Mus musculus

0 known processes

Qdpr

quinoid dihydropteridine reductase

(Aliases: PKU2,Dhpr,D5Ertd371e,2610008L04Rik)

Qdpr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.646
Human Rat
cellular amino acid metabolic process GO:0006520 103 0.431
Rat
small molecule catabolic process GO:0044282 71 0.412
Rat
aldehyde catabolic process GO:0046185 4 0.386
monocarboxylic acid metabolic process GO:0032787 191 0.304
cellular aldehyde metabolic process GO:0006081 12 0.217
small molecule biosynthetic process GO:0044283 132 0.190
cellular modified amino acid metabolic process GO:0006575 63 0.179
organic hydroxy compound metabolic process GO:1901615 203 0.173
cellular ketone metabolic process GO:0042180 84 0.171
ketone catabolic process GO:0042182 3 0.156
carboxylic acid biosynthetic process GO:0046394 86 0.138
regulation of cellular amino acid metabolic process GO:0006521 5 0.104
amine metabolic process GO:0009308 45 0.102
cellular lipid metabolic process GO:0044255 323 0.100
alpha amino acid metabolic process GO:1901605 59 0.096
Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.095
cellular amine metabolic process GO:0044106 44 0.095
sulfur compound metabolic process GO:0006790 100 0.084
cellular amino acid biosynthetic process GO:0008652 22 0.082
regulation of cellular amine metabolic process GO:0033238 20 0.081
steroid metabolic process GO:0008202 119 0.081
carboxylic acid catabolic process GO:0046395 51 0.080
Rat
alcohol metabolic process GO:0006066 116 0.078
alpha amino acid biosynthetic process GO:1901607 15 0.074
coenzyme metabolic process GO:0006732 52 0.073
Rat
generation of precursor metabolites and energy GO:0006091 103 0.065
energy derivation by oxidation of organic compounds GO:0015980 77 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.064
positive regulation of cellular amine metabolic process GO:0033240 5 0.062
lipid biosynthetic process GO:0008610 179 0.060
positive regulation of protein modification process GO:0031401 299 0.058
organic acid biosynthetic process GO:0016053 86 0.057
glycosyl compound metabolic process GO:1901657 246 0.055
heterocycle catabolic process GO:0046700 280 0.054
nucleotide metabolic process GO:0009117 332 0.053
purine ribonucleotide metabolic process GO:0009150 290 0.050
cellular respiration GO:0045333 38 0.049
peptidyl amino acid modification GO:0018193 336 0.049
renal system development GO:0072001 225 0.047
nucleoside metabolic process GO:0009116 246 0.046
organonitrogen compound catabolic process GO:1901565 264 0.046
Rat
alcohol biosynthetic process GO:0046165 43 0.045
organonitrogen compound biosynthetic process GO:1901566 192 0.044
Rat
reactive oxygen species metabolic process GO:0072593 84 0.043
transmembrane transport GO:0055085 412 0.043
regulation of apoptotic signaling pathway GO:2001233 197 0.042
fatty acid metabolic process GO:0006631 121 0.042
organic acid catabolic process GO:0016054 51 0.042
Rat
interleukin 8 production GO:0032637 4 0.040
cellular modified amino acid biosynthetic process GO:0042398 12 0.039
ribonucleotide metabolic process GO:0009259 291 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.037
regulation of protein kinase activity GO:0045859 232 0.037
aromatic compound catabolic process GO:0019439 286 0.036
Rat
kidney development GO:0001822 213 0.036
cellular alcohol metabolic process GO:0044107 3 0.035
response to organic cyclic compound GO:0014070 198 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
hormone metabolic process GO:0042445 86 0.033
response to oxygen radical GO:0000305 16 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
negative regulation of protein metabolic process GO:0051248 282 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
Rat
spermatogenesis GO:0007283 284 0.032
response to molecule of bacterial origin GO:0002237 143 0.032
ribonucleoside metabolic process GO:0009119 245 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
nitrogen compound transport GO:0071705 271 0.031
positive regulation of cellular respiration GO:1901857 3 0.031
apoptotic signaling pathway GO:0097190 306 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
response to testosterone GO:0033574 3 0.030
hepaticobiliary system development GO:0061008 67 0.029
Rat
gland development GO:0048732 330 0.029
Rat
purine ribonucleoside catabolic process GO:0046130 205 0.029
reactive oxygen species biosynthetic process GO:1903409 8 0.029
urogenital system development GO:0001655 261 0.028
regulation of cytokine production GO:0001817 266 0.028
regulation of reactive oxygen species metabolic process GO:2000377 40 0.028
monocarboxylic acid biosynthetic process GO:0072330 61 0.028
mapk cascade GO:0000165 281 0.028
catecholamine uptake GO:0090493 4 0.028
cellular response to oxygen radical GO:0071450 14 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
coenzyme biosynthetic process GO:0009108 23 0.027
Rat
cellular response to oxidative stress GO:0034599 76 0.027
organophosphate catabolic process GO:0046434 232 0.027
male gamete generation GO:0048232 285 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
intracellular protein transport GO:0006886 204 0.026
liver development GO:0001889 66 0.026
Rat
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.026
response to organonitrogen compound GO:0010243 246 0.026
Rat
regulation of hormone levels GO:0010817 211 0.026
myeloid cell differentiation GO:0030099 233 0.025
regulation of protein localization GO:0032880 231 0.025
purine containing compound metabolic process GO:0072521 311 0.025
cell type specific apoptotic process GO:0097285 268 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
negative regulation of immune system process GO:0002683 209 0.024
peptide metabolic process GO:0006518 46 0.024
response to lipopolysaccharide GO:0032496 128 0.024
positive regulation of cell death GO:0010942 224 0.024
regulation of kinase activity GO:0043549 249 0.024
organic hydroxy compound biosynthetic process GO:1901617 77 0.024
regulation of membrane potential GO:0042391 192 0.024
neuron apoptotic process GO:0051402 142 0.024
thioester metabolic process GO:0035383 19 0.023
glutathione metabolic process GO:0006749 16 0.023
cytoplasmic transport GO:0016482 234 0.023
regulation of interleukin 8 production GO:0032677 3 0.022
positive regulation of apoptotic signaling pathway GO:2001235 95 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
homeostasis of number of cells GO:0048872 210 0.022
regulation of mapk cascade GO:0043408 248 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
regulation of peptide transport GO:0090087 91 0.022
response to extracellular stimulus GO:0009991 127 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
transmission of nerve impulse GO:0019226 76 0.021
peptidyl serine modification GO:0018209 83 0.021
cytokine production GO:0001816 319 0.021
cofactor metabolic process GO:0051186 80 0.021
Rat
response to steroid hormone GO:0048545 56 0.021
neuronal action potential GO:0019228 54 0.021
protein localization to organelle GO:0033365 185 0.021
regulation of transmembrane transport GO:0034762 128 0.021
leukocyte differentiation GO:0002521 342 0.021
positive regulation of interleukin 8 production GO:0032757 2 0.020
cofactor biosynthetic process GO:0051188 41 0.020
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
macromolecule catabolic process GO:0009057 281 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
rhythmic process GO:0048511 174 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
regulation of transferase activity GO:0051338 263 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
cellular amide metabolic process GO:0043603 58 0.019
response to oxidative stress GO:0006979 123 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
purine containing compound catabolic process GO:0072523 213 0.019
cellular homeostasis GO:0019725 240 0.019
acyl coa metabolic process GO:0006637 19 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
skin development GO:0043588 220 0.019
cellular response to lipid GO:0071396 145 0.019
regulation of cellular response to stress GO:0080135 159 0.019
maintenance of location GO:0051235 89 0.019
response to nutrient levels GO:0031667 109 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
multicellular organism growth GO:0035264 161 0.018
regulation of neurotransmitter levels GO:0001505 87 0.018
synaptic transmission GO:0007268 329 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
sterol metabolic process GO:0016125 58 0.018
negative regulation of molecular function GO:0044092 258 0.018
glucose metabolic process GO:0006006 92 0.018
cellular alcohol biosynthetic process GO:0044108 3 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
steroid biosynthetic process GO:0006694 47 0.017
negative regulation of protein modification process GO:0031400 163 0.017
nucleotide catabolic process GO:0009166 217 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
microtubule based process GO:0007017 236 0.017
regulation of response to wounding GO:1903034 189 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
regulation of organelle organization GO:0033043 289 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.017
inflammatory response GO:0006954 244 0.017
gonad development GO:0008406 141 0.017
ossification GO:0001503 216 0.017
regulation of protein transport GO:0051223 163 0.017
regulation of map kinase activity GO:0043405 120 0.016
bone development GO:0060348 120 0.016
regulation of ion transport GO:0043269 215 0.016
dephosphorylation GO:0016311 129 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
nuclear transport GO:0051169 139 0.016
regulation of neuron death GO:1901214 134 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
protein oxidation GO:0018158 2 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
response to starvation GO:0042594 65 0.016
action potential GO:0001508 78 0.016
primary alcohol metabolic process GO:0034308 11 0.016
placenta development GO:0001890 140 0.015
regulation of transporter activity GO:0032409 57 0.015
removal of superoxide radicals GO:0019430 12 0.015
adult behavior GO:0030534 135 0.015
cation transport GO:0006812 399 0.015
regulation of androgen receptor signaling pathway GO:0060765 3 0.015
chromatin modification GO:0016568 187 0.015
regulation of secretion GO:0051046 274 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
histone modification GO:0016570 159 0.015
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.015
tricarboxylic acid metabolic process GO:0072350 5 0.015
nucleoside catabolic process GO:0009164 206 0.015
locomotory behavior GO:0007626 195 0.015
regulation of secretion by cell GO:1903530 249 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
ion transmembrane transport GO:0034220 361 0.014
response to superoxide GO:0000303 16 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
regulation of nucleocytoplasmic transport GO:0046822 73 0.014
lipid localization GO:0010876 126 0.014
monosaccharide metabolic process GO:0005996 106 0.014
tissue homeostasis GO:0001894 115 0.014
positive regulation of growth GO:0045927 104 0.014
regulation of cell activation GO:0050865 289 0.014
regulation of removal of superoxide radicals GO:2000121 4 0.014
protein import GO:0017038 101 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
fat cell differentiation GO:0045444 160 0.014
dopamine uptake GO:0090494 4 0.014
citrate metabolic process GO:0006101 3 0.014
phenol containing compound metabolic process GO:0018958 60 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
response to drug GO:0042493 75 0.013
Rat
purine nucleotide catabolic process GO:0006195 211 0.013
male sex differentiation GO:0046661 109 0.013
negative regulation of kinase activity GO:0033673 81 0.013
negative regulation of transferase activity GO:0051348 85 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
regulation of protein catabolic process GO:0042176 108 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
response to acid chemical GO:0001101 111 0.013
sensory perception GO:0007600 245 0.013
regulation of defense response GO:0031347 233 0.013
chromatin organization GO:0006325 206 0.013
neuron migration GO:0001764 122 0.013
regulation of proteolysis GO:0030162 164 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
cellular response to organic cyclic compound GO:0071407 87 0.012
proton transport GO:0015992 35 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
dopamine metabolic process GO:0042417 23 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
covalent chromatin modification GO:0016569 163 0.012
bone morphogenesis GO:0060349 78 0.012
response to reactive oxygen species GO:0000302 56 0.012
monoamine transport GO:0015844 33 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
immune effector process GO:0002252 321 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
skeletal system development GO:0001501 356 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
kidney epithelium development GO:0072073 121 0.012
peptidyl lysine modification GO:0018205 77 0.012
positive regulation of transferase activity GO:0051347 167 0.012
regulation of protein binding GO:0043393 60 0.012
lung development GO:0030324 164 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
neuron death GO:0070997 154 0.012
positive regulation of kinase activity GO:0033674 155 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cation transmembrane transport GO:0098655 266 0.012
protein ubiquitination GO:0016567 171 0.011
innate immune response GO:0045087 157 0.011
amide transport GO:0042886 138 0.011
positive regulation of cytokine production GO:0001819 174 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
response to oxygen levels GO:0070482 62 0.011
negative regulation of peptidase activity GO:0010466 46 0.011
cellular chemical homeostasis GO:0055082 215 0.011
coenzyme a metabolic process GO:0015936 8 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.011
carbohydrate metabolic process GO:0005975 230 0.011
striated muscle tissue development GO:0014706 293 0.011
development of primary sexual characteristics GO:0045137 143 0.011
skeletal system morphogenesis GO:0048705 203 0.011
epithelial cell development GO:0002064 159 0.011
branched chain amino acid catabolic process GO:0009083 2 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
protein tetramerization GO:0051262 23 0.011
cellular amino acid catabolic process GO:0009063 25 0.011
Rat
cellular response to extracellular stimulus GO:0031668 81 0.011
positive regulation of cell development GO:0010720 237 0.011
positive regulation of map kinase activity GO:0043406 84 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
camera type eye development GO:0043010 266 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
establishment of protein localization to peroxisome GO:0072663 4 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
hydrogen peroxide metabolic process GO:0042743 16 0.011
protein targeting GO:0006605 143 0.010
neuron neuron synaptic transmission GO:0007270 69 0.010
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.010
atp metabolic process GO:0046034 75 0.010
learning or memory GO:0007611 148 0.010
cellular response to superoxide GO:0071451 14 0.010
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.010
cellular protein catabolic process GO:0044257 155 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
negative regulation of neuron death GO:1901215 98 0.010
cofactor transport GO:0051181 4 0.010
respiratory system development GO:0060541 190 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
cognition GO:0050890 149 0.010
regulation of generation of precursor metabolites and energy GO:0043467 38 0.010

Qdpr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.369
inherited metabolic disorder DOID:655 0 0.220
amino acid metabolic disorder DOID:9252 0 0.085
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
neurodegenerative disease DOID:1289 0 0.024
central nervous system disease DOID:331 0 0.024
disease of cellular proliferation DOID:14566 0 0.023
cancer DOID:162 0 0.023
organic acidemia DOID:0060159 0 0.015