Mus musculus

116 known processes

Ptpn1

protein tyrosine phosphatase, non-receptor type 1

(Aliases: PTP1B,PTP-1B,PTP-HA2)

Ptpn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peptidyl amino acid modification GO:0018193 336 0.285
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.240
Mouse
actin cytoskeleton organization GO:0030036 220 0.239
Human
small gtpase mediated signal transduction GO:0007264 97 0.199
cellular amine metabolic process GO:0044106 44 0.198
cellular amino acid metabolic process GO:0006520 103 0.181
response to organonitrogen compound GO:0010243 246 0.174
purine ribonucleotide metabolic process GO:0009150 290 0.171
ras protein signal transduction GO:0007265 77 0.169
ribonucleoside metabolic process GO:0009119 245 0.155
mapk cascade GO:0000165 281 0.154
regulation of cellular amino acid metabolic process GO:0006521 5 0.153
regulation of cellular amine metabolic process GO:0033238 20 0.147
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.143
amine metabolic process GO:0009308 45 0.131
purine nucleotide catabolic process GO:0006195 211 0.131
regulation of myeloid cell differentiation GO:0045637 96 0.131
Mouse
nucleoside metabolic process GO:0009116 246 0.115
negative regulation of protein phosphorylation GO:0001933 126 0.108
leukocyte differentiation GO:0002521 342 0.107
Mouse
immune effector process GO:0002252 321 0.107
lymphocyte mediated immunity GO:0002449 139 0.105
chromatin organization GO:0006325 206 0.103
positive regulation of cellular amine metabolic process GO:0033240 5 0.101
negative regulation of immune system process GO:0002683 209 0.093
Mouse
purine nucleotide metabolic process GO:0006163 302 0.090
sensory organ morphogenesis GO:0090596 242 0.087
endocytosis GO:0006897 168 0.085
Human
g protein coupled receptor signaling pathway GO:0007186 243 0.083
leukocyte mediated immunity GO:0002443 174 0.082
ribonucleoside catabolic process GO:0042454 206 0.080
regulation of transferase activity GO:0051338 263 0.080
cellular lipid metabolic process GO:0044255 323 0.080
post embryonic retina morphogenesis in camera type eye GO:0060060 3 0.079
camera type eye development GO:0043010 266 0.079
nucleotide metabolic process GO:0009117 332 0.078
glycosyl compound metabolic process GO:1901657 246 0.078
myeloid cell differentiation GO:0030099 233 0.077
Mouse
ribonucleotide catabolic process GO:0009261 208 0.076
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.075
carbohydrate derivative catabolic process GO:1901136 231 0.075
purine ribonucleoside metabolic process GO:0046128 241 0.075
purine containing compound catabolic process GO:0072523 213 0.073
nucleoside triphosphate catabolic process GO:0009143 205 0.072
regulation of kinase activity GO:0043549 249 0.072
ribose phosphate metabolic process GO:0019693 291 0.072
positive regulation of protein phosphorylation GO:0001934 242 0.069
aromatic compound catabolic process GO:0019439 286 0.068
purine containing compound metabolic process GO:0072521 311 0.068
nucleoside catabolic process GO:0009164 206 0.068
glycosyl compound catabolic process GO:1901658 206 0.067
ribonucleotide metabolic process GO:0009259 291 0.067
cellular response to lipopolysaccharide GO:0071222 77 0.067
positive regulation of protein modification process GO:0031401 299 0.067
actin filament organization GO:0007015 113 0.065
cellular response to peptide GO:1901653 92 0.065
nucleoside triphosphate metabolic process GO:0009141 230 0.063
purine ribonucleoside catabolic process GO:0046130 205 0.063
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.062
Mouse
protein autophosphorylation GO:0046777 61 0.062
actin polymerization or depolymerization GO:0008154 54 0.062
nuclear transport GO:0051169 139 0.061
t cell differentiation GO:0030217 174 0.061
Mouse
chromatin modification GO:0016568 187 0.061
retina development in camera type eye GO:0060041 119 0.061
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.060
purine nucleoside triphosphate metabolic process GO:0009144 226 0.060
photoreceptor cell morphogenesis GO:0008594 3 0.060
adaptive immune response GO:0002250 155 0.059
purine nucleoside catabolic process GO:0006152 205 0.059
positive regulation of apoptotic signaling pathway GO:2001235 95 0.059
negative regulation of phosphorylation GO:0042326 166 0.057
cell activation involved in immune response GO:0002263 126 0.056
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.055
response to light stimulus GO:0009416 135 0.055
heterocycle catabolic process GO:0046700 280 0.055
mitotic cell cycle GO:0000278 195 0.054
meiotic cell cycle GO:0051321 122 0.053
response to organic cyclic compound GO:0014070 198 0.053
cd4 positive alpha beta t cell activation GO:0035710 45 0.053
positive regulation of organelle organization GO:0010638 128 0.052
positive regulation of cell development GO:0010720 237 0.051
negative regulation of molecular function GO:0044092 258 0.051
regulation of protein kinase activity GO:0045859 232 0.051
regulation of cell adhesion GO:0030155 154 0.051
gtp catabolic process GO:0006184 143 0.051
transmembrane transport GO:0055085 412 0.051
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.050
cellular response to organonitrogen compound GO:0071417 145 0.049
positive regulation of nucleoside metabolic process GO:0045979 91 0.049
cytokine production GO:0001816 319 0.047
alpha beta t cell activation involved in immune response GO:0002287 31 0.047
negative regulation of protein maturation GO:1903318 79 0.047
nucleoside phosphate metabolic process GO:0006753 338 0.047
organonitrogen compound catabolic process GO:1901565 264 0.046
cellular response to hormone stimulus GO:0032870 150 0.046
intracellular protein transport GO:0006886 204 0.045
multicellular organism growth GO:0035264 161 0.045
cytoplasmic transport GO:0016482 234 0.045
lymphocyte activation involved in immune response GO:0002285 93 0.045
photoreceptor cell differentiation GO:0046530 52 0.044
regulation of proteolysis GO:0030162 164 0.044
protein maturation GO:0051604 176 0.044
regulation of apoptotic signaling pathway GO:2001233 197 0.044
negative regulation of cellular amine metabolic process GO:0033239 1 0.044
regulation of vesicle mediated transport GO:0060627 139 0.044
Human
regulation of leukocyte differentiation GO:1902105 159 0.043
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.043
protein processing GO:0016485 163 0.043
cellular response to cytokine stimulus GO:0071345 189 0.043
Mouse
establishment of protein localization to organelle GO:0072594 118 0.043
cellular response to molecule of bacterial origin GO:0071219 83 0.043
regulation of endocytosis GO:0030100 69 0.042
Human
response to lipopolysaccharide GO:0032496 128 0.042
regulation of membrane potential GO:0042391 192 0.041
forebrain development GO:0030900 302 0.041
regulation of intracellular transport GO:0032386 159 0.041
regulation of cytokine production GO:0001817 266 0.041
alpha beta t cell activation GO:0046631 91 0.041
regulation of t cell differentiation GO:0045580 83 0.041
Mouse
response to interleukin 12 GO:0070671 2 0.040
nucleocytoplasmic transport GO:0006913 139 0.040
cellular ketone metabolic process GO:0042180 84 0.040
Mouse
organophosphate catabolic process GO:0046434 232 0.040
regulation of cytoplasmic transport GO:1903649 112 0.039
positive regulation of nucleotide metabolic process GO:0045981 114 0.039
histone acetylation GO:0016573 41 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
organelle fission GO:0048285 170 0.038
regulation of ras gtpase activity GO:0032318 88 0.038
cellular chemical homeostasis GO:0055082 215 0.038
adult behavior GO:0030534 135 0.038
phagocytosis GO:0006909 66 0.037
alpha beta t cell differentiation GO:0046632 69 0.037
gland development GO:0048732 330 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
cell adhesion GO:0007155 329 0.037
rho protein signal transduction GO:0007266 32 0.037
regulation of purine nucleotide metabolic process GO:1900542 169 0.037
regulation of cell migration GO:0030334 219 0.037
negative regulation of intracellular signal transduction GO:1902532 167 0.036
regulation of cellular response to stress GO:0080135 159 0.036
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.036
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.036
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.036
regulation of cell activation GO:0050865 289 0.036
Mouse
calcium ion transport GO:0006816 159 0.035
response to radiation GO:0009314 165 0.035
fat cell differentiation GO:0045444 160 0.035
leukocyte activation involved in immune response GO:0002366 126 0.035
modification dependent macromolecule catabolic process GO:0043632 133 0.035
inflammatory response GO:0006954 244 0.035
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.035
nitrogen compound transport GO:0071705 271 0.034
carbohydrate derivative biosynthetic process GO:1901137 183 0.034
regulation of hydrolase activity GO:0051336 246 0.034
positive regulation of nervous system development GO:0051962 221 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.034
regulation of ras protein signal transduction GO:0046578 114 0.033
positive regulation of growth GO:0045927 104 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
lymphocyte differentiation GO:0030098 242 0.033
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.033
mitotic cytokinesis GO:0000281 4 0.033
protein modification by small protein conjugation GO:0032446 187 0.033
proteasomal protein catabolic process GO:0010498 98 0.033
development of primary sexual characteristics GO:0045137 143 0.033
heart process GO:0003015 94 0.033
myeloid leukocyte differentiation GO:0002573 119 0.033
Mouse
regulation of heart contraction GO:0008016 77 0.033
positive regulation of defense response GO:0031349 124 0.032
cation transport GO:0006812 399 0.032
cellular response to biotic stimulus GO:0071216 92 0.032
cellular response to peptide hormone stimulus GO:0071375 92 0.032
regulation of cellular component size GO:0032535 121 0.032
regulation of cell motility GO:2000145 236 0.031
activation of janus kinase activity GO:0042976 2 0.031
regulation of nucleotide metabolic process GO:0006140 169 0.031
stem cell differentiation GO:0048863 268 0.031
positive regulation of protein kinase activity GO:0045860 144 0.031
negative regulation of peptidase activity GO:0010466 46 0.031
protein targeting GO:0006605 143 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.031
regulation of reactive oxygen species metabolic process GO:2000377 40 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
leukocyte migration GO:0050900 124 0.031
response to oxidative stress GO:0006979 123 0.030
dephosphorylation GO:0016311 129 0.030
organophosphate biosynthetic process GO:0090407 122 0.030
skin development GO:0043588 220 0.030
toll like receptor signaling pathway GO:0002224 38 0.029
cellular protein complex assembly GO:0043623 116 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
cellular response to lipid GO:0071396 145 0.029
nucleotide catabolic process GO:0009166 217 0.029
regulation of neuron projection development GO:0010975 169 0.029
negative regulation of cell proliferation GO:0008285 296 0.029
cellular homeostasis GO:0019725 240 0.029
mrna metabolic process GO:0016071 84 0.029
regulation of myeloid leukocyte differentiation GO:0002761 58 0.029
Mouse
positive regulation of transferase activity GO:0051347 167 0.029
response to growth factor GO:0070848 198 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.029
digestive tract development GO:0048565 190 0.029
regulation of organelle organization GO:0033043 289 0.028
cytokine mediated signaling pathway GO:0019221 115 0.028
Mouse
macromolecule methylation GO:0043414 120 0.028
blood circulation GO:0008015 195 0.028
ion transmembrane transport GO:0034220 361 0.028
defense response to other organism GO:0098542 197 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
negative regulation of leukocyte differentiation GO:1902106 51 0.028
Mouse
response to amino acid GO:0043200 37 0.027
marginal zone b cell differentiation GO:0002315 2 0.027
epithelial cell morphogenesis GO:0003382 41 0.027
positive regulation of leukocyte differentiation GO:1902107 86 0.027
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
mitochondrion organization GO:0007005 134 0.027
positive regulation of mapk cascade GO:0043410 170 0.026
positive regulation of cell death GO:0010942 224 0.026
regulation of t cell activation GO:0050863 170 0.026
Mouse
t cell differentiation involved in immune response GO:0002292 30 0.026
intracellular receptor signaling pathway GO:0030522 74 0.026
photoreceptor cell development GO:0042461 40 0.026
regulation of antimicrobial humoral response GO:0002759 3 0.026
t cell activation GO:0042110 289 0.025
Mouse
cell growth GO:0016049 130 0.025
regulation of mapk cascade GO:0043408 248 0.025
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.025
regulation of osteoblast differentiation GO:0045667 67 0.025
ral protein signal transduction GO:0032484 2 0.025
regulation of jak stat cascade GO:0046425 34 0.025
Mouse
histone modification GO:0016570 159 0.025
innate immune response GO:0045087 157 0.025
Mouse
meiotic nuclear division GO:0007126 115 0.025
eye photoreceptor cell differentiation GO:0001754 41 0.025
lipid biosynthetic process GO:0008610 179 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
establishment or maintenance of cell polarity GO:0007163 86 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
cytokine biosynthetic process GO:0042089 68 0.025
positive regulation of gtp catabolic process GO:0033126 85 0.024
apical constriction GO:0003383 4 0.024
female sex differentiation GO:0046660 84 0.024
regulation of actin filament polymerization GO:0030833 38 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
regulation of ion transport GO:0043269 215 0.024
methylation GO:0032259 134 0.024
neuron death GO:0070997 154 0.024
cytokine metabolic process GO:0042107 71 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.023
stress activated mapk cascade GO:0051403 80 0.023
peptidyl serine phosphorylation GO:0018105 74 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.023
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.023
ear development GO:0043583 200 0.023
alcohol metabolic process GO:0006066 116 0.023
ameboidal type cell migration GO:0001667 128 0.023
cation homeostasis GO:0055080 212 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
response to extracellular stimulus GO:0009991 127 0.023
connective tissue development GO:0061448 179 0.023
gonad development GO:0008406 141 0.023
heart contraction GO:0060047 93 0.023
cell fate commitment GO:0045165 210 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
response to peptide GO:1901652 136 0.023
positive regulation of antimicrobial peptide production GO:0002225 1 0.023
transmission of nerve impulse GO:0019226 76 0.023
regulation of hormone levels GO:0010817 211 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
Mouse
actin filament polymerization GO:0030041 44 0.023
regulation of actin nucleation GO:0051125 4 0.023
myosin filament assembly GO:0031034 2 0.022
homeostasis of number of cells GO:0048872 210 0.022
Mouse
t helper cell differentiation GO:0042093 28 0.022
negative regulation of defense response GO:0031348 77 0.022
Mouse
activation of mapkkk activity GO:0000185 1 0.022
rhythmic process GO:0048511 174 0.022
positive regulation of ras gtpase activity GO:0032320 65 0.022
positive regulation of immune effector process GO:0002699 107 0.022
digestive system development GO:0055123 200 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.022
organelle localization GO:0051640 179 0.022
positive regulation of cytokine production GO:0001819 174 0.022
spermatogenesis GO:0007283 284 0.022
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.022
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
circulatory system process GO:0003013 197 0.022
positive regulation of neuron differentiation GO:0045666 141 0.022
protein localization to organelle GO:0033365 185 0.022
myeloid cell homeostasis GO:0002262 114 0.021
Mouse
ossification GO:0001503 216 0.021
nucleoside phosphate biosynthetic process GO:1901293 79 0.021
jak stat cascade GO:0007259 42 0.021
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.021
regulation of protein processing GO:0070613 96 0.021
nuclear division GO:0000280 158 0.021
locomotory behavior GO:0007626 195 0.021
protein localization to nucleus GO:0034504 121 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
wnt signaling pathway GO:0016055 188 0.021
positive regulation of kinase activity GO:0033674 155 0.021
dendrite development GO:0016358 115 0.021
gtp metabolic process GO:0046039 144 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
protein ubiquitination GO:0016567 171 0.021
cell division GO:0051301 120 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
positive regulation of lymphocyte activation GO:0051251 140 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
asymmetric neuroblast division GO:0055059 1 0.020
response to acid chemical GO:0001101 111 0.020
sensory system development GO:0048880 3 0.020
germ cell development GO:0007281 185 0.020
atp catabolic process GO:0006200 55 0.020
purine nucleotide biosynthetic process GO:0006164 65 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
negative regulation of apoptotic signaling pathway GO:2001234 104 0.020
cell type specific apoptotic process GO:0097285 268 0.020
lens development in camera type eye GO:0002088 62 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
regulation of anatomical structure size GO:0090066 178 0.020
compound eye development GO:0048749 1 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
immune response activating signal transduction GO:0002757 116 0.020
Mouse
response to inorganic substance GO:0010035 96 0.020
dna methylation GO:0006306 43 0.020
morphogenesis of a branching epithelium GO:0061138 193 0.020
b cell activation GO:0042113 161 0.020
Mouse
epithelial tube morphogenesis GO:0060562 303 0.020
regulation of innate immune response GO:0045088 91 0.020
Mouse
negative regulation of endopeptidase activity GO:0010951 44 0.020
regulation of lymphocyte differentiation GO:0045619 107 0.020
Mouse
atp metabolic process GO:0046034 75 0.020
sulfur compound metabolic process GO:0006790 100 0.020
positive regulation of immature t cell proliferation GO:0033091 4 0.019
asymmetric stem cell division GO:0098722 3 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.019
regulation of inflammatory response GO:0050727 147 0.019
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.019
response to alkaloid GO:0043279 34 0.019
regulation of peptidase activity GO:0052547 96 0.019
membrane organization GO:0061024 245 0.019
regulation of leukocyte mediated immunity GO:0002703 104 0.019
organelle assembly GO:0070925 177 0.019
spermatid differentiation GO:0048515 115 0.019
purine nucleoside monophosphate catabolic process GO:0009128 58 0.019
sensory perception GO:0007600 245 0.019
t cell homeostasis GO:0043029 35 0.019
fertilization GO:0009566 127 0.019
regulation of protein transport GO:0051223 163 0.019
receptor mediated endocytosis GO:0006898 51 0.019
pattern recognition receptor signaling pathway GO:0002221 47 0.019
guanosine containing compound metabolic process GO:1901068 144 0.019
lateral line system development GO:0048925 1 0.019
regulation of gtp catabolic process GO:0033124 113 0.019
maintenance of location GO:0051235 89 0.019
Mouse
peptidyl threonine phosphorylation GO:0018107 31 0.019
erythrocyte differentiation GO:0030218 88 0.018
Mouse
protein import GO:0017038 101 0.018
response to reactive oxygen species GO:0000302 56 0.018
response to hypoxia GO:0001666 58 0.018
organic hydroxy compound transport GO:0015850 93 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
digestive tract morphogenesis GO:0048546 147 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
Mouse
apoptotic signaling pathway GO:0097190 306 0.018
positive regulation of nucleotide catabolic process GO:0030813 88 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
cellular response to abiotic stimulus GO:0071214 56 0.018
natural killer cell proliferation GO:0001787 3 0.018
multicellular organismal signaling GO:0035637 91 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.018
regulation of blood circulation GO:1903522 93 0.018
actin mediated cell contraction GO:0070252 15 0.018
regulation of defense response GO:0031347 233 0.018
Mouse
response to insulin GO:0032868 100 0.018
regulation of alpha beta t cell activation GO:0046634 53 0.018
regulation of neuron differentiation GO:0045664 281 0.018
covalent chromatin modification GO:0016569 163 0.018
carbohydrate metabolic process GO:0005975 230 0.018
Mouse
regulation of fat cell differentiation GO:0045598 81 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.018
protein secretion GO:0009306 111 0.018
regulation of protein targeting GO:1903533 61 0.018
developmental maturation GO:0021700 193 0.017
neuronal action potential GO:0019228 54 0.017
negative regulation of growth GO:0045926 99 0.017
positive regulation of cytokine biosynthetic process GO:0042108 40 0.017
negative regulation of myeloid cell differentiation GO:0045638 38 0.017
Mouse
osteoclast differentiation GO:0030316 62 0.017
t cell activation involved in immune response GO:0002286 43 0.017
primary neural tube formation GO:0014020 95 0.017
cellularization GO:0007349 1 0.017
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.017
muscle cell differentiation GO:0042692 261 0.017
establishment of organelle localization GO:0051656 122 0.017
regulation of neuron death GO:1901214 134 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.017
rna processing GO:0006396 105 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
positive regulation of antimicrobial humoral response GO:0002760 2 0.017
response to peptide hormone GO:0043434 127 0.017
sequestering of calcium ion GO:0051208 18 0.017
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.017
regulation of cell projection organization GO:0031344 206 0.017
b cell mediated immunity GO:0019724 71 0.017
positive regulation of t cell activation GO:0050870 101 0.017
histone h4 k12 acetylation GO:0043983 2 0.017
epithelial cell development GO:0002064 159 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
action potential GO:0001508 78 0.017
regulation of rho gtpase activity GO:0032319 58 0.017
tyrosine phosphorylation of stat protein GO:0007260 23 0.017
Mouse
nucleotide biosynthetic process GO:0009165 78 0.017
regulation of chromatin modification GO:1903308 57 0.017
adult locomotory behavior GO:0008344 91 0.017
positive regulation of gtpase activity GO:0043547 85 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
Mouse
regulation of insulin receptor signaling pathway GO:0046626 21 0.016
Mouse Rat
regulation of ossification GO:0030278 112 0.016
protein localization to membrane GO:0072657 108 0.016
metal ion homeostasis GO:0055065 189 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
negative regulation of neuron death GO:1901215 98 0.016
male gamete generation GO:0048232 285 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
negative regulation of protein modification process GO:0031400 163 0.016
cell killing GO:0001906 67 0.016
glial cell differentiation GO:0010001 131 0.016
divalent inorganic cation transport GO:0072511 178 0.016
exocytosis GO:0006887 121 0.016
cardiac muscle tissue development GO:0048738 130 0.016
regulation of production of molecular mediator of immune response GO:0002700 65 0.016
hormone secretion GO:0046879 128 0.016
regulation of secretion GO:0051046 274 0.016
negative regulation of proteolysis GO:0045861 74 0.016
t cell proliferation GO:0042098 120 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
regulation of protein maturation GO:1903317 96 0.016
liver development GO:0001889 66 0.015
carbohydrate homeostasis GO:0033500 128 0.015
Mouse
meiotic cell cycle process GO:1903046 77 0.015
cellular amide metabolic process GO:0043603 58 0.015
development of primary female sexual characteristics GO:0046545 73 0.015
negative regulation of phagocytosis GO:0050765 4 0.015
lymphocyte apoptotic process GO:0070227 54 0.015
peptide transport GO:0015833 133 0.015
respiratory tube development GO:0030323 167 0.015
regulation of metal ion transport GO:0010959 106 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
response to nutrient levels GO:0031667 109 0.015
circadian regulation of gene expression GO:0032922 48 0.015
blood vessel morphogenesis GO:0048514 285 0.015
cation transmembrane transport GO:0098655 266 0.015
regulation of actin filament length GO:0030832 45 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
positive regulation of alpha beta t cell activation GO:0046635 39 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
sensory perception of umami taste GO:0050917 4 0.015
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.015
myotube differentiation GO:0014902 105 0.015
sequestering of metal ion GO:0051238 19 0.015
dna repair GO:0006281 107 0.015
monosaccharide metabolic process GO:0005996 106 0.015
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.015
nuclear import GO:0051170 95 0.015
positive regulation of actin nucleation GO:0051127 3 0.015
regulation of body fluid levels GO:0050878 162 0.015
regulation of antimicrobial peptide production GO:0002784 1 0.015
regulation of secretion by cell GO:1903530 249 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
leukocyte proliferation GO:0070661 172 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
cartilage development GO:0051216 140 0.015
gliogenesis GO:0042063 141 0.015
negative regulation of mapk cascade GO:0043409 65 0.015

Ptpn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.061
disease of anatomical entity DOID:7 0 0.061
disease of cellular proliferation DOID:14566 0 0.047
cancer DOID:162 0 0.047
immune system cancer DOID:0060083 0 0.032
organ system cancer DOID:0050686 0 0.032
hematologic cancer DOID:2531 0 0.032
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.019