GO:0021520 13 0.454
sensory organ boundary specification GO:0008052 1 0.453
trophoblast giant cell differentiation GO:0060707 15 0.451
Mouse
monosaccharide metabolic process GO:0005996 106 0.450
primary neural tube formation GO:0014020 95 0.449
Mouse
positive regulation of synaptic plasticity GO:0031915 4 0.449
Mouse
astrocyte differentiation GO:0048708 43 0.449
Mouse
regulation of binding GO:0051098 111 0.448
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.446
Mouse
mesenchymal cell differentiation GO:0048762 107 0.444
Mouse
catecholamine biosynthetic process GO:0042423 11 0.443
Mouse
regulation of epidermal cell differentiation GO:0045604 21 0.443
Mouse
mesoderm morphogenesis GO:0048332 64 0.440
Mouse
negative regulation of immune system process GO:0002683 209 0.432
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.431
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.429
Mouse
catecholamine metabolic process GO:0006584 30 0.423
Mouse
protein ubiquitination GO:0016567 171 0.423
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.421
cell type specific apoptotic process GO:0097285 268 0.420
Mouse
regulation of keratinocyte proliferation GO:0010837 15 0.420
Mouse
peripheral nervous system neuron axonogenesis GO:0048936 3 0.419
regulation of jak stat cascade GO:0046425 34 0.413
Mouse
cardiac chamber formation GO:0003207 10 0.412
Mouse
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.408
digestive system development GO:0055123 200 0.406
Zebrafish Mouse Rat
regulation of stem cell proliferation GO:0072091 78 0.402
stem cell fate determination GO:0048867 2 0.398
definitive hemopoiesis GO:0060216 20 0.395
Mouse
homeostasis of number of cells GO:0048872 210 0.393
Mouse
eating behavior GO:0042755 15 0.393
Mouse
b cell differentiation GO:0030183 78 0.390
Mouse
retina development in camera type eye GO:0060041 119 0.389
cell migration involved in heart development GO:0060973 8 0.388
Mouse
keratinocyte proliferation GO:0043616 21 0.387
Mouse
regulation of cell cycle process GO:0010564 160 0.387
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.382
Mouse
cell cycle arrest GO:0007050 37 0.381
Mouse
eye photoreceptor cell development GO:0042462 31 0.379
regulation of axon guidance GO:1902667 13 0.378
histone modification GO:0016570 159 0.373
Mouse
ventral spinal cord interneuron differentiation GO:0021514 16 0.372
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.370
Mouse
neural crest cell migration GO:0001755 32 0.367
Mouse
regulation of histone modification GO:0031056 56 0.362
Mouse
spinal cord association neuron differentiation GO:0021527 14 0.361
Mouse
negative regulation of binding GO:0051100 39 0.359
Mouse
exocrine pancreas development GO:0031017 7 0.357
Zebrafish Rat
spinal cord motor neuron differentiation GO:0021522 35 0.356
regulation of tumor necrosis factor production GO:0032680 49 0.356
Mouse
extracellular structure organization GO:0043062 148 0.354
Mouse
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.353
peripheral nervous system neuron development GO:0048935 9 0.353
Mouse
glial cell differentiation GO:0010001 131 0.352
Mouse
pericardium development GO:0060039 16 0.352
Mouse
positive regulation of mitotic cell cycle GO:0045931 41 0.352
Mouse
developmental programmed cell death GO:0010623 41 0.351
Mouse
dentate gyrus development GO:0021542 14 0.350
Mouse
embryonic digit morphogenesis GO:0042733 56 0.347
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.342
ameboidal type cell migration GO:0001667 128 0.342
Mouse
gastrulation GO:0007369 116 0.340
Mouse
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.338
Mouse
calcium mediated signaling GO:0019722 46 0.337
Mouse
circadian rhythm GO:0007623 114 0.335
Mouse
hindbrain morphogenesis GO:0021575 46 0.329
peripheral nervous system neuron differentiation GO:0048934 9 0.329
Mouse
tongue development GO:0043586 18 0.327
Mouse
digestion GO:0007586 40 0.325
Mouse
regulation of cardioblast proliferation GO:0003264 9 0.324
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.323
Mouse
t cell differentiation GO:0030217 174 0.322
neuroblast proliferation GO:0007405 49 0.320
Mouse
chromatin organization GO:0006325 206 0.320
Mouse
formation of organ boundary GO:0010160 1 0.314
regulation of lymphocyte activation GO:0051249 240 0.314
regulation of system process GO:0044057 200 0.311
Mouse
ventral spinal cord development GO:0021517 48 0.311
hematopoietic stem cell differentiation GO:0060218 8 0.309
Mouse
neuron recognition GO:0008038 25 0.309
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.308
notch signaling pathway GO:0007219 71 0.306
Mouse
protein acylation GO:0043543 64 0.305
Mouse
positive regulation of apoptotic process GO:0043065 217 0.303
Mouse
endocardial cushion morphogenesis GO:0003203 18 0.301
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.300
hippocampus development GO:0021766 52 0.300
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.299
muscle tissue development GO:0060537 308 0.298
Mouse
cerebellar granule cell precursor proliferation GO:0021930 10 0.298
erythrocyte maturation GO:0043249 6 0.298
Mouse
neural precursor cell proliferation GO:0061351 121 0.297
Mouse
forebrain neuron development GO:0021884 30 0.295
negative regulation of cytokine production GO:0001818 84 0.294
Mouse
regulation of semaphorin plexin signaling pathway GO:2001260 1 0.294
Mouse
cardiac ventricle development GO:0003231 83 0.293
Mouse
neural tube closure GO:0001843 90 0.293
Mouse
pituitary gland development GO:0021983 38 0.292
sensory perception GO:0007600 245 0.291
cardiac ventricle formation GO:0003211 8 0.291
Mouse
sclerotome development GO:0061056 4 0.290
Mouse
ventricular cardiac muscle tissue development GO:0003229 38 0.288
Mouse
neuroblast fate commitment GO:0014017 1 0.287
regulation of cardiac muscle cell proliferation GO:0060043 23 0.285
positive regulation of glial cell differentiation GO:0045687 21 0.283
embryonic organ morphogenesis GO:0048562 276 0.282
Mouse
hair cycle GO:0042633 90 0.277
positive regulation of epidermal cell differentiation GO:0045606 6 0.276
Mouse
regulation of heart morphogenesis GO:2000826 22 0.275
Mouse
leukocyte apoptotic process GO:0071887 71 0.273
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.272
Mouse
cardiac muscle tissue development GO:0048738 130 0.268
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.267
spinal cord motor neuron migration GO:0097476 4 0.267
glial cell fate specification GO:0021780 5 0.266
epithelial to mesenchymal transition GO:0001837 47 0.265
Mouse
lateral inhibition GO:0046331 1 0.263
negative regulation of intracellular signal transduction GO:1902532 167 0.263
Mouse
regulation of mechanoreceptor differentiation GO:0045631 5 0.262
Mouse
myeloid dendritic cell differentiation GO:0043011 16 0.262
calcium ion transport GO:0006816 159 0.261
Mouse
striated muscle tissue development GO:0014706 293 0.260
Mouse
exocrine system development GO:0035272 45 0.258
Zebrafish Rat
divalent inorganic cation transport GO:0072511 178 0.256
Mouse
regulation of ion transport GO:0043269 215 0.256
Mouse
response to bmp GO:0071772 14 0.254
Mouse
retinal cone cell development GO:0046549 8 0.253
positive regulation of exit from mitosis GO:0031536 1 0.250
Mouse
mesenchyme morphogenesis GO:0072132 32 0.249
Mouse
peptidyl amino acid modification GO:0018193 336 0.247
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.247
Mouse
cardiac neural crest cell development involved in heart development GO:0061308 7 0.246
Mouse
negative regulation of transporter activity GO:0032410 7 0.245
Mouse
defense response to other organism GO:0098542 197 0.244
regulation of apoptotic signaling pathway GO:2001233 197 0.244
positive regulation of erythrocyte differentiation GO:0045648 11 0.243
Mouse
cell proliferation in hindbrain GO:0021534 10 0.243
regulation of gliogenesis GO:0014013 50 0.240
embryonic heart tube morphogenesis GO:0003143 51 0.240
Mouse
central nervous system morphogenesis GO:0021551 2 0.239
detection of molecule of bacterial origin GO:0032490 2 0.237
metencephalon development GO:0022037 89 0.235
digestive tract morphogenesis GO:0048546 147 0.231
Mouse
cerebellum morphogenesis GO:0021587 42 0.230
olfactory lobe development GO:0021988 32 0.230
spinal cord patterning GO:0021511 25 0.230
morphogenesis of a branching epithelium GO:0061138 193 0.228
response to transforming growth factor beta GO:0071559 88 0.228
Mouse
forebrain neuron differentiation GO:0021879 52 0.227
cerebral cortex neuron differentiation GO:0021895 19 0.227
outflow tract morphogenesis GO:0003151 53 0.226
Mouse
proton transport GO:0015992 35 0.223
Mouse
cellular response to calcium ion GO:0071277 14 0.223
Mouse
regulation of axon extension GO:0030516 43 0.223
extracellular matrix organization GO:0030198 147 0.223
Mouse
atrioventricular valve morphogenesis GO:0003181 13 0.222
Mouse
cerebellar cortex formation GO:0021697 22 0.221
photoreceptor cell development GO:0042461 40 0.217
regulation of leukocyte apoptotic process GO:2000106 56 0.216
cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 6 0.214
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.214
circulatory system process GO:0003013 197 0.213
muscle tissue morphogenesis GO:0060415 53 0.212
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.212
Mouse
apoptotic process involved in development GO:1902742 28 0.212
Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.210
neural tube formation GO:0001841 108 0.209
Mouse
lymph node development GO:0048535 18 0.207
axonal fasciculation GO:0007413 15 0.206
regulation of type b pancreatic cell apoptotic process GO:2000674 5 0.205
Mouse
somite development GO:0061053 81 0.205
Mouse
mitotic cell cycle GO:0000278 195 0.205
Mouse
spleen development GO:0048536 39 0.204
regulation of peptidyl lysine acetylation GO:2000756 22 0.204
Mouse
enteroendocrine cell differentiation GO:0035883 16 0.204
Mouse
regulation of inner ear receptor cell differentiation GO:2000980 5 0.204
Mouse
cardiocyte differentiation GO:0035051 87 0.203
Mouse
mitotic cell cycle process GO:1903047 159 0.202
Mouse
mesoderm development GO:0007498 100 0.201
Mouse
telencephalon development GO:0021537 186 0.200
Mouse
collagen fibril organization GO:0030199 32 0.198
Mouse
face morphogenesis GO:0060325 29 0.197
Mouse
positive regulation of leukocyte apoptotic process GO:2000108 21 0.197
endochondral bone morphogenesis GO:0060350 50 0.196
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.195
keratinocyte differentiation GO:0030216 48 0.195
collagen metabolic process GO:0032963 17 0.194
Mouse
negative regulation of myeloid cell differentiation GO:0045638 38 0.194
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.194
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.192
Mouse
positive regulation of stem cell proliferation GO:2000648 59 0.191
regulation of glial cell differentiation GO:0045685 41 0.191
regulation of striated muscle cell apoptotic process GO:0010662 11 0.191
Mouse
neuromuscular process GO:0050905 99 0.189
Mouse
formation of primary germ layer GO:0001704 77 0.188
Mouse
motor neuron axon guidance GO:0008045 26 0.184
epithelial cell development GO:0002064 159 0.184
Mouse
regulation of exit from mitosis GO:0007096 1 0.183
Mouse
tumor necrosis factor production GO:0032640 50 0.183
Mouse
regulation of t cell activation GO:0050863 170 0.183
forebrain generation of neurons GO:0021872 63 0.182
atrioventricular node development GO:0003162 3 0.182
internal peptidyl lysine acetylation GO:0018393 42 0.181
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.180
regulation of extracellular matrix organization GO:1903053 11 0.179
Mouse
hexose metabolic process GO:0019318 98 0.179
sterol homeostasis GO:0055092 45 0.178
cerebellar purkinje cell differentiation GO:0021702 13 0.178
regulation of cardioblast differentiation GO:0051890 3 0.178
positive regulation of gastrulation GO:2000543 6 0.178
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.176
regulation of neural retina development GO:0061074 3 0.174
gland development GO:0048732 330 0.174
Mouse
jak stat cascade GO:0007259 42 0.173
Mouse
cellular ketone metabolic process GO:0042180 84 0.172
negative regulation of tumor necrosis factor production GO:0032720 17 0.172
Mouse
cell proliferation in forebrain GO:0021846 30 0.170
negative regulation of protein phosphorylation GO:0001933 126 0.169
negative regulation of protein modification process GO:0031400 163 0.168
Mouse
canonical wnt signaling pathway GO:0060070 130 0.168
determination of heart left right asymmetry GO:0061371 48 0.168
Mouse
positive regulation of cell cycle process GO:0090068 61 0.168
Mouse
negative regulation of muscle cell apoptotic process GO:0010656 9 0.167
Mouse
placenta development GO:0001890 140 0.166
Mouse
embryonic heart tube development GO:0035050 65 0.166
Mouse
mesenchymal to epithelial transition GO:0060231 12 0.165
Mouse
regulation of cardiac muscle cell apoptotic process GO:0010665 9 0.165
Mouse
protein processing GO:0016485 163 0.164
mesenchymal cell proliferation GO:0010463 44 0.164
Mouse
muscle cell differentiation GO:0042692 261 0.164
olfactory bulb development GO:0021772 30 0.163
multicellular organismal macromolecule metabolic process GO:0044259 19 0.163
Mouse
cellular response to external stimulus GO:0071496 88 0.162
Mouse
regulation of cell migration GO:0030334 219 0.162
regulation of transmembrane transport GO:0034762 128 0.161
Mouse
cardiac muscle cell apoptotic process GO:0010659 10 0.160
Mouse
stem cell division GO:0017145 30 0.160
negative regulation of chromosome organization GO:2001251 30 0.160
Mouse
morphogenesis of a branching structure GO:0001763 203 0.159
endocrine pancreas development GO:0031018 29 0.158
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.156
photoreceptor cell differentiation GO:0046530 52 0.155
cell proliferation in external granule layer GO:0021924 10 0.153
regulation of myeloid leukocyte differentiation GO:0002761 58 0.152
Mouse
hair follicle development GO:0001942 85 0.152
embryonic hindlimb morphogenesis GO:0035116 32 0.152
Mouse
regulation of erythrocyte differentiation GO:0045646 23 0.151
Mouse
axon extension involved in axon guidance GO:0048846 14 0.151
ovulation cycle GO:0042698 59 0.151
Mouse
oligodendrocyte differentiation GO:0048709 53 0.150
endocardial cushion development GO:0003197 26 0.150
Mouse
germ cell development GO:0007281 185 0.149
positive regulation of neuron projection development GO:0010976 79 0.148
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.148
Mouse
cerebellar purkinje cell layer development GO:0021680 26 0.148
negative regulation of glial cell differentiation GO:0045686 21 0.147
morphogenesis of a polarized epithelium GO:0001738 37 0.146
Mouse
mitochondrion localization GO:0051646 9 0.145
Mouse
peroxisome proliferator activated receptor signaling pathway GO:0035357 9 0.144
Mouse
internal protein amino acid acetylation GO:0006475 42 0.144
Mouse
forebrain regionalization GO:0021871 25 0.144
cardiac right atrium morphogenesis GO:0003213 3 0.144
regulation of neuroblast proliferation GO:1902692 27 0.144
rhythmic process GO:0048511 174 0.143
Mouse
inner ear morphogenesis GO:0042472 101 0.143
Mouse
establishment of epithelial cell polarity GO:0090162 10 0.142
Mouse
phagocytosis GO:0006909 66 0.142
apoptotic process involved in morphogenesis GO:0060561 25 0.141
Mouse
divalent metal ion transport GO:0070838 172 0.141
Mouse
lateral motor column neuron migration GO:0097477 3 0.140
developmental growth involved in morphogenesis GO:0060560 138 0.139
regulation of bmp signaling pathway GO:0030510 60 0.139
kidney epithelium development GO:0072073 121 0.139
regulation of organelle organization GO:0033043 289 0.139
Mouse
regulation of chromatin organization GO:1902275 57 0.139
Mouse
protein maturation GO:0051604 176 0.138
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.138
Mouse
feeding behavior GO:0007631 62 0.137
Mouse
cation transport GO:0006812 399 0.137
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.137
Mouse
coronary vasculature morphogenesis GO:0060977 9 0.137
Mouse
coronary vasculature development GO:0060976 12 0.136
Mouse
detection of stimulus involved in sensory perception GO:0050906 44 0.133
carbohydrate metabolic process GO:0005975 230 0.132
respiratory tube development GO:0030323 167 0.132
positive regulation of gliogenesis GO:0014015 27 0.131
positive regulation of apoptotic signaling pathway GO:2001235 95 0.130
primitive hemopoiesis GO:0060215 7 0.130
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.130
Mouse
regulation of chromosome organization GO:0033044 83 0.130
Mouse
pallium development GO:0021543 120 0.130
Mouse
cardiac chamber development GO:0003205 108 0.129
Mouse
cell maturation GO:0048469 127 0.128
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 35 0.127
regulation of collagen metabolic process GO:0010712 6 0.125
Mouse
cell adhesion GO:0007155 329 0.125
oligodendrocyte cell fate commitment GO:0021779 5 0.125
glomerular mesangial cell differentiation GO:0072008 3 0.124
multi multicellular organism process GO:0044706 109 0.124
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.124
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.123
stem cell differentiation GO:0048863 268 0.123
Mouse

Ptf1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.159
carbohydrate metabolism disease DOID:0050013 0 0.159
glucose metabolism disease DOID:4194 0 0.159
acquired metabolic disease DOID:0060158 0 0.159