|
|
pyroptosis
|
GO:0070269 |
8 |
0.994
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.992
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.985
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
10 |
0.984
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.968
|
|
|
|
interleukin 18 production
|
GO:0032621 |
4 |
0.935
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.935
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.932
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.931
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.929
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.922
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.918
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.918
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.913
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
14 |
0.907
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.901
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.885
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.883
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.872
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.860
|
|
|
|
regulation of prostaglandin endoperoxide synthase activity
|
GO:0060584 |
2 |
0.848
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.838
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.833
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.822
|
|
|
|
cellular response to interferon beta
|
GO:0035458 |
21 |
0.817
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.814
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.811
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.803
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.797
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
15 |
0.795
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
16 |
0.794
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.790
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.789
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.788
|
|
|
|
positive regulation of interleukin 1 alpha secretion
|
GO:0050717 |
3 |
0.778
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.773
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.757
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.755
|
|
|
|
regulation of interleukin 1 alpha secretion
|
GO:0050705 |
3 |
0.755
|
|
|
|
regulation of apoptotic dna fragmentation
|
GO:1902510 |
5 |
0.754
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.742
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.739
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.729
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.724
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.718
|
|
|
|
regulation of circadian sleep wake cycle non rem sleep
|
GO:0045188 |
1 |
0.713
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.711
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.703
|
Human |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.694
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.690
|
|
|
|
positive regulation of interleukin 1 alpha production
|
GO:0032730 |
4 |
0.685
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.681
|
Human |
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
9 |
0.680
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.679
|
Human |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.670
|
Human |
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.666
|
|
|
|
helper t cell enhancement of adaptive immune response
|
GO:0035397 |
1 |
0.663
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.650
|
|
|
|
circadian sleep wake cycle non rem sleep
|
GO:0042748 |
2 |
0.637
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.636
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.636
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.632
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.625
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.620
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.616
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.605
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.594
|
Human |
|
|
autophagy
|
GO:0006914 |
45 |
0.586
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.586
|
Human |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.558
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.546
|
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.524
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
3 |
0.524
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.514
|
Human |
|
|
protein secretion
|
GO:0009306 |
111 |
0.508
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.505
|
|
|
|
interleukin 1 alpha secretion
|
GO:0050703 |
3 |
0.491
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
21 |
0.489
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
19 |
0.487
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.485
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
7 |
0.480
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.473
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.471
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.458
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
9 |
0.456
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.438
|
Human |
|
|
regulation of interleukin 18 production
|
GO:0032661 |
3 |
0.435
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
25 |
0.431
|
|
|
|
hepatocyte apoptotic process
|
GO:0097284 |
11 |
0.428
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.427
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.422
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.417
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.416
|
Human |
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.413
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.409
|
Human |
|
|
zymogen activation
|
GO:0031638 |
41 |
0.406
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.400
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.397
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.391
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.385
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.376
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.376
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.371
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.369
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.369
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.361
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.352
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.352
|
|
|
|
response to atp
|
GO:0033198 |
8 |
0.352
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.351
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.351
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.346
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.342
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.340
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.331
|
Human |
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.330
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.323
|
|
|
|
response to interferon beta
|
GO:0035456 |
22 |
0.318
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.314
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.311
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
9 |
0.308
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.304
|
|
|
|
regulation of interleukin 1 alpha production
|
GO:0032650 |
4 |
0.302
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.291
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.289
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.287
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.287
|
|
|
|
regulation of dna catabolic process
|
GO:1903624 |
5 |
0.287
|
|
|
|
positive regulation of interleukin 1 production
|
GO:0032732 |
17 |
0.282
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.280
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.279
|
Human |
|
|
endocytosis
|
GO:0006897 |
168 |
0.273
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.272
|
Human |
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.267
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.263
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.263
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.262
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.260
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.252
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.251
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.245
|
|
|
|
melanin metabolic process
|
GO:0006582 |
12 |
0.242
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.239
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
19 |
0.239
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.237
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.225
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.222
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.221
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.221
|
|
|
|
innate immune response in mucosa
|
GO:0002227 |
3 |
0.220
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.219
|
Human |
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.218
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.216
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.215
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.210
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.209
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.207
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.199
|
|
|
|
toxin transport
|
GO:1901998 |
38 |
0.198
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.198
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.198
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.197
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.195
|
Human |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.194
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.193
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
27 |
0.192
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.192
|
|
|
|
protein autoprocessing
|
GO:0016540 |
2 |
0.190
|
|
|
|
pigment metabolic process
|
GO:0042440 |
32 |
0.189
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.186
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
23 |
0.186
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.183
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.183
|
|
|
|
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria
|
GO:0006965 |
1 |
0.181
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.181
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.179
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.179
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.177
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.174
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
19 |
0.174
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.169
|
Human |
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.169
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.168
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.168
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
6 |
0.167
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.166
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.163
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.162
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.161
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.161
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.160
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.160
|
Human |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.160
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.159
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.157
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.157
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.157
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.156
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.154
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.152
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.152
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.150
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.148
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.146
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.146
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.145
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.145
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.144
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.143
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.143
|
Human |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.141
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
5 |
0.140
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.139
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.139
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.137
|
Human |
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.136
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.132
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.132
|
Human |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.131
|
|
|
|
positive regulation of antibacterial peptide production
|
GO:0002803 |
1 |
0.130
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.130
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.128
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.127
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.127
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.127
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.127
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.126
|
Human |
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.126
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.124
|
Human |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.122
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.122
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.119
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.118
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.118
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.118
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.118
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.118
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.117
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.117
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.116
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.116
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.115
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.114
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.112
|
|
|
|
negative regulation of activated t cell proliferation
|
GO:0046007 |
7 |
0.112
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.111
|
|
|
|
negative regulation of interleukin 18 production
|
GO:0032701 |
1 |
0.110
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.110
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.109
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.108
|
|
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
21 |
0.108
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.107
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.106
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.105
|
Human |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.104
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
17 |
0.103
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.103
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.102
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.102
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.102
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.102
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.100
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.100
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.099
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.098
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.098
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.097
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.096
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.095
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.095
|
|
|
|
regulation of interferon alpha production
|
GO:0032647 |
5 |
0.095
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.094
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.094
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.093
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
29 |
0.093
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.093
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.093
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.092
|
|
|
|
memory
|
GO:0007613 |
58 |
0.091
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.089
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.088
|
|
|
|
mitochondrial depolarization
|
GO:0051882 |
6 |
0.088
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.088
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.088
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.087
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.087
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.087
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
18 |
0.086
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.086
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
20 |
0.086
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.086
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.085
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.085
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.085
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.084
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.084
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.083
|
Human |
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.082
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
14 |
0.081
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.081
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
17 |
0.081
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.080
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.080
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.080
|
Human |
|
|
b cell activation
|
GO:0042113 |
161 |
0.079
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.079
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.079
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
15 |
0.079
|
Human |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.079
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.078
|
|
|
|
interleukin 10 production
|
GO:0032613 |
23 |
0.078
|
Human |
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.077
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.077
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
9 |
0.077
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.076
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.076
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.074
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.074
|
Human |
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.073
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.073
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.073
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.073
|
|
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
28 |
0.073
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.073
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.072
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.071
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.071
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.070
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.070
|
|
|
|
mucosal immune response
|
GO:0002385 |
13 |
0.069
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.068
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.068
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.068
|
|
|
|
regulation of isomerase activity
|
GO:0010911 |
1 |
0.068
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.068
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.067
|
Human |
|
|
response to organophosphorus
|
GO:0046683 |
22 |
0.066
|
|
|
|
adhesion of symbiont to host
|
GO:0044406 |
8 |
0.066
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.066
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.066
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.066
|
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
7 |
0.066
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.065
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
10 |
0.065
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.065
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.065
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.065
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.064
|
|
|
|
dna catabolic process
|
GO:0006308 |
19 |
0.063
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.063
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.062
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.062
|
|
|
|
nlrp3 inflammasome complex assembly
|
GO:0044546 |
5 |
0.062
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.061
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.061
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.061
|
|
|
|
regulation of t helper 17 type immune response
|
GO:2000316 |
4 |
0.061
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.061
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.061
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.061
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.060
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.060
|
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
6 |
0.060
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.059
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.059
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.059
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.058
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.058
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.057
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.057
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.057
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.057
|
|
|
|
regulation of mucus secretion
|
GO:0070255 |
11 |
0.057
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.056
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.056
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.055
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.055
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.054
|
|
|
|
response to dexamethasone
|
GO:0071548 |
8 |
0.053
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.051
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.051
|
|
|
|
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria
|
GO:0002816 |
1 |
0.051
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.051
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.050
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.050
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.050
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.050
|
|
|
|
positive regulation of prostaglandin endoperoxide synthase activity
|
GO:0060585 |
2 |
0.050
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.049
|
Human |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.049
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.049
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.049
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.049
|
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
10 |
0.048
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.048
|
|
|
|
defense response to fungus
|
GO:0050832 |
12 |
0.048
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.048
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.048
|
Human |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.048
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.048
|
|
|
|
regulation of dendritic cell antigen processing and presentation
|
GO:0002604 |
7 |
0.048
|
|
|
|
response to purine containing compound
|
GO:0014074 |
28 |
0.047
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
8 |
0.047
|
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
15 |
0.047
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.047
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
6 |
0.047
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.046
|
Human |
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.046
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.045
|
Human |
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.045
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.044
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.044
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.044
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.044
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.043
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.043
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.043
|
|
|
|
interferon alpha production
|
GO:0032607 |
7 |
0.043
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.042
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
25 |
0.042
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.042
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.042
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.041
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.041
|
|
|
|
mucus secretion
|
GO:0070254 |
12 |
0.041
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.041
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.040
|
Human |
|
|
dendrite development
|
GO:0016358 |
115 |
0.040
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.040
|
|
|
|
biosynthetic process of antibacterial peptides active against gram positive bacteria
|
GO:0002815 |
1 |
0.040
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.039
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.039
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.038
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.038
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.038
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.038
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.038
|
Human |
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.037
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.037
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.037
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.037
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.037
|
|
|
|
regulation of prostaglandin e synthase activity
|
GO:2000361 |
1 |
0.036
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.036
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.036
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.036
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.036
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.035
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.035
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.035
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.035
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.034
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.034
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.034
|
Human |
|
|
anion transport
|
GO:0006820 |
177 |
0.033
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.033
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.033
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.032
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.032
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.032
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.032
|
Human |
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.032
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
26 |
0.032
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.032
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.032
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
13 |
0.031
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.031
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.031
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.031
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.030
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.030
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.030
|
Human |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.030
|
Human |
|
|
positive regulation of prostaglandin e synthase activity
|
GO:2000363 |
1 |
0.030
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.030
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.030
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.029
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.029
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.029
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.029
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.029
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.029
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.029
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
17 |
0.029
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.029
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.029
|
Human |
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.029
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.029
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.029
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.028
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.028
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.028
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.028
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.028
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.028
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.028
|
|
