|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.791
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.788
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.737
|
Fly |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.718
|
Mouse |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.694
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.621
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.595
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.584
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.584
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.580
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.570
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.550
|
Fly |
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.544
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.504
|
Mouse |
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.502
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.475
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.462
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.439
|
Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.413
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.412
|
Mouse |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.411
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.406
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.403
|
Mouse |
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.399
|
Mouse |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.386
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.380
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.380
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.360
|
Mouse |
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.355
|
Mouse |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.348
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.345
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.343
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.341
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.340
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.339
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.339
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.330
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.329
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.329
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.324
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.319
|
Zebrafish |
|
|
filtration diaphragm assembly
|
GO:0036058 |
1 |
0.317
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.313
|
Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.305
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.303
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.301
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.300
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.300
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.299
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.298
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.297
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.294
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.293
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.292
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.291
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.290
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.287
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.286
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.276
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.275
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.274
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.273
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.270
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.268
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.266
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.266
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.266
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.265
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.264
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.264
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.260
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.259
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.258
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.256
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.255
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.252
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.252
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.242
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.242
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.242
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.240
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.239
|
Mouse |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.239
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.231
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.230
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.227
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.227
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.227
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.224
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.223
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.222
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.221
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.220
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.219
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.218
|
Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.217
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.214
|
Mouse |
|
|
gastrulation
|
GO:0007369 |
116 |
0.212
|
Zebrafish |
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.212
|
Mouse |
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.211
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.210
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.210
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.209
|
Mouse |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.206
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.204
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.204
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.202
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.202
|
Mouse |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.201
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.198
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.197
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.195
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.192
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.192
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.191
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.191
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.191
|
Mouse |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.189
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.189
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.188
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.188
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.185
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.185
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.183
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.182
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.180
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.177
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.175
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.174
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.173
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.170
|
Mouse |
|
|
cellularization
|
GO:0007349 |
1 |
0.170
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.170
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.168
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.168
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.166
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.165
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.165
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.164
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.163
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.162
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.160
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.160
|
Mouse |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.158
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.156
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.156
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.156
|
Mouse |
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.153
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.152
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.152
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.151
|
Mouse |
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.151
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.151
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.150
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.150
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.149
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.149
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.148
|
Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.146
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.145
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.145
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.142
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.142
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.142
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.140
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.140
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.140
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.140
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.140
|
Mouse |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.139
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.139
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.138
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.138
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.137
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.137
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.137
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.137
|
Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.137
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.137
|
|
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.136
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.136
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.136
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.136
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.135
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.135
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.134
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.134
|
Mouse |
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.133
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.133
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.132
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.132
|
Mouse |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.132
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.131
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.131
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.131
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.130
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.129
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.128
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.128
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.128
|
Mouse |
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.126
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.125
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.123
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.123
|
Mouse |
|
|
glucose transport
|
GO:0015758 |
56 |
0.123
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.122
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.121
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.121
|
Mouse |
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.119
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.119
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.119
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.118
|
Mouse |
|
|
neuron migration
|
GO:0001764 |
122 |
0.118
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.118
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.116
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.115
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.115
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.115
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.114
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.114
|
|
|
|
epidermal growth factor receptor signaling pathway via i kappab kinase nf kappab cascade
|
GO:0038168 |
1 |
0.113
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.112
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.112
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.111
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.111
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.111
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.111
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.111
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.111
|
Mouse |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.110
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.109
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.109
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.108
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.108
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.107
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.107
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.107
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.106
|
Mouse |
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.106
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.106
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.106
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.105
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.105
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.105
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.105
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.105
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.105
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.104
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.104
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.104
|
Mouse |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.104
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.103
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.102
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.102
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.102
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.102
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.102
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.102
|
Mouse |
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.102
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.102
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.102
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.101
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.101
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.101
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.101
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.100
|
Zebrafish |
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.100
|
|
|
|
memory
|
GO:0007613 |
58 |
0.099
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.099
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.099
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.099
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.099
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.097
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.097
|
Mouse |
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.097
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.096
|
Mouse |
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.096
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.096
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.096
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.095
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.095
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.095
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.095
|
Mouse |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.094
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.094
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.094
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.093
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.093
|
Mouse |
|
|
response to alcohol
|
GO:0097305 |
48 |
0.092
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.092
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.091
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.091
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.090
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.090
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.089
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.089
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.089
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.089
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.089
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.088
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.087
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.087
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.087
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.086
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.086
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.086
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.085
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.085
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.085
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.085
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.084
|
Mouse |
|
|
hexose transport
|
GO:0008645 |
56 |
0.084
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.084
|
Mouse |
|
|
bone remodeling
|
GO:0046849 |
53 |
0.084
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.084
|
Mouse |
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.083
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.083
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.082
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.081
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.081
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.080
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.080
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.080
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.079
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.078
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.078
|
|
|
|
negative regulation of mast cell proliferation
|
GO:0070667 |
1 |
0.078
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.077
|
Mouse |
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
3 |
0.077
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.077
|
Mouse |
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.077
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.076
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.076
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.075
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.075
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.075
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.075
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.075
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.073
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.073
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.073
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.073
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.072
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.072
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.072
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.071
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.071
|
Mouse |
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.071
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.070
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.070
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.070
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.070
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.070
|
Mouse |
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.070
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.068
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.068
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.068
|
Mouse |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.068
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.067
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.067
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.067
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.067
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.067
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.067
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.066
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.066
|
Mouse |
|
|
gonad development
|
GO:0008406 |
141 |
0.065
|
|
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
23 |
0.065
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.065
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.065
|
|
|
|
response to platelet derived growth factor
|
GO:0036119 |
6 |
0.064
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.064
|
Zebrafish |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.064
|
Mouse |
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.064
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.063
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.062
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.062
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.062
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.061
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.061
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.060
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.060
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.060
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.060
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.059
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.059
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.059
|
Mouse |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.059
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.059
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.059
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.058
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.058
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
6 |
0.058
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.058
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.058
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.058
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.058
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.058
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.058
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.057
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.057
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.057
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.057
|
Mouse |
|
|
intestinal epithelial cell differentiation
|
GO:0060575 |
14 |
0.057
|
|
|
|
peptidyl tyrosine autophosphorylation
|
GO:0038083 |
5 |
0.056
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.056
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.055
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.055
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.055
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.055
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.055
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.055
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.054
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.054
|
Mouse |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.054
|
Mouse |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.054
|
Mouse |
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.054
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.053
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.053
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.053
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.053
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.053
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.053
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.052
|
Mouse |
|
|
spindle localization
|
GO:0051653 |
22 |
0.052
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.052
|
|
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.052
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.052
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.051
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.051
|
|
|
|
parallel actin filament bundle assembly
|
GO:0030046 |
2 |
0.051
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.051
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.051
|
Mouse |
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.051
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.050
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.050
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.050
|
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.050
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.050
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.050
|
Mouse |
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
18 |
0.050
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.049
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.049
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.048
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.048
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.048
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.048
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.047
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.047
|
Mouse |
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.047
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.047
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.047
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.047
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.046
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.046
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.046
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.046
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.045
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.045
|
Mouse |
|
|
positive regulation of organelle assembly
|
GO:1902117 |
8 |
0.045
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.045
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.045
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.045
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.045
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.045
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.044
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.044
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.044
|
Mouse |
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.044
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.044
|
Mouse |
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.044
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.043
|
Mouse |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.043
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.043
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.043
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.043
|
Mouse |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.043
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.043
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.042
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.042
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.042
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.042
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.042
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.042
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.042
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.041
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.041
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.041
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.041
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.041
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
11 |
0.040
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.040
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.040
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.040
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.040
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.040
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.040
|
Mouse |
