Mus musculus

43 known processes

Ran

RAN, member RAS oncogene family

Ran biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based process GO:0007017 236 0.640
cellular macromolecule catabolic process GO:0044265 206 0.529
dna metabolic process GO:0006259 303 0.513
regulation of polyamine transmembrane transport GO:1902267 5 0.475
microtubule cytoskeleton organization GO:0000226 157 0.451
regulation of establishment of protein localization GO:0070201 181 0.438
cellular response to dna damage stimulus GO:0006974 207 0.401
alpha amino acid metabolic process GO:1901605 59 0.361
protein targeting GO:0006605 143 0.286
spindle assembly involved in mitosis GO:0090307 4 0.271
protein dna complex subunit organization GO:0071824 28 0.266
organelle fission GO:0048285 170 0.254
ubiquitin dependent protein catabolic process GO:0006511 129 0.222
sperm egg recognition GO:0035036 37 0.202
recombinational repair GO:0000725 21 0.165
lymphocyte proliferation GO:0046651 164 0.162
oocyte anterior posterior axis specification GO:0007314 2 0.151
regulation of intracellular protein transport GO:0033157 82 0.151
mitotic cell cycle process GO:1903047 159 0.151
nitrogen compound transport GO:0071705 271 0.149
histone acetylation GO:0016573 41 0.136
regulation of cell cycle GO:0051726 281 0.136
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.135
cell cell recognition GO:0009988 44 0.133
regulation of nucleocytoplasmic transport GO:0046822 73 0.131
mitotic spindle organization GO:0007052 10 0.131
protein catabolic process GO:0030163 221 0.126
transcription coupled nucleotide excision repair GO:0006283 2 0.126
organophosphate biosynthetic process GO:0090407 122 0.117
posttranscriptional regulation of gene expression GO:0010608 155 0.117
regulation of intracellular transport GO:0032386 159 0.117
mitotic cell cycle GO:0000278 195 0.116
modification dependent protein catabolic process GO:0019941 133 0.106
cellular amine metabolic process GO:0044106 44 0.102
extracellular matrix organization GO:0030198 147 0.102
macromolecule catabolic process GO:0009057 281 0.095
cytoplasmic transport GO:0016482 234 0.093
nucleocytoplasmic transport GO:0006913 139 0.092
regulation of protein localization GO:0032880 231 0.092
single fertilization GO:0007338 82 0.091
amine metabolic process GO:0009308 45 0.090
modification dependent macromolecule catabolic process GO:0043632 133 0.090
fertilization GO:0009566 127 0.087
nuclear division GO:0000280 158 0.087
protein localization to nucleus GO:0034504 121 0.087
regulation of transmembrane transport GO:0034762 128 0.086
negative regulation of cellular protein metabolic process GO:0032269 247 0.082
chromatin organization GO:0006325 206 0.080
gonad development GO:0008406 141 0.079
positive regulation of protein modification process GO:0031401 299 0.077
dna replication GO:0006260 52 0.075
regulation of cytoplasmic transport GO:1903649 112 0.075
mitotic nuclear division GO:0007067 48 0.074
circulatory system process GO:0003013 197 0.073
polyamine transmembrane transport GO:1902047 5 0.072
peptidyl amino acid modification GO:0018193 336 0.070
internal peptidyl lysine acetylation GO:0018393 42 0.068
development of primary sexual characteristics GO:0045137 143 0.067
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.064
nucleotide metabolic process GO:0009117 332 0.063
blood circulation GO:0008015 195 0.063
oocyte construction GO:0007308 2 0.062
positive regulation of protein export from nucleus GO:0046827 4 0.060
aromatic compound catabolic process GO:0019439 286 0.060
positive regulation of cellular amine metabolic process GO:0033240 5 0.059
chromatin silencing GO:0006342 15 0.058
rna localization GO:0006403 23 0.056
body morphogenesis GO:0010171 45 0.055
spindle organization GO:0007051 28 0.054
chromatin modification GO:0016568 187 0.054
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.052
response to inorganic substance GO:0010035 96 0.052
organelle localization GO:0051640 179 0.052
heart contraction GO:0060047 93 0.051
protein maturation GO:0051604 176 0.050
embryonic organ morphogenesis GO:0048562 276 0.050
protein import into nucleus GO:0006606 95 0.048
protein methylation GO:0006479 81 0.048
cellular amino acid metabolic process GO:0006520 103 0.047
sensory organ morphogenesis GO:0090596 242 0.047
small molecule biosynthetic process GO:0044283 132 0.046
binding of sperm to zona pellucida GO:0007339 34 0.045
protein import GO:0017038 101 0.045
nucleobase containing compound transport GO:0015931 27 0.045
regulation of ion transmembrane transport GO:0034765 119 0.044
regulation of protein transport GO:0051223 163 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
negative regulation of molecular function GO:0044092 258 0.044
polyamine transport GO:0015846 5 0.043
heart process GO:0003015 94 0.043
dna dealkylation GO:0035510 11 0.041
regulation of cellular catabolic process GO:0031329 242 0.041
single organism nuclear import GO:1902593 95 0.041
nuclear export GO:0051168 34 0.040
oxidation reduction process GO:0055114 342 0.040
intracellular protein transport GO:0006886 204 0.040
cellular lipid metabolic process GO:0044255 323 0.039
monocarboxylic acid metabolic process GO:0032787 191 0.039
carboxylic acid biosynthetic process GO:0046394 86 0.038
ossification GO:0001503 216 0.038
muscle system process GO:0003012 141 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
peptidyl lysine acetylation GO:0018394 45 0.036
nuclear transport GO:0051169 139 0.035
nucleotide biosynthetic process GO:0009165 78 0.034
i kappab kinase nf kappab signaling GO:0007249 85 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
nucleoside phosphate biosynthetic process GO:1901293 79 0.032
hemostasis GO:0007599 78 0.032
regulation of heart contraction GO:0008016 77 0.032
regulation of mapk cascade GO:0043408 248 0.032
regulation of cellular component biogenesis GO:0044087 181 0.032
mrna processing GO:0006397 63 0.031
transmembrane transport GO:0055085 412 0.031
regulation of cell activation GO:0050865 289 0.031
protein export from nucleus GO:0006611 20 0.030
regulation of protein import into nucleus GO:0042306 52 0.030
regulation of rna splicing GO:0043484 37 0.030
spindle assembly GO:0051225 13 0.030
camera type eye development GO:0043010 266 0.029
proteasomal protein catabolic process GO:0010498 98 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.029
heterocycle catabolic process GO:0046700 280 0.029
positive regulation of transmembrane transport GO:0034764 29 0.028
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.028
lipid biosynthetic process GO:0008610 179 0.028
cell recognition GO:0008037 83 0.028
nuclear import GO:0051170 95 0.027
cellular homeostasis GO:0019725 240 0.027
regulation of system process GO:0044057 200 0.027
dna modification GO:0006304 50 0.026
regulation of protein targeting GO:1903533 61 0.026
genitalia development GO:0048806 37 0.026
leukocyte migration GO:0050900 124 0.026
epithelial cell proliferation GO:0050673 174 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
regulation of mrna splicing via spliceosome GO:0048024 32 0.026
polyamine biosynthetic process GO:0006596 2 0.025
female gamete generation GO:0007292 74 0.025
regulation of cellular response to stress GO:0080135 159 0.025
regulation of hormone levels GO:0010817 211 0.025
determination of heart left right asymmetry GO:0061371 48 0.024
regulation of actin filament based process GO:0032970 99 0.024
protein ubiquitination GO:0016567 171 0.024
protein localization to organelle GO:0033365 185 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
cellular response to lipid GO:0071396 145 0.024
positive regulation of intracellular transport GO:0032388 70 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
spermatogenesis GO:0007283 284 0.023
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.023
wound healing GO:0042060 157 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
endocytosis GO:0006897 168 0.023
establishment of rna localization GO:0051236 18 0.023
mapk cascade GO:0000165 281 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
response to metal ion GO:0010038 47 0.022
regulation of protein catabolic process GO:0042176 108 0.022
hydrogen peroxide catabolic process GO:0042744 5 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
cellular protein catabolic process GO:0044257 155 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
mrna catabolic process GO:0006402 22 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
regulation of muscle system process GO:0090257 80 0.021
chromatin assembly GO:0031497 13 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
cellular ketone metabolic process GO:0042180 84 0.021
dna templated transcription elongation GO:0006354 13 0.021
small gtpase mediated signal transduction GO:0007264 97 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
response to organic cyclic compound GO:0014070 198 0.020
gland development GO:0048732 330 0.020
positive regulation of dna repair GO:0045739 3 0.020
ras protein signal transduction GO:0007265 77 0.019
alternative mrna splicing via spliceosome GO:0000380 12 0.019
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.019
actin cytoskeleton organization GO:0030036 220 0.019
germ cell proliferation GO:0036093 7 0.019
cell cycle checkpoint GO:0000075 47 0.019
positive regulation of rna splicing GO:0033120 12 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.019
photoreceptor cell development GO:0042461 40 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
cytoplasmic microtubule organization GO:0031122 14 0.018
pole plasm assembly GO:0007315 2 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.018
cation transport GO:0006812 399 0.018
extracellular structure organization GO:0043062 148 0.018
rna splicing via transesterification reactions GO:0000375 43 0.018
regulation of ion transport GO:0043269 215 0.018
internal protein amino acid acetylation GO:0006475 42 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
positive regulation of protein transport GO:0051222 93 0.018
regulation of blood circulation GO:1903522 93 0.017
fatty acid metabolic process GO:0006631 121 0.017
mitotic cytokinesis GO:0000281 4 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
cell fate commitment GO:0045165 210 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
response to acid chemical GO:0001101 111 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of embryonic development GO:0045995 71 0.017
mrna metabolic process GO:0016071 84 0.017
membrane organization GO:0061024 245 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
gtp metabolic process GO:0046039 144 0.017
stress activated mapk cascade GO:0051403 80 0.017
regulation of protein export from nucleus GO:0046825 11 0.017
placenta development GO:0001890 140 0.017
regulation of transporter activity GO:0032409 57 0.017
translation GO:0006412 93 0.017
cellular protein complex assembly GO:0043623 116 0.016
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.016
forebrain development GO:0030900 302 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
regulation of transferase activity GO:0051338 263 0.016
response to steroid hormone GO:0048545 56 0.016
rna splicing GO:0008380 54 0.016
negative regulation of cardiac muscle hypertrophy GO:0010614 9 0.016
maternal process involved in female pregnancy GO:0060135 32 0.016
cellular response to inorganic substance GO:0071241 37 0.015
positive regulation of proteolysis GO:0045862 85 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
positive regulation of dna templated transcription elongation GO:0032786 2 0.015
maternal placenta development GO:0001893 20 0.015
palate development GO:0060021 76 0.015
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.015
receptor mediated endocytosis GO:0006898 51 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of protein stability GO:0031647 52 0.014
nls bearing protein import into nucleus GO:0006607 2 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
protein acylation GO:0043543 64 0.014
histone modification GO:0016570 159 0.014
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.014
dna integrity checkpoint GO:0031570 28 0.014
response to reactive oxygen species GO:0000302 56 0.014
leukocyte proliferation GO:0070661 172 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
regulation of kinase activity GO:0043549 249 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
positive regulation of transferase activity GO:0051347 167 0.014
regulation of map kinase activity GO:0043405 120 0.014
purine containing compound catabolic process GO:0072523 213 0.014
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of exit from mitosis GO:0007096 1 0.013
positive regulation of mrna metabolic process GO:1903313 17 0.013
positive regulation of kinase activity GO:0033674 155 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of body fluid levels GO:0050878 162 0.013
cofactor metabolic process GO:0051186 80 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
protein alkylation GO:0008213 81 0.013
tissue homeostasis GO:0001894 115 0.013
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
peptidyl lysine modification GO:0018205 77 0.013
negative regulation of immune system process GO:0002683 209 0.013
telencephalon development GO:0021537 186 0.013
regulation of hydrolase activity GO:0051336 246 0.013
regulation of protein localization to nucleus GO:1900180 60 0.013
mrna export from nucleus GO:0006406 11 0.013
response to organonitrogen compound GO:0010243 246 0.012
lateral inhibition GO:0046331 1 0.012
leukocyte differentiation GO:0002521 342 0.012
segmentation GO:0035282 93 0.012
t cell activation GO:0042110 289 0.012
positive regulation of organelle organization GO:0010638 128 0.012
response to hydrogen peroxide GO:0042542 32 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
negative regulation of cell activation GO:0050866 111 0.012
proteasome assembly GO:0043248 1 0.012
regulation of binding GO:0051098 111 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
divalent metal ion transport GO:0070838 172 0.012
regulation of stress activated mapk cascade GO:0032872 69 0.012
protein folding GO:0006457 28 0.012
chemotaxis GO:0006935 247 0.012
positive regulation of cytoplasmic transport GO:1903651 40 0.012
mesenchyme development GO:0060485 152 0.011
regulation of protein binding GO:0043393 60 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.011
negative regulation of leukocyte differentiation GO:1902106 51 0.011
respiratory system development GO:0060541 190 0.011
positive regulation of intracellular protein transport GO:0090316 42 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
male gamete generation GO:0048232 285 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of t cell activation GO:0050863 170 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
oocyte axis specification GO:0007309 2 0.011
superoxide metabolic process GO:0006801 27 0.011
glial cell differentiation GO:0010001 131 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of protein kinase activity GO:0045859 232 0.011
positive regulation of endopeptidase activity GO:0010950 43 0.011
response to growth factor GO:0070848 198 0.011
tissue migration GO:0090130 68 0.011
organic acid biosynthetic process GO:0016053 86 0.010
regulation of protein ubiquitination GO:0031396 52 0.010
regulation of transcription factor import into nucleus GO:0042990 24 0.010
regulation of lamellipodium assembly GO:0010591 3 0.010
cellular response to external stimulus GO:0071496 88 0.010
amide transport GO:0042886 138 0.010
lamellipodium organization GO:0097581 29 0.010
chromatin remodeling GO:0006338 32 0.010
4 hydroxyproline metabolic process GO:0019471 5 0.010
response to alcohol GO:0097305 48 0.010

Ran disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.013
colon cancer DOID:219 0 0.013
gastrointestinal system cancer DOID:3119 0 0.013
intestinal cancer DOID:10155 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
colorectal cancer DOID:9256 0 0.013