Mus musculus

349 known processes

Rac1

RAS-related C3 botulinum substrate 1

(Aliases: D5Ertd559e,AL023026)

Rac1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
exocyst localization GO:0051601 2 0.999
actin filament organization GO:0007015 113 0.998
regulation of actin cytoskeleton organization GO:0032956 84 0.997
response to osmotic stress GO:0006970 21 0.997
regulation of actin filament length GO:0030832 45 0.996
vacuole organization GO:0007033 38 0.995
activation of mapkkk activity GO:0000185 1 0.995
regulation of vacuole organization GO:0044088 4 0.993
regulation of actin filament polymerization GO:0030833 38 0.992
jnk cascade GO:0007254 72 0.991
Fly
asymmetric neuroblast division GO:0055059 1 0.989
regulation of actin filament bundle assembly GO:0032231 18 0.986
Human
membrane organization GO:0061024 245 0.985
negative regulation of actin filament depolymerization GO:0030835 9 0.984
apical junction assembly GO:0043297 15 0.984
guanosine containing compound metabolic process GO:1901068 144 0.981
actin filament bundle assembly GO:0051017 40 0.981
Human Mouse Fly
guanosine containing compound catabolic process GO:1901069 144 0.980
cell cell junction organization GO:0045216 72 0.978
actin cytoskeleton organization GO:0030036 220 0.977
regulation of actin filament based process GO:0032970 99 0.977
ribonucleoside metabolic process GO:0009119 245 0.976
regulation of exocyst localization GO:0060178 2 0.975
actin filament polymerization GO:0030041 44 0.972
ras protein signal transduction GO:0007265 77 0.970
Mouse Fly
organonitrogen compound catabolic process GO:1901565 264 0.968
barbed end actin filament capping GO:0051016 6 0.968
cellular component assembly involved in morphogenesis GO:0010927 139 0.966
Fly
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.962
actomyosin structure organization GO:0031032 56 0.961
Human
regulation of protein kinase activity GO:0045859 232 0.961
Mouse Fly
regulation of gtp catabolic process GO:0033124 113 0.960
regulation of transferase activity GO:0051338 263 0.959
purine containing compound metabolic process GO:0072521 311 0.956
positive regulation of actin filament bundle assembly GO:0032233 11 0.954
Human
regulation of cytoskeleton organization GO:0051493 122 0.951
neuron projection guidance GO:0097485 141 0.948
cytokinesis GO:0000910 17 0.947
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.945
Mouse
cell junction assembly GO:0034329 52 0.944
Human
nucleotide metabolic process GO:0009117 332 0.941
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.941
ribonucleoside triphosphate catabolic process GO:0009203 199 0.935
regulation of cell cycle process GO:0010564 160 0.935
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.934
cellular nitrogen compound catabolic process GO:0044270 280 0.934
heterocycle catabolic process GO:0046700 280 0.933
microtubule based process GO:0007017 236 0.932
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.932
regulation of cell cycle GO:0051726 281 0.932
Mouse Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.931
nucleoside metabolic process GO:0009116 246 0.930
gtp catabolic process GO:0006184 143 0.929
microtubule cytoskeleton organization GO:0000226 157 0.927
Fly
regulation of ras gtpase activity GO:0032318 88 0.927
nucleoside catabolic process GO:0009164 206 0.927
protein kinase c signaling GO:0070528 7 0.926
positive regulation of actin filament polymerization GO:0030838 26 0.921
regulation of lamellipodium assembly GO:0010591 3 0.920
Human Mouse Fly
positive regulation of gtp catabolic process GO:0033126 85 0.919
synapse organization GO:0050808 125 0.919
Fly
sterol transmembrane transport GO:0035382 2 0.919
regulation of cellular component biogenesis GO:0044087 181 0.918
regulation of exit from mitosis GO:0007096 1 0.917
positive regulation of ras gtpase activity GO:0032320 65 0.917
regulation of synapse structural plasticity GO:0051823 4 0.917
regulation of actin polymerization or depolymerization GO:0008064 45 0.916
axon guidance GO:0007411 141 0.916
regulation of cell division GO:0051302 76 0.913
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.912
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.912
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.912
Fly
rho protein signal transduction GO:0007266 32 0.907
Mouse Fly
positive regulation of protein phosphorylation GO:0001934 242 0.904
Human Mouse Fly
purine containing compound catabolic process GO:0072523 213 0.903
purine ribonucleoside metabolic process GO:0046128 241 0.901
substantia nigra development GO:0021762 2 0.900
positive regulation of protein kinase activity GO:0045860 144 0.900
Fly
ribonucleotide catabolic process GO:0009261 208 0.898
organelle fusion GO:0048284 28 0.896
nucleobase containing small molecule metabolic process GO:0055086 352 0.896
sensory perception of touch GO:0050975 2 0.894
Fly
regulation of cell motility GO:2000145 236 0.894
nucleoside phosphate metabolic process GO:0006753 338 0.892
positive regulation of rac gtpase activity GO:0032855 14 0.887
synaptic growth at neuromuscular junction GO:0051124 6 0.887
membrane fusion GO:0061025 38 0.886
glycosyl compound catabolic process GO:1901658 206 0.884
cytoskeleton dependent intracellular transport GO:0030705 50 0.883
regulation of purine nucleotide catabolic process GO:0033121 122 0.881
ribonucleoside catabolic process GO:0042454 206 0.879
carbohydrate derivative catabolic process GO:1901136 231 0.879
purine ribonucleotide metabolic process GO:0009150 290 0.875
purine ribonucleotide catabolic process GO:0009154 208 0.871
positive regulation of metalloenzyme activity GO:0048554 3 0.869
regulation of nucleoside metabolic process GO:0009118 130 0.865
nucleoside phosphate catabolic process GO:1901292 222 0.861
microtubule based movement GO:0007018 84 0.860
pigment metabolic process GO:0042440 32 0.860
Fly
engulfment of apoptotic cell GO:0043652 3 0.856
regulation of ras protein signal transduction GO:0046578 114 0.852
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.850
Fly
small gtpase mediated signal transduction GO:0007264 97 0.848
positive regulation of endocytosis GO:0045807 42 0.846
gtp metabolic process GO:0046039 144 0.842
secondary metabolic process GO:0019748 18 0.842
Fly
positive regulation of cellular catabolic process GO:0031331 148 0.841
cleavage furrow formation GO:0036089 2 0.832
regulation of protein localization GO:0032880 231 0.832
ribonucleotide metabolic process GO:0009259 291 0.830
cell junction organization GO:0034330 77 0.828
forebrain generation of neurons GO:0021872 63 0.827
cell division GO:0051301 120 0.827
Mouse
regulation of actin filament depolymerization GO:0030834 13 0.827
purine nucleoside catabolic process GO:0006152 205 0.824
canonical wnt signaling pathway GO:0060070 130 0.823
Mouse
cell cell junction assembly GO:0007043 27 0.821
positive regulation of cytoskeleton organization GO:0051495 49 0.821
positive regulation of protein modification process GO:0031401 299 0.820
Human Mouse Fly
protein polymerization GO:0051258 57 0.818
dendrite development GO:0016358 115 0.815
circulatory system process GO:0003013 197 0.814
Mouse
purine nucleotide catabolic process GO:0006195 211 0.807
regulation of protein depolymerization GO:1901879 26 0.804
neuromuscular process controlling balance GO:0050885 59 0.804
Mouse
glycosyl compound metabolic process GO:1901657 246 0.804
regulation of tight junction assembly GO:2000810 2 0.803
innate immune response GO:0045087 157 0.801
Fly
regulation of protein complex assembly GO:0043254 83 0.797
cation transport GO:0006812 399 0.795
regulation of hydrolase activity GO:0051336 246 0.791
peptidyl amino acid modification GO:0018193 336 0.785
Mouse
regulation of cell migration GO:0030334 219 0.782
mitotic cell cycle process GO:1903047 159 0.782
Mouse
regulation of cellular response to stress GO:0080135 159 0.782
cytokinetic process GO:0032506 2 0.781
skeletal myofibril assembly GO:0014866 4 0.777
positive regulation of filopodium assembly GO:0051491 10 0.772
Fly
developmental maturation GO:0021700 193 0.772
Fly
regulation of rho protein signal transduction GO:0035023 71 0.768
organelle fission GO:0048285 170 0.766
Mouse
telencephalon development GO:0021537 186 0.766
embryonic organ morphogenesis GO:0048562 276 0.764
protein catabolic process GO:0030163 221 0.761
Mouse
regulation of cytokinesis GO:0032465 5 0.761
ribose phosphate metabolic process GO:0019693 291 0.761
ribonucleoside triphosphate metabolic process GO:0009199 220 0.759
purine ribonucleoside catabolic process GO:0046130 205 0.759
nucleotide catabolic process GO:0009166 217 0.758
protein localization to nucleus GO:0034504 121 0.756
cerebral cortex radially oriented cell migration GO:0021799 31 0.756
mitotic cell cycle GO:0000278 195 0.755
Mouse
regulation of jnk cascade GO:0046328 62 0.753
blood vessel morphogenesis GO:0048514 285 0.751
establishment or maintenance of cell polarity GO:0007163 86 0.749
Mouse Fly
hair follicle cell proliferation GO:0071335 3 0.743
Mouse
regulation of anatomical structure size GO:0090066 178 0.742
forebrain development GO:0030900 302 0.738
nucleocytoplasmic transport GO:0006913 139 0.731
digestive tract morphogenesis GO:0048546 147 0.730
Fly
actin filament depolymerization GO:0030042 15 0.728
purine nucleoside metabolic process GO:0042278 241 0.723
neural precursor cell proliferation GO:0061351 121 0.721
actin filament capping GO:0051693 6 0.712
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.712
regulation of stress fiber assembly GO:0051492 15 0.711
Human
cellular response to osmotic stress GO:0071470 7 0.707
actin polymerization or depolymerization GO:0008154 54 0.706
cellular amine metabolic process GO:0044106 44 0.698
regulation of synapse assembly GO:0051963 29 0.691
Fly
acetate ester transport GO:1901374 2 0.691
glial cell differentiation GO:0010001 131 0.688
positive regulation of cell development GO:0010720 237 0.681
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.681
actin cytoskeleton reorganization GO:0031532 21 0.679
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.678
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.676
stress activated protein kinase signaling cascade GO:0031098 81 0.676
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.675
Human Fly
establishment of tissue polarity GO:0007164 28 0.675
stress activated mapk cascade GO:0051403 80 0.672
Fly
ion transmembrane transport GO:0034220 361 0.671
muscle cell differentiation GO:0042692 261 0.667
Fly
regulation of organelle organization GO:0033043 289 0.666
regulation of nucleotide catabolic process GO:0030811 122 0.665
regulation of mapk cascade GO:0043408 248 0.664
Mouse
organelle assembly GO:0070925 177 0.659
striated muscle tissue development GO:0014706 293 0.654
Mouse
negative regulation of systemic arterial blood pressure GO:0003085 15 0.647
acetylcholine transport GO:0015870 2 0.645
actin filament branching GO:0090135 1 0.635
asymmetric stem cell division GO:0098722 3 0.632
regulation of stress activated mapk cascade GO:0032872 69 0.629
protein localization to organelle GO:0033365 185 0.628
organophosphate catabolic process GO:0046434 232 0.622
immune effector process GO:0002252 321 0.614
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.611
positive regulation of hair follicle cell proliferation GO:0071338 1 0.599
Mouse
positive regulation of ion transport GO:0043270 65 0.597
regulation of cellular ketone metabolic process GO:0010565 66 0.597
cellular copper ion homeostasis GO:0006878 8 0.596
regulation of purine nucleotide metabolic process GO:1900542 169 0.592
regulation of protein kinase c signaling GO:0090036 5 0.592
positive regulation of lamellipodium assembly GO:0010592 2 0.589
Human Mouse
regulation of establishment of planar polarity GO:0090175 28 0.588
nuclear transport GO:0051169 139 0.584
microtubule based transport GO:0010970 50 0.582
regulation of cell projection assembly GO:0060491 38 0.581
Human Mouse Fly
positive regulation of nucleoside metabolic process GO:0045979 91 0.580
amine metabolic process GO:0009308 45 0.576
regulation of neuron projection development GO:0010975 169 0.572
Fly
ossification GO:0001503 216 0.569
osmosensory signaling pathway GO:0007231 1 0.561
cellular amino acid metabolic process GO:0006520 103 0.552
cellular response to abiotic stimulus GO:0071214 56 0.550
intracellular protein transport GO:0006886 204 0.548
regulation of t cell activation GO:0050863 170 0.547
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.545
regulation of membrane potential GO:0042391 192 0.544
positive regulation of gtpase activity GO:0043547 85 0.544
multicellular organism growth GO:0035264 161 0.543
Mouse
oocyte anterior posterior axis specification GO:0007314 2 0.540
Fly
positive regulation of neutrophil chemotaxis GO:0090023 12 0.538
protein localization to membrane GO:0072657 108 0.536
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.535
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.533
blood circulation GO:0008015 195 0.532
Mouse
midbrain development GO:0030901 35 0.530
negative regulation of protein depolymerization GO:1901880 21 0.529
negative regulation of actin filament polymerization GO:0030837 11 0.529
positive regulation of wound healing GO:0090303 17 0.522
Fly
golgi localization GO:0051645 4 0.518
striated muscle cell development GO:0055002 125 0.511
Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.510
cell adhesion GO:0007155 329 0.509
positive regulation of podosome assembly GO:0071803 3 0.507
regulation of endocytosis GO:0030100 69 0.503
Worm
wnt signaling pathway GO:0016055 188 0.502
myosin filament organization GO:0031033 3 0.502
protein localization to cell junction GO:1902414 3 0.499
nucleoside triphosphate metabolic process GO:0009141 230 0.498
determination of left right symmetry GO:0007368 80 0.496
Fly
regulation of cellular component size GO:0032535 121 0.494
myofibril assembly GO:0030239 34 0.493
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.489
positive regulation of nucleotide catabolic process GO:0030813 88 0.485
cardiac muscle tissue development GO:0048738 130 0.480
Mouse
muscle tissue development GO:0060537 308 0.475
Mouse
lymphocyte anergy GO:0002249 4 0.474
regulation of intracellular transport GO:0032386 159 0.473
positive regulation of neutrophil migration GO:1902624 12 0.470
positive regulation of hydrolase activity GO:0051345 148 0.470
spindle localization GO:0051653 22 0.469
cytoplasmic transport GO:0016482 234 0.466
gland development GO:0048732 330 0.464
Fly
positive regulation of synapse assembly GO:0051965 18 0.464
telencephalon cell migration GO:0022029 55 0.462
positive regulation of organelle organization GO:0010638 128 0.461
muscle cell development GO:0055001 133 0.460
Fly
regulation of binding GO:0051098 111 0.459
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.456
cellular ketone metabolic process GO:0042180 84 0.456
macromolecule catabolic process GO:0009057 281 0.456
Mouse
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.449
melanin metabolic process GO:0006582 12 0.445
Fly
cell growth GO:0016049 130 0.437
Worm Fly
regulation of actin nucleation GO:0051125 4 0.437
single organism nuclear import GO:1902593 95 0.432
positive regulation of protein complex assembly GO:0031334 45 0.432
forebrain radial glial cell differentiation GO:0021861 4 0.431
positive regulation of lamellipodium organization GO:1902745 3 0.429
Human Mouse
neuron death GO:0070997 154 0.429
substrate independent telencephalic tangential migration GO:0021826 8 0.422
t cell anergy GO:0002870 4 0.421
positive regulation of cytoplasmic transport GO:1903651 40 0.421
regulation of mitotic cell cycle GO:0007346 126 0.421
Mouse
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.414
defense response to other organism GO:0098542 197 0.411
Fly
cellular protein complex assembly GO:0043623 116 0.408
neuron apoptotic process GO:0051402 142 0.407
response to organonitrogen compound GO:0010243 246 0.405
angiogenesis GO:0001525 201 0.405
protein import into nucleus GO:0006606 95 0.404
digestive system development GO:0055123 200 0.404
Fly
regulation of protein transport GO:0051223 163 0.403
negative regulation of transferase activity GO:0051348 85 0.401
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.401
morphogenesis of a branching epithelium GO:0061138 193 0.397
regulation of neuron death GO:1901214 134 0.395
chemotaxis GO:0006935 247 0.392
positive regulation of kinase activity GO:0033674 155 0.391
regulation of protein catabolic process GO:0042176 108 0.391
Mouse
hair follicle placode formation GO:0060789 5 0.389
Mouse
copper ion homeostasis GO:0055070 9 0.380
cell migration involved in gastrulation GO:0042074 13 0.380
Fly
cellular divalent inorganic cation homeostasis GO:0072503 127 0.379
synaptic transmission GO:0007268 329 0.379
Fly
gonad morphogenesis GO:0035262 1 0.378
regulation of cell activation GO:0050865 289 0.376
response to peptide hormone GO:0043434 127 0.373
regulation of cellular amino acid metabolic process GO:0006521 5 0.373
negative regulation of phosphorus metabolic process GO:0010563 184 0.372
positive regulation of cell cycle process GO:0090068 61 0.366
regulation of hair follicle cell proliferation GO:0071336 2 0.364
Mouse
tight junction assembly GO:0070830 9 0.363
regulation of rho gtpase activity GO:0032319 58 0.362
cellular lipid metabolic process GO:0044255 323 0.360
lipid localization GO:0010876 126 0.356
Fly
aromatic compound catabolic process GO:0019439 286 0.356
regulation of peptidyl serine phosphorylation GO:0033135 39 0.353
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.353
positive regulation of cell death GO:0010942 224 0.352
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.349
regulation of cell projection organization GO:0031344 206 0.343
Human Mouse Fly
wound healing GO:0042060 157 0.341
Fly
acetylcholine secretion neurotransmission GO:0014055 2 0.339
cerebral cortex development GO:0021987 86 0.338
positive regulation of intracellular protein transport GO:0090316 42 0.334
regulation of nuclear division GO:0051783 56 0.333
Mouse
regulation of intracellular protein transport GO:0033157 82 0.332
intracellular receptor signaling pathway GO:0030522 74 0.329
positive regulation of protein transport GO:0051222 93 0.328
arp2 3 complex mediated actin nucleation GO:0034314 3 0.328
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.326
heart process GO:0003015 94 0.326
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.326
regulation of transporter activity GO:0032409 57 0.325
regulation of lymphocyte anergy GO:0002911 4 0.322
regulation of protein import into nucleus GO:0042306 52 0.321
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.321
membrane invagination GO:0010324 17 0.319
granulocyte chemotaxis GO:0071621 39 0.319
morphogenesis of embryonic epithelium GO:0016331 159 0.319
Fly
cellular response to dna damage stimulus GO:0006974 207 0.317
Fly
positive regulation of apoptotic signaling pathway GO:2001235 95 0.316
regulation of t cell anergy GO:0002667 4 0.316
body morphogenesis GO:0010171 45 0.315
Worm
regulation of protein localization to nucleus GO:1900180 60 0.313
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.311
axonogenesis GO:0007409 274 0.310
multi organism reproductive behavior GO:0044705 29 0.305
Fly
establishment of neuroblast polarity GO:0045200 1 0.302
regulation of cardiac cell fate specification GO:2000043 1 0.301
regulation of ion transmembrane transport GO:0034765 119 0.299
schwann cell proliferation GO:0014010 2 0.298
neuromuscular process GO:0050905 99 0.298
Mouse
stem cell proliferation GO:0072089 117 0.297
spermatogenesis GO:0007283 284 0.297
response to oxidative stress GO:0006979 123 0.296
morphogenesis of a polarized epithelium GO:0001738 37 0.296
regulation of ion transport GO:0043269 215 0.296
regulation of neuron apoptotic process GO:0043523 122 0.294
regulation of nucleotide metabolic process GO:0006140 169 0.294
gonad development GO:0008406 141 0.293
Worm
keratinocyte differentiation GO:0030216 48 0.291
Mouse
negative regulation of molecular function GO:0044092 258 0.289
regulation of lymphocyte activation GO:0051249 240 0.289
maintenance of location GO:0051235 89 0.286
Fly
cation homeostasis GO:0055080 212 0.280
myosin filament assembly GO:0031034 2 0.279
regulation of blood pressure GO:0008217 93 0.279
positive regulation of substrate adhesion dependent cell spreading GO:1900026 8 0.278
Human
regulation of map kinase activity GO:0043405 120 0.276
regulation of ion transmembrane transporter activity GO:0032412 54 0.274
regulation of neuron differentiation GO:0045664 281 0.274
Fly
purine nucleoside triphosphate catabolic process GO:0009146 203 0.273
regulation of protein targeting GO:1903533 61 0.273
protein targeting GO:0006605 143 0.272
negative regulation of multi organism process GO:0043901 68 0.271
forebrain cell migration GO:0021885 58 0.268
transmembrane transport GO:0055085 412 0.267
sterol import GO:0035376 2 0.266
positive regulation of synapse structural plasticity GO:0051835 1 0.265
regulation of cation channel activity GO:2001257 22 0.265
regulation of mitosis GO:0007088 29 0.257
Mouse
negative regulation of phosphorylation GO:0042326 166 0.255
neuroblast proliferation GO:0007405 49 0.255
neural nucleus development GO:0048857 22 0.253
submandibular salivary gland formation GO:0060661 1 0.253
regulation of protein serine threonine kinase activity GO:0071900 157 0.251
Fly
salivary gland morphogenesis GO:0007435 33 0.250
Fly
contact inhibition GO:0060242 3 0.249
digestive tract development GO:0048565 190 0.249
Fly
establishment or maintenance of neuroblast polarity GO:0045196 1 0.244
protein depolymerization GO:0051261 34 0.244
glutamate receptor signaling pathway GO:0007215 35 0.241
gastrulation GO:0007369 116 0.240
Fly
cellular response to growth factor stimulus GO:0071363 197 0.239
negative regulation of cytoskeleton organization GO:0051494 36 0.239
negative regulation of neuron death GO:1901215 98 0.238
regulation of leukocyte proliferation GO:0070663 121 0.237
regulation of secretion by cell GO:1903530 249 0.235
positive regulation of apoptotic process GO:0043065 217 0.235
skeletal system development GO:0001501 356 0.234
negative regulation of protein modification process GO:0031400 163 0.233
cell type specific apoptotic process GO:0097285 268 0.232
protein localization to adherens junction GO:0071896 2 0.232
heart morphogenesis GO:0003007 178 0.232
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.232
Mouse
nuclear import GO:0051170 95 0.231
dna metabolic process GO:0006259 303 0.231
Rat
lateral line system development GO:0048925 1 0.230
negative regulation of cell development GO:0010721 169 0.229
positive regulation of cell cycle GO:0045787 92 0.228
developmental cell growth GO:0048588 84 0.227
Worm Fly
regulation of cytoplasmic transport GO:1903649 112 0.226
negative regulation of stress fiber assembly GO:0051497 4 0.226
cellular homeostasis GO:0019725 240 0.224
germ cell development GO:0007281 185 0.221
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.220
mapk cascade GO:0000165 281 0.218
Mouse Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.218
multi organism behavior GO:0051705 62 0.218
Fly
myeloid cell differentiation GO:0030099 233 0.218
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.216
t cell proliferation GO:0042098 120 0.215
establishment of organelle localization GO:0051656 122 0.215
Mouse
striated muscle myosin thick filament assembly GO:0071688 1 0.212
establishment or maintenance of actin cytoskeleton polarity GO:0030950 1 0.212
oocyte construction GO:0007308 2 0.211
Fly
establishment of endothelial blood brain barrier GO:0014045 3 0.210
regulation of vesicle mediated transport GO:0060627 139 0.209
Worm
positive regulation of map kinase activity GO:0043406 84 0.207
maintenance of apical basal cell polarity GO:0035090 3 0.206
response to amine GO:0014075 16 0.205
protein processing GO:0016485 163 0.205
cellular chemical homeostasis GO:0055082 215 0.204
actin filament based movement GO:0030048 23 0.203
regulation of secretion GO:0051046 274 0.203
spermatid development GO:0007286 108 0.203
attachment of spindle microtubules to kinetochore GO:0008608 4 0.201
positive regulation of cell division GO:0051781 31 0.200
mesoderm development GO:0007498 100 0.199
Fly
keratinocyte development GO:0003334 10 0.199
Mouse
positive regulation of cell migration GO:0030335 109 0.198
response to inorganic substance GO:0010035 96 0.198
cell substrate adhesion GO:0031589 130 0.198
regulation of neurotransmitter levels GO:0001505 87 0.197
stem cell division GO:0017145 30 0.197
negative regulation of intracellular signal transduction GO:1902532 167 0.197
nuclear division GO:0000280 158 0.197
Mouse
positive regulation of granulocyte chemotaxis GO:0071624 12 0.196
regulation of neural precursor cell proliferation GO:2000177 70 0.195
pole plasm assembly GO:0007315 2 0.195
Fly
multi multicellular organism process GO:0044706 109 0.194
positive regulation of amine transport GO:0051954 8 0.194
positive regulation of secretion by cell GO:1903532 114 0.193
positive regulation of mapk cascade GO:0043410 170 0.191
Mouse
glial cell migration GO:0008347 7 0.190
Fly
plasma membrane organization GO:0007009 90 0.189
response to peptide GO:1901652 136 0.188
bmp signaling pathway GO:0030509 93 0.185
regulation of metal ion transport GO:0010959 106 0.184
modification dependent protein catabolic process GO:0019941 133 0.181
positive regulation of growth GO:0045927 104 0.180
sensory perception of umami taste GO:0050917 4 0.179
proteasomal protein catabolic process GO:0010498 98 0.178
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.178
organic hydroxy compound metabolic process GO:1901615 203 0.178
Fly
negative regulation of protein complex assembly GO:0031333 25 0.178
olfactory bulb development GO:0021772 30 0.177
granulocyte migration GO:0097530 43 0.175
extracellular structure organization GO:0043062 148 0.175
epithelial mesenchymal cell signaling GO:0060684 7 0.175
Mouse
neurotransmitter secretion GO:0007269 62 0.174
spindle assembly involved in mitosis GO:0090307 4 0.173
regulation of cellular catabolic process GO:0031329 242 0.173
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.172
Mouse
lymphocyte proliferation GO:0046651 164 0.171
regulation of multi organism process GO:0043900 111 0.171
developmental growth involved in morphogenesis GO:0060560 138 0.171
Worm Fly
rhythmic process GO:0048511 174 0.171
molting cycle GO:0042303 90 0.170
Mouse
regulation of podosome assembly GO:0071801 3 0.169
neuron maturation GO:0042551 29 0.168
regulation of protein stability GO:0031647 52 0.167
Mouse
positive regulation of intracellular transport GO:0032388 70 0.167
regulation of organ morphogenesis GO:2000027 144 0.164
positive regulation of lymphocyte anergy GO:0002913 4 0.163
ameboidal type cell migration GO:0001667 128 0.163
Fly
epithelial tube morphogenesis GO:0060562 303 0.163
neutrophil chemotaxis GO:0030593 36 0.163
positive regulation of secretion GO:0051047 130 0.162
anatomical structure arrangement GO:0048532 20 0.162
regulation of lipid metabolic process GO:0019216 118 0.162
peptidyl serine modification GO:0018209 83 0.161
Mouse
regulation of response to wounding GO:1903034 189 0.158
Fly
regionalization GO:0003002 337 0.158
Fly
regulation of protein complex disassembly GO:0043244 28 0.158
dna replication GO:0006260 52 0.157
Rat
purine nucleotide metabolic process GO:0006163 302 0.155
cation transmembrane transport GO:0098655 266 0.154
regulation of nucleocytoplasmic transport GO:0046822 73 0.154
endocytosis GO:0006897 168 0.154
locomotory behavior GO:0007626 195 0.153
positive regulation of jnk cascade GO:0046330 46 0.153
regulation of kinase activity GO:0043549 249 0.152

Rac1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.217
disease of cellular proliferation DOID:14566 0 0.217