Mus musculus

0 known processes

Pttg1ip

pituitary tumor-transforming 1 interacting protein

(Aliases: MGC36923,1810010L20Rik,AU018448,C79540,AI314311)

Pttg1ip biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.182
sphingolipid biosynthetic process GO:0030148 26 0.179
cellular amino acid metabolic process GO:0006520 103 0.157
cellular lipid metabolic process GO:0044255 323 0.127
ceramide metabolic process GO:0006672 31 0.111
membrane lipid biosynthetic process GO:0046467 32 0.100
positive regulation of apoptotic process GO:0043065 217 0.099
amine metabolic process GO:0009308 45 0.097
regulation of apoptotic signaling pathway GO:2001233 197 0.097
apoptotic signaling pathway GO:0097190 306 0.096
cellular ketone metabolic process GO:0042180 84 0.093
positive regulation of apoptotic signaling pathway GO:2001235 95 0.093
endomembrane system organization GO:0010256 147 0.090
cellular amine metabolic process GO:0044106 44 0.090
ceramide biosynthetic process GO:0046513 20 0.077
metal ion homeostasis GO:0055065 189 0.074
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.072
positive regulation of cell death GO:0010942 224 0.068
cellular chemical homeostasis GO:0055082 215 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.064
cellular homeostasis GO:0019725 240 0.063
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.061
response to osmotic stress GO:0006970 21 0.059
membrane organization GO:0061024 245 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.053
positive regulation of programmed cell death GO:0043068 218 0.052
regulation of cellular ketone metabolic process GO:0010565 66 0.050
immune effector process GO:0002252 321 0.049
organonitrogen compound biosynthetic process GO:1901566 192 0.047
regulation of defense response GO:0031347 233 0.046
cellular ion homeostasis GO:0006873 165 0.046
oxidation reduction process GO:0055114 342 0.046
inflammatory response GO:0006954 244 0.043
regulation of protein localization GO:0032880 231 0.042
regulation of secretion GO:0051046 274 0.041
sphingolipid metabolic process GO:0006665 45 0.041
protein localization to membrane GO:0072657 108 0.041
negative regulation of molecular function GO:0044092 258 0.041
organic hydroxy compound metabolic process GO:1901615 203 0.040
cell activation involved in immune response GO:0002263 126 0.040
cation homeostasis GO:0055080 212 0.038
extrinsic apoptotic signaling pathway GO:0097191 126 0.037
protein localization to organelle GO:0033365 185 0.037
lipid biosynthetic process GO:0008610 179 0.037
wnt signaling pathway GO:0016055 188 0.035
regulation of removal of superoxide radicals GO:2000121 4 0.034
homeostasis of number of cells GO:0048872 210 0.034
steroid metabolic process GO:0008202 119 0.034
regulation of membrane potential GO:0042391 192 0.033
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.032
response to light stimulus GO:0009416 135 0.032
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 3 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
negative regulation of cell proliferation GO:0008285 296 0.032
heterocycle catabolic process GO:0046700 280 0.031
cellular metal ion homeostasis GO:0006875 151 0.029
protein catabolic process GO:0030163 221 0.029
cell adhesion GO:0007155 329 0.028
male gamete generation GO:0048232 285 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
regulation of response to wounding GO:1903034 189 0.028
protein processing GO:0016485 163 0.028
lymphocyte differentiation GO:0030098 242 0.027
wound healing GO:0042060 157 0.027
peptidyl amino acid modification GO:0018193 336 0.027
cellular amide metabolic process GO:0043603 58 0.027
regulation of secretion by cell GO:1903530 249 0.026
intracellular protein transport GO:0006886 204 0.026
leukocyte mediated immunity GO:0002443 174 0.026
regulation of protein transport GO:0051223 163 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
hemostasis GO:0007599 78 0.025
organophosphate catabolic process GO:0046434 232 0.025
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.025
cellular response to lipid GO:0071396 145 0.024
positive regulation of fatty acid oxidation GO:0046321 4 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
regulation of peptidase activity GO:0052547 96 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
spermatogenesis GO:0007283 284 0.024
t cell activation GO:0042110 289 0.024
positive regulation of secretion GO:0051047 130 0.024
regulation of hydrolase activity GO:0051336 246 0.024
negative regulation of glycoprotein metabolic process GO:1903019 3 0.024
cytoplasmic transport GO:0016482 234 0.024
ossification GO:0001503 216 0.024
regulation of intracellular transport GO:0032386 159 0.023
retinoid metabolic process GO:0001523 24 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.023
regulation of interleukin 8 production GO:0032677 3 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
muscle tissue development GO:0060537 308 0.023
response to organonitrogen compound GO:0010243 246 0.023
positive regulation of protein modification process GO:0031401 299 0.023
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.023
l ascorbic acid metabolic process GO:0019852 4 0.023
response to organic cyclic compound GO:0014070 198 0.022
golgi vesicle transport GO:0048193 30 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
rho protein signal transduction GO:0007266 32 0.022
membrane lipid metabolic process GO:0006643 53 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
calcium ion homeostasis GO:0055074 127 0.022
positive regulation of endopeptidase activity GO:0010950 43 0.022
regulation of cell cycle GO:0051726 281 0.022
protein ubiquitination GO:0016567 171 0.021
cytokine production GO:0001816 319 0.021
single organism cell adhesion GO:0098602 156 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
regulation of amyloid precursor protein biosynthetic process GO:0042984 3 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
negative regulation of immune system process GO:0002683 209 0.021
regulation of cytokine production GO:0001817 266 0.021
calcium mediated signaling GO:0019722 46 0.021
regulation of multi organism process GO:0043900 111 0.021
cation transport GO:0006812 399 0.021
signal transduction in absence of ligand GO:0038034 55 0.021
regulation of exocytosis GO:0017157 61 0.020
plasma membrane organization GO:0007009 90 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.020
myeloid cell homeostasis GO:0002262 114 0.020
leukocyte differentiation GO:0002521 342 0.020
t cell differentiation GO:0030217 174 0.020
positive regulation of proteolysis GO:0045862 85 0.020
exocytosis GO:0006887 121 0.020
regulation of protein catabolic process GO:0042176 108 0.020
glycerophospholipid metabolic process GO:0006650 71 0.020
mitochondrial calcium ion homeostasis GO:0051560 7 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
regulation of interleukin 8 secretion GO:2000482 2 0.020
response to acid chemical GO:0001101 111 0.020
leukocyte proliferation GO:0070661 172 0.020
regulation of hormone levels GO:0010817 211 0.019
ameboidal type cell migration GO:0001667 128 0.019
ensheathment of neurons GO:0007272 76 0.019
regulation of organelle organization GO:0033043 289 0.019
regulation of endopeptidase activity GO:0052548 89 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
amyloid precursor protein biosynthetic process GO:0042983 3 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.018
action potential GO:0001508 78 0.018
muscle contraction GO:0006936 101 0.018
tissue homeostasis GO:0001894 115 0.018
regulation of proteolysis GO:0030162 164 0.018
defense response to other organism GO:0098542 197 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
cation transmembrane transport GO:0098655 266 0.018
striated muscle tissue development GO:0014706 293 0.018
nucleotide metabolic process GO:0009117 332 0.018
hormone metabolic process GO:0042445 86 0.018
second messenger mediated signaling GO:0019932 73 0.018
cellular response to acid chemical GO:0071229 68 0.018
negative regulation of glycoprotein biosynthetic process GO:0010561 3 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
selenium compound metabolic process GO:0001887 3 0.018
protein localization to nucleus GO:0034504 121 0.018
isoprenoid metabolic process GO:0006720 29 0.017
glycerolipid metabolic process GO:0046486 122 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
mitotic cell cycle GO:0000278 195 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
regulation of cell activation GO:0050865 289 0.017
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
regulation of protein processing GO:0070613 96 0.017
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.017
macromolecule catabolic process GO:0009057 281 0.017
sequestering of metal ion GO:0051238 19 0.017
glycerophospholipid biosynthetic process GO:0046474 32 0.017
protein maturation GO:0051604 176 0.017
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.017
sensory perception GO:0007600 245 0.016
lymphocyte proliferation GO:0046651 164 0.016
multicellular organismal signaling GO:0035637 91 0.016
regulation of leukocyte mediated immunity GO:0002703 104 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
neuromuscular process GO:0050905 99 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
skeletal muscle organ development GO:0060538 163 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
muscle cell differentiation GO:0042692 261 0.016
coagulation GO:0050817 78 0.016
regulation of ossification GO:0030278 112 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
positive regulation of interleukin 8 production GO:0032757 2 0.016
peptidyl tyrosine modification GO:0018212 145 0.015
small molecule biosynthetic process GO:0044283 132 0.015
regulation of homeostatic process GO:0032844 182 0.015
myeloid cell differentiation GO:0030099 233 0.015
response to inorganic substance GO:0010035 96 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.015
single fertilization GO:0007338 82 0.015
cellular protein complex assembly GO:0043623 116 0.015
fat cell differentiation GO:0045444 160 0.015
cell substrate adhesion GO:0031589 130 0.015
regulation of protein stability GO:0031647 52 0.015
blood coagulation GO:0007596 76 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
organelle fusion GO:0048284 28 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
negative regulation of defense response GO:0031348 77 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
dendrite development GO:0016358 115 0.014
regulation of transferase activity GO:0051338 263 0.014
anatomical structure homeostasis GO:0060249 145 0.014
positive regulation of transferase activity GO:0051347 167 0.014
transmission of nerve impulse GO:0019226 76 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
diterpenoid metabolic process GO:0016101 24 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
organism emergence from protective structure GO:0071684 4 0.014
protein localization to plasma membrane GO:0072659 57 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
interleukin 8 production GO:0032637 4 0.014
terpenoid metabolic process GO:0006721 25 0.014
positive regulation of map kinase activity GO:0043406 84 0.014
regulation of inflammatory response GO:0050727 147 0.014
positive regulation of kinase activity GO:0033674 155 0.014
myelination GO:0042552 74 0.014
organelle localization GO:0051640 179 0.014
positive regulation of cytokine production GO:0001819 174 0.014
b cell differentiation GO:0030183 78 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
regulation of cell motility GO:2000145 236 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
mapk cascade GO:0000165 281 0.014
protein secretion GO:0009306 111 0.013
sequestering of calcium ion GO:0051208 18 0.013
nitrogen compound transport GO:0071705 271 0.013
neuronal action potential GO:0019228 54 0.013
membrane tubulation GO:0097320 4 0.013
digestive system development GO:0055123 200 0.013
heart morphogenesis GO:0003007 178 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
response to radiation GO:0009314 165 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
b cell activation GO:0042113 161 0.013
adult behavior GO:0030534 135 0.013
purine containing compound catabolic process GO:0072523 213 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
visual behavior GO:0007632 45 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
vesicle localization GO:0051648 86 0.013
tissue remodeling GO:0048771 102 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
negative regulation of cell motility GO:2000146 61 0.013
fatty acid metabolic process GO:0006631 121 0.013
organic acid biosynthetic process GO:0016053 86 0.013
negative regulation of cell cycle GO:0045786 123 0.013
fat soluble vitamin biosynthetic process GO:0042362 4 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
response to drug GO:0042493 75 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of wound healing GO:0061041 40 0.013
cellular transition metal ion homeostasis GO:0046916 32 0.013
epithelial cell proliferation GO:0050673 174 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
cellular response to superoxide GO:0071451 14 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
response to copper ion GO:0046688 3 0.013
immune response regulating signaling pathway GO:0002764 125 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
respiratory system development GO:0060541 190 0.012
regulation of protein maturation GO:1903317 96 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
divalent inorganic cation transport GO:0072511 178 0.012
chemotaxis GO:0006935 247 0.012
regulation of system process GO:0044057 200 0.012
maintenance of location GO:0051235 89 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
regulation of reproductive process GO:2000241 66 0.012
adaptive immune response GO:0002250 155 0.012
nucleotide catabolic process GO:0009166 217 0.012
negative regulation of cell activation GO:0050866 111 0.012
regulation of cell cycle process GO:0010564 160 0.012
carbohydrate metabolic process GO:0005975 230 0.012
stem cell development GO:0048864 219 0.012
lateral inhibition GO:0046331 1 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
innate immune response GO:0045087 157 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of body fluid levels GO:0050878 162 0.012
digestive tract morphogenesis GO:0048546 147 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
regulation of beta amyloid clearance GO:1900221 1 0.012
divalent metal ion transport GO:0070838 172 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
interleukin 8 secretion GO:0072606 3 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
membrane fusion GO:0061025 38 0.012
regulation of cell migration GO:0030334 219 0.012
ras protein signal transduction GO:0007265 77 0.012
regulation of blood coagulation GO:0030193 28 0.012
synaptic transmission GO:0007268 329 0.012
regulation of neuron death GO:1901214 134 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
blastocyst development GO:0001824 80 0.012
regulation of voltage gated calcium channel activity GO:1901385 4 0.012
maintenance of apical basal cell polarity GO:0035090 3 0.012
cell type specific apoptotic process GO:0097285 268 0.012
positive regulation of cell motility GO:2000147 116 0.012
regulation of cell adhesion GO:0030155 154 0.012
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.012
positive regulation of organelle organization GO:0010638 128 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
organic cyclic compound catabolic process GO:1901361 295 0.011
progesterone metabolic process GO:0042448 4 0.011
peptide metabolic process GO:0006518 46 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
mitotic cytokinesis GO:0000281 4 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
neuron death GO:0070997 154 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
negative regulation of inflammatory response GO:0050728 61 0.011
muscle system process GO:0003012 141 0.011
mitotic cell cycle process GO:1903047 159 0.011
visual learning GO:0008542 44 0.011
cellular protein catabolic process GO:0044257 155 0.011
negative regulation of proteolysis GO:0045861 74 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
regulation of fatty acid beta oxidation GO:0031998 1 0.011
l ascorbic acid biosynthetic process GO:0019853 3 0.011
regulation of mapk cascade GO:0043408 248 0.011
amino acid betaine metabolic process GO:0006577 7 0.011
glucose homeostasis GO:0042593 128 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
cell growth GO:0016049 130 0.011
cell cell junction organization GO:0045216 72 0.011
transition metal ion homeostasis GO:0055076 54 0.011
transmembrane transport GO:0055085 412 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
negative regulation of response to wounding GO:1903035 77 0.011
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
fertilization GO:0009566 127 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
hatching GO:0035188 4 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
glycolipid metabolic process GO:0006664 25 0.011
biomineral tissue development GO:0031214 64 0.011
positive regulation of interleukin 8 secretion GO:2000484 1 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
regulation of neuron projection development GO:0010975 169 0.011
lipid modification GO:0030258 65 0.011
locomotory behavior GO:0007626 195 0.011
neuromuscular process controlling balance GO:0050885 59 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
nuclear transport GO:0051169 139 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
microglia development GO:0014005 2 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
microglia differentiation GO:0014004 2 0.010
extracellular structure organization GO:0043062 148 0.010
regulation of anatomical structure size GO:0090066 178 0.010
microtubule based process GO:0007017 236 0.010
glycerolipid biosynthetic process GO:0045017 50 0.010
positive regulation of peptidase activity GO:0010952 49 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
cofactor metabolic process GO:0051186 80 0.010
natural killer cell degranulation GO:0043320 3 0.010
norepinephrine secretion GO:0048243 2 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
response to growth factor GO:0070848 198 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010

Pttg1ip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.326
inherited metabolic disorder DOID:655 0 0.167
sensory system disease DOID:0050155 0 0.078
disease of anatomical entity DOID:7 0 0.078
eye and adnexa disease DOID:1492 0 0.078
nervous system disease DOID:863 0 0.078
eye disease DOID:5614 0 0.078
lysosomal storage disease DOID:3211 0 0.047
immune system disease DOID:2914 0 0.039
retinal disease DOID:5679 0 0.036
retinal degeneration DOID:8466 0 0.036
hematopoietic system disease DOID:74 0 0.031
acquired metabolic disease DOID:0060158 0 0.023
primary immunodeficiency disease DOID:612 0 0.016
neuropathy DOID:870 0 0.013
neuromuscular disease DOID:440 0 0.013
charcot marie tooth disease DOID:10595 0 0.013
lipid storage disease DOID:9455 0 0.012
sphingolipidosis DOID:1927 0 0.012
amyloidosis DOID:9120 0 0.012