Mus musculus

15 known processes

Ptma

prothymosin alpha

(Aliases: MGC102090,MGC103390,Thym)

Ptma biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of glycogen catabolic process GO:0005981 2 0.952
negative regulation of phagocytosis GO:0050765 4 0.879
cellular polysaccharide catabolic process GO:0044247 5 0.714
positive regulation of glycogen catabolic process GO:0045819 2 0.605
mrna metabolic process GO:0016071 84 0.532
negative regulation of apoptotic cell clearance GO:2000426 1 0.494
positive regulation of rna splicing GO:0033120 12 0.465
rna splicing GO:0008380 54 0.401
macromolecule catabolic process GO:0009057 281 0.401
mrna processing GO:0006397 63 0.375
glucan catabolic process GO:0009251 5 0.363
gonad development GO:0008406 141 0.361
energy derivation by oxidation of organic compounds GO:0015980 77 0.344
cellular polysaccharide metabolic process GO:0044264 38 0.329
positive regulation of mrna metabolic process GO:1903313 17 0.321
cellular response to dna damage stimulus GO:0006974 207 0.312
regulation of mrna metabolic process GO:1903311 43 0.295
regulation of mrna splicing via spliceosome GO:0048024 32 0.285
cellular glucan metabolic process GO:0006073 32 0.285
regulation of mrna processing GO:0050684 41 0.261
glucan metabolic process GO:0044042 32 0.252
dna metabolic process GO:0006259 303 0.247
positive regulation of mrna processing GO:0050685 16 0.233
polysaccharide metabolic process GO:0005976 39 0.232
negative regulation of rna splicing GO:0033119 12 0.219
carbohydrate metabolic process GO:0005975 230 0.213
posttranscriptional regulation of gene expression GO:0010608 155 0.206
cellular carbohydrate metabolic process GO:0044262 119 0.201
negative regulation of b cell differentiation GO:0045578 4 0.199
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.184
regulation of rna splicing GO:0043484 37 0.183
gene silencing GO:0016458 38 0.181
nucleic acid transport GO:0050657 18 0.172
glycogen metabolic process GO:0005977 32 0.171
oocyte construction GO:0007308 2 0.165
negative regulation of cellular component organization GO:0051129 194 0.164
lung development GO:0030324 164 0.163
development of primary sexual characteristics GO:0045137 143 0.163
microtubule cytoskeleton organization GO:0000226 157 0.152
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.151
cellular response to cytokine stimulus GO:0071345 189 0.150
translation GO:0006412 93 0.149
gene silencing by mirna GO:0035195 10 0.146
positive regulation of glucose metabolic process GO:0010907 21 0.145
respiratory tube development GO:0030323 167 0.127
mrna splicing via spliceosome GO:0000398 43 0.127
gene silencing by rna GO:0031047 19 0.126
posttranscriptional gene silencing by rna GO:0035194 10 0.125
regulation of glycogen metabolic process GO:0070873 13 0.111
regulation of b cell differentiation GO:0045577 23 0.109
fatty acid metabolic process GO:0006631 121 0.108
respiratory system development GO:0060541 190 0.107
regulation of lymphocyte activation GO:0051249 240 0.107
cellular response to interleukin 4 GO:0071353 21 0.106
regulation of cellular component biogenesis GO:0044087 181 0.105
covalent chromatin modification GO:0016569 163 0.104
rna splicing via transesterification reactions GO:0000375 43 0.103
positive regulation of carbohydrate metabolic process GO:0045913 30 0.101
regulation of polysaccharide metabolic process GO:0032881 13 0.101
modification dependent macromolecule catabolic process GO:0043632 133 0.099
negative regulation of mrna processing GO:0050686 12 0.097
dna repair GO:0006281 107 0.097
spermatid development GO:0007286 108 0.095
transcription coupled nucleotide excision repair GO:0006283 2 0.093
glucose metabolic process GO:0006006 92 0.090
viral process GO:0016032 41 0.090
ossification GO:0001503 216 0.088
translesion synthesis GO:0019985 1 0.084
regulation of cellular catabolic process GO:0031329 242 0.083
regulation of carbohydrate catabolic process GO:0043470 12 0.078
energy reserve metabolic process GO:0006112 39 0.078
generation of precursor metabolites and energy GO:0006091 103 0.076
regulation of mitotic cell cycle GO:0007346 126 0.076
positive regulation of protein modification process GO:0031401 299 0.074
leukocyte differentiation GO:0002521 342 0.074
cellular response to organic cyclic compound GO:0071407 87 0.073
monosaccharide metabolic process GO:0005996 106 0.073
negative regulation of b cell activation GO:0050869 27 0.071
rna processing GO:0006396 105 0.071
organic acid biosynthetic process GO:0016053 86 0.071
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.069
regulation of lymphocyte differentiation GO:0045619 107 0.069
negative regulation of endocytosis GO:0045806 12 0.069
regulation of apoptotic signaling pathway GO:2001233 197 0.069
negative regulation of lymphocyte differentiation GO:0045620 32 0.066
oxidation reduction process GO:0055114 342 0.065
negative regulation of cell activation GO:0050866 111 0.064
microtubule based process GO:0007017 236 0.064
response to organic cyclic compound GO:0014070 198 0.063
negative regulation of lymphocyte activation GO:0051250 91 0.062
negative regulation of myeloid cell differentiation GO:0045638 38 0.061
regulation of mrna stability GO:0043488 23 0.061
polysaccharide catabolic process GO:0000272 5 0.060
male gamete generation GO:0048232 285 0.060
spermatogenesis GO:0007283 284 0.060
germ cell development GO:0007281 185 0.059
positive regulation of glycogen metabolic process GO:0070875 8 0.057
regulation of glucose metabolic process GO:0010906 60 0.057
chromatin organization GO:0006325 206 0.056
3 utr mediated mrna stabilization GO:0070935 2 0.056
negative regulation of molecular function GO:0044092 258 0.056
regulation of cell activation GO:0050865 289 0.054
b cell differentiation GO:0030183 78 0.053
posttranscriptional gene silencing GO:0016441 10 0.051
b cell activation GO:0042113 161 0.051
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.051
rna interference GO:0016246 2 0.051
mrna catabolic process GO:0006402 22 0.050
genitalia development GO:0048806 37 0.049
regulation of carbohydrate metabolic process GO:0006109 75 0.049
multicellular organism growth GO:0035264 161 0.047
negative regulation of leukocyte differentiation GO:1902106 51 0.047
lymphocyte differentiation GO:0030098 242 0.046
rna localization GO:0006403 23 0.046
cellular amino acid metabolic process GO:0006520 103 0.046
organophosphate catabolic process GO:0046434 232 0.045
regulation of endocytosis GO:0030100 69 0.044
response to steroid hormone GO:0048545 56 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.044
response to glucocorticoid GO:0051384 20 0.044
response to lipopolysaccharide GO:0032496 128 0.043
regulation of protein kinase activity GO:0045859 232 0.043
regulation of phagocytosis GO:0050764 33 0.043
negative regulation of nucleotide metabolic process GO:0045980 16 0.042
cellular ketone metabolic process GO:0042180 84 0.042
spermatid differentiation GO:0048515 115 0.042
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.041
response to corticosteroid GO:0031960 20 0.041
regulation of myeloid cell differentiation GO:0045637 96 0.041
hexose metabolic process GO:0019318 98 0.041
circulatory system process GO:0003013 197 0.040
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
rna transport GO:0050658 18 0.039
cellular response to lipid GO:0071396 145 0.038
regulation of microtubule based process GO:0032886 52 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
regulation of transferase activity GO:0051338 263 0.037
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.037
aromatic compound catabolic process GO:0019439 286 0.037
mitotic centrosome separation GO:0007100 4 0.037
negative regulation of immune system process GO:0002683 209 0.037
neural tube formation GO:0001841 108 0.036
positive regulation of cell death GO:0010942 224 0.036
male sex differentiation GO:0046661 109 0.035
regulation of chromosome organization GO:0033044 83 0.035
cellular amine metabolic process GO:0044106 44 0.035
nucleobase containing compound transport GO:0015931 27 0.035
histone h4 k20 trimethylation GO:0034773 2 0.035
protein ubiquitination GO:0016567 171 0.035
cellular carbohydrate catabolic process GO:0044275 15 0.034
regulation of organelle organization GO:0033043 289 0.034
negative regulation of apoptotic signaling pathway GO:2001234 104 0.034
oogenesis GO:0048477 56 0.034
carboxylic acid biosynthetic process GO:0046394 86 0.033
internal peptidyl lysine acetylation GO:0018393 42 0.033
protein methylation GO:0006479 81 0.033
negative regulation of mrna metabolic process GO:1903312 13 0.033
nuclear export GO:0051168 34 0.032
chromatin modification GO:0016568 187 0.032
negative regulation of atpase activity GO:0032780 2 0.032
striated muscle tissue development GO:0014706 293 0.032
protein alkylation GO:0008213 81 0.032
regulation of cell cycle GO:0051726 281 0.032
spindle organization GO:0007051 28 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
stem cell maintenance GO:0019827 130 0.031
positive regulation of protein phosphorylation GO:0001934 242 0.031
negative regulation of gene expression epigenetic GO:0045814 15 0.030
organelle fission GO:0048285 170 0.030
skin development GO:0043588 220 0.030
oocyte anterior posterior axis specification GO:0007314 2 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.029
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.029
myeloid cell differentiation GO:0030099 233 0.029
regulation of b cell activation GO:0050864 81 0.029
apoptotic signaling pathway GO:0097190 306 0.029
regulation of proteolysis GO:0030162 164 0.029
alternative mrna splicing via spliceosome GO:0000380 12 0.029
histone modification GO:0016570 159 0.028
centrosome organization GO:0051297 26 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
regulation of microtubule cytoskeleton organization GO:0070507 37 0.028
response to molecule of bacterial origin GO:0002237 143 0.028
inflammatory response GO:0006954 244 0.027
stem cell development GO:0048864 219 0.027
compound eye development GO:0048749 1 0.027
intracellular mrna localization GO:0008298 4 0.027
positive regulation of proteolysis GO:0045862 85 0.027
regulation of translation GO:0006417 71 0.027
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.026
sensory perception GO:0007600 245 0.026
ear development GO:0043583 200 0.026
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.026
positive regulation of transferase activity GO:0051347 167 0.025
skeletal myofibril assembly GO:0014866 4 0.025
protein localization to organelle GO:0033365 185 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
nitrogen compound transport GO:0071705 271 0.025
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 14 0.024
cellular response to steroid hormone stimulus GO:0071383 33 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
heterocycle catabolic process GO:0046700 280 0.024
amine metabolic process GO:0009308 45 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
glycogen catabolic process GO:0005980 5 0.024
negative regulation of nucleoside metabolic process GO:0045978 11 0.024
negative regulation of translation GO:0017148 22 0.024
regulation of homeostatic process GO:0032844 182 0.023
female gamete generation GO:0007292 74 0.023
endocytosis GO:0006897 168 0.023
regulation of nucleotide metabolic process GO:0006140 169 0.023
poly a mrna export from nucleus GO:0016973 4 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
regulation of generation of precursor metabolites and energy GO:0043467 38 0.023
negative regulation of mrna splicing via spliceosome GO:0048025 12 0.022
histone acetylation GO:0016573 41 0.022
placenta development GO:0001890 140 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.022
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.022
oocyte axis specification GO:0007309 2 0.022
rna catabolic process GO:0006401 29 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
ubiquitin dependent protein catabolic process GO:0006511 129 0.022
nuclear transcribed mrna catabolic process GO:0000956 16 0.021
mitotic nuclear division GO:0007067 48 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
transmembrane transport GO:0055085 412 0.021
regulation of embryonic development GO:0045995 71 0.021
establishment of rna localization GO:0051236 18 0.021
negative regulation of nucleotide catabolic process GO:0030812 9 0.021
positive regulation of cytoskeleton organization GO:0051495 49 0.020
male gonad development GO:0008584 88 0.020
negative regulation of dna templated transcription termination GO:0060567 1 0.020
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.020
mitotic cell cycle GO:0000278 195 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
epithelial cell proliferation GO:0050673 174 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
spermatid nucleus differentiation GO:0007289 19 0.020
carbohydrate catabolic process GO:0016052 32 0.020
histone h3 k9 dimethylation GO:0036123 4 0.019
regulation of hydrolase activity GO:0051336 246 0.019
muscle contraction GO:0006936 101 0.019
negative regulation of chromosome organization GO:2001251 30 0.019
nucleotide metabolic process GO:0009117 332 0.019
response to interleukin 4 GO:0070670 23 0.019
internal protein amino acid acetylation GO:0006475 42 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
negative regulation of organelle organization GO:0010639 90 0.019
epidermis development GO:0008544 187 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.018
ras protein signal transduction GO:0007265 77 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.018
nucleus organization GO:0006997 45 0.018
skeletal muscle fiber development GO:0048741 58 0.018
muscle cell differentiation GO:0042692 261 0.018
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 22 0.018
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.018
chromatin assembly GO:0031497 13 0.018
purine nucleotide catabolic process GO:0006195 211 0.017
microtubule organizing center organization GO:0031023 28 0.017
positive regulation of kinase activity GO:0033674 155 0.017
monocarboxylic acid biosynthetic process GO:0072330 61 0.017
wound healing GO:0042060 157 0.017
cell adhesion GO:0007155 329 0.017
blood circulation GO:0008015 195 0.017
homeostasis of number of cells GO:0048872 210 0.017
muscle system process GO:0003012 141 0.017
dna methylation involved in gamete generation GO:0043046 15 0.017
protein catabolic process GO:0030163 221 0.016
body morphogenesis GO:0010171 45 0.016
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.016
development of primary male sexual characteristics GO:0046546 88 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
response to nutrient levels GO:0031667 109 0.016
mesenchyme development GO:0060485 152 0.016
response to oxidative stress GO:0006979 123 0.016
muscle tissue development GO:0060537 308 0.016
nuclear division GO:0000280 158 0.016
regulation of anatomical structure size GO:0090066 178 0.016
regulation of tube size GO:0035150 57 0.016
protein dna complex subunit organization GO:0071824 28 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
chronological cell aging GO:0001300 1 0.015
cation transmembrane transport GO:0098655 266 0.015
histone methylation GO:0016571 71 0.015
mitotic cell cycle process GO:1903047 159 0.015
mrna stabilization GO:0048255 9 0.015
response to estrogen GO:0043627 24 0.015
segmentation GO:0035282 93 0.015
cytoplasmic transport GO:0016482 234 0.015
response to temperature stimulus GO:0009266 55 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
chemotaxis GO:0006935 247 0.015
fatty acid biosynthetic process GO:0006633 41 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
lateral inhibition GO:0046331 1 0.014
regulation of body fluid levels GO:0050878 162 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
polysaccharide biosynthetic process GO:0000271 20 0.014
regulation of blood pressure GO:0008217 93 0.014
skeletal muscle organ development GO:0060538 163 0.014
regulation of cell cycle phase transition GO:1901987 77 0.014
cellular response to estrogen stimulus GO:0071391 12 0.014
cell type specific apoptotic process GO:0097285 268 0.014
pole plasm assembly GO:0007315 2 0.014
regulation of rna stability GO:0043487 26 0.014
cellular protein catabolic process GO:0044257 155 0.014
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.014
nuclear transport GO:0051169 139 0.014
regulation of membrane potential GO:0042391 192 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
protein secretion GO:0009306 111 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
peptidyl amino acid modification GO:0018193 336 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
regulation of peptidase activity GO:0052547 96 0.013
regulation of inflammatory response GO:0050727 147 0.013
peptidyl lysine acetylation GO:0018394 45 0.013
dna hypermethylation GO:0044026 3 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
rna dependent dna replication GO:0006278 3 0.013
cell division GO:0051301 120 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
regulation of erythrocyte differentiation GO:0045646 23 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.013
regulation of dna binding GO:0051101 39 0.013
regulation of cell cycle process GO:0010564 160 0.013
positive regulation of secretion by cell GO:1903532 114 0.012
stem cell differentiation GO:0048863 268 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
response to acid chemical GO:0001101 111 0.012
female gonad development GO:0008585 71 0.012
regulation of multi organism process GO:0043900 111 0.012
production of mirnas involved in gene silencing by mirna GO:0035196 6 0.012
cellular homeostasis GO:0019725 240 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
tube formation GO:0035148 140 0.012
neural tube development GO:0021915 160 0.012
blood vessel morphogenesis GO:0048514 285 0.012
intracellular protein transport GO:0006886 204 0.012
cellular lipid metabolic process GO:0044255 323 0.012
protein acylation GO:0043543 64 0.012
response to radiation GO:0009314 165 0.012
regulation of circadian rhythm GO:0042752 58 0.012
heart morphogenesis GO:0003007 178 0.012
ion transmembrane transport GO:0034220 361 0.012
response to uv GO:0009411 44 0.012
interspecies interaction between organisms GO:0044419 83 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
nucleosome positioning GO:0016584 4 0.012
negative regulation of neuron differentiation GO:0045665 101 0.011
peptidyl lysine modification GO:0018205 77 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
cation transport GO:0006812 399 0.011
regulation of cellular amino acid metabolic process GO:0006521 5 0.011
phagocytosis GO:0006909 66 0.011
positive regulation of nervous system development GO:0051962 221 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
digestive tract development GO:0048565 190 0.011
regulation of nuclear division GO:0051783 56 0.011
response to inorganic substance GO:0010035 96 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
locomotory behavior GO:0007626 195 0.011
glycogen biosynthetic process GO:0005978 14 0.011
development of primary female sexual characteristics GO:0046545 73 0.011
positive regulation of dna binding GO:0043388 14 0.011
response to amino acid GO:0043200 37 0.010
nucleotide catabolic process GO:0009166 217 0.010
regulation of mapk cascade GO:0043408 248 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
meiotic cell cycle GO:0051321 122 0.010
er nucleus signaling pathway GO:0006984 27 0.010
positive regulation of growth GO:0045927 104 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
adult locomotory behavior GO:0008344 91 0.010
activation of cysteine type endopeptidase activity GO:0097202 27 0.010
intracellular receptor signaling pathway GO:0030522 74 0.010
response to light stimulus GO:0009416 135 0.010

Ptma disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010