Mus musculus

126 known processes

Ptpro

protein tyrosine phosphatase, receptor type, O

(Aliases: D28,PTPphi,PTPROt,PTPBK,GLEPP1,Ptpn15,PTPU2,PTPoc)

Ptpro biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 0.339
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.316
ion transmembrane transport GO:0034220 361 0.281
transmembrane transport GO:0055085 412 0.223
cellular ketone metabolic process GO:0042180 84 0.205
sequestering of metal ion GO:0051238 19 0.187
inorganic ion transmembrane transport GO:0098660 234 0.184
cation transmembrane transport GO:0098655 266 0.169
actin cytoskeleton organization GO:0030036 220 0.168
amine metabolic process GO:0009308 45 0.167
second messenger mediated signaling GO:0019932 73 0.161
sequestering of calcium ion GO:0051208 18 0.156
cation homeostasis GO:0055080 212 0.155
positive regulation of secretion GO:0051047 130 0.152
synaptic transmission GO:0007268 329 0.151
cellular chemical homeostasis GO:0055082 215 0.150
purine ribonucleotide metabolic process GO:0009150 290 0.149
negative regulation of immune system process GO:0002683 209 0.147
Mouse
calcium ion homeostasis GO:0055074 127 0.146
cellular homeostasis GO:0019725 240 0.142
cation transport GO:0006812 399 0.140
regulation of cellular amine metabolic process GO:0033238 20 0.138
ribonucleotide metabolic process GO:0009259 291 0.137
cellular amino acid metabolic process GO:0006520 103 0.137
negative regulation of protein metabolic process GO:0051248 282 0.135
Mouse
single organismal cell cell adhesion GO:0016337 131 0.131
organonitrogen compound catabolic process GO:1901565 264 0.125
negative regulation of phosphorylation GO:0042326 166 0.123
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.123
Mouse
cellular amine metabolic process GO:0044106 44 0.122
regulation of purine nucleotide metabolic process GO:1900542 169 0.121
ras protein signal transduction GO:0007265 77 0.117
purine nucleotide metabolic process GO:0006163 302 0.115
cellular calcium ion homeostasis GO:0006874 119 0.114
inorganic cation transmembrane transport GO:0098662 207 0.114
small gtpase mediated signal transduction GO:0007264 97 0.113
regulation of protein kinase activity GO:0045859 232 0.111
Mouse
blood circulation GO:0008015 195 0.109
cytoplasmic transport GO:0016482 234 0.108
cognition GO:0050890 149 0.108
Fly
gtp catabolic process GO:0006184 143 0.104
organic anion transport GO:0015711 137 0.104
rho protein signal transduction GO:0007266 32 0.103
purine ribonucleotide catabolic process GO:0009154 208 0.103
negative regulation of protein modification process GO:0031400 163 0.103
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.102
regulation of organelle organization GO:0033043 289 0.102
guanosine containing compound metabolic process GO:1901068 144 0.100
nucleoside phosphate metabolic process GO:0006753 338 0.099
membrane organization GO:0061024 245 0.098
peptidyl amino acid modification GO:0018193 336 0.096
purine nucleotide catabolic process GO:0006195 211 0.096
immune effector process GO:0002252 321 0.095
calcium ion transport GO:0006816 159 0.095
regulation of cellular amino acid metabolic process GO:0006521 5 0.094
cellular divalent inorganic cation homeostasis GO:0072503 127 0.094
response to molecule of bacterial origin GO:0002237 143 0.094
ribonucleotide catabolic process GO:0009261 208 0.093
axonogenesis GO:0007409 274 0.093
regulation of secretion GO:0051046 274 0.093
myeloid cell differentiation GO:0030099 233 0.090
metal ion homeostasis GO:0055065 189 0.090
learning or memory GO:0007611 148 0.090
Fly
nucleoside metabolic process GO:0009116 246 0.089
regulation of intracellular transport GO:0032386 159 0.088
locomotory behavior GO:0007626 195 0.088
organic cyclic compound catabolic process GO:1901361 295 0.087
mapk cascade GO:0000165 281 0.085
Mouse
single organism cell adhesion GO:0098602 156 0.084
negative regulation of phosphorus metabolic process GO:0010563 184 0.082
Mouse
regulation of cell activation GO:0050865 289 0.081
Mouse
multicellular organismal signaling GO:0035637 91 0.080
ribose phosphate metabolic process GO:0019693 291 0.079
negative regulation of molecular function GO:0044092 258 0.077
Mouse
regulation of protein localization GO:0032880 231 0.077
ribonucleoside metabolic process GO:0009119 245 0.076
regulation of transferase activity GO:0051338 263 0.076
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.076
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.075
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.075
nucleoside triphosphate metabolic process GO:0009141 230 0.075
divalent inorganic cation homeostasis GO:0072507 138 0.075
guanosine containing compound catabolic process GO:1901069 144 0.075
sensory perception GO:0007600 245 0.072
Mouse
regulation of gtp catabolic process GO:0033124 113 0.072
nucleotide metabolic process GO:0009117 332 0.072
nucleoside phosphate catabolic process GO:1901292 222 0.072
nucleoside catabolic process GO:0009164 206 0.071
purine nucleoside triphosphate metabolic process GO:0009144 226 0.071
inflammatory response GO:0006954 244 0.071
regulation of cellular catabolic process GO:0031329 242 0.070
cellular metal ion homeostasis GO:0006875 151 0.070
regulation of lymphocyte activation GO:0051249 240 0.070
divalent inorganic cation transport GO:0072511 178 0.069
calcium ion transport into cytosol GO:0060402 48 0.069
regulation of hydrolase activity GO:0051336 246 0.069
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.069
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.068
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.068
regulation of map kinase activity GO:0043405 120 0.068
Mouse
regulation of system process GO:0044057 200 0.067
regulation of ion transport GO:0043269 215 0.066
regulation of kinase activity GO:0043549 249 0.066
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.065
negative regulation of cellular protein metabolic process GO:0032269 247 0.065
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.065
leukocyte activation involved in immune response GO:0002366 126 0.064
aromatic compound catabolic process GO:0019439 286 0.063
chemotaxis GO:0006935 247 0.063
organophosphate catabolic process GO:0046434 232 0.062
negative regulation of protein phosphorylation GO:0001933 126 0.062
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.060
regulation of secretion by cell GO:1903530 249 0.060
regulation of cellular ketone metabolic process GO:0010565 66 0.060
gtp metabolic process GO:0046039 144 0.060
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
regulation of nucleoside metabolic process GO:0009118 130 0.059
organic hydroxy compound metabolic process GO:1901615 203 0.059
response to lipopolysaccharide GO:0032496 128 0.059
cytosolic calcium ion transport GO:0060401 48 0.058
glycosyl compound metabolic process GO:1901657 246 0.058
purine containing compound metabolic process GO:0072521 311 0.056
organonitrogen compound biosynthetic process GO:1901566 192 0.055
negative regulation of cell proliferation GO:0008285 296 0.055
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.055
ribonucleoside triphosphate catabolic process GO:0009203 199 0.054
purine nucleoside metabolic process GO:0042278 241 0.054
dna metabolic process GO:0006259 303 0.054
hematopoietic progenitor cell differentiation GO:0002244 143 0.054
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.054
regulation of camp mediated signaling GO:0043949 7 0.053
myeloid leukocyte differentiation GO:0002573 119 0.053
cell growth GO:0016049 130 0.053
cellular ion homeostasis GO:0006873 165 0.052
t cell activation GO:0042110 289 0.051
nucleotide catabolic process GO:0009166 217 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.050
monocarboxylic acid metabolic process GO:0032787 191 0.050
calcium ion transmembrane transport GO:0070588 85 0.050
regulation of neuron projection development GO:0010975 169 0.049
divalent metal ion transport GO:0070838 172 0.049
regulation of synaptic plasticity GO:0048167 87 0.049
negative regulation of cell motility GO:2000146 61 0.049
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.049
purine ribonucleoside metabolic process GO:0046128 241 0.049
small molecule biosynthetic process GO:0044283 132 0.049
leukocyte differentiation GO:0002521 342 0.048
regulation of membrane potential GO:0042391 192 0.048
detection of stimulus GO:0051606 84 0.048
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.047
regulation of defense response GO:0031347 233 0.046
muscle system process GO:0003012 141 0.046
protein processing GO:0016485 163 0.046
immune response activating signal transduction GO:0002757 116 0.045
Mouse
regulation of response to wounding GO:1903034 189 0.045
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
nitrogen compound transport GO:0071705 271 0.045
cellular response to lipopolysaccharide GO:0071222 77 0.045
positive regulation of neuron projection development GO:0010976 79 0.045
regulation of ras protein signal transduction GO:0046578 114 0.044
regulation of neuron apoptotic process GO:0043523 122 0.044
regulation of neurotransmitter levels GO:0001505 87 0.044
regulation of blood circulation GO:1903522 93 0.044
renal system development GO:0072001 225 0.044
negative regulation of neuron apoptotic process GO:0043524 92 0.043
maintenance of location GO:0051235 89 0.043
regulation of transmembrane transport GO:0034762 128 0.043
regulation of protein serine threonine kinase activity GO:0071900 157 0.042
Mouse
neuron apoptotic process GO:0051402 142 0.042
positive regulation of gtp catabolic process GO:0033126 85 0.042
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.042
regulation of neuron death GO:1901214 134 0.042
learning GO:0007612 98 0.042
ribonucleoside catabolic process GO:0042454 206 0.041
anatomical structure homeostasis GO:0060249 145 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
regulation of ion transmembrane transport GO:0034765 119 0.040
action potential GO:0001508 78 0.040
innate immune response GO:0045087 157 0.040
regulation of ras gtpase activity GO:0032318 88 0.040
cell activation involved in immune response GO:0002263 126 0.039
regulation of cytoskeleton organization GO:0051493 122 0.039
regulation of nucleotide catabolic process GO:0030811 122 0.039
response to organonitrogen compound GO:0010243 246 0.039
regulation of mapk cascade GO:0043408 248 0.038
Mouse
positive regulation of dna biosynthetic process GO:2000573 4 0.038
regulation of ion homeostasis GO:2000021 64 0.038
regulation of cell motility GO:2000145 236 0.038
Mouse
oxidation reduction process GO:0055114 342 0.038
regulation of purine nucleotide catabolic process GO:0033121 122 0.038
muscle contraction GO:0006936 101 0.038
regulation of protein transport GO:0051223 163 0.037
male gamete generation GO:0048232 285 0.037
cell matrix adhesion GO:0007160 68 0.037
Mouse
rap protein signal transduction GO:0032486 3 0.037
purine containing compound catabolic process GO:0072523 213 0.037
nucleotide biosynthetic process GO:0009165 78 0.037
carbohydrate metabolic process GO:0005975 230 0.037
associative learning GO:0008306 61 0.036
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.036
cellular response to biotic stimulus GO:0071216 92 0.036
calcium mediated signaling GO:0019722 46 0.036
positive regulation of protein modification process GO:0031401 299 0.035
positive regulation of cytokine production GO:0001819 174 0.035
purine nucleoside catabolic process GO:0006152 205 0.035
multicellular organismal homeostasis GO:0048871 164 0.035
positive regulation of protein phosphorylation GO:0001934 242 0.035
exocytosis GO:0006887 121 0.035
heterocycle catabolic process GO:0046700 280 0.035
regulation of actin cytoskeleton organization GO:0032956 84 0.035
regulation of establishment of protein localization GO:0070201 181 0.035
organelle localization GO:0051640 179 0.035
leukocyte chemotaxis GO:0030595 69 0.035
Human Mouse
cellular lipid metabolic process GO:0044255 323 0.035
regulation of cytoplasmic transport GO:1903649 112 0.034
regulation of homeostatic process GO:0032844 182 0.034
neuronal action potential GO:0019228 54 0.034
regulation of exocytosis GO:0017157 61 0.034
positive regulation of cell activation GO:0050867 158 0.034
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.034
nucleoside triphosphate catabolic process GO:0009143 205 0.034
positive regulation of endocytosis GO:0045807 42 0.034
axon guidance GO:0007411 141 0.034
positive regulation of intracellular transport GO:0032388 70 0.034
positive regulation of nervous system development GO:0051962 221 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
mitotic cell cycle GO:0000278 195 0.033
kidney development GO:0001822 213 0.033
b cell activation GO:0042113 161 0.033
actin filament organization GO:0007015 113 0.033
neural tube development GO:0021915 160 0.033
negative regulation of synapse assembly GO:0051964 3 0.033
epidermis development GO:0008544 187 0.033
Mouse
central nervous system neuron differentiation GO:0021953 162 0.033
anion transport GO:0006820 177 0.033
release of sequestered calcium ion into cytosol GO:0051209 42 0.032
regulation of cytokine production GO:0001817 266 0.032
negative regulation of kinase activity GO:0033673 81 0.032
Mouse
protein localization to organelle GO:0033365 185 0.032
negative regulation of cell migration GO:0030336 59 0.032
Mouse
organic hydroxy compound transport GO:0015850 93 0.032
regulation of body fluid levels GO:0050878 162 0.032
regulation of neuron differentiation GO:0045664 281 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
regulation of actin filament based process GO:0032970 99 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
cytokine production GO:0001816 319 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
regulation of cell adhesion GO:0030155 154 0.031
Mouse
regulation of cell projection organization GO:0031344 206 0.031
positive regulation of innate immune response GO:0045089 80 0.031
protein modification by small protein conjugation or removal GO:0070647 207 0.031
memory GO:0007613 58 0.031
Fly
negative regulation of intracellular signal transduction GO:1902532 167 0.031
Mouse
single fertilization GO:0007338 82 0.031
positive regulation of defense response GO:0031349 124 0.031
positive regulation of hydrolase activity GO:0051345 148 0.030
peptidyl tyrosine modification GO:0018212 145 0.030
urogenital system development GO:0001655 261 0.030
phospholipid metabolic process GO:0006644 87 0.030
positive regulation of gtpase activity GO:0043547 85 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.030
positive regulation of secretion by cell GO:1903532 114 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.029
positive regulation of cell migration GO:0030335 109 0.029
Mouse
leukocyte proliferation GO:0070661 172 0.029
ossification GO:0001503 216 0.029
regulation of rho gtpase activity GO:0032319 58 0.029
cardiac muscle contraction GO:0060048 32 0.029
response to extracellular stimulus GO:0009991 127 0.029
regulation of ion transmembrane transporter activity GO:0032412 54 0.029
extracellular structure organization GO:0043062 148 0.029
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.029
cellular response to lipid GO:0071396 145 0.029
cellular carbohydrate metabolic process GO:0044262 119 0.029
immunoglobulin production GO:0002377 73 0.029
lymphocyte proliferation GO:0046651 164 0.029
carbohydrate homeostasis GO:0033500 128 0.028
regulation of calcium ion transport into cytosol GO:0010522 31 0.028
negative regulation of cell activation GO:0050866 111 0.028
muscle tissue development GO:0060537 308 0.028
positive regulation of rho gtpase activity GO:0032321 41 0.028
positive regulation of map kinase activity GO:0043406 84 0.028
regulation of anatomical structure size GO:0090066 178 0.028
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
leukocyte mediated immunity GO:0002443 174 0.028
alcohol metabolic process GO:0006066 116 0.028
regulation of hormone levels GO:0010817 211 0.027
transmission of nerve impulse GO:0019226 76 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
adult behavior GO:0030534 135 0.027
glycerolipid metabolic process GO:0046486 122 0.027
positive regulation of growth GO:0045927 104 0.027
heart process GO:0003015 94 0.027
positive regulation of homeostatic process GO:0032846 64 0.027
skeletal system development GO:0001501 356 0.027
regulation of endocytosis GO:0030100 69 0.027
synapse organization GO:0050808 125 0.027
cell type specific apoptotic process GO:0097285 268 0.027
reactive nitrogen species metabolic process GO:2001057 0 0.026
organic acid transport GO:0015849 101 0.026
positive regulation of apoptotic process GO:0043065 217 0.026
leukocyte migration GO:0050900 124 0.026
Human Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.026
activation of immune response GO:0002253 138 0.026
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.026
response to light stimulus GO:0009416 135 0.026
regulation of myeloid leukocyte differentiation GO:0002761 58 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
lymphocyte activation involved in immune response GO:0002285 93 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
negative regulation of camp mediated signaling GO:0043951 3 0.025
positive regulation of mapk cascade GO:0043410 170 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.025
positive regulation of cardiac muscle contraction GO:0060452 2 0.025
regulation of muscle system process GO:0090257 80 0.025
protein ubiquitination GO:0016567 171 0.025
endocytosis GO:0006897 168 0.025
regulation of cell cycle GO:0051726 281 0.025
positive regulation of cell motility GO:2000147 116 0.024
Mouse
vesicle localization GO:0051648 86 0.024
digestive tract development GO:0048565 190 0.024
regulation of transporter activity GO:0032409 57 0.024
response to radiation GO:0009314 165 0.024
regulation of inflammatory response GO:0050727 147 0.024
multicellular organism growth GO:0035264 161 0.024
immune response regulating signaling pathway GO:0002764 125 0.024
Mouse
cytokine secretion GO:0050663 72 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
cell substrate adhesion GO:0031589 130 0.023
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.023
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.023
circulatory system process GO:0003013 197 0.023
embryonic epithelial tube formation GO:0001838 130 0.023
tissue homeostasis GO:0001894 115 0.023
rac protein signal transduction GO:0016601 13 0.023
regulation of cellular response to stress GO:0080135 159 0.023
organic acid biosynthetic process GO:0016053 86 0.023
negative regulation of cell development GO:0010721 169 0.022
epithelial cell proliferation GO:0050673 174 0.022
neuron death GO:0070997 154 0.022
connective tissue development GO:0061448 179 0.022
gliogenesis GO:0042063 141 0.022
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.022
osteoclast differentiation GO:0030316 62 0.022
mitotic cell cycle process GO:1903047 159 0.022
placenta development GO:0001890 140 0.022
glycerophospholipid metabolic process GO:0006650 71 0.022
establishment or maintenance of cell polarity GO:0007163 86 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
protein oligomerization GO:0051259 67 0.022
lymphocyte mediated immunity GO:0002449 139 0.022
gastrulation GO:0007369 116 0.022
regulation of t cell activation GO:0050863 170 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.021
regulation of lipid metabolic process GO:0019216 118 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
regulation of multi organism process GO:0043900 111 0.021
protein secretion GO:0009306 111 0.021
adult locomotory behavior GO:0008344 91 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
regulation of production of molecular mediator of immune response GO:0002700 65 0.021
negative regulation of phospholipase activity GO:0010519 4 0.021
camp mediated signaling GO:0019933 15 0.021
plasma membrane organization GO:0007009 90 0.021
activation of mapk activity GO:0000187 59 0.021
neuron neuron synaptic transmission GO:0007270 69 0.021
calcium ion dependent exocytosis GO:0017156 35 0.021
positive regulation of cell projection organization GO:0031346 95 0.021
positive regulation of ras gtpase activity GO:0032320 65 0.021
positive regulation of cell development GO:0010720 237 0.021
negative regulation of growth GO:0045926 99 0.021
negative regulation of cytokine production GO:0001818 84 0.021
angiogenesis GO:0001525 201 0.020
Mouse
cyclic nucleotide metabolic process GO:0009187 59 0.020
primary neural tube formation GO:0014020 95 0.020
b cell mediated immunity GO:0019724 71 0.020
apoptotic signaling pathway GO:0097190 306 0.020
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.020
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.020
sensory perception of mechanical stimulus GO:0050954 107 0.020
Mouse
olfactory learning GO:0008355 2 0.020
developmental cell growth GO:0048588 84 0.020
telencephalon development GO:0021537 186 0.020
muscle cell differentiation GO:0042692 261 0.020
regulation of leukocyte mediated immunity GO:0002703 104 0.020
establishment of organelle localization GO:0051656 122 0.020
protein maturation GO:0051604 176 0.020
regulation of metal ion transport GO:0010959 106 0.020
dendrite development GO:0016358 115 0.020
lipid biosynthetic process GO:0008610 179 0.020
brown fat cell differentiation GO:0050873 36 0.020
positive regulation of nucleoside metabolic process GO:0045979 91 0.020
organic acid catabolic process GO:0016054 51 0.020
blood vessel morphogenesis GO:0048514 285 0.020
Mouse
bone development GO:0060348 120 0.020
regulation of vasculature development GO:1901342 88 0.020
regulation of myeloid cell differentiation GO:0045637 96 0.020
protein catabolic process GO:0030163 221 0.020
fat cell differentiation GO:0045444 160 0.019
regulation of b cell activation GO:0050864 81 0.019
smooth muscle contraction GO:0006939 44 0.019
neural tube formation GO:0001841 108 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
positive regulation of transferase activity GO:0051347 167 0.019
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.019
Mouse
organophosphate biosynthetic process GO:0090407 122 0.019
positive regulation of striated muscle contraction GO:0045989 3 0.019
negative regulation of neuron projection development GO:0010977 50 0.019
multicellular organismal response to stress GO:0033555 62 0.019
stress activated protein kinase signaling cascade GO:0031098 81 0.019
vesicle organization GO:0016050 60 0.019
regulation of jnk cascade GO:0046328 62 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
regulation of cell growth GO:0001558 91 0.019
response to organic cyclic compound GO:0014070 198 0.019
positive regulation of inflammatory response GO:0050729 47 0.019
establishment of vesicle localization GO:0051650 81 0.019
glycoprotein metabolic process GO:0009100 116 0.019
amino acid transport GO:0006865 61 0.019
synaptic vesicle transport GO:0048489 57 0.019
glial cell differentiation GO:0010001 131 0.019
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
heart morphogenesis GO:0003007 178 0.018
peptide secretion GO:0002790 114 0.018
spermatogenesis GO:0007283 284 0.018
response to growth factor GO:0070848 198 0.018
neuron migration GO:0001764 122 0.018
microtubule based process GO:0007017 236 0.018
cgmp catabolic process GO:0046069 2 0.018
sensory perception of sound GO:0007605 97 0.018
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
negative regulation of neuron death GO:1901215 98 0.018
stem cell differentiation GO:0048863 268 0.018
organelle assembly GO:0070925 177 0.018
lymphocyte differentiation GO:0030098 242 0.018
protein import into nucleus GO:0006606 95 0.018
phenol containing compound metabolic process GO:0018958 60 0.018
fertilization GO:0009566 127 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
cellular response to external stimulus GO:0071496 88 0.018
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.018
regulation of intracellular protein transport GO:0033157 82 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
cerebellum development GO:0021549 77 0.017
negative regulation of hydrolase activity GO:0051346 71 0.017
negative regulation of response to wounding GO:1903035 77 0.017
epithelial cell development GO:0002064 159 0.017
protein targeting GO:0006605 143 0.017
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.017
response to nutrient levels GO:0031667 109 0.017
neuron projection guidance GO:0097485 141 0.017
regulation of cation channel activity GO:2001257 22 0.017
striated muscle tissue development GO:0014706 293 0.017
regulation of exit from mitosis GO:0007096 1 0.017
neuron projection extension GO:1990138 64 0.017
jnk cascade GO:0007254 72 0.017
regulation of calcium ion transmembrane transport GO:1903169 20 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.017
granulocyte chemotaxis GO:0071621 39 0.017
Mouse
regulation of peptidase activity GO:0052547 96 0.017
tube formation GO:0035148 140 0.017
cellular response to abiotic stimulus GO:0071214 56 0.017
cellularization GO:0007349 1 0.016
endomembrane system organization GO:0010256 147 0.016
defense response to virus GO:0051607 68 0.016
regulation of reproductive process GO:2000241 66 0.016
cellular protein complex assembly GO:0043623 116 0.016
regulation of muscle contraction GO:0006937 49 0.016
response to transforming growth factor beta GO:0071559 88 0.016
establishment of glial blood brain barrier GO:0060857 2 0.016
gland development GO:0048732 330 0.016
digestive system development GO:0055123 200 0.016
synaptic vesicle localization GO:0097479 59 0.016
b cell differentiation GO:0030183 78 0.016
macrophage differentiation GO:0030225 20 0.016
regulation of proteolysis GO:0030162 164 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
positive regulation of organelle organization GO:0010638 128 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
lipid modification GO:0030258 65 0.016
mitochondrion distribution GO:0048311 4 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
adaptive immune response GO:0002250 155 0.016
dephosphorylation GO:0016311 129 0.016
hemostasis GO:0007599 78 0.016
Mouse
response to drug GO:0042493 75 0.016
developmental maturation GO:0021700 193 0.016
phagocytosis GO:0006909 66 0.015

Ptpro disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
Human
nervous system disease DOID:863 0 0.047
central nervous system disease DOID:331 0 0.023
sensory system disease DOID:0050155 0 0.021