Mus musculus

30 known processes

Ptges

prostaglandin E synthase

(Aliases: D2Ertd369e,2410099E23Rik,mPGES,mPGES-1,Pges)

Ptges biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.683
leukotriene production involved in inflammatory response GO:0002540 2 0.565
membrane lipid biosynthetic process GO:0046467 32 0.404
sphingolipid biosynthetic process GO:0030148 26 0.376
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.363
regulation of response to wounding GO:1903034 189 0.331
adaptive immune response GO:0002250 155 0.287
fatty acid derivative biosynthetic process GO:1901570 15 0.276
Human
ion transmembrane transport GO:0034220 361 0.263
negative regulation of immune system process GO:0002683 209 0.249
apoptotic signaling pathway GO:0097190 306 0.231
lipid biosynthetic process GO:0008610 179 0.229
Human
sensory perception of pain GO:0019233 47 0.190
icosanoid biosynthetic process GO:0046456 15 0.189
Human
ceramide biosynthetic process GO:0046513 20 0.185
carboxylic acid biosynthetic process GO:0046394 86 0.184
Human
regulation of cell activation GO:0050865 289 0.171
organic acid biosynthetic process GO:0016053 86 0.160
Human
organic acid transport GO:0015849 101 0.157
cellular amino acid metabolic process GO:0006520 103 0.156
response to endoplasmic reticulum stress GO:0034976 53 0.154
carboxylic acid transport GO:0046942 100 0.152
regulation of body fluid levels GO:0050878 162 0.146
inflammatory response GO:0006954 244 0.146
regulation of cell motility GO:2000145 236 0.141
monocarboxylic acid metabolic process GO:0032787 191 0.137
coagulation GO:0050817 78 0.134
ossification GO:0001503 216 0.129
engulfment of apoptotic cell GO:0043652 3 0.129
extracellular structure organization GO:0043062 148 0.127
regulation of cell adhesion GO:0030155 154 0.126
lipoxin a4 biosynthetic process GO:2001303 1 0.125
monocarboxylic acid biosynthetic process GO:0072330 61 0.124
Human
actin cytoskeleton organization GO:0030036 220 0.121
single organism cell adhesion GO:0098602 156 0.119
positive regulation of secretion by cell GO:1903532 114 0.112
lipid transport GO:0006869 98 0.111
cytokine production GO:0001816 319 0.111
glycerolipid metabolic process GO:0046486 122 0.110
membrane organization GO:0061024 245 0.110
regulation of secretion GO:0051046 274 0.108
skeletal system morphogenesis GO:0048705 203 0.107
organic anion transport GO:0015711 137 0.107
fatty acid biosynthetic process GO:0006633 41 0.103
Human
wound healing GO:0042060 157 0.103
regulation of engulfment of apoptotic cell GO:1901074 2 0.103
synaptic transmission GO:0007268 329 0.103
blood coagulation GO:0007596 76 0.101
anion transport GO:0006820 177 0.099
negative regulation of growth GO:0045926 99 0.098
unsaturated fatty acid biosynthetic process GO:0006636 15 0.098
Human
positive regulation of vasoconstriction GO:0045907 4 0.097
phosphatidylethanolamine metabolic process GO:0046337 2 0.097
extrinsic apoptotic signaling pathway GO:0097191 126 0.093
regulation of organelle organization GO:0033043 289 0.090
positive regulation of eosinophil migration GO:2000418 2 0.090
regulation of cellular amine metabolic process GO:0033238 20 0.089
regulation of multi organism process GO:0043900 111 0.089
icosanoid metabolic process GO:0006690 33 0.088
cell adhesion GO:0007155 329 0.088
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.088
female sex differentiation GO:0046660 84 0.087
ceramide metabolic process GO:0006672 31 0.087
lymphocyte differentiation GO:0030098 242 0.086
t cell activation GO:0042110 289 0.086
regulation of anatomical structure size GO:0090066 178 0.086
fatty acid derivative metabolic process GO:1901568 33 0.085
positive regulation of cellular amine metabolic process GO:0033240 5 0.085
urogenital system development GO:0001655 261 0.084
production of molecular mediator involved in inflammatory response GO:0002532 21 0.083
response to hyperoxia GO:0055093 2 0.083
cellular amine metabolic process GO:0044106 44 0.082
regulation of t cell activation GO:0050863 170 0.082
regulation of protein serine threonine kinase activity GO:0071900 157 0.081
cellular lipid metabolic process GO:0044255 323 0.081
alpha beta t cell activation GO:0046631 91 0.080
cellular protein complex assembly GO:0043623 116 0.080
leukotriene biosynthetic process GO:0019370 5 0.079
positive regulation of proteolysis GO:0045862 85 0.079
membrane lipid metabolic process GO:0006643 53 0.074
glycerolipid biosynthetic process GO:0045017 50 0.074
regulation of apoptotic signaling pathway GO:2001233 197 0.074
gland development GO:0048732 330 0.073
response to organonitrogen compound GO:0010243 246 0.073
response to extracellular stimulus GO:0009991 127 0.073
protein polymerization GO:0051258 57 0.073
hemostasis GO:0007599 78 0.072
cell chemotaxis GO:0060326 81 0.068
regulation of protein kinase activity GO:0045859 232 0.067
small gtpase mediated signal transduction GO:0007264 97 0.066
homotypic cell cell adhesion GO:0034109 28 0.066
regulation of transferase activity GO:0051338 263 0.066
microglia development GO:0014005 2 0.065
regulation of cellular component size GO:0032535 121 0.064
actin polymerization or depolymerization GO:0008154 54 0.064
ras protein signal transduction GO:0007265 77 0.064
blood vessel morphogenesis GO:0048514 285 0.064
regulation of kinase activity GO:0043549 249 0.063
muscle cell differentiation GO:0042692 261 0.063
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.062
intracellular protein transport GO:0006886 204 0.061
fat cell differentiation GO:0045444 160 0.060
regulation of hormone levels GO:0010817 211 0.060
positive regulation of cell activation GO:0050867 158 0.059
regulation of cell migration GO:0030334 219 0.059
response to nutrient levels GO:0031667 109 0.059
unsaturated fatty acid metabolic process GO:0033559 31 0.058
amine metabolic process GO:0009308 45 0.058
regulation of establishment of protein localization GO:0070201 181 0.058
cytokine mediated signaling pathway GO:0019221 115 0.057
negative regulation of cytokine production GO:0001818 84 0.057
negative regulation of cell proliferation GO:0008285 296 0.057
negative regulation of response to wounding GO:1903035 77 0.056
muscle tissue development GO:0060537 308 0.054
organic hydroxy compound metabolic process GO:1901615 203 0.054
response to peptide GO:1901652 136 0.054
positive regulation of programmed cell death GO:0043068 218 0.053
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.053
positive regulation of lymphocyte activation GO:0051251 140 0.053
regulation of vesicle mediated transport GO:0060627 139 0.052
interleukin 10 secretion GO:0072608 4 0.052
positive regulation of protein kinase activity GO:0045860 144 0.052
cell type specific apoptotic process GO:0097285 268 0.051
regulation of endocytosis GO:0030100 69 0.051
regulation of defense response GO:0031347 233 0.051
sphingolipid metabolic process GO:0006665 45 0.050
positive regulation of transferase activity GO:0051347 167 0.050
oxidation reduction process GO:0055114 342 0.049
response to molecule of bacterial origin GO:0002237 143 0.049
anion transmembrane transport GO:0098656 71 0.049
multicellular organismal homeostasis GO:0048871 164 0.049
response to organic cyclic compound GO:0014070 198 0.048
positive regulation of inflammatory response GO:0050729 47 0.048
phospholipid metabolic process GO:0006644 87 0.047
g protein coupled receptor signaling pathway GO:0007186 243 0.047
myotube differentiation GO:0014902 105 0.047
cellular response to biotic stimulus GO:0071216 92 0.046
positive regulation of cytokine production GO:0001819 174 0.046
sensory perception GO:0007600 245 0.046
regulation of lymphocyte activation GO:0051249 240 0.046
cellular response to external stimulus GO:0071496 88 0.045
interspecies interaction between organisms GO:0044419 83 0.045
renal system development GO:0072001 225 0.045
leukocyte chemotaxis GO:0030595 69 0.045
regulation of neurotransmitter levels GO:0001505 87 0.045
b cell activation GO:0042113 161 0.044
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.044
negative regulation of cell activation GO:0050866 111 0.044
cellular response to dna damage stimulus GO:0006974 207 0.043
lymphocyte apoptotic process GO:0070227 54 0.043
lipoxygenase pathway GO:0019372 5 0.043
leukocyte mediated immunity GO:0002443 174 0.042
tube formation GO:0035148 140 0.042
cytokine secretion GO:0050663 72 0.041
positive regulation of apoptotic signaling pathway GO:2001235 95 0.041
glycerophospholipid metabolic process GO:0006650 71 0.041
positive regulation of apoptotic process GO:0043065 217 0.041
endomembrane system organization GO:0010256 147 0.040
leukocyte differentiation GO:0002521 342 0.040
regulation of cytokine production GO:0001817 266 0.040
protein processing GO:0016485 163 0.040
cellular ketone metabolic process GO:0042180 84 0.040
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.040
organonitrogen compound biosynthetic process GO:1901566 192 0.040
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.039
development of primary female sexual characteristics GO:0046545 73 0.039
organonitrogen compound catabolic process GO:1901565 264 0.039
regulation of inflammatory response GO:0050727 147 0.038
production of molecular mediator of immune response GO:0002440 103 0.038
immune effector process GO:0002252 321 0.038
regulation of endopeptidase activity GO:0052548 89 0.038
response to calcium ion GO:0051592 20 0.038
negative regulation of lymphocyte activation GO:0051250 91 0.037
cellular metal ion homeostasis GO:0006875 151 0.037
regulation of alpha beta t cell activation GO:0046634 53 0.037
striated muscle tissue development GO:0014706 293 0.037
actin filament polymerization GO:0030041 44 0.037
neurotransmitter transport GO:0006836 76 0.037
regulation of cytoskeleton organization GO:0051493 122 0.037
syncytium formation by plasma membrane fusion GO:0000768 42 0.037
locomotory behavior GO:0007626 195 0.037
anatomical structure homeostasis GO:0060249 145 0.037
phospholipid biosynthetic process GO:0008654 36 0.037
transmembrane transport GO:0055085 412 0.037
peptidyl amino acid modification GO:0018193 336 0.037
positive regulation of kinase activity GO:0033674 155 0.036
cellular response to calcium ion GO:0071277 14 0.036
cellular response to organonitrogen compound GO:0071417 145 0.036
positive regulation of protein modification process GO:0031401 299 0.036
intrinsic apoptotic signaling pathway GO:0097193 132 0.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.036
cellular response to extracellular stimulus GO:0031668 81 0.036
regulation of secretion by cell GO:1903530 249 0.036
positive regulation of peptidase activity GO:0010952 49 0.036
nucleotide metabolic process GO:0009117 332 0.036
negative regulation of interleukin 10 secretion GO:2001180 2 0.035
regulation of cellular response to stress GO:0080135 159 0.035
regulation of interleukin 10 secretion GO:2001179 4 0.035
glial cell apoptotic process GO:0034349 3 0.035
platelet aggregation GO:0070527 20 0.035
response to inorganic substance GO:0010035 96 0.034
negative regulation of apoptotic signaling pathway GO:2001234 104 0.034
aromatic compound catabolic process GO:0019439 286 0.033
response to lipopolysaccharide GO:0032496 128 0.033
muscle cell development GO:0055001 133 0.033
stem cell differentiation GO:0048863 268 0.033
extracellular matrix organization GO:0030198 147 0.033
regulation of tube size GO:0035150 57 0.033
protein localization to organelle GO:0033365 185 0.033
fatty acid metabolic process GO:0006631 121 0.033
regulation of b cell activation GO:0050864 81 0.033
negative regulation of cell growth GO:0030308 44 0.033
leukotriene metabolic process GO:0006691 7 0.032
actin filament organization GO:0007015 113 0.032
protein import into nucleus GO:0006606 95 0.032
mapk cascade GO:0000165 281 0.032
positive regulation of mapk cascade GO:0043410 170 0.032
regulation of protein localization GO:0032880 231 0.032
cytokine production involved in immune response GO:0002367 34 0.032
organic hydroxy compound transport GO:0015850 93 0.032
skeletal system development GO:0001501 356 0.031
protein ubiquitination GO:0016567 171 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
positive regulation of secretion GO:0051047 130 0.031
cellular response to growth factor stimulus GO:0071363 197 0.031
morphogenesis of a branching structure GO:0001763 203 0.031
single organismal cell cell adhesion GO:0016337 131 0.031
phagocytosis GO:0006909 66 0.031
sensory organ morphogenesis GO:0090596 242 0.031
lymphocyte proliferation GO:0046651 164 0.031
positive regulation of homeostatic process GO:0032846 64 0.031
cell junction organization GO:0034330 77 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
lymphocyte activation involved in immune response GO:0002285 93 0.030
regulation of cellular response to growth factor stimulus GO:0090287 82 0.030
tissue remodeling GO:0048771 102 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
morphogenesis of a polarized epithelium GO:0001738 37 0.030
small molecule biosynthetic process GO:0044283 132 0.030
Human
microglia differentiation GO:0014004 2 0.030
glycerophospholipid biosynthetic process GO:0046474 32 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.029
regulation of peptidase activity GO:0052547 96 0.029
regulation of adaptive immune response GO:0002819 90 0.029
regulation of homotypic cell cell adhesion GO:0034110 13 0.029
negative regulation of cell adhesion GO:0007162 45 0.029
heterocycle catabolic process GO:0046700 280 0.029
negative regulation of cell motility GO:2000146 61 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 2 0.029
regulation of angiogenesis GO:0045765 81 0.029
gtp metabolic process GO:0046039 144 0.029
cellular response to cytokine stimulus GO:0071345 189 0.029
cation transmembrane transport GO:0098655 266 0.029
regulation of epithelial cell proliferation GO:0050678 141 0.029
protein kinase b signaling GO:0043491 74 0.029
positive regulation of type 2 immune response GO:0002830 9 0.029
positive regulation of leukocyte proliferation GO:0070665 73 0.028
monocarboxylic acid transport GO:0015718 44 0.028
negative regulation of t cell activation GO:0050868 65 0.028
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.028
cellular response to hormone stimulus GO:0032870 150 0.028
guanosine containing compound metabolic process GO:1901068 144 0.028
cellular response to organic cyclic compound GO:0071407 87 0.028
organic hydroxy compound biosynthetic process GO:1901617 77 0.028
cell cell junction organization GO:0045216 72 0.028
cell substrate adhesion GO:0031589 130 0.028
positive regulation of neuron differentiation GO:0045666 141 0.027
granulocyte migration GO:0097530 43 0.027
regulation of protein targeting GO:1903533 61 0.027
epithelial tube formation GO:0072175 130 0.027
positive regulation of endopeptidase activity GO:0010950 43 0.027
lipid localization GO:0010876 126 0.027
b cell differentiation GO:0030183 78 0.027
establishment of planar polarity GO:0001736 28 0.027
amino acid transmembrane transport GO:0003333 37 0.027
norepinephrine secretion GO:0048243 2 0.027
protein localization to nucleus GO:0034504 121 0.027
leukocyte proliferation GO:0070661 172 0.027
rho protein signal transduction GO:0007266 32 0.027
gonad development GO:0008406 141 0.027
negative regulation of cellular component organization GO:0051129 194 0.027
regulation of lymphocyte differentiation GO:0045619 107 0.027
regulation of proteolysis GO:0030162 164 0.026
cellular amino acid catabolic process GO:0009063 25 0.026
amino acid transport GO:0006865 61 0.026
smooth muscle contraction GO:0006939 44 0.026
amide transport GO:0042886 138 0.026
regulation of system process GO:0044057 200 0.026
regulation of cell growth GO:0001558 91 0.026
regulation of protein kinase b signaling GO:0051896 56 0.026
regulation of vasculature development GO:1901342 88 0.025
synaptic vesicle localization GO:0097479 59 0.025
homeostasis of number of cells GO:0048872 210 0.025
regulation of mapk cascade GO:0043408 248 0.025
kidney development GO:0001822 213 0.025
positive regulation of leukocyte differentiation GO:1902107 86 0.025
negative regulation of protein modification process GO:0031400 163 0.025
leukocyte activation involved in immune response GO:0002366 126 0.025
regulation of lymphocyte proliferation GO:0050670 117 0.025
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.025
regulation of cellular component biogenesis GO:0044087 181 0.024
regulation of leukocyte differentiation GO:1902105 159 0.024
regulation of leukocyte proliferation GO:0070663 121 0.024
negative regulation of cell substrate adhesion GO:0010812 16 0.024
response to peptide hormone GO:0043434 127 0.024
positive regulation of cell death GO:0010942 224 0.024
regulation of norepinephrine secretion GO:0014061 2 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
thymocyte migration GO:0072679 2 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
cation transport GO:0006812 399 0.024
neurotransmitter secretion GO:0007269 62 0.023
positive regulation of protein kinase b signaling GO:0051897 32 0.023
purine containing compound catabolic process GO:0072523 213 0.023
positive regulation of protein transport GO:0051222 93 0.023
striated muscle cell development GO:0055002 125 0.023
branching morphogenesis of an epithelial tube GO:0048754 159 0.023
glial cell differentiation GO:0010001 131 0.023
bone mineralization GO:0030282 54 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
leukocyte apoptotic process GO:0071887 71 0.023
negative regulation of synapse assembly GO:0051964 3 0.023
cartilage development GO:0051216 140 0.023
regulation of transmembrane transport GO:0034762 128 0.023
regulation of cell substrate adhesion GO:0010810 73 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.023
platelet activation GO:0030168 40 0.023
regulation of water loss via skin GO:0033561 16 0.023
regulation of t cell proliferation GO:0042129 92 0.023
regulation of intracellular transport GO:0032386 159 0.022
kidney morphogenesis GO:0060993 83 0.022
protein maturation GO:0051604 176 0.022
connective tissue development GO:0061448 179 0.022
circadian temperature homeostasis GO:0060086 2 0.022
regionalization GO:0003002 337 0.022
positive regulation of intracellular transport GO:0032388 70 0.022
spermatogenesis GO:0007283 284 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
defense response to virus GO:0051607 68 0.022
positive regulation of t cell activation GO:0050870 101 0.022
neuron death GO:0070997 154 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
lung cell differentiation GO:0060479 30 0.021
leukocyte migration GO:0050900 124 0.021
macromolecule catabolic process GO:0009057 281 0.021
forebrain development GO:0030900 302 0.021
t cell proliferation GO:0042098 120 0.021
positive regulation of lymphocyte differentiation GO:0045621 61 0.021
mesonephric epithelium development GO:0072163 94 0.021
regulation of homeostatic process GO:0032844 182 0.021
protein lipidation GO:0006497 28 0.021
tube closure GO:0060606 91 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
glycoprotein biosynthetic process GO:0009101 89 0.021
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.021
positive regulation of protein catabolic process GO:0045732 60 0.021
myeloid cell homeostasis GO:0002262 114 0.021
protein catabolic process GO:0030163 221 0.021
norepinephrine transport GO:0015874 2 0.021
nephron epithelium development GO:0072009 92 0.021
signal transduction in absence of ligand GO:0038034 55 0.021
regulation of eosinophil migration GO:2000416 2 0.020
neuron neuron synaptic transmission GO:0007270 69 0.020
response to growth factor GO:0070848 198 0.020
skeletal muscle organ development GO:0060538 163 0.020
hair cycle GO:0042633 90 0.020
epidermis development GO:0008544 187 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.020
acid secretion GO:0046717 33 0.020
nitrogen compound transport GO:0071705 271 0.020
neutral lipid metabolic process GO:0006638 57 0.020
regulation of membrane potential GO:0042391 192 0.020
innate immune response GO:0045087 157 0.020
regulation of skeletal muscle fiber development GO:0048742 36 0.020
hepaticobiliary system development GO:0061008 67 0.020
ureteric bud development GO:0001657 94 0.020
regulation of cysteine type endopeptidase activity GO:2000116 65 0.020
calcium ion transport GO:0006816 159 0.020
regulation of phagocytosis engulfment GO:0060099 5 0.020
embryonic epithelial tube formation GO:0001838 130 0.020
dendritic spine maintenance GO:0097062 4 0.019
cellular response to inorganic substance GO:0071241 37 0.019
negative regulation of alpha beta t cell activation GO:0046636 18 0.019
regulation of neuron differentiation GO:0045664 281 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.019
positive regulation of calcium ion transport GO:0051928 27 0.019
cd4 positive alpha beta t cell activation GO:0035710 45 0.019
regulation of cell size GO:0008361 72 0.019
cell matrix adhesion GO:0007160 68 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.019
protein homotrimerization GO:0070207 4 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.019
camera type eye development GO:0043010 266 0.019
positive regulation of thymocyte migration GO:2000412 2 0.019
inner ear morphogenesis GO:0042472 101 0.019
positive regulation of nervous system development GO:0051962 221 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
regeneration GO:0031099 38 0.019
female gonad development GO:0008585 71 0.019
nephron development GO:0072006 109 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.019
positive regulation of leukocyte mediated immunity GO:0002705 70 0.018
b cell activation involved in immune response GO:0002312 50 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
regulation of organ morphogenesis GO:2000027 144 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
germ cell development GO:0007281 185 0.018
plasma membrane organization GO:0007009 90 0.018
acute inflammatory response GO:0002526 41 0.018
endocytosis GO:0006897 168 0.018
cell cell recognition GO:0009988 44 0.018
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.018
regulation of actin cytoskeleton organization GO:0032956 84 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
positive regulation of lymphocyte proliferation GO:0050671 70 0.018
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
ameboidal type cell migration GO:0001667 128 0.018
Zebrafish
maintenance of location GO:0051235 89 0.018
male gamete generation GO:0048232 285 0.018
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.018
negative regulation of coagulation GO:0050819 11 0.018
myeloid leukocyte migration GO:0097529 57 0.018
regulation of protein catabolic process GO:0042176 108 0.017
regulation of protein transport GO:0051223 163 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
negative regulation of neuron apoptotic process GO:0043524 92 0.017
establishment of skin barrier GO:0061436 14 0.017
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.017
cell activation involved in immune response GO:0002263 126 0.017
regulation of actin filament length GO:0030832 45 0.017
positive regulation of organelle organization GO:0010638 128 0.017
rhythmic process GO:0048511 174 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
regulation of protein import into nucleus GO:0042306 52 0.017
nuclear transport GO:0051169 139 0.017
mature dendritic cell differentiation GO:0097029 3 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
single fertilization GO:0007338 82 0.017
icosanoid secretion GO:0032309 12 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.017
response to transforming growth factor beta GO:0071559 88 0.017
regulation of thymocyte migration GO:2000410 2 0.017
chemokine production GO:0032602 34 0.017
trunk neural crest cell migration GO:0036484 4 0.017
metal ion homeostasis GO:0055065 189 0.017
regulation of interleukin 6 production GO:0032675 55 0.017
cognition GO:0050890 149 0.017
t cell differentiation in thymus GO:0033077 77 0.017
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.017
interleukin 6 production GO:0032635 58 0.017
male gonad development GO:0008584 88 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
compound eye development GO:0048749 1 0.017
myeloid cell differentiation GO:0030099 233 0.017
negative regulation of protein processing GO:0010955 79 0.017
lung development GO:0030324 164 0.017
positive regulation of killing of cells of other organism GO:0051712 3 0.017
regulation of extent of cell growth GO:0061387 52 0.017
interleukin 8 production GO:0032637 4 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
regulation of alpha beta t cell differentiation GO:0046637 35 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
nucleoside metabolic process GO:0009116 246 0.016
leukocyte homeostasis GO:0001776 79 0.016
transmission of nerve impulse GO:0019226 76 0.016
regulation of cytokine secretion involved in immune response GO:0002739 4 0.016
respiratory tube development GO:0030323 167 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
negative regulation of wound healing GO:0061045 14 0.016
bone resorption GO:0045453 38 0.016
protein localization to plasma membrane GO:0072659 57 0.016
response to steroid hormone GO:0048545 56 0.016
positive regulation of alpha beta t cell activation GO:0046635 39 0.016
cell growth GO:0016049 130 0.016
response to increased oxygen levels GO:0036296 2 0.016
divalent metal ion transport GO:0070838 172 0.016
neutrophil chemotaxis GO:0030593 36 0.016
embryonic appendage morphogenesis GO:0035113 126 0.016
cytoplasmic transport GO:0016482 234 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
negative regulation of multi organism process GO:0043901 68 0.016
protein localization to membrane GO:0072657 108 0.016
response to radiation GO:0009314 165 0.016
response to insulin GO:0032868 100 0.016
protein targeting GO:0006605 143 0.016

Ptges disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.018