Mus musculus

23 known processes

Ptprb

protein tyrosine phosphatase, receptor type, B

(Aliases: Rptpb,VE-PTP,Veptp,Ptpz,3230402H02Rik,C130094E24)

Ptprb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of vasculogenesis GO:2001212 9 0.937
heart trabecula formation GO:0060347 14 0.932
tissue migration GO:0090130 68 0.906
cell adhesion GO:0007155 329 0.863
Mouse
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.843
smooth muscle cell chemotaxis GO:0071670 2 0.841
kidney development GO:0001822 213 0.839
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.838
regulation of cellular amine metabolic process GO:0033238 20 0.829
blood vessel morphogenesis GO:0048514 285 0.809
epithelium migration GO:0090132 63 0.803
regulation of cellular amino acid metabolic process GO:0006521 5 0.799
cell migration involved in coronary angiogenesis GO:0060981 1 0.794
retina vasculature development in camera type eye GO:0061298 17 0.794
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.760
ameboidal type cell migration GO:0001667 128 0.758
peptidyl tyrosine modification GO:0018212 145 0.752
glomerulus development GO:0032835 40 0.750
Mouse
camera type eye development GO:0043010 266 0.742
axonogenesis GO:0007409 274 0.736
Mouse Fly
cellular response to growth factor stimulus GO:0071363 197 0.723
single organism cell adhesion GO:0098602 156 0.720
cell substrate adhesion GO:0031589 130 0.715
Mouse
regulation of transferase activity GO:0051338 263 0.714
Mouse
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.710
regulation of cell projection organization GO:0031344 206 0.708
epithelial cell migration GO:0010631 63 0.705
cellular response to erythropoietin GO:0036018 1 0.704
cardiocyte differentiation GO:0035051 87 0.696
ion transmembrane transport GO:0034220 361 0.683
single organismal cell cell adhesion GO:0016337 131 0.681
regulation of epithelial cell migration GO:0010632 35 0.678
positive regulation of cellular amine metabolic process GO:0033240 5 0.673
kit signaling pathway GO:0038109 3 0.663
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.653
angiogenesis GO:0001525 201 0.638
heart contraction GO:0060047 93 0.634
neuroepithelial cell differentiation GO:0060563 37 0.630
embryonic organ morphogenesis GO:0048562 276 0.629
Mouse
wound healing GO:0042060 157 0.620
Mouse
regulation of muscle system process GO:0090257 80 0.613
cellular amine metabolic process GO:0044106 44 0.610
muscle system process GO:0003012 141 0.604
g protein coupled receptor signaling pathway GO:0007186 243 0.601
positive regulation of cell migration GO:0030335 109 0.598
Mouse
urogenital system development GO:0001655 261 0.597
Mouse
nephron development GO:0072006 109 0.597
Mouse
regulation of endothelial cell migration GO:0010594 22 0.596
positive regulation of protein phosphorylation GO:0001934 242 0.587
branching involved in salivary gland morphogenesis GO:0060445 26 0.580
regulation of epithelial cell proliferation GO:0050678 141 0.579
regulation of lens epithelial cell proliferation GO:2001109 1 0.573
negative regulation of cell proliferation GO:0008285 296 0.573
Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.563
melanocyte migration GO:0097324 2 0.548
kidney vasculature development GO:0061440 15 0.548
developmental maturation GO:0021700 193 0.547
transmembrane transport GO:0055085 412 0.544
metanephric mesenchymal cell migration GO:0035789 2 0.541
mapk cascade GO:0000165 281 0.539
Mouse
negative regulation of endothelial cell migration GO:0010596 4 0.538
response to erythropoietin GO:0036017 1 0.537
regulation of kinase activity GO:0043549 249 0.532
Mouse
cellular amino acid metabolic process GO:0006520 103 0.530
neuron projection guidance GO:0097485 141 0.513
Mouse Fly
regulation of body fluid levels GO:0050878 162 0.512
Mouse
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.512
amine metabolic process GO:0009308 45 0.511
organonitrogen compound catabolic process GO:1901565 264 0.508
erythropoietin mediated signaling pathway GO:0038162 1 0.504
smooth muscle cell migration GO:0014909 10 0.504
cellular ketone metabolic process GO:0042180 84 0.493
regulation of heart contraction GO:0008016 77 0.490
muscle tissue development GO:0060537 308 0.490
lung development GO:0030324 164 0.487
positive regulation of cell substrate adhesion GO:0010811 47 0.484
Mouse
vasodilation GO:0042311 28 0.483
heart morphogenesis GO:0003007 178 0.481
gland development GO:0048732 330 0.480
metanephric glomerular mesangium development GO:0072223 3 0.466
cell type specific apoptotic process GO:0097285 268 0.456
positive regulation of mapk cascade GO:0043410 170 0.453
cell matrix adhesion GO:0007160 68 0.450
Mouse
positive regulation of smooth muscle cell migration GO:0014911 4 0.447
pro t cell differentiation GO:0002572 3 0.447
positive regulation of bmp signaling pathway GO:0030513 23 0.443
diencephalon development GO:0021536 63 0.441
chemotaxis GO:0006935 247 0.436
Mouse Fly
regulation of mapk cascade GO:0043408 248 0.432
Mouse
muscle adaptation GO:0043500 39 0.430
renal vesicle induction GO:0072034 3 0.425
inositol lipid mediated signaling GO:0048017 41 0.425
immune effector process GO:0002252 321 0.421
nucleoside phosphate metabolic process GO:0006753 338 0.420
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.416
Mouse
kidney epithelium development GO:0072073 121 0.408
Mouse
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.406
endothelial cell migration GO:0043542 44 0.404
regulation of angiogenesis GO:0045765 81 0.404
regulation of mesenchymal cell proliferation GO:0010464 37 0.403
vascular process in circulatory system GO:0003018 62 0.402
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.400
cell migration involved in vasculogenesis GO:0035441 2 0.399
regulation of secretion GO:0051046 274 0.393
mesenchymal cell proliferation GO:0010463 44 0.393
regulation of blood vessel remodeling GO:0060312 3 0.390
extracellular matrix organization GO:0030198 147 0.385
stem cell differentiation GO:0048863 268 0.385
positive regulation of endothelial cell proliferation GO:0001938 17 0.383
regulation of cellular ketone metabolic process GO:0010565 66 0.377
retina development in camera type eye GO:0060041 119 0.376
synaptic transmission GO:0007268 329 0.372
cell fate commitment GO:0045165 210 0.371
regulation of cell migration GO:0030334 219 0.369
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.367
regulation of hippo signaling GO:0035330 1 0.363
cytokine mediated signaling pathway GO:0019221 115 0.361
endocardium development GO:0003157 10 0.358
positive regulation of cellular component biogenesis GO:0044089 94 0.356
digestive system development GO:0055123 200 0.355
positive regulation of vasculogenesis GO:2001214 7 0.355
positive regulation of cell development GO:0010720 237 0.353
trunk neural crest cell migration GO:0036484 4 0.347
endothelial cell differentiation GO:0045446 41 0.347
dendritic cell cytokine production GO:0002371 3 0.346
morphogenesis of a branching structure GO:0001763 203 0.346
forebrain development GO:0030900 302 0.341
stem cell proliferation GO:0072089 117 0.341
axon guidance GO:0007411 141 0.340
Mouse Fly
cell cell adhesion GO:0098609 41 0.334
regulation of bmp signaling pathway GO:0030510 60 0.333
endodermal cell fate determination GO:0007493 2 0.333
positive regulation of protein modification process GO:0031401 299 0.332
peptidyl amino acid modification GO:0018193 336 0.330
artery development GO:0060840 53 0.328
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.326
regulation of system process GO:0044057 200 0.326
Mouse
cardiac atrium development GO:0003230 24 0.326
myeloid cell differentiation GO:0030099 233 0.324
ribonucleotide metabolic process GO:0009259 291 0.319
regulation of cell motility GO:2000145 236 0.319
Mouse
positive regulation of nervous system development GO:0051962 221 0.318
embryonic skeletal system morphogenesis GO:0048704 91 0.314
vegf activated neuropilin signaling pathway GO:0038190 2 0.311
cardiac chamber development GO:0003205 108 0.310
cation transport GO:0006812 399 0.308
cardiac muscle cell development GO:0055013 39 0.307
lymphocyte differentiation GO:0030098 242 0.307
lymph vessel morphogenesis GO:0036303 11 0.305
cardiac cell fate specification GO:0060912 2 0.304
regulation of ion transport GO:0043269 215 0.302
cell substrate junction assembly GO:0007044 24 0.301
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.299
positive regulation of neuron differentiation GO:0045666 141 0.298
septum primum development GO:0003284 4 0.294
heart trabecula morphogenesis GO:0061384 26 0.292
epithelial cell proliferation GO:0050673 174 0.292
cardiac cell development GO:0055006 41 0.291
cellular response to thyroid hormone stimulus GO:0097067 1 0.289
hematopoietic progenitor cell differentiation GO:0002244 143 0.289
Mouse
limb development GO:0060173 166 0.288
muscle cell differentiation GO:0042692 261 0.285
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.283
glial cell differentiation GO:0010001 131 0.277
Mouse
stem cell development GO:0048864 219 0.276
metanephric glomerulus morphogenesis GO:0072275 3 0.275
response to organonitrogen compound GO:0010243 246 0.275
regulation of neuron projection development GO:0010975 169 0.274
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.271
positive regulation of ras gtpase activity GO:0032320 65 0.268
positive regulation of chemotaxis GO:0050921 38 0.268
Mouse
regulation of hydrolase activity GO:0051336 246 0.267
sensory perception of mechanical stimulus GO:0050954 107 0.267
Mouse
cell maturation GO:0048469 127 0.264
membrane organization GO:0061024 245 0.262
regulation of ion transmembrane transport GO:0034765 119 0.258
inorganic cation transmembrane transport GO:0098662 207 0.258
cytokine production involved in immune response GO:0002367 34 0.257
male sex differentiation GO:0046661 109 0.255
negative regulation of sodium ion transmembrane transport GO:1902306 1 0.254
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.254
endothelial cell apoptotic process GO:0072577 9 0.253
morphogenesis of a branching epithelium GO:0061138 193 0.253
central nervous system neuron differentiation GO:0021953 162 0.252
regulation of anatomical structure size GO:0090066 178 0.246
negative regulation of epithelial cell proliferation GO:0050680 64 0.246
positive regulation of protein kinase activity GO:0045860 144 0.243
regulation of positive chemotaxis GO:0050926 7 0.241
developmental programmed cell death GO:0010623 41 0.239
cellular homeostasis GO:0019725 240 0.238
lung alveolus development GO:0048286 45 0.236
mast cell differentiation GO:0060374 5 0.236
regulation of cell adhesion GO:0030155 154 0.234
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.234
av node cell to bundle of his cell communication GO:0086067 2 0.233
extracellular structure organization GO:0043062 148 0.230
cardiac chamber morphogenesis GO:0003206 93 0.230
peptidyl tyrosine phosphorylation GO:0018108 143 0.229
neuron migration GO:0001764 122 0.228
sympathetic neuron projection extension GO:0097490 4 0.228
digestive tract morphogenesis GO:0048546 147 0.228
connective tissue development GO:0061448 179 0.225
regulation of cellular response to growth factor stimulus GO:0090287 82 0.223
t cell activation GO:0042110 289 0.222
regulation of smooth muscle cell migration GO:0014910 6 0.221
cation homeostasis GO:0055080 212 0.220
epithelial cell differentiation involved in kidney development GO:0035850 23 0.220
Mouse
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.220
chemical homeostasis within a tissue GO:0048875 9 0.219
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.217
respiratory system development GO:0060541 190 0.216
Fly
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.213
regulation of secretion by cell GO:1903530 249 0.211
cellular response to stem cell factor stimulus GO:0036216 3 0.208
blood circulation GO:0008015 195 0.206
Mouse
sensory organ morphogenesis GO:0090596 242 0.206
Mouse
heart process GO:0003015 94 0.205
metanephric epithelium development GO:0072207 21 0.204
cellular component assembly involved in morphogenesis GO:0010927 139 0.204
regulation of axon guidance GO:1902667 13 0.202
renal system development GO:0072001 225 0.202
Mouse
skeletal muscle organ development GO:0060538 163 0.201
calcium ion transport GO:0006816 159 0.199
metanephric glomerular capillary formation GO:0072277 3 0.199
sensory perception GO:0007600 245 0.198
Mouse
retinal rod cell differentiation GO:0060221 2 0.197
synaptic transmission glutamatergic GO:0035249 36 0.195
positive regulation of ion transmembrane transport GO:0034767 24 0.195
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 14 0.194
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.194
positive regulation of growth GO:0045927 104 0.193
regulation of cell size GO:0008361 72 0.193
lung smooth muscle development GO:0061145 2 0.193
regulation of stem cell proliferation GO:0072091 78 0.192
purine containing compound metabolic process GO:0072521 311 0.192
mesendoderm development GO:0048382 3 0.191
positive regulation of epithelial cell migration GO:0010634 19 0.190
erythrocyte differentiation GO:0030218 88 0.187
regulation of organ morphogenesis GO:2000027 144 0.187
erk1 and erk2 cascade GO:0070371 77 0.186
cardiac muscle tissue development GO:0048738 130 0.186
embryonic heart tube development GO:0035050 65 0.185
cardiac muscle fiber development GO:0048739 4 0.185
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.185
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.184
telencephalon development GO:0021537 186 0.184
neural crest cell development GO:0014032 48 0.183
smooth muscle tissue development GO:0048745 22 0.181
positive regulation of angiogenesis GO:0045766 46 0.180
positive regulation of axon extension GO:0045773 20 0.179
skin development GO:0043588 220 0.175
Mouse
male gonad development GO:0008584 88 0.175
stem cell maintenance GO:0019827 130 0.173
negative regulation of cell development GO:0010721 169 0.173
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.172
cardiac muscle cell differentiation GO:0055007 69 0.172
cell migration involved in kidney development GO:0035787 3 0.171
morphogenesis of embryonic epithelium GO:0016331 159 0.170
multicellular organismal homeostasis GO:0048871 164 0.169
regulation of transmembrane transport GO:0034762 128 0.169
male gamete generation GO:0048232 285 0.169
regulation of ras gtpase activity GO:0032318 88 0.168
salivary gland morphogenesis GO:0007435 33 0.168
metanephric glomerulus development GO:0072224 13 0.165
regulation of peptidyl serine phosphorylation GO:0033135 39 0.165
phosphatidylinositol mediated signaling GO:0048015 41 0.164
organ growth GO:0035265 117 0.164
muscle contraction GO:0006936 101 0.164
regulation of reproductive process GO:2000241 66 0.163
regulation of cardiac muscle cell proliferation GO:0060043 23 0.162
striated muscle tissue development GO:0014706 293 0.162
cell junction organization GO:0034330 77 0.160
Mouse
liver development GO:0001889 66 0.159
positive regulation of neuron projection development GO:0010976 79 0.159
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.159
regulation of metanephros development GO:0072215 15 0.159
adherens junction assembly GO:0034333 22 0.158
neural tube formation GO:0001841 108 0.157
mesonephric tubule development GO:0072164 94 0.156
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.156
regulation of hormone levels GO:0010817 211 0.156
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.156
sphingolipid metabolic process GO:0006665 45 0.155
regulation of endothelial cell proliferation GO:0001936 23 0.154
digestive tract development GO:0048565 190 0.154
sympathetic neuron projection guidance GO:0097491 4 0.154
response to growth factor GO:0070848 198 0.153
endothelium development GO:0003158 45 0.151
regulation of chemotaxis GO:0050920 53 0.151
Mouse
intrahepatic bile duct development GO:0035622 2 0.151
cell junction assembly GO:0034329 52 0.151
Mouse
detection of stimulus GO:0051606 84 0.151
Mouse
divalent inorganic cation transport GO:0072511 178 0.151
cellular response to cytokine stimulus GO:0071345 189 0.150
negative regulation of phospholipase activity GO:0010519 4 0.150
central nervous system neuron development GO:0021954 67 0.149
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.149
epithelial cell development GO:0002064 159 0.149
spermatogenesis GO:0007283 284 0.148
epidermis development GO:0008544 187 0.148
Mouse
developmental induction GO:0031128 34 0.148
metal ion homeostasis GO:0055065 189 0.147
negative regulation of nervous system development GO:0051961 156 0.146
cardiac muscle tissue morphogenesis GO:0055008 44 0.146
negative regulation of phosphorus metabolic process GO:0010563 184 0.146
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.145
inner cell mass cellular morphogenesis GO:0001828 1 0.145
ascending aorta development GO:0035905 3 0.144
amide transport GO:0042886 138 0.142
respiratory tube development GO:0030323 167 0.142
epithelial tube morphogenesis GO:0060562 303 0.141
oligodendrocyte differentiation GO:0048709 53 0.139
Mouse
organophosphate catabolic process GO:0046434 232 0.139
cell migration involved in metanephros development GO:0035788 2 0.138
negative regulation of neuron differentiation GO:0045665 101 0.138
kidney vasculature morphogenesis GO:0061439 7 0.138
positive regulation of ion transport GO:0043270 65 0.138
regulation of erk1 and erk2 cascade GO:0070372 71 0.138
appendage morphogenesis GO:0035107 149 0.137
cellular response to organonitrogen compound GO:0071417 145 0.136
leukocyte migration GO:0050900 124 0.134
Mouse
tissue homeostasis GO:0001894 115 0.133
negative regulation of cellular component organization GO:0051129 194 0.132
cardiac muscle hypertrophy GO:0003300 23 0.132
branching morphogenesis of an epithelial tube GO:0048754 159 0.130
retina morphogenesis in camera type eye GO:0060042 45 0.130
mitral valve morphogenesis GO:0003183 4 0.130
cellular response to macrophage colony stimulating factor stimulus GO:0036006 3 0.130
cellular lipid metabolic process GO:0044255 323 0.129
central nervous system projection neuron axonogenesis GO:0021952 21 0.128
negative regulation of cell migration GO:0030336 59 0.128
Mouse
metanephric nephron development GO:0072210 34 0.128
cation transmembrane transport GO:0098655 266 0.127
gliogenesis GO:0042063 141 0.127
Mouse
cardiac atrium morphogenesis GO:0003209 23 0.127
adherens junction organization GO:0034332 28 0.127
circulatory system process GO:0003013 197 0.127
Mouse
macrophage colony stimulating factor signaling pathway GO:0038145 2 0.126
response to macrophage colony stimulating factor GO:0036005 3 0.126
negative regulation of hormone metabolic process GO:0032351 4 0.126
rho protein signal transduction GO:0007266 32 0.125
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.124
endocardial cell differentiation GO:0060956 4 0.122
carbohydrate homeostasis GO:0033500 128 0.122
muscle fiber development GO:0048747 76 0.122
regulation of ion transmembrane transporter activity GO:0032412 54 0.122
action potential GO:0001508 78 0.121
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.121
ascending aorta morphogenesis GO:0035910 3 0.121
purine ribonucleoside metabolic process GO:0046128 241 0.120
nucleobase containing small molecule metabolic process GO:0055086 352 0.120
endocardium formation GO:0060214 4 0.119
response to decreased oxygen levels GO:0036293 59 0.119
germ cell development GO:0007281 185 0.119
regulation of cellular component biogenesis GO:0044087 181 0.119
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.118
glomerulus vasculature development GO:0072012 14 0.118
response to amino acid GO:0043200 37 0.118
cell chemotaxis GO:0060326 81 0.117
Mouse
nephron tubule development GO:0072080 84 0.117
embryonic heart tube morphogenesis GO:0003143 51 0.117
anatomical structure homeostasis GO:0060249 145 0.117
regulation of blood pressure GO:0008217 93 0.117
Mouse
negative regulation of endothelial cell apoptotic process GO:2000352 7 0.116
negative regulation of sodium ion transmembrane transporter activity GO:2000650 1 0.116
actin filament organization GO:0007015 113 0.116
peptidyl serine phosphorylation GO:0018105 74 0.115
melanocyte adhesion GO:0097326 1 0.115
purine nucleoside triphosphate catabolic process GO:0009146 203 0.115
developmental growth involved in morphogenesis GO:0060560 138 0.113
negative regulation of growth GO:0045926 99 0.113
skeletal system development GO:0001501 356 0.113
positive regulation of cell motility GO:2000147 116 0.112
Mouse
regulation of rho gtpase activity GO:0032319 58 0.112
nucleotide catabolic process GO:0009166 217 0.111
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.111
megakaryocyte differentiation GO:0030219 26 0.111
muscle cell proliferation GO:0033002 52 0.110
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.109
cellular chemical homeostasis GO:0055082 215 0.108
forebrain morphogenesis GO:0048853 17 0.108
response to heparin GO:0071503 1 0.108
lung morphogenesis GO:0060425 50 0.107
protein localization to plasma membrane GO:0072659 57 0.107
regionalization GO:0003002 337 0.107
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.106
b cell activation GO:0042113 161 0.106
cell cell junction organization GO:0045216 72 0.106
Mouse
cardiac muscle tissue growth GO:0055017 37 0.106
establishment or maintenance of cell polarity GO:0007163 86 0.105
regulation of neuron differentiation GO:0045664 281 0.104
positive regulation of lipid metabolic process GO:0045834 40 0.103
forebrain generation of neurons GO:0021872 63 0.103
digestion GO:0007586 40 0.102
response to oxygen levels GO:0070482 62 0.102
pigmentation GO:0043473 71 0.102
genitalia development GO:0048806 37 0.101
cellular response to dna damage stimulus GO:0006974 207 0.100
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.100
nucleotide metabolic process GO:0009117 332 0.099
sensory perception of sound GO:0007605 97 0.098
Mouse
brain morphogenesis GO:0048854 32 0.098
regulation of blood circulation GO:1903522 93 0.098
mesenchyme morphogenesis GO:0072132 32 0.098
negative regulation of cellular protein metabolic process GO:0032269 247 0.098
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.097
response to acid chemical GO:0001101 111 0.097
endodermal digestive tract morphogenesis GO:0061031 4 0.096
regulation of actin filament based process GO:0032970 99 0.096
drug catabolic process GO:0042737 2 0.096
response to transforming growth factor beta GO:0071559 88 0.095
metanephric nephron epithelium development GO:0072243 19 0.095
plasma membrane organization GO:0007009 90 0.095
limb morphogenesis GO:0035108 149 0.095
kidney morphogenesis GO:0060993 83 0.094
development of primary male sexual characteristics GO:0046546 88 0.094
venous blood vessel development GO:0060841 13 0.093
neuromuscular process controlling balance GO:0050885 59 0.093
Mouse
calcium ion transmembrane transport GO:0070588 85 0.093
regulation of cardiac cell fate specification GO:2000043 1 0.093
odontogenesis of dentin containing tooth GO:0042475 66 0.092
metencephalon development GO:0022037 89 0.092
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.092
heart growth GO:0060419 45 0.092
tripeptide transport GO:0042939 1 0.092
negative regulation of cell motility GO:2000146 61 0.092
Mouse
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.092
regulation of cardiac muscle tissue development GO:0055024 31 0.091
gonad development GO:0008406 141 0.091
negative regulation of axon extension GO:0030517 19 0.091
lymphoid progenitor cell differentiation GO:0002320 17 0.090
inner ear morphogenesis GO:0042472 101 0.090
Mouse
regulation of lipid metabolic process GO:0019216 118 0.090
regulation of axon extension GO:0030516 43 0.090
epithelial tube formation GO:0072175 130 0.089
ras protein signal transduction GO:0007265 77 0.089
response to retinoic acid GO:0032526 56 0.089
cellular response to hormone stimulus GO:0032870 150 0.088
calcium ion homeostasis GO:0055074 127 0.087
hair cycle GO:0042633 90 0.087
homotypic cell cell adhesion GO:0034109 28 0.087
trabecula morphogenesis GO:0061383 40 0.087
regulation of kidney development GO:0090183 40 0.086
nuclear division GO:0000280 158 0.086
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.086
regulation of protein stability GO:0031647 52 0.086
commissural neuron axon guidance GO:0071679 8 0.086
regulation of lymphocyte activation GO:0051249 240 0.085
endoderm development GO:0007492 45 0.085
homeostasis of number of cells GO:0048872 210 0.085
glucose homeostasis GO:0042593 128 0.085
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.085
regulation of cell growth GO:0001558 91 0.085
cerebellar cortex formation GO:0021697 22 0.084
mitral valve development GO:0003174 4 0.084
regulation of apoptotic signaling pathway GO:2001233 197 0.084
positive regulation of g0 to g1 transition GO:0070318 2 0.084
granulocyte chemotaxis GO:0071621 39 0.083
Mouse
regulation of muscle hypertrophy GO:0014743 13 0.083
potassium ion transmembrane transport GO:0071805 43 0.083
muscle cell migration GO:0014812 19 0.083
positive regulation of transferase activity GO:0051347 167 0.083
endocardial cushion morphogenesis GO:0003203 18 0.083
cell division GO:0051301 120 0.083
establishment of protein localization to membrane GO:0090150 54 0.082
positive regulation of extracellular matrix organization GO:1903055 4 0.082
establishment of endothelial blood brain barrier GO:0014045 3 0.081
regulation of fibroblast proliferation GO:0048145 34 0.081
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.081
actin filament based movement GO:0030048 23 0.081
spinal cord development GO:0021510 81 0.081
regulation of cell cycle GO:0051726 281 0.080
negative regulation of angiogenesis GO:0016525 25 0.080
coronary vasculature morphogenesis GO:0060977 9 0.079
ribose phosphate metabolic process GO:0019693 291 0.079
leukocyte mediated immunity GO:0002443 174 0.079
phosphatidylinositol metabolic process GO:0046488 45 0.079
cerebral cortex development GO:0021987 86 0.078
cytokine production GO:0001816 319 0.078
mammary gland morphogenesis GO:0060443 54 0.078
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.078
cell growth GO:0016049 130 0.077
positive regulation of rho gtpase activity GO:0032321 41 0.077
cardiogenic plate morphogenesis GO:0003142 1 0.077
purine ribonucleoside catabolic process GO:0046130 205 0.076
central nervous system neuron axonogenesis GO:0021955 28 0.076

Ptprb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.271
cardiovascular system disease DOID:1287 0 0.271
muscular disease DOID:0080000 0 0.148
musculoskeletal system disease DOID:17 0 0.148
muscle tissue disease DOID:66 0 0.148
myopathy DOID:423 0 0.125
heart disease DOID:114 0 0.125
cardiomyopathy DOID:0050700 0 0.125
intrinsic cardiomyopathy DOID:0060036 0 0.125