Mus musculus

74 known processes

Ptprq

protein tyrosine phosphatase, receptor type, Q

Ptprq biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
photoreceptor cell maintenance GO:0045494 19 0.938
vestibular receptor cell development GO:0060118 2 0.938
inner ear receptor cell development GO:0060119 39 0.910
retina homeostasis GO:0001895 23 0.882
auditory receptor cell morphogenesis GO:0002093 15 0.874
inner ear receptor stereocilium organization GO:0060122 23 0.808
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.712
inner ear receptor cell differentiation GO:0060113 61 0.663
ear development GO:0043583 200 0.576
equilibrioception GO:0050957 3 0.557
actin cytoskeleton organization GO:0030036 220 0.544
actin filament organization GO:0007015 113 0.525
detection of mechanical stimulus GO:0050982 27 0.513
skin development GO:0043588 220 0.500
inner ear morphogenesis GO:0042472 101 0.498
auditory receptor cell stereocilium organization GO:0060088 12 0.470
mechanoreceptor differentiation GO:0042490 67 0.447
ear morphogenesis GO:0042471 118 0.436
sensory perception of mechanical stimulus GO:0050954 107 0.412
epidermis development GO:0008544 187 0.385
sensory organ morphogenesis GO:0090596 242 0.348
regulation of cytoskeleton organization GO:0051493 122 0.338
negative regulation of cell proliferation GO:0008285 296 0.337
Mouse
parallel actin filament bundle assembly GO:0030046 2 0.315
sensory perception of sound GO:0007605 97 0.305
sensory perception GO:0007600 245 0.294
neuromuscular process controlling balance GO:0050885 59 0.281
mitotic cell cycle process GO:1903047 159 0.277
myosin filament organization GO:0031033 3 0.270
hair cell differentiation GO:0035315 40 0.268
cell cell junction organization GO:0045216 72 0.263
Mouse
endothelial cell development GO:0001885 20 0.252
multicellular organismal homeostasis GO:0048871 164 0.212
sensory perception of light stimulus GO:0050953 54 0.199
cell junction organization GO:0034330 77 0.196
Mouse
actin filament bundle assembly GO:0051017 40 0.190
myosin filament assembly GO:0031034 2 0.189
ubiquitin dependent protein catabolic process GO:0006511 129 0.184
protein localization to plasma membrane GO:0072659 57 0.176
post embryonic organ morphogenesis GO:0048563 8 0.170
mitotic cell cycle GO:0000278 195 0.167
regulation of actin cytoskeleton organization GO:0032956 84 0.161
detection of stimulus GO:0051606 84 0.159
cell adhesion GO:0007155 329 0.158
Mouse
cytokinetic process GO:0032506 2 0.156
single organism cell adhesion GO:0098602 156 0.151
endothelial cell differentiation GO:0045446 41 0.150
regulation of vesicle mediated transport GO:0060627 139 0.149
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.143
establishment or maintenance of cell polarity GO:0007163 86 0.139
striated muscle myosin thick filament assembly GO:0071688 1 0.137
negative regulation of molecular function GO:0044092 258 0.135
Mouse
regulation of protein localization GO:0032880 231 0.133
oocyte anterior posterior axis specification GO:0007314 2 0.131
cellular component assembly involved in morphogenesis GO:0010927 139 0.127
microtubule based movement GO:0007018 84 0.119
oocyte construction GO:0007308 2 0.116
spindle localization GO:0051653 22 0.114
tissue homeostasis GO:0001894 115 0.114
protein localization to membrane GO:0072657 108 0.110
detection of external stimulus GO:0009581 61 0.107
endocytosis GO:0006897 168 0.103
nonmotile primary cilium assembly GO:0035058 8 0.097
muscle cell differentiation GO:0042692 261 0.095
negative regulation of phosphorus metabolic process GO:0010563 184 0.093
Mouse
organelle localization GO:0051640 179 0.093
embryonic organ morphogenesis GO:0048562 276 0.092
epithelial cell development GO:0002064 159 0.091
establishment of organelle localization GO:0051656 122 0.089
cation homeostasis GO:0055080 212 0.089
nitrogen compound transport GO:0071705 271 0.086
axonogenesis GO:0007409 274 0.082
Mouse Fly
oocyte axis specification GO:0007309 2 0.082
digestive tract development GO:0048565 190 0.082
peptide cross linking GO:0018149 10 0.081
microtubule cytoskeleton organization GO:0000226 157 0.081
regulation of actin filament based process GO:0032970 99 0.080
auditory receptor cell development GO:0060117 20 0.080
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.079
regulation of organelle organization GO:0033043 289 0.079
purine ribonucleoside metabolic process GO:0046128 241 0.078
negative regulation of cellular protein metabolic process GO:0032269 247 0.074
Mouse
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.073
neuromuscular process GO:0050905 99 0.071
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.071
positive regulation of endocytosis GO:0045807 42 0.070
regulation of protein stability GO:0031647 52 0.068
nucleoside monophosphate catabolic process GO:0009125 59 0.067
visual perception GO:0007601 52 0.067
modification dependent protein catabolic process GO:0019941 133 0.066
regulation of cell cycle GO:0051726 281 0.065
posttranscriptional regulation of gene expression GO:0010608 155 0.063
mitotic sister chromatid separation GO:0051306 9 0.063
microtubule based process GO:0007017 236 0.062
response to organonitrogen compound GO:0010243 246 0.061
endomembrane system organization GO:0010256 147 0.061
oligopeptide transmembrane transport GO:0035672 4 0.059
negative regulation of kinase activity GO:0033673 81 0.058
Mouse
maternal determination of anterior posterior axis embryo GO:0008358 2 0.057
cellular protein catabolic process GO:0044257 155 0.057
nuclear division GO:0000280 158 0.057
odontogenesis GO:0042476 78 0.056
membrane organization GO:0061024 245 0.056
negative regulation of phosphorylation GO:0042326 166 0.055
Mouse
regulation of chromosome organization GO:0033044 83 0.054
positive regulation of cell adhesion GO:0045785 80 0.053
Mouse
synaptic transmission GO:0007268 329 0.052
regulation of endocytosis GO:0030100 69 0.051
ectoderm development GO:0007398 15 0.051
negative regulation of protein modification process GO:0031400 163 0.051
Mouse
phagosome maturation GO:0090382 4 0.051
forebrain development GO:0030900 302 0.050
camera type eye development GO:0043010 266 0.050
plasma membrane organization GO:0007009 90 0.049
anatomical structure homeostasis GO:0060249 145 0.048
inorganic ion transmembrane transport GO:0098660 234 0.048
regulation of chromosome segregation GO:0051983 21 0.047
regulation of protein localization to nucleus GO:1900180 60 0.046
odontogenesis of dentin containing tooth GO:0042475 66 0.046
divalent metal ion transport GO:0070838 172 0.046
regulation of system process GO:0044057 200 0.045
Mouse
eye photoreceptor cell development GO:0042462 31 0.045
negative regulation of protein metabolic process GO:0051248 282 0.045
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.045
negative regulation of mapk cascade GO:0043409 65 0.043
Mouse
germ cell development GO:0007281 185 0.043
establishment of mitotic spindle localization GO:0040001 12 0.043
mitotic nuclear division GO:0007067 48 0.042
regulation of membrane potential GO:0042391 192 0.042
nucleotide catabolic process GO:0009166 217 0.042
tube formation GO:0035148 140 0.042
chromosome segregation GO:0007059 48 0.041
multicellular organism growth GO:0035264 161 0.041
cilium morphogenesis GO:0060271 102 0.040
neural precursor cell proliferation GO:0061351 121 0.040
single organismal cell cell adhesion GO:0016337 131 0.039
cellular protein complex assembly GO:0043623 116 0.039
regulation of mitotic sister chromatid segregation GO:0033047 12 0.038
regulation of synaptic plasticity GO:0048167 87 0.038
regulation of cell division GO:0051302 76 0.038
cilium assembly GO:0042384 81 0.038
macromolecule catabolic process GO:0009057 281 0.038
regulation of protein kinase activity GO:0045859 232 0.037
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.036
oocyte differentiation GO:0009994 35 0.036
gastrulation GO:0007369 116 0.036
auditory receptor cell differentiation GO:0042491 37 0.036
chromosome separation GO:0051304 14 0.036
regulation of nuclear division GO:0051783 56 0.036
proteasomal protein catabolic process GO:0010498 98 0.036
regulation of hydrolase activity GO:0051336 246 0.035
endothelium development GO:0003158 45 0.035
response to light stimulus GO:0009416 135 0.035
digestive system development GO:0055123 200 0.035
rho protein signal transduction GO:0007266 32 0.034
post embryonic organ development GO:0048569 17 0.034
Worm
vesicle localization GO:0051648 86 0.034
nucleoside triphosphate catabolic process GO:0009143 205 0.034
regulation of neural precursor cell proliferation GO:2000177 70 0.033
cell division GO:0051301 120 0.033
purine nucleotide metabolic process GO:0006163 302 0.032
pigmentation GO:0043473 71 0.032
wnt signaling pathway GO:0016055 188 0.031
Mouse
embryonic axis specification GO:0000578 30 0.031
morphogenesis of a polarized epithelium GO:0001738 37 0.031
locomotory behavior GO:0007626 195 0.031
mitotic sister chromatid segregation GO:0000070 14 0.030
myofibril assembly GO:0030239 34 0.030
cell substrate adhesion GO:0031589 130 0.030
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.029
regulation of transferase activity GO:0051338 263 0.029
Mouse
regionalization GO:0003002 337 0.029
protein processing GO:0016485 163 0.029
actin filament based movement GO:0030048 23 0.029
actomyosin structure organization GO:0031032 56 0.029
organic anion transport GO:0015711 137 0.028
organelle assembly GO:0070925 177 0.028
developmental maturation GO:0021700 193 0.028
chemotaxis GO:0006935 247 0.028
Mouse Fly
asymmetric protein localization GO:0008105 11 0.028
limb development GO:0060173 166 0.028
negative regulation of wnt signaling pathway GO:0030178 73 0.028
Mouse
synapse organization GO:0050808 125 0.028
formation of primary germ layer GO:0001704 77 0.027
negative regulation of transferase activity GO:0051348 85 0.027
Mouse
neuron projection guidance GO:0097485 141 0.027
Mouse Fly
establishment of spindle localization GO:0051293 19 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.027
cellular ion homeostasis GO:0006873 165 0.027
cell maturation GO:0048469 127 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
Mouse
regulation of cellular component size GO:0032535 121 0.026
apical junction assembly GO:0043297 15 0.026
regulation of blood pressure GO:0008217 93 0.026
Mouse
receptor mediated endocytosis GO:0006898 51 0.025
intracellular protein transport GO:0006886 204 0.025
regulation of exit from mitosis GO:0007096 1 0.025
cellular response to dna damage stimulus GO:0006974 207 0.025
cellularization GO:0007349 1 0.025
mitotic spindle organization GO:0007052 10 0.025
regulation of sister chromatid segregation GO:0033045 13 0.025
cellular amino acid metabolic process GO:0006520 103 0.024
blood vessel morphogenesis GO:0048514 285 0.024
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.024
cellular response to fructose stimulus GO:0071332 2 0.024
pallium development GO:0021543 120 0.023
regulation of mitosis GO:0007088 29 0.023
adult behavior GO:0030534 135 0.023
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 9 0.023
transmembrane transport GO:0055085 412 0.023
protein localization to organelle GO:0033365 185 0.023
protein targeting GO:0006605 143 0.022
digestive tract morphogenesis GO:0048546 147 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
organelle fission GO:0048285 170 0.022
spindle organization GO:0007051 28 0.022
cation transport GO:0006812 399 0.022
sister chromatid segregation GO:0000819 20 0.022
respiratory tube development GO:0030323 167 0.022
mannitol transport GO:0015797 1 0.022
adult locomotory behavior GO:0008344 91 0.022
protein localization to nucleus GO:0034504 121 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.021
cellular response to molecule of bacterial origin GO:0071219 83 0.021
apical protein localization GO:0045176 7 0.020
mapk cascade GO:0000165 281 0.020
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.020
pharynx development GO:0060465 1 0.020
carboxylic acid transport GO:0046942 100 0.020
positive regulation of dipeptide transmembrane transport GO:2001150 2 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
Mouse
vestibular reflex GO:0060005 4 0.019
ribonucleoside monophosphate metabolic process GO:0009161 80 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
lateral line system development GO:0048925 1 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
response to radiation GO:0009314 165 0.019
axon guidance GO:0007411 141 0.018
Mouse Fly
anion transport GO:0006820 177 0.018
spermatid development GO:0007286 108 0.018
anterior posterior axis specification embryo GO:0008595 9 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
receptor internalization GO:0031623 16 0.018
organophosphate catabolic process GO:0046434 232 0.018
phagolysosome assembly GO:0001845 3 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
response to organic cyclic compound GO:0014070 198 0.018
detection of abiotic stimulus GO:0009582 60 0.017
detection of stimulus involved in sensory perception GO:0050906 44 0.017
striated muscle cell development GO:0055002 125 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
negative regulation of immune system process GO:0002683 209 0.017
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.017
cell cell junction assembly GO:0007043 27 0.017
Mouse
cell junction assembly GO:0034329 52 0.017
Mouse
positive regulation of cell development GO:0010720 237 0.017
cellular response to inorganic substance GO:0071241 37 0.017
cytokine production GO:0001816 319 0.017
retina development in camera type eye GO:0060041 119 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
stem cell maintenance GO:0019827 130 0.016
nucleotide metabolic process GO:0009117 332 0.016
cell matrix adhesion GO:0007160 68 0.016
Mouse
photoreceptor cell differentiation GO:0046530 52 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
regulation of mapk cascade GO:0043408 248 0.016
Mouse
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.016
response to inorganic substance GO:0010035 96 0.016
sperm individualization GO:0007291 1 0.016
oogenesis GO:0048477 56 0.016
amide transport GO:0042886 138 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
response to acid chemical GO:0001101 111 0.016
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.016
regulation of transmembrane transport GO:0034762 128 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
response to amino acid GO:0043200 37 0.015
mesoderm morphogenesis GO:0048332 64 0.015
regulation of proteolysis GO:0030162 164 0.015
connective tissue development GO:0061448 179 0.015
eye photoreceptor cell differentiation GO:0001754 41 0.015
alcohol metabolic process GO:0006066 116 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
cell cycle g2 m phase transition GO:0044839 20 0.015
hippocampus development GO:0021766 52 0.015
intracellular ph elevation GO:0051454 3 0.015
calcium ion transmembrane transport GO:0070588 85 0.015
cell cell adhesion GO:0098609 41 0.015
establishment of vesicle localization GO:0051650 81 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
calcium ion homeostasis GO:0055074 127 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
cation transmembrane transport GO:0098655 266 0.015
regulation of systemic arterial blood pressure by atrial natriuretic peptide GO:0003050 2 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
protein maturation GO:0051604 176 0.014
chemosensory behavior GO:0007635 11 0.014
sperm motility GO:0030317 47 0.014
tumor necrosis factor production GO:0032640 50 0.014
female gamete generation GO:0007292 74 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
detection of visible light GO:0009584 14 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
regulation of neuron differentiation GO:0045664 281 0.014
peptide transport GO:0015833 133 0.014
potassium ion transmembrane transport GO:0071805 43 0.014
dna metabolic process GO:0006259 303 0.014
protein oligomerization GO:0051259 67 0.014
b cell activation GO:0042113 161 0.014
regulation of cell motility GO:2000145 236 0.014
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
pilomotor reflex GO:0097195 3 0.014
learning GO:0007612 98 0.014
purine containing compound metabolic process GO:0072521 311 0.014
spermatid differentiation GO:0048515 115 0.014
skeletal system development GO:0001501 356 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of mitotic sister chromatid separation GO:0010965 12 0.013
response to extracellular stimulus GO:0009991 127 0.013
mitochondrion distribution GO:0048311 4 0.013
ras protein signal transduction GO:0007265 77 0.013
exocytosis GO:0006887 121 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
cell growth GO:0016049 130 0.013
cellular amine metabolic process GO:0044106 44 0.013
secondary alcohol metabolic process GO:1902652 3 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
sensory perception of chemical stimulus GO:0007606 51 0.013
stem cell development GO:0048864 219 0.012
neuroblast proliferation GO:0007405 49 0.012
dephosphorylation GO:0016311 129 0.012
Mouse Fly
blastoderm segmentation GO:0007350 13 0.012
regulation of peptidase activity GO:0052547 96 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
purine containing compound catabolic process GO:0072523 213 0.012
angiogenesis GO:0001525 201 0.012
Mouse
gliogenesis GO:0042063 141 0.012
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.012
ameboidal type cell migration GO:0001667 128 0.012
oxidation reduction process GO:0055114 342 0.012
segmentation GO:0035282 93 0.012
amino acid transport GO:0006865 61 0.012
peptidyl lysine modification GO:0018205 77 0.012
epithelial cell proliferation GO:0050673 174 0.012
retinal cone cell development GO:0046549 8 0.012
protein catabolic process GO:0030163 221 0.012
phenol containing compound metabolic process GO:0018958 60 0.012
embryonic appendage morphogenesis GO:0035113 126 0.011
regulation of anatomical structure size GO:0090066 178 0.011
detection of light stimulus GO:0009583 25 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of cellular ketone metabolic process GO:0010565 66 0.011
regulation of systemic arterial blood pressure GO:0003073 61 0.011
Mouse
regulation of cell adhesion GO:0030155 154 0.011
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.011
nucleoside catabolic process GO:0009164 206 0.011
developmental cell growth GO:0048588 84 0.011
reproductive behavior GO:0019098 32 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
smoothened signaling pathway GO:0007224 105 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
atp catabolic process GO:0006200 55 0.011
vesicle organization GO:0016050 60 0.011
photoreceptor cell development GO:0042461 40 0.011
male gamete generation GO:0048232 285 0.011
establishment of endothelial barrier GO:0061028 5 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
blastocyst development GO:0001824 80 0.011
establishment of mitochondrion localization GO:0051654 4 0.011
dicarboxylic acid transport GO:0006835 29 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 9 0.011
embryonic skeletal system development GO:0048706 120 0.011
multi multicellular organism process GO:0044706 109 0.010
regulation of circadian sleep wake cycle GO:0042749 3 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
muscle cell development GO:0055001 133 0.010
stem cell proliferation GO:0072089 117 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
mesoderm development GO:0007498 100 0.010
respiratory system development GO:0060541 190 0.010
Fly
appendage morphogenesis GO:0035107 149 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
establishment of epithelial cell polarity GO:0090162 10 0.010
negative regulation of hydrolase activity GO:0051346 71 0.010
protein modification by small protein conjugation GO:0032446 187 0.010
nucleus organization GO:0006997 45 0.010
detection of light stimulus involved in visual perception GO:0050908 8 0.010

Ptprq disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
auditory system disease DOID:2742 0 0.965
sensory system disease DOID:0050155 0 0.965
disease of anatomical entity DOID:7 0 0.965
nervous system disease DOID:863 0 0.965
autosomal recessive nonsyndromic deafness DOID:0050565 0 0.942
nonsyndromic deafness DOID:0050563 0 0.942
usher syndrome DOID:0050439 0 0.529
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
central nervous system disease DOID:331 0 0.013
cardiovascular system disease DOID:1287 0 0.013
organ system cancer DOID:0050686 0 0.010