|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.853
|
Human |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.760
|
Mouse Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.661
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.568
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.566
|
Mouse Worm Fly |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.556
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.534
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.533
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.530
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.472
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.456
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.454
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.417
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.352
|
Mouse Fly |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.350
|
Human Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.350
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.344
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.329
|
Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.302
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.297
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.283
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.276
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.275
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.269
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.256
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.254
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.249
|
Mouse Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.247
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.244
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.237
|
Zebrafish Fly |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.217
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.212
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.210
|
Mouse Fly |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.209
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.205
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.203
|
Mouse Fly |
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.203
|
Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.197
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.193
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.178
|
Human Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.176
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.174
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.169
|
Human |
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.169
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.168
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.168
|
Fly |
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.167
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.165
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.165
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.159
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.155
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.155
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.153
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.153
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.151
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.151
|
Fly |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.144
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.142
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.139
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.132
|
Mouse Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.132
|
Mouse Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.129
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.127
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.124
|
Human Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.122
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.113
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.113
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.113
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.112
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.111
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.111
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.108
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.106
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.104
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.104
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.102
|
Mouse |
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.100
|
Mouse |
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.097
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.096
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.095
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.094
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.094
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.093
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.092
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.091
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.089
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.089
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.088
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.088
|
Mouse Fly |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.086
|
Fly |
|
|
t cell selection
|
GO:0045058 |
34 |
0.086
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.085
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.085
|
Mouse Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.083
|
Mouse |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.083
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.083
|
Zebrafish |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.083
|
Human Mouse Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.082
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.082
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.081
|
Mouse Worm Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.078
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.077
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.077
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.077
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.077
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.077
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.076
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.076
|
Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.075
|
Fly |
|
|
neuron migration
|
GO:0001764 |
122 |
0.075
|
Worm |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.075
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.072
|
Mouse Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.072
|
Mouse |
|
|
pallium development
|
GO:0021543 |
120 |
0.072
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.071
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.071
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.070
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.070
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.069
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.069
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.068
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.068
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.068
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.067
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.067
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.067
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.066
|
Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.066
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.065
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.065
|
Human Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.065
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.065
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.064
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.064
|
Fly |
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.063
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.063
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.062
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.062
|
Fly |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.061
|
Fly |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.061
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.061
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.061
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.060
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.060
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.060
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.060
|
Fly |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.059
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.059
|
Mouse Fly |
|
|
cation transport
|
GO:0006812 |
399 |
0.058
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.058
|
Mouse Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.057
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.057
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.056
|
|
|
|
macula densa development
|
GO:0072024 |
1 |
0.056
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.056
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.056
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.056
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.056
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.055
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.055
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.055
|
Mouse Fly |
|
|
b cell activation
|
GO:0042113 |
161 |
0.055
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.055
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.054
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.054
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.053
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.053
|
Mouse Fly |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.053
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.053
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.052
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.052
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.052
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.051
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.051
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.050
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.050
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.050
|
|
|
|
positive regulation of semaphorin plexin signaling pathway
|
GO:2001262 |
1 |
0.049
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.049
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.048
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.048
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.048
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.048
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.047
|
Mouse |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.047
|
Fly |
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.047
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.047
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.046
|
Mouse |
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.046
|
Mouse Worm Fly |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.046
|
Mouse |
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.045
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.045
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.045
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.045
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.044
|
Mouse Fly |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.044
|
Zebrafish Mouse Fly |
|
|
gland development
|
GO:0048732 |
330 |
0.043
|
Fly |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.043
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.043
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.043
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.043
|
Fly |
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.042
|
Zebrafish |
|
|
negative regulation of myeloid dendritic cell activation
|
GO:0030886 |
3 |
0.042
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.042
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.041
|
Fly |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.041
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.041
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.040
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.040
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.040
|
Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.040
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.040
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.040
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.039
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.039
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.039
|
Fly |
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.039
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.039
|
Mouse |
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.039
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.039
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.038
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.038
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.038
|
Mouse Worm Fly |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.038
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.038
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.038
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.038
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.037
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.037
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.037
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.037
|
Mouse |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.036
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.036
|
Worm |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.036
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.036
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.036
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.036
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.035
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.035
|
Fly |
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.035
|
Mouse |
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.035
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.035
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.035
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.035
|
Fly |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.034
|
Mouse |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.034
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.034
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.034
|
Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.034
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.034
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.034
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.034
|
Fly |
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.034
|
Mouse |
|
|
cell maturation
|
GO:0048469 |
127 |
0.034
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.034
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.034
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.033
|
Mouse |
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.033
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.033
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.033
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.033
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.033
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.032
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.032
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.032
|
Mouse |
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.032
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.032
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.032
|
Fly |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.032
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.032
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.032
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.031
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.031
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.031
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.031
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.031
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.031
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.031
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.031
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.031
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.031
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.031
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.031
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.031
|
Mouse Fly |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.030
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.030
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.030
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.030
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.030
|
Mouse Worm |
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.030
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.030
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.030
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.030
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.030
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.030
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.029
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.029
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.029
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.029
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.029
|
Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.029
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.029
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.028
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.028
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.028
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.028
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.028
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.028
|
Mouse |
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.028
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.028
|
Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.027
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.027
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.027
|
Mouse |
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.027
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.027
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.027
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.027
|
|
|
|
learning
|
GO:0007612 |
98 |
0.027
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.026
|
Mouse |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.026
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.026
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.026
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.026
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.026
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.026
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.026
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.026
|
Mouse |
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.026
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.026
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.025
|
Fly |
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.025
|
Worm |
|
|
activation of rac gtpase activity
|
GO:0032863 |
2 |
0.025
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.025
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.025
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.025
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.025
|
Worm |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.025
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.025
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.025
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.025
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.025
|
Mouse |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.025
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.025
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.024
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.024
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.024
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.024
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.024
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.024
|
Mouse Fly |
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.024
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.024
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.024
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.024
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.024
|
Zebrafish |
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.024
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.024
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.024
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.023
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.023
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.023
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.023
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.023
|
Fly |
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.023
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.023
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.023
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.023
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.022
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.022
|
Fly |
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.022
|
Fly |
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.022
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.022
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.022
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.022
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.022
|
Mouse Fly |
|
|
glucose transport
|
GO:0015758 |
56 |
0.022
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
1 |
0.022
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
24 |
0.022
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.022
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.021
|
Mouse |
|
|
synapse organization
|
GO:0050808 |
125 |
0.021
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.021
|
Mouse |
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.021
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.021
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.021
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.021
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.021
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.021
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.021
|
Zebrafish |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.021
|
Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.021
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.021
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.021
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
31 |
0.021
|
Mouse |
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.021
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.021
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.021
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.020
|
Worm Fly |
|
|
nk t cell differentiation
|
GO:0001865 |
8 |
0.020
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.020
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.020
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.020
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.020
|
Fly |
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.020
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.020
|
Fly |
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.020
|
Fly |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.020
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.020
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.020
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.020
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.020
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.020
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.020
|
Fly |
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.020
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.020
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.020
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.020
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.020
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.020
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.020
|
|
|
|
aortic valve morphogenesis
|
GO:0003180 |
4 |
0.020
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.020
|
Fly |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.019
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.019
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
18 |
0.019
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.019
|
Fly |
|
|
cell growth
|
GO:0016049 |
130 |
0.019
|
Worm Fly |
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.019
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.019
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.019
|
Fly |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.019
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.019
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.019
|
Fly |
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.019
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.019
|
|
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.019
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.019
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.019
|
|
|
|
parallel actin filament bundle assembly
|
GO:0030046 |
2 |
0.019
|
|
|
|
endoderm formation
|
GO:0001706 |
20 |
0.019
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.019
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.019
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.018
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.018
|
Fly |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.018
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.018
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
3 |
0.018
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.018
|
|
|
|
sphingosine 1 phosphate signaling pathway
|
GO:0003376 |
3 |
0.018
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.018
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.018
|
|
|
|
toll like receptor 9 signaling pathway
|
GO:0034162 |
6 |
0.018
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.018
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.018
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.018
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.018
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.018
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.018
|
Mouse |
|
|
regulation of bone resorption
|
GO:0045124 |
24 |
0.018
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.018
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.018
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.018
|
|
|
|
leukocyte aggregation
|
GO:0070486 |
1 |
0.018
|
Human |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.018
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.018
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.018
|
Mouse |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.018
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.018
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.018
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.017
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.017
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.017
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.017
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.017
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.017
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.017
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.017
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.017
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.017
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.017
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.017
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.017
|
Mouse Fly |
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.017
|
Mouse |
|
|
tolerance induction
|
GO:0002507 |
14 |
0.017
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.017
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.017
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.017
|
Mouse |
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.017
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.017
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.017
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.016
|
|
