Mus musculus

210 known processes

Ptk2

PTK2 protein tyrosine kinase 2

(Aliases: Fadk,FAK,mKIAA4203,FRNK,KIAA4203)

Ptk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
b cell receptor signaling pathway GO:0050853 20 0.996
single organism cell adhesion GO:0098602 156 0.995
Human
cell adhesion GO:0007155 329 0.994
Human Rat
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.993
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.992
olfactory learning GO:0008355 2 0.988
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.988
activation of immune response GO:0002253 138 0.979
substrate adhesion dependent cell spreading GO:0034446 30 0.976
immune response activating signal transduction GO:0002757 116 0.976
single organismal cell cell adhesion GO:0016337 131 0.973
Human
regulation of phospholipase c activity GO:1900274 3 0.973
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.972
regulation of cell adhesion GO:0030155 154 0.971
Human Rat
peptidyl tyrosine phosphorylation GO:0018108 143 0.967
regulation of protein serine threonine kinase activity GO:0071900 157 0.967
Fly
cellular response to growth factor stimulus GO:0071363 197 0.966
regulation of ion homeostasis GO:2000021 64 0.963
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.954
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.953
wnt signaling pathway GO:0016055 188 0.952
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.951
Human Mouse Fly
regulation of lipase activity GO:0060191 15 0.949
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.941
positive regulation of cell development GO:0010720 237 0.940
Rat
response to hepatocyte growth factor GO:0035728 2 0.938
morphogenesis of a branching epithelium GO:0061138 193 0.938
ameboidal type cell migration GO:0001667 128 0.937
positive regulation of cell projection organization GO:0031346 95 0.934
positive regulation of mapk cascade GO:0043410 170 0.933
response to growth factor GO:0070848 198 0.931
positive regulation of cell motility GO:2000147 116 0.931
Human Mouse Rat
antigen receptor mediated signaling pathway GO:0050851 64 0.931
cell junction organization GO:0034330 77 0.930
tissue migration GO:0090130 68 0.922
cell chemotaxis GO:0060326 81 0.922
Mouse
immune response regulating signaling pathway GO:0002764 125 0.922
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.920
synapse organization GO:0050808 125 0.920
regulation of cell motility GO:2000145 236 0.920
Human Mouse Rat
regulation of mast cell activation GO:0033003 21 0.919
phagocytosis GO:0006909 66 0.916
Rat
cell junction assembly GO:0034329 52 0.915
rho protein signal transduction GO:0007266 32 0.912
morphogenesis of a polarized epithelium GO:0001738 37 0.908
peptidyl tyrosine modification GO:0018212 145 0.907
regulation of cellular amine metabolic process GO:0033238 20 0.906
regulation of rho protein signal transduction GO:0035023 71 0.900
regulation of cell migration GO:0030334 219 0.898
Human Mouse Rat
t cell activation GO:0042110 289 0.898
insulin receptor signaling pathway GO:0008286 49 0.895
formation of radial glial scaffolds GO:0021943 4 0.885
blood vessel morphogenesis GO:0048514 285 0.885
establishment or maintenance of cell polarity GO:0007163 86 0.885
Mouse
neuron recognition GO:0008038 25 0.884
regulation of protein autophosphorylation GO:0031952 8 0.884
positive regulation of lipid kinase activity GO:0090218 11 0.883
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.883
neuron migration GO:0001764 122 0.880
regulation of cell projection organization GO:0031344 206 0.880
integrin mediated signaling pathway GO:0007229 27 0.876
Human
purine ribonucleoside catabolic process GO:0046130 205 0.873
regulation of cellular ketone metabolic process GO:0010565 66 0.868
regulation of transferase activity GO:0051338 263 0.868
Human Mouse Fly
epithelial tube morphogenesis GO:0060562 303 0.866
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.864
Fly
endothelial cell migration GO:0043542 44 0.864
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.858
Human
regulation of mapk cascade GO:0043408 248 0.857
Fly
cell cell junction organization GO:0045216 72 0.850
positive regulation of kinase activity GO:0033674 155 0.849
Human Mouse
positive regulation of neuron projection development GO:0010976 79 0.848
urogenital system development GO:0001655 261 0.842
actin cytoskeleton organization GO:0030036 220 0.837
Mouse
positive regulation of cell migration GO:0030335 109 0.827
Human Mouse Rat
gastrulation GO:0007369 116 0.821
positive regulation of epithelial cell migration GO:0010634 19 0.817
Mouse
epithelial cell migration GO:0010631 63 0.814
regulation of cellular amino acid metabolic process GO:0006521 5 0.813
extrinsic apoptotic signaling pathway GO:0097191 126 0.813
membrane invagination GO:0010324 17 0.811
release of sequestered calcium ion into cytosol GO:0051209 42 0.804
Mouse
regulation of actin filament based process GO:0032970 99 0.800
Mouse
negative regulation of rho protein signal transduction GO:0035024 7 0.800
neurotrophin trk receptor signaling pathway GO:0048011 8 0.795
substrate dependent cell migration cell extension GO:0006930 4 0.788
regulation of cytoskeleton organization GO:0051493 122 0.784
Mouse
positive regulation of nervous system development GO:0051962 221 0.783
Rat
dna metabolic process GO:0006259 303 0.778
morphogenesis of a branching structure GO:0001763 203 0.771
spermatogenesis GO:0007283 284 0.769
divalent inorganic cation homeostasis GO:0072507 138 0.763
Mouse
cellular lipid metabolic process GO:0044255 323 0.761
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.760
regulation of mast cell activation involved in immune response GO:0033006 17 0.760
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.751
membrane organization GO:0061024 245 0.746
regulation of axon extension GO:0030516 43 0.746
axonogenesis GO:0007409 274 0.740
negative regulation of cellular component organization GO:0051129 194 0.737
associative learning GO:0008306 61 0.736
positive regulation of intracellular transport GO:0032388 70 0.733
substrate dependent cell migration GO:0006929 18 0.732
cellular homeostasis GO:0019725 240 0.730
Mouse Rat
chemotaxis GO:0006935 247 0.729
Mouse
amine metabolic process GO:0009308 45 0.728
regulation of actin cytoskeleton organization GO:0032956 84 0.718
Mouse
positive regulation of protein modification process GO:0031401 299 0.718
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.711
sequestering of metal ion GO:0051238 19 0.710
focal adhesion assembly GO:0048041 19 0.710
negative regulation of phosphorylation GO:0042326 166 0.703
Fly
response to organonitrogen compound GO:0010243 246 0.702
Human Rat
positive regulation of endothelial cell migration GO:0010595 12 0.701
Mouse
negative regulation of synapse assembly GO:0051964 3 0.699
regulation of protein kinase activity GO:0045859 232 0.696
Human Mouse Fly
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.694
salivary gland development GO:0007431 37 0.691
regulation of engulfment of apoptotic cell GO:1901074 2 0.689
regulation of insulin receptor signaling pathway GO:0046626 21 0.686
purine nucleotide metabolic process GO:0006163 302 0.685
Mouse
actin filament organization GO:0007015 113 0.683
cellular response to insulin stimulus GO:0032869 78 0.678
actin polymerization or depolymerization GO:0008154 54 0.675
gland development GO:0048732 330 0.674
cellular response to hormone stimulus GO:0032870 150 0.673
Human
positive regulation of phospholipase c activity GO:0010863 2 0.668
endocytosis GO:0006897 168 0.667
Rat
spindle localization GO:0051653 22 0.666
cellular response to lipid GO:0071396 145 0.664
forebrain cell migration GO:0021885 58 0.662
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.662
epithelial cell development GO:0002064 159 0.661
Zebrafish
lymphocyte differentiation GO:0030098 242 0.657
Mouse
response to peptide hormone GO:0043434 127 0.657
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.655
endodermal cell fate specification GO:0001714 4 0.654
cellular response to peptide GO:1901653 92 0.654
Human
organic cyclic compound catabolic process GO:1901361 295 0.653
cellular response to peptide hormone stimulus GO:0071375 92 0.652
Human
formation of primary germ layer GO:0001704 77 0.650
positive regulation of neuron differentiation GO:0045666 141 0.648
negative regulation of protein modification process GO:0031400 163 0.646
Fly
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.645
ribonucleotide catabolic process GO:0009261 208 0.644
positive regulation of cell adhesion GO:0045785 80 0.642
Rat
response to peptide GO:1901652 136 0.637
Human
positive regulation of wnt signaling pathway GO:0030177 45 0.635
cellular ketone metabolic process GO:0042180 84 0.625
cell growth GO:0016049 130 0.620
Mouse Rat
protein localization to organelle GO:0033365 185 0.618
epithelial cell proliferation GO:0050673 174 0.617
regulation of cellular catabolic process GO:0031329 242 0.617
positive regulation of cellular amine metabolic process GO:0033240 5 0.615
negative regulation of nervous system development GO:0051961 156 0.614
intracellular protein transport GO:0006886 204 0.614
b cell proliferation GO:0042100 53 0.612
myotube differentiation GO:0014902 105 0.605
purine nucleotide catabolic process GO:0006195 211 0.604
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.602
telencephalon development GO:0021537 186 0.601
digestive tract morphogenesis GO:0048546 147 0.598
regulation of rho gtpase activity GO:0032319 58 0.595
telencephalon cell migration GO:0022029 55 0.594
actin filament bundle assembly GO:0051017 40 0.593
mesenchyme development GO:0060485 152 0.590
neuron projection guidance GO:0097485 141 0.589
neural precursor cell proliferation GO:0061351 121 0.584
regulation of phagocytosis GO:0050764 33 0.580
Rat
embryonic organ morphogenesis GO:0048562 276 0.576
nucleoside phosphate catabolic process GO:1901292 222 0.576
negative regulation of kinase activity GO:0033673 81 0.575
Fly
mapk cascade GO:0000165 281 0.575
Rat Fly
regulation of kinase activity GO:0043549 249 0.574
Human Mouse Fly
muscle cell differentiation GO:0042692 261 0.572
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 5 0.570
regulation of neuron projection development GO:0010975 169 0.564
neurotrophin signaling pathway GO:0038179 12 0.559
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.558
Mouse
cell type specific apoptotic process GO:0097285 268 0.552
organonitrogen compound catabolic process GO:1901565 264 0.545
regulation of anatomical structure size GO:0090066 178 0.544
Rat
epithelium migration GO:0090132 63 0.542
cell recognition GO:0008037 83 0.535
sprouting angiogenesis GO:0002040 26 0.534
Mouse
angiogenesis GO:0001525 201 0.528
nucleotide catabolic process GO:0009166 217 0.528
cell substrate junction assembly GO:0007044 24 0.527
homotypic cell cell adhesion GO:0034109 28 0.527
i kappab kinase nf kappab signaling GO:0007249 85 0.526
sequestering of calcium ion GO:0051208 18 0.522
salivary gland morphogenesis GO:0007435 33 0.514
digestive tract development GO:0048565 190 0.512
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.509
negative regulation of cell adhesion GO:0007162 45 0.508
Human
cell substrate adhesion GO:0031589 130 0.504
cytosolic calcium ion transport GO:0060401 48 0.504
Mouse
male gamete generation GO:0048232 285 0.501
protein catabolic process GO:0030163 221 0.498
adherens junction assembly GO:0034333 22 0.493
cellular amine metabolic process GO:0044106 44 0.491
response to insulin GO:0032868 100 0.488
positive regulation of map kinase activity GO:0043406 84 0.487
cellular amino acid metabolic process GO:0006520 103 0.485
regulation of cytoplasmic transport GO:1903649 112 0.483
Mouse
regulation of synaptic plasticity GO:0048167 87 0.479
syncytium formation by plasma membrane fusion GO:0000768 42 0.479
b cell homeostasis GO:0001782 34 0.479
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.478
regulation of intracellular transport GO:0032386 159 0.478
Mouse
regulation of actin filament length GO:0030832 45 0.477
leukocyte cell cell adhesion GO:0007159 14 0.473
purine containing compound metabolic process GO:0072521 311 0.473
Mouse
leukocyte differentiation GO:0002521 342 0.473
Mouse
endocardium development GO:0003157 10 0.472
engulfment of apoptotic cell GO:0043652 3 0.472
regulation of erk1 and erk2 cascade GO:0070372 71 0.471
negative regulation of cell proliferation GO:0008285 296 0.471
cellular metal ion homeostasis GO:0006875 151 0.470
Mouse
gliogenesis GO:0042063 141 0.469
Rat
germ cell development GO:0007281 185 0.467
macromolecule catabolic process GO:0009057 281 0.464
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.459
negative regulation of cell projection organization GO:0031345 56 0.459
cellular chemical homeostasis GO:0055082 215 0.458
Mouse Rat
cation homeostasis GO:0055080 212 0.458
Mouse
embryonic placenta development GO:0001892 98 0.457
myeloid leukocyte differentiation GO:0002573 119 0.457
response to alcohol GO:0097305 48 0.457
Rat
regulation of protein localization GO:0032880 231 0.455
liver development GO:0001889 66 0.454
activation of mapk activity GO:0000187 59 0.453
positive regulation of rho gtpase activity GO:0032321 41 0.450
negative regulation of epithelial cell proliferation GO:0050680 64 0.449
positive regulation of protein localization to nucleus GO:1900182 30 0.440
heart morphogenesis GO:0003007 178 0.438
lymphocyte homeostasis GO:0002260 64 0.437
regulation of neuron differentiation GO:0045664 281 0.434
leukocyte degranulation GO:0043299 27 0.434
purine nucleoside metabolic process GO:0042278 241 0.431
apoptotic signaling pathway GO:0097190 306 0.431
cerebellum development GO:0021549 77 0.431
regulated secretory pathway GO:0045055 32 0.430
regionalization GO:0003002 337 0.419
regulation of defense response GO:0031347 233 0.412
regulation of homeostatic process GO:0032844 182 0.412
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.411
Human
blood vessel endothelial cell migration GO:0043534 23 0.409
microtubule cytoskeleton organization GO:0000226 157 0.407
dna recombination GO:0006310 92 0.405
learning GO:0007612 98 0.404
nucleoside triphosphate metabolic process GO:0009141 230 0.403
regulation of mast cell degranulation GO:0043304 16 0.402
cellular response to biotic stimulus GO:0071216 92 0.402
positive regulation of cellular component biogenesis GO:0044089 94 0.401
ribonucleoside catabolic process GO:0042454 206 0.400
spermatid differentiation GO:0048515 115 0.400
organophosphate catabolic process GO:0046434 232 0.399
metal ion homeostasis GO:0055065 189 0.393
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.393
Mouse
hindbrain radial glia guided cell migration GO:0021932 12 0.392
inflammatory response GO:0006954 244 0.391
regulation of gamma delta t cell activation GO:0046643 9 0.390
cytoplasmic transport GO:0016482 234 0.388
Mouse
ribose phosphate metabolic process GO:0019693 291 0.384
Mouse
regulation of hydrolase activity GO:0051336 246 0.384
positive regulation of phospholipase activity GO:0010518 3 0.379
negative regulation of cellular protein metabolic process GO:0032269 247 0.376
Fly
lens development in camera type eye GO:0002088 62 0.376
Zebrafish
ribonucleotide metabolic process GO:0009259 291 0.375
Mouse
regulation of regulated secretory pathway GO:1903305 20 0.369
t cell proliferation GO:0042098 120 0.368
ras protein signal transduction GO:0007265 77 0.365
Mouse
immune effector process GO:0002252 321 0.364
Mouse
forebrain development GO:0030900 302 0.363
organelle localization GO:0051640 179 0.361
positive regulation of protein kinase activity GO:0045860 144 0.361
Human Mouse
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.358
mast cell proliferation GO:0070662 4 0.356
learning or memory GO:0007611 148 0.355
response to molecule of bacterial origin GO:0002237 143 0.354
transmission of nerve impulse GO:0019226 76 0.352
digestive system development GO:0055123 200 0.351
camera type eye development GO:0043010 266 0.350
Zebrafish
regulation of organelle organization GO:0033043 289 0.347
Mouse
hindbrain development GO:0030902 128 0.347
embryonic heart tube development GO:0035050 65 0.346
synaptic transmission GO:0007268 329 0.344
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.342
establishment of organelle localization GO:0051656 122 0.342
regulation of cell projection assembly GO:0060491 38 0.341
t cell differentiation GO:0030217 174 0.340
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.340
regulation of lymphocyte proliferation GO:0050670 117 0.339
calcium ion transport GO:0006816 159 0.338
Mouse
regulation of ras gtpase activity GO:0032318 88 0.335
toll like receptor 2 signaling pathway GO:0034134 6 0.333
heterocycle catabolic process GO:0046700 280 0.333
regulation of ras protein signal transduction GO:0046578 114 0.332
Mouse
calcium ion homeostasis GO:0055074 127 0.331
Mouse
myeloid cell differentiation GO:0030099 233 0.327
positive regulation of cell death GO:0010942 224 0.326
neuron apoptotic process GO:0051402 142 0.323
cellular response to lipopolysaccharide GO:0071222 77 0.318
jnk cascade GO:0007254 72 0.317
Rat
negative regulation of transferase activity GO:0051348 85 0.317
Fly
negative regulation of neuron projection regeneration GO:0070571 3 0.317
response to transforming growth factor beta GO:0071559 88 0.314
cation transport GO:0006812 399 0.313
Mouse
positive regulation of smooth muscle cell migration GO:0014911 4 0.312
Rat
synaptic growth at neuromuscular junction GO:0051124 6 0.312
Fly
multicellular organism growth GO:0035264 161 0.310
cellular response to radiation GO:0071478 28 0.309
regulation of protein transport GO:0051223 163 0.309
cell substrate adherens junction assembly GO:0007045 19 0.308
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.308
regulation of map kinase activity GO:0043405 120 0.307
Fly
mast cell activation involved in immune response GO:0002279 20 0.306
purine ribonucleotide catabolic process GO:0009154 208 0.305
regulation of hepatocyte proliferation GO:2000345 6 0.303
pallium development GO:0021543 120 0.302
cell activation involved in immune response GO:0002263 126 0.302
Mouse
calcium ion transport into cytosol GO:0060402 48 0.300
Mouse
regulation of endocytosis GO:0030100 69 0.300
Rat
interleukin 2 secretion GO:0070970 7 0.300
regulation of calcium ion transport GO:0051924 69 0.298
Mouse
vesicle localization GO:0051648 86 0.297
regulation of calcium ion transport into cytosol GO:0010522 31 0.296
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.295
regulation of lymphocyte apoptotic process GO:0070228 41 0.294
cellular response to molecule of bacterial origin GO:0071219 83 0.294
negative regulation of growth GO:0045926 99 0.294
endothelial cell differentiation GO:0045446 41 0.293
negative regulation of apoptotic signaling pathway GO:2001234 104 0.293
positive regulation of intracellular protein transport GO:0090316 42 0.293
regulation of metal ion transport GO:0010959 106 0.293
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.293
response to oxidative stress GO:0006979 123 0.291
morphogenesis of embryonic epithelium GO:0016331 159 0.290
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.287
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.287
regulation of cellular component biogenesis GO:0044087 181 0.285
nucleocytoplasmic transport GO:0006913 139 0.283
sensory perception of pain GO:0019233 47 0.280
regulation of cell shape GO:0008360 39 0.280
Human Mouse Fly
nucleoside phosphate metabolic process GO:0006753 338 0.280
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.277
aromatic compound catabolic process GO:0019439 286 0.275
positive regulation of gtpase activity GO:0043547 85 0.273
detection of abiotic stimulus GO:0009582 60 0.272
regulation of lipid metabolic process GO:0019216 118 0.271
Mouse
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.271
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.268
renal system development GO:0072001 225 0.267
cardiac muscle cell differentiation GO:0055007 69 0.265
regulation of canonical wnt signaling pathway GO:0060828 82 0.263
mast cell mediated immunity GO:0002448 20 0.262
glial cell differentiation GO:0010001 131 0.262
platelet aggregation GO:0070527 20 0.261
positive regulation of cellular catabolic process GO:0031331 148 0.261
dendritic spine maintenance GO:0097062 4 0.261
regeneration GO:0031099 38 0.261
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.259
axon guidance GO:0007411 141 0.259
gtp metabolic process GO:0046039 144 0.259
regulation of vesicle mediated transport GO:0060627 139 0.258
Rat
somite development GO:0061053 81 0.254
regulation of podosome assembly GO:0071801 3 0.254
cardiac muscle tissue development GO:0048738 130 0.251
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.251
canonical wnt signaling pathway GO:0060070 130 0.249
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.248
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.247
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.247
Human
epithelial cell morphogenesis GO:0003382 41 0.247
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.246
negative regulation of ras protein signal transduction GO:0046580 18 0.245
Mouse
mesoderm development GO:0007498 100 0.243
cardiac endothelial cell differentiation GO:0003348 4 0.242
alpha beta t cell activation GO:0046631 91 0.241
regulation of actin polymerization or depolymerization GO:0008064 45 0.241
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.241
erbb signaling pathway GO:0038127 32 0.240
Fly
regulation of chemotaxis GO:0050920 53 0.239
Mouse
nitrogen compound transport GO:0071705 271 0.239
cardiac chamber development GO:0003205 108 0.238
detection of external stimulus GO:0009581 61 0.237
regulation of leukocyte mediated immunity GO:0002703 104 0.236
positive regulation of protein export from nucleus GO:0046827 4 0.236
regulation of system process GO:0044057 200 0.236
Rat
cellular calcium ion homeostasis GO:0006874 119 0.236
Mouse
glycosyl compound metabolic process GO:1901657 246 0.235
regulation of innate immune response GO:0045088 91 0.235
regulation of cell growth GO:0001558 91 0.232
Mouse Rat
gtp catabolic process GO:0006184 143 0.232
sensory perception GO:0007600 245 0.231
positive regulation of chemotaxis GO:0050921 38 0.231
Mouse
endoderm development GO:0007492 45 0.230
regulation of membrane potential GO:0042391 192 0.230
alpha beta t cell differentiation GO:0046632 69 0.230
cellular ion homeostasis GO:0006873 165 0.228
Mouse Rat
positive regulation of cytokine secretion GO:0050715 41 0.228
ossification GO:0001503 216 0.227
Human Mouse
regulation of neuron projection regeneration GO:0070570 7 0.225
regulation of ion transport GO:0043269 215 0.225
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.224
Fly
bmp signaling pathway GO:0030509 93 0.224
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.224
purine containing compound catabolic process GO:0072523 213 0.224
response to monosaccharide GO:0034284 67 0.222
Rat
positive regulation of interferon gamma secretion GO:1902715 3 0.221
cell fate commitment GO:0045165 210 0.220
neuron projection regeneration GO:0031102 14 0.220
glucose transport GO:0015758 56 0.218
regulation of endothelial cell apoptotic process GO:2000351 9 0.213
regulation of cellular component size GO:0032535 121 0.213
regulation of t cell differentiation GO:0045580 83 0.213
establishment of protein localization to organelle GO:0072594 118 0.212
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.212
circulatory system process GO:0003013 197 0.212
Rat
kidney development GO:0001822 213 0.211
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.211
Mouse
response to platelet derived growth factor GO:0036119 6 0.211
regulation of t cell activation GO:0050863 170 0.210
positive regulation of transferase activity GO:0051347 167 0.210
Human Mouse
regulation of blood coagulation GO:0030193 28 0.210
regulation of receptor activity GO:0010469 41 0.209
regulation of phagocytosis engulfment GO:0060099 5 0.209
positive regulation of axon extension GO:0045773 20 0.209
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.208
organelle assembly GO:0070925 177 0.208
developmental growth involved in morphogenesis GO:0060560 138 0.208
cellular nitrogen compound catabolic process GO:0044270 280 0.207
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.206
positive regulation of protein phosphorylation GO:0001934 242 0.206
Human Mouse
neuron projection extension GO:1990138 64 0.206
cardiac chamber morphogenesis GO:0003206 93 0.203
regulation of cellular response to stress GO:0080135 159 0.203
divalent metal ion transport GO:0070838 172 0.200
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.200
Fly
rhodopsin mediated signaling pathway GO:0016056 4 0.199
nucleotide metabolic process GO:0009117 332 0.198
Mouse
lymphocyte proliferation GO:0046651 164 0.198
positive regulation of angiogenesis GO:0045766 46 0.198
Mouse
negative regulation of fat cell differentiation GO:0045599 36 0.197
tissue remodeling GO:0048771 102 0.196
Mouse
cellular protein catabolic process GO:0044257 155 0.196
regulation of body fluid levels GO:0050878 162 0.194
positive regulation of protein transport GO:0051222 93 0.194
positive regulation of podosome assembly GO:0071803 3 0.194
regulation of fat cell differentiation GO:0045598 81 0.193
cellular divalent inorganic cation homeostasis GO:0072503 127 0.192
Mouse
axonal fasciculation GO:0007413 15 0.190
embryonic viscerocranium morphogenesis GO:0048703 8 0.190
dendrite development GO:0016358 115 0.190
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.190
ear development GO:0043583 200 0.190
mitochondrion organization GO:0007005 134 0.189
positive regulation of programmed cell death GO:0043068 218 0.189
retina vasculature development in camera type eye GO:0061298 17 0.186
thymus development GO:0048538 41 0.185
axon regeneration GO:0031103 12 0.185
negative regulation of cellular amine metabolic process GO:0033239 1 0.185
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.181
multicellular organismal homeostasis GO:0048871 164 0.181
Mouse
negative regulation of anoikis GO:2000811 2 0.181
Human
cytosolic calcium ion homeostasis GO:0051480 70 0.181
Mouse
negative regulation of cell development GO:0010721 169 0.180
defense response to bacterium GO:0042742 119 0.178
regulation of exocytosis GO:0017157 61 0.178
filtration diaphragm assembly GO:0036058 1 0.177
positive regulation of hydrolase activity GO:0051345 148 0.176
positive regulation of innate immune response GO:0045089 80 0.176
positive regulation of cell growth GO:0030307 33 0.176
Rat
autophagy GO:0006914 45 0.176
peptidyl amino acid modification GO:0018193 336 0.175
mesoderm morphogenesis GO:0048332 64 0.175
cardiocyte differentiation GO:0035051 87 0.174
hippocampus development GO:0021766 52 0.173
carbohydrate transport GO:0008643 62 0.171
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.168
cardiac ventricle development GO:0003231 83 0.168
prostate gland epithelium morphogenesis GO:0060740 31 0.167
regulation of cell aging GO:0090342 9 0.167
ribonucleoside triphosphate metabolic process GO:0009199 220 0.165
protein modification by small protein conjugation or removal GO:0070647 207 0.165
regulation of organ morphogenesis GO:2000027 144 0.164
epidermal growth factor receptor signaling pathway GO:0007173 28 0.163
Fly
endothelium development GO:0003158 45 0.161
regulation of epithelial cell migration GO:0010632 35 0.161
Mouse
regulation of protein secretion GO:0050708 82 0.159
fc receptor mediated inhibitory signaling pathway GO:0002774 1 0.159
negative regulation of phosphorus metabolic process GO:0010563 184 0.158
Fly
syncytium formation GO:0006949 43 0.158
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.158

Ptk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.169
nervous system disease DOID:863 0 0.169